CN103919910B - A kind of medicine for the treatment of coronary heart disease - Google Patents
A kind of medicine for the treatment of coronary heart disease Download PDFInfo
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Abstract
The invention discloses a kind of medicine for the treatment of coronary heart disease, formulated according to a certain percentage by Radix Salviae Miltiorrhizae, Radix Panacis Quinquefolii, Rhizoma Corydalis (processed with vinegar), Radix Rehmanniae Preparata, Fructus Corni, Fructus Crataegi, gun additioner, Fructus Schisandrae Chinensis, Ramulus Cinnamomi, Radix Angelicae Sinensis, the Radix Astragali, Radix Glycyrrhizae, Rhizoma Chuanxiong, Flos Lonicerae.The invention also discloses a kind of method preparing said medicine.Medicine of the present invention is used for the treatment of coronary heart disease, not only can blood circulation promoting and blood stasis dispelling, and coronary circulation-promoting pain-relieving, can also nourish heart in nourishing kidney.Through the display of clinical trial for many years, be used for the treatment of coronary heart disease, the diseases such as what Coronary Heart Disease Patients thrombosis can be made to cause feels oppressed, the nervous cardiopalmus that ischemia causes are eliminated.Medicine of the present invention have short treating period, instant effect, cure rate high, have no side effect, safe and reliable feature.
Description
Technical field
The invention belongs to technical field of Chinese medicines, be specifically related to a kind of Chinese medicine for the treatment of coronary heart disease.
Background technology
Coronary heart disease and coronary atherosclerotic heart disease (coronary artery heart disease, CHD), the traditional Chinese medical science claims " thoracic obstruction ", a kind of modal heart disease, refer to because coronary atherosclerosis makes coronary stricture, blood supply insufficiency and the myocardial dysfunction caused and (or) organic disease, therefore also known as ischemic cardiomyopathy (IHD).Coronary heart disease is the result of multiple coronary artery pathological changes.But coronary atherosclerosis accounts for the overwhelming majority (95%-99%) of coronary heart disease.Therefore, traditionally coronary heart disease is considered as coronary atherosclerotic heart disease (coronary atherosclerotic heartdisease).Be mainly in middle-aged and elderly people, suffer from the women of this disease more than male in China.
Coronary heart disease cardinal symptom is the squeezing sense of sudden shirtfront or pain, or there is paroxysmal pain at left breastbone rear portion, also can feed through to the positions such as most of pareordia.Pale complexion during outbreak, expression anxiety or agitation, palpitation and uneasiness, have palpitation, breathe hard, si dol urg can accompany and see cold sweat, often can cause sudden death.The traditional Chinese medical science is thought, the pathogenesis of coronary heart disease is that heart arteries and veins is obstructed, how because blood stasis, expectorant are turbid, the stagnation of QI and causing, be again the result of long-term visceral dysfunction, often with heavy meal, catch cold, tired, direct stimulation is pathogenesis etiology.
Because Incidence of CHD is high, mortality rate is high, and the healthy of the mankind in serious harm, is referred to as " first killers of the mankind ".The medicament categories for the treatment of coronary heart disease is a lot, and great majority western medicine, cures the symptoms, not the disease.Its therapy approach, mainly with the medicine adopting coronary dilating and decreased heart rate, improves myocardial oxygen delivery and reduces myocardial oxygen consumption, thus alleviating state of an illness symptom.Facts have proved, though this kind of medicine can alleviate disease to a certain extent, there is impairment of YIN all the time, consumption gas, difficult Da Zhiben is sorry.Normally better during medication, just get back to the original state of an illness again once drug withdrawal, if inappropriate medication, also may fail to respond to any medical treatment and even increase the weight of disease.Mainly with blood circulation promoting and blood stasis dispelling in the new Chinese medicine of the treatment angina pectoris gone on the market in recent years, regulating QI to relieve pain therapy is main, as DIAOXINXUE KANG, Salvia Miltiorrhiza Oral Liquid, FUFANG DANSHEN JIAONANG, XINTONGKOU PIAN, BUXINQI KOUFUYE, taste the heart-yin oral liquid, Yiqi oral liquid medicine preparation etc., although certain effect can be played, but clinical research shows: the heart is suffered from a deficiency of the kidney the weak etiology and pathogenesis common for year high people, and singly executing promoting blood circulation by removing blood stasis can't effect a radical cure.
Summary of the invention
The object of the invention is by tcm therapy, adopts traditional Chinese medical science wholistic therapy idea, plays the advantage that the traditional Chinese medical science is effected a permanent cure, and by adjusting the imbalance between YIN and YANG of whole body, accomplish blood circulation promoting and blood stasis dispelling, regulating QI to relieve pain, nourishing kidney is nourished heart, thus fundamentally eliminates coronary heart disease.
Technical solution of the present invention is as follows, a kind of medicine for the treatment of coronary heart disease, and each crude drug component is by weight ratio: Radix Salviae Miltiorrhizae 10-30 part, Radix Panacis Quinquefolii 10-20 part, Rhizoma Corydalis (processed with vinegar) 10-20 part, Radix Rehmanniae Preparata 20-50 part, Fructus Corni 10-20 part, Fructus Crataegi 10-20 part, gun additioner 5-10 part, Fructus Schisandrae Chinensis 2-5 part, Ramulus Cinnamomi 5-10 part, Radix Angelicae Sinensis 10-25 part, Radix Astragali 15-30 part, Radix Glycyrrhizae 5-10 part, Rhizoma Chuanxiong 5-15 part, Flos Lonicerae 10-20 part.
Medicine of the present invention is any one in oral solutions, powder, tablet, capsule.During preparation, first by Rhizoma Corydalis processed with vinegar, preparation technology is: first corydalis tuber medicinal material is processed into granule, crosses 5 mesh sieves; Then add rice vinegar according to Corydalis Granule and rice vinegar weight ratio 5:1 to stir, place moistening; After rice vinegar is absorbed by medical material, put in pot and fry to micro-dry with slow fire, taking-up cools, and to obtain final product; Extract oral liquor, powder, tablet, capsule is prepared into further according to conventional Chinese medicine preparation method.
The preparation method of described oral solutions is: prepare crude drug according to said ratio, total raw material medicine is soaked at least 0.5 hour according to 1:2 ~ 4, then adds suitable quantity of water and decoct 0.5 ~ 2 hour, considers and removes sterile preservation or sterile filling after medicinal residues.
The preparation method of described powder is: prepare crude drug according to said ratio, be mixed in proportion after each former medicine is ground to form fine powder, and crosses 100 ~ 200 mesh sieves, is powder; Or powder compaction is become tablet, or powder is incapsulated make capsule.
The preparation method of described tablet, capsule is: prepare crude drug according to said ratio, total raw material medicine is soaked at least 0.5 hour according to 1:2 ~ 10, add suitable quantity of water again to decoct 0.5 ~ 2 hour, elimination medicinal residues, under the condition of negative pressure, low temperature, the Chinese medicine leaching liquid of clarification being concentrated into Bomi degree is more than 80%, make dry powder (temperature≤100 DEG C of spout) by powder spraying apparatus, then make tablet or capsule after absorb fillers in dry powder.
Medicament composing prescription of the present invention is unique, formula is rigorous, select YAOJING to refine, and each component drug synergism, complements each other, and has many effects such as nourishing kidney yin, warm Yuanyang, benefiting QI and nourishing blood, blood circulation promoting and blood stasis dispelling, removing summer-heat blood poison, regulating QI to relieve pain.Clinical trial proves, Drug therapy coronary heart disease curative effect of the present invention is rather good.
The pharmacological effect of medicine of the present invention each component raw material medicine is as follows:
Radix Salviae Miltiorrhizae, bitter, be slightly cold.GUIXIN, Liver Channel.Can stasis-dispelling and pain-killing, promoting blood flow to regulate menstruation, lowering blood-fat and reducing weight, clear away heart-fire relieving restlessness.Radix Salviae Miltiorrhizae energy blood circulation promoting and blood stasis dispelling, removing obstruction in the collateral to relieve pain, nourish blood mind calming, can increase coronary heart disease blood flow, improve myocardial contraction, and not increase myocardial ischemia amount, promotes Doppler flow mapping and blood flow reallocation.It is the active drug of the treatment heart, brain, angiopathy, obesity and hyperlipemia.
Radix Panacis Quinquefolii; Saponin in Radix Panacis Quinquefolii effectively can strengthen nervus centralis; reach with all worries set aside with fixed attention, the effect such as allaying tiredness, memory reinforcing; also there is the effect of protection cardiovascular system; informal dress Radix Panacis Quinquefolii can arrhythmia, resist myocardial ischemia, anti-cardiac muscle oxidation, strengthening cardiac contractility ability; patients with coronary heart disease Symptoms is deficiency of both QI and YIN, palpitation and short breath can long-term taking Radix Panacis Quinquefolii, evident in efficacy.Effect of Radix Panacis Quinquefolii is also to regulate blood pressure, effectively can reduce temporary and persistency blood pressure, contribute to the recovery of the diseases such as hypertension, arrhythmia, coronary heart disease, acute myocardial infarction, cerebral thrombosis.
Rhizoma Corydalis, invigorate blood circulation, dissipating blood stasis, regulate the flow of vital energy, pain relieving; The all pains of main trusted subordinate's waist knee joint, menoxenia, lump in the abdomen, metrorrhagia, puerperal blood faints, lochiorrhea, traumatic injury.For the breast side of body, epigastric pain, amenorrhea dysmenorrhea, postpartum stagnation, tumbling and swelling.Rhizoma Corydalis principle active component is alkaloids, and processed product Rhizoma Corydalis (processed with vinegar) is the object of legal decoction pieces kind processed with vinegar is increase alkaloid, improves analgesic efficacy.The cardinal principle strengthening analgesic effect after Rhizoma Corydalis processed with vinegar is, acetic acid and alkaloid form solubility acetate, stripping when being beneficial to decoction.
Research proves, Radix Panacis Quinquefolii and Rhizoma Corydalis (processed with vinegar) compatibility benefiting QI for activating blood circulation effectively can treat myocardial ischemia, therefore may be used for preventing and/or treating coronary heart disease.
Radix Rehmanniae Preparata, sweet, tepor.Return liver, kidney channel.To enrich blood yin nourishing, life essence-filling, marrow-benefitting.Radix Rehmanniae Preparata can significantly suppress liver hemorrhagic necrosis stove and simple necrosis; To the hyperlipemia that high lipid food causes, the hepatic vein hemorrhage that fatty liver and rat endotoxin cause, all has the effect of inhibition thrombosis; To the activation of plasminogen, it is antithrombotic mechanism of action.
Fructus Corni, sour, puckery, tepor.Return liver, kidney channel.Liver and kidney tonifying, essence astringing and desertion stemming.For vertigo and tinnitus, soreness of waist and knee joint, impotence and seminal emission, enuresis frequent micturition, bleeding not during menses, profuse sweating is collapsed.Interior-heat is quenched one's thirst.The anti-stress ability of Fructus Corni energy enhancing body, improves mice anoxia enduring, anti-fatigue ability, memory reinforcing.It is active that Fructus Corni can improve SOD in erythrocyte, to anti peroxidation of lipid.Its ethanol extract also has effect for reducing blood fat, can reduce the content of serum triglycerides, cholesterol, arteriosclerosis.
Fructus Crataegi, sour in the mouth, sweet, slightly warm in nature.Return spleen, stomach, Liver Channel.Appetite-stimulating indigestion-relieving, change stagnant removing food stagnancy, promoting blood circulation to remove blood stasis, circulation of qi promoting of reducing phlegm.For meat stagnant long-pending, lump in the abdomen, abdominal distention feeling of fullness, stasis blocking stomachache, phlegm retention, have loose bowels, discharging fresh blood stool etc.Fructus Crataegi can significantly reduce serum cholesterol and triglyceride, effectively prevents and treats atherosclerosis; Fructus Crataegi also plays heart tonifying by strengthening myocardial contraction, increase cardiac output, coronary artery dilator blood vessel, increase coronary flow, reduction myocardial oxygen consumption etc. and prevents anginal effect.In addition, the total flavones in Fructus Crataegi has the effect of blood vessel dilating and lasting blood pressure lowering.
Gun additioner, pungent, hot greatly, poisonous.Enter the heart, spleen, kidney channel.Recuperating depleted YANG and rescuing the patient from collapse, warming the interior by cold, antalgic.Containing multiple alkaloid: hypaconitine (Hypa-conitine), aconitine (Aconitine), mesaconitine (Mesaconitine), talaisamine (Talatisamine), chuan-wu base A and chuan-wu base B etc.
Fructus Schisandrae Chinensis, temperature; Sour, sweet; Return lung, the heart, kidney channel.Restrain astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming.Fructus Schisandrae Chinensis has vasodilative effect.Schizandrin, schisandrin C, deoxyschisandrin etc. shrink in vitro Canis familiaris L. Mesenteric artery all inhibitory action, can increase arteries and veins Mus isolated heart and anesthesia Canis familiaris L. coronary flow.Fructus Schisandrae Chinensis is conducive to histiocytic oxygen exchange, can produce protective effect to heart tissue, also can palmic rate and relieve hypertension gently.
Ramulus Cinnamomi, acrid, sweet, warm.GUIXIN, lung, urinary bladder channel.Diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, the flat gas that spins.Blood vessel dilating, regulates blood circulation, makes blood flow to body surface, strengthens Herba Ephedrae perspiration.
Radix Angelicae Sinensis, warm in nature, hide sweet, pungent.Return liver, the heart, spleen channel.Enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.Radix Angelicae Sinensis can improve hypercoagulability in body, and adjustment blood lipid metabolism, reduces cholesterol.
The Radix Astragali, property is sweet, tepor.Return lung, spleen, liver, kidney channel.There is effect that benefiting QI for strengthening the superficies, arresting sweating are admittedly de-, hold in the palm skin ulcer granulation promoting, inducing diuresis to remove edema.The Radix Astragali can strengthen myocardial contraction, coronary artery dilating, improves myocardial blood flow and myocardial metabolism, improves superoxide dismutase activity, lowers lipid peroxide contents, thus alleviates the damage that free radical causes.
Radix Glycyrrhizae, property is put down, and sweet in the mouth, returns 12 warps.There is removing toxic substances, eliminate the phlegm, pain relieving, spasmolytic is so that the pharmacological action such as anticancer.Invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Rhizoma Chuanxiong, pungent, temperature.Return liver, gallbladder, pericardium channel.Blood-activating and qi-promoting, wind-expelling pain-stopping.For pacifying nerve, positive wind syndrome of head headache, lump in the abdomen is suffered from abdominal pain, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.Rhizoma Chuanxiong can expand smooth muscle, improves microcirculation, and has anticoagulant, resistant to aggregation effect, and the blood pressure lowering by expansion peripheral vessel.
Flos Lonicerae, sweet, cold.Attach to the lung and stomach meridians.Effect: heat-clearing and toxic substances removing.There is effect for reducing blood fat.
Medicine of the present invention is used for the treatment of coronary heart disease, not only can blood circulation promoting and blood stasis dispelling, coronary circulation-promoting pain-relieving, nourishing kidney can also nourish heart, there is blood fat reducing anticoagulant, reduce blood viscosity, thrombolytic effect, can also vascular endothelial function be improved, remove vasospasm, arteriosclerosis, stablizes vulnerable plaque; To blood, vascular lesion, there is double treatment effect.Through the display of clinical trial for many years, be used for the treatment of coronary heart disease, the diseases such as what Coronary Heart Disease Patients thrombosis can be made to cause feels oppressed, the nervous cardiopalmus that ischemia causes are eliminated.Take medicine about one week, symptom can obviously alleviate or disappear, and general about 30 days, can cure.Total effective rate more than 96%.The gentle easily clothes of the property of medicine, after drug withdrawal not " bounce-back ", short treating period, instant effect, cure rate be high, have no side effect, safe and reliable.
Detailed description of the invention
Below by embodiment and test example, the invention will be further described.But the present invention is not limited to described in embodiment, those of ordinary skill in the art do some amendment, all in scope.
Embodiment 1. 1 kinds treats the medicine of coronary heart disease, and each crude drug component proportion is: Radix Salviae Miltiorrhizae 10 grams, Radix Panacis Quinquefolii 10 grams, Rhizoma Corydalis (processed with vinegar) 10 grams, 20 grams, Radix Rehmanniae Preparata, Fructus Corni 10 grams, Fructus Crataegi 10 grams, gun additioner 5 grams, Fructus Schisandrae Chinensis 2 grams, Ramulus Cinnamomi 5 grams, Radix Angelicae Sinensis 10 grams, the Radix Astragali 15 grams, 5 grams, Radix Glycyrrhizae, Rhizoma Chuanxiong 5 grams, Flos Lonicerae 10 grams.
The raw material being more than one pair of powder is formed.During preparation, first prepare Rhizoma Corydalis (processed with vinegar), technique is: first corydalis tuber medicinal material is processed into granule, crosses 5 mesh sieves; Then add rice vinegar according to Corydalis Granule and rice vinegar weight ratio 5:1 to stir, place moistening.After rice vinegar is absorbed by medical material, put in pot and fry to micro-dry with slow fire, taking-up cools, and to obtain final product.Then moisture to Radix Angelicae Sinensis, Fructus Crataegi etc. many former medicine lyophilizations pulverized, each former medicine that water content is low is directly ground into fine powder again, and crosses 150 mesh sieves, i.e. obtained powder.Every day is early, middle and late takes 3 times, within one month, is a course for the treatment of.
Embodiment 2. 1 kinds treats the medicine of coronary heart disease, and each crude drug component proportion is: Radix Salviae Miltiorrhizae 30 grams, Radix Panacis Quinquefolii 20 grams, Rhizoma Corydalis (processed with vinegar) 20 grams, 50 grams, Radix Rehmanniae Preparata, Fructus Corni 20 grams, Fructus Crataegi 20 grams, gun additioner 10 grams, Fructus Schisandrae Chinensis 5 grams, Ramulus Cinnamomi 10 grams, Radix Angelicae Sinensis 25 grams, the Radix Astragali 30 grams, 10 grams, Radix Glycyrrhizae, Rhizoma Chuanxiong 15 grams, Flos Lonicerae 20 grams.
The raw material being more than one pair of Chinese patent medicine is formed.During preparation, Rhizoma Corydalis (processed with vinegar) technique and embodiment 1 are together.By total raw material by medicine: the Capacity Ratio of water is that 1:3 soaks at least 1h, add suitable quantity of water again and decoct 2h, elimination medicinal residues, under the condition of negative pressure, low temperature, the Chinese medicine leaching liquid of clarification being concentrated into Bomi degree is more than 75%, make dry powder (temperature≤100 DEG C of spout) by powder spraying apparatus, then add appropriate medical starch in dry powder after, be pressed into tablet (above is conventional Chinese drug preparation technique).Take every day 3 times (early, middle and late), each serving 4 ~ 6.It within one month, is a course for the treatment of.
Embodiment 3. 1 kinds treats the medicine of coronary heart disease, and each crude drug component proportion is: Radix Salviae Miltiorrhizae 20 grams, Radix Panacis Quinquefolii 15 grams, Rhizoma Corydalis (processed with vinegar) 15 grams, 30 grams, Radix Rehmanniae Preparata, Fructus Corni 15 grams, Fructus Crataegi 15 grams, gun additioner 7 grams, Fructus Schisandrae Chinensis 4 grams, Ramulus Cinnamomi 8 grams, Radix Angelicae Sinensis 20 grams, the Radix Astragali 20 grams, 6 grams, Radix Glycyrrhizae, Rhizoma Chuanxiong 10 grams, Flos Lonicerae 15 grams.
The raw material being more than one pair of medicament forms (during batch production, each component expands in proportion), and during preparation, Rhizoma Corydalis (processed with vinegar) technique and embodiment 1 are together.By medicine: the Capacity Ratio of water is that 1:2 soaks 1.5 hours, then add suitable quantity of water and decoct 1 hour, consider and remove medicinal residues, obtain medicinal liquid 150mL, after sterilizing, seal fill.Divide early, middle and late three clothes, each 50mL one month is a course for the treatment of.
Embodiment 4. 1 kinds treats the medicine of coronary heart disease, and each crude drug component proportion is: Radix Salviae Miltiorrhizae 15 grams, Radix Panacis Quinquefolii 12 grams, Rhizoma Corydalis (processed with vinegar) 18 grams, 20 grams, Radix Rehmanniae Preparata, Fructus Corni 20 grams, Fructus Crataegi 18 grams, gun additioner 9 grams, Fructus Schisandrae Chinensis 3 grams, Ramulus Cinnamomi 7 grams, Radix Angelicae Sinensis 20 grams, the Radix Astragali 20 grams, 8 grams, Radix Glycyrrhizae, Rhizoma Chuanxiong 8 grams, Flos Lonicerae 12 grams.
Preparation and instructions of taking are with embodiment 1.
Embodiment 5. 1 kinds treats the medicine of coronary heart disease, and each crude drug component proportion is: Radix Salviae Miltiorrhizae 25 grams, Radix Panacis Quinquefolii 15 grams, Rhizoma Corydalis (processed with vinegar) 14 grams, 40 grams, Radix Rehmanniae Preparata, Fructus Corni 13 grams, Fructus Crataegi 13 grams, gun additioner 8 grams, Fructus Schisandrae Chinensis 5 grams, Ramulus Cinnamomi 6 grams, Radix Angelicae Sinensis 22 grams, the Radix Astragali 27 grams, 9 grams, Radix Glycyrrhizae, Rhizoma Chuanxiong 11 grams, Flos Lonicerae 19 grams.
Preparation and instructions of taking are with embodiment 2.
Embodiment 6. 1 kinds treats the medicine of coronary heart disease, and each crude drug component proportion is: Radix Salviae Miltiorrhizae 22 grams, Radix Panacis Quinquefolii 14 grams, Rhizoma Corydalis (processed with vinegar) 13 grams, 45 grams, Radix Rehmanniae Preparata, Fructus Corni 20 grams, Fructus Crataegi 20 grams, gun additioner 5 grams, Fructus Schisandrae Chinensis 5 grams, Ramulus Cinnamomi 9 grams, Radix Angelicae Sinensis 17 grams, the Radix Astragali 28 grams, 6 grams, Radix Glycyrrhizae, Rhizoma Chuanxiong 10 grams, Flos Lonicerae 16 grams.
Preparation and instructions of taking are with embodiment 3.
Test example: the clinical observation of Drug therapy coronary heart disease of the present invention
1, ordinary circumstance
The present inventor accepts outpatient service patients with coronary heart disease totally 500 examples for nearly 6 years for medical treatment, wherein: man 200 example, female 300 example, 56.9 years old mean age.
2, Therapeutic Method
Every day oral medicine of the present invention, within 30 days, be a course for the treatment of, totally 2 courses for the treatment of, drug withdrawal is checked after half a year, and without recurrence for curing (effective), sb.'s illness took a favorable turn is evident as effectively, and it is not obvious that sb.'s illness took a favorable turn is invalid.
3, therapeutic outcome
Observe treatment 60 days, after following up a case by regular visits to half a year, therapeutic effect is in table 1.
Table 1
As can be seen here, curative effect of medication of the present invention is definite, and total effective rate reaches 96.8%.Show through clinical observation: medicine of the present invention has significant curative effect to heart diseases such as coronary heart diseases and angina pectoris, and curative effect is rapid, to angina pectoris, uncomfortable in chest, cardiopalmus, the symptom such as weak, patient generally take medicine once week after can feel obviously to alleviate or disappear, its electrocardiogram, blood pressure, blood fat, blood glucose etc. also obviously improve, to the Liver and kidney function of patient and hemopoietic system has no abnormal changes and untoward reaction, after drug withdrawal, the state of an illness does not occur " bounce-back ".
Model case:
Case 1: teacher, man, 60 years old.Paroxysmal stabbing pain over the chest 10 days, day at light night is heavy, uneasy sleeping at night, and with cardiovascular system symptoms, as cardiopalmus, tachycardia, perspires, stomach discomfort, and whole body weakness is dizzy etc.Take embodiment 1 medicine, continuously treatment 25 days, transference cure.
Case 2: field, female, 51 years old.Patient companion uncomfortable in chest in the heart paroxysmal pain for many years, takes: can not alleviate by Western medicine symptom for a long time; Recently increase the weight of, companion's cardiopalmus gas is few, fatigue and weakness, dynamic then pant; Electrocardiogram is pointed out: coronary insufficiency, and more than embodiment 2 medicine February, check electrocardiogram is completely normal.
Case 3: Liu, female, 62 years old.Sensation of oppression over the chest with shortness of breath more than 10 sky, within nearly 5 days, increase the weight of, chest pain radiating to the back, meets cool increasing the weight of, coolness of extremities.Take the medicine of embodiment 3, continuously treatment 30 days, transference cure.
Case 4: Zhu, man, 59 years old.Patient is compression pain before within 2002, starting to feel the heart, and with dizziness, cough, and the symptom such as be in a cold sweat.Through hospital's electrocardiogram report sinus rhythm acute coronary insufficiency.Often carry out mitigate the disease with the medicine such as dolantin, aminophylline.Patient have drink, smoking, bronchitis history, take embodiment 4 medicine one month, all diseases alleviate; Serve on three months, the symptoms such as angina pectoris have disappeared, Electrocardioscopy, recover normal.
Case 5: Nie, female, 68 years old.The relevant cardiopathia history of patient is had a surplus for 5 years, and feel uncomfortable in chest, breathe hard and aggravate the sense of chest tightness unhappiness, recurrent exerbation, Multiple Hospitalization is treated, poor effect.Take embodiment 5 medicine after 40 days, uncomfortable in chest, breathe hard, unhappy phenomenon obviously alleviates.Be used in conjunction two months, patient feels good, and through hospital's check after half a year, all are normal, do not recur.
Claims (4)
1. treat a medicine for coronary heart disease, it is characterized in that, each crude drug component is by weight ratio: Radix Salviae Miltiorrhizae 10-30 part, Radix Panacis Quinquefolii 10-20 part, Rhizoma Corydalis (processed with vinegar) 10-20 part, Radix Rehmanniae Preparata 20-50 part, Fructus Corni 10-20 part, Fructus Crataegi 10-20 part, gun additioner 5-10 part, Fructus Schisandrae Chinensis 2-5 part, Ramulus Cinnamomi 5-10 part, Radix Angelicae Sinensis 10-25 part, Radix Astragali 15-30 part, Radix Glycyrrhizae 5-10 part, Rhizoma Chuanxiong 5-15 part, Flos Lonicerae 10-20 part.
2. the medicine for the treatment of coronary heart disease according to claim 1, is characterized in that, each crude drug component is by weight ratio: Radix Salviae Miltiorrhizae 15-25 part, Radix Panacis Quinquefolii 12-15 part, Rhizoma Corydalis (processed with vinegar) 13-18 part, Radix Rehmanniae Preparata 30-40 part, Fructus Corni 13-15 part, Fructus Crataegi 13-18 part, gun additioner 5-8 part, Fructus Schisandrae Chinensis 3-5 part, Ramulus Cinnamomi 6-9 part, Radix Angelicae Sinensis 17-22 part, Radix Astragali 20-28 part, Radix Glycyrrhizae 6-9 part, Rhizoma Chuanxiong 8-11 part, Flos Lonicerae 12-16 part.
3. the medicine for the treatment of coronary heart disease according to claim 1, is characterized in that, each crude drug component is by weight ratio: Radix Salviae Miltiorrhizae 20 grams, Radix Panacis Quinquefolii 15 grams, Rhizoma Corydalis (processed with vinegar) 15 grams, 30 grams, Radix Rehmanniae Preparata, Fructus Corni 15 grams, Fructus Crataegi 15 grams, gun additioner 7 grams, Fructus Schisandrae Chinensis 4 grams, Ramulus Cinnamomi 8 grams, Radix Angelicae Sinensis 20 grams, the Radix Astragali 20 grams, 6 grams, Radix Glycyrrhizae, Rhizoma Chuanxiong 10 grams, Flos Lonicerae 15 grams.
4. prepare the method for the medicine of the arbitrary described treatment coronary heart disease of claim 1-3, it is characterized in that, during preparation, first by Rhizoma Corydalis processed with vinegar, preparation technology is: first corydalis tuber medicinal material is processed into granule, crosses 5 mesh sieves; Then add rice vinegar according to Corydalis Granule and rice vinegar weight ratio 5:1 to stir, place moistening; After rice vinegar is absorbed by medical material, put in pot and fry to micro-dry with slow fire, taking-up cools, and to obtain final product; Extract oral liquor, powder, tablet, capsule is prepared into further according to conventional Chinese medicine preparation method.
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|---|---|---|---|---|
| CN102210835B (en) * | 2011-06-10 | 2013-08-21 | 卢超忠 | Traditional Chinese medicine for treating coronary disease |
| CN102670973A (en) * | 2012-05-09 | 2012-09-19 | 成都绿迪科技有限公司 | Chinese medicinal formula for treating coronary disease through oral administration |
| CN103638428A (en) * | 2013-11-19 | 2014-03-19 | 青岛市市立医院 | Traditional Chinese medicinal composition for treating coronary heart disease |
-
2014
- 2014-04-29 CN CN201410174043.1A patent/CN103919910B/en not_active Expired - Fee Related
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