PL3292135T3 - Zastosowanie polipeptydu do wpływania na sygnalizację odpornościową i/lub wpływania na funkcję bariery jelitowej i/lub modulowania stanu metabolicznego - Google Patents

Zastosowanie polipeptydu do wpływania na sygnalizację odpornościową i/lub wpływania na funkcję bariery jelitowej i/lub modulowania stanu metabolicznego

Info

Publication number
PL3292135T3
PL3292135T3 PL16724321.1T PL16724321T PL3292135T3 PL 3292135 T3 PL3292135 T3 PL 3292135T3 PL 16724321 T PL16724321 T PL 16724321T PL 3292135 T3 PL3292135 T3 PL 3292135T3
Authority
PL
Poland
Prior art keywords
polypeptide
barrier function
intestinal barrier
metabolic status
immune signalling
Prior art date
Application number
PL16724321.1T
Other languages
English (en)
Inventor
Clara BELZER
Willem Meindert De Vos
Patrice Daniel Cani
Original Assignee
Wageningen Universiteit
Université Catholique de Louvain
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wageningen Universiteit, Université Catholique de Louvain filed Critical Wageningen Universiteit
Publication of PL3292135T3 publication Critical patent/PL3292135T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Diabetes (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
PL16724321.1T 2015-05-06 2016-05-04 Zastosowanie polipeptydu do wpływania na sygnalizację odpornościową i/lub wpływania na funkcję bariery jelitowej i/lub modulowania stanu metabolicznego PL3292135T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15166598 2015-05-06
PCT/EP2016/060033 WO2016177797A1 (en) 2015-05-06 2016-05-04 Use of a polypeptide for effecting immune signalling and/or affecting intestinal barrier function and/or modulating metabolic status

Publications (1)

Publication Number Publication Date
PL3292135T3 true PL3292135T3 (pl) 2023-01-02

Family

ID=74184294

Family Applications (1)

Application Number Title Priority Date Filing Date
PL16724321.1T PL3292135T3 (pl) 2015-05-06 2016-05-04 Zastosowanie polipeptydu do wpływania na sygnalizację odpornościową i/lub wpływania na funkcję bariery jelitowej i/lub modulowania stanu metabolicznego

Country Status (16)

Country Link
US (2) US10738089B2 (pl)
EP (1) EP3292135B1 (pl)
JP (1) JP6894382B2 (pl)
KR (1) KR20180011130A (pl)
CN (1) CN107980043B (pl)
AU (2) AU2016257315A1 (pl)
BR (1) BR112017023751A2 (pl)
CA (1) CA2984985A1 (pl)
DK (1) DK3292135T3 (pl)
EA (1) EA201700507A1 (pl)
ES (1) ES2934138T3 (pl)
HK (1) HK1252412A1 (pl)
IL (1) IL255405B (pl)
MX (1) MX2017014111A (pl)
PL (1) PL3292135T3 (pl)
WO (1) WO2016177797A1 (pl)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2551642B (en) 2014-10-31 2020-09-23 Pendulum Therapeutics Inc Methods and compositions relating to microbial treatment and diagnosis of disorders
EA201700507A1 (ru) 2015-05-06 2018-05-31 Университе Католик Де Лувен Композиция, клетки, способы получения полипептида, применение полипептида и клеток, способ лечения
CN114276960A (zh) * 2015-09-10 2022-04-05 卢万天主教大学 经巴氏灭菌的艾克曼菌用于治疗代谢病症的用途
EP3790889A4 (en) 2017-03-07 2022-06-08 Psomagen, Inc. DIAGNOSTIC AND THERAPEUTIC COMPOSITIONS TARGETING TOLL-LIKE RECEPTORS AND METHODS THEREOF
US20200246488A1 (en) * 2017-07-17 2020-08-06 The Broad Institute, Inc. Compositions and methods for treating inflammatory bowel diseases
JP2020532515A (ja) 2017-08-30 2020-11-12 ペンデュラム セラピューティクス, インコーポレイテッド マイクロバイオーム関連障害の処置のための方法および組成物
KR102340392B1 (ko) * 2018-10-08 2021-12-17 한국생명공학연구원 우울증의 예방 또는 치료 효과를 가지는 장내 미생물 및 이의 용도
KR102197180B1 (ko) * 2018-10-11 2020-12-31 주식회사 고바이오랩 아커만시아 뮤시니필라 균주 및 이를 포함하는 식욕 억제 및 대사성 질환 예방, 개선, 완화 및 치료용 조성물
CN110079474B (zh) * 2019-04-12 2022-11-25 沈阳药科大学 一种高密度培养艾克曼嗜黏蛋白菌的方法
WO2020226438A1 (ko) * 2019-05-07 2020-11-12 한국생명공학연구원 염증성 장질환의 예방 또는 치료용 펩타이드
CN110227085A (zh) * 2019-07-16 2019-09-13 江苏省中医院 Akkermansia Muciniphila在制备抗抑郁药物或者保健品中的应用
KR102397916B1 (ko) * 2019-10-01 2022-05-17 (주)헬스바이옴 건강한 임산부 모유 유래 혐기성 인체 균주 및 이를 이용한 대사성 질환의 예방 또는 치료방법
CN110950937B (zh) * 2019-11-25 2021-05-04 安徽大学 一种改造的艾克曼菌Amuc_1100蛋白及其制备方法和应用
TW202140520A (zh) * 2020-01-10 2021-11-01 國立臺北科技大學 Tlr2交互作用之胜肽以及包括彼之組合物
CN115666627A (zh) * 2020-03-25 2023-01-31 韩国生命工学研究院 源自嗜黏蛋白阿克曼菌的tars或其片段,及其用途
US20210322492A1 (en) * 2020-04-16 2021-10-21 Amucin Oy Ltd Probiotic strains and uses thereof
CN111690044B (zh) * 2020-05-06 2022-03-01 中南大学湘雅二医院 Amuc1100蛋白的用途
CA3184665A1 (en) 2020-07-01 2022-01-06 Wageningen Universiteit Amuc-1100 polypeptide variants for effecting immune signalling and/or affecting intestinal barrier function and/or modulating metabolic status
KR20220061018A (ko) * 2020-11-05 2022-05-12 한국생명공학연구원 항염 및 조직 재생작용을 갖는 신규 펩타이드
CN113413466B (zh) * 2020-12-15 2022-08-19 和度生物医药(上海)有限公司 用于治疗癌症的amuc_1100和免疫检查点调节剂的组合疗法
CN117304264B (zh) * 2023-11-27 2024-02-06 中国科学院烟台海岸带研究所 一种具有肠屏障保护功能的五肽rp5及其应用

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5102872A (en) * 1985-09-20 1992-04-07 Cetus Corporation Controlled-release formulations of interleukin-2
NL1014380C2 (nl) 2000-02-14 2001-08-15 Friesland Brands Bv Darmwandversterkend voedingsmiddel.
EP1374672B8 (en) * 2001-02-28 2009-11-04 National Institute of Advanced Industrial Science and Technology Drosophila strain carrying bradeion gene(s) transferred thereinto
AU2003296330A1 (en) * 2002-12-10 2004-06-30 Epimmune Inc. Hla-a1, a2 -a3,-a24,-b7,and -b44 tumor associated antigen peptides and compositions
US20050180962A1 (en) 2003-01-30 2005-08-18 Eyal Raz Inactivated probiotic bacteria and methods of use thereof
WO2005030133A2 (en) 2003-09-22 2005-04-07 Yale University Treatment with agonists of toll-like receptors
US20060281818A1 (en) * 2005-03-21 2006-12-14 Sucampo Ag, North Carolina State University Method for treating mucosal disorders
EP2076604A4 (en) 2006-08-31 2009-09-02 Centocor Ortho Biotech Inc GLP-2 MIMIC BODIES, POLYPEPTIDES, COMPOSITIONS, PROCESSES AND USES
WO2008076696A2 (en) 2006-12-18 2008-06-26 Washington University In St. Louis The gut microbiome as a biomarker and therapeutic target for treating obesity or an obesity related disorder
EP2030623A1 (en) 2007-08-17 2009-03-04 Nestec S.A. Preventing and/or treating metabolic disorders by modulating the amount of enterobacteria
FR2944524B1 (fr) 2009-04-17 2012-11-30 Ipsen Pharma Sas Derives d'imidazolidine-2,4-dione et leur utilisation comme medicament
EP2429538B1 (en) 2009-05-11 2015-10-21 Nestec S.A. Non-replicating bifidobacterium longum ncc2705 and immune disorders
WO2011137369A1 (en) * 2010-04-29 2011-11-03 The Regents Of The University Of California Production of gamma-aminobutyric acid by recombinant microorganisms
US9104670B2 (en) 2010-07-21 2015-08-11 Apple Inc. Customized search or acquisition of digital media assets
JP5931076B2 (ja) 2010-10-20 2016-06-08 コーニンクレッカ フィリップス エヌ ヴェKoninklijke Philips N.V. 個別識別化装置
EP2449887B1 (en) 2010-11-05 2016-01-06 Nestec S.A. Method for preparing pet food containing probiotic micro-organisms
EP2449891A1 (en) 2010-11-05 2012-05-09 Nestec S.A. Drinking yoghurt preparations containing non-replicating probiotic micro-organisms
BR112014021388A2 (pt) 2012-02-29 2017-07-18 Ethicon Endo Surgery Inc composições de microbiota e métodos rela-cionados às mesmas
WO2014075745A1 (en) * 2012-11-19 2014-05-22 Université Catholique de Louvain Use of akkermansia for treating metabolic disorders
KR101740893B1 (ko) * 2014-05-20 2017-06-13 주식회사 엠디헬스케어 Akkermansia muciniphila 균에서 유래하는 세포밖 소포를 유효성분으로 함유하는 대사질환의 치료 또는 예방용 조성물
EA201700507A1 (ru) 2015-05-06 2018-05-31 Университе Католик Де Лувен Композиция, клетки, способы получения полипептида, применение полипептида и клеток, способ лечения
CN114276960A (zh) 2015-09-10 2022-04-05 卢万天主教大学 经巴氏灭菌的艾克曼菌用于治疗代谢病症的用途
US11071626B2 (en) 2018-03-16 2021-07-27 W. L. Gore & Associates, Inc. Diametric expansion features for prosthetic valves

Also Published As

Publication number Publication date
KR20180011130A (ko) 2018-01-31
HK1252412A1 (zh) 2019-05-24
US20210147489A1 (en) 2021-05-20
DK3292135T3 (da) 2022-10-31
US10738089B2 (en) 2020-08-11
AU2020267210B2 (en) 2023-10-12
WO2016177797A1 (en) 2016-11-10
CN107980043B (zh) 2021-09-24
US11466057B2 (en) 2022-10-11
EP3292135B1 (en) 2022-09-21
US20180265554A1 (en) 2018-09-20
IL255405B (en) 2022-01-01
IL255405A0 (en) 2017-12-31
EA201700507A1 (ru) 2018-05-31
BR112017023751A2 (pt) 2018-07-31
EP3292135A1 (en) 2018-03-14
ES2934138T3 (es) 2023-02-17
MX2017014111A (es) 2018-02-26
AU2020267210A1 (en) 2020-12-17
JP2018515502A (ja) 2018-06-14
CN107980043A (zh) 2018-05-01
AU2016257315A1 (en) 2017-11-23
CA2984985A1 (en) 2016-11-10
JP6894382B2 (ja) 2021-06-30

Similar Documents

Publication Publication Date Title
HK1252412A1 (zh) 多肽用於作用於免疫信號轉導和/或影響腸屏障功能和/或調節代謝狀態的用途
PT3292135T (pt) Uso de um polipéptido para efetuar a sinalização imunitária e/ou afetar a função de barreira intestinal e/ou regular o estado metabólico
IL252812B (en) Pyrin polypeptide and immune modulation
IL250571B (en) coupling and gasket
GB2561542B (en) Ampoule closure
GB2566753B (en) Full face respirator
IL247551A0 (en) A peptide drug in the form of a dry powder
AU363846S (en) Closure
ZA201704991B (en) Container closure systems
SG11202001400YA (en) Closure
ZA201800643B (en) Closure system
PT3225283T (pt) Fecho corta-fogo
ZA201905760B (en) Tamper evident closure
GB201614915D0 (en) Closure
AP00995S1 (en) Security seal
GB201708099D0 (en) Closure
AU201711445S (en) Closure
PL3163132T3 (pl) Urządzenie do uszczelniania oraz system do nakładania zawierający takie urządzenie
GB201522995D0 (en) A closure system
GB2537810B (en) Flexible seal
GB201506785D0 (en) Face mask and face seal component
GB201504273D0 (en) Overhood seal and use thereof
GB201421519D0 (en) A flood barrier system and a barrier thereof
GB201405864D0 (en) Waterproof closure system