CN104547432A - Traditional Chinese medicine composition for treating hypertensive heart disease and preparation method of traditional Chinese medicine composition - Google Patents
Traditional Chinese medicine composition for treating hypertensive heart disease and preparation method of traditional Chinese medicine composition Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for treating hypertensive heart disease. The traditional Chinese medicine composition is prepared from the following main raw materials in parts by weight: 5-15 parts of honeysuckles, 10-20 parts of cirsium japonicum, 3-9 parts of astragalus, 0.2-0.8 part of alkali halide, 1-5 parts of dragon bones, 3-8 parts of Chinese yams, 1-5 parts of radix angelicae pubescentis, 5-15 parts of sweet wormwood herbs, 4-10 parts of agaric, 2-6 parts of lycopene, 1-5 parts of astaxanthin, 3-8 parts of radix puerariae, 2-6 parts of capsella bursa-pastoris, 8-15 parts of antelope horns, 1-3 parts of saliva miltiorrhiza and 7-12 parts of coptis chinensis. The traditional Chinese medicine composition is available in medicinal material source and low in cost, and most of the selected medicinal materials are mild in drug property, so that the economic and physical burdens of a user cannot be increased even if the traditional Chinese medicine composition is used for a long term.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of Chinese medicine composition and preparation method for the treatment of hypertensive heart disease.
Background technology
Hypertension long-term control is not good causes the change of cardiac function and structure to be called hypertensive heart disease, comprise: early stage Diastole Function goes down, left ventricular hypertrophy (LVH), progressively development occurs that myocardium shrinkage function goes down and finally heart failure occurs, and has the heart failure of research display 70% by caused by hypertension; Associated coronary heart disease may be there is, the heart complication such as atrial fibrillation simultaneously.
Pathophysiological change 1. left ventricular hypertrophy (LVH): LVH is that a kind of cardiac muscle changes the compensatory that blood pressure raises, myocardial contraction strengthens to maintain enough heart strokes, but time length can cause cardiac myocyte hypertrophy, muscle fiber increases thick, degeneration, under blood capillary relative density, degradation changes.There is Myocardial Remodeling phenomenon in early days, namely centration is reinvented, cardiac myocyte hypertrophy, but quantity does not increase, arrangement changes, and collagen fiber increase, progressively there is fibrosis more than 20% in Collagen accumulation, to replace the cell losing function, thus there is concentric hypertrophy, volume load increase finally occurs and causes eccentric hypertrophy.First hypertensive LVH is reflected in interventricular septum and thickens, and the latter is that cardiac size circulates common part, all has very important effect to left and right ventricles contractile function.2. diastolic function goes down: the feature of relaxing period heart failure is that bulk of left ventricle minimizing and end-diastolic voltage rise are high, and LVEF normally or slightly lowers.This is mainly normal due to ventricular systolic function, and ventricular muscles lusitropic and compliance attenuating make ventricular filling reduce; For increasing ventricular filling, left room must be improved filling pressure and obtain normal ventricular filling and stroke volume.LVH makes cardiac myocyte hypertrophy in addition, and especially myocardial fibrosis makes myocardial relaxation phase pressure-volume relation change, and also make diastolic pressure in the chambers of the heart raise, therefore LVH can cause diastolic function to go down.Hypertension early stage cardiac structure function changes, and diastolic function goes down and accounts for 11%.3. contractile function goes down: there will be a known LVH person than high 10 times without LVH person's heart failure, afterload is caused excessively to increase this is because chronic stress raises, cause vessel wall thickness and heart concentric hypertrophy and diastolic relaxation impaired, finally occur that myocardial contraction declines, the chambers of the heart expands, and VDV increases, and ventricular filling pressure and atrial pressure all increase,, there is the acute or chronic left-sided heart failure of hypertensive heart disease in pulmonary vein backflow obstruction.
Clinical manifestation: 1. early clinical manifestation: Early manifestation is not generally true to type, patient slight just as can not to have a headache without obvious subjective symptoms or only have, uncomfortable in chest etc., and these symptoms mainly hypertensive general symptom, without particularity.2. progressive stage clinical manifestation: due to arteries hypertonia during hypertension, hinders heart pump to go out blood, and the long-term high load capacity work of heart has just occurred that myocardial hypertrophy and stiffness index increase, and finally causes the pulmonary vein entering heart to be obstructed, forms pulmonary venous pleonaemia.During myocardial hypertrophy, oxygen demand increases, and blood supply relative deficiency, often causes heart failure to show effect.Diastolic heart failure is similar with the clinical manifestation of contractility heart failure, clinically not easily differentiates.The clinical characters of the heart failure caused by hypertension is as follows: (1), due to LV Diastolic/systolic dysfunction, can cause pulmonary venous pleonaemia, and main manifestations is 1. exertional dyspnea; Occur out of breath when 2. putting down sleeping, namely take a turn for the better after sitting up; 3. activity is little, but occurs dyspnea, and time serious, patient can wake up with a start in one's sleep; 4. there is orthopnea, cough time seriously, cough pink foam expectorant.(2) left heart failure often can involve right ventricular function decline, forms whole heart failure, and main manifestations is that 1. jugular vein obviously fills; 2. right Upper abdominal pain, and have hepatomegaly; , time serious, can hydrosarca be there is in 3. two lower limbs edema; 4. oliguria.
In the Chinese medicine of existing treatment hypertensive heart disease, Authorization Notice No. CN 103055126 B (application number 201310017155.1) patent document discloses a kind of preparation method for the treatment of the Chinese medicine composition of hypertensive heart disease, it is characterized in that, take off the raw material stating weight proportion: Radix Panacis Quinquefolii 1-5 part, Radix Astragali 25-35 part, Stigma Croci 1-5 part, Poria 15-35 part, Radix Trichosanthis 15-30 part, Semen Platycladi 5-12 part, Lignum Dalbergiae Odoriferae 1-5 part, Radix Ophiopogonis 5-15 part, Radix Paeoniae Alba 25-35 part, Spica Prunellae 8-15 part, natural Broneolum Syntheticum 0.3-0.9 part, Ramulus Uncariae Cum Uncis 9-15 part.
As can be seen here, Chinese medicine occupies very important status in treatment hypertensive heart disease, but in patent documentation, the Chinese medicine composition being specifically designed to treatment hypertensive heart disease is also fewer.
Summary of the invention
For the deficiencies in the prior art, an object of the present invention is the Chinese medicine composition providing treatment hypertensive heart disease, medical material medicine source of the present invention is easy to get, with low cost, selected medical material mostly be mild in medicine property and thing, the food materials of Chinese crude drug and nourishing combine the tablet be prepared into, and life-time service also can not increase the burden on economy and health to user.
Another object of the present invention is just to provide the preparation method of above-mentioned Chinese medicine composition.
Technical scheme of the present invention is:
The Chinese medicine composition for the treatment of hypertensive heart disease, takes off the primary raw material stating weight proportion and is prepared from: Flos Lonicerae 5-15 part, Radix Cirsii Japonici 10-20 part, Radix Astragali 3-9 part, salt alkali 0.2-0.8 part, Os Draconis 1-5 part, Rhizoma Dioscoreae 3-8 part, Radix Angelicae Pubescentis 1-5 part, Herba Artemisiae Annuae 5-15 part, Auricularia 4-10 part, lycopene 2-6 part, astaxanthin 1-5 part, Radix Puerariae 3-8 part, Herba Capsellae 2-6 part, Cornu Saigae Tataricae 8-15 part, Radix Salviae Miltiorrhizae 1-3 part, Rhizoma Coptidis 7-12 part.
The Chinese medicine composition for the treatment of hypertensive heart disease, preferred scheme is, takes off the primary raw material stating weight proportion and is prepared from: Flos Lonicerae 8-13 part, Radix Cirsii Japonici 13-18 part, Radix Astragali 5-7 part, salt alkali 0.4-0.6 part, Os Draconis 2-4 part, Rhizoma Dioscoreae 4-7 part, Radix Angelicae Pubescentis 2-4 part, Herba Artemisiae Annuae 8-13 part, Auricularia 6-8 part, lycopene 3-5 part, astaxanthin 2-4 part, Radix Puerariae 4-7 part, Herba Capsellae 3-5 part, Cornu Saigae Tataricae 10-13 part, Radix Salviae Miltiorrhizae 1.5-2.5 part, Rhizoma Coptidis 9-11 part.
The Chinese medicine composition for the treatment of hypertensive heart disease, more preferred scheme is, takes off the primary raw material stating weight proportion and is prepared from: Flos Lonicerae 10 parts, Radix Cirsii Japonici 15 parts, the Radix Astragali 6 parts, salt alkali 0.5 part, Os Draconis 3 parts, Rhizoma Dioscoreae 5.5 parts, Radix Angelicae Pubescentis 3 parts, Herba Artemisiae Annuae 10 parts, 7 parts, Auricularia, lycopene 4 parts, astaxanthin 3 parts, Radix Puerariae 5 parts, 4 parts, Herba Capsellae, Cornu Saigae Tataricae 11 parts, Radix Salviae Miltiorrhizae 2 parts, Rhizoma Coptidis 10 parts.
The preparation method of above-mentioned Chinese medicine composition, step is as follows:
(1) Os Draconis and Cornu Saigae Tataricae are broken into pieces and be together placed in container with salt alkali, on smokeless stove fire, forging is crisp, grinds to form smalls after cooling, and crosses 80-120 mesh sieve;
(2) wheat bran is crossed 120-160 mesh sieve, the wheat bran shone is dropped in the hot pot dryouied, fry until wheat bran and drop into Flos Lonicerae, Radix Cirsii Japonici, the Radix Astragali and Radix Angelicae Pubescentis to during 60-70 DEG C, to repeatedly to stir-fry in the process of parch and with slow fire, parch 5-10 minute, sieve removes wheat bran, and the Flos Lonicerae fried, Radix Cirsii Japonici, the Radix Astragali and Radix Angelicae Pubescentis are ground to form smalls;
(3) Rhizoma Dioscoreae is cut into the block of coin-size, Auricularia is cleaned, be cut into filament and Rhizoma Dioscoreae block mixes, be placed in the Herba Artemisiae Annuae silk adding after food steamer steams 20-40 minute and cut, again steam 5-15 minute, with rolling pin, the Rhizoma Dioscoreae block steamed is ground into thick paste, by thick paste and microwave oven, baking 2-5 minute, dries in the air cool stand-by;
(4) Radix Puerariae, Herba Capsellae, Radix Salviae Miltiorrhizae and Rhizoma Coptidis are decocted with water twice, water consumption is 2-4 times of Radix Puerariae, Herba Capsellae, Radix Salviae Miltiorrhizae and Rhizoma Coptidis gross weight for the first time, and big fire decocts to boiling, filters after 5 minutes until boiling, obtain filtrate 1, the filtering residue little fire that again adds water simmers 50-70 minute slowly, changes big fire and decocts 3-8 minute, filter, obtain filtrate 2, filtrate 1 and filtrate 2 are mixed, leaves standstill 2-6 hour, obtain supernatant;
(5) the little fire of step (4) gained supernatant is decocted slowly to boiling and add step (1)-(3) gained medicine; decoct while add lycopene and astaxanthin after being stirred to thawing completely with chopsticks; cease fire when abundant simmer down to thick paste; thick paste is placed on iron plate; little fire dries 8-14 minute slowly; obtain drying object, drying object is restrained standby one-tenth tablet according to every 0.1-0.3.
The preparation method of above-mentioned Chinese medicine composition, grinds to form smalls after step (1) cools, and crosses 90-110 mesh sieve (preferred, to grind to form smalls, cross 100 mesh sieves after cooling).
The preparation method of above-mentioned Chinese medicine composition, step (2) is fried until wheat bran and (preferably, is fried to input Flos Lonicerae, Radix Cirsii Japonici, the Radix Astragali and Radix Angelicae Pubescentis when 65 DEG C until wheat bran to dropping into Flos Lonicerae, Radix Cirsii Japonici, the Radix Astragali and Radix Angelicae Pubescentis during 63-68 DEG C.
The preparation method of above-mentioned Chinese medicine composition, will stir-fry in the process of step (2) parch and repeatedly with slow fire, parch 6-9 minute (preferred, to repeatedly to stir-fry in the process of parch and with slow fire, parch 8 minutes).
The preparation method of above-mentioned Chinese medicine composition, step (3) adds the Herba Artemisiae Annuae silk cut after being placed in and food steamer steaming 25-35 minute, again steam 8-13 minute (preferred, to be placed in the Herba Artemisiae Annuae silk adding after food steamer steams 30 minutes and cut, again to steam 10 minutes).
The preparation method of above-mentioned Chinese medicine composition, step (4) first time water consumption is the 2.5-3.5 of Radix Puerariae, Herba Capsellae, Radix Salviae Miltiorrhizae and Rhizoma Coptidis gross weight doubly (preferred, water consumption is 3 times of Radix Puerariae, Herba Capsellae, Radix Salviae Miltiorrhizae and Rhizoma Coptidis gross weight for the first time).
The preparation method of above-mentioned Chinese medicine composition, filtrate 1 and filtrate 2 mix by step (4), leave standstill 3-5 hour (preferred, filtrate 1 and filtrate 2 to be mixed, leave standstill 4 hours).
Best using method: be the therapeutic effect making the present invention reach best, the Chinese medicine composition made, took with half an hour after breakfast, lunch and dinner, each 1-3 sheet, warm water delivery service.
The pharmacological effect of each crude drug is respectively:
Flos Lonicerae: Flos Lonicerae is just extensive and famous with its medical value since ancient times.Its effect mainly heat-clearing and toxic substances removing, cures mainly epidemic febrile disease heating, toxic-heat and blood stasis, carbuncle furunculosis etc.Modern study proves, Flos Lonicerae contains the pharmacological component such as chlorogenic acid, luteolin glycosides, stronger restraint is had to the various pathogens such as Hemolytic streptococcus, staphylococcus aureus and upper respiratory tract infection Causative virus etc., in addition also can enhancing immunity, antiearly pregnancy, hepatoprotective, antitumor, antiinflammatory, antipyretic, hemostasis (blood coagulation), suppress intestinal absorption cholesterol etc., its clinical application widely, can be used for the treatment of respiratory tract infection, bacillary dysentery, acute urinary, hypertension etc. more than 40 with other medicines compatibility and plant disease.Flos Lonicerae is cold in nature, sweet in the mouth, enters lung, the heart, stomach warp, has heat-clearing and toxic substances removing, antiinflammatory, tonify deficiency treat effect of wind, cures mainly disease under distension, epidemic febrile disease heating, the diseases such as pyretic toxicity carbuncle and ulcer and tumor.The diseases such as it is dizzy for giddy, xerostomia is done yearningly, hyperhidrosis is unhappy, enteritis, bacillary dysentery, measles, pneumonia, encephalitis b, epidemic encephalitis, acute mastitis, septicemia, appendicitis, skin infection, carbuncle furuncle, erysipelas, parotitis, suppurative tonsillitis all have certain curative effect.
Radix Cirsii Japonici: having another name called horse Ji, wild thorn dish, thatch mustard, is aerial parts or the root of Compositae artichoke plant Radix Cirsii Japonici.The property of medicine: sweet in the mouth, slightly cool in nature.Composition: fresh leaf contains pectolinarin; Root contains volatile oil component aplotaxene, Rhizoma Cyperi alkene, Flos Caryophylli alkene.Find according to modern pharmacological research, this medical instrument has effect of hemostasis, blood pressure lowering, the detumescence of antibacterial, clots absorbing, and for spitting blood, spitting of blood, epistaxis, has blood in stool, hematuria, and skin infection swells and ache, nephritis, eczema etc.
The Radix Astragali: it has enhancing human body immunity function, protects the liver, diuresis, defying age, anti-stress, blood pressure lowering and antibacterial action more widely.But table excess pathogen is contained, retention of dampness due to stagnation of QI, and food stagnation is stagnated.
Salt alkali: base is former: for enriched bittern cake (solid salt) decocts through processing the white crystals body made.Composition: be mainly magnesium chloride; Secondly also containing sodium, potassium, calcium, sulfate radical, silicon dioxide, strontium, ferrum etc.Sea salt, lake salt, well salt and salt-soda soil salt four kinds of salt are different with the composition of salt alkali.The property of medicine: bitter, salty, cold.Function cures mainly: clearing away heat-fire, reduces phlegm, softening the hard mass, improving eyesight.Cure mainly large hot excessive thirst, the puckery pain of wind heat conjunctival congestion, Keshan disease, Kaschin-Beck disease, goiter, rheumatic heart disease, hypertension, chronic bronchitis.
Os Draconis: base is former: for mammal in ancient times resembles the Skeletal Fossils of class, rhinoceros class, Hippocampal cortex, bovine, deer class etc.Composition: Os Draconis, mainly containing calcium carbonate and calcium phosphate, still contain ferrum, potassium, sodium, chlorine, sulfate radical etc.The property of medicine: puckery, sweet, flat.GUIXIN, liver, kidney, large intestine channel.Function cures mainly: tranquilizing mind, suppressing the hyperactive liver and subsiding YANG, restrains astringent or styptic treatment for spontaneous sweating.Cure mainly cardiopalmus, seized with terror swollen, insomnia, forgetful, infantile convulsion, demented, dizzy, spontaneous sweating, the seminal emission enuresis, bleeding not during menses, chronic diarrhea and dysentery, ulcer does not close up and eczema for a long time.
Cornu Saigae Tataricae: base is former: for Bovidae Saigae Tataricae belongs to the angle of animal sahilite.Composition: sahilite angle contains keratin, calcium phosphate, insoluble inorganic salt, lysine, serine, glutamic acid, phenylalanine, leucine, aspartic acid etc.The property of medicine: salty, cold.Return liver, heart channel.Function cures mainly: suppressing the hyperactive liver to relieve the wind syndrome, liver heat removing and eyesight improving, blood-cleaning detoxifying.Cure mainly liver-wind stirring up internally, infantile convulsion is twitched, the contracture of muscle arteries and veins; Headache due to hyperactivity of liver-YANG is dizzy, liver-fire conjunctival congestion and swelling pain and heat in blood hemorrhage, epidemic febrile disease sends out speckle, carbuncle sore tumefacting virus.
Rhizoma Dioscoreae: have and nourish strong, aid digestion, hold back sweating due to debility, effect of antidiarrheal, cure mainly insufficiency of the spleen diarrhoea, cough due to deficiency of the lung, diabetes are quenched one's thirst, oliguria frequently, seminal emission, women's leukorrhagia and dyspeptic chronic enteritis.
Radix Angelicae Pubescentis: be the root of the heavy tooth Radix Angelicae Sinensis of Umbelliferae archangel.Composition: containing coumarin kind compound, volatile oil, acetas, angelol, thymol.Pharmacology: play a very important role to cardiovascular system, has the effect of blood pressure lowering, can promote hematoblastic gathering, have good analgesia and antiinflammatory action.There is anti-light quick effect, have significant curative effect to opposing tumor, anti-inflammation is also played a very important role.The property of medicine: bitter, tepor, pungent.Return kidney, urinary bladder channel.Function cures mainly: expelling wind and dampness, dispersing cold for relieving pain.
Herba Artemisiae Annuae: Herba Artemisiae Annuae decocting liquid has stronger bacteriostasis to staphylococcus epidermidis, micrococcus catarrhalis, anthrax bacillus, diphtheria corynebacterium, also has certain inhibitory action to staphylococcus aureus, bacillus pyocyaneus, dysentery bacterium, tuberculosis stalk bacterium etc.Herba Artemisiae Annuae volatile oil, when 0.25% concentration, has bacteriostasis to all dermatophytosises, when 1% concentration, has bactericidal action to all dermatophytosises.Herba Artemisiae Annuae have the effect of resisiting influenza virus.Sodium artesunate is to golden Fructus Vitis viniferae, shigella flexneri, escherichia coli, micrococcus catarrhalis, and A type and paratyphoid B stalk bacterium all have certain antibacterial action.Sitosterol in Herba Artemisiae Annuae and stigmasterol also have antivirus action.Arteannuin can decreased heart rate, suppresses myocardial contraction, reduces coronary flow.Intravenous injection has hypotensive activity, but does not affect the booster reaction of norepinephrine, thinks that main system changed the direct suppression of heart.
Auricularia: Auricularia, Chinese medicine name.For the sporophore of Mycophyta Auriculariaceae plant Auricularia Auricularia auricular (L.) Underw..The ground such as to be distributed in.There is benefiting qi and nourishing blood, lung moistening, hemostasis, blood pressure lowering, anticancer effect.Be usually used in Qi and blood deficiency, extremity are twitched, chronic cough of deficiency lung, spitting of blood, spit blood, epistaxis, dysentery, bleeding hemorrhoids, woman uterine bleeding, hypertension, constipation, retinal hemorrhage, sub-Cervical cancer, cancer of vagina, traumatic injury.
Lycopene: protection cardiovascular: in atherosclerotic generation and evolution, the lipoprotein oxidation in tunica intima is a key factor.Lycopene plays an important role in reduction lipoprotein oxidation.It is reported that oral natural lycopene can make serum cholesterol be down to less than 5.20 mM/ls, lycopene, for preventing and treating hypercholesterolemia and hyperlipidemia, can slow down the development of cardiovascular disease.
Astaxanthin: have another name called astaxanthin, Astaxanthin, be a Carotenoids, pinkiness, is extensively present in biosphere, in the feather of particularly shrimp, Eriocheir sinensis, fish, frond, yeast and birds, content is higher, is one of carotenoid main in marine organism.Chemical name is 3,3 '-dihydroxy-4,4 '-diketo beta-carotene, in vivo can with protein bound and in blue or green, blue.To human body, there is comprehensive antioxidation benefit, comprising: defying age, antitumor, prevention cardiovascular and cerebrovascular disease, the Maintenance Of Skin Health, improve the effects such as motion function.
Radix Puerariae: be the dry root of legume pueraria lobata, practises and claims Herba Gelsemii Elegantis.Autumn, season in winter two excavate, and take advantage of fresh-cut and become sheet or fritter; Dry.Sweet, pungent, cool.There is expelling pathogenic factors from muscles for reducing heat, rash, promoting the production of body fluid to quench thirst, the merit of yang invigorating antidiarrheal.Be usually used in exterior syndrome heating, stiff nape and back, measles without adequate eruption, calentura is thirsty, and the deficiency of YIN is quenched one's thirst, diarrhea of heat type hematodiarrhoea, diarrhea due to hypofunction of the spleen.
Herba Capsellae: base is former: be the herb of Cruciferae shepherd's purse platymiscium Herba Capsellae.Composition: herb is containing flavonoid: dihydrofisetin, Quercetin-3-methyl ether, gossypetin pregnancy ether diosmin, 3,4 ', 7-trihydroxy flavane copper etc.
Fatty acid: Palmic acid, Fumaric acid, oxalic acid, tartaric acid, malic acid etc.Alkaloids: choline, acetylcholine, sinapic acid choline ester. etc.The property of medicine: sweet, light, cool.Return liver, spleen, urinary bladder channel.Function cures mainly: cool liver hemostasis, suppressing the hyperactive liver improving eyesight, clearing away heat-damp and promoting diuresis.Cure mainly haematemesis, epistaxis, spitting of blood, hematuria, metrorrhagia, conjunctival congestion and pain of eye, retinal hemorrhage, hypertension, dysentery, oedema due to nephritis, chyluria.
Radix Salviae Miltiorrhizae: have blood circulation promoting and blood stasis dispelling, inducing menstruation to relieve menalgia, clear away heart-fire relieving restlessness, effect of removing heat from blood eliminating carbuncle.For obstruction of qi in the chest and cardialgia, gastral cavity abdomen hypochondriac pain, abdominal mass abdominal mass is gathered, pyretic arthralgia pain, dysphoria and insomnia, menoxenia, and dysmenorrhea amenorrhea, skin infection swells and ache.
Rhizoma Coptidis: GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel, damp and hot feeling of fullness, vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, palpitation and uneasiness, heat in blood tells nosebleed, conjunctival congestion, and toothache, quenches one's thirst, and carbuncle treats skin ulcer; External treatment eczema, eczema, auditory meatus is suppurated.
1, Chinese medicine composition of the present invention " more holistic ", both hypertensive heart disease can be treated, again can blood pressure lowering, most importantly the food materials of Chinese crude drug and nourishing are combined, this is the large feature being different from Drug therapy, and this Chinese medicine composition is prepared from according to Chinese medicine principle completely, more safe and reliable, without any side effects, to matrix without any stimulation.
2, Chinese medicine composition of the present invention meets the principle of Chinese traditional treatment hypertensive heart disease.The medical material selected has efficacy in lowering high blood pressure, and strongly fragrant depressed, the pain relieving of the heart of releiving, arresting convulsion of calming the nerves, fabulous therapeutical effect is had to hypertensive heart disease patient, be treat the ideal medicine of hypertensive heart disease at present, and have unique curative effect to diseases such as coronary artery medicated porridge sample heart disease and angina pectoriss.
3, selected by Chinese medicine preparation of the present invention, medical material compatibility is suitable, and adopt modern advanced pharmaceutical technology to make, evident in efficacy, safe without toxic side effect, treating both the principal and secondary aspects of a disease, should be widely promoted application.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
Embodiment 1 treats the Chinese medicine composition of hypertensive heart disease, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Flos Lonicerae 5 parts, Radix Cirsii Japonici 10 parts, the Radix Astragali 3 parts, salt alkali 0.2 part, Os Draconis 1 part, Rhizoma Dioscoreae 3 parts, Radix Angelicae Pubescentis 1 part, Herba Artemisiae Annuae 5 parts, 4 parts, Auricularia, lycopene 2 parts, astaxanthin 1 part, Radix Puerariae 3 parts, 2 parts, Herba Capsellae, Cornu Saigae Tataricae 8 parts, Radix Salviae Miltiorrhizae 1 part, Rhizoma Coptidis 7 parts.
The preparation method of above-mentioned Chinese medicine composition, step is as follows:
(1) Os Draconis and Cornu Saigae Tataricae are broken into pieces and be together placed in container with salt alkali, on smokeless stove fire, forging is crisp, grinds to form smalls after cooling, and crosses 80 mesh sieves;
(2) wheat bran is crossed 120 mesh sieves, the wheat bran shone is dropped in the hot pot dryouied, fry until wheat bran and drop into Flos Lonicerae, Radix Cirsii Japonici, the Radix Astragali and Radix Angelicae Pubescentis to when 60 DEG C, to repeatedly to stir-fry in the process of parch and with slow fire, parch 5 minutes, sieve removes wheat bran, and the Flos Lonicerae fried, Radix Cirsii Japonici, the Radix Astragali and Radix Angelicae Pubescentis are ground to form smalls;
(3) Rhizoma Dioscoreae is cut into the block of coin-size, Auricularia is cleaned, be cut into filament and Rhizoma Dioscoreae block mixes, be placed in the Herba Artemisiae Annuae silk adding after food steamer steams 20 minutes and cut, again steam 5 minutes, with rolling pin, the Rhizoma Dioscoreae block steamed is ground into thick paste, by thick paste and microwave oven, toast 2 minutes, dry in the air cool stand-by;
(4) Radix Puerariae, Herba Capsellae, Radix Salviae Miltiorrhizae and Rhizoma Coptidis are decocted with water twice, water consumption is 2 times of Radix Puerariae, Herba Capsellae, Radix Salviae Miltiorrhizae and Rhizoma Coptidis gross weight for the first time, and big fire decocts to boiling, filters after 5 minutes until boiling, obtain filtrate 1, the filtering residue little fire that again adds water simmers 50 minutes slowly, changes big fire and decocts 3 minutes, filters, obtain filtrate 2, filtrate 1 and filtrate 2 are mixed, leaves standstill 2 hours, obtain supernatant;
(5) the little fire of step (4) gained supernatant is decocted slowly to boiling and add step (1)-(3) gained medicine; decoct while add lycopene and astaxanthin after being stirred to thawing completely with chopsticks; cease fire when abundant simmer down to thick paste; thick paste is placed on iron plate; little fire dries 8 minutes slowly; obtain drying object, drying object is restrained standby one-tenth tablet according to every 0.1.
Model case one: Wu XX, man, 63 years old, be people from Jinan: patient suffers from hypertension all the year round, before 2 months, occurred dyspneic symptom, for several times oneself is suppressed awake in bed, nervous, sometimes sensation is breathless, is hypertensive heart disease through hospital diagnosis, and doctor advised uses gained of the present invention to treat the Chinese medicine composition of hypertensive heart disease.
Use the present embodiment 1 gained Chinese medicine composition, take 4 days, obviously sensation is breathed smooth and easy, without sensation uncomfortable in chest; Use 15 days, only occur 2 dyspnea symptoms night period; Continue use 10 days, breathe smooth and easy, do not occur the phenomenon of breathing suffering night again; Consolidate 10 days, so far, dyspnea symptom does not occur again in drug withdrawal.
Embodiment 2 treats the Chinese medicine composition of hypertensive heart disease, takes off the primary raw material stating weight proportion and is prepared from (getting 5g for every part): Flos Lonicerae 15 parts, Radix Cirsii Japonici 20 parts, the Radix Astragali 9 parts, salt alkali 0.8 part, Os Draconis 5 parts, Rhizoma Dioscoreae 8 parts, Radix Angelicae Pubescentis 5 parts, Herba Artemisiae Annuae 15 parts, 10 parts, Auricularia, lycopene 6 parts, astaxanthin 5 parts, Radix Puerariae 8 parts, 6 parts, Herba Capsellae, Cornu Saigae Tataricae 15 parts, Radix Salviae Miltiorrhizae 3 parts, Rhizoma Coptidis 12 parts.
The preparation method of above-mentioned Chinese medicine composition, step is as follows:
(1) Os Draconis and Cornu Saigae Tataricae are broken into pieces and be together placed in container with salt alkali, on smokeless stove fire, forging is crisp, grinds to form smalls after cooling, and crosses 120 mesh sieves;
(2) wheat bran is crossed 160 mesh sieves, the wheat bran shone is dropped in the hot pot dryouied, fry until wheat bran and drop into Flos Lonicerae, Radix Cirsii Japonici, the Radix Astragali and Radix Angelicae Pubescentis to when 70 DEG C, to repeatedly to stir-fry in the process of parch and with slow fire, parch 10 minutes, sieve removes wheat bran, and the Flos Lonicerae fried, Radix Cirsii Japonici, the Radix Astragali and Radix Angelicae Pubescentis are ground to form smalls;
(3) Rhizoma Dioscoreae is cut into the block of coin-size, Auricularia is cleaned, be cut into filament and Rhizoma Dioscoreae block mixes, be placed in the Herba Artemisiae Annuae silk adding after food steamer steams 20-40 minute and cut, again steam 15 minutes, with rolling pin, the Rhizoma Dioscoreae block steamed is ground into thick paste, by thick paste and microwave oven, toast 5 minutes, dry in the air cool stand-by;
(4) Radix Puerariae, Herba Capsellae, Radix Salviae Miltiorrhizae and Rhizoma Coptidis are decocted with water twice, water consumption is 4 times of Radix Puerariae, Herba Capsellae, Radix Salviae Miltiorrhizae and Rhizoma Coptidis gross weight for the first time, and big fire decocts to boiling, filters after 5 minutes until boiling, obtain filtrate 1, the filtering residue little fire that again adds water simmers 70 minutes slowly, changes big fire and decocts 8 minutes, filters, obtain filtrate 2, filtrate 1 and filtrate 2 are mixed, leaves standstill 6 hours, obtain supernatant;
(5) the little fire of step (4) gained supernatant is decocted slowly to boiling and add step (1)-(3) gained medicine; decoct while add lycopene and astaxanthin after being stirred to thawing completely with chopsticks; cease fire when abundant simmer down to thick paste; thick paste is placed on iron plate; little fire dries 14 minutes slowly; obtain drying object, drying object is restrained standby one-tenth tablet according to every 0.3.
Embodiment 3 treats the Chinese medicine composition of hypertensive heart disease, takes off the primary raw material stating weight proportion and is prepared from (getting 15g for every part): Flos Lonicerae 8 parts, Radix Cirsii Japonici 13 parts, the Radix Astragali 5 parts, salt alkali 0.4 part, Os Draconis 2 parts, Rhizoma Dioscoreae 4 parts, Radix Angelicae Pubescentis 2 parts, Herba Artemisiae Annuae 8 parts, 6 parts, Auricularia, lycopene 3 parts, astaxanthin 2 parts, Radix Puerariae 4 parts, 3 parts, Herba Capsellae, Cornu Saigae Tataricae 10 parts, Radix Salviae Miltiorrhizae 1.5 parts, Rhizoma Coptidis 9 parts.
State the preparation method of Chinese medicine composition, step is as follows:
(1) Os Draconis and Cornu Saigae Tataricae are broken into pieces and be together placed in container with salt alkali, on smokeless stove fire, forging is crisp, grinds to form smalls after cooling, and crosses 90 mesh sieves;
(2) wheat bran is crossed 130 mesh sieves, the wheat bran shone is dropped in the hot pot dryouied, fry until wheat bran and drop into Flos Lonicerae, Radix Cirsii Japonici, the Radix Astragali and Radix Angelicae Pubescentis to when 63 DEG C, to repeatedly to stir-fry in the process of parch and with slow fire, parch 6 minutes, sieve removes wheat bran, and the Flos Lonicerae fried, Radix Cirsii Japonici, the Radix Astragali and Radix Angelicae Pubescentis are ground to form smalls;
(3) Rhizoma Dioscoreae is cut into the block of coin-size, Auricularia is cleaned, be cut into filament and Rhizoma Dioscoreae block mixes, be placed in the Herba Artemisiae Annuae silk adding after food steamer steams 25 minutes and cut, again steam 8 minutes, with rolling pin, the Rhizoma Dioscoreae block steamed is ground into thick paste, by thick paste and microwave oven, toast 3 minutes, dry in the air cool stand-by;
(4) Radix Puerariae, Herba Capsellae, Radix Salviae Miltiorrhizae and Rhizoma Coptidis are decocted with water twice, water consumption is 2.5 times of Radix Puerariae, Herba Capsellae, Radix Salviae Miltiorrhizae and Rhizoma Coptidis gross weight for the first time, and big fire decocts to boiling, filters after 5 minutes until boiling, obtain filtrate 1, the filtering residue little fire that again adds water simmers 55 minutes slowly, changes big fire and decocts 4 minutes, filters, obtain filtrate 2, filtrate 1 and filtrate 2 are mixed, leaves standstill 3 hours, obtain supernatant;
(5) the little fire of step (4) gained supernatant is decocted slowly to boiling and add step (1)-(3) gained medicine; decoct while add lycopene and astaxanthin after being stirred to thawing completely with chopsticks; cease fire when abundant simmer down to thick paste; thick paste is placed on iron plate; little fire dries 10 minutes slowly; obtain drying object, drying object is restrained standby one-tenth tablet according to every 0.15.
Model case two: pungent XX, female, 48 years old.Jinan, Shandong Province personage, start before patient's first quarter moon to occur spitting of blood, cardio palmus shape, occur symptom out of breath when putting down sleeping, after sitting up, namely symptom takes a turn for the better to some extent, understands through hospital, patient suffers from hypertension, diagnose it to be hypertensive heart disease, patient thinks expectant treatment, so doctor advised uses gained of the present invention to treat the Chinese medicine composition of hypertensive heart disease.
Use the present embodiment 3 gained Chinese medicine composition, take 2 days, cardiopalmus symptom alleviates; Use 5 days, spitting of blood number of times reduces, and cardiopalmus disappears, and flat sleeping seasonal epidemic pathogens emergency case shape takes a turn for the better to some extent; Use 10 days, spitting of blood transference cure, flat sleeping seasonal epidemic pathogens emergency case shape also disappears; Consolidate 10 days, malaise symptoms does not occur again, has no side effect between the operating period.
Embodiment 4 treats the Chinese medicine composition of hypertensive heart disease, takes off the primary raw material stating weight proportion and is prepared from (getting 20g for every part): Flos Lonicerae 13 parts, Radix Cirsii Japonici 18 parts, the Radix Astragali 7 parts, salt alkali 0.6 part, Os Draconis 4 parts, Rhizoma Dioscoreae 7 parts, Radix Angelicae Pubescentis 4 parts, Herba Artemisiae Annuae 13 parts, 8 parts, Auricularia, lycopene 5 parts, astaxanthin 4 parts, Radix Puerariae 7 parts, 5 parts, Herba Capsellae, Cornu Saigae Tataricae 13 parts, Radix Salviae Miltiorrhizae 2.5 parts, Rhizoma Coptidis 11 parts.
The preparation method of above-mentioned Chinese medicine composition, step is as follows:
(1) Os Draconis and Cornu Saigae Tataricae are broken into pieces and be together placed in container with salt alkali, on smokeless stove fire, forging is crisp, grinds to form smalls after cooling, and crosses 110 mesh sieves;
(2) wheat bran is crossed 150 mesh sieves, the wheat bran shone is dropped in the hot pot dryouied, fry until wheat bran and drop into Flos Lonicerae, Radix Cirsii Japonici, the Radix Astragali and Radix Angelicae Pubescentis to when 68 DEG C, to repeatedly to stir-fry in the process of parch and with slow fire, parch 9 minutes, sieve removes wheat bran, and the Flos Lonicerae fried, Radix Cirsii Japonici, the Radix Astragali and Radix Angelicae Pubescentis are ground to form smalls;
(3) Rhizoma Dioscoreae is cut into the block of coin-size, Auricularia is cleaned, be cut into filament and Rhizoma Dioscoreae block mixes, be placed in the Herba Artemisiae Annuae silk adding after food steamer steams 35 minutes and cut, again steam 13 minutes, with rolling pin, the Rhizoma Dioscoreae block steamed is ground into thick paste, by thick paste and microwave oven, toast 4 minutes, dry in the air cool stand-by;
(4) Radix Puerariae, Herba Capsellae, Radix Salviae Miltiorrhizae and Rhizoma Coptidis are decocted with water twice, water consumption is 3.5 times of Radix Puerariae, Herba Capsellae, Radix Salviae Miltiorrhizae and Rhizoma Coptidis gross weight for the first time, and big fire decocts to boiling, filters after 5 minutes until boiling, obtain filtrate 1, the filtering residue little fire that again adds water simmers 65 minutes slowly, changes big fire and decocts 7 minutes, filters, obtain filtrate 2, filtrate 1 and filtrate 2 are mixed, leaves standstill 5 hours, obtain supernatant;
(5) the little fire of step (4) gained supernatant is decocted slowly to boiling and add step (1)-(3) gained medicine; decoct while add lycopene and astaxanthin after being stirred to thawing completely with chopsticks; cease fire when abundant simmer down to thick paste; thick paste is placed on iron plate; little fire dries 12 minutes slowly; obtain drying object, drying object is restrained standby one-tenth tablet according to every 0.25.
Embodiment 5 treats the Chinese medicine composition of hypertensive heart disease, takes off the primary raw material stating weight proportion and is prepared from (getting 30g for every part): Flos Lonicerae 10 parts, Radix Cirsii Japonici 15 parts, the Radix Astragali 6 parts, salt alkali 0.5 part, Os Draconis 3 parts, Rhizoma Dioscoreae 5.5 parts, Radix Angelicae Pubescentis 3 parts, Herba Artemisiae Annuae 10 parts, 7 parts, Auricularia, lycopene 4 parts, astaxanthin 3 parts, Radix Puerariae 5 parts, 4 parts, Herba Capsellae, Cornu Saigae Tataricae 11 parts, Radix Salviae Miltiorrhizae 2 parts, Rhizoma Coptidis 10 parts.
The preparation method of above-mentioned Chinese medicine composition, step is as follows:
(1) Os Draconis and Cornu Saigae Tataricae are broken into pieces and be together placed in container with salt alkali, on smokeless stove fire, forging is crisp, grinds to form smalls after cooling, and crosses 100 mesh sieves;
(2) wheat bran is crossed 140 mesh sieves, the wheat bran shone is dropped in the hot pot dryouied, fry until wheat bran and drop into Flos Lonicerae, Radix Cirsii Japonici, the Radix Astragali and Radix Angelicae Pubescentis to when 65 DEG C, to repeatedly to stir-fry in the process of parch and with slow fire, parch 7 minutes, sieve removes wheat bran, and the Flos Lonicerae fried, Radix Cirsii Japonici, the Radix Astragali and Radix Angelicae Pubescentis are ground to form smalls;
(3) Rhizoma Dioscoreae is cut into the block of coin-size, Auricularia is cleaned, be cut into filament and Rhizoma Dioscoreae block mixes, be placed in the Herba Artemisiae Annuae silk adding after food steamer steams 30 minutes and cut, again steam 10 minutes, with rolling pin, the Rhizoma Dioscoreae block steamed is ground into thick paste, by thick paste and microwave oven, toast 3 minutes, dry in the air cool stand-by;
(4) Radix Puerariae, Herba Capsellae, Radix Salviae Miltiorrhizae and Rhizoma Coptidis are decocted with water twice, water consumption is 3 times of Radix Puerariae, Herba Capsellae, Radix Salviae Miltiorrhizae and Rhizoma Coptidis gross weight for the first time, and big fire decocts to boiling, filters after 5 minutes until boiling, obtain filtrate 1, the filtering residue little fire that again adds water simmers 60 minutes slowly, changes big fire and decocts 6 minutes, filters, obtain filtrate 2, filtrate 1 and filtrate 2 are mixed, leaves standstill 4 hours, obtain supernatant;
(5) the little fire of step (4) gained supernatant is decocted slowly to boiling and add step (1)-(3) gained medicine; decoct while add lycopene and astaxanthin after being stirred to thawing completely with chopsticks; cease fire when abundant simmer down to thick paste; thick paste is placed on iron plate; little fire dries 11 minutes slowly; obtain drying object, drying object is restrained standby one-tenth tablet according to every 0.2.
The clinical practice of the Chinese medicine composition of test example 1 embodiment 5 gained treatment hypertensive heart disease: we have randomly drawed 400 patients and have tested (400 hypertensive heart disease patients), be divided into experimental group and matched group, wherein women 200 example, male 200 example.Before test 1 week, Continuous Observation is carried out to this crowd, record symptom and change, be divided into two groups at random, experimental group and matched group, experimental group uses embodiment 5 products obtained therefrom, and matched group takes the medicine medicine of conventional therapy hypertensive heart disease (as fixed in irbesartan, ripple clothing etc.) of other treatment hypertensive heart disease.
Efficacy evaluation: cure: malaise symptoms disappears, effectively: malaise symptoms improves, invalid: malaise symptoms all disappears.
Observe 30 days time limits, observed once every 10 days, record and add up the improvement situation of all patients symptomatic.
Experimental result:
Experimental group: cure 190 examples (95%) in 200 routine patients, effective 6 examples (3%), invalid 4 examples (2%), total effective rate 98%, within the observation period, all patients react without any discomfort.
Matched group: effective 130 examples (65%) in 200 routine patients, effective 50 examples (25%), invalid 20 examples (10%), total effective rate 90%, within the observation period, having 20 examples (10%) patient to occur, uncomfortable in chest increasing the weight of waits untoward reaction, and the malaise symptoms such as vomiting appear in 40 examples (20%) patient.
Claims (10)
1. treat the Chinese medicine composition of hypertensive heart disease, it is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Flos Lonicerae 5-15 part, Radix Cirsii Japonici 10-20 part, Radix Astragali 3-9 part, salt alkali 0.2-0.8 part, Os Draconis 1-5 part, Rhizoma Dioscoreae 3-8 part, Radix Angelicae Pubescentis 1-5 part, Herba Artemisiae Annuae 5-15 part, Auricularia 4-10 part, lycopene 2-6 part, astaxanthin 1-5 part, Radix Puerariae 3-8 part, Herba Capsellae 2-6 part, Cornu Saigae Tataricae 8-15 part, Radix Salviae Miltiorrhizae 1-3 part, Rhizoma Coptidis 7-12 part.
2. the Chinese medicine composition for the treatment of hypertensive heart disease according to claim 1, is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Flos Lonicerae 8-13 part, Radix Cirsii Japonici 13-18 part, Radix Astragali 5-7 part, salt alkali 0.4-0.6 part, Os Draconis 2-4 part, Rhizoma Dioscoreae 4-7 part, Radix Angelicae Pubescentis 2-4 part, Herba Artemisiae Annuae 8-13 part, Auricularia 6-8 part, lycopene 3-5 part, astaxanthin 2-4 part, Radix Puerariae 4-7 part, Herba Capsellae 3-5 part, Cornu Saigae Tataricae 10-13 part, Radix Salviae Miltiorrhizae 1.5-2.5 part, Rhizoma Coptidis 9-11 part.
3. the Chinese medicine composition for the treatment of hypertensive heart disease according to claim 1, is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Flos Lonicerae 10 parts, Radix Cirsii Japonici 15 parts, the Radix Astragali 6 parts, salt alkali 0.5 part, Os Draconis 3 parts, Rhizoma Dioscoreae 5.5 parts, Radix Angelicae Pubescentis 3 parts, Herba Artemisiae Annuae 10 parts, 7 parts, Auricularia, lycopene 4 parts, astaxanthin 3 parts, Radix Puerariae 5 parts, 4 parts, Herba Capsellae, Cornu Saigae Tataricae 11 parts, Radix Salviae Miltiorrhizae 2 parts, Rhizoma Coptidis 10 parts.
4. the preparation method of the Chinese medicine composition according to any one of claim 1-3, is characterized in that: step is as follows:
(1) Os Draconis and Cornu Saigae Tataricae are broken into pieces and be together placed in container with salt alkali, on smokeless stove fire, forging is crisp, grinds to form smalls after cooling, and crosses 80-120 mesh sieve;
(2) wheat bran is crossed 120-160 mesh sieve, the wheat bran shone is dropped in the hot pot dryouied, fry until wheat bran and drop into Flos Lonicerae, Radix Cirsii Japonici, the Radix Astragali and Radix Angelicae Pubescentis to during 60-70 DEG C, to repeatedly to stir-fry in the process of parch and with slow fire, parch 5-10 minute, sieve removes wheat bran, and the Flos Lonicerae fried, Radix Cirsii Japonici, the Radix Astragali and Radix Angelicae Pubescentis are ground to form smalls;
(3) Rhizoma Dioscoreae is cut into the block of coin-size, Auricularia is cleaned, be cut into filament and Rhizoma Dioscoreae block mixes, be placed in the Herba Artemisiae Annuae silk adding after food steamer steams 20-40 minute and cut, again steam 5-15 minute, with rolling pin, the Rhizoma Dioscoreae block steamed is ground into thick paste, by thick paste and microwave oven, baking 2-5 minute, dries in the air cool stand-by;
(4) Radix Puerariae, Herba Capsellae, Radix Salviae Miltiorrhizae and Rhizoma Coptidis are decocted with water twice, water consumption is 2-4 times of Radix Puerariae, Herba Capsellae, Radix Salviae Miltiorrhizae and Rhizoma Coptidis gross weight for the first time, and big fire decocts to boiling, filters after 5 minutes until boiling, obtain filtrate 1, the filtering residue little fire that again adds water simmers 50-70 minute slowly, changes big fire and decocts 3-8 minute, filter, obtain filtrate 2, filtrate 1 and filtrate 2 are mixed, leaves standstill 2-6 hour, obtain supernatant;
(5) the little fire of step (4) gained supernatant is decocted slowly to boiling and add step (1)-(3) gained medicine; decoct while add lycopene and astaxanthin after being stirred to thawing completely with chopsticks; cease fire when abundant simmer down to thick paste; thick paste is placed on iron plate; little fire dries 8-14 minute slowly; obtain drying object, drying object is restrained standby one-tenth tablet according to every 0.1-0.3.
5. the preparation method of Chinese medicine composition according to claim 4, is characterized in that: grind to form smalls after step (1) cools, and crosses 90-110 mesh sieve (preferred, to grind to form smalls, cross 100 mesh sieves after cooling).
6. the preparation method of Chinese medicine composition according to claim 4, it is characterized in that: step (2) is fried until wheat bran and (preferably, fried to input Flos Lonicerae, Radix Cirsii Japonici, the Radix Astragali and Radix Angelicae Pubescentis when 65 DEG C until wheat bran to dropping into Flos Lonicerae, Radix Cirsii Japonici, the Radix Astragali and Radix Angelicae Pubescentis during 63-68 DEG C.
7. the preparation method of Chinese medicine composition according to claim 4, it is characterized in that: will repeatedly to stir-fry in the process of step (2) parch and with slow fire, parch 6-9 minute (preferred, to repeatedly to stir-fry in the process of parch and with slow fire, parch 8 minutes).
8. the preparation method of Chinese medicine composition according to claim 4, it is characterized in that: step (3) adds the Herba Artemisiae Annuae silk cut after being placed in and food steamer steaming 25-35 minute, it is (preferred again to steam 8-13 minute, be placed in the Herba Artemisiae Annuae silk adding after food steamer steams 30 minutes and cut, again steam 10 minutes).
9. the preparation method of Chinese medicine composition according to claim 4, it is characterized in that: step (4) first time water consumption is the 2.5-3.5 of Radix Puerariae, Herba Capsellae, Radix Salviae Miltiorrhizae and Rhizoma Coptidis gross weight doubly (preferred, water consumption is 3 times of Radix Puerariae, Herba Capsellae, Radix Salviae Miltiorrhizae and Rhizoma Coptidis gross weight for the first time).
10. the preparation method of Chinese medicine composition according to claim 4, is characterized in that: filtrate 1 and filtrate 2 mix by step (4), leaves standstill 3-5 hour (preferred, filtrate 1 and filtrate 2 to be mixed, leave standstill 4 hours).
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