KR20130073579A - Composition for improving condition of skin and scalp containing fermented extracts of herb mixture - Google Patents

Abstract

PURPOSE: A composition containing a fermented natural product complex extract for improving skin and scalp conditions is provided to treat skin diseases without skin irritation, and to increase inherent regeneration ability. CONSTITUTION: A fermented natural product complex extract which improves skin and scalp conditions is prepared by: mixing and extracting one or more among Sanguisorba officinalis L., Solanum nigrum, Rumex coreanus NAKAI, Lufa cylindrical, pine needles, sea mustard, soybean, Zanthoxylum piperitum DC, and bamboo sap in a weight ratio of 1-30:1-10:1-10:1-10:1-30:1-10:1-10:1-10:1-10; inoculating lactic acid bacteria and yeast; and fermenting. The lactic acid bacteria are selected from the group consisting of Lactobacillus sp., Streptococcus sp., Pediococcus sp., Leuconostoc sp., and Bifidobacterium sp. [Reference numerals] (AA) Before use; (BB) After use

Description

COMPOSITION FOR IMPROVING CONDITION OF SKIN AND SCALP CONTAINING FERMENTED EXTRACTS OF HERB MIXTURE}

The present invention relates to a composition for improving the condition of skin and scalp using the natural complex fermented extract as an active ingredient, and more specifically, the skin consisting of cucumber grass, yam, sprout, loofah, pine needles, seaweed, soybean, sancho and bamboo sap And it relates to a natural product composite fermentation extract having a scalp condition and a method for producing the same, and a composition for improving skin and scalp condition using the extract as an active ingredient.

As the quality of life gets higher, many diseases appear to be unknown to modern people. The main causes are stress and environmental pollution. While the development of scientific and mechanical civilization is convenient, it leads to our survival problems, which leads to disease and loss of immunity.

The stress of the modern man can break the rhythm of the body and cause problems of the circulatory system, which can lead to the problem of the state of health, and also appear as a side effect on the appearance of the skin.

Dermatitis or scalp inflammation is caused by physical problems such as excessive sebum production due to abnormal sensitization of skin to various contaminants, bacteria, endocrine system, autonomic nervous system disorders, circulatory disorders such as blood circulation disorders, malnutrition of hair roots, allergies, bacterial infections, etc. Factors, genetic factors such as hormonal effects, environmental factors such as the use of various pollutions and processed foods, shampoos, soaps, mousses, hair gels, hairsprays, perms, dyes, hair dryers and detergents It is known that the psychological, social factors, and aging of modern people who are frequently stressed appear in combination. In recent years, various skin diseases have been increasing regardless of age or gender.

Topical coatings, oral dosages, dietary supplements, and injection drug treatments are being used to treat such skin or scalp diseases. However, the methods described above are limited in scope of use, and may develop into chronic diseases due to repetitive dermatitis or scalp diseases, and the effects of drug treatment are often temporary.

In addition, in the case of skin diseases, resistance is difficult to treat, scalp rather accelerates the production of sebum, and skin diseases, especially heart disease patients with adverse effects such as adverse effects such as adverse effects.

After all, the present invention was devised to solve the above problems, the main object of the present invention is not only the effect of preventing the inflammation of the skin and scalp, but also a natural complex fermented extract that can improve the skin and scalp condition active ingredient It is to provide a composition for improving skin and scalp conditions.

In order to achieve the above object, the present invention provides a natural product complex fermentation extract having an effect of improving the skin and scalp condition.

In the present invention, the natural product complex fermentation extract is mixed with any one or more selected from cucumber grass, walrus, russetula, loofah, pine needles, seaweed, soybean, sancho, and bamboo sap, water, lower alcohol having 1 to 4 carbon atoms or After extracting them with a mixed solvent, the extract is fermented by inoculating lactic acid bacteria or yeast, characterized in that the cucumber grass, black yam, russetula, loofah, pine needles, seaweed, soybeans, sancho, and bamboo sap each 1 ~ 30: 1 ~ 10: 1 ~ 10: 1 ~ 10: 1 ~ 30: 1 ~ 10: 1 ~ 10: 1 ~ 10: It is good to mix in a weight ratio of 1 to 10.

In addition, the present invention provides a method for producing the natural product complex fermentation extract.

The present invention also provides a composition for improving skin and scalp conditions using the natural product complex fermentation extract as an active ingredient.

For reference, this application was performed as a technical support project of Daegu Techno Park Hanban One Center.

According to the present invention as described above, the effects of extracts derived from natural products can safely improve the skin disease without skin irritation, and to relieve inflammation, itching, etc. by cell regeneration to stabilize the skin hypersensitivity reactions, so symptoms are temporarily Rather than improving it, it is possible to treat the fundamental treatment that focuses on increasing the natural regeneration of the skin.

In addition, the natural complex fermented extract of the present invention is effective in preventing atopic dermatitis, allergy, athlete's foot, psoriasis, acne, seborrheic dermatitis, itching, hair loss, hair growth, dandruff suppression, scalp inflammation, skin, hair and scalp prevention, treatment and It can be usefully used for skin treatments, moisturizers, skin cleaners, scalp cleaners, dandruff treatments, cosmetics, health foods for improvement.

1 is a photograph showing the state before and after 3 months of use of the natural product complex fermentation extract of the present invention to the test subjects with symptoms of dermatitis in the hand.
Figure 2 is a photograph showing the state before and after 3 months of use of the natural product complex fermentation extract of the present invention to subjects with seborrheic alopecia.
Figure 3 is a photograph showing the state before and after using the natural compound fermented extract of the present invention 1 month and 3 months to test subjects who are hospitalized with allergic symptoms.

Hereinafter, the present invention will be described in detail.

The present invention provides a complex fermentation extract derived from natural products having an effect of improving skin and scalp conditions.

In the present invention, the natural product complex fermentation extract is preferably any one or more selected from cucumber grass, black seaweed, scallop, loofah, pine needles, seaweed, soybeans, sancho, and bamboo sap, the cucumber grass, black seaweed, slush, loofah , Pine needles, seaweed, soybeans, sancho, and bamboo sap respectively 1-30: 1-10: 1-10: 1-10: 1-30: 1-10: 1-10: 1-10: 1-10 Optimum effect is obtained when mixed in weight ratio.

The sample selected as above is about 1 to 20 times the powder weight, preferably 5 to 15 times water, lower alcohol having 1 to 4 carbon atoms or a mixed solvent thereof, preferably 35 to 120 ° C. after powdering. Preferably, using an extraction method such as stirring extraction, hot water extraction, cold extraction, warm extraction, reflux cooling extraction or ultrasonic extraction for about 0.1 to 48 hours, preferably 1 to 24 hours at 95 to 100 ℃ Preferably, after extracting hot water, the obtained extract is filtered, concentrated or dried to obtain an extract.

In the present invention, the 'extract' includes all extracts, purified products, diluents, concentrates, and dried products, the extract obtained as described above is inoculated at least one of lactic acid bacteria and yeast fermented at 24 ~ 72 hours at 30 ~ 50 ℃ It is preferable to make it.

Lactic acid bacteria that can be used in the present invention is Lactobacillus genus of lactic acid bacteria (Lactobacillus sp.), Streptococcus genus of lactic acid bacteria (Streptococcus sp.), Phedi OKO kusu in lactic acid bacteria (Pediococcus sp.), Flow Pocono stock in lactic acid (Leuconostoc sp.) And It may be one or more strains selected from the group consisting of Bifidobacterium sp. In addition, the yeast includes Saccharomyces sereviciae , Saccharomyces rouxii , Saccharomyces oviformis , Saccharomyces steineri Etc. are included. Preferably, Lactobacillus paracasei may be used as the lactic acid bacterium.

However, the type of the strain or yeast is selected in consideration of the human stability and fermentation power, so that the composition according to the present invention is applied directly to the human body in the form of external preparations for skin, etc., used in the art as long as human stability and fermentation power are recognized. Any strain or yeast may be used, the present invention is not limited to the type of lactic acid bacteria and yeast.

In addition, the term 'improvement of skin and scalp' in the present invention means improvement of the condition of all skin, scalp and hair classified as skin and scalp disease or symptom in the art except severe scars, preferably atopic dermatitis, allergic Treatment of skin and scalp diseases or symptoms of one or more of dermatitis, burns, athlete's foot, contact dermatitis, dandruff, alopecia areata, seborrheic dermatitis, psoriasis, or scleroderma, female alopecia, and pediatric alopecia And improvements.

Cucumber (Sanguisorba officinalis L) used in the present invention is a perennial herb belonging to the family Rosaceae, and is named after the smell of cucumbers in plants. Usually, the root is used as a medicine, and it is used for convergence, fever, diarrhea, dysentery, hemostasis, excessive menstruation, hemoptysis, skin disease, wounds and burns and lacerations. In addition, the root contains 17% of tannins and saponins, and the leaves contain a lot of trace elements such as carbohydrates, proteins, fats, minerals, calcium, iron, copper, and zinc. It is good to eat with fresh juice.

In addition, Solanum nigrum L is an annual herb that is accorded to the branch family, and small white flowers bloom in summer and ripe in the fall. The fruit is succulent, so children eat and young leaves are eaten as herbs. These crows have long been commonly used as medicines for treating carbuncles, boils and spears.In ancient Chinese medicine books such as `` Tangbon Herb '', `` Tokyo Herb '', and `` Horum Herb '', the crow middle heats up and peees well. It is said to help rejuvenate, sleep less, control poisons, bruises, fish blood, and detoxify various minerals. It is also one of the strongest anti-cancer medicines and is widely used as a cancer treatment. It removes inflammation, kills all kinds of bacteria, stops coughing, and releases the poison accumulated in the body. In addition, the atropine component contained in the fruit makes the pupils larger, which helps myopia patients caused by paralysis of the ocular osteotomy muscles.

In addition, Rumex crispus L is another name also known as solbanggi, songguji, young leaves are also eaten as herbs. In addition, it is effective in ringworm, athlete's foot, eczema, etc. Since ancient times, it has been used in the general public for skin diseases such as improvement, scabies and skin cancer. The roots are cut in the autumn and dried in the sun, which is called Yangje-geun, and it is used as a substitute for rhubarb. High doses can cause side effects such as diarrhea.

In addition, scrub (Luffa cylindrica R) is known to be effective in improving rhinitis, making breast milk well, preventing fifty shoulders, enteritis, and atopic dermatitis.

In addition, pine needles (Pinus densflora) contains a lot of sugar, especially protein, fat, calcium, phosphorus, iron, vitamins A, C and the like. Pine needles lower the cholesterol levels in the body and expand the peripheral nerves to increase the secretion of hormones, thereby stimulating the body's tissues.It is effective in hypertension, myocardial infarction, and stabilizes nerves. Great help In addition, pine needles contain glycokinin, a substance that lowers plasma, which helps diabetes, and is rich in vitamin C and iron, which is good for anemia. It is also used in bruises, insomnia, edema, and skin diseases.

In addition, seaweed (Undaria pinnatifida Harvey Suringar) is a strong alkaline food containing a large amount of calcium, alginic acid, laminarin, fucoidan, folksterol, chlorophyll, EPA (eicosapentaenoic acid), DHA (Docosa Hexaenoic Acid), linoleic acid, vitamin A Is rich in B1, B2 and mannitol. It is widely used as a coercive agent to lower blood pressure without any side effect and is known to have anticancer action, anticoagulant action and detoxification effect.

In addition, the beans (Fabaceae) is evaluated as an excellent effect not only as food, but also as a health food, it plays a role in preventing adult diseases, promoting blood circulation and maintaining the balance of hormones. In addition, the beans have an anti-cancer effect, in the 'consent bogam' the long-term use of soybeans have the effect of seeing, gaining weight, removing the heat of the stomach, intestinal pain, heat poisoning, control the excretion of urine, edema And abdominal bloating. On the other hand, kongkaru also controls the stomach and intestines, helps to digest grains and removes boils, and bean sprouts are said to control knee pain and eliminate muscle pain.

In addition, Sancho (Zanthoxylum schinifolium Siebold) is also called cheoncho, herb, Yacho, Hangcho oil, branch tree, Bundi tree, hyacinth, vinegar, inflorescence, etc. It is eaten together with jangchae, and the fruit is squeezed out and is widely used as lighting and flavoring. It is effective for mastitis and boils, bruises, hemorrhoids, headaches and coughs, eliminating extremity pain (四肢 膝痛), is also good for wind and wet rain (風 寒濕 痺). In addition, it is effective in hypertension, anticancer, tonic, capillary expansion and the like.

Bamboo, stem, epidermis, bamboo shoots, and bamboo shoots were used for the treatment of diseases, but bamboo sap (Bam busoideae) is known to be effective in suppressing the occurrence of dry stomach, diuresis, neurostable and heart disease.

The present invention also provides a composition for improving skin and scalp condition using the complex fermented extract derived from the natural product as an active ingredient.

In addition, the composition of the present invention may include the natural product fermentation extract in any amount within the range that does not have toxicity to the human body depending on the degree of symptoms and use of the skin and scalp, specifically based on the total weight of the composition It may be included in 0.001 to 99.99% by weight, preferably 0.1 to 50% by weight.

In addition, the compositions of the present invention further contain a pharmaceutically or cosmetically acceptable carrier, and include conventional creams, lotions, tonics, sprays, aerosols, oils, solutions, suspensions, gels, ointments, emulsions, sesame seeds, pastes and the like. It may be prepared in a phosphorus formulation. The composition of this invention contains a conventional base, and the other component generally used as a pharmaceutical or cosmetic raw material can be mix | blended suitably as needed.

The base of the composition of the present invention can be used as long as it is commonly used, such as purified water, mineral water, ethanol, glycerin, squalene, 1,3-propylene glycol, 1,3-butylene glycol, castor oil, Tsubaki Oils and liquid petrolatum. Examples of other components to be incorporated into the compositions of the present invention include, but are not limited to, surfactants, emulsifiers, thickeners, preservatives (eg, methyl paraoxybenzoate), antioxidants, fragrances, and the like.

In addition to the above components, the composition of the present invention may include components that may serve to supply nutrients to hair follicles or hair growth promoting auxiliary components that are commonly used. For example, vitamins, amino acids, animal and vegetable oils, sodium chloride And the like, but are not limited thereto. These amounts are preferably added at 0.0001 to 10% by weight, preferably 0.01 to 1% by weight of the total composition. In this case, the vitamins include all but not limited to vitamin A, vitamin B1, vitamin B2, niacin (nicotinic acid), vitamin C, vitamin E, sodium pantothenate, potassium pantothenate, biotin H (vitamin H), and the like, amino acids The class includes, but is not limited to, waveguides. In addition, animal and vegetable oils include, but are not limited to, horse oil, egg oil, olive oil, camellia oil, rapeseed oil, sesame oil, germ oil, and the like.

The compositions of the present invention can be used by methods such as direct application or spreading on the skin, hair and scalp.

In the present invention, the term "hair" includes hair follicles and hair follicles of hair, hair and eyelashes, and eyelashes, beards, armpits, pubic hair, and all parts having hair roots and hair follicles throughout the body. Accordingly, the present invention provides hair tonics, hair lotions, hair creams, hair sprays, hair mousses, hair gels, hair conditioners, hair shampoos, hair rinses, hair packs, hair treatments, eyebrow regrowths, eyelash regrowths or eyelash nutrients, or pets. It can be used as a shampoo and pet rinse.

The dosage of the composition according to the present invention should be appropriately determined in consideration of sex, age, symptoms, skin and scalp conditions, and the like. Preferably it can be applied 1 to 5 times 3 ~ 15 추출물 1 day extract based on the adult.

When the composition of the present invention is applied to a patient with the most refractory dermatitis, dermatitis is remarkably reduced after 1 to 4 weeks, and returned to almost normal level after 4 to 12 weeks.

In addition, the bactericidal effect was also excellent against dandruff seborrheic dermatitis, and when applied to a patient with seborrheic alopecia, it was confirmed that after 3 months, the hair regeneration was simultaneously improved and the hair loss was cured. Therefore, the composition of the present invention can be used for hair loss preventing agent, hair growth promoting agent, hair growth agent, scalp cleaner, dandruff treatment agent and the like.

Hereinafter, the present invention will be described in more detail with reference to Examples. It is to be understood by those skilled in the art that these examples are for illustrative purposes only and that the scope of the present invention is not construed as being limited by these examples.

Example. Preparation of complex fermented extract derived from natural products

Cucumbers, black walnuts, scallops, scrubbers, pine needles, seaweed, soybeans, sancho and bamboo sap, which are commercially available, are sterilized well and then each powdered and then sterilized 10: 5: 5: 5: 10: 5: 5: 3: After mixing at a weight ratio of 2, 500 g was taken from the mixed powder, and 6 L of water was added thereto, followed by extraction at 95 to 100 ° C for 24 hours.

The extract was sterilized after filtration, and fermented for 72 hours (3 days) while maintaining 35-40 ° C. by adding lactic acid bacteria ( Lactobacillus paracasei KW3110) to the sterilized extract at a concentration of 10 mg strain per 100 mg of extract. An extract was prepared.

Experimental Example 1. Confirmation of improvement of skin condition (1)

For 11 people with symptoms of dermatitis on their hands, 3 ~ 5 times a day of the natural product complex fermentation extract of about 3 하여 per time, and evenly spreading a total of 9 ~ 15 하루 a day by tapping the first month The results were observed after 3 months of use.

Experimental Example 2. Confirmation of improvement of scalp condition

To 20 people with severe seborrheic alopecia, towel dry after shampooing 3 to 5 times a day using 3 ㏄ once a day, and evenly spread the scalp from 9 to 15 에 evenly on the scalp where the natural product fermentation extract prepared in Example After the first one to three months using a method of massage and massage, the results were observed.

Experimental Example 3. Confirmation of improvement of skin condition (2)

For 17 patients hospitalized with allergies to the hospital, the natural product complex fermentation extract prepared in the above example was used by tapping evenly in an amount of 9-15 회 3 to 5 times a day by using 3 당 per dose. The results were observed after 3 months of use.

As a result, as shown in Figures 1 to 3, all the subjects were significantly reduced symptoms and skin and scalp condition improvement effect was confirmed, there was no skin irritation or side effects during the experiment.

Having described specific portions of the present invention in detail, those skilled in the art will appreciate that these specific descriptions are only for the preferred embodiment and that the scope of the present invention is not limited thereby. It will be obvious. Accordingly, the actual scope of the present invention will be defined by the appended claims and their equivalents.

Claims (8)

After extracting any one or more selected from a cucumber grass, yam, slush, loofah, pine needles, seaweed, soybeans, sancho, and bamboo sap, and inoculated one or more of lactic acid bacteria and yeast into the extract is characterized in that it is produced by fermentation Natural product complex fermented extract having the effect of improving skin and scalp condition.
The method of claim 1,
The extract is cucumber grass, black yam, slush, loofah, pine needles, seaweed, soybeans, sancho, and bamboo sap, respectively 1-30: 1-10: 1-10: 1-10: 1-30: 1-10: 1 ~ 10: 1 ~ 10: natural product complex fermentation extract, characterized in that consisting of a weight ratio of 1 to 10.
The method of claim 1,
The lactobacillus is Lactobacillus sp., Lactobacillus sp., Streptococcus sp., Pediococcus sp., Pediococcus sp., Leuconostoc sp. Natural product complex fermentation extract, characterized in that at least one strain selected from the group consisting of Bifidobacterium sp.
A composition for improving skin and scalp conditions using the natural complex fermented extract of any one of claims 1 to 3 as an active ingredient.
5. The method of claim 4,
The composition is directed to improving skin and scalp conditions including any one or more of the symptoms of atopic dermatitis, allergic dermatitis, burns, athlete's foot, contact dermatitis, dandruff, alopecia areata, seborrheic dermatitis, psoriasis, scalp inflammation, and seborrheic hair loss. A composition for improving skin and scalp conditions.
(1) Cucumbers, buckwheat, broccoli, loofah, pine needles, seaweed, soybeans, sancho, and bamboo sap, respectively, 1-30: 1-10: 1-10: 1-10: 1-30: 1-10: 1 ˜10: 1 to 10: 1 mixing at a weight ratio of 1 to 10;
(2) powdering the mixture and extracting it with water, a lower alcohol having 1 to 4 carbon atoms, or a mixed solvent thereof;
(3) inoculating one or more of lactic acid bacteria and yeast after filtering the extract;
The method according to claim 6,
The lactic acid bacteria Lactobacillus paracasei ( Lactobacillus paracasei KW3110) characterized in that the natural product complex fermentation extract manufacturing method.
The method according to claim 6,
The fermentation is a natural product complex fermentation extract manufacturing method, characterized in that the fermentation for 30 to 50 hours at 30 ~ 50 ℃.

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