CN103751642A - Traditional Chinese medicine composition for treating gout - Google Patents

Abstract

The invention relates to a traditional Chinese medicine composition for treating gout. The traditional Chinese medicine composition is characterized by comprising the following components by weight: 10-20 g of ramulus mori, 5-15 g of radix angelicae, 20-40 g of semen coicis, 5-25 g of poria cocos, 5-25 g of bran fried atractylodes, 5-15 g of frankincense, 5-15 g of myrrh, 5-15 g of safflower carthamus, 3-12 g of honeycomb, 5-15 g of broiled black snake, 3-12 g of large-leaved gentian, 3-12 g of ground beeltle, 10-25 g of wined white peony roots, 10-20 g of angelica sinensis, 5-15 g of radices sileris, 10-25 g of medicinal cyathula roots, 10-20 g of cassia twig, 15-30 g of astragalus membranaceus, 10-20 g of gypsum and 5-15 g of liquorice. Compared with the prior art, starting from the spleen and kidney, the traditional Chinese medicine composition adopts the method of treating both symptoms and root causes to enable purine metabolism in vivo to be stimulated and enhanced via invigorating the circulation of blood and removing stasis, and clearing away heat and eliminating dampness, so as to enable full recovery to normal metaboilic level; as for acute attack of the gout, the traditional Chinese medicine composition can quickly relieve pain and reduce swelling, is obvious in the curative effect, and has no any toxic or side effect; after drug discontinuance, the blood uric acid is not easy to rebound, urate is prevented from being deposited in joints and renal parenchyma, and the traditional Chinese medicine composition has a very good treatment effect on the gout, has fewer side effects, and is accepted by the patients easily.

Description

A kind of Chinese medicine composition for the treatment of gout

Technical field

The present invention relates to a kind of Chinese medicine composition, specifically refer to a kind of Chinese medicine composition for the treatment of gout.

Background technology

Gout (gout) is due to purine metabolic disturbance in body or underexcretion, causes uric acid joint etc. to locate a kind of crystallographic arthrosis that deposition causes in vivo.Its distinctive pathological change is uric acid sodium salt deposition, and pathological changes mainly occurs in the positions such as the more rare collagenous tissue of articular cartilage, epiphysis, synovial membrane, tendon, blood vessel and kidney.Gout can betide any age level, but modal patient is 40 years old above middle-aged male.Women is because body inner estrogen can promote urate excretion, and the effect that has inhibition arthritis to show effect, and therefore morbidity is less than male.

Gout, the traditional Chinese medical science claims pyretic arthralgia.Pyretic arthralgia is plain body preponderance of YANG QI, inside has intrinsic heat, or the body of hyperactivity of YANG due to deficiency of YIN, being invaded by exogenous pathogen invasion and attack, pathogen entering the interior heat-transformation, multiple abscess meridians joint; Or wind-cold damp pathogen is with the passing of time touching does not heal, heresy is stayed passages through which vital energy circulates, and portion stays heat-transformation, the resistance of QI and blood numbness, with arthralgia, local scorching hot, red and swollen, bitterly can not touch, can not bend and stretch, obtain cold relaxing for the disease of feature.Can relate to one or more joints.Pathogenic heat causes numbness and can singlely occur, or heat and wetting phase knot, and damp and hot impatency, shows as joint or muscle red and swollen heat pain, and joint stuffiness, walks with difficulty, and can repeatedly show effect.

Summary of the invention

Technical problem to be solved by this invention be for the present situation of prior art a kind of good effect, instant effect are provided and can not recur, the Chinese medicine composition for the treatment of gout that side effect is little.

The present invention solves the problems of the technologies described above adopted technical scheme: the Chinese medicine composition of this treatment gout, is characterized in that being comprised of following weight component:

In above-mentioned Chinese medicine composition, for the principal element of illness, carry out heat clearing away, dredging collateral, Eradicates wind, dehumidifying; Monarch drug take Ramulus Mori, Gypsum Fibrosum, Olibanum (processed), Myrrha (processed), Flos Carthami, process Zaocys, Eupolyphaga Seu Steleophaga, the Radix Angelicae Dahuricae, Radix Gentianae Macrophyllae, Nidus Vespae, Radix Saposhnikoviae, Poria, Rhizoma Atractylodis Macrocephalae (parched with bran), Semen Coicis as main; Ministerial drug adopts Ramulus Cinnamomi, the Radix Astragali, Radix Angelicae Sinensis, the Radix Paeoniae Alba; Radix Cyathulae is adjuvant drug, has the effect that eliminating blood stasis and inducing menstruation is held concurrently, priming enters lower limb; Radix Glycyrrhizae makes medicine, has coordinating the actions of various ingredients in a prescription, makes each efficacy of drugs produce synergism.

Wherein:

Ramulus Mori, nature and flavor hardship, flat, enters Liver Channel, has the effect of heat clearing away, wind-damp dispelling, sharp joint, row aqueous vapor, dredging collateral.Cure mainly anemofrigid-damp arthralgia, spasm of the limbs, beriberi edema, human body pruritus due to wind pathogen.

The Radix Angelicae Dahuricae, nature and flavor are pungent, warm; Return stomach, large intestine, lung meridian; Have dispel the wind, the effect of dampness, detumescence and apocenosis, understand things pain-stopping.Cure mainly headache, supraorbital bone pain, toothache, nasal sinusitis, cold-damp stomachache, hemorrhoidal hamorrhage anal fistula, leucorrhea with red and white discharge, ulcer sores, skin pruritus due to dryness, scabies.

Semen Coicis, property slightly sweet flavor, micro-cool; Enter spleen, stomach, lung, kidney, large intestine channel; Have that spleen invigorating, tonifying the lung, heat clearing away, dampness removing, detumescence, spleen invigorating are dried, the effect such as arthralgia relieving by relaxing muscles and tendons, antibacterial, antiviral, cure mainly the diseases such as insufficiency of the spleen diarrhoea, muscle acid weight, arthralgia.

Rhizoma Smilacis Glabrae, nature and flavor are sweet, light, flat; Return liver, stomach warp.There is the effect of dehumidifying, removing toxic substances, easing joint movement; Cure mainly limbs contracture, muscles and bones contracture pain, scrofula, skin infection due to damp and hot stranguria with turbid discharge, leukorrhagia, carbuncle, scrofula, scabies, syphilis and mercurialism.

Rhizoma Atractylodis Macrocephalae (parched with bran), through the Rhizoma Atractylodis Macrocephalae of Testa Tritici parch; Nature and flavor hardship, sweet, warm; Enter spleen, stomach warp; There is the effects such as invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive, detumescence; Cure mainly that insufficiency of the spleen lack of appetite, abdominal distention are had loose bowels, phlegm retention, vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.

Olibanum (processed), has another name called Olibanum, your fragrant, smoked Lu Xiang, many gals Luo Xiang, bathes fragrantly etc., and nature and flavor are arduous, warm; Enter the heart, spleen, Liver Channel; There is regulating qi and activating blood, analgesic therapy, chase after the effects such as poison, cure mainly the diseases such as coagulation of QI-blood, trusted subordinate's pain, carbuncle pyogenic infections from tumour or sore, traumatic injury, dysmenorrhea, postnatal blood stasis twinge.

Myrrha (processed), has another name called Myrrha, myrrh, bright Myrrha; Nature and flavor hardship, flat; Enter liver, spleen, the heart, kidney channel; There is the effects such as promoting blood circulation and stopping pain, detumescence and promoting granulation; Cure mainly diseases such as falling damage, incised wound, muscles and bones, all Tong, of trusted subordinate mass in the abdomen, amenorrhea, ulcer sore pain, anal fistula, diseases of the eye.

Flos Carthami, nature and flavor are pungent, warm; GUIXIN, Liver Channel; There is the effect that the fragrant row of gas falls apart, enters blood system tool, promoting blood circulation to restore menstrual flow, blood stasis dispelling, pain relieving; Cure mainly the diseases such as dysmenorrhea, amenorrhea, puerperal blood faints, the stagnant stomachache of the stasis of blood, obstruction of qi in the chest and cardialgia, accumulation of blood, traumatic injury congestive edema, arthralgia, paralysis due to windstroke, macular eruption being dark-purple.

Nidus Vespae, has another name called the nest that Nidus Vespae, hornet's nest, Nidus Vespae, wild bee nest, hornet's nest, hundred are worn; Nature and flavor are pungent, flat, poisonous; Return liver, lung meridian.There is the effects such as wind-expelling pain-stopping, detoxicating and killing parasites; Cure mainly infantile convulsion, migratory arthralgia, urticaria pruritus, acute mastitis, furunculosis, scrofula, anal fistula, acute toothache, tinea capitis, honeybee and sting the diseases such as swollen pain.

Radix Cyathulae, property is flat, sweet and slightly bitter taste; Enter liver, kidney two warps; Have dispel the wind, dampness removing, the effect such as stimulate the menstrual flow, invigorate blood circulation; Cure mainly the diseases such as rheumatism waist, knee joint pain, foot flaccidity clonic spasm of the muscle, stranguria with blood, hematuria, women's amenorrhea lump in the abdomen, lump in the abdomen, retention of placenta, arthralgia, injury from falling down.

Process Zaocys, have another name called Zaocys, zaocys dhumnades; Property sweet-salty, flat; Enter lung, spleen two warps; There is the effect of wind-damp dispelling, the meridian dredging; Cure mainly the diseases such as rheumatoid arthritis stubborn, numbness of the skin, bone, tuberculosis of joint, rubella scabies, leprosy, tetanus, poliomyelitis.

Ramulus Cinnamomi, property acrid-sweet flavor, temperature; Enter the heart, lung, urinary bladder channel; There is the effect of diaphoresis expelling pathogenic factors from muscles, warming the meridian and promoting blood circulation; Cure mainly the diseases such as exterior syndrome due to wind-cold, shoulder back of the body podomere ache, thoracic obstruction phlegm retention, amenorrhea lump in the abdomen.

The Radix Astragali, nature and flavor are sweet, tepor; Enter lung, spleen channel; There is spleen invigorating invigorating middle warmer, ascending up spleen-Qi and Yang, benefit and defend the effects such as consolidating superficial resistance, diuresis, poison holding, granulation promoting; Cure mainly the diseases such as the deficiency of vital energy is weak, chronic diarrhea proctoptosis, spontaneous perspiration, edema, sub-official's prolapsus, chronic nephritis proteinuria, diabetes, open sore part disunion of a specified duration.

Radix Gentianae Macrophyllae, nature and flavor toil, flat; Enter liver, stomach, gallbladder meridian; There is the effects such as expelling wind and removing dampness and blood relaxing muscles and tendons, clearing away heat and promoting diuresis; Cure mainly rheumatic arthralgia, muscles and bones contracture, jaundice, have blood in stool, the disease such as osteopyrexia and fever, children's's infantile malnutrition with fever, dysuria.

Eupolyphaga Seu Steleophaga, has another name called eupolyphoge sinensis, and nature and flavor are salty, cold, slightly poisonous; Enter Liver Channel; There is the effect of removing blood stasis with potent drugs blood, reuniting the fractured tendons and bones; Cure mainly the diseases such as injured bone, blood stasis amenorrhea, lump in the abdomen mass in the abdomen.

Radix Paeoniae Alba sprays yellow wine and mixes thoroughly on the Radix Paeoniae Alba, slightly vexed after, put in pot by slow fire heating, fried dry, take out to cool and obtain Radix Paeoniae Alba.Nature and flavor hardship, acid, be slightly cold; Enter liver, spleen two warps, there is the effects such as nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing receipts antiperspirant, cure mainly the breast abdomen pain over the hypochondriac region, dysentery stomachache, spontaneous sweating, fever due to yin deficiency, menoxenia, metrorrhagia, be with inferior disease.

Radix Angelicae Sinensis, nature and flavor are pungent, sweet, warm; Enter liver, the heart, spleen channel; The effects such as having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation; Cure mainly the diseases such as blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.

Radix Saposhnikoviae, acrid in the mouth, sweet; Slightly warm in nature; Enter bladder, liver, spleen channel; There is expelling pathogenic wind from the body surface, removing damp and stopping pain, the effects such as soothing the liver spasmolytic, killing parasites for relieving itching; Cure mainly that affection of exogenous wind-cold, headache stiffness of the nape, dizzy dusk are puckery, anemofrigid-damp arthralgia, joint are ached, stomachache is had loose bowels, difficult saturating, the rubella pruritus of discharging fresh blood stool, broken damaging the spleen and stomach wind, measles, skin infection from the beginning of etc. disease.

Gypsum Fibrosum, nature and flavor are sweet, pungent, Great Cold; Return lung meridian, stomach warp; There is the effects such as clearing away heat-fire, relieving restlessness quench the thirst, heat-clearing and toxic substances removing; Cure mainly that fever caused by exogenous pathogenic factors, high hot excessive thirst, dyspnea and cough due to lung-heat, the high Sheng of stomach-fire, calentura high fever are not moved back, vexed coma, delirium are gone mad, thirsty and dry pharynx, lung-heat dyspnea with rapid respiration, heatstroke spontaneous perspiration, stomach-fire headache, toothache due to stomach-fire, hyperactivity of toxic heat, send out speckle dermexanthesis, aphtha of the mouth and tongue, ulcer sores, burst do not close up, the disease such as the burning hot wound of soup.

Radix Glycyrrhizae, nature and flavor are sweet, flat; Enter spleen, stomach, lung meridian; Have and the effects such as middle emergency, lung moistening, removing toxic substances; Control the diseases such as weakness of the spleen and stomach, lack of appetite, stomachache loose stool, overstrain heating, consumptive lung disease cough, cardiopalmus, infantile convulsion, laryngopharynx swelling and pain, peptic ulcer, ulcer sores, solution poison of drug and alimentary toxicosis.In the present invention, Radix Glycyrrhizae, can coordinating the actions of various ingredients in a prescription as making medicine.

Drug component of the present invention and consumption be few sums up through inventor's long-term clinical application and after having carried out groping in a large number, having adjusted and draws.Conventionally, each component can obtain better curative effect when following dosage.

The important using method of the present invention is conventional decocting, obtains after water preparation oral.Certainly, also can make as required oral liquid, pill or other dosage form.

According to the infective use of this medicine in recent years, added up 89 routine patient with gout and used the treatment situation after this medicine.Wherein asymptomatic hyperuricemia 9 examples, experimental study 32 examples, tophus and chronic gout arthritis 48 examples.Taking this medicine after three months, treatment group total effective rate is 96.7%, wherein cure rate 60%, obvious effective rate 26.7%, effective percentage 10%.

So-called recovery from illness refers to gout transference cure, and without recurrence.What is called is effective refers to that symptom alleviates, and what is called effectively refers to that subjective symptoms takes a turn for the better.

Compared with prior art, the present invention adopts treating both the principal and secondary aspects of a disease, by blood circulation promoting and dispersing pathogen accumulation, clearing away heat and eliminating dampness, from spleen kidney, starts with, and makes purine metabolism in body be excited and strengthen, and makes it to return to homergy level comprehensively.During for gout acute attack, energy alleviating pain and detumescence rapidly, evident in efficacy, and without any side effects, after drug withdrawal, blood uric acid is difficult for bounce-back, and prevents, in urate deposition joint and excess of the kidney matter, gout being had to good therapeutic effect, and side effect is less, easily by patient, accepted.

The specific embodiment

Below in conjunction with embodiment, the present invention is described in further detail.

Preparation example 1

Preparation example 2

Preparation example 3

Case report:

1, Huang, man, 65 years old, 165 centimetres of heights, 80 kilograms of body weight, psychentonia, hyperphagia, fatigue, excessive drinking, there is damage in joint.Suddenly, joint has an intense pain onset, occurs Hong Zhong inflammation heat after one hour, and tenderness and motion limits, approximately disappear gradually through a few days or several weeks, and joint motion and profile thereof can be recovered.Be diagnosed as experimental study.

Take continuously preparation example and cure after 1 three months, within 3 years so far, pass by without recurrence, and all find no side effect generation after taking process and healing.

2, Liu, man, 48 years old, 172 centimetres of heights, 86 kilograms of body weight.Surfeit rich and fatty diet at ordinary times, retention of damp-heat in the interior, diseases caused by exogenous pathogenic factor ailment said due to cold or exposure, invasion and attack meridians, QI and blood can not be unimpeded; Be apt to occur in female toe and Plantar toe joint, inferior is other joint of foot and ankle, hands, wrist, knee joint, elbow joint.Be diagnosed as chronic gout arthritis.Blood test, the uric acid concentration in blood is higher; X-ray inspection, near osteoepiphyseal portion articular surface has round defect.

Take continuously preparation example and cure after 1 three months, so far without recurrence, and all find no side effect generation after taking process and healing.

3, Wang, female, 52 years old, 158 centimetres of heights, 75 kilograms of body weight, start to occur acute pain evening, and patient's pain from dream is waken up, and there is serious red and swollen heat pain phenomenon in joint, simultaneously with fever symptoms.Be diagnosed as experimental study.

Take continuously preparation example and cure after 2 three months, take again preparation example 1 one months.So far 3 years in the past, without recurrence, and all finds no side effect generation after taking process and healing.

4, grandson, female 55 years old, 165 centimetres of heights, 69 kilograms of body weight.Chronic gout arthritis, doctor trained in Western medicine checks that the uric acid concentration in blood is higher, foot joint distortion, wears footwear difficulty.Be diagnosed as tophus and chronic gout arthritis.

Take preparation example 3 three months, red, swollen, hot, the pain in joint disappear, and can wear footwear; Continue to take after two months gout transference cure.

Claims (2)

1. treat a Chinese medicine composition for gout, it is characterized in that being formed by following weight component:

2. the Chinese medicine composition for the treatment of gout according to claim 1, is characterized in that being comprised of following weight component: