CN104840930A - Traditional Chinese medicine composition for treating coronary heart disease - Google Patents

Traditional Chinese medicine composition for treating coronary heart disease Download PDF

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CN104840930A
CN104840930A CN201510297966.0A CN201510297966A CN104840930A CN 104840930 A CN104840930 A CN 104840930A CN 201510297966 A CN201510297966 A CN 201510297966A CN 104840930 A CN104840930 A CN 104840930A
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parts
fructus
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heart disease
coronary heart
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夏征梅
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Abstract

The invention provides a traditional Chinese medicine composition for treating coronary heart disease. The traditional Chinese medicine composition comprises 15-30 parts of tea tree roots, 9-15 parts of radix puerariae, 9-12 parts of gingko leaves, 10-20 parts of cassia twig, 10-20 parts of ramulus mori, 15-30 parts of angelica sinensis, 3-9 parts of emblic leafflower fruit, 3-9 parts of rhizoma zingiberis, 3-9 parts of motherwort fruit, 3-9 parts of asarum, 5-10 parts of processed monkshood, 5-9 parts of allium macrostemon, 3-9 parts of sea-buckthorn and 15-30 parts of charred triplet. The traditional Chinese medicine composition provided by the invention is definite in curative effect on coronary heart disease and has a satisfactory result through clinical tests.

Description

A kind of Chinese medicine composition for the treatment of coronary heart disease
Technical field
The invention belongs to technical field of Chinese medicines, be specifically related to a kind of Chinese medicine composition for the treatment of coronary heart disease.
Background technology
Coronary heart disease is the abbreviation of coronary atherosclerotic heart disease, and mostly occur after 40 years old, old people is more.Coronary artery supply heart self-blood, there is seriously atherosis or spasm in coronary artery, makes coronary stricture or obturation, cause myocardial ischemia-anoxemia or infarction, clinical symptoms has uncomfortable in chest, nervous, dyspnea, precordialgia, also has the disease generations such as dizzy, dizzy, tinnitus.Can arrhythmia be there is in severe patient, often because of myocardial ischemia, anoxia and cause myocardium large area downright bad, and threat to life.
Modern medicine is divided into two classes substantially to cardiopathic treatment means: one is use medicine to comprise blood vessel dilating class medicine and the molten lipid drug of thrombolytic; Two is support, bypass surgery.In the treatment of coronary heart disease, intervene operation and bypass surgery all belong to wound treatment, and postoperative complication has a strong impact on the healthy of patient simultaneously.These methods particularly significant in the rescue stage to the treatment of cardiac be effective.But side effect is also comparatively large, especially can not life-time service.
Summary of the invention
The object of the invention is to provide a kind of Chinese medicine composition for the treatment of coronary heart disease, is applicable to coronary heart disease determined curative effect, and safety has no side effect.
Technical solution of the present invention is as follows, a kind of Chinese medicine composition for the treatment of coronary heart disease, and each crude drug component is by weight ratio: Radix Camelliae sinensis 15-30 part, Radix Puerariae 9-15 part, Folium Ginkgo 9-12 part, Ramulus Cinnamomi 10-20 part, Ramulus Mori 10-20 part, Radix Angelicae Sinensis 15-30 part, Fructus Phyllanthi 3-9 part, Rhizoma Zingiberis 3-9 part, Fructus Leonuri 3-9 part, Herba Asari 3-9 part, gun additioner 5-10 part, Bulbus Allii Macrostemonis 5-9 part, Fructus Hippophae 3-9 part, JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata) 15-30 part.
Be decocted in water for oral dose, medicine-feeding adds 500 milliliters, clear water, soaks 30 minutes, boils latter 30 minutes at a simmer, decoct 2 times, and merging medicinal liquid is 1 dose.One day 1 dose, point taking for 2 times, 15 days is a course for the treatment of.
Coronary heart disease is called the thoracic obstruction in the traditional Chinese medical science, and so-called " numbness " is exactly that impatency is obstructed, i.e. coronary artery blockage or narrow.Treatment by Chinese herbs needs that blood circulation promoting and blood stasis dispelling, coronary circulation-promoting pain-relieving medicament composing prescription of the present invention is unique, formula is rigorous, select YAOJING to refine, each component drug synergism, complements each other, and shares Radix Camelliae sinensis, Radix Puerariae, Folium Ginkgo, Ramulus Cinnamomi, Ramulus Mori, Radix Angelicae Sinensis, Fructus Phyllanthi, Rhizoma Zingiberis, Fructus Leonuri, Herba Asari, gun additioner, Bulbus Allii Macrostemonis, JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata), Fructus Hippophae etc., there is warming YANG and promoting blood circulation, blood circulation promoting and blood stasis dispelling, relieving stuffiness of the chest by dispersing aggregation of pathogens, vessel softening, improve myocardial ischemia, improve the effects such as microcirculation.Adhere to using, can alleviate anoxia to the injury of cardiac muscle, help cardiac function to recover, strengthen the protection to blood vessel of human body, stablize the rhythm of the heart and improve the multiple curative effects such as microcirculation, thus improve cardiac function, to ensure that blood normally runs, improve energy metabolism and the supply of cardiac muscle; And blood coagulation and anticoagulation system can be regulated, anti-tampon.Formed and finally reach and fundamentally treats coronary heart diseases and angina pectoris, prevent its recurrent exerbation, the object of prevention myocardial infarction, heart failure and sudden death.
The pharmacological action of each medicine of the present invention is as follows:
Radix Camelliae sinensis, [nature and flavor] are bitter; Cool [return through] heart; The diuresis of kidney channel [function cures mainly] heart tonifying; Promoting blood flow to regulate menstruation; Heat-clearing and toxic substances removing.Main heart disease; Edema; Hepatitis; Dysmenorrhea; Sore swollen toxin; Aphtha; Soup fire is burnt; Herpes zoster; Psoriasis.
Radix Puerariae, [nature and flavor] are sweet, pungent, cool.[return through] returns spleen, stomach warp.[function cures mainly] expelling pathogenic factors from muscles for reducing heat, promotes the production of body fluid, rash, yang invigorating antidiarrheal.For fever caused by exogenous pathogens headache, stiff nape and back, thirsty, quench one's thirst, measles without adequate eruption, hematodiarrhoea, has loose bowels; Hypertension neck pain.
Folium Ginkgo, [nature and flavor] are sweet, bitter, puckery, flat.[return through] GUIXIN, lung meridian.[function cures mainly] astringes the lung, and relievings asthma, blood circulation promoting and blood stasis dispelling, pain relieving.For cough and asthma due to lung deficiency; Coronary heart disease, angina pectoris, hyperlipidemia.
Ramulus Cinnamomi, [nature and flavor] acrid, sweet, warm.[return through] GUIXIN, lung, urinary bladder channel.[function cures mainly] expelling cold and relieving exterior syndrome; Promoting the flow of QI-blood by warming the meridian; Activating YANG and prormoting functioning of QI.Main exterior syndrome due to wind-cold; Arthralgia due to cold-dampnes; Extreme cold of the limbs; Amenorrhea is suffered from abdominal pain; Lump in the abdomen lumps; The thoracic obstruction; Cardiopalmus; Dysuria.For anemofrigid cold, coldness and pain in the epigastrium, cold in blood amenorrhea, arthralgia, phlegm retention water-retention, edema, cardiopalmus, renal mass.
Ramulus Mori, [meridian distribution of property and flavor]: micro-hardship; Property is put down.Enter Liver Channel.[effect and effect]: wind-damp dispelling; The meridian dredging; Row aqueous vapor.Main air pain of dampness syndrome; Apoplexy and hemiplegia; Edema foot gas; Human body pruritus due to wind pathogen.For takeing on arm, joint aches is numb.
Radix Angelicae Sinensis, [nature and flavor] are warm in nature, hide sweet, pungent.[return through] returns liver, the heart, spleen channel.[function cures mainly] is enriched blood and is invigorated blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.Radix Angelicae Sinensis can improve hypercoagulability in body, and adjustment blood lipid metabolism, reduces cholesterol.
Fructus Phyllanthi, [nature and flavor] are sweet, sour, puckery, cool.[return through] attaches to the lung and stomach meridians.[function cures mainly] clearing away heat and cooling blood, promoting digestion and invigorating the stomach, cough-relieving of promoting the production of body fluid.For heat in blood blood stasis, dyspepsia, abdominal distention, cough, laryngalgia, xerostomia.
Rhizoma Zingiberis, [nature and flavor] are pungent, hot.[return through] returns spleen, stomach, kidney, the heart, lung meridian.[function cures mainly] Rhizoma Zingiberis warming spleen and stomach for dispelling cold, recuperating depleted YANG is promoted blood circulation, dampness expectorant.For coldness and pain in the epigastrium, vomiting is had loose bowels, and cold extremities faint pulse, phlegm retention is breathed with cough.
Fructus Leonuri, [nature and flavor] sweet in the mouth; Pungent; Cold nature; Upper poison.[return through] returns Liver Channel.[function] promoting blood flow to regulate menstruation; Liver heat removing and eyesight improving.[curing mainly] menoxenia; Dysmenorrhea; Amenorrhea; The stagnant stomachache of the stasis of blood in puerperal; Liver-heat is had a headache; Dizzy; Conjunctival congestion and swelling pain; The raw cataracta of order.
Herba Asari, [nature and flavor] are pungent, temperature.[return through] GUIXIN, lung, kidney channel.[function cures mainly] expelling wind and cold, understand things pain-stopping, warming the lung to resolve fluid-retention.For anemofrigid cold, headache, toothache, nasal obstruction nasal sinusitis, rheumatic arthralgia, phlegm retention is breathed with cough.
Radix Aconiti Lateralis Preparata, [function cures mainly] recuperating depleted YANG and rescuing the patient from collapse, mend fire supporing yang, dispersing cold for relieving pain.Control excessive YIN keeping YANG externally, loss of YANG due to profuse perspiration, vomiting and diarrhea is fainted inverse, trusted subordinate's cold type of pain, the splenic diarrhea cold-dysentery, beriberi edema children's intermittent infantile convulsion, anemofrigid-damp arthralgia, the contracture of Wei lame, sexual impotence cold womb, the disease of the leakage of carbuncle of yin nature skin ulcer and all chronic diseaseses.
Bulbus Allii Macrostemonis, [nature and flavor] are pungent, bitter, temperature.[return through] returns lung, stomach, large intestine channel.[function cures mainly] activating YANG and eliminating stagnation, circulation of qi promoting intestinal stasis relieving.For thoracic obstruction pain, phlegm retention cough with asthma is heavy after letting out dysentery.
Fructus Hippophae, [nature and flavor] are sour, puckery, temperature.[function cures mainly] eliminating phlegm and stopping cough, relieving dyspepsia, promoting blood circulation to remove blood stasis.For cough with copious phlegm, dyspepsia, abdominal pain due to retention of food, blood stasis amenorrhea, falls and flutters congestive edema.
JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata), the general designation of Massa Medicata Fermentata (parched to brown), Fructus Crataegi (parched to brown), Fructus Hordei Germinatus (parched to brown) three kinds of medicine compatibilities, has spleen benefiting and stimulating the appetite, dyspepsia and intestinal stasis relieving effect.Massa Medicata Fermentata (parched to brown) sweet in the mouth, pungent, property of medicine temperature.Enter spleen, stomach warp.Function invigorating the spleen and regulating the stomach, help digestion adjust in.Being used for the treatment of diet disappears stagnant, feeling of stuffiness in chest abdominal distention, and profit is rushed down in vomiting, and postnatal blood stasis is suffered from abdominal pain, and children's's enlarged abdomen heavily fortified point is long-pending.Fructus Crataegi (parched to brown) sour in the mouth, sweet, property of medicine tepor, returns taste Liver Channel.Function promoting digestion and invigorating the stomach, blood circulation promoting and blood stasis dispelling, convergence dysentery relieving.Be used for the treatment of meat amass phlegm retention, feeling of fullness acid regurgitation, dysentery hemorrhoidal hamorrhage, soreness of waist hernia, puerperal after-pains, lochiorrhea, children's breast food disappear stagnant.Fructus Hordei Germinatus (parched to brown) sweet in the mouth, mild in medicine property.Return taste warp.Function promote qi circulation digestion promoting, spleen benefiting and stimulating the appetite, moves back breast and disappears and rise.Do not disappear for food stagnation, suffer from abdominal distention and pain, human milk silt, distending pain of the breast, women weans.Three taste medicine compatibilities, have food stagnation removing food stagnation effect, for diseases such as inappetence, dyspepsia, gastral cavity painful abdominal mass distensions.
Detailed description of the invention
Below by embodiment and test example, the invention will be further described.But the present invention is not limited to described in embodiment, those of ordinary skill in the art do some amendment, all in scope.
Embodiment 1. 1 kinds treats the Chinese medicine composition of coronary heart disease, and each crude drug component by weight gram proportioning is: Radix Camelliae sinensis 15 grams, Radix Puerariae 9 grams, Folium Ginkgo 9 grams, Ramulus Cinnamomi 10 grams, Ramulus Mori 10 grams, Radix Angelicae Sinensis 15 grams, Fructus Phyllanthi 3 grams, Rhizoma Zingiberis 3 grams, Fructus Leonuri 6 grams, Herba Asari 3 grams, gun additioner 5 grams, Bulbus Allii Macrostemonis 5 grams, Fructus Hippophae 3 grams, JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata) 15 grams.
Be decocted in water for oral dose, medicine-feeding adds 500 milliliters, clear water, soaks 30 minutes, boils latter 30 minutes at a simmer, decoct 2 times, and merging medicinal liquid is 1 dose.One day 1 dose, point taking for 2 times, 15 days is a course for the treatment of.
Embodiment 2. 1 kinds treats the Chinese medicine composition of coronary heart disease, and each crude drug component is by weight ratio: Radix Camelliae sinensis 30 grams, Radix Puerariae 15 grams, Folium Ginkgo 12 grams, Ramulus Cinnamomi 20 grams, Ramulus Mori 20 grams, Radix Angelicae Sinensis 30 grams, Fructus Phyllanthi 9 grams, Rhizoma Zingiberis 9 grams, Fructus Leonuri 10 grams, Herba Asari 9 grams, gun additioner 10 grams, Bulbus Allii Macrostemonis 9 grams, Fructus Hippophae 9 grams, JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata) 30 grams.
Preparation and instructions of taking are with embodiment 1.
Embodiment 3. 1 kinds treats the Chinese medicine composition of coronary heart disease, and each crude drug component is by weight ratio: Radix Camelliae sinensis 25 grams, Radix Puerariae 12 grams, Folium Ginkgo 10 grams, Ramulus Cinnamomi 15 grams, Ramulus Mori 15 grams, Radix Angelicae Sinensis 25 grams, Fructus Phyllanthi 6 grams, Rhizoma Zingiberis 6 grams, Fructus Leonuri 8 grams, Herba Asari 6 grams, gun additioner 8 grams, Bulbus Allii Macrostemonis 7 grams, Fructus Hippophae 6 grams, JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata) 25 grams.
Preparation and instructions of taking are with embodiment 1.
Embodiment 4. 1 kinds treats the Chinese medicine composition of coronary heart disease, and each crude drug component is by weight ratio: Radix Camelliae sinensis 20 grams, Radix Puerariae 10 grams, Folium Ginkgo 10 grams, Ramulus Cinnamomi 14 grams, Ramulus Mori 16 grams, Radix Angelicae Sinensis 20 grams, Fructus Phyllanthi 7 grams, Rhizoma Zingiberis 4 grams, Fructus Leonuri 7 grams, Herba Asari 6 grams, gun additioner 7 grams, Bulbus Allii Macrostemonis 6 grams, Fructus Hippophae 6 grams, JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata) 20 grams.
Preparation and instructions of taking are with embodiment 1.
Embodiment 5. 1 kinds treats the Chinese medicine composition of coronary heart disease, and each crude drug component is by weight ratio: Radix Camelliae sinensis 22 grams, Radix Puerariae 12 grams, Folium Ginkgo 11 grams, Ramulus Cinnamomi 18 grams, Ramulus Mori 12 grams, Radix Angelicae Sinensis 29 grams, Fructus Phyllanthi 7 grams, Rhizoma Zingiberis 5 grams, Fructus Leonuri 9 grams, Herba Asari 5 grams, gun additioner 7 grams, Bulbus Allii Macrostemonis 6 grams, Fructus Hippophae 7 grams, JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata) 22 grams.
Preparation and instructions of taking are with embodiment 1.
The present invention is used for the treatment of coronary heart diseases and angina pectoris, determined curative effect, and achieves promising result through clinical trial.Through making a definite diagnosis, 100 routine patients with coronary heart disease to be treated, total effective rate 97%, and at medication treatments period without finding that there is any untoward reaction and toxic and side effects, showing drug safety, effectively.
The clinical observation of Drug therapy coronary heart disease of the present invention
1, ordinary circumstance
The present inventor accepts outpatient service patients with coronary heart disease totally 100 examples for nearly 3 years for medical treatment, wherein: man 61 example, female 39 example, 56.2 years old mean age.
2, Therapeutic Method
Every day oral medicine of the present invention, within 15 days, be a course for the treatment of, totally 4 courses for the treatment of, drug withdrawal is checked after half a year, and without recurrence for curing (effective), sb.'s illness took a favorable turn is evident as effectively, and it is not obvious that sb.'s illness took a favorable turn is invalid.
3, therapeutic outcome
Observe treatment 60 days, after following up a case by regular visits to half a year, therapeutic effect is in table 1.
Table 1
As can be seen here, curative effect of medication of the present invention is definite, and total effective rate reaches 97.2%.Show through clinical observation: medicine of the present invention has significant curative effect to heart diseases such as coronary heart diseases and angina pectoris, and curative effect is rapid, to angina pectoris, uncomfortable in chest, cardiopalmus, the symptom such as weak, patient generally take medicine once week after can feel obviously to alleviate or disappear, its electrocardiogram, blood pressure, blood fat, blood glucose etc. also obviously improve, to the Liver and kidney function of patient and hemopoietic system has no abnormal changes and untoward reaction, after drug withdrawal, the state of an illness does not occur " bounce-back ".
Model case:
1, patient Wang, male, 62 years old.Patient is in repeatedly occurring over 6 years that anterior part of chest has an intense pain, and companion's feeling of chest tightness, accompanies perspiration, heart beating during outbreak, there is left shoulder and left upper extremity pain simultaneously, each outbreak continues 2-3 minute, alleviates after sublingual administration acid glycerol, and when work strain or fatigue, outbreak is frequent.It is reported that patient has more than ten years of hypertension history, fluctuation of blood pressure, between 21.3/13.3-22.6/14.7kPa (160/100-200/110mmHg), accompanies dizzy headache.Take once in a while " hypertension pill ".Patient is at ordinary times addicted to cigarette, wine, and cigarette wraps every day 1/2-1, and wine is a small amount of, eating greasiness food.Take medicine of the present invention two months above-mentioned symptoms to disappear, continue to take half a year without recurrence.
2, patient Lee so-and-so, male, 49 years old.Main suit is interrupted uncomfortable in chest, cardiopalmus.Occurred uncomfortable in chest without obvious inducement before 5 days, cardiopalmus, companioned with headache is felt sick, and has obvious awareness of defecation, continues about to alleviate after half an hour, without chest and back pain, vomits without profuse sweating.Go to a doctor in local hospital, measuring blood pressure 160/100mmHg.Since idiopathy, repeatedly there is precordial fullness pain without obvious inducement, accompanied left back pain, "dead" pain, can alleviate after continuing about 2-3 minute.Be diagnosed as coronary heart disease, unstable angina pectoris.Patient has gastritis about 15 years.Smoking history 30 years, drinks irregular.Give Drug therapy of the present invention after one month blood pressure recover normal, various symptom obviously alleviates, and is taking one month, recovery from illness.
3, patient Lee, 70 years old, when patient Yu Chen plays activity, there is chest pain suddenly in women, for under xiphoid-process, discontinuity squeezing property pain is uncomfortable, interval is about outbreak in 10-20 minute, and Symptoms last is about 10-20 minute, accompany uncomfortable in chest, gas is tight, profuse sweating, pain is shoulder reflexive pain left, and unconscious obstacle, without fear of cold, heating, feels sick, vomiting, without abdominal distention, admission, measuring blood pressure 160/100mmHg.Patient has hypertension history 7 years, and History of Coronary Heart Disease 1 year, has similar paresthesia epilepsy before telling 1 year, and be hospitalized for treatment, and is diagnosed as " coronary heart disease ", the scorching history of chronic bronchitis 3 years.Give Drug therapy of the present invention after one month blood pressure recover normal, various symptom obviously alleviates, and takes two months continuously, recovery from illness.

Claims (2)

1. treat a Chinese medicine composition for coronary heart disease, it is characterized in that, each crude drug component is by weight ratio: Radix Camelliae sinensis 15-30 part, Radix Puerariae 9-15 part, Folium Ginkgo 9-12 part, Ramulus Cinnamomi 10-20 part, Ramulus Mori 10-20 part, Radix Angelicae Sinensis 15-30 part, Fructus Phyllanthi 3-9 part, Rhizoma Zingiberis 3-9 part, Fructus Leonuri 6-10 part, Herba Asari 3-9 part, gun additioner 5-10 part, Bulbus Allii Macrostemonis 5-9 part, Fructus Hippophae 3-9 part, JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata) 15-30 part.
2. a kind of Chinese medicine composition for the treatment of coronary heart disease as claimed in claim 1, it is characterized in that, each crude drug component is by weight ratio: Radix Camelliae sinensis 25 parts, Radix Puerariae 12 parts, Folium Ginkgo 10 parts, Ramulus Cinnamomi 15 parts, Ramulus Mori 10-20 part, Radix Angelicae Sinensis 25 parts, Fructus Phyllanthi 6 parts, Rhizoma Zingiberis 6 parts, Fructus Leonuri 8 parts, Herba Asari 6 parts, gun additioner 8 parts, Bulbus Allii Macrostemonis 7 parts, Fructus Hippophae 6 parts, JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata) 25 parts.
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Application publication date: 20150819