CN103751642B - A kind of Chinese medicine composition for the treatment of gout - Google Patents

A kind of Chinese medicine composition for the treatment of gout Download PDF

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CN103751642B
CN103751642B CN201410058353.7A CN201410058353A CN103751642B CN 103751642 B CN103751642 B CN 103751642B CN 201410058353 A CN201410058353 A CN 201410058353A CN 103751642 B CN103751642 B CN 103751642B
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radix
gout
blood
chinese medicine
pain
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CN103751642A (en
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谭曜
郭利平
李锦华
陈易辉
李冰
单伟光
陈静
章雨燕
郑生癸
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谭曜
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Abstract

The present invention relates to a kind of Chinese medicine composition for the treatment of gout, it is characterized in that being made up of following weight component: Ramulus Mori 10 ~ 20g, the Radix Angelicae Dahuricae 5 ~ 15g, Semen Coicis 20 ~ 40g, Poria 5 ~ 25g, Rhizoma Atractylodis Macrocephalae (parched with bran) 5 ~ 25g, Olibanum (processed) 5 ~ 15g Myrrha (processed) 5 ~ 15g, Flos Carthami 5 ~ 15g, Nidus Vespae 3 ~ 12g, process Zaocys 5 ~ 15g, Radix Gentianae Macrophyllae 3 ~ 12g, Eupolyphaga Seu Steleophaga 3 ~ 12g, Radix Paeoniae Alba 10 ~ 25g, Radix Angelicae Sinensis 10 ~ 20g, Radix Saposhnikoviae 5 ~ 15g, Radix Cyathulae 10 ~ 25g, Ramulus Cinnamomi 10 ~ 20g, the Radix Astragali 15 ~ 30g Gypsum Fibrosum 10 ~ 20g and Radix Glycyrrhizae 5 ~ 15g.Compared with prior art, the present invention adopts treating both the principal and secondary aspects of a disease, by blood circulation promoting and dispersing pathogen accumulation, clearing away heat and eliminating dampness, starts with from spleen kidney, makes purine metabolism in body be excited and strengthen, and makes it to return to homergy level comprehensively.For the alleviating pain and detumescence rapidly of energy during gout acute attack, evident in efficacy, and without any side effects, after drug withdrawal, blood uric acid not easily rebounds, and prevents, in urate deposition joint and excess of the kidney matter, having good therapeutic effect to gout, and side effect is less, easily accepted by patient.

Description

A kind of Chinese medicine composition for the treatment of gout
Technical field
The present invention relates to a kind of Chinese medicine composition, specifically refer to a kind of Chinese medicine composition for the treatment of gout.
Background technology
Gout (gout) is due to purine metabolic disturbance in body or underexcretion, causes uric acid place's deposition such as joint and a kind of crystallographic arthrosis of causing in vivo.Its distinctive pathological change is Monosodium urate mineralization, and pathological changes mainly occurs in the more rare position such as collagenous tissue and kidney of articular cartilage, epiphysis, synovial membrane, tendon, blood vessel.Gout can betide any age level, but modal patient is the middle-aged male of more than 40 years old.Women can promote urate excretion due to body inner estrogen, and has the effect suppressing arthritis outbreak, and therefore morbidity is less than male.
Gout, the traditional Chinese medical science claims pyretic arthralgia.Pyretic arthralgia system ferritic preponderance of YANG QI, inside has intrinsic heat, or the body of hyperactivity of YANG due to deficiency of YIN, and being invaded by exogenous pathogen is attacked, pathogen entering the interior heat-transformation, multiple abscess meridians joint; Or wind-cold damp pathogen is with the passing of time touching does not heal, heresy stays passages through which vital energy circulates, and portion stays heat-transformation, and QI and blood numbness hinders, and with arthralgia, local is scorching hot, red and swollen, bitterly can not touch, and can not bend and stretch, obtain cold, relax for the disease of feature.One or more joint can be related to.Pathogenic heat causes numbness and can singlely occur, or heat and wetting phase tie, damp and hot impatency, show as joint or muscle red and swollen heat pain, joint stuffiness, walks with difficulty, can recurrent exerbation.
Summary of the invention
Technical problem to be solved by this invention be for the present situation of prior art provide a kind of good effect, instant effect and can not recur, the Chinese medicine composition for the treatment of gout that side effect is little.
The present invention solves the problems of the technologies described above adopted technical scheme: the Chinese medicine composition of this treatment gout, it is characterized in that being made up of following weight component:
In above-mentioned Chinese medicine composition, the principal element for illness carries out heat clearing away, dredging collateral, Eradicates wind, dehumidifying; Monarch drug based on Ramulus Mori, Gypsum Fibrosum, Olibanum (processed), Myrrha (processed), Flos Carthami, process Zaocys, Eupolyphaga Seu Steleophaga, the Radix Angelicae Dahuricae, Radix Gentianae Macrophyllae, Nidus Vespae, Radix Saposhnikoviae, Poria, Rhizoma Atractylodis Macrocephalae (parched with bran), Semen Coicis; Ministerial drug adopts Ramulus Cinnamomi, the Radix Astragali, Radix Angelicae Sinensis, the Radix Paeoniae Alba; Radix Cyathulae is adjuvant drug, has the effect that eliminating blood stasis and inducing menstruation is held concurrently, priming enters lower limb; Radix Glycyrrhizae makes medicine, has coordinating the actions of various ingredients in a prescription, makes each efficacy of drugs produce synergism.
Wherein:
Ramulus Mori, nature and flavor are bitter, flat, enter Liver Channel, have effect of heat clearing away, wind-damp dispelling, sharp joint, row aqueous vapor, dredging collateral.Cure mainly anemofrigid-damp arthralgia, spasm of the limbs, beriberi edema, human body pruritus due to wind pathogen.
The Radix Angelicae Dahuricae, nature and flavor are pungent, warm; Return stomach, large intestine, lung meridian; Have dispel the wind, effect of dampness, detumescence and apocenosis, understand things pain-stopping.Cure mainly headache, supraorbital bone pain, toothache, nasal sinusitis, cold-damp stomachache, hemorrhoidal hamorrhage anal fistula, leucorrhea with red and white discharge, ulcer sores, skin pruritus due to dryness, scabies.
Semen Coicis is property slightly sweet flavor, micro-cool; Enter spleen, stomach, lung, kidney, large intestine channel; There is spleen invigorating, tonifying the lung, heat clearing away, dampness removing, detumescence, spleen invigorating dried, the effect such as arthralgia relieving by relaxing muscles and tendons, antibacterial, antiviral, cure mainly the disease such as insufficiency of the spleen diarrhoea, muscle acid weight, arthralgia.
Rhizoma Smilacis Glabrae, nature and flavor are sweet, light, flat; Return liver, stomach warp.There is effect of dehumidifying, removing toxic substances, easing joint movement; Cure mainly the limbs contracture caused by damp and hot stranguria with turbid discharge, leukorrhagia, carbuncle, scrofula, scabies, syphilis and mercurialism, muscles and bones contracture pain, scrofula, skin infection.
Rhizoma Atractylodis Macrocephalae (parched with bran), namely through the Rhizoma Atractylodis Macrocephalae of Testa Tritici parch; Nature and flavor are bitter, sweet, warm; Enter spleen, stomach warp; There is the effects such as invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive, detumescence; Cure mainly insufficiency of the spleen lack of appetite, abdominal distention had loose bowels, phlegm retention, vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.
Olibanum (processed), have another name called Olibanum, your fragrant, smoked Lu Xiang, many gals Luo Xiang, bath fragrant etc., nature and flavor are arduous, warm; Enter the heart, spleen, Liver Channel; There is regulating qi and activating blood, analgesic therapy, chase after the effects such as poison, cure mainly the diseases such as coagulation of QI-blood, trusted subordinate's pain, carbuncle pyogenic infections from tumour or sore, traumatic injury, dysmenorrhea, postnatal blood stasis twinge.
Myrrha (processed), has another name called Myrrha, myrrh, bright Myrrha; Nature and flavor are bitter, flat; Enter liver, spleen, the heart, kidney channel; There is the effect such as promoting blood circulation and stopping pain, detumescence and promoting granulation; Cure mainly diseases such as falling damage, incised wound, muscles and bones, trusted subordinate all Tong, mass in the abdomen, amenorrhea, ulcer sore pain, anal fistula, diseases of the eye.
Flos Carthami, nature and flavor are pungent, warm; GUIXIN, Liver Channel; There is effect of gas perfume capable fall apart, enter blood system tool, promoting blood circulation to restore menstrual flow, blood stasis dispelling, pain relieving; Cure mainly the diseases such as dysmenorrhea, amenorrhea, puerperal blood faints, the stagnant stomachache of the stasis of blood, obstruction of qi in the chest and cardialgia, accumulation of blood, traumatic injury congestive edema, arthralgia, paralysis due to windstroke, macular eruption being dark-purple.
Nidus Vespae, has another name called Nidus Vespae, nest that hornet's nest, Nidus Vespae, wild bee nest, hornet's nest, hundred are worn; Nature and flavor are pungent, flat, poisonous; Return liver, lung meridian.There is the effect such as wind-expelling pain-stopping, detoxicating and killing parasites; Cure mainly infantile convulsion, migratory arthralgia, urticaria pruritus, acute mastitis, furunculosis, scrofula, anal fistula, acute toothache, tinea capitis, honeybee sting the diseases such as swollen pain.
Radix Cyathulae, property is put down, sweet and slightly bitter taste; Enter liver, kidney two warp; Have dispel the wind, dampness removing, stimulate the menstrual flow, the effect such as to invigorate blood circulation; Cure mainly the diseases such as rheumatism waist, knee joint pain, foot flaccidity clonic spasm of the muscle, stranguria with blood, hematuria, women's amenorrhea lump in the abdomen, lump in the abdomen, retention of placenta, arthralgia, injury from falling down.
Process Zaocys, have another name called Zaocys, zaocys dhumnades; Property sweet-salty, flat; Enter lung, spleen two warp; There is effect of wind-damp dispelling, the meridian dredging; Cure mainly the diseases such as rheumatoid arthritis stubborn, numbness of the skin, bone, tuberculosis of joint, rubella scabies, leprosy, tetanus, poliomyelitis.
Ramulus Cinnamomi, property acrid-sweet flavor, temperature; Enter the heart, lung, urinary bladder channel; There is effect of diaphoresis expelling pathogenic factors from muscles, warming the meridian and promoting blood circulation; Cure mainly the diseases such as exterior syndrome due to wind-cold, shoulder back of the body podomere ache, thoracic obstruction phlegm retention, amenorrhea lump in the abdomen.
The Radix Astragali, nature and flavor are sweet, tepor; Enter lung, spleen channel; There is spleen invigorating invigorating middle warmer, ascending up spleen-Qi and Yang, benefit defend the effects such as consolidating superficial resistance, diuresis, poison holding, granulation promoting; Cure mainly the diseases such as the deficiency of vital energy is weak, chronic diarrhea proctoptosis, spontaneous perspiration, edema, sub-official prolapsus, chronic nephritis proteinuria, diabetes, open sore part disunion of a specified duration.
Radix Gentianae Macrophyllae is nature and flavor toil, flat; Enter liver, stomach, gallbladder meridian; There is the effect such as expelling wind and removing dampness and blood relaxing muscles and tendons, clearing away heat and promoting diuresis; Cure mainly rheumatic arthralgia, muscles and bones contracture, jaundice, have blood in stool, the disease such as osteopyrexia and fever, children's's infantile malnutrition with fever, dysuria.
Eupolyphaga Seu Steleophaga, has another name called eupolyphoge sinensis, and nature and flavor are salty, cold, slightly poisonous; Enter Liver Channel; There is effect of removing blood stasis with potent drugs blood, reuniting the fractured tendons and bones; Cure mainly the diseases such as injured bone, blood stasis amenorrhea, lump in the abdomen mass in the abdomen.
Radix Paeoniae Alba, namely sprays yellow wine and mixes thoroughly on the Radix Paeoniae Alba, and after slightly vexed, put by slow fire heating, fried dry in pot, taking-up cools and namely obtains Radix Paeoniae Alba.Nature and flavor are bitter, acid, be slightly cold; Enter liver, spleen two warp, there is the effects such as nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing receipts antiperspirant, cure mainly the breast abdomen pain over the hypochondriac region, dysentery stomachache, spontaneous sweating, fever due to yin deficiency, menoxenia, metrorrhagia, the inferior disease of band.
Radix Angelicae Sinensis, nature and flavor are pungent, sweet, warm; Enter liver, the heart, spleen channel; The effects such as having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation; Cure mainly the diseases such as blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.
Radix Saposhnikoviae, acrid in the mouth, sweet; Slightly warm in nature; Enter bladder, liver, spleen channel; There is expelling pathogenic wind from the body surface, removing damp and stopping pain, the effects such as soothing the liver spasmolytic, killing parasites for relieving itching; Cure mainly affection of exogenous wind-cold, headache stiffness of the nape, dizzy dusk be puckery, anemofrigid-damp arthralgia, joint are ached, stomachache is had loose bowels, discharging fresh blood stool, broken damaging the spleen and stomach wind, measles difficult saturating, rubella pruritus, skin infection from the beginning of etc. disease.
Gypsum Fibrosum, nature and flavor are sweet, pungent, Great Cold; Return lung meridian, stomach warp; There is clearing away heat-fire, the effect such as relieving restlessness is quenched the thirst, heat-clearing and toxic substances removing; Cure mainly fever caused by exogenous pathogenic factors, high hot excessive thirst, dyspnea and cough due to lung-heat, the high Sheng of stomach-fire, calentura high fever do not move back, vexed coma, delirium are gone mad, thirsty and dry pharynx, lung-heat dyspnea with rapid respiration, heatstroke spontaneous perspiration, stomach-fire headache, toothache due to stomach-fire, hyperactivity of toxic heat, send out speckle dermexanthesis, aphtha of the mouth and tongue, ulcer sores, burst do not close up, the disease such as the burning hot wound of soup.
Radix Glycyrrhizae, nature and flavor are sweet, flat; Enter spleen, stomach, lung meridian; Have and the effects such as middle emergency, lung moistening, removing toxic substances; Control the diseases such as weakness of the spleen and stomach, lack of appetite, stomachache loose stool, overstrain heating, consumptive lung disease cough, cardiopalmus, infantile convulsion, laryngopharynx swelling and pain, peptic ulcer, ulcer sores, solution poison of drug and alimentary toxicosis.In the present invention, Radix Glycyrrhizae is as making medicine, can coordinating the actions of various ingredients in a prescription.
Drug component of the present invention and consumption few through inventor's long-term clinical application and carried out groping in a large number, adjust after sum up and draw.Usually, each component can obtain better curative effect when following dosage.
The important using method of the present invention is conventional decocting, oral after obtaining water preparation.Certainly, also oral liquid, pill or other dosage form can be made as required.
According to the infective use of this medicine in recent years, added up 89 routine patient with gout use this medicine after treatment situation.Wherein asymptomatic hyperuricemia 9 example, experimental study 32 example, tophus and chronic gout arthritis 48 example.Taking this medicine after three months, treatment group total effective rate is 96.7%, wherein cure rate 60%, obvious effective rate 26.7%, effective percentage 10%.
So-called recovery from illness refers to gout transference cure, and without recurrence.What is called is effective refers to that symptom alleviates, and what is called effectively refers to that subjective symptoms takes a turn for the better.
Compared with prior art, the present invention adopts treating both the principal and secondary aspects of a disease, by blood circulation promoting and dispersing pathogen accumulation, clearing away heat and eliminating dampness, starts with from spleen kidney, makes purine metabolism in body be excited and strengthen, and makes it to return to homergy level comprehensively.For the alleviating pain and detumescence rapidly of energy during gout acute attack, evident in efficacy, and without any side effects, after drug withdrawal, blood uric acid not easily rebounds, and prevents, in urate deposition joint and excess of the kidney matter, having good therapeutic effect to gout, and side effect is less, easily accepted by patient.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is described in further detail.
Preparation example 1
Preparation example 2
Preparation example 3
Case report:
1, Huang, man, 65 years old, height 165 centimetres, body weight 80 kilograms, psychentonia, hyperphagia, tired, excessive drinking, there was damage in joint.Suddenly, joint has an intense pain onset, occurs Hong Zhong inflammation heat after one hour, and tenderness and action restriction, about disappear gradually through a few days or several weeks, joint motion and profile thereof can be recovered.Be diagnosed as experimental study.
Take preparation example continuously to cure after 1 three months, within 3 years so far, pass by without recurrence, and take process and after curing, all find no side effect generation.
2, Liu, man, 48 years old, height 172 centimetres, body weight 86 kilograms.Surfeit rich and fatty diet at ordinary times, retention of damp-heat in the interior, diseases caused by exogenous pathogenic factor ailment said due to cold or exposure, invasion and attack meridians, QI and blood can not be unimpeded; Be apt to occur in female toe and Plantar toe joint, secondary is other joint of foot and ankle, hands, wrist, knee joint, elbow joint.Be diagnosed as chronic gout arthritis.Blood test, the uric acid concentration in blood is higher; X-ray checks, the osteoepiphyseal portion near articular surface has round defect.
Take preparation example continuously to cure after 1 three months, so far without recurrence, and take process and after curing, all find no side effect generation.
3, Wang, female, 52 years old, height 158 centimetres, body weight 75 kilograms, started acute pain occurs evening, and patient's pain from dream is waken up, and serious red and swollen heat pain phenomenon appears in joint, simultaneously with fever symptoms.Be diagnosed as experimental study.
Take preparation example continuously to cure after 2 three months, take again preparation example 1 one months.So far 3 years in the past, without recurrence, and takes process and all find no side effect generation after curing.
4, grandson, female 55 years old, height 165 centimetres, body weight 69 kilograms.Chronic gout arthritis, doctor trained in Western medicine checks that the uric acid concentration in blood is higher, and foot joint is out of shape, and wears footwear difficulty.Be diagnosed as tophus and chronic gout arthritis.
Take preparation example 3 three months, red, swollen, hot, the pain in joint disappear, and can wear footwear; Continue to take after two months, gout transference cure.

Claims (2)

1. treat a Chinese medicine composition for gout, it is characterized in that being made up of following weight component:
2. the Chinese medicine composition for the treatment of gout according to claim 1, is characterized in that being made up of following weight component:
CN201410058353.7A 2014-02-20 2014-02-20 A kind of Chinese medicine composition for the treatment of gout Expired - Fee Related CN103751642B (en)

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CN105434578A (en) * 2015-12-22 2016-03-30 刘可 Traditional Chinese medicine ointment for treating gout as well as preparation method and application of traditional Chinese medicine ointment

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102526275A (en) * 2011-12-29 2012-07-04 关秀敏 Pharmaceutical for curing gout and preparation method thereof
CN102652810A (en) * 2012-04-12 2012-09-05 王伟 Traditional Chinese medicine composition for treating gout and preparation method of traditional Chinese medicine composition

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102526275A (en) * 2011-12-29 2012-07-04 关秀敏 Pharmaceutical for curing gout and preparation method thereof
CN102652810A (en) * 2012-04-12 2012-09-05 王伟 Traditional Chinese medicine composition for treating gout and preparation method of traditional Chinese medicine composition

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