CN111603412A - Essential oil for removing striae gravidarum and preparation method thereof - Google Patents
Essential oil for removing striae gravidarum and preparation method thereof Download PDFInfo
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/925—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of animal origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Zoology (AREA)
- Medicines Containing Plant Substances (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses an essential oil for removing striae gravidarum and a preparation method thereof, wherein the essential oil comprises the following components in parts by mass: 40-60 parts of quinoa seed oil, 20-30 parts of moringa seed oil, 5-15 parts of small-fruit coffee seed oil and 1-5 parts of horse oil. The preparation method comprises the following steps: at normal temperature, weighing the components according to the prescription amount, putting the components into a vessel, stirring the components in the same direction for 3 to 10 minutes to fully mix and fuse the components, and then packaging and sealing the mixture to obtain the finished product. The product has good effect of removing striae gravidarum, is nontoxic and environment-friendly, and has high use safety.
Description
Technical Field
The invention relates to the field of skin care and beauty products, in particular to essential oil for removing striae gravidarum and a preparation method thereof.
Background
Striae gravidarum is a linear skin lesion of the abdomen-based dermis generated after pregnancy of women, is one of the most common connective tissue changes during pregnancy, and about 55-90% of pregnant and lying-in women suffer from striae gravidarum. Early stretch marks often appear as flat, pink or red stripes that gradually stand out on the skin surface, turning into longer, wider purplish-red stripes. In the period of several months to several years, the skin lesion gradually shrinks and is accompanied with hypopigmentation and loss to form scar-like atrophy lines parallel to the skin tension line. The skin damage is caused to breasts, abdomens, buttocks and thighs, and sometimes has subjective symptoms such as pruritus, burning pain and the like. Some postpartum women often feel self-inferior due to the fact that the postpartum women suffer from the failure of treating the stretch marks, swim with swimsuits or bubble hot springs which are afraid of wearing sexuality in summer, dare not to wear ultra-short skirts and shorts, and worry about that the spouse is suspect and loses confidence; some women lack correct understanding of treatment of striae gravidarum, and some women are treated by a bias or irregular beauty institution, some women are worried and scratched due to intolerance of severe pruritus and burning sensation, and then local infection occurs, and then the skin ointment containing hormone components is used for treatment, so that the effect is not ideal, the women feel unfair in terms of restraint and are exuberant, some postpartum women have severe depression, and the quality of life is greatly reduced.
Although the stretch marks do not threaten the physical health of patients, the stretch marks can cause psychological diseases because the stretch marks affect the beautiful appearance of the skin. Until now, the pathogenesis, high-risk factors and exact treatment means of the disease are still in the exploration stage and gradually receive wide attention of students in the fields of dermatology, plastic department and the like. The research shows that: the significant reduction in type I and type III procollagen expression by fibroblasts in striae of pregnancy compared to normal fibroblasts suggests that the disease may present an abnormal condition of fibroblast metabolism. Stretch marks are an atrophic linear scar, a type of striae distensae, which is named because it occurs during pregnancy. The pathogenesis and high risk factors of striae gravidarum are not clear, and the clinical prevention and treatment effects are not good enough. The current commonly used methods for relieving stretch marks comprise weight-losing exercise methods, external medicines, external stretch mark skin care products, medical means such as various laser treatment methods, radio frequency treatment methods, microcrystalline ablation, and the like. The effect of weight-reducing exercise on stretch marks is not clear, and the postpartum mother is in lactation, which has certain limitations; although the medical methods such as laser, radio frequency and the like have certain curative effect, the cost is high, the support of corresponding equipment is needed, and the feasibility for common women is low; compared with external medicines and skin care products, the skin care product has high acceptance, and can be used for preventing and relieving prenatal striae gravidarum. At this stage, the use of skin care products for external application is still the most common and most accepted method for stretch marks. However, the striae gravidarum removing external skin care product in the prior art has a poor striae gravidarum removing effect, so that the pregnant woman can recover the aesthetic feeling of the abdominal skin before pregnancy, the life quality of the postpartum woman is improved, and the striae gravidarum removing external skin care product is a search target of scientific researchers.
Disclosure of Invention
Aiming at the defects of the prior art, the invention solves the technical problem of how to improve the striae gravidarum removing effect of the striae gravidarum removing product.
In order to solve the technical problems, the technical scheme adopted by the invention is that the essential oil for removing striae gravidarum comprises the following components in parts by mass: 40-60 parts of quinoa seed oil, 20-30 parts of moringa seed oil, 5-15 parts of small-fruit coffee seed oil and 1-5 parts of horse oil.
Preferably, the feed additive is prepared from the following components in parts by mass: 45-52 parts of quinoa seed oil, 23-28 parts of moringa seed oil, 7-10 parts of small-fruit coffee seed oil and 2-3 parts of horse oil.
The small-fruit coffee seed oil is whole oil extracted from small-fruit coffee raw coffee seeds by a cold pressing method.
The quinoa seed oil and moringa seed oil are prepared by a cold pressing method.
The invention also aims to solve the technical problem of providing a preparation method of the essential oil for removing the striae gravidarum.
Therefore, the technical scheme provided by the invention is that the preparation method of the essential oil for removing the striae gravidarum comprises the following steps: at normal temperature, weighing the components according to the prescription amount, putting the components into a vessel, stirring the components in the same direction for 3 to 10 minutes to fully mix and fuse the components, and then packaging and sealing the mixture to obtain the finished product.
Compared with the prior art, the product has better effect of removing striae gravidarum, is nontoxic and environment-friendly, and has high use safety.
Detailed Description
The following examples are given to further illustrate the embodiments of the present invention, but are not intended to limit the invention.
Example 1:
essential oil for removing striae gravidarum comprises the following components in parts by mass: 40 parts of quinoa seed oil, 30 parts of moringa seed oil, 5 parts of small-fruit coffee seed oil and 5 parts of horse oil.
Example 2:
essential oil for removing striae gravidarum comprises the following components in parts by mass: 45 parts of quinoa seed oil, 28 parts of moringa seed oil, 7 parts of small-fruit coffee seed oil and 3 parts of horse oil.
Example 3:
essential oil for removing striae gravidarum comprises the following components in parts by mass: 48 parts of quinoa seed oil, 25 parts of moringa seed oil, 8 parts of small-fruit coffee seed oil and 3 parts of horse oil.
Example 4:
essential oil for removing striae gravidarum comprises the following components in parts by mass: 52 parts of quinoa seed oil, 23 parts of moringa seed oil, 10 parts of small-fruit coffee seed oil and 2 parts of horse oil.
Example 5:
essential oil for removing striae gravidarum comprises the following components in parts by mass: 60 parts of quinoa seed oil, 20 parts of moringa seed oil, 15 parts of small-fruit coffee seed oil and 1 part of horse oil.
The preparation method of the above examples 1 to 5: at normal temperature, weighing the components according to the prescription amount, putting the components into a vessel, stirring the components in the same direction for 3 to 10 minutes to fully mix and fuse the components, and then packaging and sealing the mixture to obtain the finished product.
The invention is formed by mixing three vegetable oils of quinoa seed oil, moringa seed oil and small fruit coffee seed oil and animal oil horse oil, is non-toxic, environment-friendly and safe to use, and has the following theoretical basis for effectively removing striae gravidarum:
quinoa seed oil is rich in important fatty acids (linoleic acid and alpha-linolenic acid) and its comparison with the main fatty acid content of common grains is as follows:
from table 1, it can be seen that quinoa seed oil fatty acid has a composition closest to that of corn oil, except that quinoa seed oil has particularly good skin penetration and good oil appearance clarity, and is a natural emollient oil well suited for use in cosmetics.
The moringa seed oil contains abundant fatty acids (linoleic acid and alpha-linolenic acid), wherein the content of unsaturated fatty acids is 81.24%, and the content of oleic acid is 72.19%. The unsaturated fatty acid can reduce fat and total cholesterol content in blood, prevent thrombosis, and discharge toxin, and is beneficial to human health.
Researches show that quinoa seed oil and moringa seed oil contain abundant essential fatty acids required by human skin, and the essential fatty acids have multiple protective functions on the skin and can maintain the integrity of cell membranes. Essential fatty acids are present in phospholipids, which are the major components of cell membranes, and atopic dermatitis is liable to occur in the absence of essential fatty acids because the absence of essential fatty acids easily causes epithelial and fibroblast maturation disorders, fatty acid structure of cell membrane lipids of skin tissues is changed, permeability is increased, and antigens and microorganisms are easily penetrated. Essential fatty acids thus play an important role in maintaining skin structure and skin physiology. The most intuitive manifestation of the lack of essential fatty acids is a defect in the barrier function of the skin, and thus essential fatty acids play an important role in maintaining the barrier function of the skin.
The quinoa seed oil and the moringa seed oil are both derived from natural plants, are prepared by adopting a green and environment-friendly cold pressing method so as to better protect the inherent oil and fat nutrient components and preserve the bioactive functional components thereof, have high safety, good skin affinity and good permeability, and can be used in skin care products to improve the symptoms of skin elasticity, desquamation, pruritus and the like; has effects of repairing skin barrier function, keeping moisture, and reducing percutaneous water loss;
therefore, the quinoa seed oil and the moringa seed oil both contain rich fatty acid (linoleic acid and alpha-linolenic acid), so that the quinoa seed oil and the moringa seed oil have strong antioxidant activity, the effects of resisting free radicals and discharging toxins, and the striae gravidarum can be effectively removed.
The cafestia pipiens oil (green coffee oil) is a whole oil extracted from the raw coffee seeds of cafestia pipiens by the cold pressing method, and contains abundant cafestol and kahweol components, with high concentrations of unsaponifiable and palmitic and oleic acids, especially up to 10% in cafestol and kahweol, whereas the palmitate esters of cafestol and kahweol can increase the activity of the multifunctional groups of certain enzymes, which can act when the cells are facing xenobiotics, against oxidative stress. The cucurbitacin in coffee plays an important role in cellular energy metabolism and DNA repair. In addition, the small fruit coffee seed oil has antioxidant and anti-inflammatory effects, can promote the replacement of the natural water-fat membrane of the skin, thereby preventing dehydration, is suitable for treating dry and reactive skin, and can provide high-efficiency tissue regeneration capability.
The three vegetable oils have natural sources, high safety, good skin affinity and good permeability, and effectively help striae gravidarum patients to improve skin elasticity, desquamation, pruritus and other symptoms. In addition, the three kinds of oil contain rich unsaturated fatty acid, have strong inoxidizability, effectively resist free radicals, supplement essential fatty acid of the skin, reconstruct the fatty acid structure of cell membrane lipid of skin tissues and well play important roles in maintaining the skin structure and the physiological functions of the skin.
Horse oil has been recorded in the compendium of materia Medica: horse fat is sweet, mild and grows hair; can be used for treating facial blackening (whitening) and rhagadia manus et pedis; it can be used for relieving muscle spasm and facial paralysis. Horse oil is commonly used in traditional Chinese medicine for treating chilblain and scald. Horse oil has strong affinity and permeability to skin mucosa, is easy to be absorbed by skin, and has effects of accelerating skin metabolism, enhancing cell activity, and resisting skin aging. The horse oil has fatty acid similar to human skin, and can be used as natural moisture keeping component. Horse oil is suitable for sensitive skin, and has better effect than vegetable oil. The horse oil has excellent anti-wrinkle function, contains more than 60% of unsaturated fatty acid, contains abundant VE and a certain amount of VA, and contains natural antioxidant active components.
To further illustrate the beneficial results of the present invention, the following comparative experiments were conducted on the products of the present invention and similar products on the market:
(1) comparing incidence of the pregnancies;
a comparison experiment is carried out by taking the product of the invention and similar products sold in the market from the 19 th week of pregnancy, 150 pregnant women are divided into three groups, 50 cases of the product of the invention and the massage group are applied, 50 cases of the product of the invention are singly applied, and 50 cases of the similar products sold in the market are used as a control group. The results show that the incidence rate of striae gravidarum is 5% when only the product of the invention and the massage group are used, the incidence rate of striae gravidarum is 30% when the product of the invention is used alone, and the incidence rate of striae gravidarum is 60% when the product of the invention is used alone.
(2) Striae gravidarum color uniformity, striae gravidarum looseness and striae gravidarum severity contrast;
the subjects were divided into two groups with the midline of the abdomen as the boundary, the abdomen was divided into 2 regions, one side of the group was selected as test group 1 and test group 2 using the product of the present invention and the commercially available similar products according to the random principle, and the other side was used as a blank control group. The product is used in the morning and evening for 2 times every day, the application amount is not less than 10mg/cm < 2 >, the massage is not less than 15min each time, and the palm is slightly looped when the product is applied until all the products or similar products sold in the market are absorbed. Subjects were assessed at week 0 (baseline), week 2, week 4, week 8, week 12.
Clinical evaluation:
striae gravidarum color uniformity, striae gravidarum looseness and striae gravidarum severity were assessed visually by a professional physician. The scoring criteria was 5 points, with 0 points representing the best condition and 5 points representing the most severe condition. Wherein the striae gravidarum color uniformity reflects the difference in striae gravidarum color from the surrounding skin color, the higher the score, the greater the difference from the surrounding skin color. Striae gravidarum laxity reflects striae gravidarum elasticity, with higher scores being less elastic. Striae gravidarum severity reflects the degree of striae gravidarum as a whole, with higher scores being more severe.
Evaluation equipment: using a skin scanner (
VC98, CK company, germany) were photographed by an electronic digital camera system, skin parameters were analyzed, and the condition of the skin was reflected. Wherein the SEW value reflects the skin texture by the ratio of the width and the number of the skin texture, the higher the value, the coarser the skin texture. The C-R5 value is the degree of skin roughness, reflecting the skin wrinkle depth, the higher the value, the deeper the skin wrinkles, the rougher the skin.
The following table of the striae gravidarum color and texture parameter variations was evaluated:
the data in the table show that the product and the like products sold in the market have good effect on removing striae gravidarum, but all indexes of the removing effect of the product are greatly superior to those of the like products sold in the market, and the product has remarkable progress.
In conclusion, compared with the prior art, the product has better effect of removing striae gravidarum, is prepared by mixing pure natural vegetable oil and animal oil, and is non-toxic, environment-friendly, safe and reliable to use.
The embodiments of the present invention have been described in detail with reference to the examples, but the present invention is not limited to the described embodiments. It will be appreciated by those skilled in the art that various changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the appended claims.
Claims (5)
1. The essential oil for removing striae gravidarum is characterized by comprising the following components in parts by mass: 40-60 parts of quinoa seed oil, 20-30 parts of moringa seed oil, 5-15 parts of small-fruit coffee seed oil and 1-5 parts of horse oil.
2. The essential oil for removing striae gravidarum according to claim 1, which comprises the following components in parts by mass: 45-52 parts of quinoa seed oil, 23-28 parts of moringa seed oil, 7-10 parts of small-fruit coffee seed oil and 2-3 parts of horse oil.
3. The striae gravidarum removing essential oil of claim 1 or 2, wherein the cappuccino seed oil is whole oil extracted from cappuccino seeds by a cold pressing method.
4. The essential oil for removing the striae gravidarum of claim 1 or 2, wherein the quinoa oil and the moringa seed oil are prepared by a cold pressing method.
5. The preparation method of the essential oil for removing the striae gravidarum according to claim 1 or 2, characterized in that the components are respectively weighed according to the prescription amount and put into a vessel at normal temperature, and stirred for 3 to 10 minutes in the same direction, so that the components are fully mixed, uniformly fused, packaged and sealed to obtain the finished product.
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