KR20110062214A - Composition for improving atopic dermatitis and the manufacturing method thereof - Google Patents

Abstract

PURPOSE: A functional composition containing medicinal herb concentrate is provided to relieve atopic dermatitis. CONSTITUTION: A functional composition for relieving atopic dermatitis contains 50 weight% of natural medicinal extract, 30 weight% of herb extract, and 20 weight% of grain extract which are concentrated with alkali water, naturally fermented, and performed by nanomethod. The natural medicinal extract is prepared by isolating each 5 weight% of medicinal herbs(Angelicae gigantis Radix, Paeoniae Radix, wild mulberry leaf, Lycii Fructus, Glycyrrhizae radix, pine needles, green tea, Houttuynia cordata, Corni Fructus, jujube). The herb extract is isolated using 10 weight% of chamomile, 10 weight% of rooibos, and 10 weight% of lavender.

Description

Functional composition for atopic dermatitis alleviation and its manufacturing method {COMPOSITION FOR IMPROVING ATOPIC DERMATITIS AND THE MANUFACTURING METHOD THEREOF}

The present invention relates to a composition for improving atopic dermatitis, and functional composition for alleviating atopic dermatitis for relieving atopic dermatitis applied to the skin by instantaneous absorption of the mixed composition of herbal concentrates into the dermal dermal layer using a nanotechnology method. And a method for producing the same.

The term atopy means "weird" or "inappropriate," and the reality is that the etymology of atopy does not pinpoint the cause of the disease, as it comes from an unknown meaning. However, from the time of atopic development, the biggest problem is considered to be the biggest cause of changes in diet, pollution of environmental air, and ingestion of numerous harmful substances.

Severe injuries of atopy are a kind of skin allergen reaction, such as skin dryness and eczema. 40% of children suffer from atopy symptoms.

Atopic dermatitis, also known as fever, is accompanied by chronic diseases of the skin, as well as allergic diseases such as hay fever. This disease is called allergic eczema, pediatric eczema, ectopic eczema, pancreatic neurodermatitis, etc., and is a clinical category of clinical and histological processes that show progression from infant eczema to typical thyroid dermatitis in boys, puberty, and adults. .

Atopic dermatitis is a chronic relapsing eczema disease, the cause and pathogenesis of which are not clear. It is now understood that atopic dermatitis is mainly caused by a unique genetic predisposition, but its cause is not simple and is caused by a multi-factorial.

Considering these symptoms, atopy plays a role of protecting skin from harmful environment, enhancing its own immunity and increasing antioxidant effect, removing harmful radical oxygen, improving skin moisturizing ability, reducing skin irritation as much as possible, and protecting against irritation. Dermatitis alleviators are needed.

Accordingly, an object of the present invention is to provide a functional composition for alleviating atopic dermatitis and a method for producing the same, which can increase moisturizing power and block harmful irritants.

Another object of the present invention is to provide a functional composition for alleviating atopic dermatitis and a method for producing the same, which has no irritation to the skin and can release antioxidant and anti-inflammatory and skin toxins.

Functional composition for atopic dermatitis mitigation of the present invention for achieving this purpose is concentrated by alkaline water and 50% by weight of natural herbal extracts, 30% by weight of herbal extracts, and 20% by weight of grain extracts are formulated by nanotechnology.

And, in order to achieve the object of the present invention a method for preparing atopic dermatitis functional composition for a) the step of replacing the rock water with alkaline ionized water using natural ore, b) extracting the natural herbal components, c) herb components Tinting and extracting, d) extracting the grains, e) concentrating the extract of steps b) to d) again with alkaline ionized water produced in step a) and f) step e) The concentrated mixture of can be made by the step of natural natural fermentation using yeast and baekbaekpi.

The alkaline water is produced by replacing the rock water with alkaline ionized water using silicon and biotite, and the natural herbal extracts are 5% by weight of each of the 10 herbal components (Dang Quai, Peony, Wild Leaf, Gojiberry, Licorice, Pine Needle, Green Tea, Echo , Cornus and jujube).

In addition, the herbal extract is extracted by tincture with 10% by weight of chamomile, 10% by weight of rooibos, and 10% by weight of lavender, and the grain extract is extracted with 10% by weight of black bean and 10% by weight of barley rice, natural fermentation to the alkaline water The concentrated mixture is characterized in that the fermentation using yeast and lettuce.

Therefore, according to the functional composition for atopic dermatitis mitigation of the present invention, natural mixed-fermentation of herbal concentrates and natural absorption of the skin to the dermis using the instantaneous method to relieve atopic dermatitis applied to the skin to increase the moisturizing power and harmful Has the effect of blocking irritants,

In addition, there is no skin irritation and has the effect of releasing antioxidant and anti-inflammatory and skin toxin.

The terms or words used in this specification and claims are not to be construed as limiting in their usual or dictionary meanings, and the inventors may properly define the concept of terms in order to best explain their invention in the best way possible. It should be interpreted as meaning and concept corresponding to the technical idea of the present invention.

The term herbal medicine used in the present invention means to use as a component having a beneficial effect on the human body by processing such as natural or naturally produced natural products as it is, dried, sliced, heated, extracted or powdered, and If the natural product from which the herbal medicine is obtained is a plant, it can be classified as a vegetable herbal medicine, a mineral mineral herbal medicine, and an animal animal herbal medicine.

First, various components used in the composition for relieving atopic dermatitis of the present invention are well known in the art, and Angelica, peony, wild mulberry leaves, wolfberry, licorice, pine needles, green tea, eoseongcho, cornus oil, jujube, etc. are purchased on the market as natural foods. It's easy and you can easily buy herbal ingredients such as chamomile, rooibos, and lavender.

At this time, the herbal ingredients may use a general product, but it is preferable to prepare by selecting and washing only domestic products without residual pesticides.

Angelica is sweet and filling, its nature is warm, and Angelica belonging to the apiaceae is used for drying its roots. It contains essential oils containing coumarin, such as tecursin, nodakenetine, and nodakenin. It is used as a stationary part of inflammation treatment, and it is effective for skin disease, which is a symptom of blood vessels or hematopoietic wind, and has a good effect on burcellosis, an allergic onset that occurs slowly.

Peony has the effects of analgesic, fever, jingyeong, diuresis, hematopoiesis, cold, etc. abdominal pain, stomach pain, headache, diarrhea abdominal pain, rheumatoid arthritis, dysmenorrhea, dysmenorrhea, symptom, cold sweat, body Write on weakness. In addition, as a cosmetic raw material is known to have a variety of efficacy and effects to suppress skin whitening and antioxidant itching.

Mountain mulberry leaves are the second most protein-rich foods in plants, and are rich in calcium, potassium, and plant fiber. Shin Nongbonchocho (農 神 草 經) removes heat and sweat.In Ilhwaboncho (日 華 本草), if you drink mulberry leaves with tea, it benefits the five intestines, passes through the joints, and lowers the weak leaves. mother

It is said to control all winds, and it is effective in alleviating constipation and diet as well as treating and preventing various adult diseases.

Goji berries are the fruits of goji berry, a deciduous shrub of the dicotyledon plant moss. It contains protein, fat, sugar, calcium, phosphorus, iron, betaine, rutin, and vitamins (A, B 1, B2, C). Is fast. In oriental medicine, it is used as a tonic and antipyretic. It is known to improve vision, prevent adult diseases such as diabetes, improve lung and kidney function, and produce immune enhancing substances.

Licorice is a plant distributed in northeastern China, Siberia and Mongolia. It is widely used for medicinal purposes in the East and West. Licorice root extract contains ingredients such as Glycyrrhizin, saponins, asparagine, sugarss, resin, etc. Among them, glycyrrhizin and glycyrrhetinic acid are the main ingredients for cell regeneration, sedation, anti-inflammatory, antioxidant, whitening, skin metabolism It is said to be excellent for promotion.

Pine needles have bactericidal action, anti-inflammatory action by the live pine terebin, and is well absorbed through the skin, so when applied to rheumatoid arthritis, the pain stops and inflammation is cured. In addition, it has a strong anti-oxidant effect and UV protection effect, has a skin regeneration effect, and because of its excellent astringent effect, it is known to give a refreshing feeling to the skin and also have an excellent antibacterial effect.

Green tea (Green tea / Thea sinensis Linnaeus) is effective for skin regeneration, atopic dermatitis (dry, etc.), eczema, porridge, and fungal skin diseases. to be. In addition, strong antibacterial action, excellent skin regeneration ability, and has the effect of whitening and clearing the skin.

According to plant taxonomy, Houttuynia cordata is a perennial herb belonging to over three hundreds. The scientific name is called houttunynia cordata, and it is also called medicinal mole in the Korean encyclopedia. Over 46,000 times anti-inflammatory, cures various inflammatory diseases, contains decanoyl acetaldehyde, and fluorides that exceed ginkgo biloba, purify blood, and isoquerchirun and querch torrent, plus Alpha substance rises and promotes the blood transportation of capillaries, so that the metabolism of blood is active and has excellent detoxification effect. To kill has been proven.

Cornus has a tasteful and warm nature, which is used for the symptoms of deterioration of the blood circulation and lack of positive function in the kidney, and is effective in protecting the liver and kidneys. Fruits or leaves of cornus tree may be applied. Although there are some differences in the constituents depending on the site to be applied, the cornus oil may include glycosides such as loganine and saponin, and cornin, malic acid, uric acid, vitamin A, and the like as the constituents. By means of these components, cornus improves metabolism and enhances antidiabetic activity.

Jujube fruit is composed of sugar (fructose, sucrose, glucose, lhamnose), organic acid (single acid, malic acid, wine acid, succinic acid, glycolic acid), protein (chistine, lysine, arginine, etc.), vitamin C , P and inorganic salts (iron, cobalt, phosphorus, iodine). Fruit extract has a diuretic effect and has a blood pressure-lowering effect on hypertensive patients. Jujube has anti-allergic ingredients, so it is good for bronchial asthma, endocrine diseases and psychosis. Jujube with licorice has long been used as an antidote and palliative. It has been used as a neuro stabilizer to treat insomnia, as a health and antidote. Tonic medicine, cough, swelling, when the whole body hurts, irritable purpura is also effective. In the present invention, the fruit is used.

Black soybean has the effect of preventing skin aging due to its antioxidant effect and excellent skin rejuvenation effect, and it has the effect of smoothing and supplying skin nourishment to make it transparent and shiny.

Barley rice has an anti-inflammatory effect, is indispensable for the activation of hair follicle cells, and contains a large amount of the vitamin B group, which is a major component of glucose energy metabolism.

Chamomile is native to Europe, North Africa, and North Asia. Chamomile extracts include alphabisabolol, ascorbic acid, oleic acid, apigenin, quercetin, Aulene, Ahamazulene, Axillarin, Choline, glucose

It contains powder. Among them, Aulene is particularly contained in large amounts, which has a strong antioxidant effect, and is known to exhibit effects such as anti-allergy, skin soothing, anti-inflammatory, and anti-cancer.

Rooibos is the only shrub that grows only in the high altitudes of 450m and over in the Sedberg Mountains of South Africa.It is a conifer that belongs to the legumes and has the nickname of 'Dream of the Skin'. It is effective as an additive in products and various dietary supplements.

Lavender (Lavandula officinalis or Lavandula angustifolia) includes all stems, leaves and flowers of natural, hybrid or varieties of lavender, but preferably means lavender leaves. Preferably, the water extract of lavender can be used as an antiviral composition against coronaviruses.

Gumstone is a substance containing electric energy that radiates large amounts of far infrared rays in the range of 5-20 microns to activate skin cells to facilitate metabolism and to form a thin film (silica layer) of less than 1 micron on inflammatory sites. It acts to prevent bacterial invasion from the outside and neutralizes acidified inflammatory sites in a short time, helping to activate cells and soothing severe itching, preventing inflammation from expanding and promoting blood circulation. .

Cicada is a kind of clay mineral, and its color is silvery white with strong silk gloss. Mineralogically, it belongs to the mica group, and its chemical composition and crystal structure are similar to that of muscovite, and its far-infrared emissivity is about 93%, its anion generation is around 700 / cc, and it emits the safest anions such as low-dose natural radiation, It has the function of adsorbing various harmful substances and is used as a medicine that restores the balance of the broken body and cleans the polluted substances.

Hereinafter, an embodiment of the present invention will be described in detail with reference to the accompanying drawings.

1 is a flow for explaining the steps for producing atopic dermatitis relief functional composition of the present invention, the atopic dermatitis relief functional composition of the present invention by reconcentrating natural herbal extracts and herbal extracts and grain extracts natural natural fermentation method It is prepared by using a nano method.

To this end, first, the collected rock mass is replaced with alkaline ionized water using natural ores (S110).

Rock water is rich in minerals, large mineral power, and strong alkalinity. The water is a living water filled with activated energy, which is a microscopic aggregate of water molecules (clusters) by magnetic fields. Ionization.

As such natural ore, it is preferable to use silica and biotite.

As described above, quartzite promotes the absorption of herbal ingredients into the scalp, and the biotite prevents hair loss and makes hair beautiful.

Alkaline ionized water is electrolytic reduced water. Alkali-reduced water is produced by applying the principles of natural science, where various natural minerals such as magnesium and calcium react with water. Not only ionized minerals in rock water and natural ore are ionized, but also the size Because it is small, its absorption rate is high, and it means water that bacteria can not live without moss even after long standing.

Then, the natural herbal extracts are extracted to be 50% weight (S120).

These natural herbal extracts are extracted with 5% weight of each of the 10 herbal ingredients (Danggui, Peony, wild mulberry leaves, wolfberry, licorice, pine needles, green tea, eochocho, cornus, jujube) to make 50% weight of natural herbal extracts. .

There is no restriction | limiting in particular in the extraction method of such a natural herbal component, It can obtain by the method disclosed so far. An example is briefly described below.

Extraction of Angelica is dried and then finely powdered and placed in a glass container and poured 70% ethanol on it. At this time, the ratio of Angelica powder and ethanol is 1: 1. Thereafter, the glass container is sealed and stored in a cool place free from sunlight for at least 3 years to sufficiently mature the donkey. Thereafter, when a period of three years or more has elapsed, and the component effective for hair growth is sufficiently extracted from the donkey, the contents of the glass can be firstly and secondly filtered with gauze, filter paper, or the like to obtain a donkey extract.

Peony extract is obtained by supercritical extraction of the root of the peony, and the root of Paeonia Lactiflora belonging to the Peony family is extracted using CO2 supercritical extraction solvent and co-solvent butylene glycol, and then butyl Peony extract can be obtained by diluting 15% aqueous solution of butylene glycol (Butylene Glycol).

The extraction of the mulberry leaves was selected and the dried mulberry leaves were washed in the shade and dried in the shade and cut into 0.5-1 cm wide and 2-4 cm long to prevent oxidation of the mulberry leaves and to remove the blue light. Put the mulberry leaves in a broth in order to cool the mulberry leaf liquid, and then cool it and operate it for 15 to 20 minutes. After squeezing for 30 seconds to 1 minute and mixing purified water, and heated water filtration can be extracted mulberry leaf solution of 0.14 ~ 0.17% concentration.

Extraction of wolfberry can be extracted by putting about 50g of wolfberry in 2L of Erlenmeyer flask and adding 800mL of water, boil at least 1 ~ 3 hours for 4 ~ 4 hours at 1 atm, filter it through a 100mesh sieve, and filter it with vacuum.

Licorice extraction is first dried licorice and then finely powdered into a glass container and poured 70% ethanol thereon. At this time, the ratio of licorice powder and ethanol is 1: 1. Thereafter, the glass container is sealed and stored in a cool place without sunlight for at least 3 years to mature licorice. Thereafter, when a period of three years or more has elapsed and the components effective for hair growth from licorice are sufficiently extracted, the contents of the glass container may be filtered first and second with gauze, filter paper, or the like to obtain a licorice extract.

Extraction of pine needles is made by steam extraction method. In general, the raw materials are crushed into small pieces, placed in a closed container and boiled under water to generate high pressure steam. As it cools, the water and the refinery change state, which can be separated and extracted quickly due to the difference in specific gravity.

Extraction of green tea is an extract obtained from leaves, stems or flowers, which can be extracted by the following method. Green tea is soaked in 30% ethanol at 25 ℃ for 4 days, and then filtered using a filter paper to obtain a green tea extract.

Extraction of eochochocho can be obtained by extracting the bioactive material from the eochochocho sample and fermentation or dry extraction of hot water and alcohol extraction.

Cornus and jujube can be extracted by boiling water to boil the active ingredients and dipping them into alcohol to extract the active ingredients. These ingredients are soaked in water for 4 to 5 hours and then boiled on a fire for 3 minutes.

After step S120, three herbal ingredients (chamomile, rooibos, lavender) are tinctured to each 10% by weight to extract (S130).

Tincture is the extraction of active ingredients by dipping alcohol-rich ingredients into the skin, including herbal chamomile, rooibos, and lavender.

This tincture method of extracting the active ingredient in alcohol is a good way to obtain the ingredients of the material without physical and chemical destruction.

When the tincture is completed in step S130 to include the grain components of black beans and barley rice, each 10% by weight (S140).

Specifically, the components extracted from the concentrator are preferably heated to a temperature of 70 ° C. for 6 hours.

In the embodiment of the present invention, the steps S110 to S140 have been described as if they are prepared in order, but the steps S110 to S140 may be extracted regardless of the order.

Then, natural herbal extracts, herbal extracts, and grain extracts extracted in steps S120 to S140, respectively, are concentrated again using alkaline ionized water generated in step S110 to generate a concentrated mixture (S150).

The concentrated mixture produced in step S150 is naturally fermented using yeast and baekbaekpi (S160).

Natural fermentation refers to cultivation using yeast at an average temperature of room temperature so that the components of each other cell are weak.

The white skin used at this time is dried mulberry root bark and has an excellent effect on whitening. It is also used as a functional whitening raw material. It is used to prevent melanin production and makes the skin white, and it is effective in preventing aging and soothing sensitive skin. It works.

After the fermentation broth fermented in step S160 to obtain a functional composition for atopic dermatitis mitigation by nanotechnology (S170).

Such compositions have a formulation as is liquid.

Nano method is a method of extracting the active ingredient and functional bioactive material in the state of ultra-fine particles without thermal destruction, it is preferable to use the low temperature nano extraction method.

In the nano process, the absorption rate of non-nano-processed products such as minerals is only 5% on average, but when processed into nano-particles, the absorption rate is almost 100%. There is an effect of showing the absorption rate.

The functional composition for atopic dermatitis alleviation generated as described above can be absorbed to the dermal layer instantaneously by using nanotechnology to alleviate atopic dermatitis applied to the skin, thereby increasing the moisturizing power and blocking harmful irritants. There is no irritation to the skin and it has the effect of releasing antioxidant, anti-inflammatory and skin toxin.

While the invention has been described in detail with respect to the embodiments described, it will be apparent to those skilled in the art that various modifications and variations are possible within the spirit of the invention, and such modifications and variations belong to the appended claims.

1 is a flow chart for explaining the steps of producing a functional dermatitis functional composition for atopic dermatitis of the present invention.

Claims (11)

Functional composition for atopic dermatitis alleviation, characterized in that the composition of the natural herbal extract 50%, herb extract 30%, and grain extract 20% by concentration in alkaline water and fermented naturally by a nano method. The method of claim 1, The alkaline water is Functional composition for alleviating atopic dermatitis, which is produced by replacing rock water with alkaline ionized water using silicon and biotite. 3. The method of claim 2, The natural herbal extracts Functional composition for atopic dermatitis alleviation, characterized in that extracted with 5% by weight of each of the 10 herbal ingredients (Dangui, peony, wild mulberry leaves, goji berry, licorice, pine needles, green tea, eochocho, cornus, jujube). The method of claim 3, The herbal extract is Functional composition for atopic dermatitis alleviation, characterized in that extracted by tincture in chamomile 10% by weight, rooibos 10% by weight, and lavender 10% by weight. The method of claim 4, wherein The grain extract is Functional composition for atopic dermatitis alleviation, characterized in that the extract in black bean 10% weight and barley rice 10% weight. The method of claim 5, The natural fermentation Functional composition for alleviating atopic dermatitis, characterized in that the mixture concentrated with alkaline water is fermented using yeast and baekryepi. a) replacing the rock water with alkaline ionized water using natural ore; b) extracting the natural herbal components; c) tinting and extracting the herbal components; d) decoction of the grain; e) concentrating the extract of steps b) to d) again with alkaline ionized water generated in step a); and f) a step of naturally fermenting the concentrated mixture of step e) using yeast and lettuce; Atopic dermatitis relief functional composition production method consisting of. The method of claim 7, wherein Step a) Method for producing a hair growth promoting composition, characterized in that to produce alkaline water by replacing the rock water with silicon and biotite. The method of claim 8, Step b) is The natural herbal ingredients A method for producing a functional dermatitis for atopic dermatitis, characterized by extracting with 5% by weight of each of the 10 herbal ingredients (Dangui, peony, wild mulberry leaves, wolfberry, licorice, pine needles, green tea, eochocho, cornus, jujube). The method of claim 9, Step c) Method for producing atopic dermatitis relief functional composition, characterized in that extracted by tincture in 10% by weight of chamomile, 10% by weight of rooibos, and 10% by weight of lavender. The method of claim 10, Step d) Method for producing atopic dermatitis relief functional composition, characterized in that the extract in black bean 10% weight and barley rice 10% weight.

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