CN102755444A - Traditional Chinese medicine composition for treating hyperlipidemia and preparation method thereof - Google Patents

Traditional Chinese medicine composition for treating hyperlipidemia and preparation method thereof Download PDF

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CN102755444A
CN102755444A CN201210282388XA CN201210282388A CN102755444A CN 102755444 A CN102755444 A CN 102755444A CN 201210282388X A CN201210282388X A CN 201210282388XA CN 201210282388 A CN201210282388 A CN 201210282388A CN 102755444 A CN102755444 A CN 102755444A
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chinese medicine
parts
medicine composition
hyperlipidemia
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赵正竹
赵燕梅
张寒
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SUZHOU SHENLIANG BIOLOGICAL TECHNOLOGY Co Ltd
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SUZHOU SHENLIANG BIOLOGICAL TECHNOLOGY Co Ltd
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Abstract

The invention relates to a traditional Chinese medicine composition for treating hyperlipidemia and a preparation method thereof. The traditional Chinese medicine composition is prepared by natural plant raw materials, by weight, of 20-50 parts of momordica charantia, 10-30 parts of the fruit of Chinese wolfberry, 10-30 parts of the root of kudzu vine, 5-25 parts of honeysuckle and 4-20 parts of pumpkin flower. The preparation method of the traditional Chinese medicine composition comprises a water extraction method, a direct grinding method or a method combined the water extraction method with the direct grinding method. A formula of the traditional Chinese medicine composition combines Chinese and Western medicine theories, is compounded to conduct compatibility of medicines, and can restrain cholesterol absorption, adjust metabolism of lipidemia and promote cholesterol excretion to achieve good treating effects. In addition, all raw materials of the traditional Chinese medicine composition are the natural plant raw materials, are wide in source, simple in formula component, and simple and convenient to prepare.

Description

A kind of Chinese medicine composition that is used to treat hyperlipidemia and preparation method thereof
Technical field
The invention belongs to technical field of Chinese medicines, particularly a kind of Chinese medicine composition that can be used for treating hyperlipidemia and preparation method thereof.
Background technology
Hyperlipidemia is a kind of common and multiple metabolic disease, is the important risk factor that causes cardiovascular and cerebrovascular disease.Hyperlipidemia is common in middle-aged and elderly people, but along with the raising of national life level, the change of dietary structure, the hyperlipidemia prevalence of adolescence is also increasing year by year." Chinese residents nutrition in 2004 and Health Situation " investigation report points out that China adult dyslipidemia prevalence is 18.6%, and national dyslipidemia is suffered from number 1.6 hundred million at present, and the middle-aged and elderly people prevalence is close, and differentials between town and country are little.Develop safe and efficient antihyperlipidemic product and become current pressing for.
At present, hypolipidemic clinically is to be main with chemical medicine (being mainly the Statins Western medicine prepn at present), though instant effect, side effect is big, and general patient is difficult to accept; And the common drug effect of chemical medicine is difficult to need take for a long time lastingly, and toxic and side effects is more remarkable, and severe patient can produce Cardiovascular Toxicity and liver toxicity, and therefore, exploitation auxiliary antilipemic product has important practical significance from Chinese medicine or in the food.
Think on the Chinese medicine that hyperlipidemia is a deficiency in origin and excess in superficiality, belong to blood stasis, the turbid category of expectorant, its disease is sent out in taste at blood, and root is in kidney.Clinical syndrome differentiation belongs to caused by liver and kidney deficiency, turbid, the qi depression to blood stasis of insufficiency of the spleen expectorant more, adopts the medicine of liver and kidney tonifying, invigorating the spleen and benefiting QI, nourishing YIN and benefiting blood, blood circulation promoting and blood stasis dispelling, clearing away heat and promoting digestion during treatment mostly.See that from the modern medicine viewpoint effect for reducing fat of Chinese medicine is mainly drained and embodied from inhibition absorption of cholesterol, blood lipid regulation metabolism, promotion cholesterol.
Make a general survey of present research situation to hyperlipidemia, the research of Chinese medicine single medicine and compound preparation is many, but general effect is not satisfactory.Perhaps, though some Chinese medicine preparation has been obtained reasonable therapeutic effect, prescription is complicated, on the one hand, complicated process of preparation, cost is higher; On the other hand, the composition of prescription fails to confirm that very clearly safety can't effectively be guaranteed.
Summary of the invention
Technical problem to be solved by this invention overcomes the deficiency of prior art, and a kind of Chinese medicine composition that is used to treat hyperlipidemia is provided, and this Chinese medicine composition is evident in efficacy, and its composition is simple, method for preparing is easy.
The present invention also will provide a kind of method for preparing that is used to treat the Chinese medicine composition of hyperlipidemia simultaneously, and this method is simple, and cost is low, and the traditional Chinese medicine composition for treating effect that obtains is remarkable.
For solving above technical problem, a kind of technical scheme that the present invention takes is following:
A kind of Chinese medicine composition that is used to treat hyperlipidemia, its natural plant raw material following weight portion is prepared from: 20~50 parts of bright and beautiful Fructus Litchi, 10~30 parts of Fructus Lycii, 10~30 parts of Radix Puerariaes, 5~25 parts of Flos Loniceraes, 4~20 parts of Flos Cucurbitaes.
Preferably, said Chinese medicine composition is prepared from the natural plant raw material of following weight portion: 30~40 parts of bright and beautiful Fructus Litchi, 15~25 parts of Fructus Lycii, 15~25 parts of Radix Puerariaes, 10~20 parts of Flos Loniceraes, 8~18 parts of Flos Cucurbitaes.
More preferably, said Chinese medicine composition is prepared from the natural plant raw material of following weight portion: 34~36 parts of bright and beautiful Fructus Litchi, 18~22 parts of Fructus Lycii, 18~22 parts of Radix Puerariaes, 12~16 parts of Flos Loniceraes, 9~11 parts of Flos Cucurbitaes.
According to the present invention, all raw materials all are known, and the research of comparative maturity is arranged, and are specific as follows: bright and beautiful Fructus Litchi, be the Fructus Momordicae charantiae of southern Jiangsu real estate, and bitter in the mouth, cold in nature, return spleen channel.Pharmacological evaluation prompting, bright and beautiful Fructus Litchi water extraction fluid power reduce TC, TG, LDL index in the hyperlipidemia mice serum, the HDL that slightly raises, and the fat drop quantity of minimizing hyperlipidemia mouse liver cell is improved hepatic pathology and is changed, and has effect for reducing blood fat preferably;
Radix Puerariae, sweet in the mouth, suffering, property is flat, returns the taste warp, and contained isoflavonoid has effect for reducing blood fat in the Radix Puerariae; Be that the Chinese patent medicine painstaking effort processed of primary raw material are peaceful, the XINANNING sheet all has lipid-lowering effect preferably with the Radix Puerariae extract; The kudzu root oral liquid apoA-I in the ethanol property hyperlipidemia rats blood that can raise reduces TC, TG.
Fructus Lycii, sweet in the mouth, property is flat, returns liver, kidney channel.Tool nourishing the liver nourishing kidney effect is used for caused by liver and kidney deficiency.Fructus Lycii has blood fat reducing and protects the liver, lipotropy, not only triglyceride reducing but also cholesterol reducing.With the Fructus Lycii is the fat regulating tablet that lengthens one's life of primary raw material, and the fat recovery capsule can significantly be regulated the blood lipid level of hyperlipidemia rats.Fructus Lycii liquid then has the effect of serum total cholesterol (TC) in the obvious reduction blood, triglyceride (TG), low-density lipoprotein cholesterol (LDL-C) and the effect that reduces TC, TG in the liver;
Flos Lonicerae, sweet in the mouth, cold in nature.Return the stomach warp.The tool heat-clearing toxin-expelling functions.Flos Lonicerae is the good medicine of heat-clearing and toxic substances removing, clearing away heat with drugs sweet in flavor and cold in nature and not injuring one's stomach, also kind removing summer-heat blood poison.Zoopery shows that Flos Lonicerae can reduce the enteral cholesterol absorption, reduces content of cholesterol in the blood plasma, triglyceride reducing.Flos Lonicerae extract can make hyperlipemia in mice, rat blood serum and hepatic tissue TG level obviously reduce, and certain effect for reducing blood fat is arranged;
Flos Cucurbitae, sweet in the mouth, cool in nature, tool clearing away damp-heat, the malicious effect of subsiding a swelling.
The another technical scheme that the present invention takes is: the method for preparing of the Chinese medicine composition of hyperlipidemia is treated in a kind of above-mentioned being used to; As follows: take by weighing whole said raw materials in proportion; Water decocts 2 ~ 3 times, collecting decoction, concentrate concentrated solution; The spray-dried method of concentrated solution obtains powder or graininess extract, is the Chinese medicine composition that is used to treat hyperlipidemia.
Preferably, water decocts 2 times.
Perhaps; The Chinese medicine composition that is used to treat hyperlipidemia of the present invention also can be through following scheme implementation: the method for preparing of the Chinese medicine composition of hyperlipidemia is treated in a kind of above-mentioned being used to; As follows: take by weighing whole raw materials in proportion; Pulverize, cross 50 ~ 80 mesh sieves, be the Chinese medicine composition that is used to treat hyperlipidemia.
Preferably; Can also prepare the Chinese medicine composition that hyperlipidemia is treated in above-mentioned being used to through following method, that is: take by weighing whole raw materials in proportion, and whole raw materials are divided into two parts that weight ratio is 0.8 ~ 1.2:1; A part of water wherein decocts 2 ~ 3 times; Collecting decoction, concentrate concentrated solution, the spray-dried method of concentrated solution obtains powder or graininess extract; Remaining another part is directly pulverized, and behind 50 ~ 80 mesh sieves, mixes evenly with powder or graininess extract excessively, promptly gets the Chinese medicine composition that is used to treat hyperlipidemia.
Preferably, the weight ratio of above-mentioned two parts is about 1:1.
The present invention also is particularly related to a kind of Chinese medicine preparation that is used to treat hyperlipidemia, and its effective ingredient comprises above-mentioned Chinese medicine composition at least.
According to the present invention, the dosage form that said Chinese medicine preparation can prepare and take for various suitable being convenient to.For example, Chinese medicine preparation can be capsule, tablet or the granule that is prepared from by conventional technology of preparing.
Owing to take above technical scheme, the present invention compared with prior art has following advantage:
Bright and beautiful Fructus Litchi in the Chinese medicine composition of the present invention, Radix Puerariae, Fructus Lycii, the equal tool effect for reducing blood fat of Flos Lonicerae, bright and beautiful Fructus Litchi, Radix Puerariae spleen invigorating, Fructus Lycii nourishing the liver and kidney; Flos Lonicerae, Flos Cucurbitae heat clearing away; All flavors share, function of spleen and stomach regulating and the kidney invigorating, then blood-fat-decreasing effectively.The present invention fills a prescription and merges the Chinese and western medical theory, and compound compatibility can suppress absorption of cholesterol, blood lipid regulation metabolism, promote cholesterol to drain, thereby reach extraordinary therapeutic effect.In addition, whole raw materials of the present invention are natural plant raw material, wide material sources, and recipe ingredient is simple, prepares easy.
The specific embodiment
Below in conjunction with concrete embodiment the present invention is done further detailed explanation, but the invention is not restricted to following examples.
Embodiment 1
A kind of Chinese medicine composition that is used to treat hyperlipidemia, its composition of raw materials is following: 35 parts of bright and beautiful Fructus Litchi, 20 parts of Fructus Lycii, 20 parts of Radix Puerariaes, 15 parts of Flos Loniceraes, 10 parts of Flos Cucurbitaes.
The preparation process of Chinese medicine composition is following: take by weighing whole raw materials in proportion; And whole raw materials are divided into equiponderant two parts, a part of water wherein decocts collecting decoction 2 times; Concentrate concentrated solution, the spray-dried method of concentrated solution obtains Powdered extract; Another part is directly pulverized, and behind 60 mesh sieves, with the powder extracts mix homogeneously, promptly gets the Chinese medicine composition that is used to treat hyperlipidemia excessively.
Embodiment 2
A kind of Chinese medicine composition that is used to treat hyperlipidemia, its composition of raw materials are with embodiment 1, but method for preparing is different.Specifically, Chinese medicine composition adopts conventional water extraction method preparation in this example, and is specific as follows: as to take by weighing whole raw materials in proportion; Water decocts 2 times, collecting decoction, concentrate concentrated solution; The spray-dried method of concentrated solution obtains Powdered extract, is this routine said Chinese medicine composition.
Embodiment 3
A kind of Chinese medicine composition that is used to treat hyperlipidemia, its composition of raw materials is following: 30 parts of bright and beautiful Fructus Litchi, 15 parts of Fructus Lycii, 25 parts of Radix Puerariaes, 15 parts of Flos Loniceraes, 15 parts of Flos Cucurbitaes.This routine Chinese medicine composition is according to preparing with embodiment 1 identical method.
Embodiment 4
A kind of Chinese medicine composition that is used to treat hyperlipidemia, its composition of raw materials is following: 40 parts of bright and beautiful Fructus Litchi, 15 parts of Fructus Lycii, 25 parts of Radix Puerariaes, 10 parts of Flos Loniceraes, 10 parts of Flos Cucurbitaes.This routine Chinese medicine composition is according to preparing with embodiment 1 identical method.
Embodiment 5
A kind of Chinese medicine composition that is used to treat hyperlipidemia, its composition of raw materials is following: 25 parts of bright and beautiful Fructus Litchi, 12 parts of Fructus Lycii, 30 parts of Radix Puerariaes, 20 parts of Flos Loniceraes, 13 parts of Flos Cucurbitaes.This routine Chinese medicine composition is according to preparing with embodiment 1 identical method.
Embodiment 6
A kind of Chinese medicine composition that is used to treat hyperlipidemia, its raw material are with embodiment 5, and method for preparing is with embodiment 2.
Comparative Examples 1
This Comparative Examples provides a kind of Chinese medicine composition that is used to treat hyperlipidemia, and its composition of raw materials is following: 40 parts of bright and beautiful Fructus Litchi, 25 parts of Fructus Lycii, 20 parts of Radix Puerariaes, 15 parts of Flos Loniceraes.This routine Chinese medicine composition is according to preparing with embodiment 1 identical method.
Comparative Examples 2
This Comparative Examples provides a kind of Chinese medicine composition that is used to treat hyperlipidemia, and its composition of raw materials is following: 35 parts of bright and beautiful Fructus Litchi, 25 parts of Fructus Lycii, 25 parts of Radix Puerariaes, 15 parts of Flos Cucurbitaes.
Comparative Examples 3
This Comparative Examples provides a kind of Chinese medicine composition that is used to treat hyperlipidemia, and its composition of raw materials is following: 40 parts of bright and beautiful Fructus Litchi, 30 parts of Fructus Lycii, 30 parts of Radix Puerariaes.
Chinese medicine composition of the present invention is used to treat the effect of hyperlipidemia
Chinese medicine composition provided by the present invention be the inventor through long-term practice, research and sum up gained.The inventor is surprised to find that in long-term practice the Chinese medicine composition that these five kinds of raw material reasonable compatibilities of bright and beautiful Fructus Litchi, Fructus Lycii, Radix Puerariae, Flos Lonicerae and Flos Cucurbitae are prepared has showed for the outstanding therapeutic effect of treatment hyperlipidemia symptom.Though each raw material of formation compositions all has research and confirms that the effect that reduces fat is arranged, the curing protrusion effect that they are obtained according to the special ratios combination then is that inventor's accident in long-term practice is found and summary obtains.
Application has capsule or granule treatment hyperlipidemia 240 examples that the Chinese medicine composition of embodiment 1 said prescription is processed; Have capsule or the granule that the Chinese medicine composition of embodiment 2 ~ 6 said prescriptions processes and treat hyperlipidemia 12 examples respectively; It is about 96%, 98% and 72% that the total effective rate that reduces TC, TG and rising HDL-C is respectively, without any side effects.Use capsule or granule treatment hyperlipidemia 20 examples that the Chinese medicine composition of Comparative Examples 1 ~ 3 is processed respectively, it is about 65%, 60% and 35% that the total effective rate that reduces TC, TG and rising HDL-C is respectively, without any side effects.
Most of patients is taken and is got final product a course of treatment.Find for same patient, hyperlipidemia symptom person is arranged obviously particularly in the practice, the capsule of taking the Chinese medicine composition that comprises embodiment 1 is better than the capsular therapeutic effect of taking the Chinese medicine composition that comprises embodiment 2.
With capsule (to call brocade flower complex capsule in the following text) is example, in the practice, adopts No. 0 or No. 1 capsule, and in the capsule, the content of Chinese medicine composition is 0.35~0.40g/ grain.For general hyperlipidemia symptom person, oral, every day secondary, each 2; Or once a day, each four, taking one month is a course of treatment; For obvious hyperlipidemia symptom person is arranged, recommending consumption is every day three times, and each 3, taking one month is a course of treatment, takes no ill effect for a long time.
Typical case is following:
1. Lee, man, 56 years old.Hypertension history, hyperlipidemia history are previously arranged.Patient nearly February is uncomfortable in chest obviously, and time makes up one's mind and throbs with fear.Heavy when light when uncomfortable in chest, in time, makes up one's mind and throbs with fear, receive food still can, but abdominal distention after meal, fullness in the hypochondrium is vexed, stool every day 2~3 times, whole body ache, edema of pair of lower extremities, it is not good enough to sleep.Blood fat: T-CHOL (TC) 6.32mmol/L, triglyceride (TG) 2.90mmol/L.Control with brocade flower complex capsule, recommending consumption is every day three times, each 3, takes one month.Obeyed my private prosecution of back: whole body muscles and bones muscle stretches happy, uncomfortable in chest, cardiopalmus, abdominal distention, fullness in the hypochondrium is vexed does not have, receives and eat, sleeps the every day 1 time of defecating, and two lower limb have not had edema.The examination blood fat, T-CHOL (TC) 4.92mmol/L, triglyceride (TG) 1.70mmol/L.Phone is followed up a case by regular visits to after 2 months, no significant discomfort, and blood fat is normal.
2. Ma, the man, 45 years old, hyperlipidemia for many years, oral fat-reducing medicament treatment, blood fat control is not good, after chest occurs and feel oppressed and breathe hard dizziness, weak symptom.
Inspection on an empty stomach: TC:6.12mmol/L, TG:2.55mmol/L.
The electrocardiogram prompting: atrial fibrillation, S-T section V5-6 moves down 0.2mv, Color Sonography " left chamber cardiac dilatation, left chamber diastolic function is bad ".
Cardiac inspection: presystole (PEP) prolongs, left ventricular ejection time (LVET), and PEP/LVET ratio increases.
Have a medical check-up: blood pressure 150/90mmHg, jugular vein is full, the apex beat disperse, hear sounds is low blunt, heart rate 92 times/minute, rule is neat, and the apical region of heart is heard and blowing systolic murmur, and two bases of lung are heard and a small amount of moist rale, 1cm under the liver rib, edema of lower limbs.
Diagnosis: cardiomyopathy, hyperlipidemia.
Give brocade flower complex capsule according to patient's the state of an illness and take, after taking 10 days, effectively reduced myocardial oxygen consumption, improved myocardial ischemia, left ventricular function is restored.Continue to take brocade flower complex capsule, suggestion is simultaneously suitably had a rest diet: eat and be easy to the balanced diet that digests a bit, pay attention to being rich in lean meat, fish, fowl, egg, milk and fresh vegetables, the fruit of high quality protein, vitamin on time.Check blood fat after one month, T-CHOL (TC) 5.0mmol/L, triglyceride (TG) 1.5mmol/L.
3. Wang, the man, 65 years old, dizzy, headache, nervous, irritated appearred in 5 years history of hypertension in the recent period.Through looking into, blood fat T-CHOL (TC) 15.8mmol/L, triglyceride (TG) 8.7mmol/L, blood pressure 198/110mmHg, clinical diagnosis is a hypertension, hyperlipidemia.
Advise it and take brocade flower complex capsule, every day three times, each 3, took one month.After the course of treatment, it is clearheaded that the patient feels, the blood fat T-CHOL drops to 8.03mmol/L, and triglyceride drops to 5.40mmol/L.Recommend the patient to take second course of treatment, every day, secondary, was adjusted mentality, in good time appropriate exercise by each 3, and advise patient's light diet.Patient's lipid cholesterol is 6.02mmol/L after second course of treatment, and triglyceride is 2.84mmol/L, blood pressure 150/88mmHg, and all malaise symptoms disappear.
The king so-and-so, woman, 57 years old.Private prosecution: dizziness, headache, dim eyesight, hypomnesis, the complete obiteration of left foot half sole feeling of numbness.Morbidity is severe pain at first, and the later stage pain disappears, and numb imperception replaces pain.
Lipid examination: T-CHOL (TC) 7.12mmol/L, low density lipoprotein, LDL (LDL--C) 4.84mmol/L, high density lipoprotein (HDL--C) 0.83mmol/L, triglyceride (TG) 3.19mmol/L.
Diagnosis: left lower extremity atherosclerotic occlusive disease, hyperlipidemia model case.
Take brocade flower complex capsule treatment one month, and advise its strictness to keep on a diet, adjust mentality.Stiff withered skin has point elasticity, obvious gloss, and pain disappears and regains consciousness, after three times treatment, the complete obiteration of the uncomfortable sensation of patient, leg muscle elasticity strengthens gradually, and muscular tissue thickens, and the whole blood flow of left lower extremity fills.T-CHOL (TC) 4.02mmol/L, low density lipoprotein, LDL (LDL--C) 2.09mmol/L, high density lipoprotein (HDL--C) 1.12mmol/L, triglyceride (TG) 1.79mmol/L.Orthobiosis and work at present.
More after: follow up a case by regular visits to half a year so far, conditions of patients is stable, recurrence.
5, name: Zhao, woman, age: 58 years old
Private prosecution: before three months, lightheaded phenomenon appears in health suddenly, and the patient thinks oneself as and overworks, and just is in and takes a quick nap.After suddenly health numb limbs and tense tendons appears, dizziness, weak, be difficult to control.Be diagnosed as the concurrent cerebral infarction of hyperlipidemia, apoplexy is with the symptom of hemiplegia.Be able to control but activity can not be can't take care of oneself freely in 4 months state of an illness of hospitalize.Take brocade flower composite powder capsule through friend's introduction.The patient has been carried out comprehensive inspection, inspection 1 grade of muscular strength (limbs are stiff), blood pressure is 180/140mmhg.Blood fat T-CHOL 10.9mmol/L, triglyceride fat 5.67.
The Ipsilateral upper limb is edema slightly, and that touches is cool slightly, pale tongue with indented margin, stringy and rolling pulse.
Treating for the first time aftersensation trouble limb has the hypodynia sense, dizziness headache, and weak sx, treatment back future trouble limb edema obviously disappears for the second time, and blood pressure, blood fat obviously descend.Blood fat T-CHOL 6.9mmol/L, triglyceride fat 3.15mmol/L.After the treatment, malaise symptoms disappears basically for the third time, blood pressure 130/80mmHg, and blood fat T-CHOL 6.1mmol/L, the existing 1.8mmol/L of three ester glycerol suffers from the limb muscular strength more than 4 grades, and right hand activity is freely.Conditions of patients is taken regular exercise after taking a turn for the better.The state of an illness is basicly stable, and existing patient body, the mental status are good, and vital sign is steady, and freedom of movement does not have special discomfort, and the no abnormality seen of having a medical check-up has recovered normal person's life.
More than the present invention has been done detailed description; Its purpose is to let the personage that is familiar with this art can understand content of the present invention and implements; Can not limit protection scope of the present invention with this; All equivalences of doing according to spirit of the present invention change or modify, and all should be encompassed in protection scope of the present invention.

Claims (10)

1. Chinese medicine composition that is used to treat hyperlipidemia, it is characterized in that: said Chinese medicine composition is prepared from the natural plant raw material of following weight portion: 20~50 parts of bright and beautiful Fructus Litchi, 10~30 parts of Fructus Lycii, 10~30 parts of Radix Puerariaes, 5~25 parts of Flos Loniceraes, 4~20 parts of Flos Cucurbitaes.
2. the Chinese medicine composition that is used to treat hyperlipidemia according to claim 1 is characterized in that: said Chinese medicine composition is prepared from the natural plant raw material of following weight portion: 30~40 parts of bright and beautiful Fructus Litchi, 15~25 parts of Fructus Lycii, 15~25 parts of Radix Puerariaes, 10~20 parts of Flos Loniceraes, 8~18 parts of Flos Cucurbitaes.
3. the Chinese medicine composition that is used to treat hyperlipidemia according to claim 2 is characterized in that: said Chinese medicine composition is prepared from the natural plant raw material of following weight portion: 34~36 parts of bright and beautiful Fructus Litchi, 18~22 parts of Fructus Lycii, 18~22 parts of Radix Puerariaes, 12~16 parts of Flos Loniceraes, 9~11 parts of Flos Cucurbitaes.
4. one kind like the described method for preparing that is used to treat the Chinese medicine composition of hyperlipidemia of each claim in the claim 1 ~ 3; It is characterized in that: take by weighing whole said raw materials in proportion; Water decocts 2 ~ 3 times, collecting decoction, concentrate concentrated solution; The spray-dried method of concentrated solution obtains powder or graininess extract, is the said Chinese medicine composition that is used to treat hyperlipidemia.
5. method for preparing according to claim 4 is characterized in that: water decocts 2 times.
6. one kind like the described method for preparing that is used to treat the Chinese medicine composition of hyperlipidemia of each claim in the claim 1 ~ 3; It is characterized in that: take by weighing whole said raw materials in proportion; Pulverize, cross 50 ~ 80 mesh sieves, be the said Chinese medicine composition that is used to treat hyperlipidemia.
7. one kind like the described method for preparing that is used to treat the Chinese medicine composition of hyperlipidemia of each claim in the claim 1 ~ 3; It is characterized in that: take by weighing whole said raw materials in proportion; And whole said raw materials are divided into two parts that weight ratio is 0.8 ~ 1.2:1, a part of water wherein decocts collecting decoction 2 ~ 3 times; Concentrate concentrated solution, the spray-dried method of concentrated solution obtains powder or graininess extract; Remaining another part is directly pulverized, and behind 50 ~ 80 mesh sieves, mixes evenly with said powder or graininess extract excessively, promptly gets the said Chinese medicine composition that is used to treat hyperlipidemia.
8. Chinese medicine preparation that is used to treat hyperlipidemia is characterized in that: the effective ingredient of said Chinese medicine preparation comprises in the claim 1 ~ 3 each right at least and wants described Chinese medicine composition.
9. the Chinese medicine preparation that is used to treat hyperlipidemia according to claim 8 is characterized in that: capsule, tablet or the granule of said Chinese medicine preparation for being prepared from by conventional technology of preparing.
10. claim 8 or 9 described Chinese medicine preparation are used to treat or the purposes of auxiliary treatment hyperlipidemia.
CN201210282388XA 2012-08-06 2012-08-06 Traditional Chinese medicine composition for treating hyperlipidemia and preparation method thereof Pending CN102755444A (en)

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Application publication date: 20121031