CN103239639A - Traditional Chinese medicine for treating anaphylactoid purpura - Google Patents
Traditional Chinese medicine for treating anaphylactoid purpura Download PDFInfo
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Abstract
The invention provides traditional Chinese medicine for treating anaphylactoid purpura. The traditional Chinese medicine comprises the following components in parts by weight: 28-32 parts of gypsum, 12-18 parts of rehmannia root, 9-15 parts of radix scrophulariae, 7-11 parts of bamboo leaves, 9-15 parts of rhizoma anemarrhenae, 9-15 parts of common peony root, 12-18 parts of cortex moutan, 12-18 parts of fructus forsythia, 2-4 parts of rhizoma coptidis, 12-18 parts of baical skullcap root, 12-18 parts of sinkiang arnebia root and 9-15 parts of sophora flower. Compared with the prior art, the traditional Chinese medicine is capable of treating internal pathogenic factors of anaphylactoid purpura according to different symptoms and treating both symptoms and root causes, and is quick in curative effect, low in cost, free of toxic or side effects and remarkable in effect.
Description
Technical field
The present invention relates to a kind of Chinese medicine, more particularly, relate to a kind of Chinese medicine for the treatment of anaphylactoid purpura.
Background technology
Anaphylactoid purpura is a kind of allergic disease of blood capillary.Clinical characters is skin petechia, ecchymosis, is distributed in extremity more and stretches side and buttocks, and symmetry occurs in batches, and stomachache and arthralgia etc. are often arranged.Its pathogenesis mainly is owing to body causes that to some allergin generation allergy the permeability of capillary wall and fragility increase.Primary disease is more common in child and youth.Clinical skin-type (seeing at most), abdomen type, joint type, kidney type, mixed type five types of being divided into.As timely diagnosis and treatment, prognosis bona.Anaphylactoid purpura belongs to the traditional Chinese medical science " blood disorder ", " macule ", " hematohidrosis " category.Existing prescription is all not good enough on cure rate, treatment means and treatment cost, can not reach gratifying effect.Prior art needs a kind of respond well Chinese medicine preparation to replace above-mentioned therapeutic scheme.
Summary of the invention
The purpose of this invention is to provide a kind of Chinese medicine for the treatment of anaphylactoid purpura, it is at the inherent pathogenic factor of anaphylactoid purpura, distinguishes that disease executing control, and with strong points, curative effect is fast, and cost is low, and has no side effect, and can reach to play good prevention effect.
In order to realize above-mentioned purpose, the present invention by the following technical solutions: a kind of Chinese medicine for the treatment of anaphylactoid purpura, in weight portion, comprise following component: Gypsum Fibrosum 28-32, Radix Rehmanniae 12-18, Radix Scrophulariae 9-15, Folium Bambusae 7-11, Rhizoma Anemarrhenae 9-15, Radix Paeoniae Rubra 9-15, Cortex Moutan 12-18, Fructus Forsythiae 12-18, Rhizoma Coptidis 2-4, Radix Scutellariae 12-18, Radix Arnebiae (Radix Lithospermi) 12-18, Flos Sophorae 9-15.
The Analysis on Mechanism of Chinese medicine of the present invention:
Gypsum Fibrosum: hot, sweet, be slightly cold.Attach to the lung and stomach meridians.Clearing away heat-fire, relieving restlessness is quenched the thirst, the convergence granulation promoting.The matter of Gypsum Fibrosum, middle sulfur-bearing oxygen is with cool and can loose, and the power of expelling pathogenic factors from the exterior expelling pathogenic factors from muscles is arranged, diseases caused by exogenous pathogenic factor have excess-heat person, directly victory Jindan of using boldly and with confidence.(Zhang Xichun " Records of Tradition Chinese and Western Medicine in Combination " first volume).
The Radix Rehmanniae: sweet, cold.GUIXIN, liver, kidney channel.Clearing away heat and cooling blood, yin nourishing is promoted the production of body fluid.Be used for calentura crimson tongue excessive thirst, interior-heat caused by deficiency of YIN, the hectic fever due to YIN-deficiency consumptive fever, interior-heat is quenched one's thirst, and spits blood, and epistaxis is sent out the speckle dermexanthesis.
Radix Scrophulariae: sweet in the mouth, hardship, salty.Cold nature.Return lung, stomach, kidney channel.Clearing away heat and cooling blood, nourishing YIN to lower pathogenic fire, detoxicating and resolving stagnation of pathogens.Be used for warm febrile disease and nutrient blood, fever of the body, excessive thirst, crimson tongue is sent out speckle, the hectic fever due to YIN-deficiency chronic cough, fidgets due to deficiency is awake not, and constipation is hindered in Tianjin, and order is puckery dim-sighted, and the throat larynx swells and ache, scrofula sucutaneous nodule, skin sore." Japan hanako materia medica ": control wind syndrome of head pyretic toxicity urticaria, the tonify deficiency strain, the heart is frightened irritated, and bad weary hectic fever due to YIN-deficiency passes the corpse pathogen, and is only forgetful, the detumescence poison.
Folium Bambusae: sweet light, cold.Go into the heart, lung, gallbladder, stomach warp.Clearing heat and relieving fidgetness, the diuresis of promoting the production of body fluid.Be used for the calentura excessive thirst, Xiao Jing Epilepsy, cough with dyspnea is told nosebleed, oliguria with reddish urine, erosion of the oral mucosa tongue boil." property of medicine opinion ": main haematemesis pyretic toxicity wind, only quench one's thirst.
The Rhizoma Anemarrhenae: bitter, sweet, cold.Return lung, stomach, kidney channel.Clearing away heat-fire promotes the production of body fluid and moisturizes.Be used for the high Sheng of epidemic febrile disease pathogenic heat, lung excess of the stomach heat syndromes such as high fever, excessive thirst, full and large pulse." Japan hanako materia medica ": logical small intestinal, the expectorant antitussive, the profit cardiopulmonary, tonify deficiency is weary, and the spasmolytic of feeling at ease is throbbed with fear.
Radix Paeoniae Rubra: hardship is slightly cold.Return Liver Channel.Clearing away heat and cooling blood, eliminating stasis to stop pain.Be used for maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, lump in the abdomen stomachache, injury from falling down, carbuncle skin infection.
Cortex Moutan: arduous; Cool; Be slightly cold.GUIXIN; Liver; Kidney; Lung meridian.Heat clearing away; Promoting blood circulation to remove blood stasis.Be used for the pathogenic heat attacking blood system in febrile diseases, send out speckle, tell nosebleed, deficiency of YIN osteopyrexia and fever, amenorrhea due to stagnation of blood, dysmenorrhea, carbuncle sore tumefacting virus falls and pounces on the pain of injury, the rheumatism pyretic arthralgia." Japan hanako materia medica ": except pathogen, please color, the natural fibre line of meat blood vessels of being open to the custom, evacuation of pus, logical menstruation disappears and pounces on the damage blood stasis, reuniting the fractured tendons and bones, except migratory arthralgia, the tire lower eyelid that falls, puerperal all cold and hot vim and vigour.
Fructus Forsythiae: hardship; Cold nature.Return lung; The heart; Gallbladder meridian.Heat-clearing and toxic substances removing; Dispersing swelling and dissipating binds.Be used for anemopyretic cold, epidemic febrile disease, pyretic stranguria urine retention, carbuncle, toxic swelling, scrofula, goiter, sore throat." Japan hanako materia medica ": logical small intestinal, evacuation of pus.Control furuncle, pain relieving, logical menstruation.
Radix Paeoniae Alba (parched): picric acid, cold.Go into liver, spleen channel.Nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing is received antiperspirant." herbal classic ": main pathogen stomachache, broken hard long-pending except arthralgia due to stagnation of blood, control cold and heat hernia abdominal mass, pain relieving, diuresis, QI invigorating.
Rhizoma Coptidis: hardship, cold, nontoxic.GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.Heat clearing and damp drying, eliminating fire and detoxication.Be used for damp and hot feeling of fullness, the vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood is told nosebleed, conjunctival congestion, the carbuncle furuncle is quenched one's thirst in toothache; External treatment eczema, eczema, auditory meatus is suppurated." not Lu ": main the five internal organs are cold and hot, descend discharging pus and blood for a long time, only quench one's thirst, and be frightened, except the water conservancy bone, transfer the thick intestinal of stomach, and beneficial gallbladder is treated aphtha.
Radix Scutellariae: bitter in the mouth; Cold in nature.Return lung; The heart; Liver; Gallbladder; Large intestine channel.Clearing away heat-fire; The dampness detoxifcation; Hemostasis; Antiabortive.Be used for the cough due to lung-heat, the calentura unconsciousness due to high fever, the liver-fire headache, conjunctival congestion and swelling pain, jaundice due to damp-heat, dysentery, pyretic stranguria is told epistaxis, metrorrhagia, excessive fetal movement due to heat in pregnancy, carbuncle furuncle." not Lu ": treat expectorant heat, pathogenic heat in the stomach, little angina abdominis, rapid digestion of food, sharp small intestinal, woman's blood closes, and drenches to reveal hematochezia, abdominal pain in children.
Radix Arnebiae (Radix Lithospermi): cold in nature, sweet in the mouth, salty.GUIXIN, Liver Channel.Removing heat from blood, invigorate blood circulation the detoxifcation rash.Be used for that the heat in blood poison is contained, purple black, the measles without adequate eruption of macule, skin infection, eczema, burn due to hot liquid or fire." detailed outline ": control macule, pox poison, promoting blood circulation and cooling blood, sharp large intestine.
Flos Sophorae: bitter in the mouth, cold nature.Return liver, lung, the heart, large intestine channel.Cooling blood for hemostasis, liver heat removing and eyesight improving.Discharging fresh blood stool, the hemorrhoid hematochezia, dysentery, hematuria, stranguria with blood, metrorrhagia is spitted blood, epistaxis, liver-heat headache, conjunctival congestion and swelling pain, carbuncle skin infection." the medical center bun is wanted ": it is contrary to let out lung, eliminating heart-fire, clearing away liver-fire, hard kidney water.
The cause of disease of anaphylactoid purpura mostly is heat in blood and stops up the heresy of containing the sense six climate exopathogens of holding concurrently, and pathogenic heat are fought mutually with heat in blood, the absurd row of forcing blood; Or be plain body hyperactivity of fire caused by deficiency of YIN, multiple hinder because of exopathogen or some food, medicine, so that pathogenic heat stop up and hold back venation the absurd row of forcing blood and a speckle.Pathological change is the body of heat in blood, invades excessive space between skin and muscles because of the heresy of wind-fire noxious dampness, gos deep into nutrient blood, and pathogenic heat are fought mutually with heat in blood, the thermal burn channels, and hyperamization liquid does not follow Chang Dao and overflows outside arteries and veins; Or because eating the product of discomfort.It is not normal to cause transporting and transforming function of the spleen and stomach, damp and hot interior giving birth to, and forcing blood is excessive; Or plain body hyperactivity of fire caused by deficiency of YIN, the deficiency of YIN then channels lose to be supported, and hyperactivity of fire then venation is injured, and hyperamization is overflow outside arteries and veins and is fallen ill.In addition, deficiency-weakness of spleen-QI, the insufficiency of the spleen blood of can not uniting, the deficiency of vital energy can not be taken the photograph blood, but also the excessive arteries and veins of hyperamization is sent out speckle outward.Anaphylactoid purpura due to penting up at pyretic toxicity, the traditional Chinese medical science are thought dominance of heat in the interior, and pathogenic heat are gone into nutrient blood, and battalion is cloudy is burnt, then meet red, fever of the body, xerostomia, vexed; Pathogenic heat consumptions is hindered Kidney-Yin, and disturbance nutrient blood outside the blood oozing from the body openings or subcuta neous tissue arteries and veins, and is seen that ecchymosis reveals, or seen epistaxis, bleeding from the gum; Deep red tongue, yellow fur, slippery and rapid pulse are resembling of hyperactivity of toxic heat.
The person of choosing in the side, clearing away heat and cooling blood, detoxifcation dissipating rashes.Gypsum Fibrosum, the Rhizoma Anemarrhenae, Radix Paeoniae Rubra, Cortex Moutan, Rhizoma Coptidis clearing away heat-fire, Radix Rehmanniae clearing away heat and cooling blood, Radix Scrophulariae, Fructus Forsythiae, Fructus Forsythiae removing pathogenic heat from blood and toxic substance from the body, Folium Bambusae clearing heat and relieving fidgetness, Radix Arnebiae (Radix Lithospermi) detoxifcation rash, Flos Sophorae cooling blood for hemostasis.Play altogether full side, clearing away heat and cooling blood, detoxifcation dissipating rashes, balance body negative and positive.Anaphylactoid purpura due to penting up at pyretic toxicity distinguishes that disease executing control, and curative effect is fast, and cost is low, determined curative effect, and prevention effect is remarkable, doublely takes stopgap measures this.
Form of Chinese drug of the present invention can adopt tablet, granule, pill, capsule, solution, oral liquid, buccal tablet, granule, electuary, powder, suspensoid, powder.Preferably, can adopt solution, granule, pill and capsule.
Result of use
50 patients (birth 8-15 year) are used the Chinese medicine for the treatment of anaphylactoid purpura of the present invention, and 1 course for the treatment of of continued treatment (1 month), wherein 19 examples are cured fully, and it is normal that index is recovered; 26 routine remissions; Invalid 5 examples, overall effective percentage reaches 90%, and does not have recurrence.
Example:
The patient 1: grandson, and the male, 11 years old, onset was hurried, and red complexion is red, and skin mucosa has ecchymosis, and is bright-colored, and that touches is scorching hot, bitter taste and dryness in the mouth, thirst with desire to take cold drink, Huang is searched in constipation.Deep red tongue, yellow fur, slippery and rapid pulse.Be anaphylactoid purpura after diagnosing.Take 2 weeks of Chinese medicine of the present invention, red complexion is red to be alleviated, and ecchymosis disappears, and continues two weeks of medication, and other symptoms also all disappear, recovery from illness.Follow up a case by regular visits to after half a year, do not have recurrence.
The patient 2: the Wang, and the women, 9 years old, heating paresthesia appears behind the wind and cold, and ecchymosis in flakes appears subsequently, and with bleeding from the gum, vexed not peaceful.Red tongue with yellow fur, rolling pulse.Doctor trained in Western medicine medication treatment is not felt any better, after take 2 weeks of Chinese medicine of the present invention, ecchymosis disappears, and continues 2 weeks of medication, other symptoms also all disappear, recovery from illness did not have recurrence in 3 months so far.
The patient 3: Hu, the male, 12 years old, purpura was more, the color aquatic foods are not dim, that touches is scorching hot, the time end companion's bleeding from the gum, dimly red tongue when sending out.The back uses Chinese medicine of the present invention to treat, and after 2 weeks, purpura alleviates, and continues 2 weeks of medication, and other symptoms all disappear, and recovery from illness does not have recurrence so far.
The patient 4: Zheng, and the women, 11 years old, anaphylactoid purpura, the color aquatic foods are not dim, protracted course of disease, epistaxis, bitter taste and dryness in the mouth, thirst with desire to take cold drink.Yellow fur, tongue is dim red, rolling pulse.Use Chinese medicine of the present invention to treat, after half course for the treatment of, purpura begins to reduce, and epistaxis disappears, and continues medication and consolidates the course for the treatment of half, and other symptoms also all disappear, and do not have recurrence so far.
The specific embodiment
In order to understand the present invention better, below by embodiment the present invention is described.
Embodiment 1
A kind of Chinese medicine for the treatment of anaphylactoid purpura in weight portion, comprises following component: Gypsum Fibrosum 28-32, Radix Rehmanniae 12-18, Radix Scrophulariae 9-15, Folium Bambusae 7-11, Rhizoma Anemarrhenae 9-15, Radix Paeoniae Rubra 9-15, Cortex Moutan 12-18, Fructus Forsythiae 12-18, Rhizoma Coptidis 2-4, Radix Scutellariae 12-18, Radix Arnebiae (Radix Lithospermi) 12-18, Flos Sophorae 9-15.
Its preparation method is:
In weight portion, get Radix Rehmanniae Preparata 9, Fructus Corni 7, the Cortex Eucommiae 9, Fructus Lycii 7, Semen Cuscutae 9, RHIIZOMA DIOSCOREAE frOm Henan of China 8, Radix Angelicae Sinensis 7, Rhizoma Curcumae 7, Herba Epimedii 8; Above-mentioned Chinese medicine is cleaned, and decontamination is put into container and is added water and do not have medical material to soak, and after 30 minutes, big fire decocts to boiling, and slow fire was endured 1 hour slowly then; Medicine juice is leached, bag distribution packaging, one bag of 200ml sooner or later respectively obeys one bag.
Embodiment 2
A kind of Chinese medicine for the treatment of anaphylactoid purpura in weight portion, comprises following component: Gypsum Fibrosum 28-32, Radix Rehmanniae 12-18, Radix Scrophulariae 9-15, Folium Bambusae 7-11, Rhizoma Anemarrhenae 9-15, Radix Paeoniae Rubra 9-15, Cortex Moutan 12-18, Fructus Forsythiae 12-18, Rhizoma Coptidis 2-4, Radix Scutellariae 12-18, Radix Arnebiae (Radix Lithospermi) 12-18, Flos Sophorae 9-15.
Its preparation method is:
In weight portion, get Radix Rehmanniae Preparata 15, Fructus Corni 11, the Cortex Eucommiae 15, Fructus Lycii 11, Semen Cuscutae 15, RHIIZOMA DIOSCOREAE frOm Henan of China 12, Radix Angelicae Sinensis 11, Rhizoma Curcumae 11, Herba Epimedii 12; Cleaning, drying mix above-mentioned medical material, and per kilogram adds about 10L water, and 0.5-1 at a simmer hour, big fire was fried in shallow oil 1-2 hour; Get decocting liquid and cross 150 mesh sieves, afterwards be concentrated into the clear paste of relative density 1.10-1.20 with concentrator, get 2/3 clear paste 120 ℃ of following spray dryinges, get the clear paste powder, powder is mixed with residue 1/3 clear paste, granulate; The packing of granule racking machine namely gets granule.
Embodiment 3
A kind of Chinese medicine for the treatment of anaphylactoid purpura in weight portion, comprises following component: Gypsum Fibrosum 30, the Radix Rehmanniae 15, Radix Scrophulariae 12, Folium Bambusae 9, the Rhizoma Anemarrhenae 12, Radix Paeoniae Rubra 12, Cortex Moutan 15, Fructus Forsythiae 15, Rhizoma Coptidis 3, Radix Scutellariae 15, Radix Arnebiae (Radix Lithospermi) 15, Flos Sophorae 12.
Its preparation method is:
In weight portion, get Gypsum Fibrosum 30, the Radix Rehmanniae 15, Radix Scrophulariae 12, Folium Bambusae 9, the Rhizoma Anemarrhenae 12, Radix Paeoniae Rubra 12, Cortex Moutan 15, Fructus Forsythiae 15, Rhizoma Coptidis 3, Radix Scutellariae 15, Radix Arnebiae (Radix Lithospermi) 15, Flos Sophorae 12; Cleaning, drying mix above-mentioned medical material, and pulverizing with pulverizer is 150-180 order fine powder, and add suitable Mel and mix, the pellet processing machine pill, cold drying, packing namely gets pill.
Embodiment 4
A kind of Chinese medicine for the treatment of anaphylactoid purpura in weight portion, comprises following component: Gypsum Fibrosum 30, the Radix Rehmanniae 15, Radix Scrophulariae 12, Folium Bambusae 9, the Rhizoma Anemarrhenae 12, Radix Paeoniae Rubra 12, Cortex Moutan 15, Fructus Forsythiae 15, Rhizoma Coptidis 3, Radix Scutellariae 15, Radix Arnebiae (Radix Lithospermi) 15, Flos Sophorae 12.
Its preparation method is:
In weight portion, get Gypsum Fibrosum 30, the Radix Rehmanniae 15, Radix Scrophulariae 12, Folium Bambusae 9, the Rhizoma Anemarrhenae 12, Radix Paeoniae Rubra 12, Cortex Moutan 15, Fructus Forsythiae 15, Rhizoma Coptidis 3, Radix Scutellariae 15, Radix Arnebiae (Radix Lithospermi) 15, Flos Sophorae 12; Cleaning, drying mix above-mentioned medical material, and per kilogram adds about 10L water, and 0.5-1 at a simmer hour, big fire was fried in shallow oil 1-2 hour; Get decocting liquid and cross 150 mesh sieves, afterwards be concentrated into the clear paste of relative density 1.10-1.20 with concentrator, get 2/3 clear paste 120 ℃ of following spray dryinges, get the clear paste powder, powder is mixed with residue 1/3 clear paste, granulate; Granule is made the 0.4g/ capsules with the capsule filler.
Claims (4)
1. a Chinese medicine for the treatment of anaphylactoid purpura is characterized in that, in weight portion, comprises following component: Gypsum Fibrosum 28-32, Radix Rehmanniae 12-18, Radix Scrophulariae 9-15, Folium Bambusae 7-11, Rhizoma Anemarrhenae 9-15, Radix Paeoniae Rubra 9-15, Cortex Moutan 12-18, Fructus Forsythiae 12-18, Rhizoma Coptidis 2-4, Radix Scutellariae 12-18, Radix Arnebiae (Radix Lithospermi) 12-18, Flos Sophorae 9-15.
2. Chinese medicine according to claim 1 is characterized in that, in weight portion, preferably comprises following component: Gypsum Fibrosum 30, the Radix Rehmanniae 15, Radix Scrophulariae 12, Folium Bambusae 9, the Rhizoma Anemarrhenae 12, Radix Paeoniae Rubra 12, Cortex Moutan 15, Fructus Forsythiae 15, Rhizoma Coptidis 3, Radix Scutellariae 15, Radix Arnebiae (Radix Lithospermi) 15, Flos Sophorae 12.
3. Chinese medicine according to claim 1 is characterized in that, described Chinese medicine adopts tablet, granule, pill, capsule, solution, oral liquid, buccal tablet, granule, electuary, powder, suspensoid, powder.
4. Chinese medicine according to claim 1 is characterized in that, described Chinese medicine preferably adopts solution, granule, pill and capsule.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104667020A (en) * | 2015-03-20 | 2015-06-03 | 孙号 | Pharmaceutical composition for treating anaphylactoid purpura and preparation method of pharmaceutical composition |
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| WO2005095412A1 (en) * | 2004-04-01 | 2005-10-13 | Kureha Corporation | Antiallergic agent |
| CN102973819A (en) * | 2011-09-07 | 2013-03-20 | 林凡新 | Traditional Chinese medicine prescription for treatment of allergic purpura |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2005095412A1 (en) * | 2004-04-01 | 2005-10-13 | Kureha Corporation | Antiallergic agent |
| CN102973819A (en) * | 2011-09-07 | 2013-03-20 | 林凡新 | Traditional Chinese medicine prescription for treatment of allergic purpura |
Non-Patent Citations (1)
| Title |
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| CN104667020A (en) * | 2015-03-20 | 2015-06-03 | 孙号 | Pharmaceutical composition for treating anaphylactoid purpura and preparation method of pharmaceutical composition |
| CN104667020B (en) * | 2015-03-20 | 2018-06-05 | 新乡医学院第一附属医院 | A kind of pharmaceutical composition for treating anaphylactoid purpura and preparation method thereof |
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Application publication date: 20130814 |