CN104740268A - Traditional Chinese medicinal composition for treating coronary heart disease - Google Patents
Traditional Chinese medicinal composition for treating coronary heart disease Download PDFInfo
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Abstract
The invention relates to a medicine for treating coronary heart disease, and especially relates to a traditional Chinese medicinal composition for treating coronary heart disease and prepared from plants and Chinese herbal medicines. The composition comprises, by weight, 10-20 parts of Salvia miltiorrhiza, 10-25 parts of Radix Puerariae, 5-10 parts of ginseng, 10-15 parts of Fructus Aurantii, 5-10 parts of licorice root, 10-15 parts of Radix Ophiopogonis, 15-20 parts of Chinese angelica, 20-30 parts of Radix Astragali, 10-15 parts of Ligusticum wallichii, 5-10 parts of Panax Notoginseng, 10-15 parts of Acorus gramineus, 5-15 parts of corydalis tuber, 10-15 parts of Radix Aucklandiae, 5-10 parts of peach seed, 10-20 parts of radix paeoniae rubra, 10-15 parts of safflower, 5-10 parts of snakegourd fruit, 5-10 parts of Radix Polygalae, 5-15 parts of Gambir Plant, 1-5 parts of evening primrose of safflower, 1-5 parts of Dracocephalum moldavica L. and 15-25 parts of white peony root. Above medicines are combined and complement each other, so the composition has body nourishing, mind tranquilizing, blood circulation invigorating, stasis transforming, qi moving, pain relieving and energy invigorating effects, has small side effects, and can alleviate and treat the coronary heart disease.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of coronary heart disease, particularly relating to a kind of take vegetable Chinese herbal medicine as the Chinese medicine composition of the treatment coronary heart disease that raw material is made.
Background technology
Coronary heart disease, referred to as coronary heart disease, refers to because lipid metabolism is abnormal, and the lipid in blood is calm on the endarterium of otherwise smooth, piles up and forms white speckle, be called atherosclerotic lesion at the lipid material of some similar medicated porridge samples of endarterium.These specklees increase gradually and cause stricture of artery, blood flow is obstructed, causes heart ischemia, produce angina pectoris.To feel oppressed pain with pareordia, even the position such as inside the thorough shoulder back of the body of pain, throat, left upper arm, in ictal or be in a sustained way main clinical characteristics.The sharp ache person of not understanding, often accompanies cold extremities due to sweating, pale complexion, cyanosis of the lips and nails, or shortness of breath and palpitation.Failing to sleep due to dyspnea, even dies suddenly.Middle-aged and elderly people is the principal pathogenetic crowd of coronary heart disease, and the situations such as the born of the same parents that catch cold food, the too drastic and strenuous exercise of emotion are often the inducement of ACA.
The Therapeutic Method of current coronary heart disease, there is physiotherapy, laser therapy, medicine is based on Western medicine substantially, many employings expansion class medicine (such as nitroglycerin, sorbitrate etc.), statins antilipemic medicine (such as lipitor, lovastatin) or anti-platelet agent (as aspirin) etc., although the effective mitigate the disease of Western medicine energy, thoroughly can not suppress the recurrence of the state of an illness, and the side effect of Western medicine own is large, long-term taking can produce untoward reaction to health.The method for the treatment of coronary disease with traditional Chinese medicine is also a lot, but effect is also not quite similar, so in order to more effectively treat coronary heart disease disease, spy preferably adopts more effective herbal treatment further.
Summary of the invention
The object of the invention is exactly that provide the Chinese medicine composition of the effective treatment coronary heart disease of a kind of activity, side effect is little, economical and practical, evident in efficacy, can Self-operating in order to more effectively treat coronary heart disease.
Its technical scheme is, comprises the raw material composition of following weight portion: Radix Salviae Miltiorrhizae 10-20 part, Radix Puerariae 10-25 part, Radix Ginseng 5-10 part, Fructus Aurantii 10-15 part, Radix Glycyrrhizae 5-10 part, Radix Ophiopogonis 10-15 part, Radix Angelicae Sinensis 15-20 part, Radix Astragali 20-30 part, Rhizoma Chuanxiong 10-15 part, Radix Notoginseng 5-10 part, Rhizoma Acori Graminei 10-15 part, Rhizoma Corydalis 5-15 part, Radix Aucklandiae 10-15 part, Semen Persicae 5-10 part, Radix Paeoniae Rubra 10-20 part, Flos Carthami 10-15 part, Fructus Trichosanthis 5-10 part, Radix Polygalae 5-10 part, Ramulus Uncariae Cum Uncis 5-15 part, oenothera rosea L' Her. Ex Aif 1-5 part, Herba Dracocephali 1-5 part, Radix Paeoniae Alba 15-25 part.
Drug action mechanism of the present invention and constituent component analysis are
Radix Salviae Miltiorrhizae: blood circulation promoting and blood stasis dispelling, calming heart and tranquilizing mind, evacuation of pus, pain relieving.Control angina pectoris, menoxenia, dysmenorrhea, amenorrhea, metrorrhagia leukorrhagia, hundred abdominal masss, gather, abdominal pain due to blood stasis, arthralgia, palpitation with fear sleeplessness, malignant boil toxic swelling.
Radix Puerariae: yang invigorating expelling pathogenic factors from muscles, rash antidiarrheal, relieving restlessness is temperature only.Cure the wound cold, warm headache stiffness of the nape, and dysphoria with smothery sensation is quenched one's thirst, and has loose bowels, dysentery, and skin eruption is not saturating, hypertension, and angina pectoris is deaf.
Radix Ginseng: strongly invigorating primordial QI, invigorating the spleen to benefit the lung, promoting the production of body fluid to quench thirst, increasing intelligence of calming the nerves.Cure mainly lose blood greatly, vomit and diarrhoea greatly and occur after serious disease vigour fictitious pole, the deficiency of vital energy is for card that is de-, faint pulse being about to disappear; Lassitude, inappetence, upper abdomen feeling of fullness, vomiting such as to be had loose bowels at the card of deficiency of spleen-QI; Short of breath, card that is weak, the lung qi virtual loss such as asthma, deficient pulse spontaneous perspiration easily of taking action; The card of Tianjin wound such as thirsty, to quench one's thirst; The card of the deficiency of qi and blood such as irritability, insomnia and dreamful sleep, palpitation with fear are forgetful; Sexual impotence card etc. caused by physical weakness.
Fructus Aurantii: dispelling the stagnated QI, row expectorant, removing food stagnancy.Control chest and diaphragm expectorant stagnant, the feeling of stuffiness in chest, coerce swollen, food stagnation, eructation, vomiting, heavy after dysentery, proctoptosis, uterine prolapse.
Radix Glycyrrhizae: with middle emergency, lung moistening, removing toxic substances, coordinating the actions of various ingredients in a prescription.
Radix Ophiopogonis: YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire.For dryness of the lung dry cough, chronic consumptive disease is coughed, and Tianjin wound is thirsty, and vexed insomnia, interior-heat is quenched one's thirst, dryness of the intestine constipation, pharyngeal diphtheria.
Radix Angelicae Sinensis: benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturizes laxation.Control menoxenia, amenorrhea is suffered from abdominal pain, and hundred abdominal mass knots are poly-, metrorrhagia; Headache due to deficiency of blood, dizzy, flaccidity syndrome and arthralgia syndrome; Dryness of the intestine dyschezia is heavy after bloody dysentery; Carbuncle skin ulcer is stolen, injury from falling down.
The Radix Astragali: invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle difficulty is burst, and burst for a long time and do not hold back, blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst; Chronic nephritis proteinuria, diabetes.
Rhizoma Chuanxiong: activating QI to alleviate the depression, method wind-dryness is wet, promoting blood circulation and stopping pain.Controlling air-cooled headache revolves dizzy, and hypochondriac pain abdomen aches, arthralgia due to cold clonic spasm of the muscle, amenorrhea, difficult labour, postpartum stagnation block pain, ulcer sores.For menoxenia, amenorrhea dysmenorrhea, abdominal mass is suffered from abdominal pain, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.
Radix Notoginseng: dissipating blood stasis stops blooding, subduing swelling and relieving pain.For various inside and outside hemorrhage, breast ventral spine pain, tumbling and swelling.
Rhizoma Acori Graminei: have one's ideas straightened out, eliminating phlegm, regulates the flow of vital energy, and invigorates blood circulation, and loose wind, dries.Control epilepsy, syncope due to accumulation of phlegm, calentura coma, forgetful, deafness with qi stagnation, ambition is unhappy, stomachache, stomachache, anemofrigid-damp arthralgia, swollen ulcer drug, traumatic injury.
Rhizoma Corydalis: invigorate blood circulation, dissipating blood stasis, regulates the flow of vital energy, pain relieving.Control all pains of trusted subordinate's waist knee joint, menoxenia, hundred abdominal masss, metrorrhagia, puerperal blood faints, lochiorrhea, traumatic injury.
The Radix Aucklandiae: promoting the circulation of QI to relieve pain, strengthening the spleen to promote digestion.For weighing after breast gastral cavity distending pain, dysentery, food stagnation does not disappear, anorexia.
Semen Persicae: blood stasis removing and clots absorbing, moisturizes laxation.Control amenorrhea, hundred abdominal masss, calentura blood-retention, migratory arthralgia, malaria, traumatic injury, swelling and pain due to blood stasis, the dry constipation of blood.
Radix Paeoniae Rubra: clots absorbing, pain relieving, removing heat from blood, detumescence.Control the stagnant amenorrhea of the stasis of blood, hernia abdominal mass is gathered, stomachache, hypochondriac pain, epistaxis, dysentery, discharging fresh blood stool, conjunctival congestion, carbuncle.
Flos Carthami: promoting blood circulation to restore menstrual flow, blood stasis removing pain relieving.Control amenorrhea, hundred abdominal masss, difficult labour, stillborn fetus, disease that postpartum lochia can't go, blood stasis are had a pain, carbuncle, injury from falling down.
Fructus Trichosanthis: clearing away heat and eliminating phlegm, relieving stuffiness of the chest by dispersing aggregation of pathogens, moisturizes laxation.For cough due to lung-heat, the turbid Huang of expectorant is thick, obstruction of qi in the chest and cardialgia, blocked-up chest feeling of fullness, acute mastitis, lung abscess, and acute appendicitis swells and ache, constipation.
Radix Polygalae: Fructus Alpiniae Oxyphyllae of calming the nerves, eliminates the phlegm, resolving depression.Control palpitation with fear, forgetful, nocturnal emission, insomnia, cough ant phlegm, carbuncle skin ulcer swells.
Ramulus Uncariae Cum Uncis: heat clearing away suppressing the hyperactive liver, relieve dizziness, high fever, infantile convulsions, epilepsy, etc. arresting convulsion.Control pediatric epilepsy scared Chi Zong, adult's slight Hypertension, dizzy, dizzy, married woman's eclamposia.
Oenothera rosea L' Her. Ex Aif: removing toxic substances, blood stasis dispelling, grand pressure.Cure mainly hot carbuncle toxin, coronary heart disease, vascular hypertension.
Herba Dracocephali: lung heat clearing is induced sweat, cool liver hemostasis.For flu, headache, laryngalgia, tracheitis, asthma, jaundice, spits blood, epistaxis, dysentery, heart disease, neurasthenia, lyssodexis.
The Radix Paeoniae Alba: nourishing blood to suppress the hyperactive liver, pain relieving in slow, yin fluid astringing receives antiperspirant.Control the breast abdomen pain over the hypochondriac region, dysentery is suffered from abdominal pain, spontaneous sweating, fever due to yin deficiency, menoxenia, metrorrhagia, leukorrhagia.
The invention has the beneficial effects as follows all medicine compatibilities of the present invention, bring out the best in each other, have and nourish the body, mind tranquilizing and the heart calming, blood circulation promoting and blood stasis dispelling, promoting the circulation of QI to relieve pain, the effect of vital base and primordial QI consolidating, without obvious toxic-side effects, can effectively alleviate and treat coronary heart disease.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described
Physical data
56 routine patients with coronary heart disease are selected to carry out clinical observation to Chinese medicine composition of the present invention.In 56 routine cases, 12 routine angina pectoris patients, 18 routine myocardial infarction patients, 14 routine silent myocardial ischemia type patients, 12 routine heart failure and arrhythmia type patient, all adopt Chinese medicine composition of the present invention to treat, by oral for the decoction medicine decocted, every day potion, twice on the one.
Symptom standard
Effective: symptom disappears completely;
Effective: symptom alleviates;
Invalid: symptom is unchanged.
Table 1 is the curative effect statistical result after treatment:
Table 1
Model case
Case one: Lin, female, 68 years old.Suffer from coronary heart disease more than 30 year, after climacteric, chest distress is obvious, discomfort uncomfortable in chest is felt for a long time at night, and there is slight chest pain phenomenon to occur when self-induction is uncomfortable in chest, uncomfortable in chestly after taking nitroglycerin slightly to alleviate, but consider to take in recent years the frequent and dosage of number of times to strengthen gradually, therefore seek help from treatment by Chinese herbs, time medical, nitroglycerin is taken number of times and is added to twice daily, and interval time of having an attack of one's old illness shortens, die Blausucht, set channels varicose, and pulse is carefully puckery, after taking Chinese medicine composition one and a half months of the present invention, readme above-mentioned symptom takes a turn for the better, inactive nitroglycerin gradually, attack times obviously reduces, former electrocardiogram prompting is by myocardial ischemia st section > 0.12s, crown t ripple, u ripple is inverted, QT time lengthening is to 0.45s, after check, the electrocardiogram prompting QT time returns to 0.40s, u ripple is consistent with main ripple direction.
Case two: cattle, man, 38 years old.Suffer from coronary heart disease and hyperlipidemia 6 years, through often there is severe headache after oral nitrate esters medicine, the persistent period uncomfortable in chest extends gradually.Fat during treatment, thick fur is greasy, die Blausucht, electrocardiogram display myocardial ischemia, lead st section > 0.05mv entirely, coronary insufficiency, takes Chinese medicine composition of the present invention and checks electrocardiogram after one month, and display v1-v3 st section of leading forces down < 0.03mv, nervous, uncomfortable in chest symptom is improved, lip is ruddy, and no headache phenomenon occurs, and in blood fat, triglyceride (TG) is down to 1.6mmol/L by original 2.3mmol/L.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Embodiment 1
Take Radix Salviae Miltiorrhizae 10 parts, Radix Puerariae 10 parts, Radix Ginseng 5 parts, Fructus Aurantii 10 parts, 5 parts, Radix Glycyrrhizae, Radix Ophiopogonis 10 parts, Radix Angelicae Sinensis 15 parts, the Radix Astragali 20 parts, Rhizoma Chuanxiong 10 parts, Radix Notoginseng 5 parts, Rhizoma Acori Graminei 10 parts, Rhizoma Corydalis 5 parts, the Radix Aucklandiae 10 parts, 5 parts, Semen Persicae, Radix Paeoniae Rubra 10 parts, 10 parts, Flos Carthami, Fructus Trichosanthis 5 parts, Radix Polygalae 5 parts, Ramulus Uncariae Cum Uncis 5 parts, oenothera rosea L' Her. Ex Aif 2 parts, Herba Dracocephali 2 parts, the Radix Paeoniae Alba 15 parts, conventionally makes Chinese medicine decoction.
Embodiment 2
Preferably take Radix Salviae Miltiorrhizae 15 parts, Radix Puerariae 20 parts, Radix Ginseng 8 parts, Fructus Aurantii 13 parts, 8 parts, Radix Glycyrrhizae, Radix Ophiopogonis 13 parts, Radix Angelicae Sinensis 17 parts, the Radix Astragali 25 parts, Rhizoma Chuanxiong 12 parts, Radix Notoginseng 9 parts, Rhizoma Acori Graminei 14 parts, Rhizoma Corydalis 10 parts, the Radix Aucklandiae 13 parts, 8 parts, Semen Persicae, Radix Paeoniae Rubra 15 parts, 16 parts, Flos Carthami, Fructus Trichosanthis 8 parts, Radix Polygalae 8 parts, Ramulus Uncariae Cum Uncis 8 parts, oenothera rosea L' Her. Ex Aif 4 parts, Herba Dracocephali 4 parts, the Radix Paeoniae Alba 20 parts, conventionally makes Chinese medicine decoction.
Embodiment 3
Preferably take Radix Salviae Miltiorrhizae 20 parts further, Radix Puerariae 25 parts, Radix Ginseng 10 parts, Fructus Aurantii 15 parts, 10 parts, Radix Glycyrrhizae, Radix Ophiopogonis 15 parts, Radix Angelicae Sinensis 20 parts, the Radix Astragali 30 parts, Rhizoma Chuanxiong 15 parts, Radix Notoginseng 10 parts, Rhizoma Acori Graminei 15 parts, Rhizoma Corydalis 15 parts, the Radix Aucklandiae 15 parts, 10 parts, Semen Persicae, Radix Paeoniae Rubra 20 parts, 15 parts, Flos Carthami, Fructus Trichosanthis 10 parts, Radix Polygalae 10 parts, Ramulus Uncariae Cum Uncis 15 parts, oenothera rosea L' Her. Ex Aif 5 parts, Herba Dracocephali 5 parts, the Radix Paeoniae Alba 25 parts, conventionally makes Chinese medicine decoction.
First medicine is washed, use cold water soak 20-30 minute again, medicine is waterlogged completely, be convenient to the dissolving of effective ingredient, then medicine is placed in the vessel of marmite, pottery or crock and so on and (cannot iron pan and aluminum pot be used), add as medicine 5-10 water doubly, or exceed 2-3 cm than powder.When decocting first pass, after boiled with big fire, then with little fire endure about 20 minutes all right, medicine soup is poured in vessel, then decocts second time.The method of decocting second time is the same with first pass, and just the time can be shorter a little.After having decocted, this twice fried medicine soup is mixed and takes, total amount is greatly about 300-500 milliliter, and patient can take for one day at twice, for the patient of the difficulty that takes traditional Chinese medicine, and can sub-service repeatedly on a small quantity.At period in a medicine, prohibit and eat cold and cool spicy food.
Claims (4)
1. treat the Chinese medicine composition of coronary heart disease for one kind, it is characterized in that, the crude drug making effective ingredient by following weight parts is: Radix Salviae Miltiorrhizae 10-20 part, Radix Puerariae 10-25 part, Radix Ginseng 5-10 part, Fructus Aurantii 10-15 part, Radix Glycyrrhizae 5-10 part, Radix Ophiopogonis 10-15 part, Radix Angelicae Sinensis 15-20 part, Radix Astragali 20-30 part, Rhizoma Chuanxiong 10-15 part, Radix Notoginseng 5-10 part, Rhizoma Acori Graminei 10-15 part, Rhizoma Corydalis 5-15 part, Radix Aucklandiae 10-15 part, Semen Persicae 5-10 part, Radix Paeoniae Rubra 10-20 part, Flos Carthami 10-15 part, Fructus Trichosanthis 5-10 part, Radix Polygalae 5-10 part, Ramulus Uncariae Cum Uncis 5-15 part, oenothera rosea L' Her. Ex Aif 1-5 part, Herba Dracocephali 1-5 part, Radix Paeoniae Alba 15-25 part.
2. narrate according to claims 1, a kind of Chinese medicine composition for the treatment of coronary heart disease, is characterized in that, the crude drug making effective ingredient by following weight parts is: Radix Salviae Miltiorrhizae 20 parts, Radix Puerariae 25 parts, Radix Ginseng 10 parts, Fructus Aurantii 15 parts, 10 parts, Radix Glycyrrhizae, Radix Ophiopogonis 15 parts, Radix Angelicae Sinensis 20 parts, the Radix Astragali 30 parts, Rhizoma Chuanxiong 15 parts, Radix Notoginseng 10 parts, Rhizoma Acori Graminei 15 parts, Rhizoma Corydalis 15 parts, the Radix Aucklandiae 15 parts, 10 parts, Semen Persicae, Radix Paeoniae Rubra 20 parts, 15 parts, Flos Carthami, Fructus Trichosanthis 10 parts, Radix Polygalae 10 parts, Ramulus Uncariae Cum Uncis 15 parts, oenothera rosea L' Her. Ex Aif 5 parts, Herba Dracocephali 5 parts, the Radix Paeoniae Alba 25 parts.
3. narrate according to claims 1, a kind of Chinese medicine composition for the treatment of coronary heart disease, is characterized in that, the crude drug making effective ingredient by following weight parts is: Radix Salviae Miltiorrhizae 15 parts, Radix Puerariae 20 parts, Radix Ginseng 8 parts, Fructus Aurantii 13 parts, 8 parts, Radix Glycyrrhizae, Radix Ophiopogonis 13 parts, Radix Angelicae Sinensis 17 parts, the Radix Astragali 25 parts, Rhizoma Chuanxiong 12 parts, Radix Notoginseng 9 parts, Rhizoma Acori Graminei 14 parts, Rhizoma Corydalis 10 parts, the Radix Aucklandiae 13 parts, 8 parts, Semen Persicae, Radix Paeoniae Rubra 15 parts, 16 parts, Flos Carthami, Fructus Trichosanthis 8 parts, Radix Polygalae 8 parts, Ramulus Uncariae Cum Uncis 8 parts, oenothera rosea L' Her. Ex Aif 4 parts, Herba Dracocephali 4 parts, the Radix Paeoniae Alba 20 parts.
4. narrate according to claims 1, a kind of Chinese medicine composition for the treatment of coronary heart disease, is characterized in that, the crude drug making effective ingredient by following weight parts is: Radix Salviae Miltiorrhizae 10 parts, Radix Puerariae 10 parts, Radix Ginseng 5 parts, Fructus Aurantii 10 parts, 5 parts, Radix Glycyrrhizae, Radix Ophiopogonis 10 parts, Radix Angelicae Sinensis 15 parts, the Radix Astragali 20 parts, Rhizoma Chuanxiong 10 parts, Radix Notoginseng 5 parts, Rhizoma Acori Graminei 10 parts, Rhizoma Corydalis 5 parts, the Radix Aucklandiae 10 parts, 5 parts, Semen Persicae, Radix Paeoniae Rubra 10 parts, 10 parts, Flos Carthami, Fructus Trichosanthis 5 parts, Radix Polygalae 5 parts, Ramulus Uncariae Cum Uncis 5 parts, oenothera rosea L' Her. Ex Aif 2 parts, Herba Dracocephali 2 parts, the Radix Paeoniae Alba 15 parts.
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105232772A (en) * | 2015-10-20 | 2016-01-13 | 刘国霞 | Traditional Chinese medicine for treating cardiovascular diseases and preparing method of traditional Chinese medicine |
| CN105343777A (en) * | 2015-11-27 | 2016-02-24 | 刘兆君 | Heart soothing pills and method for preparing same |
| CN105998610A (en) * | 2016-05-30 | 2016-10-12 | 姚新亮 | Traditional Chinese medicinal composition for treating coronary heart disease and preparation method thereof |
| CN106975056A (en) * | 2017-04-25 | 2017-07-25 | 李兴尧 | A kind of Chinese medicine microbial fermentation preparation and preparation method and application |
| CN108653543A (en) * | 2018-06-18 | 2018-10-16 | 杨塬 | A kind of pharmaceutical composition for treating coronary heart disease |
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2013
- 2013-12-26 CN CN201310727630.4A patent/CN104740268A/en active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105232772A (en) * | 2015-10-20 | 2016-01-13 | 刘国霞 | Traditional Chinese medicine for treating cardiovascular diseases and preparing method of traditional Chinese medicine |
| CN105343777A (en) * | 2015-11-27 | 2016-02-24 | 刘兆君 | Heart soothing pills and method for preparing same |
| CN105998610A (en) * | 2016-05-30 | 2016-10-12 | 姚新亮 | Traditional Chinese medicinal composition for treating coronary heart disease and preparation method thereof |
| CN106975056A (en) * | 2017-04-25 | 2017-07-25 | 李兴尧 | A kind of Chinese medicine microbial fermentation preparation and preparation method and application |
| CN108653543A (en) * | 2018-06-18 | 2018-10-16 | 杨塬 | A kind of pharmaceutical composition for treating coronary heart disease |
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Application publication date: 20150701 |