CN113164526A - 用于微生物植入的方法和组合物 - Google Patents

用于微生物植入的方法和组合物 Download PDF

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Publication number
CN113164526A
CN113164526A CN201980061790.5A CN201980061790A CN113164526A CN 113164526 A CN113164526 A CN 113164526A CN 201980061790 A CN201980061790 A CN 201980061790A CN 113164526 A CN113164526 A CN 113164526A
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Prior art keywords
composition
microorganism
rrna
sequence
subject
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Pending
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CN201980061790.5A
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English (en)
Chinese (zh)
Inventor
约翰·S·艾德
科琳·卡特克利菲
詹姆斯·H·布拉德
尼古拉斯·贾斯蒂斯
杰西卡·希内斯
苏拉比·泰尔吉
马库斯·F·施克尔伯格
安德鲁·T·程
保罗·麦克莫迪
克里斯蒂安·西贝尔
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Pendulum Therapeutics Inc
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Whole Biome Inc
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Publication of CN113164526A publication Critical patent/CN113164526A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/742—Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/745—Bifidobacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Transplantation (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201980061790.5A 2018-07-19 2019-07-19 用于微生物植入的方法和组合物 Pending CN113164526A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862700682P 2018-07-19 2018-07-19
US62/700,682 2018-07-19
PCT/US2019/042670 WO2020018949A2 (en) 2018-07-19 2019-07-19 Methods and compositions for microbial engraftment

Publications (1)

Publication Number Publication Date
CN113164526A true CN113164526A (zh) 2021-07-23

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Country Link
US (1) US12343360B2 (https=)
EP (1) EP3823651A4 (https=)
JP (2) JP7811843B2 (https=)
CN (1) CN113164526A (https=)
AU (1) AU2019306649A1 (https=)
CA (1) CA3106315A1 (https=)
WO (1) WO2020018949A2 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115960999A (zh) * 2022-12-16 2023-04-14 暨南大学 一套用于筛选高抗炎活性β葡聚糖的生物标志物及其应用
CN118955187A (zh) * 2024-08-01 2024-11-15 江西农业大学 一种多糖基肥料在重金属胁迫条件下提高植物根部机械强度及抗倒伏性能上的应用

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3106315A1 (en) * 2018-07-19 2020-01-23 Pendulum Therapeutics, Inc. Methods and compositions for microbial engraftment
JP2023165053A (ja) * 2020-10-07 2023-11-15 国立大学法人東京農工大学 治療用組成物、治療方法、糞便の評価方法、診断方法、及び予後評価方法
KR102880991B1 (ko) * 2021-12-17 2025-11-03 박선민 뮤신 분해능을 갖는 혼합 균주 및 그의 용도

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20160228476A1 (en) * 2014-10-31 2016-08-11 Whole Biome, Inc. Methods and compositions relating to microbial treatment and diagnosis of disorders
AU2017216285A1 (en) * 2016-02-04 2018-07-26 Microbial Resource Management Health Nv Use of microbial communities for human and animal health
CN109069522A (zh) * 2016-03-14 2018-12-21 物产食品科技股份有限公司 肠内丁酸增加剂及丁酸产生菌增殖剂
CN111372596A (zh) * 2017-08-30 2020-07-03 潘德勒姆治疗公司 用于治疗微生物组相关病症的方法和组合物
CN111432826A (zh) * 2017-10-30 2020-07-17 赛里斯治疗公司 用于治疗抗生素耐药性的组合物和方法
US20210205374A1 (en) * 2018-07-19 2021-07-08 Pendulum Therapeutics, Inc. Methods and compositions for microbial engraftment
CN113677355A (zh) * 2018-09-24 2021-11-19 潘德勒姆治疗公司 微生物组合物及使用方法
WO2022271729A1 (en) * 2021-06-21 2022-12-29 Pendulum Therapeutics, Inc. Compositions comprising microbes and methods of use and making thereof

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