CN107549554B - Fruit juice fermented beverage with beautifying and freckle removing functions and preparation method thereof - Google Patents
Fruit juice fermented beverage with beautifying and freckle removing functions and preparation method thereof Download PDFInfo
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- CN107549554B CN107549554B CN201710723138.8A CN201710723138A CN107549554B CN 107549554 B CN107549554 B CN 107549554B CN 201710723138 A CN201710723138 A CN 201710723138A CN 107549554 B CN107549554 B CN 107549554B
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- fruit juice
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- lactic acid
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Abstract
The invention discloses a fruit juice fermentation liquid with functions of beautifying and removing freckles, which is prepared by fermenting mulberries and hawthorn fruits through mixed lactic acid bacteria. The invention adopts the mixed strain of food-grade lactobacillus plantarum and lactobacillus fermentum as the fermentation strain to ferment and generate SOD enzyme and other nutrient substances, can comprehensively supplement SOD in human bodies, can enhance the metabolism of cells, has obvious functions of beautifying and removing freckles, and can also enhance the resistance of human bodies; the problem of bacterial and viral pollution can not occur in the fermentation process of the adopted food-grade fermentation strain, so that the safety problem of the fermentation liquor is solved; the mulberry and the hawthorn with health care function are added, so that a new way is provided for the comprehensive utilization of the mulberry and the hawthorn, and the economic value is greatly improved.
Description
Technical Field
The invention relates to the technical field of health-care drinks, in particular to a fruit juice fermented drink with functions of beautifying and removing freckles and a preparation method thereof.
Background
Chloasma (choleasma) belongs to the categories of black speck, liver speckle, face dust and butterfly speck in the traditional Chinese medicine, is a common dermatosis with brown or black pigmentation damage on the face caused by skin melanin increase, and is one of difficult and complicated diseases of dermatology. It is mainly characterized by that the limited light brown or brown spot is appeared on forehead, eyebrow, cheek and upper lip, its boundary is clear, surface is smooth, and its distribution is symmetrical, so that it is frequently seen in pregnant woman and woman with irregular menstrual blood, and the ratio of female patient to male patient is about 9: 1. The disease is in a chronic process, has a persistent course and is lingering and difficult to heal, the beauty of a patient is seriously affected, and a lot of troubles and pains are brought to the spirit and life of the patient. The incidence of the disease is high, and in recent years, the incidence of the disease tends to increase year by year due to the influence of various factors, and the number of patients is more and more. With the change of living environment and the improvement of living standard of people, chloasma is becoming one of the hot spots of common attention and research in the medical and cosmetic fields at present.
The pathogenesis and mechanism of chloasma are complex, and whether the chloasma is related to various factors such as oral contraceptives, genetic factors, oxygen free radical accumulation, trace element content abnormality, liver function abnormality and the like is not very clear at present. Modern medicine considers that the medicine is related to endocrine dyscrasia, pregnancy, uterine soft nest diseases and other factors. The traditional Chinese medicine considers that the disease is closely related to the three viscera of liver, spleen and kidney, and is caused by qi stagnation and blood stasis and failure of qi and blood to nourish the face due to liver depression transforming into fire, liver and kidney deficiency or spleen failure in transportation. At present, most researches suggest that chloasma is caused by that the activity of melanocytes at the skin damage part of a chloasma patient is enhanced, melanin and melanosomes are increased, and then stains are expressed, and in a pathological state, dermal macrophages can phagocytose and drip into dermal melanosomes, or are deposited on the upper layer of dermis, or are degraded in cells, and a part of chloasma is transferred by lymph. The production and excretion of pigment are unbalanced, and the excess accumulates in the epidermal cells, resulting in pigmentation. There are two pathways for melanin excretion: one is excretion from the kidney and the other is excretion from the skin, i.e. melanin is transferred to keratin, migrates to the stratum corneum with epidermal growth, and finally is shed with periodical renewal of the stratum corneum. The modern medicine for treating chloasma has the main principles of inhibiting the activity of melanocyte, inhibiting the synthesis of melanin, removing the generated melanin, destroying melanin particles, applying a light-shading agent with a light-proof effect and the like. Currently, there are several main treatments: (1) the vitamin C is administered orally or intravenously, and is used in combination with vitamin E to prevent oxidation of melanin metabolism and inhibit melanin formation; (2) the topical hydroquinone cream can inhibit formation of melanin granule and increase its degradation, inhibit synthesis of DNA and RNA of melanocyte, has no influence on melanocyte, and has certain therapeutic effect in combination with broad-spectrum sunscreen for treating skin type and mixed type chloasma, or topical retinoic acid cream can inhibit tyrosinase activity of melanoma cell cultured in vitro, prevent melanin from transferring to stratum corneum cell, simultaneously reduce keratinization, and increase drug penetration. Although the clinical western medicines have a certain curative effect on treating chloasma, the effect is often poor, side effects of different degrees exist, and serious complications are easily caused after long-term application. However, the traditional Chinese medicine has a complete treatment theoretical system and rich clinical experience in the aspect of treating chloasma and has the advantage of unique function of integrally adjusting viscera, so the traditional Chinese medicine has wide prospect in the aspect of treating chloasma.
The melanin is formed by generating dopa from colorless tyrosine under the action of tyrosinase, and the dopa is changed into dopaquinone under the action of tyrosinase, and then through a series of oxidation processes. Normally, after melanin formation, a part of melanin is decomposed and discharged from the body through the kidney, and another part of melanin is exfoliated by exfoliation of the epidermis. However, if the activity of tyrosine is enhanced and melanin is increased, the increased melanin cannot be discharged out of the body due to the slow metabolism, and the melanin is accumulated on the face to form spots. The spots are the reaction of dysfunction of internal organs, disharmony between qi and blood, stagnation of qi due to depression of the liver, stagnation of qi and blood stasis, poor circulation of qi, blood and body fluids, and endocrine disturbance on the face. The traditional Chinese medicine treats both principal and secondary aspects of the chloasma, treats the chloasma through the five internal organs, and achieves the purposes of removing freckles and beautifying by regulating qi, blood and body fluid to balance yin and yang, thereby preventing the chloasma from recurring.
At present, the external application medicine which takes biological antioxidants such as polyphenol, saponin and the like with oxidation resistance as main components is adopted for clinically treating chloasma, and has low cure rate, high recurrence rate, unobvious curative effect and inconvenient medication. Health care and treatment cannot be carried out by combining human intrinsic factors for regulating endocrine balance, promoting metabolism, resisting oxidation and eliminating free radicals with the principle of resisting fatigue.
At present, health-care food with freckle (such as black speck and chloasma) removing function, such as formulas reported in Chinese patent application CN200710065545.0 or CN 201110341598, are reported or on the market, and the formulas have complex components, at least more than 9 components and complex preparation process, are all traditional Chinese medicine components, are troublesome in decocting process and have poor taste.
In addition, there are some formulations for removing freckles, such as:
1. the formula is as follows: 20g of mother-of-pearl, 3 roses, 10 Chinese dates, 10 g of white chrysanthemum, loofah sponge, white muscardine silkworm and white poria, wherein each 10 g of the raw materials comprises the following components: cutting the above materials, putting into a pot, adding 3 bowls of clear water, decocting with slow fire to 1 bowl, and using: the decoction is taken 1 dose a day and 2 times, and the continuous taking is 10 days as 1 course of treatment, if effective, the decoction can be taken for a long time. The efficacy is as follows: clearing heat and expelling toxin, and beautifying and removing freckles: is suitable for butterfly rash.
2. The formula is as follows: 10 g of angelica, white peony root and eclipta alba respectively, 15g of prepared rhizome of rehmannia and dodder seed respectively, 12 g of glossy privet fruit and tuber fleeceflower root respectively, and 9g of medlar and donkey-hide gelatin (packaged separately and taken by 2 times) respectively. The preparation method comprises the following steps: cutting the above (except colla Corii Asini) materials, placing into a pan, adding 3-4 bowls of clear water, decocting with slow fire to 1 bowl, and using: decocting 1 dose daily with water 2 times, adding colla Corii Asini before administration, melting by heat, and administering for 3-6 months continuously, or administering for a long time. The efficacy is as follows: kidney purging fire, toxin expelling and spot removing remarks: it is suitable for chloasma.
3. The formula is as follows: oriental wormwood, serissa serissoide, selfheal, poria cocos (with black skin removed) each 12 g, white chrysanthemum, white muscardine silkworm, red white peony root, luffa each 9g, mother-of-pearl 20g, raw licorice root 3 g. The preparation method comprises the following steps: cutting the above materials, placing into a pot, adding 3-4 bowls of clear water, and decocting with slow fire to 1 bowl. The use method comprises the following steps: the medicine is decocted with water for 2 times 1 dose a day, and is continuously taken for 2 weeks for 1 course of treatment, if the effect is needed, the medicine is taken continuously until the cure is achieved, and the medicine can not be stopped in midway so as to avoid relapse. The efficacy is as follows: clear stagnated heat, expel internal toxicity and remove chloasma.
4. The formula is as follows: dangshen, szechuan lovage rhizome, dried rehmannia root, Indian buead and fried largehead atractylodes rhizome each 12 g, Chinese angelica and red paeony root each 15g, safflower and peach seed each 10 g, roasted astragalus root 18 g, 10 red dates and liquorice 6 g: cutting the above materials, placing into a pan, adding 4 bowls of clear water, and decocting with slow fire to 1 bowl. The use method comprises the following steps: the decoction is taken 1 dose a day and 2 times, 10 days is taken continuously as 1 course of treatment, and the effective patient should continue to take after 2 courses of treatment. The efficacy is as follows: tonify qi and blood, strengthen spleen and stomach, expel internal toxicity and remove brown spots.
5. The formula is as follows: 40 g of peach blossom, 50 g of waxgourd seed kernel and 30 g of orange peel. The preparation method comprises the following steps: baking the above materials, grinding into fine powder, and bottling. The use method comprises the following steps: the medicine is taken 3 times a day, 1 g each time, with warm wine after meals for 30 days continuously. The efficacy is as follows: promoting snow and removing blood stasis, and expelling toxin and removing freckles for remarks: is suitable for chloasma caused by qi stagnation, blood stasis and phlegm dampness.
The components of the formula are complex and all traditional Chinese medicine components, the decocting process is relatively troublesome, the taste is not good, and the effect is slight when a black spot patient takes the formula for one month.
Therefore, it is necessary to provide a spot-removing product which is simple to prepare, convenient to drink, good in taste, has the functions of beautifying and removing spots and also has other nutritional ingredients.
Disclosure of Invention
The invention provides a fruit juice fermentation broth which is prepared by inoculating a certain amount of lactobacillus plantarum and lactobacillus fermentum into a mixed pulp of mulberries and hawthorns, wherein the total mass of the inoculated mixed strains is 0.01-0.1% of the total mass of the mulberries and the hawthorns, uniformly stirring, fermenting for 6-8 weeks, and fermenting to generate nutrient substances. The food-grade fermentation strain is used, the problem of bacterial and viral pollution can not occur in the fermentation process, and the safety problem of the plant enzyme is solved. And the preparation method of the plant enzyme has short fermentation time, simple operation and low cost, and is beneficial to the industrial production of the method. Clinical tests prove that the plant enzyme provided by the invention has good effects of beautifying and removing freckles.
The invention aims to provide a fruit juice fermented beverage with functions of beautifying features and removing freckles and a preparation method thereof.
In order to achieve the purpose, the invention adopts the technical scheme that: the fruit juice fermentation liquor with the functions of beautifying and removing freckles is prepared by fermenting mulberries and hawthorn fruits through mixed lactic acid bacteria, wherein the mulberries and the hawthorn fruits are prepared in parts by weight: 10-20 parts of mulberry and 2-4 parts of hawthorn; the added mixed lactobacillus accounts for 0.01-0.1% of the total mass of the mulberries and the hawthorns.
The mulberry has the effects of improving blood supply of skin (including scalp), nourishing skin, whitening and tendering skin, blackening hair and the like, and can delay aging. The mulberry is a good fruit and good medicine for the middle-aged and the elderly to strengthen the body, beautify the face and resist aging. Mulberry has the functions of promoting the production of body fluid to quench thirst, promoting digestion, helping defecation and the like, and can promote gastric secretion, stimulate intestinal peristalsis and remove dryness-heat when being eaten in a proper amount. The mulberry is regarded by Chinese medicine as sweet and cold in nature and taste, and has the effects of tonifying liver and kidney, promoting fluid production, moistening intestines, blackening hair, improving eyesight and the like.
The mulberry contains a large amount of procyanidine and resveratrol, and the fruit cluster contains sugar tannic acid, malic acid, vitamin B1, vitamin B2, carotene and the like. The mulberry fruit beverage has the nutritional ingredients of 48 kcal per 100 g of mulberry fruit, 1.6 g of protein, 0.4 g of fat, 12.9 g of carbohydrate, 3.3 g of dietary fiber, 3 mg of vitamin A, 20 mg of carotene, 0.05 mg of riboflavin, 12.78 mg of vitamin E, 30 mg of calcium, 33 mg of phosphorus, 32 mg of potassium, 1.9 mg of sodium, 0.3 mg of iron, 0.25 mg of zinc, 6.5 mg of selenium, 0.06 mg of copper and 0.29 mg of manganese.
The fatty acid in Mori fructus has effects of decomposing fat, reducing blood lipid and preventing angiosclerosis; the mulberry contains hair blackening agent which can make hair black and bright; mulberry has the functions of improving skin, supplying blood to scalp, nourishing skin, whitening skin, blackening hair and the like, and can delay aging; mulberry has the function of immunity promotion and can prevent and resist cancer; mulberry mainly enters liver and kidney, so that the functions of nourishing yin and blood, promoting fluid production and moistening dryness are suitable for yin and blood deficiency of liver and kidney, body fluid deficiency, diabetes, intestinal dryness and other diseases; the mulberry can improve eyesight and relieve the symptoms of eye fatigue and dryness by frequent eating. Can be eaten by general people, and is particularly suitable for people with deficiency of liver, kidney and yin blood, teenagers with leukotrichia, weak body and habitual constipation.
The hawthorn mainly contains active ingredients such as lipase, flavonoid, organic acid and the like. The hawthorn can promote blood circulation and metabolism by promoting blood circulation and removing blood stasis, and is beneficial to the decomposition of melanin in vivo, so that the melanin cannot be precipitated to form color spots. Clinical reports show that the hawthorn powder can promote facial blood circulation, improve facial skin metabolism and gradually dissipate facial pigments by external application. Clinical application shows that the compound beautifying and spot removing preparation comprising haw can obtain satisfactory curative effect on chloasma.
The titrating acid of the juice fermentation liquor prepared by the invention is 15-20g/L, and the content of superoxide dismutase is 500-1000U/g.
Superoxide dismutase (SOD) is an active substance originated from living body, can eliminate harmful substances generated in the metabolism process of organism, continuously supplement SOD to human body, and has effects of resisting aging and oxidation, regulating endocrine system of human body, and improving immunity.
Preferably, the mixed lactic acid bacteria comprise lactobacillus plantarum and lactobacillus fermentum, the mass ratio of the lactobacillus plantarum to the lactobacillus fermentum is 1:0.8-1.5, and the concentrations of the lactobacillus plantarum and the lactobacillus fermentum are both 1.0 x 1011-1.5×1011cfu/g。
The invention also provides a fruit juice fermented beverage with the functions of beautifying and removing freckles, which comprises the fruit juice fermented liquid and auxiliary materials, wherein the components in parts by weight are as follows:
preferably, the water-soluble dietary fiber is polydextrose.
The juice fermentation liquor brewed by the modern biotechnology has double values of nourishing blood and beautifying. The fermentation liquid is prepared by inoculating natural juice of Mori fructus and fructus crataegi with Lactobacillus plantarum and Lactobacillus fermentum. The fruit juice fermentation liquid is an acidic fermentation liquid rich in SOD component. The juice fermentation broth can be added with collagen peptide, polydextrose (water soluble dietary fiber), xylitol, calcium lactate, nicotinic acid, and vitamin B6 to make into juice fermented beverage, which has effects of caring skin and removing speckle.
Collagen is a very important protein of the human body, and is mainly present in connective tissues. It has strong stretching ability, is the main component of ligament and muscle bond, and collagen is also the main component of extracellular matrix. It keeps the skin elastic, and aging of collagen causes wrinkles to appear on the skin.
Collagen is a biological high molecular substance, and is a white, opaque, unbranched fibrous protein. It can supplement nutrients required by each layer of skin, enhance collagen activity in skin, and has effects of moistening skin, delaying aging, caring skin, removing wrinkle, and nourishing hair.
Collagen is a nutrient substance which must be supplemented for delaying senility of a human body, accounts for more than 30 percent of total protein of the whole body of the human body, and about 3 kilograms of collagen exists in the body of an adult. It is widely present in skin, bone, muscle, cartilage, joint and hair tissues of human body, and plays a role in supporting, repairing and protecting, and collagen is mainly distributed in connective tissues of mammals, is very important for the formation of skin, blood vessels, bone, tendon, teeth and cartilage of animals and human bodies, and is the main material basis of the connective tissues. It is not exaggerated that collagen is the life support of all animals.
Collagen is the most prominent structure in the dermis layer of the skin, and the intact collagen structure affects the elasticity of the skin and helps the skin to support a three-dimensional space. When the collagen is reduced along with the aging, the supporting force of the dermis layer is weakened, the skin is damaged and sunken, wrinkles appear, the elasticity of a large area of the skin is reduced, and the skin is obviously aged.
According to peptide nutriology (textbook of department of Nutrition and food sanitation of the public health college of Beijing university), collagen with molecular weight below 1000 Dalton is called collagen peptide, can be directly absorbed by human body without decomposition, and has obvious effect in oral absorption and external skin care. This is currently the most mature and effective collagen supplement method, but it is noted that it is preferable to be pure natural small collagen peptide (molecular weight less than 1000 daltons) without additives, so as to enter the dermis layer really to help repair and restore the skin and collagen layer.
Polydextrose is a special carbohydrate with low calorie, no sugar, low glycemic index, and is characterized by water-soluble dietary fiber and prebiotics. Polydextrose can form a film in small intestine, and can wrap part of food fat, adsorb bile acid, cholesterol, etc., increase excretion of the above substances, and regulate blood lipid.
Calcium lactate regulates vascular resistance, inhibits fat absorption, and increases the ratio of high-density lipoprotein to low-density lipoprotein; compared with the inorganic calcium commonly used in the market, the calcium carbonate has better solubility and absorption rate.
Nicotinic acid is also called vitamin B3, or vitamin PP, and is converted into nicotinamide in human body, and the nicotinamide is a component of coenzyme I and coenzyme II, is involved in lipid metabolism in vivo, can inhibit triglyceride lipase activity, and can reduce low density lipoprotein and very low density lipoprotein level and increase high density lipoprotein level from many aspects; promote the excretion of neutral cholesterol through intestinal tract, and slowly reduce the content of cholesterol and low density lipoprotein.
Vitamin B6(Vitamin B6), also known as pyridoxine, which includes pyridoxine, pyridoxal and pyridoxamine, exists in vivo in the form of phosphate, is a water-soluble Vitamin, participates in the conversion of homocysteine to methionine, has the effect of reducing chronic diseases, mild hyperhomocysteinemia is considered as a possible risk factor for vascular diseases, and intervention of Vitamin B6 can reduce plasma homocysteine content.
The fruit juice fermentation liquor is also an effective method for reducing cholesterol after being eaten for a long time, and the fermentation liquor obtained by fermenting the mulberries has stronger effects of beautifying and removing freckles, because the mulberries are rich in various phenolic compounds which are all high-efficiency SOD antioxidants, and can protect low-density lipoprotein in blood from oxidative damage, thereby reducing the occurrence of arteriosclerosis. The fermentation liquor is rich in nutrient components, has good nutritive value, and has the effects of relieving fatigue, regulating blood sugar and lipid metabolism, resisting oxidation and the like.
The invention also provides a preparation method of the fruit juice fermented beverage, which comprises the following steps:
1) cleaning the mulberries and the hawthorns, centrifuging to remove water, and pulping in a pulping machine to obtain mixed pulp;
2) conveying the mixed slurry obtained in the step 1) into a fermentation tank through a sterile pipeline, inoculating a mixed lactic acid bacterium, uniformly stirring, and fermenting for 6-8 weeks to obtain a juice fermentation broth;
3) sequentially adding collagen peptide, water-soluble dietary fiber, xylitol, calcium lactate, nicotinic acid and vitamin B6 into the juice fermentation broth obtained in the step 2), mixing, subpackaging into 30ml small bottles, and sterilizing at 121 ℃ for 20min to obtain the juice fermented beverage.
Preferably, the mass of the mixed lactobacillus inoculated in the step 2) is 0.01-0.1% of the mass sum of the mulberry and the hawthorn.
Preferably, the mixed lactic acid bacteria comprise lactobacillus plantarum and lactobacillus fermentum, the mass ratio of the lactobacillus plantarum to the lactobacillus fermentum is 1:0.8-1.5, and the concentration of the lactobacillus plantarum to the lactobacillus fermentum is 1.0 x 1011-1.5×1011cfu/g。
Preferably, the fermentation conditions in step 2) are controlled as follows: setting the temperature to be 30-32 ℃ within 1 week after the mixed lactic acid bacteria are inoculated; starting at 2 weeks after inoculation of the mixed lactic acid bacteria strain, the temperature was set at 26-30 ℃.
The invention adopts food-grade fermentation strains, can directly purchase the bacterial powder from the market, stores the bacterial powder in a refrigeration house before use, and moves the bacterial powder to the room temperature from the refrigeration house 12 hours before use.
The invention also provides the application of the juice fermentation liquor in the health-care food for assisting in beautifying and removing freckles, and the juice fermentation liquor is added into the health-care food for assisting in beautifying and removing freckles as an active ingredient. For example, it can be added to food, such as cookies, cakes, or to drinks, etc.
Compared with the prior art, the invention has the following advantages and effects: 1) the invention adopts the mixed strain of food-grade lactobacillus plantarum and lactobacillus fermentum as the fermentation strain to ferment and generate SOD enzyme and other nutrient substances, can comprehensively supplement SOD in human bodies, can enhance the metabolism of cells, has obvious functions of beautifying and removing freckles, and can also enhance the resistance of human bodies; 2) the problem of bacterial and viral pollution can not occur in the fermentation process of the adopted food-grade fermentation strain, so that the safety problem of the fermentation liquor is solved; 3) the mulberry and the hawthorn with health care function are added, so that the problems that the mulberry and the hawthorn deep processing leavening are insufficient in health care function and high added value products are difficult to form are solved, a new way is provided for comprehensive utilization of the mulberry and the hawthorn, and the economic value is greatly improved.
Detailed Description
The technical solution of the present invention is further explained with reference to the specific embodiments.
Example 1
The fruit juice fermentation broth with the functions of beautifying and removing freckles is prepared by fermenting 10 parts by mass of mulberry and 2 parts by mass of hawthorn through mixed lactic acid bacteria, wherein the mass of the added mixed lactic acid bacteria is 0.02% of the total mass of the mulberry and the hawthorn, and the mixed lactic acid bacteria comprise lactobacillus plantarum and lactobacillus fermentum in a mass ratio of 1: 0.8.
The prepared juice fermentation liquor with the functions of beautifying and removing freckles has 17g/L of titrating acid and 900U/g of content of superoxide dismutase.
A fruit juice fermented beverage with functions of beautifying and removing freckles comprises a fruit juice fermentation liquid and auxiliary materials, wherein the components in parts by weight are as follows:
the preparation method of the fruit juice fermented beverage comprises the following steps:
1) cleaning the mulberries and the hawthorns, centrifuging to remove water, and pulping in a pulping machine to obtain mixed pulp;
2) conveying the mixed serous fluid obtained in the step 1) into a fermentation tank through an aseptic pipeline, inoculating a mixed lactic acid bacteria strain, wherein the mixed lactic acid bacteria strain comprises lactobacillus plantarum and lactobacillus fermentum, the mass ratio of the lactobacillus plantarum to the lactobacillus fermentum is 1:0.8, the total mass of the mixed bacteria strain is 0.02 percent of the total mass of the mulberries and the hawthorns, and the concentrations of the lactobacillus plantarum and the lactobacillus fermentum are 1 multiplied by 1011cfu/mL, stirring uniformly, and fermenting for 7 weeks to obtain a juice fermentation broth; wherein the conditions of the fermentation process are controlled as follows: setting the temperature to be 30 ℃ within 1 week after the mixed lactic acid bacteria are inoculated; starting at 2 weeks after inoculation of the mixed lactic acid bacteria strain, the temperature was set at 26 ℃.
3) Sequentially adding collagen peptide, polydextrose, xylitol, calcium lactate, nicotinic acid and vitamin B6 into the juice fermentation broth obtained in the step 2), fully mixing, subpackaging into 30ml vials, and sterilizing at 121 ℃ for 20min to obtain the juice fermented beverage.
Example 2
The fruit juice fermentation broth with the functions of beautifying and removing freckles is prepared by fermenting 20 parts by mass of mulberry and 4 parts by mass of hawthorn through mixed lactic acid bacteria, wherein the mass of the added mixed lactic acid bacteria is 0.1% of the total mass of the mulberry and the hawthorn, and the mixed lactic acid bacteria comprise lactobacillus plantarum and lactobacillus fermentum in a mass ratio of 1:1.
The prepared juice fermentation liquor with the functions of beautifying and removing freckles has 15g/L of titrating acid and 500U/g of content of superoxide dismutase.
A fruit juice fermented beverage with functions of beautifying and removing freckles comprises a fruit juice fermentation liquid and auxiliary materials, wherein the components in parts by weight are as follows:
the preparation method of the fruit juice fermented beverage comprises the following steps:
1) cleaning the mulberries and the hawthorns, centrifuging to remove water, and pulping in a pulping machine to obtain mixed pulp;
2) conveying the mixed serous fluid obtained in the step 1) into a fermentation tank through an aseptic pipeline, inoculating a mixed lactic acid bacteria strain, wherein the mixed lactic acid bacteria strain comprises lactobacillus plantarum and lactobacillus fermentum, the mass ratio of the lactobacillus plantarum to the lactobacillus fermentum is 1:1.2, the total mass of the mixed bacteria strain is 0.1% of the total mass of the mulberries and the hawthorns, and the concentrations of the lactobacillus plantarum and the lactobacillus fermentum are 1.2 multiplied by 1011cfu/mL, stirring uniformly, and fermenting for 8 weeks to obtain juice fermentation liquor; wherein the conditions of the fermentation process are controlled as follows: setting the temperature to be 31 ℃ within 1 week after the mixed lactic acid bacteria are inoculated; starting at 2 weeks after inoculation of the mixed lactic acid bacteria strain, the temperature was set at 28 ℃.
3) Sequentially adding collagen peptide, polydextrose, xylitol, calcium lactate, nicotinic acid and vitamin B6 into the juice fermentation broth obtained in the step 2), fully mixing, subpackaging into 30ml vials, and sterilizing at 121 ℃ for 20min to obtain the juice fermented beverage.
Example 3
The fruit juice fermentation broth with the functions of beautifying and removing freckles is prepared by fermenting 13 parts by mass of mulberry and 3 parts by mass of hawthorn through mixed lactic acid bacteria, wherein the mass of the added mixed lactic acid bacteria is 0.01 percent of the total mass of the mulberry and the hawthorn, and the mixed lactic acid bacteria comprise lactobacillus plantarum and lactobacillus fermentum with the active mass ratio of 1: 1.2.
The prepared juice fermentation liquor with the functions of beautifying and removing freckles has the titrating acid of 19g/L and the content of superoxide dismutase of 700U/g.
A fruit juice fermented beverage with functions of beautifying and removing freckles comprises a fruit juice fermentation liquid and auxiliary materials, wherein the components in parts by weight are as follows:
the preparation method of the fruit juice fermented beverage comprises the following steps:
1) cleaning the mulberries and the hawthorns, centrifuging to remove water, and pulping in a pulping machine to obtain mixed pulp;
2) conveying the mixed serous fluid obtained in the step 1) into a fermentation tank through an aseptic pipeline, inoculating mixed lactic acid bacteria, wherein the mixed lactic acid bacteria comprise lactobacillus plantarum and lactobacillus fermentum, the mass ratio of the lactobacillus plantarum to the lactobacillus fermentum is 1:1.2, the total mass of the mixed bacteria is 0.01% of the total mass of the mulberries and the hawthorns, and the concentration of the lactobacillus plantarum and the lactobacillus fermentum is 1.5 multiplied by 1011cfu/mL, stirring uniformly, and fermenting for 8 weeks to obtain juice fermentation liquor; wherein the conditions of the fermentation process are controlled as follows: setting the temperature to be 32 ℃ within 1 week after the mixed lactic acid bacteria are inoculated; starting at 2 weeks after inoculation of the mixed lactic acid bacteria strain, the temperature was set at 30 ℃.
3) Sequentially adding collagen peptide, polydextrose, xylitol, calcium lactate, nicotinic acid and vitamin B6 into the juice fermentation broth obtained in the step 2), fully mixing, subpackaging into 30ml vials, and sterilizing at 121 ℃ for 20min to obtain the juice fermented beverage.
Example 4
The fruit juice fermentation broth with the functions of beautifying and removing freckles is prepared by fermenting 17 parts by mass of mulberry and 4 parts by mass of hawthorn through mixed lactic acid bacteria, wherein the mass of the added mixed lactic acid bacteria is 0.05% of the total mass of the mulberry and the hawthorn, and the mixed lactic acid bacteria comprise lactobacillus plantarum and lactobacillus fermentum in a mass ratio of 1:1.
The prepared juice fermentation liquor with the functions of beautifying and removing freckles has the titrating acid of 20g/L and the content of superoxide dismutase of 950U/g.
A fruit juice fermented beverage with functions of beautifying and removing freckles comprises a fruit juice fermentation liquid and auxiliary materials, wherein the components in parts by weight are as follows:
the preparation method of the fruit juice fermented beverage comprises the following steps:
1) cleaning the mulberries and the hawthorns, centrifuging to remove water, and pulping in a pulping machine to obtain mixed pulp;
2) conveying the mixed serous fluid obtained in the step 1) into a fermentation tank through an aseptic pipeline, inoculating a mixed lactic acid bacteria strain, wherein the mixed lactic acid bacteria strain comprises lactobacillus plantarum and lactobacillus fermentum, the mass ratio of the lactobacillus plantarum to the lactobacillus fermentum is 1:1, the total mass of the mixed bacteria strain is 0.05 percent of the total mass of the mulberries and the hawthorns, and the concentrations of the lactobacillus plantarum and the lactobacillus fermentum are 1.3 multiplied by 1011cfu/mL, stirring uniformly, and fermenting for 8 weeks to obtain juice fermentation liquor; wherein the conditions of the fermentation process are controlled as follows: setting the temperature to be 31 ℃ within 1 week after the mixed lactic acid bacteria are inoculated; starting at 2 weeks after inoculation of the mixed lactic acid bacteria strain, the temperature was set at 27 ℃.
3) Sequentially adding collagen peptide, polydextrose, xylitol, calcium lactate, nicotinic acid and vitamin B6 into the juice fermentation broth obtained in the step 2), fully mixing, subpackaging into 30ml vials, and sterilizing at 121 ℃ for 20min to obtain the juice fermented beverage.
Example 5
The fruit juice fermentation broth with the functions of beautifying and removing freckles is prepared by fermenting 15 parts by mass of mulberry and 3.5 parts by mass of hawthorn through mixed lactic acid bacteria, wherein the mass of the added mixed lactic acid bacteria is 0.01 percent of the total mass of the mulberry and the hawthorn, and the mixed lactic acid bacteria comprise lactobacillus plantarum and lactobacillus fermentum in a mass ratio of 1: 1.5.
The prepared juice fermentation liquor with the functions of beautifying and removing freckles has the titrating acid of 20g/L and the content of superoxide dismutase of 1000U/g.
A fruit juice fermented beverage with functions of beautifying and removing freckles comprises a fruit juice fermentation liquid and auxiliary materials, wherein the components in parts by weight are as follows:
the preparation method of the fruit juice fermented beverage comprises the following steps:
1) cleaning the mulberries and the hawthorns, centrifuging to remove water, and pulping in a pulping machine to obtain mixed pulp;
2) conveying the mixed serous fluid obtained in the step 1) into a fermentation tank through an aseptic pipeline, inoculating a mixed lactic acid bacteria strain, wherein the mixed lactic acid bacteria strain comprises lactobacillus plantarum and lactobacillus fermentum, the mass ratio of the lactobacillus plantarum to the lactobacillus fermentum is 1:1.5, the total mass of the mixed bacteria strain is 0.01% of the total mass of the mulberries and the hawthorns, and the concentration of the lactobacillus plantarum and the lactobacillus fermentum is 1.1 x 1011cfu/mL, stirring uniformly, and fermenting for 8 weeks to obtain juice fermentation liquor; wherein the conditions of the fermentation process are controlled as follows: setting the temperature to be 30 ℃ within 1 week after the mixed lactic acid bacteria are inoculated; starting at 2 weeks after inoculation of the mixed lactic acid bacteria strain, the temperature was set at 28 ℃.
3) Sequentially adding collagen peptide, polydextrose, xylitol, calcium lactate, nicotinic acid and vitamin B6 into the juice fermentation broth obtained in the step 2), fully mixing, subpackaging into 30ml vials, and sterilizing at 121 ℃ for 20min to obtain the juice fermented beverage.
Example 6
This example is an acute toxicity test of a juice broth
Because the main raw materials of the mulberry and the hawthorn are fermented, certain uncertain factors exist. For safety, according to the toxicology evaluation program of health food inspection and evaluation technical specifications (2003 edition), the first acute toxicity test was performed on the "juice fermentation broth" prepared by the present invention in comparison with the four stages and contents of the toxicology evaluation test for health food safety, and the LD50 was 13000 mg/kg. The juice fermentation broth is classified according to the dose of acute toxicity (LD50) and is of an actual non-toxic grade (rat orally takes LD50, mg/kg, 5001-15000, which is equivalent to the lethal dose of 250-500 g/kg).
Example 7
Human body experiments are carried out according to technical specifications for health food inspection and evaluation (2003 edition) in an inspection method for assisting in beautifying and freckle removing functions.
1. Subject inclusion criteria
Volunteers who were subjected to physical examination to the following conditions:
(1) the face is light brown to dark brown, and the clear spot is generally distributed symmetrically and has no inflammatory expression and scales;
(2) no obvious subjective symptoms;
(3) it occurs mainly after puberty, and women frequently;
(4) the disease condition is seasonal, and the disease is severe in summer and mild in winter;
(5) has no obvious endocrine diseases, and eliminates pigmentation caused by other diseases.
2. Subject exclusion criteria.
(1) Age below eighteen years and above 65 years, gestation and lactation women, allergic constitution;
(2) patients with serious diseases of cardiovascular, cerebrovascular, liver, kidney and hemopoietic system, endocrine diseases, and psychosis;
(3) alcoholics or smokers;
(4) taking articles related to the tested functions in a short time affects the judgment of the result.
(5) If the test sample is not taken as prescribed, the efficacy or data are not completely judged to affect the efficacy or safety judgment.
3. Design of experiments and grouping requirements
Two control designs, self and group, were used. The test group and the control group are randomly divided according to the chloasma color of the subject and the area condition, and the main factors influencing the result, such as outdoor activity condition, gender, age and the like, are considered as much as possible to carry out balance test so as to ensure comparability among the groups.
The test substance is a drink prepared according to the formula and the process in the embodiment 1 of the invention. 120 female subjects who meet the above conditions were selected on a voluntary basis. The experimental group was given the test substance and the control group was given the same property without placebo (out of 3 cases). The fermented fruit juice beverage is taken 2 times a day in 1 bottle each time, the dosage is 20 ml/day, and the test subject stops using the spot removing product, medicine and health food with the effects of caring skin and removing speckle for 30 consecutive days.
4. And (5) observing the efficacy.
The integral values were counted before and after the trial according to the severity of the symptoms (severe 3 points, moderate 2 points, mild 1 point), and the improvement rates were calculated for the improvement of the main symptoms (2 points for improvement and 1 point for improvement, respectively).
4.1 detection of chloasma on the head
4.1.1 area size changes
Measuring the major diameter and the width diameter of the same chloasma before and after the test by using a ruler, and calculating the area (cm)2)。
4.1.2 color shade change
According to the judgment standard of the depth of the chloasma color according to a brown (Y + M + Bk, namely the stack color of yellow + fuchsin + black) color card in a practical standard color card (first edition): i degree (15, 20, 5), II degree (30, 40, 10), III degree (40, 60, 15).
5. Determination of freckle-removing efficacy
The effect is shown: the chloasma color is reduced by II degree, or the area is reduced by more than or equal to 30 percent, and no new yellow brown spot is generated.
The method has the following advantages: the chloasma color is reduced by I degree, or the area is reduced by less than 30 percent, and no new chloasma is generated by more than 10 percent.
And (4) invalidation: the area of chloasma is reduced by less than 10 percent, and the color is not obviously changed.
The change in the shade of chloasma is shown in Table 1.
TABLE 1 change of chloasma in the test and control groups
| Group of | Number of examples | Before tasting | After eating trial | Difference value |
| Test food group | 60 | 2.36±0.44 | 2.06±0.30**## | -0.25±0.39** |
| Control group | 57 | 2.30±0.45 | 2.29±0.56 | -0.02±0.20 |
The change in the size of the chloasma area is shown in table 2.
TABLE 2 change of chloasma area in the test and control groups
| Group of | Number of examples | Before tasting (mm)2) | After tasting (mm)2) | Difference (mm)2) |
| Test food group | 60 | 6121±2373 | 4963±1680**## | 1158±873** |
| Control group | 57 | 6230±1968 | 6049±2091 | 88±365 |
Note: internal comparison p <0.01, # # external comparison p <0.01
The results of efficacy evaluation before and after the test (examples,%) are shown in table 3.
TABLE 3 Pre-and post-test efficacy determination results for the test group and the control group
| Group of | Number of examples | Is effective | Invalidation | High efficiency |
| Test food group | 60 | 43 | 17 | 71.67％ |
| Control group | 57 | 0 | 57 | 0 |
Note: comparison within group p <0.01
6. Conclusion
60 chloasma subjects take the fruit juice fermented beverage prepared in example 1 according to requirements for 30 days, the average chloasma area is reduced by 1158 +/-873 mm2(P <0.01), the color is lightened, the average color card is reduced by 0.23 +/-0.37 degrees (P <0.01), the effective case is 43, the total efficiency is 71.67%, and the fruit juice fermented beverage has the effect of removing chloasma.
Claims (8)
1. The fruit juice fermentation liquor with the functions of beautifying and removing freckles is characterized by being prepared by fermenting mulberries and hawthorn fruits through mixed lactic acid bacteria, wherein the mulberries and the hawthorn fruits are prepared from the following raw materials in parts by weight: 10-20 parts of mulberry and 2-4 parts of hawthorn; the added mixed lactobacillus accounts for 0.01-0.1% of the total mass of the mulberries and the hawthorns;
the mixed lactobacillus is lactobacillus plantarum and lactobacillus fermentum with a mass ratio of 1:0.8-1.5, and the concentrations of lactobacillus plantarum and lactobacillus fermentum are 1.0 × 1011-1.5×1011cfu/g；
The titrating acid of the juice fermentation liquor is 15-20g/L, and the content of superoxide dismutase is 500-1000U/g.
2. The fruit juice fermented beverage with the functions of beautifying and removing freckles is characterized by consisting of the fruit juice fermented liquid of claim 1 and auxiliary materials, wherein the components in parts by weight are as follows:
3. the juice fermented drink according to claim 2, wherein the water-soluble dietary fiber is polydextrose.
4. The method for preparing the fruit juice fermented drink according to claim 2 or 3, comprising the steps of:
1) cleaning the mulberries and the hawthorns, centrifuging to remove water, and pulping in a pulping machine to obtain mixed pulp;
2) conveying the mixed slurry obtained in the step 1) into a fermentation tank, inoculating a mixed lactic acid bacterium, uniformly stirring, and fermenting for 6-8 weeks to obtain a juice fermentation broth;
3) sequentially adding collagen peptide, water-soluble dietary fiber, xylitol, calcium lactate, nicotinic acid and vitamin B6 into the juice fermentation broth obtained in the step 2), mixing, subpackaging into small bottles, and sterilizing at 121 ℃ for 20min to obtain the juice fermented beverage.
5. The method for preparing the fruit juice fermented beverage according to claim 4, wherein the mixed lactic acid bacteria inoculated in the step 2) is 0.01 to 0.1% by mass of the total mass of the mulberries and the hawthorns.
6. The method for preparing the fruit juice fermented drink according to claim 4, wherein the mixed lactic acid bacteria are Lactobacillus plantarum and Lactobacillus fermentum in a mass ratio of 1:0.8-1.5, and the concentrations of the Lactobacillus plantarum and the Lactobacillus fermentum are both 1.0 x 1011-1.5×1011cfu/g。
7. The method for preparing the fruit juice fermented drink according to claim 4, wherein the fermentation conditions in the step 2) are controlled as follows: setting the temperature to be 30-32 ℃ within 1 week after the mixed lactic acid bacteria are inoculated; starting at 2 weeks after inoculation of the mixed lactic acid bacteria strain, the temperature was set at 26-30 ℃.
8. The application of the fruit juice fermentation liquid in the health-care food for assisting in beautifying and removing freckles, which is disclosed by claim 1, is characterized in that the fruit juice fermentation liquid is added into the health-care food for assisting in beautifying and removing freckles as an active ingredient.
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| CN109170416A (en) * | 2018-07-23 | 2019-01-11 | 北京万莱康营养与健康食品科学技术研究院有限公司 | A kind of composite probiotics ferment fruit juice composition and preparation method thereof adjusting intestinal microecology |
| CN112493486A (en) * | 2020-11-27 | 2021-03-16 | 湖南洋利农林科技有限责任公司 | Oral liquid with honeysuckle flower, cape jasmine fruit and honeysuckle flower for beautifying face and preparation method thereof |
| CN112608858A (en) * | 2020-12-17 | 2021-04-06 | 上海交大昂立股份有限公司 | Probiotic composition with freckle removing effect and application thereof |
| CN115399413A (en) * | 2022-08-23 | 2022-11-29 | 中科爱伽(天津)医用食品有限公司 | Whitening and anti-aging composition, preparation process and application thereof |
| CN115581299A (en) * | 2022-08-30 | 2023-01-10 | 西华大学 | Anti-oxidation fermented wolfberry and mulberry oral liquid and preparation method thereof |
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Denomination of invention: Fruit juice fermented beverage with beauty and freckle removal function and its preparation method Granted publication date: 20210119 Pledgee: Jiangmen Rural Commercial Bank Co.,Ltd. Muzhou Branch Pledgor: JIANGMEN SANGKESHI BIOTECHNOLOGY CO.,LTD. Registration number: Y2024980012947 |