CN106668634A - Capsule medicine for treating rheumatoid arthritis, and preparation method of capsule medicine - Google Patents

Abstract

The invention belongs to the field of traditional Chinese medicine preparations, aiming at providing a capsule medicine for treating rheumatoid arthritis according to the know mechanism of the rheumatoid arthritis of traditional Chinese medicine. The capsule medicine is prepared from the following components in parts by mass: 30-100g of radix angelicae pubescentis, 30-100g of radix angelicae dahuricae, 100-260g of rhizoma et radix notopterygii, 80-160g of Chinese angelica, 50-120g of safflower, 50-120g of rhizoma chuanxiong, 50-120g of fructus chaenomelis, 20-60g of cortex cinnamomi, 100-150g of radix aconiti lateralis preparata, 80-160g of radix saposhnikoviae, 90-160g of herba lycopodii, 50-160g of frankincense, 50-200g of myrrh, 90-350g of semen coicis, 15-60g of cassia twig, 100-200g of white paeony root, 60-160g of cortex eucommiae, 150-260g of caulis spatholobi and 60-160g of radix achyranthis bidentatae. The medicine provided by the invention is a traditional Chinese medicine formula which can treat both symptoms and root causes.

Description

A kind of capsule medicine and preparation method for treating rheumatoid arthritiss

Technical field

It is special the invention belongs to field of traditional Chinese, and in particular to a kind of capsule medicine for treating rheumatoid arthritiss It is not the field of the capsule medicine and preparation method used for patient with rheumatoid arthritis.

Background technology

Rheumatoid arthritiss are a kind of systemic diseases based on joint synovitis disease, and often there is whole body morbidity early stage Symptom, such as heating, fatigue, diet is depressed, whole body discomfort, and severe patient can be simultaneously with anemia, clinical symptoms：Both hands refer to, double The Minor articulus such as toe, wrist, ankle are fallen ill first, and ankylosises occurs in daystart, and chemical examination rheumatoid factor (RF) is positive；To middle evening Phase, arthralgia exacerbates, and swelling, place is harder, and the large joints such as elbow, shoulder, knee joint, hip, severe patient are gradually involved in morning stiffness time lengthening, joint There is subluxation of joint and deformity, patient activity is limited, life to be difficult to take care of oneself.

Chinese pathology confirms that the basic pathological changes of primary disease are synovitis, acute stage performance exudative process and cell leaching Profit, synovial membrane lower floor thin vessels expansion, interstitial edema, chronic phase performance synovial membrane is thickening, forms many fine hair sample projections, dashes forward to joint Intracavity, and articular cartilage and subchondral sclerotin are immersed, the pathological changes beyond joint also have rheumatoid subcutaneous nodule and rheumatoid Vasculitiss etc., synovitis and vasculitiss cause joint long pain unbearably.

So, with regard to how to find it is a kind of can effectively treatment rheumatoid arthritiss medicine, be those skilled in the art urgently Problem to be resolved.

The content of the invention

With the continuous development of China's Chinese medicine, in treatment rheumatoid arthritiss, people gradually appreciate The advantage of Rheumatoid Arthritis with Traditional Chinese Medicine, and advantage, the pin such as over the course for the treatment of good effect, instant effect, toxic and side effects are little Present situation to existing western medical treatment rheumatoid arthritiss, it is to provide one kind to treat rheumatoid joint that the purpose of the present invention is Scorching capsule medicine, to solve patient with rheumatoid arthritis restorative problem early.The medicine is with common Medicine is raw material, by selecting rational medicine and mass parts ratio, can the above-mentioned rheumatoid arthritiss of effectively treatment.

To reach the purpose of foregoing invention, the technical solution adopted in the present invention is：One kind is provided and treats rheumatoid pass The scorching capsule medicine of section and preparation method, it is characterised in that each component of the medicine and its mass parts are than as follows：

30~100g of Radix Angelicae Pubescentiss, 30~100g of the Radix Angelicae Dahuricae, 100~260g of Rhizoma Et Radix Notopterygii, 80~160g of Radix Angelicae Sinensis, 50~120g of Flos Carthami, Rhizoma Chuanxiong 50 ~120g, 50~120g of Fructus Chaenomeliss, 20~60g of Cortex Cinnamomi, 100~150g of Radix Aconiti Lateralis Preparata, 80~160g of Radix Saposhnikoviae, 90~160g of Herba Lycopodii, 50~160g of Olibanum, 50~200g of Myrrha, 90~350g of Semen Coiciss, 15~60g of Ramulus Cinnamomi, 100~200g of the Radix Paeoniae Alba, the Cortex Eucommiae 60~ 160g, 150~260g of Caulis Spatholobi, 60~160g of Radix Achyranthis Bidentatae.

A kind of capsule medicine and preparation method for treating rheumatoid arthritiss, it is characterised in that the medicine it is each Individual component and its mass parts are than as follows：

40~90g of Radix Angelicae Pubescentiss, 40~90g of the Radix Angelicae Dahuricae, 115~230g of Rhizoma Et Radix Notopterygii, 90~140g of Radix Angelicae Sinensis, 60~105g of Flos Carthami, Rhizoma Chuanxiong 60~ 105g, 60~105g of Fructus Chaenomeliss, 30~50g of Cortex Cinnamomi, 115~130g of Radix Aconiti Lateralis Preparata, 90~140g of Radix Saposhnikoviae, 100~140g of Herba Lycopodii, breast 60~140g of perfume, 60~170g of Myrrha, 100~300g of Semen Coiciss, 20~50g of Ramulus Cinnamomi, 115~170g of the Radix Paeoniae Alba, the Cortex Eucommiae 70~ 140g, 170~230g of Caulis Spatholobi, 70~140g of Radix Achyranthis Bidentatae.

A kind of capsule medicine and preparation method for treating rheumatoid arthritiss, it is characterised in that " the optimal side Each component of the medicine of case " and its mass parts are than as follows：

Radix Angelicae Pubescentiss 80g, Radix Angelicae Dahuricae 80g, Rhizoma Et Radix Notopterygii 200g, Radix Angelicae Sinensis 120g, Flos Carthami 95g, Rhizoma Chuanxiong 95g, Fructus Chaenomeliss 95g, Cortex Cinnamomi 45g, Radix Aconiti Lateralis Preparata 115g, Radix Saposhnikoviae 120g, Herba Lycopodii 120g, Olibanum 120g, Myrrha 150g, Semen Coiciss 260g, Ramulus Cinnamomi 45g, Radix Paeoniae Alba 150g, the Cortex Eucommiae 120g, Caulis Spatholobi 200g, Radix Achyranthis Bidentatae 120g.

A kind of capsule medicine and preparation method for treating rheumatoid arthritiss, it is characterised in that methods described includes Following steps are prepared from：

A, above-mentioned raw materials Chinese medicine is picked after impurity, dust and drying, be ground into superfine end according to mass parts ratio stand-by；

B, the method that Chinese medicine capsules are prepared according to tradition, after ground superfine myrrh thing is sieved, are put in medicine device and mix Uniformly, then it is prepared into capsule（The sealed rear total length of its capsule be 23.3mm, medicated powder capacity 0.4~0.5g/ grains）, it is bottled close Envelope.

A kind of capsule medicine and preparation method for treating rheumatoid arthritiss, it is characterised in that the instructions of taking For：By the capsule medicine for preparing twice a day to take, service once sooner or later, dosage 2g（4）/ time, taking medicine after meal.15 It is a course for the treatment of, and 2~3 courses for the treatment of of taking medicine, symptom disappears, and disease obtains recovery from illness.

Each raw material Chinese medicine in prescription of the present invention has detailed note in Chinese Pharmacopoeia, Chinese dictionary and China's book on Chinese herbal medicine Carry.The present invention is raw material from most common of which Chinese medicine, gives full play to the pharmacological effect of each component：

Radix Angelicae Pubescentiss, nature and flavor：Pungent, bitter, tepor, the effect of with expelling wind and removing dampness, numbness relieving and pain relieving,

For treating anemofrigid-damp arthralgia, lumbocrural pain, few the moon volt wind headache；

The Radix Angelicae Dahuricae, nature and flavor：It is acrid in the mouth, warm in nature, with expelling wind and removing dampness, it is logical steal pain relieving, detumescence and apocenosis the effect of, for treatment flu head Bitterly, supraorbital bone pain, toothache, nasal obstruction, nasal sinusitis, domination of damp pathogen chronic diarrhea, women leucorrhea, ulcer sores, venom；

Rhizoma Et Radix Notopterygii, nature and flavor：Arduous, temperature, the effect of with scattered exterior cold, wind-damp dispelling, sharp joint, for treating cold, headache nothing Antiperspirant, anemofrigid-damp arthralgia, stiffness of the nape muscular contracture, joint ache, edema due to wind pathogen edema, skin sore；

Radix Angelicae Sinensis, nature and flavor：Warm in nature, sweet in the mouth is pungent, the effect of with benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturize laxation, for treat blood deficiency, Shallow complexion, dizziness palpitaition, blood deficiency have the stagnant menoxenia of the stasis of blood, amenorrhea, dysmenorrhea, deficient cold type stomachache, coronary heart disease heart strand concurrently Bitterly, rheumatic arthralgia, traumatic injury；

Flos Carthami, nature and flavor：It is acrid in the mouth, warm in nature, with promoting blood circulation can Jing, stasis-dispelling and pain-killing the effect of, for treating amenorrhea, dysmenorrhea, the stasis of blood in puerperal The diseases such as resistance stomachache, the pained lump in the abdomen of dysfunction of the urinary bladder, traumatic injury, arthralgia, middle windage yaw are completed, macule；

Rhizoma Chuanxiong, nature and flavor：Pungent, temperature, the effect of with activating QI to alleviate the depression, wet method wind-dryness, promoting blood circulation and stopping pain, for treating air-cooled headache rotation Dizzy, hypochondriac pain abdomen pain, arthralgia due to cold clonic spasm of the muscle, amenorrhea, difficult labour, postpartum stagnation block pain, ulcer sores, menoxenia, abdominal mass stomachache, chest side of body thorn Bitterly, tumbling and swelling, rheumatic arthralgia；

Fructus Chaenomeliss, nature and flavor：Warm in nature, sour in the mouth, have functions that to help digestion, anthelmintic, heat clearing away, wind-dispelling, for having a stomachache, dyspepsia, lung-heat Dry cough, galactostasiss, eczema, parasitic disease, trick spasm pain；

Cortex Cinnamomi, nature and flavor：Pungent, sweet, heat, the effect of with mends fire supporing yang, let the fire back to its origin, dispersing cold for relieving pain, warming the meridian and promoting blood circulation, for treating Insufficiency of kidney-YANG, gate of vitality's fire aversion to cold and cold limbs, soreness of the waist and knees, impotence and seminal emission, dysuria or frequency, dyspnea with rapid and short breath of losing heart, edema oliguria are all Card, life

Door fire declines, Gui Yuan, floating YANG, refusing yang and heat in the upper and cold in the lower, flushed complexion cold foot, dizziness and tinnitus, dispute be rotten broken for fire, spleen kidney deficiency Cold, coldness and pain in the epigastrium, decreased food intake loose stool, lumbago due to renal deficiency, arthralgia due to cold-dampnes, colic of cold type pain, uterus cold infertile, dysmenorrhea amenorrhea, the stagnant abdomen of the stasis of blood in puerperal Bitterly, carbuncle of yin nature multiple abscess or deficiency and coldness carbuncle and ulcer difficulty in discharging of pus or do not hold back after bursting；

Radix Aconiti Lateralis Preparata, nature and flavor：Pungent, sweet, big heat, it is poisonous, with recuperating depleted YANG and rescuing the patient from collapse, mends fire supporing yang, by wind-cold damp pathogen the effect of, for controlling Treat YANG-depletion collapse, cold weak pulse of limb, sexual impotence, cold womb, trusted subordinate's crymodynia, cold of insufficiency type vomiting and diarrhea, cold sensation of the genitalia oedema, deficiency of yang diseases caused by external factors, arthralgia due to cold-dampnes, the moon Cellulitis skin infection；

Radix Saposhnikoviae, nature and flavor：Acrid in the mouth, sweet, slightly warm in nature, with expelling pathogenic wind from the body surface, removing dampness to relieve pain, spasmolytic, it is antipruritic the effect of, it is outer for treating Sense wind and cold, headache general pain, rheumatic arthralgia, joint is ached, stomachache are had loose bowels, discharging fresh blood stool, tetanus, rubella itch, skin infection from the beginning of；

Herba Lycopodii, nature and flavor：Bitter, pungent, temperature, it is nontoxic, with expelling wind and cold, dehumidification swelling, relaxing muscles and tendons to promote blood circulation, cough-relieving, removing toxic substances the effect of, For treating anemofrigid-damp arthralgia, joint aches, skin numbness, tetraparesis, edema, traumatic injury, jaundice, cough, skin infection, bleb Rash, scald；

Olibanum, nature and flavor：Arduous, temperature, has functions that regulating qi and activating blood, analgesic therapy, chases after poison, for coagulation of QI-blood, trusted subordinate's pain, ulcerative carbuncle Toxic swelling, traumatic injury, dysmenorrhea, postnatal blood stasis twinge etc.；

Myrrha, nature and flavor：It is bitter, flat, the effect of with eliminating stasis to stop pain, externally used detumescence granulation promoting, for treating swell and ache for falling dozen extravasated blood, carbuncle Swell and ache, all pains of chest and abdomen, external controls the open sore part and the disease such as do not restrain long；

Semen Coiciss, nature and flavor：It is sweet in the mouth, light, cool in nature, with favourable water penetration is wet, invigorating the spleen to arrest diarrhea, eliminating impediment, evacuation of pus, the work(of detoxicating and resolving stagnation of pathogens Effect, for treating the diseases such as edema, tinea pedis, dysuria, diarrhea due to hypofunction of the spleen, arthralgia chiefly caused by damp pathogen contracture, lung abscess, acute appendicitis, wart, cancerous protuberance；

Ramulus Cinnamomi, nature and flavor：It is pungent, sweet, warm in nature, the effect of with expelling cold and relieving exterior syndrome, promoting the flow of QI-blood by warming the meridian, activating YANG and prormoting functioning of QI, for treating wind and cold table Card, arthralgia due to cold-dampnes, extreme cold of the limbs, amenorrhea dysmenorrhea, mass in the abdomen caking, the thoracic obstruction, cardiopalmus, phlegm retention, dysuria；

The Radix Paeoniae Alba, nature and flavor：It is picric acid, cool, with nourishing blood to suppress the hyperactive liver, it is slow in pain relieving, yin fluid astringing receive antiperspirant the effect of, for treating chest and abdomen side of body rib pain Bitterly, diarrhea dysentery abdominal pain, spontaneous sweating, fever due to yin deficiency, menoxenia, metrorrhagia, with inferior disease；

The Cortex Eucommiae, nature and flavor：It is sweet, micro-pungent, warm in nature, with invigorating the liver and kidney, bone and muscle strengthening, it is antiabortive the effect of, for treating spinal column ache, sun Flaccidity, frequent micturition, dribbling urination, rheumatic arthralgia, frequent fetal movement, habitual abortion；

Caulis Spatholobi, nature and flavor：Bitter sweet, temperature, with promoting blood circulation, relaxing muscles and tendons the effect of, for treating soreness of waist and knee joint, paralysis and numbness, menstruation not Adjust；

Radix Achyranthis Bidentatae, nature and flavor：It is bitter, sour, mild-natured, with invigorating the liver and kidney, bone and muscle strengthening, promoting blood circulation to restore menstrual flow, draw enemy state（Fire) descending, inducing diuresis for treating stranguria syndrome it Effect, for treat soreness of waist and knee joint, flaccidity and weakness of the lower limbs, amenorrhea due to stagnation of blood, dysmenorrhea, abdominal pain due to blood stasis in puerperal, note of the ancient Chinese abdominal mass, retention of placenta, pyretic stranguria, Stranguria with blood, traumatic injury, Carbuncle swells dislikes sore, laryngopharynx swelling and pain.

Medicine of the present invention is, based on the principle of Rheumatoid Arthritis with Traditional Chinese Medicine, to recognize from pharmacological action and mechanism of action For：With regard to rheumatoid arthritiss, each raw material herbal medicine efficacy in medicine provided by the present invention is played altogether, is had very well to above-mentioned disease Therapeutic effect.

Specific embodiment

A kind of Chinese medicine formula that the present invention is aiming at the treatment of above-mentioned rheumatoid arthritiss and proposes, using the formula The medicine effect of preparation is good, instant effect, is the Chinese prescription of a treating both the principal and secondary aspects of a disease, is particularly suitable for Clinical practice.With reference to this The specific embodiment of invention is described in further detail：

Embodiment 1：

A kind of capsule medicine for treating rheumatoid arthritiss, it is characterised in that each component of the medicine and its quality Part is than as follows：

Radix Angelicae Pubescentiss 80g, Radix Angelicae Dahuricae 80g, Rhizoma Et Radix Notopterygii 200g, Radix Angelicae Sinensis 120g, Flos Carthami 95g, Rhizoma Chuanxiong 95g, Fructus Chaenomeliss 95g, Cortex Cinnamomi 45g, Radix Aconiti Lateralis Preparata 115g, Radix Saposhnikoviae 120g, Herba Lycopodii 120g, Olibanum 120g, Myrrha 150g, Semen Coiciss 260g, Ramulus Cinnamomi 45g, Radix Paeoniae Alba 150g, the Cortex Eucommiae 120g, Caulis Spatholobi 200g, Radix Achyranthis Bidentatae 120g.

Embodiment 2：

A kind of capsule medicine for treating rheumatoid arthritiss, it is characterised in that each component of the medicine and its quality Part is than as follows：

It is Radix Angelicae Pubescentiss 90g, Radix Angelicae Dahuricae 90g, Rhizoma Et Radix Notopterygii 230g, Radix Angelicae Sinensis 140g, Flos Carthami 105g, Rhizoma Chuanxiong 105g, Fructus Chaenomeliss 105g, Cortex Cinnamomi 50g, black attached Sub- 130g, Radix Saposhnikoviae 140g, Herba Lycopodii 140g, Olibanum 140g, Myrrha 170g, Semen Coiciss 300g, Ramulus Cinnamomi 50g, Radix Paeoniae Alba 170g, the Cortex Eucommiae 140g, Caulis Spatholobi 230g, Radix Achyranthis Bidentatae 140g.

Embodiment 3：

A kind of capsule medicine for treating rheumatoid arthritiss, it is characterised in that each component of the medicine and its quality Part is than as follows：

It is Radix Angelicae Pubescentiss 100g, Radix Angelicae Dahuricae 100g, Rhizoma Et Radix Notopterygii 260g, Radix Angelicae Sinensis 160g, Flos Carthami 120g, Rhizoma Chuanxiong 120g, Fructus Chaenomeliss 120g, Cortex Cinnamomi 60g, black Radix Aconiti Lateralis Preparata 150g, Radix Saposhnikoviae 160g, Herba Lycopodii 160g, Olibanum 160g, Myrrha 200g, Semen Coiciss 350g, Ramulus Cinnamomi 60g, Radix Paeoniae Alba 200g, Du Secondary 160g, Caulis Spatholobi 260g, Radix Achyranthis Bidentatae 160g.

Model case

Jing clinical conditions patient with rheumatoid arthritis totally 770, the age is 486 of more than 52 years old, and only 284 are Less than 52 years old.635 fully recovered in 770 patients, effective 135, total effective rate is up to 100%.

Claims (3)

1. a kind of capsule medicine for treating rheumatoid arthritiss, it is characterised in that each component of the medicine and its matter Amount part is than as follows：

30~100g of Radix Angelicae Pubescentiss, 30~100g of the Radix Angelicae Dahuricae, 100~260g of Rhizoma Et Radix Notopterygii, 80~160g of Radix Angelicae Sinensis, 50~120g of Flos Carthami, Rhizoma Chuanxiong 50 ~120g, 50~120g of Fructus Chaenomeliss, 20~60g of Cortex Cinnamomi, 100~150g of Radix Aconiti Lateralis Preparata, 80~160g of Radix Saposhnikoviae, 90~160g of Herba Lycopodii, 50~160g of Olibanum, 50~200g of Myrrha, 90~350g of Semen Coiciss, 15~60g of Ramulus Cinnamomi, 100~200g of the Radix Paeoniae Alba, the Cortex Eucommiae 60~ 160g, 150~260g of Caulis Spatholobi, 60~160g of Radix Achyranthis Bidentatae.

2. it is according to claim 1 treatment rheumatoid arthritiss capsule medicine, it is characterised in that the medicine Each component and its mass parts are than as follows：

40~90g of Radix Angelicae Pubescentiss, 40~90g of the Radix Angelicae Dahuricae, 115~230g of Rhizoma Et Radix Notopterygii, 90~140g of Radix Angelicae Sinensis, 60~105g of Flos Carthami, Rhizoma Chuanxiong 60~ 105g, 60~105g of Fructus Chaenomeliss, 30~50g of Cortex Cinnamomi, 115~130g of Radix Aconiti Lateralis Preparata, 90~140g of Radix Saposhnikoviae, 100~140g of Herba Lycopodii, breast 60~140g of perfume, 60~170g of Myrrha, 100~300g of Semen Coiciss, 20~50g of Ramulus Cinnamomi, 115~170g of the Radix Paeoniae Alba, the Cortex Eucommiae 70~ 140g, 170~230g of Caulis Spatholobi, 70~140g of Radix Achyranthis Bidentatae.

3. the capsule medicine of the treatment rheumatoid arthritiss according to claim 1 to 2, it is characterised in that the medicine Each component of thing and its mass parts are than as follows：

Radix Angelicae Pubescentiss 80g, Radix Angelicae Dahuricae 80g, Rhizoma Et Radix Notopterygii 200g, Radix Angelicae Sinensis 120g, Flos Carthami 95g, Rhizoma Chuanxiong 95g, Fructus Chaenomeliss 95g, Cortex Cinnamomi 45g, Radix Aconiti Lateralis Preparata 115g, Radix Saposhnikoviae 120g, Herba Lycopodii 120g, Olibanum 120g, Myrrha 150g, Semen Coiciss 260g, Ramulus Cinnamomi 45g, Radix Paeoniae Alba 150g, the Cortex Eucommiae 120g, Caulis Spatholobi 200g, Radix Achyranthis Bidentatae 120g.