CN104547518A - Traditional Chinese medicine spray for preventing and treating acute heart failure and preparation method thereof - Google Patents
Traditional Chinese medicine spray for preventing and treating acute heart failure and preparation method thereof Download PDFInfo
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Abstract
The invention discloses traditional Chinese medicine spray for preventing and treating an acute heart failure. The traditional Chinese medicine spray is characterized by being prepared from the following main raw materials in parts by weight: 9-15 parts of arisaema erubescens, 6-12 parts of centella, 10-15 parts of kirilow rhodiola rhizome and root, 5-10 parts of dragon's bone , 6-12 parts of bluish dogbane, 50-70 parts of walnut kernel, 5-15 parts of glossy ganoderma, 4.5-9 parts of longan, 5-15 parts of lumbricus, 2-5 parts of astragalus membranaceus, 5-15 parts of radix salviae miltiorrhizae, 2-7 parts of cassia twig, 3-7 parts of colla corii asini and 5-10 parts of radix ophiopogonis. Through the use of the traditional Chinese medicine spray disclosed by the invention, symptoms of palpitation, the heart failure and emotional instability, which are caused by a pulmonary heart disease and a coronary heart disease, of a patient can be effectively relieved; for selected medicinal materials of the traditional Chinese medicine spray disclosed by the invention, according to the theoretical basis of Chinese traditional treatment for climacterium, the acute heart failure can be effectively prevented and treated, burdens of the patient and families of the patient are relieved, and the traditional Chinese medicine spray for preventing and treating the acute heart failure is safe and effective.
Description
Technical field
The invention belongs to traditional Chinese medicine field, especially relate to a kind of Traditional Chinese medicinal spray preventing and treating acute heart failure and preparation method thereof.
Background technology
Acute heart failure (AHF) refers to that acute attack or the myocardial contraction of left heart function caused by abnormal increased the weight of reduce, cardiac load increases the weight of, cause acute cardiac output rapid drawdown, pressure of pulmonary circulation raises, peripheral resistance increases, cause pulmonary circulation congested and occur that acute pulmonary venous pleonaemia, pulmonary edema also can accompany tissue, organ perfusion is not enough and the clinical syndrome of cardiogenic shock, the most common with left heart failure.Acute heart failure can on original chronic heart failure basis acute exacerbation or unexpected onset, premorbid most patients is associated with organic cardiovascular disease, can show as contractility heart failure, also can show as diastolic heart failure.The normal threat to life of acute heart failure, must promptly rescue.
Clinical manifestation 1. medical history and performance: Most patients has heart disease medical history, coronary heart disease, hypertension and senile degenerative heart valve disease are the Etiological of old people; Rheumatic valvular heart disease, dilated cardiomyopathy, acute severe myocarditis etc. are often youthful Etiological.2. risk factor: common inducement have chronic heart failure to treat to lack compliance, heart volume over loading, severe infections, serious head trauma evil or violent psychiatric nervous with fluctuation, major operation after, renal hypofunction, rapid heart rate is not normal, bronchial asthma attack, pulmonary infarction, high cardiac output syndrome, application negative inotropic action medicine, application nonsteroidal antiinflammatory drug, myocardial ischemia, older patients with acute diastolic function go down, take drugs, indulge in excessive drinking, pheochromocytoma etc.3. Early manifestation: the early stage sign that left heart function reduces is that the normal person of cardiac function occurs that tired, exercise tolerance obviously lowers, heart rate increases by 15 ~ 20 beats/min, then occurs exertional dyspnea, nocturnal paroxysmal dyspnea, high pillow sleep etc.; Check visible left ventricular enlargement, diastole gallop rhythm in early stage or mid-term, there are moist rale, dry rale and wheezing sound in two base of lung portions, the existing left heart function obstacle of prompting.4. acute lung edema: onset is anxious, and the state of an illness can develop rapidly to critical state.Severe dyspnea, the orthopnea of burst, gasp for breath, dysphoria have fear, respiratory frequency can reach 30 ~ 50 beats/min; Frequent cough also brings up a large amount of pink foam sample expectorant; Heart rate is fast, apex Chang Kewen and gallop rhythm; Two moist rale of fullness of the lung cloth and wheezing sounds.5. cardiogenic shock: (1) hypotension continues more than 30 minutes, and systolic pressure is down to below 90mmHg, or original hypertensive patient's systolic pressure reduction >=60mmHg.(2) tissue low perfusion state 1. skin clammy, pale and cyanosis companion purple fringe; 2. tachycardia > 110 beats/min; 3. urine volume obviously reduces (< 20ml/ hour), even anuria; 4. disturbance of consciousness, often has dysphoria, exciting anxiety, fear and dying sense; Systolic pressure, lower than 70mmHg, can occur suppressing symptom, be developed to confusion gradually and even go into a coma.(3) hemodynamics obstacle PCWP >=18mmHg, heart row's blood index (CI)≤36.7ml/s.m2 (≤2.2L/min.m2).(4) metabolic acidosis and hypoxemia.
In the technology of existing traditional Chinese medicine field control acute heart failure, the patent document of Authorization Notice No. CN 102145089 B (application number 201210113893.1) discloses a kind of oral traditional Chinese medicine preparation for the treatment of postcerebral injury syndrome, it is characterized in that adopting the raw material of Chinese medicine of following weight parts to make: the Radix Astragali 10 ± 2, Radix Panacis Quinquefolii 10 ± 2, Radix Angelicae Sinensis 10 ± 2, Fructus Lycii 10 ± 2, Radix Salviae Miltiorrhizae 10 ± 2, Ganoderma 10 ± 2, Radix Paeoniae Rubra 10 ± 2, Semen Persicae 10 ± 2, Poria 10 ± 2, Pericarpium Citri Reticulatae 10 ± 2, Semen Plantaginis 10 ± 2, Concretio Silicea Bambusae 10 ± 2, Rhizoma Acori Graminei 10 ± 2, Rhizoma Gastrodiae 10 ± 2, Ramulus Uncariae Cum Uncis 10 ± 2, Semen Ziziphi Spinosae 10 ± 2, Succinum powder 10 ± 2, process Rhizoma Rhodiolae kirilowii 6 ± 1.2.The Chinese patent of Authorization Notice No. CN 103007089 B (application number 201310009705.5) disclose a kind of treat craniocerebral trauma after the Chinese medicine composition of concurrent stress ulcer, it is characterized in that, this Chinese medicine composition is made up of the medicine of following weight portion: Radix Cirsii Japonici 10-20 part, Herba Cirsii 10-20 part, charred Petiolus Trachycarpi 10-20 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 25-35 part, Radix Et Rhizoma Rhei 4-14 part, Radix Notoginseng powder 3-9 part, Semen Juglandis 25-35 part and Herba Agrimoniae 25-35 part.
As can be seen here, Chinese medicine obtains good curative effect improving in cerebral trauma, but in existing patent, operation trouble is refined in processing, and cost is higher, is not suitable for poor family and uses.
Summary of the invention
For the deficiency of existing control acute heart failure present situation, an object of the present invention is to provide a kind of Traditional Chinese medicinal spray preventing and treating acute heart failure, there is easy to operate, evident in efficacy, sufferer and bear painful little feature, and its adopts Chinese crude drug comparatively common in the localities as raw material, with low cost.
Another object of the present invention is just to provide the preparation method of above-mentioned control acute heart failure Traditional Chinese medicinal spray.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
Prevent and treat a Traditional Chinese medicinal spray for acute heart failure, take off the primary raw material stating weight proportion and be prepared from: Rhizoma Arisaematis 9-15 part, Herba Centellae 6-12 part, Rhizoma Rhodiolae kirilowii 10-15 part, Os Draconis 5-10 part, Herba Apocyni veneti 6-12 part, Semen Juglandis 50-70 part, Ganoderma 5-15 part, Arillus Longan 4.5-9 part, Pheretima 5-15 part, Radix Astragali 2-5 part, Radix Salviae Miltiorrhizae 5-15 part, Ramulus Cinnamomi 2-7 part, Colla Corii Asini 3-7 part, Radix Ophiopogonis 5-10 part.
The Traditional Chinese medicinal spray of above-mentioned control acute heart failure, takes off the primary raw material stating weight proportion and is prepared from: Rhizoma Arisaematis 10-12 part, Herba Centellae 7-10 part, Rhizoma Rhodiolae kirilowii 11-14 part, Os Draconis 6-9 part, Herba Apocyni veneti 9-11 part, Semen Juglandis 55-65 part, Ganoderma 8-11 part, Arillus Longan 5-8 part, Pheretima 7-12 part, Radix Astragali 3-4 part, Radix Salviae Miltiorrhizae 7-12 part, Ramulus Cinnamomi 3-6 part, Colla Corii Asini 4-6 part, Radix Ophiopogonis 6-9 part.
The Traditional Chinese medicinal spray of above-mentioned control acute heart failure, takes off the primary raw material stating weight proportion and is prepared from: Rhizoma Arisaematis 10 parts, Herba Centellae 8 parts, Rhizoma Rhodiolae kirilowii 12 parts, Os Draconis 8 parts, Herba Apocyni veneti 10 parts, Semen Juglandis 60 parts, Ganoderma 10 parts, Arillus Longan 6.5 parts, Pheretima 10 parts, the Radix Astragali 3.5 parts, Radix Salviae Miltiorrhizae 10 parts, Ramulus Cinnamomi 5 parts, 5 parts, Colla Corii Asini, Radix Ophiopogonis 7 parts.
Prevent and treat a preparation method for the Traditional Chinese medicinal spray of acute heart failure, specifically have following steps to be prepared from:
1. Os Draconis are smashed, be placed on smokeless stove fire, burn and make the carbonization of medical surfaces part to outside burned black for spending, then grind to form smalls, cross 60-100 mesh sieve stand-by;
2. be divided into two by Pheretima, clean, with the slightly vexed 10-20 minute of Chinese liquor, be placed in the hot pot that dryouies, repeatedly stir-fry to crisp, it is stand-by to grind to form smalls;
3. clear water is placed in marmite, Colla Corii Asini is added after big fire is boiled, the Rhizoma Arisaematis of clean chopping, Herba Centellae, Rhizoma Rhodiolae kirilowii, Herba Apocyni veneti, Ganoderma, Arillus Longan, the Radix Astragali, Radix Salviae Miltiorrhizae, Ramulus Cinnamomi and Radix Ophiopogonis is added after Colla Corii Asini melts completely, while stir infusion on one side with large ferrum spoon, add after filtrate is boiled step 1. with step 2. gained smalls, after intense fire is fried open, cover seal cover, turn slow fire boiling 60-90 minute, sealing and standing 3-5 hour, get supernatant stand-by;
4. Semen Juglandis is placed in and burns on hot clean iron plate, when Semen Juglandis is dried to crisp, grind to form smalls, cross 80-120 mesh sieve;
5. by step 3. gained supernatant add step 4. gained walnut powder after being heated to 80 DEG C, until boiling after 10 minutes, dry heat sterilization 3-8 minute at 120-140 DEG C, is sealed in after cooling in plastic bottle, obtains Traditional Chinese medicinal spray.
The preparation method of above-mentioned Traditional Chinese medicinal spray, preparation process 1. smalls crosses 70-90 mesh sieve stand-by (preferred, it is stand-by that smalls crosses 80 mesh sieves).
The preparation method of above-mentioned Traditional Chinese medicinal spray, the consumption of preparation process 2. Chinese liquor be the 1-3 of Pheretima weight doubly (preferred, the consumption of Chinese liquor be the 1.5-2.5 of Pheretima weight doubly, be more preferably, the consumption of Chinese liquor is 2 times of Pheretima weight).
The preparation method of above-mentioned Traditional Chinese medicinal spray, preparation process is 2. with slightly vexed 13-18 minute of Chinese liquor (preferred, with Chinese liquor slightly vexed 15 minutes).
The preparation method of above-mentioned Traditional Chinese medicinal spray, 3. preparation process turns slow fire boiling 70-80 minute, sealing and standing 3.5-4.5 hour (preferred, to turn slow fire boiling 75 minutes, sealing and standing 4 hours).
The preparation method of above-mentioned Traditional Chinese medicinal spray, preparation process 5. at 125-135 DEG C dry heat sterilization 5-7 minute (preferred, dry heat sterilization 6 minutes at 130 DEG C).
Using method: one for several times, under getting Traditional Chinese medicinal spray of the present invention spray 3-8,10 days is a course for the treatment of at every turn.
This Traditional Chinese medicinal spray, to control acute heart failure Be very effective, has pain relieving, reinforcing the heart, calms the nerves, controls dizzy effect.
The pharmacological effect of each crude drug is respectively:
Rhizoma Arisaematis: base is former: for Bryaceae rhodobryum spp plant warms up the plant of ground great Ye moss.Composition: plant contains volatile oil, flavonoid, steroidal, aminoacid, saccharide, glycoside, terpenoid etc.The property of medicine: pungent, bitter, flat.Function cures mainly: tranquilizing by nourishing the heart, liver heat removing and eyesight improving.Cure mainly severe palpitation, neurasthenia, conjunctival congestion and swelling pain, coronary heart disease etc.
Herba Centellae: base is former: be dry herb or the whole herb with root of dicotyledon Umbelliferae Herba Centellae.Composition: containing the Triterpenoid of multiple α-balsam alcohol type, wherein have asiaticoside, thankuniside, isothankuniside, asiaticoside, Brahmoside, broken hot rice glycosides and Brahmic acid etc., and madasiatic acid.The property of medicine: bitter, acrid, cold.Return liver,spleen,kidney warp.Function cures mainly: heat-clearing and toxic substances removing, inducing diuresis and reducing edema.Be the long-lived medicine of Asians, can refresh oneself by beneficial brain.Research shows to have nourishing, antiinflammatory, healing of wound, diuresis relieving constipation and calm effect.Also effective in cure to leprosy, ulcer, there is activation to blood purification and immunity, because it can stimulate the replacement of deep skin cell.It is neural nourishing agent, can improve memory, alleviate mental fatigue; Also can blood pressure lowering, treatment hepatopathy etc.
Rhizoma Rhodiolae kirilowii: base is former: be the root and rhizome of Crassulaceae Rhodida plant Rhodiola kirilowii (Regel) Maxim..Composition: herb is containing butyl alcohol, and daucosterol, rhodioside, hundred arteries and veins are with glycosides.The property of medicine: bitter, puckery, temperature.Return lung, the heart, liver, large intestine channel.Function cures mainly: tranquilizing by nourishing the heart, blood stasis dispelling, hemostasis.Cure mainly deficiency of vital energy and physically weak, weak palpitation and insomnia of losing heart, dizzy dizzy, pain uncomfortable in chest, traumatic injury, menoxenia, metrorrhagia, spits blood, dysentery, diarrhoea.
Os Draconis: base is former: for mammal in ancient times resembles the Skeletal Fossils of class, rhinoceros class, Hippocampal cortex, bovine, deer class etc.Composition: Os Draconis, mainly containing calcium carbonate and calcium phosphate, still contain ferrum, potassium, sodium, chlorine, sulfate radical etc.The property of medicine: puckery, sweet, flat.GUIXIN, liver, kidney, large intestine channel.Function cures mainly: tranquilizing mind, suppressing the hyperactive liver and subsiding YANG, restrains astringent or styptic treatment for spontaneous sweating.Cure mainly cardiopalmus, seized with terror swollen, insomnia, forgetful, infantile convulsion, demented, dizzy, spontaneous sweating, the seminal emission enuresis, bleeding not during menses, chronic diarrhea and dysentery, ulcer does not close up and eczema for a long time.
Herba Apocyni veneti: base is former: be the leaf of Apocynaceae Apocynum plant Herba Apocyni veneti.Composition: leaf contains Quercetin, isoquercitrin, hyperin, Trifolin, cloud English glycosides, rutin, cianidanol, anthraquinone, and the several amino acids such as glutamic acid, alanine.The property of medicine: sweet, micro-hardship, cool.Function cures mainly: heat clearing away, and suppressing the hyperactive liver is calmed the nerves, diuretic.Cure mainly high blood Os Draconis pressure sick, dizzy, headache, cardiopalmus, insomnia, edema oliguria.
Semen Juglandis: brain-strengthening is anti-old: Semen Juglandis contains more protein and the required unsaturated fatty acid of human nutrition, and these compositions are all the important substance of cerebral tissue cellular metabolism, can nursing brain cells, cerebral function improvement.To releive fatigue, resistance to compression.Purify the blood, reduce cholesterol: Semen Juglandis can reduce the absorption of intestinal to cholesterol.And solubilized cholesterol, " the dirt impurity " got rid of in blood vessel wall makes blood purification, thus provides better fresh blood for human body.So Semen Juglandis prevents arteriosclerosis, reduce the effect of cholesterol.In addition, Semen Juglandis also can be used for treating non-insulin-dependent diabetes mellitus.
Ganoderma: Ganoderma profile is umbrella, cap kidney shape, semicircle or subcircular are the sporophore of On Polyporaceae Ganoderma.There is effect of invigorating QI and tranquilization, relieving cough and asthma, for dizzy sleeplessness, shortness of breath and palpitation, asthenia cough with asthma.Malaise, insomnia, palpitation with fear.This product sweet in the mouth is put down, and enters heart channel, can reinforcing the heart blood, the beneficial motive, tranquilizing mind, therefore availablely controls the disease such as malaise caused by insufficiency of vital energy and blood, lack of preservation of spirit, insomnia, palpitation with fear, dreaminess, forgetful, the tired Mental fatigue of body, lack of appetite.
Arillus Longan: reinforcing the heart spleen, replenishing QI and blood, strengthening the spleen and stomach, supports muscle.Worry impairing spleen, dizzy, insomnia, severe palpitation, emptyly wins, and after being ill or puerperal asthenia, and to lose blood disease due to insufficiency of the spleen caused hematochezia.Modem medical practices proves, it also has effect of beauty treatment, life lengthening.
Pheretima: calentura mania and irritation, infantile convulsion, cough with asthma, headache conjunctival congestion, laryngopharynx swelling and pain, urinary obstruction, Fengshi Guanjie pain, hemiplegia LUMBRICUS is dry waits disease.External is coated with the disease such as erysipelas, dermatitis rhus.1. clearing heat for calming endogenous wind: cure mainly high fever infantile convulsion, wind symptom is twitched.2. lung-clearing asthma-relieving: the asthma of lung-heat productive cough can be controlled, better to lung heat type bronchial asthma curative effect.3. inducing diuresis for treating stranguria syndrome: be applicable to damp invasion of lower energizer, the puckery pain of pyretic stranguria.4. current meridians: available pyretic arthralgia of controlling saves swollen swelling pain; Suitable compatibility also can control arthralgia due to cold; Compatibility replenishing qi and promoting blood flow medicine is usually used in blood stasis due to qi deficiency, and meridians are unfavorable, aphasia hemiplegia person.
The Radix Astragali: astragalus root is used as medicine, raw use, promoting blood circulation to restore menstrual flow; Control puerperal abdonimal pain, menoxenia, amenorrhea, epistaxis toothache caused by fire of deficiency type, beriberi edema; Ripe use, invigorating the liver and kidney, strong waist knee joint; Control soreness of waist and knee joint, caused by liver and kidney deficiency, traumatic injury stasis of blood pain.Veterinary, as controlling cattle weak foot disease, gets injured by a fall knochenbruch etc.
Radix Salviae Miltiorrhizae: nature and flavor are bitter, are slightly cold.GUIXIN, Liver Channel.There is stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, the effect of the relieving restlessness that clears away heart-fire.For menoxenia, amenorrhea dysmenorrhea, lump in the abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia; Hepatosplenomegaly, angina pectoris.
Ramulus Cinnamomi: acrid, sweet, warm.GUIXIN, lung, urinary bladder channel.There is diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, effect of the flat gas that spins.Be usually used in anemofrigid cold, coldness and pain in the epigastrium, cold in blood amenorrhea, arthralgia, phlegm retention, edema, cardiopalmus etc.
Colla Corii Asini: temperature compensation Liver and kidney, beneficial intensive culture blood.Dizzy for blood deficiency, the acid of waist knee joint is cold, and asthenia is become thin.
Radix Ophiopogonis: this product has more significant analgesic activity, headed by Radix Ophiopogonis, the uterus ball of taste medicine antibacterially have stronger bacteriostasis than multiple, and effectively can kill infusorian, regulating qi and activating blood, analgesic therapy, chases after poison.Control coagulation of QI-blood, trusted subordinate's pain, carbuncle pyogenic infections from tumour or sore, traumatic injury, dysmenorrhea, postnatal blood stasis twinge.
Traditional Chinese medicinal spray of the present invention debates the principle of disease treatment based on Chinese medicine.The medical material selected has for showing disease pain relieving, reinforcing the heart, calming the nerves, and Main Function is blood circulation promoting and blood stasis dispelling, damp eliminating detumescence, tranquillizing and allaying excitement; Still there is the effect such as Qi-benefiting and heart-nourishing, eliminating phlegm and calming wind in addition, take into account inside and outside belonging to and medicine safely and effectively, have fabulous therapeutical effect to control acute heart failure.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
Embodiment 1 one kinds prevents and treats the Traditional Chinese medicinal spray of acute heart failure, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Rhizoma Arisaematis 9 parts, Herba Centellae 6 parts, Rhizoma Rhodiolae kirilowii 10 parts, Os Draconis 5 parts, Herba Apocyni veneti 6 parts, Semen Juglandis 50 parts, Ganoderma 5 parts, Arillus Longan 4.5 parts, Pheretima 5 parts, the Radix Astragali 2 parts, Radix Salviae Miltiorrhizae 5 parts, Ramulus Cinnamomi 2 parts, 3 parts, Colla Corii Asini, Radix Ophiopogonis 5 parts.
The preparation method of the Traditional Chinese medicinal spray of above-mentioned control acute heart failure, step is as follows:
1. Os Draconis are smashed, be placed on smokeless stove fire, burn and make the carbonization of medical surfaces part to outside burned black for spending, then grind to form smalls, cross 60 mesh sieves stand-by;
2. be divided into two by Pheretima, clean, with Chinese liquor slightly vexed 10 minutes, the consumption of Chinese liquor is 1 times of Pheretima weight, is placed in the hot pot that dryouies, repeatedly stir-fries to crisp, and it is stand-by to grind to form smalls;
3. clear water is placed in marmite, Colla Corii Asini is added after big fire is boiled, the Rhizoma Arisaematis of clean chopping, Herba Centellae, Rhizoma Rhodiolae kirilowii, Herba Apocyni veneti, Ganoderma, Arillus Longan, the Radix Astragali, Radix Salviae Miltiorrhizae, Ramulus Cinnamomi and Radix Ophiopogonis is added after Colla Corii Asini melts completely, while stir infusion on one side with large ferrum spoon, add after filtrate is boiled step 1. with step 2. gained smalls, after intense fire is fried open, cover seal cover, turn slow fire boiling 60 minutes, sealing and standing 3 hours, gets supernatant stand-by;
4. Semen Juglandis is placed in and burns on hot clean iron plate, when Semen Juglandis is dried to crisp, grind to form smalls, cross 80 mesh sieves;
5. by step 3. gained supernatant add step 4. gained walnut powder after being heated to 80 DEG C, until boiling after 10 minutes, at 120 DEG C, dry heat sterilization 3 minutes, is sealed in after cooling in plastic bottle, obtains Traditional Chinese medicinal spray.
Model case one Zhu XX, man, 42 years old, Dezhou, Shandong Province personage, patient had asthma medical history more than 3 year, often coughs at ordinary times, and feels asthma, out of breath and feel suffocated.In January, 2006 unexpected exacerbation of symptoms, sweating due to debility is dripping, lower limbs edema, and green around the gills emergency treatment is rescued at local hospital, at that time cardiac function level Four, Color Sonography prompting expand whole-heartedly, heart failure, lung A high pressure.Because the state of an illness is critical, local doctor informs that patient treatment wishes not quite, to remove examination in hospital, and doctor advised uses Traditional Chinese medicinal spray of the present invention.
Use the Traditional Chinese medicinal spray of embodiment 1 gained, use 4 days, malaise symptoms disappears substantially, continues to take 2 weeks, removes examination in hospital, and self-induction is fully recovered.Take 15 days, precordialgia, cough alleviate, and fatigue and weak also alleviates, and the amount of receiving increases, spirit can, take 5 months, the coronary artery blood supply of electrocardio diagram obviously improves, and patient's self-induction is fully recovered.
Embodiment 2 one kinds prevents and treats the Traditional Chinese medicinal spray of acute heart failure, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Rhizoma Arisaematis 15 parts, Herba Centellae 12 parts, Rhizoma Rhodiolae kirilowii 15 parts, Os Draconis 10 parts, Herba Apocyni veneti 12 parts, Semen Juglandis 70 parts, Ganoderma 15 parts, Arillus Longan 9 parts, Pheretima 15 parts, the Radix Astragali 5 parts, Radix Salviae Miltiorrhizae 15 parts, Ramulus Cinnamomi 7 parts, 7 parts, Colla Corii Asini, Radix Ophiopogonis 10 parts.
The preparation method of the Traditional Chinese medicinal spray of above-mentioned control acute heart failure, step is as follows:
1. Os Draconis are smashed, be placed on smokeless stove fire, burn and make the carbonization of medical surfaces part to outside burned black for spending, then grind to form smalls, cross 100 mesh sieves stand-by;
2. be divided into two by Pheretima, clean, with Chinese liquor slightly vexed 20 minutes, the consumption of Chinese liquor is 3 times of Pheretima weight, is placed in the hot pot that dryouies, repeatedly stir-fries to crisp, and it is stand-by to grind to form smalls;
3. clear water is placed in marmite, Colla Corii Asini is added after big fire is boiled, the Rhizoma Arisaematis of clean chopping, Herba Centellae, Rhizoma Rhodiolae kirilowii, Herba Apocyni veneti, Ganoderma, Arillus Longan, the Radix Astragali, Radix Salviae Miltiorrhizae, Ramulus Cinnamomi and Radix Ophiopogonis is added after Colla Corii Asini melts completely, while stir infusion on one side with large ferrum spoon, add after filtrate is boiled step 1. with step 2. gained smalls, after intense fire is fried open, cover seal cover, turn slow fire boiling 90 minutes, sealing and standing 5 hours, gets supernatant stand-by;
4. Semen Juglandis is placed in and burns on hot clean iron plate, when Semen Juglandis is dried to crisp, grind to form smalls, cross 120 mesh sieves;
5. by step 3. gained supernatant add step 4. gained walnut powder after being heated to 80 DEG C, until boiling after 10 minutes, at 140 DEG C, dry heat sterilization 8 minutes, is sealed in after cooling in plastic bottle, obtains Traditional Chinese medicinal spray.
Embodiment 3 one kinds prevents and treats the Traditional Chinese medicinal spray of acute heart failure, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Rhizoma Arisaematis 10 parts, Herba Centellae 7 parts, Rhizoma Rhodiolae kirilowii 11 parts, Os Draconis 6 parts, Herba Apocyni veneti 9 parts, Semen Juglandis 55 parts, Ganoderma 8 parts, Arillus Longan 5 parts, Pheretima 7 parts, the Radix Astragali 3 parts, Radix Salviae Miltiorrhizae 7 parts, Ramulus Cinnamomi 3 parts, 4 parts, Colla Corii Asini, Radix Ophiopogonis 6 parts.
The preparation method of the Traditional Chinese medicinal spray of above-mentioned control acute heart failure, step is as follows:
1. Os Draconis are smashed, be placed on smokeless stove fire, burn and make the carbonization of medical surfaces part to outside burned black for spending, then grind to form smalls, cross 70 mesh sieves stand-by;
2. be divided into two by Pheretima, clean, with Chinese liquor slightly vexed 13 minutes, the consumption of Chinese liquor is 1.5 times of Pheretima weight, is placed in the hot pot that dryouies, repeatedly stir-fries to crisp, and it is stand-by to grind to form smalls;
3. clear water is placed in marmite, Colla Corii Asini is added after big fire is boiled, the Rhizoma Arisaematis of clean chopping, Herba Centellae, Rhizoma Rhodiolae kirilowii, Herba Apocyni veneti, Ganoderma, Arillus Longan, the Radix Astragali, Radix Salviae Miltiorrhizae, Ramulus Cinnamomi and Radix Ophiopogonis is added after Colla Corii Asini melts completely, while stir infusion on one side with large ferrum spoon, add after filtrate is boiled step 1. with step 2. gained smalls, after intense fire is fried open, cover seal cover, turn slow fire boiling 70 minutes, sealing and standing 3.5 hours, gets supernatant stand-by;
4. Semen Juglandis is placed in and burns on hot clean iron plate, when Semen Juglandis is dried to crisp, grind to form smalls, cross 90 mesh sieves;
5. by step 3. gained supernatant add step 4. gained walnut powder after being heated to 80 DEG C, until boiling after 10 minutes, at 125 DEG C, dry heat sterilization 5 minutes, is sealed in after cooling in plastic bottle, obtains Traditional Chinese medicinal spray.
Embodiment 4 one kinds prevents and treats the Traditional Chinese medicinal spray of acute heart failure, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Rhizoma Arisaematis 12 parts, Herba Centellae 10 parts, Rhizoma Rhodiolae kirilowii 14 parts, Os Draconis 9 parts, Herba Apocyni veneti 11 parts, Semen Juglandis 65 parts, Ganoderma 11 parts, Arillus Longan 8 parts, Pheretima 12 parts, the Radix Astragali 4 parts, Radix Salviae Miltiorrhizae 12 parts, Ramulus Cinnamomi 6 parts, 6 parts, Colla Corii Asini, Radix Ophiopogonis 9 parts.
The preparation method of the Traditional Chinese medicinal spray of above-mentioned control acute heart failure, step is as follows:
1. Os Draconis are smashed, be placed on smokeless stove fire, burn and make the carbonization of medical surfaces part to outside burned black for spending, then grind to form smalls, cross 90 mesh sieves stand-by;
2. be divided into two by Pheretima, clean, with Chinese liquor slightly vexed 18 minutes, the consumption of Chinese liquor is 2.5 times of Pheretima weight, is placed in the hot pot that dryouies, repeatedly stir-fries to crisp, and it is stand-by to grind to form smalls;
3. clear water is placed in marmite, Colla Corii Asini is added after big fire is boiled, the Rhizoma Arisaematis of clean chopping, Herba Centellae, Rhizoma Rhodiolae kirilowii, Herba Apocyni veneti, Ganoderma, Arillus Longan, the Radix Astragali, Radix Salviae Miltiorrhizae, Ramulus Cinnamomi and Radix Ophiopogonis is added after Colla Corii Asini melts completely, while stir infusion on one side with large ferrum spoon, add after filtrate is boiled step 1. with step 2. gained smalls, after intense fire is fried open, cover seal cover, turn slow fire boiling 80 minutes, sealing and standing 4 hours, gets supernatant stand-by;
4. Semen Juglandis is placed in and burns on hot clean iron plate, when Semen Juglandis is dried to crisp, grind to form smalls, cross 110 mesh sieves;
5. by step 3. gained supernatant add step 4. gained walnut powder after being heated to 80 DEG C, until boiling after 10 minutes, at 135 DEG C, dry heat sterilization 7 minutes, is sealed in after cooling in plastic bottle, obtains Traditional Chinese medicinal spray.
Model case two: ancient sacrificial utensil XX, female, 60 years old, Jinan, Shandong Province personage.Precordial dull pain is had a surplus for 2 years, and every day, panic attacks 2-5 time, could alleviate containing nitroglycerin.Have uncomfortable in chest, be afraid of cold, cardiopalmus, extremities being not warm be warm, fatigue and weak, lower limb swells the diseases such as the soreness of waist, chest pain radiating to the back.Electrocardio diagram coronary insufficiency.B ultrasonic display merges ventricular aneurysm.Deep-slow pulse, white and thin fur.Household fears that patient causes acute heart failure, removes examination in hospital, its use of doctor advised gained Traditional Chinese medicinal spray of the present invention.
Use the Traditional Chinese medicinal spray of embodiment 4 gained, take 21 days, precordialgia obviously alleviates, and fatigue and weak also alleviates, and the amount of receiving increases, spirit can, take 1 month, the blood supply of electrocardio diagram coronary artery obviously improves, and following the service 4 months, patient fully recovers.
Embodiment 5 one kinds prevents and treats the Traditional Chinese medicinal spray of acute heart failure, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Rhizoma Arisaematis 10 parts, Herba Centellae 8 parts, Rhizoma Rhodiolae kirilowii 12 parts, Os Draconis 8 parts, Herba Apocyni veneti 10 parts, Semen Juglandis 60 parts, Ganoderma 10 parts, Arillus Longan 6.5 parts, Pheretima 10 parts, the Radix Astragali 3.5 parts, Radix Salviae Miltiorrhizae 10 parts, Ramulus Cinnamomi 5 parts, 5 parts, Colla Corii Asini, Radix Ophiopogonis 7 parts.
The preparation method of the Traditional Chinese medicinal spray of above-mentioned control acute heart failure, step is as follows:
1. Os Draconis are smashed, be placed on smokeless stove fire, burn and make the carbonization of medical surfaces part to outside burned black for spending, then grind to form smalls, cross 80 mesh sieves stand-by;
2. be divided into two by Pheretima, clean, with Chinese liquor slightly vexed 15 minutes, the consumption of Chinese liquor is 2 times of Pheretima weight, is placed in the hot pot that dryouies, repeatedly stir-fries to crisp, and it is stand-by to grind to form smalls;
3. clear water is placed in marmite, Colla Corii Asini is added after big fire is boiled, the Rhizoma Arisaematis of clean chopping, Herba Centellae, Rhizoma Rhodiolae kirilowii, Herba Apocyni veneti, Ganoderma, Arillus Longan, the Radix Astragali, Radix Salviae Miltiorrhizae, Ramulus Cinnamomi and Radix Ophiopogonis is added after Colla Corii Asini melts completely, while stir infusion on one side with large ferrum spoon, add after filtrate is boiled step 1. with step 2. gained smalls, after intense fire is fried open, cover seal cover, turn slow fire boiling 75 minutes, sealing and standing 4 hours, gets supernatant stand-by;
4. Semen Juglandis is placed in and burns on hot clean iron plate, when Semen Juglandis is dried to crisp, grind to form smalls, cross 100 mesh sieves;
5. by step 3. gained supernatant add step 4. gained walnut powder after being heated to 80 DEG C, until boiling after 10 minutes, at 130 DEG C, dry heat sterilization 6 minutes, is sealed in after cooling in plastic bottle, obtains Traditional Chinese medicinal spray.
Test example: the clinical practice of Traditional Chinese medicinal spray of embodiment 5 gained control acute heart failure: in June, 2008 in December ,-2011, screen 200 routine patients in 4 hospitals, wherein women 100 example, male 100 example, oldest 72 years old, minimal ages 40 years old, 55 years old mean age.Before test 1 week, Continuous Observation is carried out to this crowd, record symptom and change, be divided into two groups at random, experimental group and matched group, experimental group takes embodiment 5 products obtained therefrom, matched group takes other medicine, the criterion of curative effect situation: cure: after using this product, and malaise symptoms disappears; Effective: after using this product, malaise symptoms alleviates or partial disappearance; Invalid: use a course for the treatment of of this product, malaise symptoms is unchanged.Result is as shown in table 1.
Table 1: take embodiment 5 product 40-72 year control acute heart failure patient treatment outcome
Therapeutic effect: cure 95 examples (95%), effective 3 examples (3%), invalid 2 examples (2%), total effective rate 98%.Successful is better than matched group.
Prove through clinical trial, use Traditional Chinese medicinal spray of the present invention, effectively can alleviate and be caused by pulmonary heart disease, patients with coronary heart disease, the symptom of cardiopalmus, heart failure and emotional instability, the medical material that Traditional Chinese medicinal spray of the present invention is selected is according to the involutional theoretical basis of Chinese traditional treatment, can effectively preventing acute heart failure, alleviating the burden of patient and household thereof, is a kind of Traditional Chinese medicinal spray preventing and treating acute heart failure safely and effectively.
Claims (9)
1. prevent and treat a Traditional Chinese medicinal spray for acute heart failure, it is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Rhizoma Arisaematis 9-15 part, Herba Centellae 6-12 part, Rhizoma Rhodiolae kirilowii 10-15 part, Os Draconis 5-10 part, Herba Apocyni veneti 6-12 part, Semen Juglandis 50-70 part, Ganoderma 5-15 part, Arillus Longan 4.5-9 part, Pheretima 5-15 part, Radix Astragali 2-5 part, Radix Salviae Miltiorrhizae 5-15 part, Ramulus Cinnamomi 2-7 part, Colla Corii Asini 3-7 part, Radix Ophiopogonis 5-10 part.
2. the Traditional Chinese medicinal spray of control acute heart failure according to claim 1, is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Rhizoma Arisaematis 10-12 part, Herba Centellae 7-10 part, Rhizoma Rhodiolae kirilowii 11-14 part, Os Draconis 6-9 part, Herba Apocyni veneti 9-11 part, Semen Juglandis 55-65 part, Ganoderma 8-11 part, Arillus Longan 5-8 part, Pheretima 7-12 part, Radix Astragali 3-4 part, Radix Salviae Miltiorrhizae 7-12 part, Ramulus Cinnamomi 3-6 part, Colla Corii Asini 4-6 part, Radix Ophiopogonis 6-9 part.
3. the Traditional Chinese medicinal spray of control acute heart failure according to claim 1, is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Rhizoma Arisaematis 10 parts, Herba Centellae 8 parts, Rhizoma Rhodiolae kirilowii 12 parts, Os Draconis 8 parts, Herba Apocyni veneti 10 parts, Semen Juglandis 60 parts, Ganoderma 10 parts, Arillus Longan 6.5 parts, Pheretima 10 parts, the Radix Astragali 3.5 parts, Radix Salviae Miltiorrhizae 10 parts, Ramulus Cinnamomi 5 parts, 5 parts, Colla Corii Asini, Radix Ophiopogonis 7 parts.
4. the preparation method of the Traditional Chinese medicinal spray of the control acute heart failure according to any one of claim 1-3, is characterized in that: specifically have following steps to be prepared from:
1. Os Draconis are smashed, be placed on smokeless stove fire, burn and make the carbonization of medical surfaces part to outside burned black for spending, then grind to form smalls, cross 60-100 mesh sieve stand-by;
2. be divided into two by Pheretima, clean, with the slightly vexed 10-20 minute of Chinese liquor, be placed in the hot pot that dryouies, repeatedly stir-fry to crisp, it is stand-by to grind to form smalls;
3. clear water is placed in marmite, Colla Corii Asini is added after big fire is boiled, the Rhizoma Arisaematis of clean chopping, Herba Centellae, Rhizoma Rhodiolae kirilowii, Herba Apocyni veneti, Ganoderma, Arillus Longan, the Radix Astragali, Radix Salviae Miltiorrhizae, Ramulus Cinnamomi and Radix Ophiopogonis is added after Colla Corii Asini melts completely, while stir infusion on one side with large ferrum spoon, add after filtrate is boiled step 1. with step 2. gained smalls, after intense fire is fried open, cover seal cover, turn slow fire boiling 60-90 minute, sealing and standing 3-5 hour, get supernatant stand-by;
4. Semen Juglandis is placed in and burns on hot clean iron plate, when Semen Juglandis is dried to crisp, grind to form smalls, cross 80-120 mesh sieve;
5. by step 3. gained supernatant add step 4. gained walnut powder after being heated to 80 DEG C, until boiling after 10 minutes, dry heat sterilization 3-8 minute at 120-140 DEG C, is sealed in after cooling in plastic bottle, obtains Traditional Chinese medicinal spray.
5. the preparation method of Traditional Chinese medicinal spray according to claim 4, is characterized in that: step 1. smalls crosses 70-90 mesh sieve stand-by (preferred, it is stand-by that smalls crosses 80 mesh sieves).
6. the preparation method of Traditional Chinese medicinal spray according to claim 4, it is characterized in that: the consumption of step 2. Chinese liquor is that the 1-3 of Pheretima weight is doubly (preferred, the consumption of Chinese liquor is 1.5-2.5 times of Pheretima weight, and be more preferably, the consumption of Chinese liquor is 2 times of Pheretima weight).
7. the preparation method of Traditional Chinese medicinal spray according to claim 4, is characterized in that: step is 2. with slightly vexed 13-18 minute of Chinese liquor (preferred, with Chinese liquor slightly vexed 15 minutes).
8. the preparation method of Traditional Chinese medicinal spray according to claim 4, is characterized in that: 3. step turns slow fire boiling 70-80 minute, sealing and standing 3.5-4.5 hour (preferred, to turn slow fire boiling 75 minutes, sealing and standing 4 hours).
9. the preparation method of Traditional Chinese medicinal spray according to claim 4, is characterized in that: step 5. at 125-135 DEG C dry heat sterilization 5-7 minute (preferred, dry heat sterilization 6 minutes at 130 DEG C).
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| CN105687869A (en) * | 2016-03-23 | 2016-06-22 | 贾德权 | Lozenges for relieving heart failure and preparation method thereof |
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| JP2003277279A (en) * | 2002-03-20 | 2003-10-02 | Fancl Corp | Endothelin antagonist |
| CN1628712A (en) * | 2003-12-18 | 2005-06-22 | 董亮 | Method for preparing heart tranquilizing oral liquor |
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