CN101085338A - Traditional Chinese medicine preparation for curing uric acid nephritis - Google Patents
Traditional Chinese medicine preparation for curing uric acid nephritis Download PDFInfo
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- CN101085338A CN101085338A CN 200710117898 CN200710117898A CN101085338A CN 101085338 A CN101085338 A CN 101085338A CN 200710117898 CN200710117898 CN 200710117898 CN 200710117898 A CN200710117898 A CN 200710117898A CN 101085338 A CN101085338 A CN 101085338A
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Abstract
The invention relates to a Chinese medicinal combination for treating nephritis which is prepared from more than ten kinds of Chinese medicinal herbs including large-leaf gentian root, achyranthes and cyathula root, rhizoma zedoariae and corydalis ambigua.
Description
Technical field
The present invention relates to treat the Chinese medicine preparation of uric acid nephritis, is that a kind of uric acid nephritis for the treatment of is the Chinese medicine preparation of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Urate nephropathy is meant the renal damage of urate deposition due to renal medulla, a matter or the far-end collecting tubule.Clinical in soreness of waist pain, polyuria, nocturia, or hematuria, urinary stone, or renal colic, oliguria anuria, or anemia, nausea and vomiting etc. are main clinical manifestation.And often with the outer symptom of kidneys such as redness and swelling of joints burning pain such as the sole of the foot, toe, knee joint, wrist, finger and heating.The concealment of primary disease onset is made slow progress, and eventually to chronic renal failure, also can sharply increase the weight of, and acute renal failure takes place.This onset of disease with extremities joint swell and ache, lumbago, hematuria, stranguria be main performance, being developed to the later stage is feature with oliguria, vomiting, edema.Because the raising of national life level and the variation of dietary structure are increased the incidence rate of hyperuricemia, urate nephropathy year by year.Though hyperuricemia patient only has 10%～20% clinical kidney performance is arranged, and it is reported that there is kidney damage in various degree in nearly all patient on pathology, many patients often develop into renal failure just changes the prescription on individual diagnosis of kidney section.Urate nephropathy comes into one's own day by day in recent years, and traditional Chinese medical science research urate nephropathy has obtained very gratifying progress.Tcm clinical practice medicine typing scheme is gradually improved, and the advantage of performance Chinese medicine all obtains curative effect preferably, has not only alleviated the toxic and side effects of Western medicine, and has improved clinical symptoms, reduces blood uric acid, consolidates aspect such as curative effect and has shown bigger advantage, can take for a long time.The traditional Chinese medical science is divided disease type Coryza Treated by Syndrome Differentiation clinically, obtains very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine preparation for the treatment of uric acid nephritis.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by the following weight proportion raw material:
1.0～4 parts of 1.5～6 parts of Radix Codonopsis of 1.5～6 portions of Radix Gentianae Macrophyllae of Radix Cyathulae
0.1～2 part of 1.0～4 parts of rhizoma sparganic of 1.5～6 parts of Rhizoma Curcumae of Rhizoma Corydalis
0.1～2 part of 1.0～4 parts of Radix Angelicae Pubescentis of 1.0～4 parts of Rhizoma Atractylodis of Herba Leonuri
0.1～2 part of 1.0～4 parts of Ramulus Cinnamomi of 1.0～4 portions of Cortex Phellodendris of Rhizoma Atractylodis Macrocephalae (parched).
The weight proportion of each raw material of optimization formula of the present invention is:
1.5～2.5 parts of 2.5～3.5 parts of Radix Codonopsis of 2.5～3.5 portions of Radix Gentianae Macrophyllae of Radix Cyathulae
0.5～1.5 part of 1.5～2.5 parts of rhizoma sparganic of 2.5～3.5 parts of Rhizoma Curcumae of Rhizoma Corydalis
0.5～1.5 part of 1.5～2.5 parts of Radix Angelicae Pubescentis of 1.5～2.5 parts of Rhizoma Atractylodis of Herba Leonuri
0.5～1.5 part of 1.5～2.5 parts of Ramulus Cinnamomi of 1.5～2.5 portions of Cortex Phellodendris of Rhizoma Atractylodis Macrocephalae (parched).
The weight proportion of each raw material of optimum formula of the present invention is:
2 parts of 3 parts of Radix Codonopsis of 3 portions of Radix Gentianae Macrophyllae of Radix Cyathulae
1 part of 2 parts of rhizoma sparganic of 3 parts of Rhizoma Curcumae of Rhizoma Corydalis
1 part of 2 parts of Radix Angelicae Pubescentis of 2 parts of Rhizoma Atractylodis of Herba Leonuri
1 part of 2 parts of Ramulus Cinnamomi of 2 portions of Cortex Phellodendris of Rhizoma Atractylodis Macrocephalae (parched).
Drug action mechanism among the present invention is as follows:
Sweet, the little hardship of the Radix Cyathulae property of medicine, flat.Return liver, kidney channel.Has blood circulation promoting and blood stasis dispelling, the effect of expelling wind and removing dampness.Can treat the blood stasis amenorrhea, difficult labour, retention of placenta, postnatal blood stasis stomachache, pyretic stranguria, stranguria caused by urinary stone, dysmenorrhea, rheumatism lumbocrural pain, traumatic injury etc.(the 301st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Gentianae Macrophyllae property of medicine hardship, suffering are slightly cold.Return stomach, liver, gallbladder meridian.Has wind-damp dispelling, clearind deficient heat, the effect of jaundice eliminating.Can treat rheumatic arthralgia, muscles and bones contracture, hands and feet caused by paralysis, osteopyrexia and fever, children's's infantile malnutrition with fever, jaundice due to damp-heat etc.(the 2469th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Rhizoma Corydalis property of medicine suffering, hardship, temperature.GUIXIN, liver, spleen channel.Has promoting blood circulation to remove blood stasis, the effect of promoting the circulation of QI to relieve pain.Can treat obstruction of qi in the chest and cardialgia, epigastric pain, lumbago, colicky, dysmenorrhea, amenorrhea ， mass in the abdomen, the stasis of blood stagnated and suffered from abdominal pain traumatic injury etc. puerperal.(the 1261st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Herba Leonuri property of medicine suffering, hardship are slightly cold.Return liver, kidney, pericardium channel.Has promoting blood flow to regulate menstruation, inducing diuresis to remove edema, the effect of heat-clearing and toxic substances removing.Can treat menoxenia, amenorrhea, vaginal bleeding during pregnancy difficult labour, retention of placenta, puerperal blood faints, abdominal pain due to blood stasis, traumatic injury, dysuria, edema, carbuncle skin infection etc.(the 2697th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Rhizoma Atractylodis Macrocephalae (parched) hardship, sweet, temperature.Return spleen, stomach warp.Has invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive effect.Can treat the weak of deficiency-weakness of spleen-QI, lack of appetite abdominal distention is had loose bowels, constipation, the dysuria of fluid-retention stagnating in the interior, edema, dizziness due to fluid-retention, cold-damp numbness, general pain, spontaneous sweating due to deficiency of QI, frequent fetal movement etc.(the 945th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).Rhizoma Curcumae nature and flavor hardship, suffering, temperature.Return liver, spleen channel.Have the circulation of qi promoting removing blood stasis with potent drugs, the removing food stagnancy pain relieving is changed poly-eliminating mass, the effect of antiearly pregnancy.Can treat that trusted subordinate's distending pain, lump in the abdomen, dyspepsia do not disappear, hepatosplenomegaly, abdominal pain due to blood stasis, amenorrhea due to stagnation of blood, cervical erosion, traumatic injury have a pain etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 995th page).
Rhizoma Atractylodis property of medicine suffering, hardship, temperature.Return spleen, stomach, Liver Channel.Have drying damp and strengthening spleen, wind-damp dispelling, the effect that makes eye bright.Can treat the spleen and stomach being stranded by dampness, the asthenia drowsiness, feeling of stuffiness in chest abdominal distention, inappetence, vomiting is had loose bowels, phlegm retention, damp-edema, the exterior syndrome folder is wet, a heavy sensation of the body pain, arthromyodynia domination of damp pathogen, podomere are ached and are being weighed, and flaccidity is sprained, nyctalopia etc.(the 1485th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Cortex Phellodendri property of medicine hardship, cold.Return kidney, bladder, large intestine channel.Has heat clearing and damp drying, the effect of eliminating fire and detoxication.Can treat hygropyretic dysentery, have loose bowels, jaundice, nocturnal emission, stranguria with turbid discharge, leukorrhagia, hectic fever due to YIN-deficiency consumptive fever ， Wei Bi, and aphtha of the mouth and tongue, conjunctival congestion and swelling pain, skin sore, skin eczema etc.(the 2823rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Codonopsis property of medicine is sweet, and is flat.Return spleen, lung meridian.Has strengthening the spleen and tonifying the lung, the effect of supplementing QI for promoting the production of body fluid.Can treat weakness of the spleen and stomach, anorexia and loose stool, limbs fatigue, the deficiency of the lung is breathed with cough, the cold sweating of breathing hard, deficiency of both QI and blood etc.(the 2579th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Rhizoma sparganic nature and flavor suffering, hardship, flat.Return liver, spleen channel.Has removing blood stasis, circulation of qi promoting, removing food stagnancy analgesic effect.Can treat lump in the abdomen, coagulation of QI-blood, trusted subordinate's pain, the food stagnation distending pain, the side of body expands down painful, amenorrhea, dysmenorrhea, puerperal abdominalgia with blood stasis, traumatic injury, skin ulcer is swollen hard, hepatosplenomegaly etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 69th page).
Radix Angelicae Pubescentis property of medicine hardship, suffering, tepor.Return kidney, urinary bladder channel.Has expelling wind and dampness, the effect of dispersing cold for relieving pain.Can treat anemofrigid-damp arthralgia, lumbocrural pain, headache toothache etc.(the 2389th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Ramulus Cinnamomi property of medicine suffering, sweet, temperature.Return bladder, the heart, lung meridian.Has expelling cold and relieving exterior syndrome, warming the meridian, the effect of activating yang.Can treat exterior syndrome due to wind-cold, arthralgia due to cold-dampnes, extreme cold of the limbs, amenorrhea dysmenorrhea ， mass in the abdomen caking, the thoracic obstruction, cardiopalmus, phlegm retention, dysuria etc.(the 2522nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Rhizoma Curcumae, Radix Gentianae Macrophyllae and Radix Cyathulae; With Rhizoma Atractylodis, Cortex Phellodendri, Herba Leonuri, Radix Codonopsis, Rhizoma Atractylodis Macrocephalae (parched) and Rhizoma Corydalis is ministerial drug; With rhizoma sparganic, Radix Angelicae Pubescentis and Ramulus Cinnamomi is adjuvant.All medicines are harmonious, and are total to the tool function of warming yang and gore removing, the effect of removing obstruction in the collateral to relieve pain.The treatment uric acid nephritis has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of Pharmacopoeia of People's Republic of China, utilizes the comprehensive function treatment uric acid nephritis of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat uric acid nephritis, and the prevention of uric acid nephritis is also had good effect, and the treatment uric acid nephritis has determined curative effect, has no side effect taking convenience, cheap characteristics.
For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment uric acid nephritis; Treatment uric acid nephritis patient 22 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Two months is a course of treatment, take continuously three the course of treatment observe the curative effect.10 examples of fully recovering account for 45.45%, and 9 examples that take a turn for the better account for 40.91%, and invalid 3 examples account for 13.64%, and total effective rate reaches 86.36%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
The embodiment decoction takes by weighing raw material by following weight:
2 parts of 3 parts of Radix Codonopsis of 3 portions of Radix Gentianae Macrophyllae of Radix Cyathulae
1 part of 2 parts of rhizoma sparganic of 3 parts of Rhizoma Curcumae of Rhizoma Corydalis
1 part of 2 parts of Radix Angelicae Pubescentis of 2 parts of Rhizoma Atractylodis of Herba Leonuri
1 part of 2 parts of Ramulus Cinnamomi of 2 portions of Cortex Phellodendris of Rhizoma Atractylodis Macrocephalae (parched).
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5～2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1～1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment uric acid nephritis that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Two months is a course of treatment.
Claims (3)
1, the Chinese medicine preparation of treatment uric acid nephritis is characterized in that it is made by the following weight proportion raw material:
1.0～4 parts of 1.5～6 parts of Radix Codonopsis of 1.5～6 portions of Radix Gentianae Macrophyllae of Radix Cyathulae
0.1～2 part of 1.0～4 parts of rhizoma sparganic of 1.5～6 parts of Rhizoma Curcumae of Rhizoma Corydalis
0.1～2 part of 1.0～4 parts of Radix Angelicae Pubescentis of 1.0～4 parts of Rhizoma Atractylodis of Herba Leonuri
0.1～2 part of 1.0～4 parts of Ramulus Cinnamomi of 1.0～4 portions of Cortex Phellodendris of Rhizoma Atractylodis Macrocephalae (parched).
2, the Chinese medicine preparation of treatment uric acid nephritis according to claim 1, wherein the weight proportion of each raw material is:
1.5～2.5 parts of 2.5～3.5 parts of Radix Codonopsis of 2.5～3.5 portions of Radix Gentianae Macrophyllae of Radix Cyathulae
0.5～1.5 part of 1.5～2.5 parts of rhizoma sparganic of 2.5～3.5 parts of Rhizoma Curcumae of Rhizoma Corydalis
0.5～1.5 part of 1.5～2.5 parts of Radix Angelicae Pubescentis of 1.5～2.5 parts of Rhizoma Atractylodis of Herba Leonuri
0.5～1.5 part of 1.5～2.5 parts of Ramulus Cinnamomi of 1.5～2.5 portions of Cortex Phellodendris of Rhizoma Atractylodis Macrocephalae (parched).
3, the Chinese medicine preparation of treatment uric acid nephritis according to claim 1, wherein the weight proportion of each raw material is:
2 parts of 3 parts of Radix Codonopsis of 3 portions of Radix Gentianae Macrophyllae of Radix Cyathulae
1 part of 2 parts of rhizoma sparganic of 3 parts of Rhizoma Curcumae of Rhizoma Corydalis
1 part of 2 parts of Radix Angelicae Pubescentis of 2 parts of Rhizoma Atractylodis of Herba Leonuri
1 part of 2 parts of Ramulus Cinnamomi of 2 portions of Cortex Phellodendris of Rhizoma Atractylodis Macrocephalae (parched).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200710117898 CN101085338A (en) | 2007-06-26 | 2007-06-26 | Traditional Chinese medicine preparation for curing uric acid nephritis |
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| Application Number | Priority Date | Filing Date | Title |
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| CN 200710117898 CN101085338A (en) | 2007-06-26 | 2007-06-26 | Traditional Chinese medicine preparation for curing uric acid nephritis |
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| CN101085338A true CN101085338A (en) | 2007-12-12 |
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| CN 200710117898 Pending CN101085338A (en) | 2007-06-26 | 2007-06-26 | Traditional Chinese medicine preparation for curing uric acid nephritis |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103432279A (en) * | 2013-08-07 | 2013-12-11 | 许春桂 | Method for preparing soaking agent for preventing and treating gout with decoction dregs and product |
| CN106266463A (en) * | 2016-11-08 | 2017-01-04 | 四圣网络科技（上海）有限公司 | A kind of Chinese medicine composition for treating hyperuricemia and application thereof |
-
2007
- 2007-06-26 CN CN 200710117898 patent/CN101085338A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103432279A (en) * | 2013-08-07 | 2013-12-11 | 许春桂 | Method for preparing soaking agent for preventing and treating gout with decoction dregs and product |
| CN103432279B (en) * | 2013-08-07 | 2015-05-27 | 许春桂 | Method for preparing soaking agent for preventing and treating gout with decoction dregs and product |
| CN106266463A (en) * | 2016-11-08 | 2017-01-04 | 四圣网络科技（上海）有限公司 | A kind of Chinese medicine composition for treating hyperuricemia and application thereof |
| CN106266463B (en) * | 2016-11-08 | 2020-04-28 | 四圣网络科技（上海）有限公司 | Traditional Chinese medicine composition for treating hyperuricemia and application thereof |
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Open date: 20071212 |