CN1127983C - 免疫调节、抗炎症剂 - Google Patents

免疫调节、抗炎症剂 Download PDF

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Publication number
CN1127983C
CN1127983C CN94109522A CN94109522A CN1127983C CN 1127983 C CN1127983 C CN 1127983C CN 94109522 A CN94109522 A CN 94109522A CN 94109522 A CN94109522 A CN 94109522A CN 1127983 C CN1127983 C CN 1127983C
Authority
CN
China
Prior art keywords
globulin
histamine
present
eosinophilia
diseases
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN94109522A
Other languages
English (en)
Chinese (zh)
Other versions
CN1121430A (zh
Inventor
吉井春夫
深田有里子
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Zoki Pharmaceutical Co Ltd
Original Assignee
Nippon Zoki Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Zoki Pharmaceutical Co Ltd filed Critical Nippon Zoki Pharmaceutical Co Ltd
Publication of CN1121430A publication Critical patent/CN1121430A/zh
Application granted granted Critical
Publication of CN1127983C publication Critical patent/CN1127983C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN94109522A 1993-08-09 1994-08-08 免疫调节、抗炎症剂 Expired - Fee Related CN1127983C (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP21804393A JP3193205B2 (ja) 1993-08-09 1993-08-09 好酸球増多抑制剤
JP218043/1993 1993-08-09
JP218043/93 1993-08-09

Related Child Applications (2)

Application Number Title Priority Date Filing Date
CNA011244763A Division CN1471974A (zh) 1993-08-09 2001-08-01 抗炎症剂
CNA011244771A Division CN1471975A (zh) 1993-08-09 2001-08-01 免疫调节剂

Publications (2)

Publication Number Publication Date
CN1121430A CN1121430A (zh) 1996-05-01
CN1127983C true CN1127983C (zh) 2003-11-19

Family

ID=16713756

Family Applications (3)

Application Number Title Priority Date Filing Date
CN94109522A Expired - Fee Related CN1127983C (zh) 1993-08-09 1994-08-08 免疫调节、抗炎症剂
CNA011244771A Pending CN1471975A (zh) 1993-08-09 2001-08-01 免疫调节剂
CNA011244763A Pending CN1471974A (zh) 1993-08-09 2001-08-01 抗炎症剂

Family Applications After (2)

Application Number Title Priority Date Filing Date
CNA011244771A Pending CN1471975A (zh) 1993-08-09 2001-08-01 免疫调节剂
CNA011244763A Pending CN1471974A (zh) 1993-08-09 2001-08-01 抗炎症剂

Country Status (9)

Country Link
US (1) US5780026A (esLanguage)
EP (1) EP0646376B1 (esLanguage)
JP (1) JP3193205B2 (esLanguage)
KR (1) KR100275174B1 (esLanguage)
CN (3) CN1127983C (esLanguage)
AT (1) ATE192655T1 (esLanguage)
DE (1) DE69424362T2 (esLanguage)
ES (1) ES2146240T3 (esLanguage)
TW (1) TW258664B (esLanguage)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6566386B2 (en) 1993-08-09 2003-05-20 Nippon Zoki Pharmaceutical Co., Ltd. Immunomodulating and antiinflammatory agent
JP3193205B2 (ja) * 1993-08-09 2001-07-30 日本臓器製薬株式会社 好酸球増多抑制剤
IT1278052B1 (it) * 1995-03-14 1997-11-17 Mendes Srl Uso delle immunoglobuline della classe g, in particolare delle immunoglobuline per uso endovenoso o per uso intramuscolare, per
US6861053B1 (en) * 1999-08-11 2005-03-01 Cedars-Sinai Medical Center Methods of diagnosing or treating irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth
US6562629B1 (en) 1999-08-11 2003-05-13 Cedars-Sinai Medical Center Method of diagnosing irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth by detecting the presence of anti-saccharomyces cerivisiae antibodies (asca) in human serum
US7048906B2 (en) 1995-05-17 2006-05-23 Cedars-Sinai Medical Center Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions
JPH0959180A (ja) 1995-08-11 1997-03-04 Nippon Zoki Pharmaceut Co Ltd 活性化免疫グロブリン
US5961969A (en) * 1996-05-14 1999-10-05 Maxim Pharmaceuticals, Inc. Stable circulating histamine levels
US6071942A (en) * 1996-05-14 2000-06-06 Maxim Pharmaceuticals, Inc. Elevation of circulating blood histamine levels
JPH10212246A (ja) 1997-01-30 1998-08-11 Nippon Zoki Pharmaceut Co Ltd 経口投与用製剤
US7232830B2 (en) 1998-06-26 2007-06-19 Elaine A Delack Method for treatment of neurodegenerative diseases and effects of aging
JP2000143536A (ja) * 1998-11-13 2000-05-23 Nippon Zoki Pharmaceut Co Ltd 抗浮腫剤
JP2000143537A (ja) * 1998-11-13 2000-05-23 Nippon Zoki Pharmaceut Co Ltd 細胞接着分子発現抑制剤
US6242473B1 (en) * 1999-01-08 2001-06-05 Maxim Pharmaceuticals, Inc. Treatment and prevention of reactive oxygen metabolite-mediated cellular damage
DE19944122A1 (de) * 1999-09-15 2001-03-29 Wolfgang Loh Histamin-Immunglobulin-Komplexe zur Behandlung von entzündlichen Erkrankungen bei Säugetieren
EP1554572B1 (en) 2001-07-25 2009-10-14 Raptor Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
WO2004075845A2 (en) * 2003-02-24 2004-09-10 The Board Of Trustees Of The Leland Stanford Junior University Methods for treating or preventing autoimmune disease using histamine h1 receptor-blocking agents
JP2008539047A (ja) 2005-04-28 2008-11-13 プロテウス バイオメディカル インコーポレイテッド ファーマインフォーマティックスシステム
KR20090071598A (ko) 2006-09-18 2009-07-01 랩터 파마슈티컬 인코포레이티드 수용체 결합 단백질(rap)-접합체 투여에 의한 간 질환의 치료
US8163308B2 (en) 2007-05-10 2012-04-24 Rajesh Shah Homeopathy-based formulation
PT2398500T (pt) 2009-02-20 2019-06-14 2 Bbb Medicines B V Sistema de entrega de medicamentos à base de glutationas
CN102458374A (zh) 2009-05-06 2012-05-16 实验室护肤股份有限公司 包含活性剂-磷酸钙颗粒复合物的皮肤递送组合物及其使用方法
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5585526A (en) * 1978-12-23 1980-06-27 Nippon Zoki Pharmaceut Co Ltd Remedy for allergic disease

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4704273A (en) * 1982-05-17 1987-11-03 Mcmichael John Methods and materials for treatment of rheumatoid arthritis
US4705685A (en) * 1982-05-17 1987-11-10 Mcmichael John Methods and materials for treatment of disease states involving immunological factors
US4705687A (en) * 1985-06-17 1987-11-10 Ortho Pharmaceutical (Canada) Ltd. Treatment of autoimmune diseases such as rheumatoid arthritis with suppressor factor
US5244902A (en) * 1989-08-21 1993-09-14 Beth Israel Hospital Association Topical application of spiperone or derivatives thereof for treatment of pathological conditions associated with immune responses
IT1237475B (it) * 1989-10-06 1993-06-07 Allergeni modificati chimicamente e procedimento per la loro preparazione
US5192773A (en) * 1990-07-02 1993-03-09 Vertex Pharmaceuticals, Inc. Immunosuppressive compounds
JP3193205B2 (ja) * 1993-08-09 2001-07-30 日本臓器製薬株式会社 好酸球増多抑制剤

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5585526A (en) * 1978-12-23 1980-06-27 Nippon Zoki Pharmaceut Co Ltd Remedy for allergic disease

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CHEMICALABSTRACTS,VOL.115NO.3 1991-07-22 VOLOKHOVSKAYA,et,al."histaglobvlin,and,changes,in,comjunctval,structure,in,vernal,conjunctivivies" *
CHEMICALABSTRACTS,VOL.115NO.3 1991-07-22 VOLOKHOVSKAYA,et,al."histaglobvlin,and,changes,in,comjunctval,structure,in,vernal,conjunctivivies";CHEMICALABSTRACTS,VOL.67,NO.5 1967-07-31 A.GETLIK,et,al,"Long-term,sesitivity,threshold,limit,to,acetylcholine,during,the,treatment,of,pneumo *
CHEMICALABSTRACTS,VOL.67,NO.5 1967-07-31 A.GETLIK,et,al,"Long-term,sesitivity,threshold,limit,to,acetylcholine,during,the,treatment,of,pneumo *

Also Published As

Publication number Publication date
JPH0753406A (ja) 1995-02-28
CN1471975A (zh) 2004-02-04
KR100275174B1 (ko) 2000-12-15
CN1121430A (zh) 1996-05-01
KR950005323A (ko) 1995-03-20
ES2146240T3 (es) 2000-08-01
DE69424362D1 (de) 2000-06-15
ATE192655T1 (de) 2000-05-15
EP0646376B1 (en) 2000-05-10
DE69424362T2 (de) 2000-10-19
CN1471974A (zh) 2004-02-04
JP3193205B2 (ja) 2001-07-30
EP0646376A1 (en) 1995-04-05
TW258664B (esLanguage) 1995-10-01
US5780026A (en) 1998-07-14

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PB01 Publication
C14 Grant of patent or utility model
GR01 Patent grant
C19 Lapse of patent right due to non-payment of the annual fee
CF01 Termination of patent right due to non-payment of annual fee