CN112472631A - Multi-effect eye essence and preparation method thereof - Google Patents

Multi-effect eye essence and preparation method thereof Download PDF

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CN112472631A
CN112472631A CN202011595859.3A CN202011595859A CN112472631A CN 112472631 A CN112472631 A CN 112472631A CN 202011595859 A CN202011595859 A CN 202011595859A CN 112472631 A CN112472631 A CN 112472631A
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eye
eye essence
seed oil
sodium hyaluronate
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CN112472631B (en
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邓伟健
刘立侠
史宝彬
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Youyan Dermatology Research Guangzhou Co ltd
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Youyan Dermatology Research Guangzhou Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37Esters of carboxylic acids
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • A61K8/602Glycosides, e.g. rutin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K8/00Cosmetics or similar toiletry preparations
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    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
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    • AHUMAN NECESSITIES
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    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
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    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
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Abstract

The invention discloses a multi-effect eye essence and a preparation method thereof. The multi-effect eye essence is prepared by matching lima bean seed polysaccharide, big fruit cowberry seed oil, small fruit coffee seed oil, acetylated sodium hyaluronate and a black eye removing composition, wherein the black eye removing composition is a compound of water, propyl gallate, epigallocatechin gallate glucoside and diglucosyl gallic acid, and has multiple effects of moisturizing, removing wrinkles, resisting aging and relieving black eyes and bags under the eyes. The main functional components of the composition are all natural sources, such as the sour bean seed polysaccharide, the big fruit cowberry seed oil, the small fruit coffee seed oil, the acetylated sodium hyaluronate, the black eye removing composition and the like, so that the nursing effect is good, and the dependence on human skin cannot be caused. According to the preparation method, the multi-effect eye essence with good stability and uniform dispersed texture can be prepared by strictly controlling the adding steps and compatibility mixing conditions of the components according to the characteristics of the components of the raw materials in the multi-effect eye essence.

Description

Multi-effect eye essence and preparation method thereof
Technical Field
The invention relates to the technical field of eye care cosmetics, and in particular relates to a multi-effect eye essence and a preparation method thereof.
Background
The skin around eyes becomes worse, black eye circles, fish tail lines, eye bags, edema, dry skin and the like appear when people grow old, sleep is insufficient, the external environment is damaged, and the external image is influenced because people look very hagky and cannot pick the eye bags. With the development of society and the improvement of living standard of people, eye nursing is also paid more attention to people, especially many women siblings. Therefore, the eye care product full of the porcelain enamel is also bred. Among them, eye essence is popular among many consumers as an eye care product that is convenient to use.
However, many eye essences on the market still have single efficacy, are mostly water-replenishing and moisturizing with high efficiency, or are water-replenishing and wrinkle-removing with high efficiency, and have the efficacy of relieving dark eye circles and edema very individually.
Moreover, with the promotion of polypeptide skin care effect in recent years, many eye essences on the market currently also take polypeptide as a main compatible component. For example, chinese patent application CN2020100278243 discloses a small molecule polypeptide eye essence, which comprises palmitoyl pentapeptide-4, acetyl tetrapeptide-15, dipeptide-2, acetyl hexapeptide-8, tripeptide-1, nonapeptide-1, palmitoyl tetrapeptide-7, and carnosine. For example, the Chinese patent application CN2019110934335 discloses a full-effect polypeptide eye essence, which comprises various polypeptide components such as acetyl tetrapeptide-5, dipeptide-2, palmitoyl tetrapeptide-7 and the like. The peptide relates to the fields of hormone, nerve, cell growth and reproduction of human bodies, and excessive polypeptide is added into eye essence and absorbed by the skin of the human bodies, so that not only is the dependence easily formed, but also the disorder of the physiological system of the human bodies is easily caused. Meanwhile, the price of the polypeptide is not good, and the cost of the eye essence is higher when the polypeptide is excessively added into the eye essence.
In addition, many eye essences are added with more animal stem cell tissue components in order to pursue simple efficacy. For example, a stem cell mixture added to small molecule polypeptide eye essence disclosed in chinese patent application CN2020100278243, and an umbilical cord tissue extract added to eye essence milk disclosed in chinese patent application CN 2019104631782. Although the stem cell tissue components can bring better eye care effect, the extraction cost not only makes the price of the eye essence more expensive, but also makes the dependence of human skin stronger.
Disclosure of Invention
The invention provides a multi-effect eye essence and a method for preparing the same, aiming at solving the problems that the existing eye essence is single in effect, and most of effective components added in the existing eye essence are non-natural sources, high in price and easy to generate dependence.
The purpose of the invention is realized by the following technical scheme: the multi-effect eye essence comprises the following components in percentage by weight: 0.35-1.28% of thickening agent, 0.2-0.8% of tamarind seed polysaccharide, 0.6-2.0% of emulsifier, 0.4-3.0% of big fruit cowberry seed oil, 0.1-0.5% of small fruit coffee seed oil, 0.03-0.24% of acetylated sodium hyaluronate, 1.0-3.0% of black eye removing composition and the balance of water; the black eye removing composition is a compound of water, propyl gallate, epigallocatechin gallate glucoside and diglucosylgallate.
The tamarind seed polysaccharide (TAMARINDUS INDICA) has instant water replenishing effect, improves skin hydration degree, can provide silky smooth special skin feeling, can effectively improve skin quality, has good moisturizing effect, increases skin elasticity, reduces skin density, reduces skin roughness and resists aging.
The cranberry (Vaccinium MACROCARPON) seed oil (also called cranberry seed oil) is good in stability, is obtained by squeezing cranberry seeds, is free of solvents and artificial chemicals, contains sterols, tocopherols and the like as main components, has excellent oxidation resistance, can improve skin color and luster, smooth textures, improve skin smoothness, enable skin to be smooth and elastic, activate and repair cells, has remarkable instant moisturizing and moisturizing effects, and is lasting in moisturizing effect.
The COFFEA ARABICA (COFFEA ARABICA) seed oil is rich in fatty acids, including saturated fatty acids of palmitic acid and unsaturated fatty acids of linoleic acid, and the two fatty acids are close in content and balanced with each other, so that the COFFEA ARABICA seed oil is beneficial to quickly permeating a skin layer, can help effectively moisturize the skin, enhance the skin guarantee against external damage, and increase the migration of keratinocytes. Meanwhile, the health-care food also contains high-content natural antioxidant tocopherol, and has remarkable antioxidant and anti-activity, so that the health-care food has a good anti-aging effect.
The propyl gallate is extracted from gallnut, has good effects of relieving and resisting allergy and oxidation resistance, can reduce skin sensitivity, delay aging, and effectively relieve and dispel dark eye circles. Epigallocatechin gallate glucoside is derived from the glycosylated form of green tea epigallocatechin gallate, has very strong antioxidant activity, and has UVB absorbing effect, and can protect skin from light injury. The diglucosylgallic acid can effectively inhibit the activity of tyrosinase and prevent the transfer of melanin, thereby obviously reducing color spots, brightening skin color and improving skin whiteness; in addition, diglucosylgallic acid also has excellent anti-free radical effect and anti-aging effect. The black eye removing composition compounded by water, propyl gallate, epigallocatechin gallate glucoside and diglucosylgallate can be effectively absorbed by skin, effectively reduce melanin deposition around eyes, resist external invasion and free radicals, effectively inhibit the activity of inflammatory factors and reduce skin water loss, thereby effectively relieving and removing black eyes, delaying skin aging and improving skin luster.
The acetylated sodium hyaluronate is completely acetylated sodium hyaluronate, so that the permeability of the skin can be increased, the skin can be permeated to deeper skin, the bioavailability is increased, compared with sodium hyaluronate without acetylation, the resistance of the sodium hyaluronate to hyaluronidase is 13 times stronger, deep water replenishing and moisture preserving are effectively performed, wrinkles are smoothed, the metabolism of skin epidermis and dermis is stimulated, the epidermal defense capacity is activated, autophagy is activated, damaged cells are emptied, and the skin has an excellent natural light pollution defense system and self-cleaning capacity. Meanwhile, the collagen hydrolase can be effectively inhibited, the degradation of collagen is reduced, and the synthesis amount of the collagen hydrolase under light pollution is reduced, so that the skin aging is effectively resisted.
Preferably, the multi-effect eye essence comprises the following components in percentage by weight: 0.8-1.0% of thickening agent, 0.5-0.8% of tamarind seed polysaccharide, 1.0-1.5% of emulsifier, 1.0-2.5% of big fruit cowberry seed oil, 0.2-0.3% of small fruit coffee seed oil, 0.15-0.2% of acetylated sodium hyaluronate, 1.5-2.0% of black eye removing composition and the balance of water.
Preferably, the multi-effect eye essence comprises the following components in percentage by weight: 0.8% of thickening agent, 0.5% of acid bean seed polysaccharide, 1.0% of emulsifier, 1.2% of big fruit bilberry seed oil, 0.2% of small fruit coffee seed oil, 0.15% of acetylated sodium hyaluronate, 1.5% of composition for removing dark circles and the balance of water.
Preferably, the black eye removing composition is a compound of water, propyl gallate, epigallocatechin gallate glucoside and diglucosyl gallate, and consists of 0.1-0.99% of propyl gallate, 0.1-0.99% of diglucosyl gallate, 0.02-0.1% of epigallocatechin gallate glucoside and the balance of water according to mass content.
Preferably, the thickener comprises 0.3-1.1% of sodium polyacryl dimethyl taurate and 0.05-0.18% of xanthan gum by weight percentage of the multi-effect eye essence.
Preferably, the emulsifier is tris (laureth-4) phosphate.
Preferably, the multi-effect eye essence further comprises 1.31-5.95 wt% of a humectant, 1.0-4.0 wt% of an emollient, 0.1-0.7 wt% of an antioxidant and 0.3-0.8 wt% of a preservative.
Preferably, the moisturizing agent comprises 0.01-0.15% of sodium hyaluronate, 1.0-5.0% of propylene glycol and 0.3-0.8% of 1, 2-hexanediol by weight percentage of the multi-effect eye essence. The moisturizing agent consisting of the sodium hyaluronate, the propylene glycol and the 1, 2-hexanediol has lasting moisturizing effect, can penetrate deep into the skin, promotes cell metabolism, improves the hydration degree of the skin, keeps the skin tender for a long time, can further enhance the moisturizing effect on the skin, and provides silky skin feeling.
Preferably, the emollient is cyclopentadimethicone; cyclopenta dimethyl silicone is not greasy, has good spreadability, can provide smooth and moist skin feel for skin, and enables the multi-effect eye essence to have good use skin feel. The antioxidant is vitamin E; the vitamin E has excellent oxidation resistance, and can be added into the multi-effect eye essence to further enhance the anti-aging effect of the multi-effect eye essence. The preservative is phenoxyethanol.
The method for preparing the multi-effect eye essence comprises the following steps:
(1) dissolving the acetylated sodium hyaluronate with water of which the mass is 25-30 times that of the acetylated sodium hyaluronate, and uniformly dispersing the acetylated sodium hyaluronate for later use; mixing the black eye removing composition with the antioxidant, and uniformly dispersing for later use;
(2) adding the thickening agent, the tamarind seed polysaccharide and the humectant into the rest water, heating to 80-85 ℃, and uniformly stirring;
(3) mixing the emulsifier and the emollient, heating to 80-85 ℃, adding the cranberry seed oil, and uniformly stirring;
(4) adding the uniformly stirred material in the step (3) into the uniformly stirred material in the step (2), homogenizing and stirring for 5 minutes at 3000-3300 r/min, preserving heat for 5 minutes, and stirring and cooling;
(5) cooling to below 38 ℃, adding the small fruit coffee seed oil, homogenizing and stirring for 5 minutes at 1800-2000 r/min, and continuing stirring and cooling;
(6) sequentially adding the water-soluble substance of the acetylated sodium hyaluronate for standby in the step (1) and the mixture of the black eye removing composition and the antioxidant, and uniformly stirring;
(7) adding the preservative; homogenizing and stirring at the rotating speed of 1800-2000 r/min for 5 minutes until the materials are completely dispersed;
(8) discharging and filtering to obtain the multi-effect eye essence.
Compared with the prior art, the invention has the following advantages and beneficial effects:
the multi-effect eye essence is prepared from tamarind seed polysaccharide, big fruit cowberry seed oil, small fruit coffee seed oil, acetylated sodium hyaluronate and a black eye removing composition in a compatibility manner, wherein the black eye removing composition is a compound of water, propyl gallate, epigallocatechin gallate glucoside and diglucosyl gallate. Therefore, the eye mask has multiple effects of moisturizing, removing wrinkles, resisting aging, and relieving dark eye circles and under-eye puffiness.
In addition, functional components such as polypeptide and the like are not added in the multi-effect eye essence, and main functional components such as the tamarind seed polysaccharide, the big fruit bilberry seed oil, the small fruit coffee seed oil, the sodium hyaluronate for acetylation, the composition for removing dark circles and the like are all natural sources, so that the multi-effect eye essence is good in nursing effect and cannot cause dependence on human skin.
In addition, the multi-effect eye essence disclosed by the invention can be further matched with a humectant, an emollient and an antioxidant, so that the multi-effect eye essence has more excellent effects of moisturizing, resisting aging and endowing silky skin feeling.
According to the preparation method, the multi-effect eye essence with good stability and uniform dispersed texture can be prepared by strictly controlling the adding steps and compatibility mixing conditions of the components according to the characteristics of the components of the raw materials in the multi-effect eye essence.
Detailed Description
To better illustrate the objects, aspects and advantages of the present invention, the present invention will be further described with reference to specific examples.
In the following examples and comparative examples, tamarind seed polysaccharide is available from Indena under the trade name
Figure BDA0002868080160000051
HS 9070130; cranberry seed oil is available from the Kingston (Givaudan) company under the trade name Cranberry oil; the small fruit coffee seed oil is purchased from Qiwanon (Givaudan) company and has the trade name of Koffee Up; the black eye removing composition is purchased from Qihuadun (Givaudan) company and is sold under the name of Unisoth EG-28, and specifically comprises 0.5% of propyl gallate, 0.5% of diglucosylgallate, 0.05% of epigallocatechin gallate glucoside and the balance of water by mass.
Examples 1 to 5
In the embodiment of the multi-effect eye essence, the raw material compositions of the multi-effect eye essence of embodiments 1-5 in percentage by weight are shown in table 1.
Table 1 raw material composition (in weight percentage, total 100%) of the multi-effect eye essence of examples 1 to 5
Figure BDA0002868080160000061
Figure BDA0002868080160000071
The multi-effect eye essence of the embodiments 1 to 5 is prepared according to the following method, and the specific steps are as follows:
(1) dissolving the acetylated sodium hyaluronate with 25 times of water by mass, and uniformly dispersing for later use; mixing the black eye removing composition with the antioxidant, and uniformly dispersing for later use;
(2) adding the thickener, the tamarind seed polysaccharide and the humectant into the rest water, heating to 80 ℃, and uniformly stirring;
(3) mixing the emulsifier and the emollient, heating to 80 ℃, adding the cranberry seed oil, and uniformly stirring;
(4) adding the uniformly stirred material in the step (3) into the uniformly stirred material in the step (2), homogenizing and stirring for 5 minutes at 3000r/min, preserving heat for 5 minutes, and stirring and cooling;
(5) cooling to below 38 ℃, adding the small fruit coffee seed oil, homogenizing and stirring for 5 minutes at 2000r/min, and continuing stirring and cooling;
(6) sequentially adding the water-soluble substance of the acetylated sodium hyaluronate for standby in the step (1) and the mixture of the black eye removing composition and the antioxidant, and uniformly stirring;
(7) adding the preservative; homogenizing and stirring for 5 minutes at 1800r/min until the mixture is completely dispersed;
(8) discharging and filtering to obtain the multi-effect eye essence.
Comparative example 1
Compared with example 1, the multi-effect eye essence of the comparative example does not contain the acid bean seed polysaccharide and the sodium hyaluronate; the weight percentage of the big fruit cowberry seed oil is 1.45 percent, the weight percentage of the small fruit coffee seed oil is 0.25 percent, and the weight percentage of the composition for removing dark circles is 1.85 percent.
Comparative example 2
Compared with example 1, the multi-effect eye essence of the comparative example does not contain big fruit cranberry seed oil and small fruit coffee seed oil; the weight percentage content of the sour bean seed polysaccharide is 0.8 percent; the weight percentage content of the acetylated sodium hyaluronate is 0.25%; the weight percentage of the composition for removing the dark circles is 2.5 percent.
Comparative example 3
Compared with example 1, the multi-effect eye essence of the comparative example does not contain tamarind seed polysaccharide, cranberry seed oil, small fruit coffee seed oil and acetylated sodium hyaluronate; the weight percentage of the composition for removing the dark circles is 3.55 percent.
Comparative example 4
Compared with example 1, in the multi-effect eye essence of the comparative example, the addition amounts of the tamarind seed polysaccharide, the big fruit cowberry seed oil, the small fruit coffee seed oil and the acetylated sodium hyaluronate are 0.1%, 0.2%, 0.05% and 0.01%, respectively.
Comparative example 5
Compared with example 1, the multi-effect eye essence of the comparative example does not contain the composition for removing dark circles.
Comparative example 6
Compared with example 1, the multi-effect eye essence of the comparative example has the addition amount of the black eye removing composition of 0.6%.
The multi-effect eye essence of comparative examples 1 to 6 was prepared according to the preparation method of example 1.
Performance testing
1. Physical and chemical property test
The multi-effect eye essences of examples 1-5 and comparative examples 1-6 are all yellowish semitransparent viscous liquids, and the matrix is transparent and uniform in texture even in visual observation, so that agglomeration and clotting are avoided; and pH measurement (1:10 aqueous diluted solution) was performed, and the pH values of the multi-effect eye essence of examples 1 to 5 and comparative examples 1 to 6 were 5.7, 6.0, 5.9, 6.2, 6.0, 6.4, 5.6, 6.3, 6.6, and 5.2, respectively.
The multi-effect eye essences of examples 1 to 5 and comparative examples 1 to 6 were subjected to physicochemical property tests of heat resistance (48 ± 2 ℃, 3 months, room temperature recovery), cold resistance (-15 ± 2 ℃, 3 months, room temperature recovery) and cold-heat cycle (24 hours, 3 cycles each at 48 ℃, normal temperature and-15 ℃), and no abnormal phenomena such as turbidity and coagulation appear in the results, and the multi-effect eye essences of examples 1 to 5 and comparative examples 1 to 6 had good physicochemical stability and good weather-proof quality guarantee effects.
2. Use test
Test samples: the multi-effect eye essence of the embodiments 1-5 and the multi-effect eye essence of the comparative examples 1-6.
The testing personnel: the 11 workers who worked more frequently over-the-counter, aged 29, 30, 34, 32, 29, 30, 32, 28, 31, 29, had more obvious under-eye bags, edema and dark circles and had obvious fine wrinkles around the eyes.
The test method comprises the following steps: the multi-effect eye essence of the embodiments 1 to 5 and the multi-effect eye essence of the comparative examples 1 to 6 were sampled by 500g, respectively, and distributed to 11 workers. Each worker used the multi-effect eye essence of examples 1-5 and the multi-effect eye essence of comparative examples 1-6 correspondingly, 2 times a day in the morning and evening, and the eye essence was used continuously for two weeks. And before the corresponding multi-effect eye essence is coated each time, the face is washed by clear water.
1) Black eye removing effect
Skin color difference analysis was performed using a VISA facial Image analysis system and Image-Pro Plus Image analysis software, and the ITA ° value (skin color value) was measured. The larger the ITA degree value of the test analysis is, the brighter and whiter the skin color is, and the better the black eye removing effect is, otherwise, the darker and darker the skin is, the worse the black eye removing effect is. The test results for removing dark circles are shown in table 2.
Table 2 black eye removing test results of the multi-effect eye essence of examples 1 to 5 and comparative examples 1 to 6
Figure BDA0002868080160000091
Figure BDA0002868080160000101
2) Wrinkle-removing and anti-aging effects
Before and after the test, weekly follow-up measurements of the Skin fine lines around the eyes of the subjects were performed using a Skin image analysis system (Skin visualizer SV600), and the results are shown in Table 3.
Table 3 wrinkle-removing and anti-aging test results of the multi-effect eye essence of examples 1 to 5 and comparative examples 1 to 6
Test sample 0 week 1 week 2 weeks Variation value
Example 1 37.2 28.6 22.7 -14.5
Example 2 38.5 30.0 25.6 -12.9
Example 3 40.3 32.3 26.9 -13.4
Example 4 36.8 28.1 22.9 -13.9
Example 5 38.7 30.3 24.8 -13.1
Comparative example 1 37.5 32.5 28.3 -9.2
Comparative example 2 39.2 34.8 31.5 -7.7
Comparative example 3 38.4 36.1 35.1 -3.3
Comparative example 4 40.7 34.7 29.9 -10.8
Comparative example 5 38.8 34.1 30.2 -8.6
Comparative example 6 39.4 33.0 28.2 -11.2
3) Moisturizing effect
Before and after the test, the Moisture content of the skin around the eyes of the subject was subjected to tracking Measurement once a week using a skin Moisture meter, and the Measurement results were represented by set Moisture Measurement values (MMV/%), and the results are shown in table 4.
Table 4 moisturizing test results of the multi-effect eye essence of examples 1 to 5 and comparative examples 1 to 6
Test sample 0 week 1 week 2 weeks Increase rate/%)
Example 1 39.6 46.7 53.2 13.6
Example 2 37.2 44.6 49.4 12.2
Example 3 35.7 43.2 48.6 12.9
Example 4 41.2 48.8 54.3 13.1
Example 5 37.6 44.5 49.9 12.3
Comparative example 1 39.7 43.2 45.5 5.8
Comparative example 2 36.2 40.2 43.5 7.3
Comparative example 3 37.5 39.2 40.7 3.2
Comparative example 4 35.4 41.4 45.5 10.1
Comparative example 5 37.8 42.9 46.7 8.9
Comparative example 6 36.5 42.7 47.3 10.8
4) Relieving eye edema and eye pouch
And (3) observing the eye edema and eye pouch conditions of the testee before and after testing, comparing the observation results before and after testing, and then performing effect division according to standard grades to evaluate the relieving effect of each test sample. Wherein, the evaluation criteria are divided into 5 grades: level I, more than 80% of relief and remarkable effect; level II, relieving 60-80%, and having good effect; level III, relieving by 30-60% and having general effect; level IV, relieving by 10-30% and having poor effect; v grade, the remission is less than 10 percent, and the basic effect is achieved. The results are shown in tables 5 and 6.
Table 5 results of the multi-effect eye essence of examples 1 to 5 and comparative examples 1 to 6 for relieving eye edema
Test sample Grade of rating
Example 1
Example 2
Example 3
Example 4
Example 5
Comparative example 1
Comparative example 2
Comparative example 3
Comparative example 4
Comparative example 5
Comparative example 6
Table 6 results of relieving eye puffiness of eyes with the multi-effect eye essences of examples 1 to 5 and comparative examples 1 to 6
Test sample Grade of rating
Example 1
Example 2
Example 3
Example 4
Example 5
Comparative example 1
Comparative example 2
Comparative example 3
Comparative example 4
Comparative example 5
Comparative example 6
As can be seen from the test results in tables 2 to 6, the multi-effect eye essence of examples 1 to 5 has various effects of removing dark circles, removing pouches, removing edema, removing wrinkles, resisting aging, moisturizing and the like, and can realize excellent and significant expression of various effects compared with the multi-effect eye essence of comparative examples 1 to 6. The results show that the multi-effect eye essence provided by the invention is compatible with the sour bean seed polysaccharide, the big fruit cowberry seed oil, the small fruit coffee seed oil, the acetylated sodium hyaluronate and the black eye removing composition formed by compounding water, propyl gallate, epigallocatechin gallate glucoside and diglucosylgallate, and the components effectively perform synergistic interaction while fully exerting respective characteristics, so that various effects are effectively compatible, and the multi-effect eye essence provided by the invention integrates various effects of removing black eye, removing eye bags, removing eye puffiness, removing wrinkles, moisturizing, resisting aging and the like, and each effect is obviously expressed.
5) Using effect scoring
According to the trial condition of each volunteer on the corresponding multi-effect eye, the use experience sense and the irritation use experience are summarized, the use experience sense is graded (10 grades, 10 grades are fully graded, and the grading results of each group are averaged according to the test values in the group), and the summarized use experience effect is shown in table 7.
Table 7 use experience results of the multi-effect eye essence of examples 1 to 5 and comparative examples 1 to 6
Figure BDA0002868080160000131
Figure BDA0002868080160000141
Note: a. in the using process, when the conditions of pruritus, stabbing pain, pore stimulation, red swelling and the like occur, the stimulation is judged to exist; b. and in the using process, judging that the stimulation is not generated when the condition described by the a does not occur. When the irritability condition appears, the stimulation is directly judged, the test of the test sample is immediately stopped, and a large amount of clear water is adopted for washing.
In conclusion, the multi-effect eye essence disclosed by the invention is prepared from the sour bean seed polysaccharide, the big fruit cowberry seed oil, the small fruit coffee seed oil, the acetylated sodium hyaluronate and the black eye removing composition in a compatibility manner, and has multiple effects of moisturizing, removing wrinkles, resisting aging, relieving black eyes and eye bags. In addition, functional components such as polypeptide and the like are not added in the multi-effect eye essence, main functional components such as the acid soybean seed polysaccharide, the big fruit cowberry seed oil, the small fruit coffee seed oil, the sodium hyaluronate for acetylation and the composition for removing dark circles are all natural sources, and the multi-effect eye essence is good in nursing effect, free of irritation, high in use safety and free of dependence on human skin. In addition, the multi-effect eye essence is further matched with a moisturizing agent, an emollient and an antioxidant, so that the multi-effect eye essence has more excellent effects of moisturizing and resisting aging, and is endowed with smooth skin feeling.
Finally, it should be noted that the above embodiments are only used for illustrating the technical solutions of the present invention and not for limiting the protection scope of the present invention, and although the present invention has been described in detail with reference to the preferred embodiments, it should be understood by those skilled in the art that modifications or equivalent substitutions can be made on the technical solutions of the present invention without departing from the spirit and scope of the technical solutions of the present invention.

Claims (10)

1. The multi-effect eye essence is characterized by comprising the following components in percentage by weight: 0.35-1.28% of thickening agent, 0.2-0.8% of tamarind seed polysaccharide, 0.6-2.0% of emulsifier, 0.4-3.0% of big fruit cowberry seed oil, 0.1-0.5% of small fruit coffee seed oil, 0.03-0.24% of acetylated sodium hyaluronate, 1.0-3.0% of black eye removing composition and the balance of water; the black eye removing composition is a compound of water, propyl gallate, epigallocatechin gallate glucoside and diglucosylgallate.
2. The multipurpose eye essence according to claim 1, which comprises the following components in percentage by weight: 0.8-1.0% of thickening agent, 0.5-0.8% of tamarind seed polysaccharide, 1.0-1.5% of emulsifier, 1.0-2.5% of big fruit cowberry seed oil, 0.2-0.3% of small fruit coffee seed oil, 0.15-0.2% of acetylated sodium hyaluronate, 1.5-2.0% of black eye removing composition and the balance of water.
3. The multipurpose eye essence according to claim 1, which comprises the following components in percentage by weight: 0.8% of thickening agent, 0.5% of acid bean seed polysaccharide, 1.0% of emulsifier, 1.2% of big fruit bilberry seed oil, 0.2% of small fruit coffee seed oil, 0.15% of acetylated sodium hyaluronate, 1.5% of composition for removing dark circles and the balance of water.
4. The multi-effect eye essence according to claim 1, wherein the composition for removing dark circles comprises a complex of water, propyl gallate, epigallocatechin gallate glucoside and diglucosylgallate, and comprises 0.1 to 0.99% of propyl gallate, 0.1 to 0.99% of diglucosylgallate, 0.02 to 0.1% of epigallocatechin gallate glucoside and the balance of water.
5. The multi-effect eye essence according to claim 1, wherein the thickener comprises 0.3-1.1% of sodium polyacryl dimethyl taurate and 0.05-0.18% of xanthan gum by weight percentage of the multi-effect eye essence.
6. The multipurpose eye essence according to claim 1, wherein the emulsifier is tris (laureth-4) phosphate.
7. The multi-effect eye essence according to any one of claims 1 to 6, further comprising 1.31 to 5.95 wt% of a humectant, 1.0 to 4.0 wt% of an emollient, 0.1 to 0.7 wt% of an antioxidant, and 0.3 to 0.8 wt% of a preservative, based on the weight of the multi-effect eye essence.
8. The multi-effect eye essence according to claim 7, wherein the humectant comprises 0.01-0.15% of sodium hyaluronate, 1.0-5.0% of propylene glycol and 0.3-0.8% of 1, 2-hexanediol by weight of the multi-effect eye essence.
9. The multipurpose eye essence according to claim 7, wherein the emollient is cyclopentadimethylsiloxane; the antioxidant is vitamin E; the preservative is phenoxyethanol.
10. The method for preparing the multipurpose eye essence of claim 7, comprising the steps of:
(1) dissolving the acetylated sodium hyaluronate with water of which the mass is 25-30 times that of the acetylated sodium hyaluronate, and uniformly dispersing the acetylated sodium hyaluronate for later use; mixing the black eye removing composition with the antioxidant, and uniformly dispersing for later use;
(2) adding the thickening agent, the tamarind seed polysaccharide and the humectant into the rest water, heating to 80-85 ℃, and uniformly stirring;
(3) mixing the emulsifier and the emollient, heating to 80-85 ℃, adding the cranberry seed oil, and uniformly stirring;
(4) adding the uniformly stirred material in the step (3) into the uniformly stirred material in the step (2), homogenizing and stirring for 5 minutes at 3000-3300 r/min, preserving heat for 5 minutes, and stirring and cooling;
(5) cooling to below 38 ℃, adding the small fruit coffee seed oil, homogenizing and stirring for 5 minutes at 1800-2000 r/min, and continuing stirring and cooling;
(6) sequentially adding the water-soluble substance of the acetylated sodium hyaluronate for standby in the step (1) and the mixture of the black eye removing composition and the antioxidant, and uniformly stirring;
(7) adding the preservative; homogenizing and stirring at the rotating speed of 1800-2000 r/min for 5 minutes until the materials are completely dispersed;
(8) discharging and filtering to obtain the multi-effect eye essence.
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113081879A (en) * 2021-04-30 2021-07-09 广州市科能化妆品科研有限公司 Black eye and pouch removing composition as well as preparation method and application thereof
CN113893215A (en) * 2021-10-09 2022-01-07 广州市涵美化妆品有限公司 Eye tightening and repairing composition, application, eye cream and preparation method thereof
CN115844748A (en) * 2022-12-16 2023-03-28 优颜皮肤科学研究(广州)有限公司 Eye composition and preparation method and application thereof

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10076479B1 (en) * 2018-05-08 2018-09-18 Avon Products, Inc. Methods for treating skin
US20200093732A1 (en) * 2018-09-21 2020-03-26 Shanghai Juku Cosmetic CO., LTD Facial mask composition and its preparation method
CN110974729A (en) * 2019-12-20 2020-04-10 广州市玉鑫化妆品有限公司 Eye-bag removing eye cream and preparation method thereof
CN111265460A (en) * 2020-03-13 2020-06-12 佛山市奥姿美生物科技有限公司 Skin barrier repair compositions and uses thereof
CN111603412A (en) * 2020-06-15 2020-09-01 广州花言草语生物科技有限公司 Essential oil for removing striae gravidarum and preparation method thereof

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10076479B1 (en) * 2018-05-08 2018-09-18 Avon Products, Inc. Methods for treating skin
US20200093732A1 (en) * 2018-09-21 2020-03-26 Shanghai Juku Cosmetic CO., LTD Facial mask composition and its preparation method
CN110974729A (en) * 2019-12-20 2020-04-10 广州市玉鑫化妆品有限公司 Eye-bag removing eye cream and preparation method thereof
CN111265460A (en) * 2020-03-13 2020-06-12 佛山市奥姿美生物科技有限公司 Skin barrier repair compositions and uses thereof
CN111603412A (en) * 2020-06-15 2020-09-01 广州花言草语生物科技有限公司 Essential oil for removing striae gravidarum and preparation method thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
国家药品监督管理局: "兰芝致美紧颜眼部修护精华液", 《HTTPS://WWW.NMPA.GOV.CN/DATASEARCH/SEARCH-INFO.HTML?NMPA=AWQ9MJAYODAZJML0ZW1JZD0YYZLIYTM4NDC1OWM5NTC3MDE3NTLJZGM3ZWZJMDQ0MW》 *
电子凭证-国产非特殊用途化妆品备案信息服务平台: "梵婕缇臻萃明眸亮采眼精华", 《HTTP://FTBA.NMPA.GOV.CN:8181/FTBAN/ITOWNET/HZP_BA/FW/PZ.JSP?PROCESSID=20191101172825UE4G7&NID=20191101172825UE4G7》 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113081879A (en) * 2021-04-30 2021-07-09 广州市科能化妆品科研有限公司 Black eye and pouch removing composition as well as preparation method and application thereof
CN113893215A (en) * 2021-10-09 2022-01-07 广州市涵美化妆品有限公司 Eye tightening and repairing composition, application, eye cream and preparation method thereof
CN113893215B (en) * 2021-10-09 2023-08-08 广州市涵美化妆品有限公司 Eye tightening and repairing composition, application and eye cream and preparation method thereof
CN115844748A (en) * 2022-12-16 2023-03-28 优颜皮肤科学研究(广州)有限公司 Eye composition and preparation method and application thereof

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