CN104069463B - A kind of Chinese drugs agentia for treating gynaecologic metrorrhagia - Google Patents

A kind of Chinese drugs agentia for treating gynaecologic metrorrhagia Download PDF

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CN104069463B
CN104069463B CN201410326044.3A CN201410326044A CN104069463B CN 104069463 B CN104069463 B CN 104069463B CN 201410326044 A CN201410326044 A CN 201410326044A CN 104069463 B CN104069463 B CN 104069463B
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仵爱涛
仵典
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Abstract

The present invention provides a kind of Chinese drugs agentia for treating gynaecologic metrorrhagia, it is for treating women because deficiency of Yin sun is fought, cold-evil visitor is in born of the same parents, the pure Chinese medicinal preparation of uterine bleeding caused by dripping urine endlessly, said preparation is mainly by lotus leaf, lotus, fry CedarLeaves, Radix Rhapontici seu Radix Echinopsis, Rhizoma Chuanxiong, steep rhizoma zingiberis, cattail pollen, Radix Codonopsis, osmanthus heart, process radix rehmanniae preparata, Radix Angelicae Sinensis, Radix Paeoniae Alba, Ramulus Taxilli, scouring rush, Plant Soot, it distributes arbituarily, fructus gardeniae, akebi, the 31 taste Chinese herbal medicines such as toast cat placenta are made, on this basis, Tian Ai is supplemented to serious and obstinate patient, Chinese yam, cimicifugae foetidae, radix scutellariae, RADIX POLYGONI MULTIFLORI PREPARATA, decoction or pill made of the 25 taste Chinese herbal medicine such as rhizoma anemarrhenae, inventive formulation is rigorous, science, its short treating period, it is quick, mild in medicine property and, safety.It is 96% for the dripping uterine bleeding cure rate of type not to the utmost of menses, effective percentage 99% is 95% to the sudden and violent mo(u)ld bottom half uterine bleeding cure rate of menses, and effective percentage is 97%, and the uterine bleeding patient's cure rate for having type concurrently to the two is 93%, and effective percentage is 95%.

Description

A kind of Chinese drugs agentia for treating gynaecologic metrorrhagia
Technical field
The present invention relates to the field of Chinese medicines, be with one kind for treat women because deficiency of Yin sun fights, cold-evil visitor in born of the same parents, it is dripping not Uterine bleeding caused by breaking, through row distending pain, long through more than Chinese drugs agentia, it is soothing the liver can also to carry out regulating the qi flowing in the channels to most patients.
Background technology
Uterine bleeding is the common disease of gynaecology, frequently-occurring disease, and women not between menstrual period or during passing through bleed profusely suddenly by vagina, Or the dripping continuous person of lower blood referred to as " uterine bleeding " if menostaxis up to two weeks or more persons, should belong to uterine bleeding scope.General unexpected bleeding, The oncoming force is anxious, and crying more than blood volume is collapsed;Dripping lower blood, the oncoming force are slow, blood volume it is few cry leakage, some Chinese medicine, which is also cried, long passes through more than, menses not Only;Though collapse from leakage bleeding it is different, its pathogenesis is consistent, and in disease progression often mutually turn Change, the functional uterine bleeding of doctor trained in Western medicine, female sex organ inflammation, cervix tumor, drug administration(Such as endocrine preparation)Equal institutes The colporrhagia of appearance, all belongs to uterine bleeding scope, and uterine bleeding is more difficult, complexity a symptom in woman in menstrual period disease.In Chinese medicine Apparently, there are much relations in born of the same parents with cold-evil hot gas visitor the main reason for uterine bleeding.Currently, treatment with western uterine bleeding, general to use Estrogen controls that agent, progesterone, hemostat etc. be single or united cycle therapy, and still, curative effect is less notable, and patient is to controlling The Western medicine for treating uterine bleeding is also easy to produce dependence, and the state of an illness easily occurs repeatedly after drug withdrawal, and Western medicine directly acts on internal organ for a long time, easily gives people Body brings side effect, the patient of the more than serious symptom of doctor trained in Western medicine operative treatment menses to mostly use the palace of the Qing Dynasty, uterectomy scheme, still The palace of the Qing Dynasty, uterectomy therapy certain negative effect can be generated to Liver And Spleen of Patients kidney, cause toxin cannot(Completely)Row It removes, moreover, operation has certain wound, easily causes multiple complications.
Chinese medicine thinks that through water, for liver and spleen kidney, blood cannot reconcile, it is indicated that menses are more than related with liver and spleen kidney stomach.Therefore Chinese medicine Using regulating blood method.All to improve blood system, the method to treat blood system disease is referred to as regulating blood method, and this law has conditioning blood system, The effects that promoting blood, dissipation hemostasis and prevention bleeding.Blood is the important substance of nutrition human body, blood fortune it is normal then in can be perfused it is dirty Internal organs passages through which vital energy circulates, outside can nutrition four limbs bones of the body collectively, therefore《Hardly possible warp.22 is difficult》Meaning:" blood nourishing " supports the meaning of whole body.If blood system By disease, then internal organs passages through which vital energy circulates, which loses, supports, to become raw all kinds of blood trouble.Blood disease is divided into actual situation fever and chills, has hemostasis, loses blood different, but returns For receiving, always nothing more than the deficiency of blood, blood stasis, bleeding three types.Therefore regulating blood condition method, can divide enrich blood, invigorate blood circulation, three sides of stopping blooding Face.According to " heart governing blood and vessels ", the theory of " blood stored in the liver ", " spleen green blood ", mostly and the heart, liver, spleen three is dirty related, so adjusting for blood system disease Regulating blood condition point, also mostly from the heart, liver, spleen three is dirty sets about.
Lack a kind of prescription of simple and easy to do treatment uterine bleeding on the market at present, i.e. symptomatic treatment in acute condition, radical treatment in chronic case or sample is simultaneous It controls.Therefore dialectical formula combination is carried out for the more than pathogenesis of menses according to theory of traditional Chinese medical science, so as to patient according to symptom from Oneself increase and decrease dosage is eliminated ailing.
Invention content
To overcome the shortcomings of that Western medicine drug, operative treatment, the present invention are directed to the pathogenesis of uterine bleeding, carry out dialectical formula group Close, provide a kind of effective treatment because deficiency of Yin sun fights, uterine bleeding of the cold-evil visitor in born of the same parents, caused by dripping urine endlessly, through row distending pain, menses not Chinese medicine preparation only, it has significant in efficacy, short treating period, a symptomatic treatment in acute condition, radical treatment in chronic case and treating both manifestation and root cause of disease, it is safe and reliable, without pair The characteristics of effect, pharmacist can increase and decrease dosage according to patient symptom and eliminate patient's slight illness.
The technical solution adopted by the present invention is:Component including following parts by weight is prepared:10-40 parts of lotus leaf, lotus 10-40 parts, 15-30 parts of the garden burnet of micro- stir-fry fries 10-30 parts of CedarLeaves, 10-30 parts of Radix Rhapontici seu Radix Echinopsis, 10-30 parts of Rhizoma Chuanxiong, bubble rhizoma zingiberis 10-30 Part, 6-20 parts of cattail pollen, 10-30 parts of Radix Codonopsis, 9-30 parts of osmanthus heart, 10-30 parts of Radix Paeoniae Alba process 20-30 parts of radix rehmanniae preparata, and 15-30 parts of Radix Angelicae Sinensis is sweet 3-8 parts careless, 12-30 parts of PORIA ALBA pulverizes 10-40 parts of the deer horn glue of stir-bake to yellowish, and 15-40 parts of humus flava usta, 10-30 parts of rhizoma cyperi, mulberry is posted Raw 10-30 parts, 6-20 parts of scouring rush, 10-40 parts of Plant Soot distributes 6-20 parts arbituarily, 9-30 parts of fructus gardeniae, 10-15 parts of akebi, Chinese cassia tree 20-30 parts, 40-60 parts of boys' urine rhizoma cyperi, 20-50 parts of cuttle bone, 15-40 parts of Rhizoma Atractylodis Macrocephalae, 10-30 parts of radix cynanchi atrati, toast cat placenta 10-30 Part, rotate 20-30 parts of prince ' s-feather.
One of preferred embodiment as the present invention:Component including following parts by weight is prepared:30 grams of lotus leaf, lotus 30 grams, 15 grams of the garden burnet of micro- stir-fry fries 12 grams of CedarLeaves, 15 grams of Radix Rhapontici seu Radix Echinopsis, and 15 grams of Rhizoma Chuanxiong steeps 12 grams of rhizoma zingiberis, 10 grams of cattail pollen, Radix Codonopsis 20 Gram, 12 grams of osmanthus heart, 15 grams of Radix Paeoniae Alba processs 20 grams of radix rehmanniae preparata, and 20 grams of Radix Angelicae Sinensis, 8 grams of Radix Glycyrrhizae, 15 grams of PORIA ALBA pulverizes the deer horn glue of stir-bake to yellowish 15 grams, 30 grams of humus flava usta, 20 grams of rhizoma cyperi, 15 grams of Ramulus Taxilli, 15 grams of scouring rush, 15 grams of Plant Soot distributes 9 grams arbituarily, 12 grams of fructus gardeniae, wood It is 12 grams logical, 20 grams of Chinese cassia tree, 40 grams of boys' urine rhizoma cyperi, 20 grams of cuttle bone, 15 grams of Rhizoma Atractylodis Macrocephalae, 12 grams of radix cynanchi atrati, 15 grams of toast cat placenta, rotation water 20 grams of safflower.
For very critical or cureless patient, the present invention increases some Chinese medicine groups on the basis of original prescription Part, with stiffening effect, as the two of preferred embodiment of the invention, the present invention still further comprises the Chinese medicine group of following parts by weight Point:Field ends 15-40 parts, 10-30 parts of Chinese yam, 9-20 parts of cimicifugae foetidae, 10-25 parts of radix scutellariae, 20-60 parts of dried orange peel, 10-15 parts of radix bupleuri, benefit 20-60 parts of Brittle Falsepimpernel Herb, 15-20 parts of Radix Astragali, river connect 12-15 parts, 20-60 parts of oyster, 10-20 parts of Cortex Phellodendri, 15-60 parts of hawthorn, and system is first It is 20-60 parts black, 15-20 parts of rhizoma anemarrhenae, 10-20 parts of Divine Comedy, 10-20 parts of radix scrophulariae, 10-20 parts of red ginseng, 12-25 parts of peach kernel, cockscomb 20-60 parts, 10-15 parts of red raspberry, 10-25 parts of brush-cherry seed, 20-40 parts of oriental wormwood, 10-30 parts of frutus cnidii, 20-60 parts of amethyst, 15-20 parts of angelica tail.
Three as preferred embodiment of the invention:The present invention still further comprises the traditional Chinese medicinal components of following parts by weight:Tian Ai 30 grams, 20 grams of Chinese yam, 15 grams of cimicifugae foetidae, 12 grams of radix scutellariae, 20 grams of dried orange peel, 15 grams of radix bupleuri, 30 grams of motherwort, 15 grams of Radix Astragali, river connects 15 Gram, 30 grams of oyster, 15 grams of Cortex Phellodendri, 20 grams of hawthorn, 30 grams of RADIX POLYGONI MULTIFLORI PREPARATA, 20 grams of rhizoma anemarrhenae, 20 grams of Divine Comedy, 20 grams of radix scrophulariae, 15 grams of red ginseng, 12 grams of peach kernel, 30 grams of cockscomb, 12 grams of red raspberry, 12 grams of brush-cherry seed, 30 grams of oriental wormwood, 12 grams of frutus cnidii, 30 grams of amethyst, angelica tail 15 grams.
Four as preferred embodiment of the invention:The dosage form of the present invention is decoction or pill.
The pharmacology of each traditional Chinese medicinal components and preferred concocting process are described as follows in the present invention:
Lotus leaf:Bitter, mild-natured, cooling blood and hemostasis dissipate blood stasis, are chiefly used in bleeding caused by blood-head;
Lotus:Cold in nature, anti-inflammatory relieves the pain;
Garden burnet(Micro- stir-fry):Garden burnet is fried into carbon block shape with slow boiling, spy holds the coke that avales, hemostasis;
Fry CedarLeaves:It is faint yellow that CedarLeaves, which are fried, fries CedarLeaves hardship warm nature and trembles with fear, cooling blood and hemostasis, and purify the blood a point heat;
Radix Rhapontici seu Radix Echinopsis:Bitter is cold in nature, detumescence and apocenosis;
Rhizoma Chuanxiong:Acrid flavour, warm-natured, Wen Nengtong, it is pungent to dissipate;
Steep rhizoma zingiberis:The rhizoma zingiberis being soaked in water, acrid flavour, property heat, there is solution dispersing wind and cold and middle benefit gas Hui Yang;
Cattail pollen:It is sweet in flavor, mild-natured, it can dispersing blood stasis blood;
Radix Codonopsis:It is bitter, it reinforces vital energy;
Osmanthus heart:It is pungent sweet warm-natured, release fleshy exterior and chill;
Radix Paeoniae Alba:It is bitter, cold in nature, there are convergence and replenishing the vital essence and the blood;
Process radix rehmanniae preparata:It is cooled after being made popular together with radix rehmanniae preparata with a small amount of rice vinegar, warm-natured, kidney nourishing and blood enriching;
Radix Angelicae Sinensis:Gan Wen, green blood, bushing, empty, benefit damage is comforted;
Radix Glycyrrhizae:Property is pungent sweet, there is reconciliation effect;
PORIA ALBA:It is sweet light mild-natured, it can sharp water wet down;
Deer horn glue(It is broken, stir-bake to yellowish):Bitter acid it is micro- salty, have the effect of clearing heat and detoxicating, deer horn glue is first pulverized for fritter, small Grain, then fry yellowly.
Humus flava usta:Property heat sweet in flavor, wet liver and gall the spleen channel;
Rhizoma cyperi:Pungent cold in nature have qi-regulating to dissipate the stasis of blood;
Ramulus Taxilli:Bitterness is flat, there is the function of strengthening the bones and muscles kidney tonifying;
Scouring rush:Sweetness and bitterness is mild-natured, there is hemostasia and dissipation blood stasis effect;
Plant Soot:It is acrid flavour, warm-natured, mainly there is anastalsis;
It distributes arbituarily;Bitter, slightly warm in nature, tonifying yin effect are very big;
Fructus gardeniae:Bitter is cold in nature, can cooling blood and hemostasis;
Akebi:It is bitter, cold in nature, there are heat-clearing and diuresis function;
Chinese cassia tree:Acrid-sweet flavor, extremely hot in nature have the effect of yang-tonifying cold dispelling, analgesic;
Boys' urine rhizoma cyperi:Child refers to:3 years old or less and the boy are the first tires in family, impregnate rhizoma cyperi one using the urine of the boy Week is anti-inflammatory, promoting blood circulation and removing blood stasis better to get boys' urine rhizoma cyperi.
Cuttle bone:It is warm-natured, there is the effect of tonneau urine;
Rhizoma Atractylodis Macrocephalae:Bitter, warm-natured, strengthening the spleen and replenishing qi, eliminate dampness and have diuretic effect;
Radix cynanchi atrati:Bitterness is cold, most can removing summer-heat blood system heat evil;
Process cat placenta:Cat placenta is heated in vessel after drying to obtain the final product, it is warm-natured, it reinforces vital energy;
Rotate prince ' s-feather:Finger is grown in the prince ' s-feather that flow is suddenly located, and prince ' s-feather seems to be in " rotation " shape, it is cold in nature, living Blood stagnation resolvation, the more common prince ' s-feather of hemostasis drug effect are more preferable;
Tian Ai:It is bitter, warm-natured, there is the function of warming meridian and hemostasis and pain-relieving;
Chinese yam:It is sweet in flavor, mild-natured, strengthening the spleen and tonifying the lung, beneficial stomach kidney tonifying;
Cimicifugae foetidae:It is sweet in flavor, it is cold in nature, it is clearing heat and detoxicating, it rises and lifts yang-energy;
Radix scutellariae:Bitter cold, reducing liver heat, clearing lung-heat heat;
Dried orange peel:Pungent-warm, qi-regulating, stomach invigorating;
Radix bupleuri:Bitter, be slightly cold, can purge the green and reducing fever by reconciliation;
Motherwort:Warm-natured, leukorrhea is gone in smelling removal;
Radix Astragali:It is bitter, cold in nature, there is heat-clearing and damp-drying drug;
River connects:Bitter cold, clearing away the heart-fire, cold-dispelling;
Oyster:Taste is salty, cold nature, there is wet smart hidroschesis;
Cortex Phellodendri:Bitter cold has warm cloudy fall fire;
Hawthorn:Sour sweet, stomach invigorating;
RADIX POLYGONI MULTIFLORI PREPARATA:The fleece-flower root is steamed with white wine, the fleece-flower root is steamed thoroughly, other Powder Made by Steamed Method can also be used or cooks method, it is warm-natured, The strong the moon of yang-tonifying;
Rhizoma anemarrhenae:Gan Han, invigorating the spleen;
Divine Comedy:Acrid flavour stomach invigorating;
Radix scrophulariae:It is warm-natured, it clears liver and improve vision;
Red ginseng:Gan Wen, bowl spares gas;
Peach kernel:Bitter sweet is mild-natured, there is moisturize laxation effect;
Cockscomb:Xin Han, dissipate stasis of blood hemostasis;
Red raspberry:Bitter cold detoxifies and dissipates the stasis of blood;
Brush-cherry seed:Warm-natured, Gan Han, profit liver lung fills blood;
Oriental wormwood:Bitter cold, removing jaundice heat-clearing;
Frutus cnidii:It is warm-natured, expelling wind and clearing away cold;
Angelica tail:Gan Xing, temperature compensation and blood;
Amethyst:It is cold in nature, calmness removing toxic substances;
Chinese drugs agentia of the present invention is under Traditional Chinese medical theory and clinical experience guidance, and to adjust liver and spleen, mild taste are The rules for the treatment of, selected medicament composing prescription, treating both manifestation and root cause of disease.The selected medicament composing prescription of the present invention complements each other through dialectical compatibility using, energy Enough achieve the purpose that healing.
Substantially square prescription mechanism is:Lotus leaf, lotus, the garden burnet of micro- stir-fry, Rhizoma Chuanxiong steep rhizoma zingiberis, cattail pollen, Radix Codonopsis, osmanthus heart master It is used for metrorrhagia caused by blood-head, can to subside a swelling hemostasis;Radix Rhapontici seu Radix Echinopsis is cold in nature, clearing heat and detoxicating, detumescence and promoting granulation, fries CedarLeaves cold nature, has cool Blood, hemostasis purify the blood the effect of point damp and hot, and two medicine compatibilities can enhance the drug effect of clearing heat for detumescence hemostasis;Radix Paeoniae Alba, toast radix rehmanniae preparata, Radix Angelicae Sinensis, PORIA ALBA, the deer horn glue of stir-bake to yellowish, humus flava usta, rhizoma cyperi, Ramulus Taxilli, scouring rush's temperature liver kidney tonifying, rising Yang dissipate fire, bowl spares gas, scattered blood stasis;It is sweet Grass is sweet in flavor mild-natured, and all pharmacological property is adjusted, living to solve various pharmacological property toxicity;Plant Soot is distributed arbituarily, fructus gardeniae, akebi, Chinese cassia tree, and boys' urine is fragrant Attached, cuttle bone, Rhizoma Atractylodis Macrocephalae, radix cynanchi atrati processs cat placenta, rotates prince ' s-feather establishing-Yang promoting menstruation, and strengthening spleen, tonifying kidney, stomach invigorating temperature liver makes negative and positive align, Qi and blood balances, blood returns spleen stomach, and menses are normal.
Preferably, for the state of an illness is critical or the prescription mechanism of the medicament of obstinate patient is:Lotus leaf, lotus, garden burnet, river Rhizome of chuanxiong, bubble rhizoma zingiberis, cattail pollen, Radix Codonopsis, osmanthus heart are mainly used for clearing liver dampness removing, warm spleen kidney tonifying, promoting blood circulation to remove blood stasis;Radix scutellariae, river are even mainly used for Clearing away heart-fire detoxification;Tian Ai, Chinese yam, cimicifugae foetidae, dried orange peel, Radix Astragali, oyster, Cortex Phellodendri, hawthorn, the pleasant qi-regulating of RADIX POLYGONI MULTIFLORI PREPARATA, promoting blood circulation and removing blood stasis, tonifying spleen Rising Yang;Rhizoma anemarrhenae, Divine Comedy, radix scrophulariae, peach kernel, cockscomb, all medicine pharmacological property of amethyst is steady, can calm warm kidney, stomach invigorating promoting blood circulation, warm liver mends Spleen;Radix Angelicae Sinensis is mainly used for blood circulation promoting and enriching;The pleasant scattered stasis of blood of boys' urine rhizoma cyperi;Rhizoma Atractylodis Macrocephalae tonifying spleen and stomach eliminating dampness;The two compatibility enhances stagnation resolvation of enriching blood Promoting the circulation of qi effect;Red raspberry, brush-cherry seed, oriental wormwood, frutus cnidii, angelica tail, red ginseng are used for warm liver tonifying Qi, promote blood circulation, make blood Passages through which vital energy circulates is fully recovered as early as possible;Lotus leaf clearing away heat to stop bleeding priming enters liver, and enhances PORIA ALBA, deer horn glue, humus flava usta, boys' urine rhizoma cyperi, Ramulus Taxilli, The benefits of scouring rush, Plant Soot are distributed arbituarily, cape jasmine, radix bupleuri, and motherwort gives birth to new blood and dissolving stasis, qi and blood balance, rebuilds one's physical constitution;Fry CedarLeaves, leakage Reed, Radix Paeoniae Alba, rhizoma cyperi, moxibustion radix rehmanniae preparata, akebi, Chinese cassia tree invigorating the spleen promoting blood circulation, ascending YANG and invigorating QI;Cuttle bone, radix cynanchi atrati process cat placenta, and rotation is bright pink Flower nourishing yin and lessening fire is promoting blood circulation and removing blood stasis;Radix Glycyrrhizae is that reconciliation flavour of a drug reduce drug toxicity, and all medicine cooperations complement each other, play altogether, dissipate the stasis of blood and live Blood, the work(that clearing heat and detoxicating hemostasis promoting the circulation of qi clearing liver warm kidney qi-regulating is promoted blood circulation.
Pharmaceutical formulation of the present invention is rigorous, science, is to be discussed by Chinese medicine pharmacology, prescription, in conjunction with ancient times, modern clinic scientific research prescription Made of pure Chinese medicinal preparation, configuration is easy, medicine source is wide, at low cost, verifies by clinic application, and the present invention treats uterine bleeding clinic and treats Effect significantly, short treating period, quick, treating both manifestation and root cause of disease is uneasy to recur, mild in medicine property and, safety, do not find toxic side effect.The present invention has There is substantially square, supplement side, it is organic through exclusion according to clinical statistics for many years with for the different patient of severe extent The factors such as lesion, for the effective percentage 99% of the dripping uterine bleeding of type not to the utmost of general menses, cure rate 96%, under sudden and violent to menses Type uterine bleeding, cure rate 95%, effective percentage are 97%, and the uterine bleeding patient's cure rate for having type concurrently to the two is 93%, and effective percentage is 95%. In addition, the present invention also has fine curative effect, specific Cure to regard such disease uterine bleeding caused by the organic diseases such as palace tumor Depending on disease concrete condition.
Specific implementation mode
With reference to embodiment, the invention will be further described:
Embodiment 1:The Chinese drugs agentia includes that the component of following parts by weight is prepared:10 grams of lotus leaf, 10 grams of lotus, micro- stir-fry 15 grams of garden burnet, fry 10 grams of CedarLeaves, 10 grams of Radix Rhapontici seu Radix Echinopsis, 10 grams of Rhizoma Chuanxiong, steep 10 grams of rhizoma zingiberis, 6 grams of cattail pollen, 10 grams of Radix Codonopsis, 9 grams of osmanthus heart, 10 grams of Radix Paeoniae Alba, 20 grams of radix rehmanniae preparata of toast, 15 grams of Radix Angelicae Sinensis, 3 grams of Radix Glycyrrhizae, 12 grams of PORIA ALBA pulverize 10 grams of the deer horn glue of stir-bake to yellowish, humus flava usta 15 Gram, 10 grams of rhizoma cyperi, 10 grams of Ramulus Taxilli, 6 grams of scouring rush, 10 grams of Plant Soot distributes 6 grams arbituarily, 9 grams of fructus gardeniae, 10 grams of akebi, Chinese cassia tree 20 Gram, 40 grams of boys' urine rhizoma cyperi, 20 grams of cuttle bone, 15 grams of Rhizoma Atractylodis Macrocephalae, 10 grams of radix cynanchi atrati, 10 grams of toast cat placenta, 20 grams of prince ' s-feather of rotation.
Embodiment 2:The Chinese drugs agentia includes that the component of following parts by weight is prepared:40 grams of lotus leaf, 40 grams of lotus, micro- stir-fry 30 grams of garden burnet, fry 30 grams of CedarLeaves, 30 grams of Radix Rhapontici seu Radix Echinopsis, 30 grams of Rhizoma Chuanxiong, steep 30 grams of rhizoma zingiberis, 20 grams of cattail pollen, 30 grams of Radix Codonopsis, osmanthus heart 30 Gram, 30 grams of Radix Paeoniae Alba processs 30 grams of radix rehmanniae preparata, and 30 grams of Radix Angelicae Sinensis, 8 grams of Radix Glycyrrhizae, 30 grams of PORIA ALBA pulverizes 40 grams of the deer horn glue of stir-bake to yellowish, Fu Long 40 grams of liver, 30 grams of rhizoma cyperi, 30 grams of Ramulus Taxilli, 20 grams of scouring rush, 40 grams of Plant Soot distribute 20 grams arbituarily, 30 grams of fructus gardeniae, 15 grams of akebi, 30 grams of Chinese cassia tree, 60 grams of boys' urine rhizoma cyperi, 50 grams of cuttle bone, 40 grams of Rhizoma Atractylodis Macrocephalae, 30 grams of radix cynanchi atrati, 30 grams of toast cat placenta rotate prince ' s-feather 30 Gram.
Embodiment 3:The Chinese drugs agentia is made of the component of following parts by weight:
30 grams of lotus leaf, 30 grams of lotus, 15 grams of the garden burnet of micro- stir-fry fry 12 grams of CedarLeaves, 15 grams of Radix Rhapontici seu Radix Echinopsis, and 15 grams of Rhizoma Chuanxiong steeps rhizoma zingiberis 12 grams, 10 grams of cattail pollen, 20 grams of Radix Codonopsis, 12 grams of osmanthus heart, 15 grams of Radix Paeoniae Alba, 20 grams of radix rehmanniae preparata of toast, 20 grams of Radix Angelicae Sinensis, 8 grams of Radix Glycyrrhizae, PORIA ALBA 15 grams, pulverize 15 grams of the deer horn glue of stir-bake to yellowish, 30 grams of humus flava usta, 20 grams of rhizoma cyperi, 15 grams of Ramulus Taxilli, 15 grams of scouring rush, 15 grams of Plant Soot, Distribute 9 grams arbituarily, 12 grams of fructus gardeniae, 12 grams of akebi, 20 grams of Chinese cassia tree, 40 grams of boys' urine rhizoma cyperi, 20 grams of cuttle bone, 15 grams of Rhizoma Atractylodis Macrocephalae, radix cynanchi atrati 12 Gram, 15 grams of toast cat placenta rotates 20 grams of prince ' s-feather.
Embodiment 4:The Chinese drugs agentia is made of the component of following parts by weight:
10 grams of lotus leaf, 10 grams of lotus, 15 grams of the garden burnet of micro- stir-fry fry 10 grams of CedarLeaves, 10 grams of Radix Rhapontici seu Radix Echinopsis, and 10 grams of Rhizoma Chuanxiong steeps rhizoma zingiberis 10 grams, 6 grams of cattail pollen, 10 grams of Radix Codonopsis, 9 grams of osmanthus heart, 10 grams of Radix Paeoniae Alba, 20 grams of radix rehmanniae preparata of toast, 15 grams of Radix Angelicae Sinensis, 3 grams of Radix Glycyrrhizae, PORIA ALBA 12 Gram, pulverize 10 grams of the deer horn glue of stir-bake to yellowish, 15 grams of humus flava usta, 10 grams of rhizoma cyperi, 10 grams of Ramulus Taxilli, 6 grams of scouring rush, 10 grams of Plant Soot, unrest 6 grams of hair, 9 grams of fructus gardeniae, 10 grams of akebi, 20 grams of Chinese cassia tree, 40 grams of boys' urine rhizoma cyperi, 20 grams of cuttle bone, 15 grams of Rhizoma Atractylodis Macrocephalae, 10 grams of radix cynanchi atrati, 10 grams of cat placenta is processed, 20 grams of prince ' s-feather is rotated;
Field ends 15 grams, 10 grams of Chinese yam, 9 grams of cimicifugae foetidae, 10 grams of radix scutellariae, 20 grams of dried orange peel, 10 grams of radix bupleuri, 20 grams of motherwort, Radix Astragali 15 grams, river connects 12 grams, 20 grams of oyster, 10 grams of Cortex Phellodendri, 15 grams of hawthorn, 20 grams of RADIX POLYGONI MULTIFLORI PREPARATA, 15 grams of rhizoma anemarrhenae, 10 grams of Divine Comedy, radix scrophulariae 10 Gram, 10 grams of red ginseng, 12 grams of peach kernel, 20 grams of cockscomb, 10 grams of red raspberry, 10 grams of brush-cherry seed, 20 grams of oriental wormwood, 10 grams of frutus cnidii, purple 20 grams of quartz, 15 grams of angelica tail.
Embodiment 5:The Chinese drugs agentia is made of the component of following parts by weight:
40 grams of lotus leaf, 40 grams of lotus, 30 grams of the garden burnet of micro- stir-fry fry 30 grams of CedarLeaves, 30 grams of Radix Rhapontici seu Radix Echinopsis, and 30 grams of Rhizoma Chuanxiong steeps rhizoma zingiberis 30 grams, 20 grams of cattail pollen, 30 grams of Radix Codonopsis, 30 grams of osmanthus heart, 30 grams of Radix Paeoniae Alba, 30 grams of radix rehmanniae preparata of toast, 30 grams of Radix Angelicae Sinensis, 8 grams of Radix Glycyrrhizae, white Fu 30 grams of Siberian cocklebur pulverizes 40 grams of the deer horn glue of stir-bake to yellowish, 40 grams of humus flava usta, 30 grams of rhizoma cyperi, 30 grams of Ramulus Taxilli, 20 grams of scouring rush, Plant Soot 40 Gram, distribute 20 grams arbituarily, 30 grams of fructus gardeniae, 15 grams of akebi, 30 grams of Chinese cassia tree, 60 grams of boys' urine rhizoma cyperi, 50 grams of cuttle bone, 40 grams of Rhizoma Atractylodis Macrocephalae, in vain 30 grams of common vetch, 30 grams of toast cat placenta, rotates 30 grams of prince ' s-feather;
Field ends 40 grams, 30 grams of Chinese yam, 20 grams of cimicifugae foetidae, 25 grams of radix scutellariae, 60 grams of dried orange peel, 15 grams of radix bupleuri, 60 grams of motherwort, Radix Astragali 20 grams, river connects 15 grams, 60 grams of oyster, 20 grams of Cortex Phellodendri, 60 grams of hawthorn, 60 grams of RADIX POLYGONI MULTIFLORI PREPARATA, 20 grams of rhizoma anemarrhenae, 20 grams of Divine Comedy, radix scrophulariae 20 Gram, 20 grams of red ginseng, 25 grams of peach kernel, 60 grams of cockscomb, 15 grams of red raspberry, 25 grams of brush-cherry seed, 40 grams of oriental wormwood, 30 grams of frutus cnidii, purple 60 grams of quartz, 20 grams of angelica tail.
Embodiment 6:The Chinese drugs agentia is made of the component of following parts by weight:30 grams of lotus leaf, 30 grams of lotus, the ground of micro- stir-fry 15 grams of elm, fries 12 grams of CedarLeaves, 15 grams of Radix Rhapontici seu Radix Echinopsis, and 15 grams of Rhizoma Chuanxiong steeps 12 grams of rhizoma zingiberis, 10 grams of cattail pollen, 20 grams of Radix Codonopsis, osmanthus heart 12 Gram, 15 grams of Radix Paeoniae Alba processs 20 grams of radix rehmanniae preparata, and 20 grams of Radix Angelicae Sinensis, 8 grams of Radix Glycyrrhizae, 15 grams of PORIA ALBA pulverizes 15 grams of the deer horn glue of stir-bake to yellowish, 30 grams of humus flava usta, 20 grams of rhizoma cyperi, 15 grams of Ramulus Taxilli, 15 grams of scouring rush, 15 grams of Plant Soot distribute 9 grams arbituarily, 12 grams of fructus gardeniae, akebi 12 Gram, 20 grams of Chinese cassia tree, 40 grams of boys' urine rhizoma cyperi, 20 grams of cuttle bone, 15 grams of Rhizoma Atractylodis Macrocephalae, 12 grams of radix cynanchi atrati, 15 grams of toast cat placenta, rotation prince ' s-feather 20 grams;
Field ends 30 grams, 20 grams of Chinese yam, 15 grams of cimicifugae foetidae, 12 grams of radix scutellariae, 20 grams of dried orange peel, 15 grams of radix bupleuri, 30 grams of motherwort, Radix Astragali 15 grams, river connects 15 grams, 30 grams of oyster, 15 grams of Cortex Phellodendri, 20 grams of hawthorn, 30 grams of RADIX POLYGONI MULTIFLORI PREPARATA, 20 grams of rhizoma anemarrhenae, 20 grams of Divine Comedy, radix scrophulariae 20 Gram, 15 grams of red ginseng, 12 grams of peach kernel, 30 grams of cockscomb, 12 grams of red raspberry, 12 grams of brush-cherry seed, 30 grams of oriental wormwood, 12 grams of frutus cnidii, purple 30 grams of quartz, 15 grams of angelica tail.
By taking embodiment 3 as an example, production method is:
(1)Decoction processing method:Embodiment 3 is dose, by 3 each component of embodiment being decocted in water for oral dose routinely, specific method It is as follows:Each Chinese medicine material in prescription is put into marmite, cold water is added and covers powder, impregnates 15-20 minutes, adds water no mistake 5 centimetres or so of powder is eventually adding three pieces fresh ginger, and three big jujube is to introduce row to decoct, and is cooked by slow fire 45 minutes or so, filters It removes slag, obtains liquid.
(2)Pill processing method is summarized as:Main ingredient is combined together, face is ground into, ball, machine operation is made in water.Specifically Processing method and the method for existing middle liquid medicine pill are essentially identical, and I will not elaborate.Chinese medicine medicine in embodiment in the present invention Pill is processed into agent, three times a day, each 10-15 grams, is sent down with plain boiled water, curative effect is as decoction.
For the manufacturing method of above-described embodiment 1,2,4,5,6 with the manufacturing method of embodiment 3, embodiment 6 is dose.
The dosage form of the present invention further includes the concentrated oral liquid prepared using general technology method.
Beneficial effects of the present invention are proven by following a large amount of clinical test:
(1)Case selection:All 570 cases are trouble of in January, the 2008~2014 year June to here outpatient clinic Person.Wherein, it is dripping not to the utmost, blood gesture not as good as the uterine bleeding case 210 that metrorrhagia is violent, amount of bleeding is less, under menses are sudden and violent, the oncoming force it is anxious, Ferociousness, cannot be from uterine bleeding patient 160 only, and both above-mentioned symptoms have concurrently(It is alternately present)Patient 200,570 cases Age:It is 18~50 years old, 34 years old average.The course of disease:2 days -1.5 years, and meet case exclusion criteria.
Case exclusion criteria:1, it confirms on inspection by gestation, upper ring, wound, systemic bleeding disease, reproductive organs tumour Etc. organic diseases and causer;2, there is allergic constitution or have allergies person.570 are the cases obtained after exclusion.
(2) case diagnosis standard:According to " the disease of tcm Standardization of diagnosis and curative effect " of national Department of Health's publication in 1994 into Row diagnosis.The mark defines 35 kinds of illnesss of gynaecology, wherein the cured Illnesses Diagnoses of the invention according to for the standard chapter 7 " in 10th trifle of doctor gynaecology disease Standardization of diagnosis and curative effect ", i.e. 10.1 diagnosis basis(Menses no periodic can follow;Through amount or it is sudden and violent under such as Note etc.).Further accordance with《Synopsis of Treating Women's Diseases》Chapter 3 the 1st, 2 section, uterine bleeding because spleen injury, abnormal heat cause, diagnosis basis be summarized as through Blood is neglected as under sudden and violent, or even dusk is bored;Dripping urine endlessly, leukorrhea have stench;Low Back Pain or underbelly pain, four limbs are tired, and in combination The prestige of doctor is heard, asks, cutting into the comprehensive dialectical deficiency of Yin sun that meets of row and fight, cold-evil visitor's caused uterine bleeding disease in born of the same parents.
(3)Efficacy assessment standard:
It cures:Restore normal through amount, menstrual period, through color, period, 3 more than the menstrual cycle can be maintained.Or climacteric women blood Only menopause person.Various underbelly pains, dusk is bored, and tired symptom disappears.
Effectively:Though restoring normal through amount, menstrual period, period, 3 menstrual cycles cannot be maintained.Or through amount reduction or menstrual period Shorten.It is changed through color but without restoring to normal color, various underbelly pain, dusk is bored, tired symptom mitigates.
It is not cured:Menstrual cycle, through amount, through color, colporrhagia is unchanged.Various underbelly pain, dusk is bored, and tired symptom is without good Turn sign.
(4)Therapeutic scheme:It treats uterine bleeding and mainly uses 3 decoction of embodiment, a small number of severe patients(No more than patient populations 10%)Or obstinate patient uses 6 decoction of embodiment, pharmacist in the treatment, according to patient body situation, recovery extent, to allow Medicament is adjusted in right amount.
Instructions of taking:One dose per day(900 milliliters or so decoction of medicinal ingredients), it is one three times a day, be divided into early, middle and late take.
Take taboo:1, quit smoking, wine and maror.2, serious conditions person should take in the case where doctor instructs.
(5)Statistical procedures:According to above-mentioned therapeutic scheme, to it is dripping not to the utmost, amount of bleeding it is less, blood gesture is violent not as good as metrorrhagia Uterine bleeding patient 210, treated, take medicine 3-21 days, healing 201, effective 208;Under sudden and violent to menses, break with tremendous force, It cannot treat, take medicine 20-60 days from uterine bleeding patient 160 only, cure 247, effective 252;The two is had concurrently(Through Under blood is sudden and violent, dripping it is alternately present both not to the utmost)200 cases of patient are treated, and are taken medicine 20-40 days, cure 186, effectively 190.
Patient has no adverse reaction during treatment, and finds no toxic side effect, it was demonstrated that the prescription is safe and reliable.Specifically See following table:
Type Case load It cures Cure rate Effectively It is efficient In vain
Uterine bleeding (dripping amount of bleeding is few not to the utmost, but blood gesture is not as good as metrorrhagia ferociousness) 210 201 96% 208 99% 2
Uterine bleeding(It, cannot be from only under menses are sudden and violent) 160 152 95% 155 97% 5
Uterine bleeding(Under menses are sudden and violent, dripping it is alternately present both not to the utmost) 200 186 93% 190 95% 10
(6)About the reproductive organs organic disease such as fibroid(Exclude cancer)Caused by uterine bleeding, menses it is more than Treatment.
Here combines above-mentioned case diagnosis standard, and according to clinical experience:As above-mentioned symptom and leukorrhea mistake occurs in patient It is more, it smells as of rotten fish plus purple black clot, underbelly drops, whether generally need the inspection of the means such as B ultrasound, CT to make a definite diagnosis is by fibroid, uterus The reproductive organs organic disease such as endometrial hyperplasia(Exclude canceration)Caused by the more than symptom of menses.It is collapsed caused by such illness Leakage, the more than symptom of menses belong to the present invention and cure range.
Selection carrys out the medical patient 19 in here(Because such illness is complex, therefore statistical number of person is less), these patients category In by the reproductive organs organic disease such as fibroid, endometrial hyperplasia(Exclude canceration)Caused by menses it is more than, control Treatment scheme, efficacy assessment standard are same as above, and 19 cases are averagely taken medicine 6 months, are cured 10, effective 13, invalid 6, are cured Rate 53%, effective percentage 70%, achieves good therapeutic effect.
(7)Conclusion:The present invention can be effectively used for treatment disintegration, it is long through it is more than and thus caused by underbelly pain, tired Etc. symptoms, clinical meaning protrude, curative effect highly significant.
The foregoing is merely presently preferred embodiments of the present invention, is not intended to restrict the invention, it is all the present invention spirit and Within principle, any modification, equivalent replacement, improvement and so on should all be included in the protection scope of the present invention.
(8)Short treating period of the present invention.To effectively carrying out course for the treatment of statistics with the patient cured:Dripping urine endlessly, amount of bleeding be less, Blood gesture is to differ for 3-21 days not as good as uterine bleeding patient's healing time of metrorrhagia ferociousness.It, cannot be from uterine bleeding patient only under sudden and violent to menses Most of 3 weeks or so effectively, cures within 8 weeks or so.Under menses are sudden and violent, the dripping uterine bleeding patient 2 weeks or so being alternately present both not to the utmost Effectively, it cures within 6 weeks or so.To the reproductive organs organic disease such as fibroid(Non- canceration)The patient general 5 of caused uterine bleeding Week, left and right was effective, cured within 6 months to 8 months or so, but caused uterine bleeding after the cancerations such as uterine cancer in this way, need to regarding concrete condition and It is fixed.It has absolutely proved short treating period of the present invention, patient suffering, treating both manifestation and root cause of disease can be mitigated as early as possible.
(9)Model case:Illustrate that we's Ji is significant in efficacy below by four model cases, healing time is short, is not easy Recurrence:
Case one:Mrs Yang, Shandong Cao County Lou Zhuancun people native to a places, 40 years old, the time in menstrual period, pain in the back, abdominal pain, body was swollen, and face is yellow, head Bitterly, The blood streamed down, arrives the gynecologial examination of Jinan provincial hospital, and three times, it is invalid to have an injection in the palace of the Qing Dynasty, and rear doctor suggests uterectomy, I It disagrees, goes to here within 2010, it is dialectical using Chinese medicine pulse, it takes decoction of the present invention orally, improves, control through blood after within one month More, it does not recur so far.
Case two:Mrs Hou, Earthquake of Anyang station in Henan city, steel plant worker, 39 years old, disease was being gone to work when sending out, and felt the pain of lower abdomen, eye Evil backstage manipulator fiber crops, go to flow out clot when toilet, invalid through factory's clinic treatment, after remove Anyang hospital diagnosis, B ultrasound, CT examination are found Abdomen hemostasis, cervical hydrocele, the rear palace of the Qing Dynasty, anti-inflammatory have an injection, do not feel any better not only, and abdominal pain aggravates instead, and clot is more than, upon somebody's introduction In going to a doctor to here over 2011, medication takes effect for 3 days, cures within 28 days, does not recur so far.
Case three:Mrs Yang, Henan Province Shangqiu City Liangyuan District, the villages Liu Zhuan, the Hui ethnic group, 48 years old, the unexpected underbelly severe pain in certain day, no Active, malasia is uncomfortable in chest, dizzy, and uterine bleeding sheet clot makes 120 ambulances and is diagnosed as son through X pieces, CT examination to hospital Palace tumor, doctor suggest that operation, household disagree, only expectant treatment, until here, incoordination between the liver and the spleen institute is diagnosed as according to pulse Cause, eat my Chinese medicine, take decoction of the present invention, blood gradually decreases within 1 week, abdominal pain disappearance, terminate substantially in 2 weeks courses for the treatment of, after pass through CT It checks, abdomen clot dissipates, and uterine bleeding is cured.
Case four:Mrs Hao, the villages Wang Tang of Shangqiu Yucheng County people native to a place, 40 years old, because four limbs are felt lazy, menses were more than, without appetite, It is diagnosed to here over 2012, is diagnosed as through pulse drug-induced, through interrogation, be diagnosed as because being beaten in the Xiayi County towns Hui Ting Menses caused by needle are more than, dripping urine endlessly.After taking the present invention, 3 days take effect, and cure within 6 days, after visit 2 years and do not recur.

Claims (3)

1. a kind of Chinese drugs agentia for treating gynaecologic metrorrhagia, it is characterised in that:It is prepared from the following parts by weight of the components:Lotus leaf 10-40 parts, 10-40 parts of lotus, 15-30 parts of the garden burnet of micro- stir-fry, 10-30 parts of CedarLeaves of stir-fry, 10-30 parts of Radix Rhapontici seu Radix Echinopsis, 10-30 parts of Rhizoma Chuanxiong, 10-30 parts of rhizoma zingiberis of bubble, 6-20 parts of cattail pollen, 10-30 parts of Radix Codonopsis, 9-30 parts of osmanthus heart, 10-30 parts of Radix Paeoniae Alba process 20-30 parts of radix rehmanniae preparata, when Return 15-30 parts, 3-8 parts of Radix Glycyrrhizae, 12-30 parts of PORIA ALBA pulverizes 10-40 parts of the deer horn glue of stir-bake to yellowish, 15-40 parts of humus flava usta, rhizoma cyperi 10-30 parts, 10-30 parts of Ramulus Taxilli, 6-20 parts of scouring rush, 10-40 parts of Plant Soot distributes 6-20 parts arbituarily, 9-30 parts of fructus gardeniae, akebi 10-15 parts, 20-30 parts of Chinese cassia tree, 40-60 parts of boys' urine rhizoma cyperi, 20-50 parts of cuttle bone, 15-40 parts of Rhizoma Atractylodis Macrocephalae, 10-30 parts of radix cynanchi atrati, toast 10-30 parts of cat placenta rotates 20-30 parts of prince ' s-feather, and field ends 15-40 parts, 10-30 parts of Chinese yam, 9-20 parts of cimicifugae foetidae, radix scutellariae 10-25 Part, 20-60 parts of dried orange peel, 10-15 parts of radix bupleuri, 20-60 parts of motherwort, 15-20 parts of Radix Astragali, river connects 12-15 parts, 20-60 parts of oyster, 10-20 parts of Cortex Phellodendri, 15-60 parts of hawthorn, 20-60 parts of RADIX POLYGONI MULTIFLORI PREPARATA, 15-20 parts of rhizoma anemarrhenae, 10-20 parts of Divine Comedy, 10-20 parts of radix scrophulariae are red 10-20 parts of ginseng, 12-25 parts of peach kernel, 20-60 parts of cockscomb, 10-15 parts of red raspberry, 10-25 parts of brush-cherry seed, 20-40 parts of oriental wormwood, 10-30 parts of frutus cnidii, 20-60 parts of amethyst, 15-20 parts of angelica tail.
2. a kind of Chinese drugs agentia for treating gynaecologic metrorrhagia according to claim 1, it is characterised in that:By following parts by weight Component is prepared:30 grams of lotus leaf, 30 grams of lotus, 15 grams of the garden burnet of micro- stir-fry, 12 grams of CedarLeaves of stir-fry, 15 grams of Radix Rhapontici seu Radix Echinopsis, 15 grams of Rhizoma Chuanxiong, 12 grams of rhizoma zingiberis of bubble, 10 grams of cattail pollen, 20 grams of Radix Codonopsis, 12 grams of osmanthus heart, 15 grams of Radix Paeoniae Alba, 20 grams of radix rehmanniae preparata of toast, 20 grams of Radix Angelicae Sinensis, 8 grams of Radix Glycyrrhizae, 15 grams of PORIA ALBA pulverizes 15 grams of the deer horn glue of stir-bake to yellowish, 30 grams of humus flava usta, 20 grams of rhizoma cyperi, 15 grams of Ramulus Taxilli, 15 grams of scouring rush, hundred grass 15 grams of frost, distributes 9 grams arbituarily, 12 grams of fructus gardeniae, 12 grams of akebi, 20 grams of Chinese cassia tree, 40 grams of boys' urine rhizoma cyperi, 20 grams of cuttle bone, 15 grams of Rhizoma Atractylodis Macrocephalae, 12 grams of radix cynanchi atrati, 15 grams of toast cat placenta rotate 20 grams of prince ' s-feather, and field ends 30 grams, 20 grams of Chinese yam, 15 grams of cimicifugae foetidae, and 12 grams of radix scutellariae is old 20 grams of skin, 15 grams of radix bupleuri, 30 grams of motherwort, 15 grams of Radix Astragali, river connect 15 grams, 30 grams of oyster, 15 grams of Cortex Phellodendri, 20 grams of hawthorn, and system is first 30 grams of crow, 20 grams of rhizoma anemarrhenae, 20 grams of Divine Comedy, 20 grams of radix scrophulariae, 15 grams of red ginseng, 12 grams of peach kernel, 30 grams of cockscomb, 12 grams of red raspberry are strongly fragrant 12 grams of Li Ren, 30 grams of oriental wormwood, 12 grams of frutus cnidii, 30 grams of amethyst, 15 grams of angelica tail.
3. a kind of Chinese drugs agentia for treating gynaecologic metrorrhagia according to claim 1 or 2, it is characterised in that:The Chinese medicine medicine The dosage form of agent is decoction or pill.
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