CN105078823A - Weight-reducing composition and preparation method thereof - Google Patents
Weight-reducing composition and preparation method thereof Download PDFInfo
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- CN105078823A CN105078823A CN201510500858.9A CN201510500858A CN105078823A CN 105078823 A CN105078823 A CN 105078823A CN 201510500858 A CN201510500858 A CN 201510500858A CN 105078823 A CN105078823 A CN 105078823A
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Abstract
The invention discloses a weight-reducing composition. The weight-reducing composition comprises base oil and weight-reducing factors dispersed in the base oil, and the weight-reducing factors are a mixture of Arabian coffee seed oil, oilseed rape sterols substance and tocopherol. The weight-reducing composition has the advantages that by the aid of the Arabian coffee seed oil, the oilseed rape sterols substance and the tocopherol contained in the weight-reducing composition, content of SREBP-1 (sterol-regulatory element-binding protein-1) is decreased by means of improving adiposine level to reduce adipogenesis and inhibit adipocyte differentiation, and adipose tissue decomposition is accelerated by means of activating lipolytic enzyme, so that the purpose of weight reduction is achieved; meanwhile, skin sagging is improved by means of stimulating collagen synthesis so as to firm the skin, and the skin surface is kept smooth by an estrogen regulating function of the tocopherol; the weight-reducing composition combining the Arabian coffee seed oil, the oilseed rape sterols substance and the tocopherol can promote weight reduction, skin firming and skin smoothing synergistically.
Description
Technical field
The present invention relates to cosmetic technical field, be specifically related to a kind of Weight reducing compound and preparation method thereof.
Background technology
Along with growth in the living standard, living-pattern preservation, the sickness rate of obesity is in increasing trend year by year, and the trend that becomes younger is obvious.According to the authoritative investigation report display of portion, current Chinese overweight person reaches 22.4%, and extremely overweight people is 3.01%.It is attractive in appearance that obesity not only affects stature, also can people be made to a certain extent to produce inferiority complex, but also can with some other Chronic Non-Communicable Diseasess relevant to obesity, the prevalence as diabetes, metabolism syndrome, hypertension, cardiovascular and cerebrovascular disease etc. is also the trend obviously risen.
The method of current treatment of obesity is a lot, and mostly Western medicine be amphetamine based on appetite-suppressing, to improve the thyroid hormones of metabolism, or other purgatives medicine things, and comparatively greatly, life-time service damages human body these poisonous side effect of medicine; And Chinese medicine for oral administration, take effect comparatively slow, taste is difficult to accept and make patient be difficult to persevere; Keeping fit through sport is a kind of fat-reducing mode of health, but needs to adhere to for a long time, also need to keep on a diet, otherwise body weight easily rebounds; Usually containing cathartic in commercially available various diet teas, its anti-obesity mechanism is also that to let out be main, and inadvisable; The fat-reducing instant effect although go on a diet, rebound rate is high, and has a strong impact on healthy.
All there is certain defect in above-mentioned method of weight-reducing.Therefore, be necessary to study a kind of healthy, effective diet products, to meet the different demands of various overweight people.
Summary of the invention
One object of the present invention is to provide a kind of Weight reducing compound, and this Weight reducing compound effectively, is healthily lost weight by regulating the decomposition of the differentiation of adipose cell and acceleration fatty tissue to reach simultaneously.
Another object of the present invention is the preparation method providing a kind of above-mentioned Weight reducing compound, can obtain the Weight reducing compound that fat-reducing effect is excellent.
For reaching this object, the present invention by the following technical solutions:
There is provided a kind of Weight reducing compound, comprise base oil and be scattered in the fat-reducing factor in described base oil, the described fat-reducing factor is the mixture of Coffea arabica seed oil, campesterol class material and tocopherol.
The generation of fat comprises the synthesis of fatty acid and the synthesis of triglyceride, and both all can carry out in liver and fatty tissue.Lipogenesis gene expression is subject to nutrient and hormone affected, and their effect can regulate and control by SREBP-1 (Sterol regulatory element binding protein-1), in fatty tissue regulate and control by PPAR.Lipogenesis involves a series of different step, comprising a lot of regulative mode, also comprises allostery, covalent modification and change gene expression.Increasing people recognize that adiposine can suppress athero, and it both can reduce the absorption of food, can affect again specific metabolic pathway in fat and its hetero-organization.Adiposine can excite adipose cell to decompose and generate glycerol, and this effect is mainly by accelerating fatty acid oxidation and suppressing lipogenesis two kinds of approach jointly to reach.
As preferred version of the present invention, the above-mentioned fat-reducing factor is preferably the mixture of Coffea arabica seed oil and campesterol.Coffea arabica (COFFEAARABICA) seed oil has excellent emulsifying, dispersion and lubricating ability, can be used as conditioner, emollient is applied to personal-care supplies field; Campesterol stems from Brassica campestris L extract, campesterol of the present invention refers to campesterol and/or brassicasterol, belong to the one in campesterol class material, refer to that molecular structure is similar to natural product and the synthetic material of campesterol, effectively can reduce cholesterol.Campesterol class material belongs to plant sterol, plant sterol is divided into 4-demethlyate sterol, 4-methylsterol and 4,4'-dimethylsterols three class, demethlyate sterol mainly contains Β-sitosterol, stigmasterol, campesterol and brassicasterol etc., mainly be present in the structure of plant sterol in the seed of plant and the structure basic simlarity of animality sterol, unique difference be c-4 position connect the difference of number of methyl groups and c-11 position side chain, the small difference just on these side chains causes and makes it have various physiological functions.In the fat-reducing factor that Coffea arabica seed oil and campesterol class material form, containing multiple different active component, be rich in diterpene product especially, mainly comprise cafestrol cetylate and special campesterol class material, show the multiple different mechanism of action.The fat-reducing factor of the present invention reaches the object of fat-reducing by following approach: (1) improves adiposine level, reduces the content of SREBP-1 (Sterol regulatory element binding protein-1), thus reduces lipogenesis; (2) be rich in how far unsaturated fatty acid, can lipogenesis be reduced; (3) can the synthesis of stimulation collagen, for regional adipose tissue and cutis laxa, there is remarkable and potent effect, there is the synergism that induced lipolysis simultaneously decomposes, fibrous tissue and the skin corium cell of skin can be rebuild; (4) can Stearoyl Coenzyme A be suppressed, activate lipolytic enzyme (as HSL hormone-sensitive lipase) simultaneously; Regional adipose tissue is had to the effect of accelerated decomposition, also can regulate and control suppression lipogenesis simultaneously, improve the area distribution of fatty tissue at human body, build again by corium and subcutaneous reticular tissue fiber are carried out recombinating, make skin consolidation more; Vitamin E (VitaminE) is a kind of fatsoluble vitamin, its hydrolyzate is tocopherol, it is one of topmost antioxidant, be dissolved in the organic solvents such as fat and ethanol more, water insoluble, stablize heat, acid, tocopherol can promote sex hormones secretion, the estrogen concentration of women is increased, there is the function improving blood circulation, adjustment hormone, activation hypophysis.The Coffea arabica seed oil contained in Weight reducing compound of the present invention, campesterol class material and tocopherol, the content reducing SREBP-1 by improving adiposine level reduces lipogenesis and suppresses Adipocyte Differentiation, the decomposition of fatty tissue is accelerated by activating lipolytic enzyme, thus reach the object of fat-reducing, improved the slackness of skin by the synthesis of stimulation collagen simultaneously, to reach the object of Rosemary Extract, skin surface is made to keep smooth by the estrogen regulating function of tocopherol, the present invention is by Coffea arabica seed oil, campesterol class material and tocopherol Combination application, can work in coordination with and accelerate loss of weight, Firm, glabrous skin.
Particularly, described base oil is Oleum Vitis viniferae, Prunus dulcis oil and the mixture of Semen Tritici aestivi germ oil; Semen Vitis viniferae contains multiple nutritional components, wherein has the Oleum Vitis viniferae of 14 ~ 17%, and the rich in nutrition content of Oleum Vitis viniferae has approved biological safety, has very highly nourishing health care effect.Mineral element potassium containing needed by human in Oleum Vitis viniferae, sodium, calcium and ferrum and vitamin A, vitamin D, vitamin E, particularly high-load vitamin E has stronger non-oxidizability, becomes sour, extends its shelf shelf-life and have certain effect inhibited oxidation.Oleum Vitis viniferae can defying age, health invigorating, can diseases prevention, enhancing development and improve health conditions, content is higher, can defying age, health invigorating, can diseases prevention, enhancing development and improve health conditions.In beauty industry, Oleum Vitis viniferae absorbs because oil is oiliness, skin-friendly strong, be easy to skin, is suitable for any skin quality, therefore uses as adjuvant in a lot of superior cosmetics, can skin nutrition cell, prevent pachylosis and keratinization, and non-stimulated, be a kind of good natural skin care agent.Prunus dulcis (PRUNUSAMYGDALUSDULCIS) oil refers to Prunus dulcis seed extract, be Semen pruni armeniacae extract again, as having Shu Min effect during massage oil, when it dilutes above-mentioned Coffea arabica seed oil with campesterol class material as base oil, can well alleviate, even avoid skin to produce allergic phenomena; Essential fatty acid in Semen Tritici aestivi germ oil is up to more than 80%, and linoleic acid accounts for 55%.Unsaturated fatty acid can keep the mobility of cell membrane, makes cell keep physiological function.Contribute to making cholesterol esterification, reduce cholesterolemia and triglyceride levels, blood viscosity is declined, improves microcirculation.The present invention is by being scattered in above-mentioned Oleum Vitis viniferae, Prunus dulcis oil and the base oil that forms of Semen Tritici aestivi germ oil by Coffea arabica seed oil and campesterol class material, the user of allergic constitution is avoided to produce anaphylaxis in this Weight reducing compound process of use, use a small amount of Coffea arabica seed oil just can reach good fat-reducing effect with campesterol class material simultaneously in Weight reducing compound of the present invention, and then reduce the production cost of Weight reducing compound.
As preferred version of the present invention, by weight, described base oil comprises 20 ~ 50 parts of Oleum Vitis viniferaes, 5 ~ 20 parts of Prunus dulcis seed oil and 0 ~ 3 part of Semen Tritici aestivi germ oil, the content of described Oleum Vitis viniferae is 20 ~ 50 parts, such as 21 parts, 22 parts, 23 parts, 25 parts, 30 parts, 32 parts, 35 parts, 38 parts, 40 parts, 45 parts, 48 parts, the content of described Prunus dulcis seed oil is 5 ~ 20 parts, such as 5.2 parts, 5.5 part, 6 parts, 6.5 part, 7 parts, 7.5 part, 8 parts, 9 parts, 10 parts, 11 parts, 12 parts, 13 parts, 15 parts, 17 parts, 19 parts, the content of described Semen Tritici aestivi germ oil is 0.1 ~ 3 part, such as 0.05 part, 0.1 part, 0.15 part, 0.2 part, 0.25 part, 0.3 part, 0.4 part, 0.5 part, 0.8 part, 1 part, 1.1 part, 1.2 part, 1.3 part, 1.5 part, 1.8 part, 2 parts, 2.5 part, 2.8 part, be preferably 0.1 ~ 3 part, by being optimized Oleum Vitis viniferae, Prunus dulcis weight portion that is oily and Semen Tritici aestivi germ oil in base oil, ensureing to make the cost of Weight reducing compound reach minimum while Weight reducing compound has good fat-reducing effect, antiallergic effect.
As preferred version of the present invention, by weight, the described fat-reducing factor is made up of 2 ~ 5 parts of Coffea arabica seed oil, 1 ~ 4 part of campesterol class material and 0.001 ~ 0.1 part of tocopherol.The content of the present invention to each component in the fat-reducing factor is optimized.In the described fat-reducing factor, the weight portion of described Coffea arabica seed oil is 2 ~ 5 parts, such as 2.1 parts, 2.2 parts, 2.5 parts, 2.8 parts, 3 parts, 3.2 parts, 3.5 parts, 3.8 parts, 4 parts, 4.2 parts, 4.5 parts, 4.8 parts; The weight portion of described campesterol class material is 1 ~ 4 part, such as 1.1 parts, 1.2 parts, 1.3 parts, 1.5 parts, 1.8 parts, 2 parts, 2.2 parts, 2.5 parts, 3 parts, 3.5 parts; The weight portion of described tocopherol is 0.001 ~ 0.1 part, such as 0.002 part, 0.005 part, 0.008 part, 0.01 part, 0.02 part, 0.03 part, 0.04 part, 0.05 part, 0.08 part, 0.09 part.
Particularly, described Weight reducing compound also comprises Ginger Root oil; Subcutaneous fat burning can be accelerated after Rhizoma Zingiberis Recens (ZINGIBEROFFICINALE) root oil harmonizes the body, strengthen the metabolism of health, human body is loosened, regulate, relax nervous nerve and the meridian qi and blood etc. that is in harmonious proportion.The present invention adds Ginger Root oil in Weight reducing compound, by regulating meridians, strengthening body metabolism to promote subcutaneous fat cells to decompose and to suppress subcutaneous fat cells differentiation, improves the fat-reducing effect of Weight reducing compound further.
As preferred version of the present invention, by weight, the content of described Ginger Root oil is 20 ~ 40 parts, such as 21 parts, 22 parts, 23 parts, 25 parts, 30 parts, 32 parts, 35 parts, 38 parts.
Particularly, described Weight reducing compound also comprises Pericarpium Citri oil, Pericarpium Citri (CITRUSMEDICALIMONUM) oil is the Pericarpium Citri extract of drying and ripening, Pericarpium Citri oil is containing 35 kinds of compositions, main constituent is limonene (32.0%), citronellal (27.5%), citronellol (13.0%), cymene (6.5%), geranial (2.3%), γ-terpinene (2.0%), citronellic acid (1.8%), alpha-terpineol (1.2%) and linalool (1.2%), Pericarpium Citri oil belongs to Chinese crude drug, there is liver-smoothing, qi-regulating, alleviating distention in middle-JIAO reduces phlegm, effect of profit diaphragm, can be used for treating stagnation of liver-QI and stomach-QI, distending pain in the chest and hypochondrium etc.Usual overweight people often mental pressure is larger, and heart is felt oneself inferior, and accumulates over a long period and is easy to occur the symptoms such as depression of liver-QI, therefore, maximum for the ratio of liver qi stagnation type in overweight people.The present invention adds Pericarpium Citri oil in Weight reducing compound, by treatment depression of liver-QI to improve the fat-reducing effect of Weight reducing compound further.
As preferred version of the present invention, by weight, the content of described Pericarpium Citri oil is 0 ~ 3 part, such as 0.05 part, 0.1 part, 0.15 part, 0.2 part, 0.3 part, 0.4 part, 0.5 part, 0.8 part, 1 part, 1.2 parts, 1.5 parts, 2 parts, 2.5 parts, 2.8 parts, is preferably 0.1 ~ 3 part.
Particularly, contain except tocopherol except in the fat-reducing factor, by weight, described Weight reducing compound also comprises 0.1 ~ 2 part of tocopherol, such as 0.15 part, 0.2 part, 0.3 part, 0.4 part, 0.5 part, 0.8 part, 1 part, 1.2 parts, 1.5 parts, 1.8 parts, 1.9 parts.
As preferred version of the present invention, by weight, described Weight reducing compound also comprises 0 ~ 2 part of Wild soybean oil, such as 0.01 part, 0.05 part, 0.1 part, 0.15 part, 0.2 part, 0.3 part, 0.4 part, 0.5 part, 0.8 part, 1 part, 1.2 parts, 1.5 parts, 1.8 parts, 1.9 parts, be preferably 0.1 ~ 2 part, Wild soybean (GLYCINESOJA) oil is containing precious medicinal ingredients such as soybean isoflavone, soyasaponins, soybean oligo saccharide, soybean phospholipids, and purity reaches more than 90%.The ingredients such as the soybean isoflavone contained in Wild soybean oil, Saponin, to human cytotoxic, treatment cardiovascular and cerebrovascular disease, strengthen body immunity, treatment climacteric syndrome, anti-ageing special medicinal effects of having waited for a long time.Certainly, Wild soybean oil also can be used as the base oil of the above-mentioned fat-reducing factor.
As preferred version of the present invention, in described Weight reducing compound, the described tocopherol except the tocopherol in the fat-reducing factor and the weight ratio of described Wild soybean oil are 1:3 ~ 3:1, are preferably 1:1.On the basis of the above-mentioned fat-reducing factor, add the compositions of tocopherol and Wild soybean oil in Weight reducing compound of the present invention, skin while fat-reducing, can be avoided to produce fold, make skin surface keep smooth.
As preferred version of the present invention, described Weight reducing compound also comprises Fructus Citri sinensis peel oil; Fructus Citri sinensis (CITRUSAURANTIUMDULCIS) peel oil has aging-resistant effect, and directly acting on epidermis and subcutaneous tissue can blood circulation promoting, simultaneously Fructus Citri sinensis peel oil also there is disinfection, effect of pressure of releiving, the intestines and stomach coordinating.The present invention, by adding Fructus Citri sinensis peel oil in above-mentioned Weight reducing compound, by pressure of releiving, the auxiliary fat-reducing of the intestines and stomach coordinating, can extend the shelf-life of Weight reducing compound simultaneously.
As preferred version of the present invention, by weight, the content of described Fructus Citri sinensis peel oil is 0 ~ 1 part, such as 0.01 part, 0.015 part, 0.02 part, 0.025 part, 0.03 part, 0.05 part, 0.08 part, 0.1 part, 0.2 part, 0.3 part, 0.4 part, 0.5 part, 0.6 part, 0.7 part, 0.8 part, 0.9 part, be preferably 0.01 ~ 1 part.
Particularly, described Weight reducing compound also comprises bergamot fruit oil; Bergamot (CITRUSAURANTIUMBERGAMIA) is warm in nature, bitter in the mouth, nontoxic, bergamot fruit oil has the functions such as thin stagnant, stomach invigorating.Modern nutriology research also finds, containing multiple nutritional components such as vitamin B1, vitamin B2, vitamin Cs in bergamot fruit oil, also containing abundant organic acid, citric acid, there is very strong antioxidation, to promoting that the metabolism, consolidation blood capillary, collagen protein generation etc. of skin are very effective.Corruption is there is to prevent Weight reducing compound because of breed bacteria by adding bergamot fruit oil in the present invention, simultaneously by enhancing metabolism the absorption promoting skin to the above-mentioned fat-reducing factor, and produced by consolidation blood capillary, promotion collagen protein, make the skin consolidation after fat-reducing flexible.
As preferred version of the present invention, by weight, the content of described bergamot fruit oil is 0 ~ 3 part, such as 0.01 part, 0.03 part, 0.05 part, 0.1 part, 0.15 part, 0.2 part, 0.3 part, 0.4 part, 0.5 part, 0.8 part, 1 part, 1.2 parts, 1.5 parts, 2 parts, 2.5 parts, 2.8 parts, be preferably 0.1 ~ 3 part.
Particularly, described Weight reducing compound also comprises cedarwood oil; The English name of Cedrus deoclar (Roxb.) G. Don (CEDRUSDEODARA) wood oil is CEDRUSDEODARAWOODOIL, and No. CAS is 91771-47-0.Described cedarwood oil adopts the way of distillation to obtain, and is a kind of liquid of clear yellow viscous, has antibacterial, whitening, antioxidative effect, also has good moisture retention.By adding cedarwood oil in Weight reducing compound of the present invention, can prevent Weight reducing compound from because of breed bacteria, corruption occurring, extending the shelf-life of Weight reducing compound.
As preferred version of the present invention, by weight, the content of described cedarwood oil is 0 ~ 2 part, such as 0.01 part, 0.05 part, 0.1 part, 0.15 part, 0.2 part, 0.3 part, 0.4 part, 0.5 part, 0.8 part, 1 part, 1.2 parts, 1.5 parts, 1.8 parts, is preferably 0.1 ~ 2 part.
Particularly, by weight, described Weight reducing compound also comprises 10 ~ 30 parts of Fructus oleae europaeae fruit oil, such as 11 parts, 12 parts, 13 parts, 15 parts, 18 parts, 20 parts, 22 parts, 25 parts, 28 parts, 29 parts; Fructus oleae europaeae (OLEAEUROPAEA) fruit oil is applied in skin surface and assistant massaging can help fat combustion metabolism, nourishes skin simultaneously, increases gloss and the elasticity of skin, removes fine wrinkles.
Particularly, by weight, described Weight reducing compound also comprises 0 ~ 0.5 part of Herba Rosmarini Officinalis leaf oil, such as 0.01 part, 0.05 part, 0.1 part, 0.15 part, 0.2 part, 0.25 part, 0.3 part, 0.35 part, 0.4 part, 0.45 part, is preferably 0.1 ~ 0.5 part; Herba Rosmarini Officinalis (ROSMARINUSOFFICINALIS) leaf oil extracts from leaf of Herba Rosmarini Officinalis, there is the effect reducing cholesterol and sterilization, be applied in Weight reducing compound and act on skin surface, effectively can reduce cholesterol by massage, its sterilizing function can extend the shelf-life of Weight reducing compound.
As preferred version of the present invention, by weight, described Weight reducing compound also comprises 0 ~ 0.5 part of oil of geranium, such as 0.005 part, 0.01 part, 0.15 part, 0.2 part, 0.25 part, 0.3 part, 0.35 part, 0.4 part, 0.45 part, is preferably 0.01 ~ 0.5 part; Main component in Pelargonium gravelens (PELARGONIUMGRAVEOLENS) oil has Herba Pelargonii Graveolentis grass alcohol, citronellol, linalool etc., for adjustment hormone, to improve premenstrual syndrome very effective, energy Bergamot Mint Extract, blood circulation promoting, makes turgor, has good effect to slack and undisciplined skin, also there is very strong bactericidal effect simultaneously, can extend the shelf-life of Weight reducing compound, in addition, oil of geranium also has the function of strengthening lymphsystem, scavenging free radicals.Oil of geranium adds in above-mentioned Weight reducing compound, is applied in skin surface and massages a period of time, can accelerate subcutaneous fat decomposition rate by blood circulation promoting.
As preferred version of the present invention, by weight, described Weight reducing compound also comprises 0 ~ 0.6 part of Cupressus semperviren wood oil, such as 0.01 part, 0.03 part, 0.05 part, 0.07 part, 0.08 part, 0.09 part, 0.1 part, 0.12 part, 0.15 part, 0.2 part, 0.25 part, 0.3 part, 0.4 part, 0.5 part, be preferably 0.06 ~ 0.6 part; Cupressus sempervirens (CUPRESSUSSEMPERVIRENS) oil, its main component: note alkene (65%, especially beta pinene and terpineol), cedrol, Cedrus deoclar (Roxb.) G. Don Camphora and tannin, Main Function is convergence and skin of releiving, regulates fat secretion, tightens pore, is the optimum selection of moisturizing; All helpful to all over-education phenomenons, particularly restrain, stop blooding, hyperhidrosis, influenza rheumatalgia, edema etc., for greasy, the aged skin of conditioning, promote to scab, reduce weight, moisturizing degree also excellent.Simultaneously can also allaying tiredness, angry emotion of releiving, alleviate heart anxiety and pressure.The present invention, by being applied in Weight reducing compound by Cupressus semperviren wood oil, can promoting that its effect of weight reducing performs to maximum by the fat-reducing factor in Weight reducing compound of the present invention further, repair skin simultaneously.
As preferred version of the present invention, by weight, described Weight reducing compound also comprises 0 ~ 2 part of PEG-20 glyceryl triisostearate, such as 0.01 part, 0.05 part, 0.1 part, 0.15 part, 0.2 part, 0.25 part, 0.3 part, 0.35 part, 0.4 part, 0.5 part, 0.6 part, 0.7 part, 0.8 part, 0.9 part, 1 part, 1.2 parts, 1.5 parts, 1.6 parts, 1.8 parts, be preferably 0.1 ~ 2 part; No. CAS of PEG-20 glyceryl triisostearate is 120486-24-0, it is a kind of faint yellow or yellow viscous liquid, compared with nonionic polyoxyethylene surfactant, PEG-20 stearate shows fabulous oxidation stability and pH stability, compared with sucrose, glycerol, sorbitan ester etc., PEG-20 stearate has fabulous heat stability, PEG-20 stearate is except being used as emulsifying agent, also can be used as emollient, good with the intermiscibility of other oil components, oxidation stability is good.
The present invention also provides a kind of preparation method of Weight reducing compound, and this preparation method comprises following steps:
Coffea arabica seed oil, campesterol class material are mixed with part tocopherol, obtained first mixture, by Wild soybean oil and the mixing of residue tocopherol, obtained second mixture; By base oil, the first mixture, the second mixture, Ginger Root oil, bergamot fruit oil, cedarwood oil, Pericarpium Citri oil, Fructus oleae europaeae fruit oil, Herba Rosmarini Officinalis leaf oil, oil of geranium, Fructus Citri sinensis peel oil, Cupressus semperviren wood oil, PEG-20 glyceryl triisostearate mix homogeneously, filter, obtained described Weight reducing compound;
Preferably, the described Wild soybean oil in described second mixture is 1:3 ~ 3:1 with the weight ratio of described residue tocopherol;
Preferably, described base oil is Oleum Vitis viniferae, Prunus dulcis oil and the mixture of Semen Tritici aestivi germ oil;
In above-mentioned preparation method, the content sum of part tocopherol and residue tocopherol is the total content of tocopherol in the present invention, and the present invention, by being added in two steps by tocopherol, can prevent the first mixture and the second oxide to be oxidized respectively.
As the preferred scheme of the present invention, described preparation method specifically comprises following steps:
2 ~ 5 parts of Coffea arabica seed oil, 1 ~ 4 part of campesterol class material are mixed with 0.001 ~ 0.1 part of tocopherol, obtained first mixture, by 0 ~ 2 part of Wild soybean oil and 0 ~ 2 part of tocopherol mixing, obtained second mixture; By 20 ~ 50 parts of Oleum Vitis viniferaes, 5 ~ 20 parts of Prunus dulcis oil, 0 ~ 3 part of Semen Tritici aestivi germ oil, the first mixture, the second mixture, 20 ~ 40 parts of Ginger Root oil, 0 ~ 3 part of bergamot fruit oil, 0 ~ 2 part of cedarwood oil, 0 ~ 3 part of Pericarpium Citri oil, 10 ~ 30 parts of Fructus oleae europaeae fruit oil, 0 ~ 0.5 part of Herba Rosmarini Officinalis leaf oil, 0 ~ 0.5 part of oil of geranium, 0 ~ 1 part of Fructus Citri sinensis peel oil, 0 ~ 0.5 part of Cupressus semperviren wood oil, 0 ~ 2 part of PEG-20 glyceryl triisostearate mix homogeneously, adopt 1200 order filter-cloth filterings, obtained described Weight reducing compound;
Preferably, the described Wild soybean oil in described second mixture is 1:1 with the weight ratio of described residue tocopherol.
The present invention by above-mentioned preparation method, can obtain fat-reducing effect excellent, use healthy, long shelf-life and the low Weight reducing compound of cost.
In above-mentioned preparation method, the utensil used in each step must be clean, dry, with the germ contamination preventing Weight reducing compound breed bacteria from causing.
Beneficial effect of the present invention: the Coffea arabica seed oil contained in Weight reducing compound of the present invention, campesterol class material and tocopherol, the content reducing SREBP-1 by improving adiposine level reduces lipogenesis and suppresses Adipocyte Differentiation, and the decomposition of fatty tissue is accelerated by activating lipolytic enzyme, thus reach the object of fat-reducing, improved the slackness of skin by the synthesis of stimulation collagen simultaneously, to reach the object of Rosemary Extract, skin surface is made to keep smooth by the estrogen regulating function of tocopherol, the present invention is by Coffea arabica seed oil, campesterol class material and tocopherol Combination application, can work in coordination with and accelerate loss of weight, Firm, glabrous skin.
Detailed description of the invention
Technical scheme of the present invention is further illustrated below by detailed description of the invention.
As no specific instructions, various raw material of the present invention all can commercially availablely be buied, or prepares according to the conventional method of this area.
Embodiment 1
3.9 parts of Coffea arabica seed oil, 2.1 parts of campesterols are mixed with 0.002 part of tocopherol, obtained first mixture, by 0.4 part of Wild soybean oil and 0.4 part of tocopherol mixing, obtained second mixture; 30.37 parts of Oleum Vitis viniferaes, 9 parts of Prunus dulcis oil, 0.5 part of Semen Tritici aestivi germ oil, the first mixture, the second mixture, 30 parts of Ginger Root oil, 1 part of bergamot fruit oil, 0.8 part of cedarwood oil, 0.7 part of Pericarpium Citri oil, 20 parts of Fructus oleae europaeae fruit oil, 0.15 part of Herba Rosmarini Officinalis leaf oil, 0.1 part of oil of geranium, 0.05 part of Fructus Citri sinensis peel oil, 0.03 part of Cupressus semperviren wood oil, 0.5 part of PEG-20 glyceryl triisostearate are placed in clean emulsifying pot, stir at normal temperatures, adopt 1200 order filter-cloth filterings after the assay was approved, obtained described Weight reducing compound.
Embodiment 2
2 parts of Coffea arabica seed oil, 1 part of campesterol are mixed with 0.001 part of tocopherol, obtained first mixture, by 0.75 part of Wild soybean oil and 0.25 part of tocopherol mixing, obtained second mixture; 20.5 parts of Oleum Vitis viniferaes, 5 parts of Prunus dulcis oil, 3 parts of Semen Tritici aestivi germ oils, the first mixture, the second mixture, 20 parts of Ginger Root oil, 0.2 part of bergamot fruit oil, 2 parts of cedarwood oils, 0.1 part of Pericarpium Citri oil, 30 parts of Fructus oleae europaeae fruit oil, 0.5 part of Herba Rosmarini Officinalis leaf oil, 0.3 part of oil of geranium, 0.05 part of Fructus Citri sinensis peel oil, 0.24 part of Cupressus semperviren wood oil, 2 parts of PEG-20 glyceryl triisostearate are placed in clean emulsifying pot, stir at normal temperatures, adopt 1200 order filter-cloth filterings after the assay was approved, obtained described Weight reducing compound.
Embodiment 3
3 parts of Coffea arabica seed oil, 4 parts of campesterols are mixed with 0.06 part of tocopherol, obtained first mixture, by 0.5 part of Wild soybean oil and 1.5 parts of tocopherol mixing, obtained second mixture; 50 parts of Oleum Vitis viniferaes, 5 parts of Prunus dulcis oil, 3 parts of Semen Tritici aestivi germ oils, the first mixture, the second mixture, 40 parts of Ginger Root oil, 3 parts of bergamot fruit oil, 1.8 parts of cedarwood oils, 3 parts of Pericarpium Citri oil, 10 parts of Fructus oleae europaeae fruit oil, 0.1 part of Herba Rosmarini Officinalis leaf oil, 0.5 part of oil of geranium, 0.03 part of Fructus Citri sinensis peel oil, 0.5 part of Cupressus semperviren wood oil, 1 part of PEG-20 glyceryl triisostearate are placed in clean emulsifying pot, stir at normal temperatures, adopt 1200 order filter-cloth filterings after the assay was approved, obtained described Weight reducing compound.
Embodiment 4
5 parts of Coffea arabica seed oil, 2.1 parts of campesterols are mixed with 0.002 part of tocopherol, obtained first mixture, by 0.4 part of Wild soybean oil and 0.4 part of tocopherol mixing, obtained second mixture; 43 parts of Oleum Vitis viniferaes, 18 parts of Prunus dulcis oil, 2 parts of Semen Tritici aestivi germ oils, the first mixture, the second mixture, 30 parts of Ginger Root oil, 1 part of bergamot fruit oil, 0.8 part of cedarwood oil, 0.7 part of Pericarpium Citri oil, 20 parts of Fructus oleae europaeae fruit oil, 0.15 part of Herba Rosmarini Officinalis leaf oil, 0.1 part of oil of geranium, 0.9 part of Fructus Citri sinensis peel oil, 0.5 part of Cupressus semperviren wood oil, 1.85 parts of PEG-20 glyceryl triisostearate are placed in clean emulsifying pot, stir at normal temperatures, adopt 1200 order filter-cloth filterings after the assay was approved, obtained described Weight reducing compound.
Comparative example 1
The fat-reducing factor of the present embodiment adopted 6.002 parts of Coffea arabica seed oil to replace, other are all identical with embodiment 1.
Comparative example 2
The fat-reducing factor of the present embodiment adopted 6.002 parts of campesterols to replace, other are all identical with embodiment 1.
Comparative example 3
The present embodiment does not add the fat-reducing factor, and other are all identical with embodiment 1.
Comparative example 4
The present embodiment does not add Ginger Root oil, and other are all identical with embodiment 1.
Comparative example 5
The present embodiment does not add Fructus Citri peel oil, and other are all identical with embodiment 1.
Comparative example 6
The present embodiment does not add the second mixture, and other are all identical with embodiment 1.
Comparative example 7
The present embodiment is dulcification Fructus Citri junoris haze wax not, and other are all identical with embodiment 1.
In order to verify whether Weight reducing compound of the present invention produces zest to skin, and the sample choosing above-described embodiment 1 is tested.
Method of testing: select 24 female subjects of age between 18 ~ 40 years old, wherein 13 experimenters be sensitivity skin (4 oiliness sensitivity skin, 5 neutral sensitivity skin and 4 dryness sensitivity skin), 11 carry out integrated test for non-sensibility skin (4 oiliness skin, 3 neutral skin and 4 dry skin).The right finesse of experimenter is blank; Get appropriate amount of sample be applied in the left finesse of every experimenter and massaged, treat to absorb completely, every day uses once, uses 28 days continuously, and then carry out contrast scoring, the security test result of sensitivity skin and non-sensibility skin is respectively in table 1, table 2:
Table 1
Table 2
As can be seen from table 1, table 1, adopt sample of the present invention can not produce any stimulation to skin.The security test result of embodiment 2 ~ 4 and comparative example 1 ~ 7 is identical with the secure sample test result of embodiment 1, does not repeat them here.
In order to verify whether Weight reducing compound of the present invention meets hygienic practice, sent by the sample of above-described embodiment 1 ~ 4, comparative example 1 ~ 7 third party authority testing agency to detect, the test result of 11 samples is all as shown in table 3:
Table 3
The result shows, inventive samples meets the monitoring of hygiene standard that GB/T26516-2011 massages quintessence oil.
Human test's fat-reducing effect:
Weight reducing compound is in the using method of abdominal part: (1) is taken a shower or with after hot towel wiping abdominal part, got appropriate sample in the palm of the hand, be flattened on skin of abdomen by finger and palm, the central authorities of the manual massage abdominal part using the parent that slides to comfort and both sides; (2), during oneself massage, the direction along intestinal peristalsis is done significantly clockwise convolution and is rubbed, for other people massage time, be then counterclockwise; (3) by pushing manipulation, poisoning massage is done to abdominal part: both hands are overlapping, exerted a force by hands above, carry out clockwise or be rotated counterclockwise movement.
Weight reducing compound is in the using method of leg: (1) is dripping appropriate Weight reducing compound on hand, counterclockwise massage, impurity and toxin through being deposited on vola are upwards discharged, according to from little sole to medial leg, outside knee again to the order of thigh, with the hands massage; (2) upwards push away and rub muscle inside leg, thumb and all the other four fingers are made V-shaped, upwards rub above the knee till 15 centimetres from inside the leg at ankle position always gently, 6 ~ 10 times repeatedly; (3) beaing leg skin with blood circulation promoting, hold its fist, easily occurring that the knee position of edema beats 5 times, beaing gently from below knee until whole thigh.
330 fat in various degree volunteers are organized to carry out clinical trial, be divided into 12 groups, each group test sample, use weekly Weight reducing compound massage 2 ~ 3 times, adopt tape measuring 330 volunteers respectively before Weight reducing compound uses, use the waistline after 60 days, size that lower limb encloses, calculate the waistline of use after 60 days, reduction size that lower limb encloses, test result is in table 4, table 5.
Table 4
Table 5
Note: lower limb encloses the meansigma methods referring to thigh circumference and calf circumference.
As can be seen from table 4, table 5, when the Coffea arabica seed oil (comparative example 2) not adding the fat-reducing factor (comparative example 3) in Weight reducing compound or only add in the fat-reducing factor or campesterol (comparative example 1), waistline, lower limb enclose average reduce the size Weight reducing compound be less than containing the fat-reducing factor use 60 days after waistline, lower limb enclose and on average reduce size.In addition, adopt respectively far infrared tester test 330 volunteers before Weight reducing compound uses, use the degree of packing of the waist after 60 days, leg skin, result shows the improvement (not shown in table) of about 15%.
As can be seen from above-mentioned table 4, table 5, for not containing Ginger Root oil (comparative example 4), not containing Pericarpium Citri oil (comparative example 5), do not add tocopherol and Wild soybean fluid composition (comparative example 6) or not containing the Weight reducing compound of Fructus Citri sinensis peel oil (comparative example 7), in the test of its fat-reducing effect, the average reduction size that waistline, lower limb enclose is relatively little.
In sum, Weight reducing compound of the present invention has good fat-reducing effect, and volunteer after 60 days, can reduce its waistline at use Weight reducing compound of the present invention to a certain extent, lower limb encloses size and strengthens the degree of packing of its waist, leg skin.
Certainly, only add Oleum Vitis viniferae, Prunus dulcis oil, Ginger Root oil, Fructus oleae europaeae fruit oil, Coffea arabica seed oil, campesterol and tocopherol time, the obtained breast enlargement effect of breast enlargement compositions and the effect of the breast enlargement compositions of comparative example 6 closely, do not repeat them here.
Also can have auxiliary fat-reducing effect to a certain degree for other Some essential oils in the present invention, not repeat them here.
Above embodiment is only used for method detailed of the present invention is described, the present invention is not limited to above-mentioned method detailed, does not namely mean that the present invention must rely on above-mentioned method detailed and could implement.Person of ordinary skill in the field should understand, any improvement in the present invention, to equivalence replacement and the interpolation of auxiliary element, the concrete way choice etc. of each raw material of product of the present invention, all drops within protection scope of the present invention and open scope.
Claims (10)
1. a Weight reducing compound, is characterized in that, comprises base oil and is scattered in the fat-reducing factor in described base oil, and the described fat-reducing factor is the mixture of Coffea arabica seed oil, campesterol class material and tocopherol.
2. Weight reducing compound according to claim 1, is characterized in that, described base oil is Oleum Vitis viniferae, Prunus dulcis oil and the mixture of Semen Tritici aestivi germ oil;
Preferably, by weight, described base oil comprises 20 ~ 50 parts of Oleum Vitis viniferaes, 5 ~ 20 parts of Prunus dulcis seed oil and 0 ~ 3 part of Semen Tritici aestivi germ oil;
Preferably, by weight, the described fat-reducing factor is made up of 2 ~ 5 parts of Coffea arabica seed oil, 1 ~ 4 part of campesterol class material and 0.001 ~ 0.1 part of tocopherol.
3. Weight reducing compound according to claim 1, is characterized in that, described Weight reducing compound also comprises Ginger Root oil;
Preferably, by weight, the content of described Ginger Root oil is 20 ~ 40 parts.
4. Weight reducing compound according to claim 1, is characterized in that, described Weight reducing compound also comprises Pericarpium Citri oil;
Preferably, by weight, the content of described Pericarpium Citri oil is 0 ~ 3 part.
5. Weight reducing compound according to claim 1, is characterized in that, contain except tocopherol except in the fat-reducing factor, by weight, described Weight reducing compound also comprises 0 ~ 2 part of tocopherol;
Preferably, by weight, described Weight reducing compound also comprises 0 ~ 2 part of Wild soybean oil;
Preferably, in described Weight reducing compound, the described tocopherol except the tocopherol in the fat-reducing factor and the weight ratio of described Wild soybean oil are 1:3 ~ 3:1, are preferably 1:1.
6. Weight reducing compound according to claim 1, is characterized in that, described Weight reducing compound also comprises Fructus Citri sinensis peel oil;
Preferably, by weight, the content of described Fructus Citri sinensis peel oil is 0 ~ 1 part.
7. Weight reducing compound according to claim 1, is characterized in that, described Weight reducing compound also comprises bergamot fruit oil;
Preferably, by weight, the content of described bergamot fruit oil is 0 ~ 3 part.
8. Weight reducing compound according to claim 1, is characterized in that, described Weight reducing compound also comprises cedarwood oil;
Preferably, by weight, the content of described cedarwood oil is 0.1 ~ 2 part.
9. Weight reducing compound according to claim 1, is characterized in that, by weight, described Weight reducing compound also comprises 10 ~ 30 parts of Fructus oleae europaeae fruit oil;
Preferably, by weight, described Weight reducing compound also comprises 0 ~ 0.5 part of Herba Rosmarini Officinalis leaf oil;
Preferably, by weight, described Weight reducing compound also comprises 0 ~ 0.5 part of oil of geranium;
Preferably, by weight, described Weight reducing compound also comprises 0 ~ 0.5 part of Cupressus semperviren wood oil;
Preferably, by weight, described Weight reducing compound also comprises 0 ~ 2 part of PEG-20 glyceryl triisostearate.
10. a preparation method for the Weight reducing compound described in any one of claim 1 to 9, is characterized in that, comprises following steps:
Coffea arabica seed oil, campesterol class material are mixed with part tocopherol, obtained first mixture, by Wild soybean oil and the mixing of residue tocopherol, obtained second mixture; By base oil, the first mixture, the second mixture, Ginger Root oil, bergamot fruit oil, cedarwood oil, Pericarpium Citri oil, Fructus oleae europaeae fruit oil, Herba Rosmarini Officinalis leaf oil, oil of geranium, Fructus Citri sinensis peel oil, Cupressus semperviren wood oil, PEG-20 glyceryl triisostearate mix homogeneously, filter, obtained described Weight reducing compound;
Preferably, the described Wild soybean oil in described second mixture is 1:3 ~ 3:1 with the weight ratio of described residue tocopherol;
Preferably, described base oil is Oleum Vitis viniferae, Prunus dulcis oil and the mixture of Semen Tritici aestivi germ oil;
Preferably, described preparation method specifically comprises following steps:
2 ~ 5 parts of Coffea arabica seed oil, 1 ~ 4 part of campesterol class material are mixed with 0.001 ~ 0.1 part of tocopherol, obtained first mixture, by 0 ~ 2 part of Wild soybean oil and 0 ~ 2 part of tocopherol mixing, obtained second mixture; By 20 ~ 50 parts of Oleum Vitis viniferaes, 5 ~ 20 parts of Prunus dulcis oil, 0 ~ 3 part of Semen Tritici aestivi germ oil, the first mixture, the second mixture, 20 ~ 40 parts of Ginger Root oil, 0 ~ 3 part of bergamot fruit oil, 0 ~ 2 part of cedarwood oil, 0 ~ 3 part of Pericarpium Citri oil, 10 ~ 30 parts of Fructus oleae europaeae fruit oil, 0 ~ 0.5 part of Herba Rosmarini Officinalis leaf oil, 0 ~ 0.5 part of oil of geranium, 0 ~ 1 part of Fructus Citri sinensis peel oil, 0 ~ 0.5 part of Cupressus semperviren wood oil, 0 ~ 2 part of PEG-20 glyceryl triisostearate mix homogeneously, adopt 1200 order filter-cloth filterings, obtained described Weight reducing compound;
Preferably, the described Wild soybean oil in described second mixture is 1:1 with the weight ratio of described residue tocopherol.
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