CN102698135B - Traditional Chinese medicine composition for treating hypertension, hyperglycemia and hyperlipidemia, and application thereof - Google Patents

Traditional Chinese medicine composition for treating hypertension, hyperglycemia and hyperlipidemia, and application thereof Download PDF

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CN102698135B
CN102698135B CN 201210160595 CN201210160595A CN102698135B CN 102698135 B CN102698135 B CN 102698135B CN 201210160595 CN201210160595 CN 201210160595 CN 201210160595 A CN201210160595 A CN 201210160595A CN 102698135 B CN102698135 B CN 102698135B
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chinese medicine
medicine composition
semen
treatment
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CN102698135A (en
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文波
冯医博
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Abstract

The invention discloses a traditional Chinese medicine composition for treating hypertension, hyperglycemia and hyperlipidemia, and application of the traditional Chinese medicine composition. On the one hand, the traditional Chinese medicine composition for treating hypertension, hyperglycemia and hyperlipidemia comprises the following raw medicines by weight: 8-12 parts of adlay, 8-12 parts of corn stigma, 8-12 parts of plantain seed, 5-7 parts of alum processed pinellia and 8-12 parts of fructus aurantii. On the other hand, the traditional Chinese medicine composition for treating hypertension, hyperglycemia and hyperlipidemia is used for preparing pharmaceutical preparations for treating hypertension, hyperglycemia and hyperlipidemia as active substances. According to the invention, natural Chinese herbal medicines are used as raw materials, so that the traditional Chinese medicine composition is used securely and conveniently, is featured with significantly curative effect, and is capable of reducing blood sugar, blood pressure and blood fat.

Description

A kind of Chinese medicine composition and application thereof that is used for the treatment of three-hypers disease
Technical field
The present invention relates to a kind of Chinese medicine composition and application thereof, relate in particular to a kind of Chinese medicine composition and application thereof that is used for the treatment of three-hypers disease.
Background technology
Hypertension (hypertensive disease) is one of three-hypers disease, and it is a kind of chronic disease take the lasting rising of arteriotony as main manifestations, often causes the pathological changes of the vitals such as the heart, brain, kidney and corresponding consequence occurs.
The blood pressure standard of using according to World Health Organization (WHO) (Who) suggestion is: all normal adult systolic pressures should be less than or equal to 140mmHg(18.6kPa), diastolic pressure is less than or equal to 90mmHg(12kPa).That is systolic pressure is at 141-159mmHg(18.9-21.2kPa) between, diastolic pressure is at 91-94mmHg(12.1-12.5kPa) between, be borderline hypertension.During office hypertension, repeatedly Measure blood pressure has the meansigma methods of double diastolic pressure at least at 90mmHg(12.0kPa) or abovely just can be diagnosed as hypertension.Only a hypertension person still can not make a definite diagnosis, but needs follow-up observation.Hypertension is modal cardiovascular diseases, is the great public health problem in the global range.Chinese residents nutrition in 2004 and Health Situation survey result show that China 18 years old and above prevalence of hypertension rate are 18.8%, estimate that national number of patients surpasses 1.6 hundred million.Compared with 1991, prevalence rises 31%, and number of patients increases about more than 7 000 ten thousand people.
1998, China's cerebrovascular occupied the second of urbanite's cause of death, ranks first in the rural area.The whole nation is annual dead to surpass 1,000,000, and the patient of survival is about 5,000,000~6,000,000, wherein leaves deformity in various degree more than 75%, has caused white elephant for individual, family and society.And the Major Risk Factors of apoplexy is hypertension.Simultaneously, hypertension or the fuse cord of various diseases can make the onset risk of the diseases such as coronary heart disease, heart failure and kidney disease increase.Because the part hyperpietic there is no obvious clinical symptoms, hypertension be otherwise known as " the invisible killer " of human health.
For a long time, treatment hypertension must be used oral medicines in a large number for a long time, generally just there are shortcomings such as dosage is large, onset is slow, side effect is large, especially in morning, it is hypertensive patient's drug effect decay the most dangerous the time, although therefore a lot of hypertensive patients adhere to taking medicine, but still appearance " sudden death in morning ".Doctor and patient is all wished effective in cure good, drug effect is long, consumption is little, expense is low medicine for this reason.
Three-hypers disease also comprises hyperlipidemia, hyperglycemia.At present the effect to the medicine of three-hypers disease treatment is comparatively general, is difficult to effective blood sugar lowering, blood pressure lowering, blood fat reducing.
Summary of the invention
First purpose of the present invention is to provide a kind of Chinese medicine composition that is used for the treatment of three-hypers disease.
The objective of the invention is to realize by following technical measures: a kind of Chinese medicine composition that is used for the treatment of three-hypers disease is comprised of the crude drug of following weight portion:
Semen Coicis 8-12 part Stigma Maydis 8-12 part Semen Plantaginis 8-12 part
Rhizoma Pinelliae 5-7 part Fructus Aurantii 8-12 part.
Semen Coicis has the spleen invigorating eliminating dampness by diuresis among the present invention, the effect of eliminating impediment antidiarrheal; Stigma Maydis have expel the heat-evil treating stranguria, the effect of suppressing the hyperactive liver function of gallbladder promoting; Semen Plantaginis has the effect of clearing away heat and promoting diuresis, eliminating dampness by diuresis antidiarrheal; Rhizoma Pinelliae has drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, the effect of dissolving lump and resolving mass; Fructus Aurantii cures mainly septum pectorale feeling of fullness, distending pain over the hypochondrium, accumulation of food in the stomach and intes tine due to indigestion and distension and fullness in the abdomen, more than a few flavor medicines effect of playing altogether the timid expectorant of dampness removing, make phlegm-damp be difficult to be detained effectively blood sugar lowering, blood pressure lowering, blood fat reducing.
A kind of Chinese medicine composition that is used for the treatment of three-hypers disease is comprised of the crude drug of following weight portion:
Semen Coicis 8-12 part Stigma Maydis 8-12 part Semen Plantaginis 8-12 part
Rhizoma Pinelliae 5-7 part Fructus Aurantii 8-12 part Hirudo 8-12 part.Hirudo collateral dredging assisting in opening blood vessels passage.
A kind of Chinese medicine composition that is used for the treatment of three-hypers disease is comprised of the crude drug of following weight portion:
Semen Coicis 8-12 part Stigma Maydis 8-12 part Semen Plantaginis 8-12 part
Rhizoma Pinelliae 5-7 part Fructus Aurantii 8-12 part Hirudo 8-12 part
Semen Cassiae 16-24 part Flos Chrysanthemi Indici 8-12 part Radix Achyranthis Bidentatae 8-12 part Margarita 8-12 part.
Make and play sedative action take Semen Cassiae Flos Chrysanthemi Indici, Radix Achyranthis Bidentatae and Margarita as assistant, so that the effect that the present invention has simultaneously the dampness removing collateral dredging and calms the nerves, the treatment of hyperlipidemia, hypertension, hyperglycemia is had better curative effect.
Second purpose of the present invention be to provide the above-mentioned Chinese medicine composition that is used for the treatment of three-hypers disease as active substance for the preparation of the application in the pharmaceutical preparation for the treatment of three-hypers disease.
Chinese medicine composition of the present invention can be prepared into by the active substance that existing conventional Chinese medicine preparation extracts Chinese medicine composition the pharmaceutical preparation for the treatment of three-hypers disease, such as oral formulations.Wherein, oral formulations comprises tablet, capsule, granule and powder.
The present invention compared with prior art has following beneficial effect:
The present invention uses safety, convenient take natural Chinese herbal medicine as raw material.Medicine can be rapidly with endovascular triglyceride, cholesterol, low-density lipoprotein Pseudobulbus Bletillae (Rhizoma Bletillae) heavy-metal residual thing after entering human body, took 1 day, the patient can begin to get rid of toxin, headache uncomfortable in chest, and weak night sweat is alleviated, sleep takes a turn for the better, and medicine is adsorbate lactone speckle at short notice, with its thorough disintegrate, be melted into molecularity, excretes smoothly, dredge narrow or occluding vascular, fast quick-recovery blood vessel elasticity.Simultaneously, rubbish and free radical in the blood of human body are eliminated, and circulation improves, and unobstructed blood vessel is without hindrance, guarantee the supply of heart and brain blood oxygen, and the flight against senium of human body function is strengthened greatly, worry that no longer the heart and brain sudden death occurs.
Below in conjunction with clinical trial effect of the present invention is set forth:
Get hyperlipidemia, hypertension, hyperglycemia 100 examples, man's 45 examples wherein, the woman was 55 example ages, all more than 45 years old, administration time 1-3 months, effective percentage 87 percent, cure rate 86 percent has the not yet disconnected medicine of 14 examples.
[0020]1. grandsons for example, the man, 56 years old, build was fat, suffered from hyperlipidemia, hypertension and hyperglycemia for many years, took Western medicine and kept, can not be from medicine, through the radical cure in three months of this preparation.
Example 2. Lu, the woman, 46 years old, for hyperlipidemia, hypertension, through western medicines in treatment, still can not take this preparation from medicine through hospital's inspection, cured in two months, follow up a case by regular visits to not recurrence in 2 years.
Example 3. Hao, man, 40 years old, suffer from hypertension, hyperlipidemia and hyperglycemia, Morning Blood Pressure is 100/140 millimetres of mercury, cooperates the treatment by Chinese herbs poor effect through Western medicine, and it is obviously weak that health appears in patient, listless, visual deterioration was cured the bimester of taking Chinese medicine composition of the present invention on the 15th, followed up a case by regular visits to and did not recur January, Morning Blood Pressure is 80/120 millimetres of mercury, and health is obviously improved.
Example 4. models, the woman, 66 years old, be diagnosed as hypertension and cerebral infarction, hospitalization did not change the left side numbness of hands and feet in 20 days, took and visitd aspirin tablet and Chinese patent medicine kendir pressure-reducing, noon, blood pressure was 100/152 millimetres of mercury, take behind the Chinese medicine composition of the present invention and to follow up a case by regular visits in 3 months, the numbness of hands and feet sense disappears entirely, and afternoon, blood pressure was 78/118 millimetres of mercury.
Example 5. Xiongs, man, 65 years old, vascular hypertension 5 years, take Western medicine nifedipine slow releasing tablet, blood pressure is 94/146 millimetres of mercury behind the medicine, the dizzy symptom of head occurs, take that blood pressure is 78/128 millimetres of mercury behind the Chinese medicine composition of the present invention, cured in 2 months and not follow up a case by regular visits to recurrence, head is uncomfortable to disappear.
The specific embodiment
Below in conjunction with embodiment the present invention is set forth, yet protection scope of the present invention is not only to be confined to following examples.The person of an ordinary skill in the technical field all can realize purpose of the present invention according to content disclosed by the invention.
Embodiment one
Prescription:8 parts of 5 parts of Fructus Aurantiis of 8 parts of Rhizoma Pinelliae of 8 portions of Semen Plantaginiss of 8 parts of Stigma Maydis of Semen Coicis
8 parts of 8 parts of Margaritas of 8 parts of Radix Achyranthis Bidentataes of 16 parts of Flos Chrysanthemi Indicis of 8 parts of Semen Cassiaes of Hirudo
Preparation method:Take by weighing each crude drug by above proportioning, grind to form 80 order powder, the zero capsule of packing into obtains capsule.Above-mentioned medicine also can be made into tablet, granule and powder etc. and does not affect protection scope of the present invention according to routine techniques.
Embodiment two
Different from embodiment one is:
Prescription:12 parts of 7 parts of Fructus Aurantiis of 12 parts of Rhizoma Pinelliae of 12 portions of Semen Plantaginiss of 12 parts of Stigma Maydis of Semen Coicis
12 parts of 12 parts of Margaritas of 12 parts of Radix Achyranthis Bidentataes of 24 parts of Flos Chrysanthemi Indicis of 12 parts of Semen Cassiaes of Hirudo.
Embodiment three
Different from embodiment one is:
Prescription:11 parts of 6 parts of Fructus Aurantiis of 9 parts of Rhizoma Pinelliae of 10 portions of Semen Plantaginiss of 9 parts of Stigma Maydis of Semen Coicis
9 parts of 11 parts of Margaritas of 11 parts of Radix Achyranthis Bidentataes of 20 parts of Flos Chrysanthemi Indicis of 9 parts of Semen Cassiaes of Hirudo.
Embodiment four
Different from embodiment one is:
Prescription:9 parts of 5 parts of Fructus Aurantiis of 11 parts of Rhizoma Pinelliae of 11 portions of Semen Plantaginiss of 10 parts of Stigma Maydis of Semen Coicis
10 parts of 10 parts of Margaritas of 11 parts of Radix Achyranthis Bidentataes of 22 parts of Flos Chrysanthemi Indicis of 10 parts of Semen Cassiaes of Hirudo.
Above-described embodiment is preferred embodiment of the present invention; but embodiments of the invention are not restricted to the described embodiments; and other any do not deviate from change, the modification done under spirit of the present invention and the principle, substitutes, combination, simplify; all should be the substitute mode of equivalence, be included within protection scope of the present invention.

Claims (10)

1. a Chinese medicine composition that is used for the treatment of three-hypers disease is characterized in that, is comprised of the crude drug of following weight portion:
Semen Coicis 8-12 part Stigma Maydis 8-12 part Semen Plantaginis 8-12 part
Rhizoma Pinelliae 5-7 part Fructus Aurantii 8-12 part.
2. a Chinese medicine composition that is used for the treatment of three-hypers disease is characterized in that, is comprised of the crude drug of following weight portion:
Semen Coicis 8-12 part Stigma Maydis 8-12 part Semen Plantaginis 8-12 part
Rhizoma Pinelliae 5-7 part Fructus Aurantii 8-12 part Hirudo 8-12 part.
3. a Chinese medicine composition that is used for the treatment of three-hypers disease is characterized in that, is comprised of the crude drug of following weight portion:
Semen Coicis 8-12 part Stigma Maydis 8-12 part Semen Plantaginis 8-12 part
Rhizoma Pinelliae 5-7 part Fructus Aurantii 8-12 part Hirudo 8-12 part
Semen Cassiae 16-24 part Flos Chrysanthemi Indici 8-12 part Radix Achyranthis Bidentatae 8-12 part Margarita 8-12 part.
4. the Chinese medicine composition that is used for the treatment of three-hypers disease according to claim 3 is characterized in that,
8 parts of 5 parts of Fructus Aurantiis of 8 parts of Rhizoma Pinelliae of 8 portions of Semen Plantaginiss of 8 parts of Stigma Maydis of Semen Coicis
8 parts of 8 parts of Margaritas of 8 parts of Radix Achyranthis Bidentataes of 16 parts of Flos Chrysanthemi Indicis of 8 parts of Semen Cassiaes of Hirudo.
5. the Chinese medicine composition that is used for the treatment of three-hypers disease according to claim 3 is characterized in that,
12 parts of 7 parts of Fructus Aurantiis of 12 parts of Rhizoma Pinelliae of 12 portions of Semen Plantaginiss of 12 parts of Stigma Maydis of Semen Coicis
12 parts of 12 parts of Margaritas of 12 parts of Radix Achyranthis Bidentataes of 24 parts of Flos Chrysanthemi Indicis of 12 parts of Semen Cassiaes of Hirudo.
6. the Chinese medicine composition that is used for the treatment of three-hypers disease according to claim 3 is characterized in that,
11 parts of 6 parts of Fructus Aurantiis of 9 parts of Rhizoma Pinelliae of 10 portions of Semen Plantaginiss of 9 parts of Stigma Maydis of Semen Coicis
9 parts of 11 parts of Margaritas of 11 parts of Radix Achyranthis Bidentataes of 20 parts of Flos Chrysanthemi Indicis of 9 parts of Semen Cassiaes of Hirudo.
7. the Chinese medicine composition that is used for the treatment of three-hypers disease according to claim 3 is characterized in that,
9 parts of 5 parts of Fructus Aurantiis of 11 parts of Rhizoma Pinelliae of 11 portions of Semen Plantaginiss of 10 parts of Stigma Maydis of Semen Coicis
10 parts of 10 parts of Margaritas of 11 parts of Radix Achyranthis Bidentataes of 22 parts of Flos Chrysanthemi Indicis of 10 parts of Semen Cassiaes of Hirudo.
The Chinese medicine composition that is used for the treatment of three-hypers disease claimed in claim 1 as active substance for the preparation of the application in the pharmaceutical preparation for the treatment of three-hypers.
9. the Chinese medicine composition that is used for the treatment of three-hypers disease according to claim 8 for the preparation of the application in the pharmaceutical preparation for the treatment of three-hypers, is characterized in that described pharmaceutical preparation is oral formulations as active substance.
10. the Chinese medicine composition that is used for the treatment of three-hypers disease according to claim 9 for the preparation of the application in the pharmaceutical preparation for the treatment of three-hypers, is characterized in that described oral formulations comprises tablet, capsule, granule and powder as active substance.
CN 201210160595 2012-05-22 2012-05-22 Traditional Chinese medicine composition for treating hypertension, hyperglycemia and hyperlipidemia, and application thereof Expired - Fee Related CN102698135B (en)

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CN105641536A (en) * 2016-04-08 2016-06-08 北京御心堂生物科技股份有限公司 Composition for improving immunity and treating three-high diseases as well as decoction and preparation method

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1879802A (en) * 2006-05-17 2006-12-20 吴守仓 Nutritious Chinese medicinal product for replenishing liver and kidney, resisting senility, decreasing blood fat, blood sugar and blood pressure and method for preparing same
CN101804141A (en) * 2010-05-07 2010-08-18 张银川 Chinese medicine compound for preventing and curing hypertension, hyperlipidemia, hyperglycemia and complications thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1879802A (en) * 2006-05-17 2006-12-20 吴守仓 Nutritious Chinese medicinal product for replenishing liver and kidney, resisting senility, decreasing blood fat, blood sugar and blood pressure and method for preparing same
CN101804141A (en) * 2010-05-07 2010-08-18 张银川 Chinese medicine compound for preventing and curing hypertension, hyperlipidemia, hyperglycemia and complications thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
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