CN106942561A - A kind of beverage composition for treating dental erosion and preparation method and application - Google Patents
A kind of beverage composition for treating dental erosion and preparation method and application Download PDFInfo
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- CN106942561A CN106942561A CN201710302406.9A CN201710302406A CN106942561A CN 106942561 A CN106942561 A CN 106942561A CN 201710302406 A CN201710302406 A CN 201710302406A CN 106942561 A CN106942561 A CN 106942561A
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- 238000003379 elimination reaction Methods 0.000 description 1
- 208000030172 endocrine system disease Diseases 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 230000029142 excretion Effects 0.000 description 1
- 208000010706 fatty liver disease Diseases 0.000 description 1
- 210000003608 fece Anatomy 0.000 description 1
- 229930003944 flavone Natural products 0.000 description 1
- 150000002212 flavone derivatives Chemical class 0.000 description 1
- 235000011949 flavones Nutrition 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 230000007760 free radical scavenging Effects 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 210000004051 gastric juice Anatomy 0.000 description 1
- 230000007661 gastrointestinal function Effects 0.000 description 1
- 230000007674 genetic toxicity Effects 0.000 description 1
- 231100000025 genetic toxicology Toxicity 0.000 description 1
- 210000004195 gingiva Anatomy 0.000 description 1
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- 239000008103 glucose Substances 0.000 description 1
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- 239000000745 gonadal hormone Substances 0.000 description 1
- 229940087559 grape seed Drugs 0.000 description 1
- 229940094952 green tea extract Drugs 0.000 description 1
- 235000020688 green tea extract Nutrition 0.000 description 1
- 230000012010 growth Effects 0.000 description 1
- 230000002650 habitual effect Effects 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 208000019622 heart disease Diseases 0.000 description 1
- 210000005003 heart tissue Anatomy 0.000 description 1
- 229960001340 histamine Drugs 0.000 description 1
- 235000012171 hot beverage Nutrition 0.000 description 1
- 230000004727 humoral immunity Effects 0.000 description 1
- 206010020718 hyperplasia Diseases 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
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- 229940116108 lactase Drugs 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 239000010985 leather Substances 0.000 description 1
- 210000000265 leukocyte Anatomy 0.000 description 1
- 150000002617 leukotrienes Chemical class 0.000 description 1
- 235000019421 lipase Nutrition 0.000 description 1
- 208000014018 liver neoplasm Diseases 0.000 description 1
- 210000004698 lymphocyte Anatomy 0.000 description 1
- 210000002540 macrophage Anatomy 0.000 description 1
- MDZKJHQSJHYOHJ-LLICELPBSA-N maslinic acid Chemical compound C1[C@@H](O)[C@H](O)C(C)(C)[C@@H]2CC[C@@]3(C)[C@]4(C)CC[C@@]5(C(O)=O)CCC(C)(C)C[C@H]5C4=CC[C@@H]3[C@]21C MDZKJHQSJHYOHJ-LLICELPBSA-N 0.000 description 1
- 231100000682 maximum tolerated dose Toxicity 0.000 description 1
- 230000009245 menopause Effects 0.000 description 1
- 230000003923 mental ability Effects 0.000 description 1
- 230000004089 microcirculation Effects 0.000 description 1
- 210000003632 microfilament Anatomy 0.000 description 1
- 230000003020 moisturizing effect Effects 0.000 description 1
- 238000010172 mouse model Methods 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 230000002107 myocardial effect Effects 0.000 description 1
- 210000004165 myocardium Anatomy 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 235000008935 nutritious Nutrition 0.000 description 1
- 238000003305 oral gavage Methods 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 229910052763 palladium Inorganic materials 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 210000003899 penis Anatomy 0.000 description 1
- 230000036513 peripheral conductance Effects 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 230000036581 peripheral resistance Effects 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 229920002414 procyanidin Polymers 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 239000001397 quillaja saponaria molina bark Substances 0.000 description 1
- 230000002285 radioactive effect Effects 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
- 230000002040 relaxant effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000033764 rhythmic process Effects 0.000 description 1
- IKGXIBQEEMLURG-NVPNHPEKSA-N rutin Chemical compound O[C@@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@H]1OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H](OC=2C(C3=C(O)C=C(O)C=C3OC=2C=2C=C(O)C(O)=CC=2)=O)O1 IKGXIBQEEMLURG-NVPNHPEKSA-N 0.000 description 1
- 229930182490 saponin Natural products 0.000 description 1
- 150000007949 saponins Chemical class 0.000 description 1
- 208000005687 scabies Diseases 0.000 description 1
- 231100000241 scar Toxicity 0.000 description 1
- 230000036280 sedation Effects 0.000 description 1
- 230000008313 sensitization Effects 0.000 description 1
- 230000001235 sensitizing effect Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 230000001568 sexual effect Effects 0.000 description 1
- 201000005113 shigellosis Diseases 0.000 description 1
- 238000004904 shortening Methods 0.000 description 1
- 230000037394 skin elasticity Effects 0.000 description 1
- 230000003860 sleep quality Effects 0.000 description 1
- 230000019100 sperm motility Effects 0.000 description 1
- 210000000130 stem cell Anatomy 0.000 description 1
- 229910052712 strontium Inorganic materials 0.000 description 1
- CIOAGBVUUVVLOB-UHFFFAOYSA-N strontium atom Chemical compound [Sr] CIOAGBVUUVVLOB-UHFFFAOYSA-N 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 235000013616 tea Nutrition 0.000 description 1
- 210000001550 testis Anatomy 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 235000015961 tonic Nutrition 0.000 description 1
- 230000001256 tonic effect Effects 0.000 description 1
- 229960000716 tonics Drugs 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 229940126680 traditional chinese medicines Drugs 0.000 description 1
- 150000003626 triacylglycerols Chemical class 0.000 description 1
- 201000009160 urethral calculus Diseases 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
- VHBFFQKBGNRLFZ-UHFFFAOYSA-N vitamin p Natural products O1C2=CC=CC=C2C(=O)C=C1C1=CC=CC=C1 VHBFFQKBGNRLFZ-UHFFFAOYSA-N 0.000 description 1
- 230000002747 voluntary effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/385—Concentrates of non-alcoholic beverages
- A23L2/39—Dry compositions
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to a kind of beverage composition for treating dental erosion and preparation method and application, the present invention is used as active component using medicine-food two-purpose composition, each composition is shown in that mutual compatibility is coordinated, respectively take the chief, safely and effectively, the good taste and security of product are ensure that, active component purposes is have also been enlarged, it is to avoid the pained smell of medicine, while said composition liver-kidney tonifying, enriching yin improving eyesight, blood fat-reducing blood pressure-decreasing, flat liver improving eyesight, cool blood can prevent and treat hypertension, high fat of blood, sleep can also be improved, regulation metabolism and physiological function, anti-aging strengthen immunity of organisms.In addition, sanchi flower bitter, hawthorn is sour, steviol glycoside is micro- sweet, and black fruit fructus lycii fruit is fresh strong, and grape pip is sweet, comprehensive taste good.
Description
Technical field
The present invention relates to field of food, more particularly to a kind of beverage composition for treating dental erosion.
Background technology
On the origin of drug discovery and food, the allusion for being especially reflected in " shennong went into the mountains collecting, tasting and testing different kinds of herbs to be used as medicine ".Chinese nation's Farming Culture
With a long history, legendary god of farming Xuan Yuanshi is the first ancestor of Chinese nation's Farming Culture according to legend.A variety of, land merchant is recorded to it《Newspeak
Road base first》Description:" people drink bloodstained garment fur to eat meat.As for the legendary god of farming, think row worm beast, it is difficult to support the people, be ask it is edible it
Thing, tastes the reality of hundred grass, examines bitter taste, believer food five cereals." the visible legendary god of farming makes Chinese nation in period in time immemorial by eating birds and animals raw
The hunting epoch enter the agriculture time based on food grass.Current anthropologist is by studying the tooth knots of the mankind's different periods of history
Structure, it is carnivorous at first that can prove the mankind, is then turned to omnivorous.《Cure Left》Cloud:The legendary god of farming " taste the flavour of hundred grass, the sweetness and bitterness of fountain,
Make the people know to keep away just, at the moment, one day and meet 70 poison.This its taste hundred grass for the other people can trencherman, rather than fixed medicine.”
The allusion of this section " shennong went into the mountains collecting, tasting and testing different kinds of herbs to be used as medicine, one day and meet 70 poison " is also that many honor legendary gods of farming of current descendant are herbal (medicine) finders
Foundation.From the point of view of ancient book record, poison and medicine are not distinguished strictly earliest.《All gift heavenly officials》Carry:" doctor slaps the government decree of doctor,
Poly- poison is for doctor's thing ".Poison is with can be used for medical treatment medicine.This section of words author specially illustrates the purpose that shennong went into the mountains collecting, tasting and testing different kinds of herbs to be used as medicine again
It is search of food and non-drug, is also just illustrating the discovery of medicine and the association of food.Tao Hongjing exists《Bencao jizhu》Sequence is recorded
In mention that " lotus root skin dissipates blood, rises from cook;Lead a cow and relieve oedema or abdominal distension through diuresis or purgation, closely go out wild old ", the discovery that also reflects medicine is come from people's lives
Practice, especially diet activity(It is unimodal, Huang Luqi, Guo Juan etc., history and general situation of development [J] the life section of integration of drinking and medicinal herbs
Learn, 2015,27(8):1061-1069).
The medicine-food two-purpose beverage plant resource of China is enriched very much, and considerable part also locates dry wild state, is opened to sustainable
Hair provides substantial amounts of germ plasm resource.And some medicine-food two-purpose beverage plant resources have been carried out scale cultivation, such as strand
Indigo plant, mulberry, Ilex Latifolia Thunb, ginkgo etc., are the raw material basis that abundance has been established in industrialization development.As scientific and technological level is improved constantly, people
The active ingredient of such plant and pharmacological action are able to deeper into comprehensive understanding so that development and application work, which has, more may be used
The theoretical foundation leaned on.And with the continuous lifting of foods processing technique and equipment level, production active constituent content is high, quality better
Herbal beverage become a reality.
Sanchi flower taste is cool in nature, there is cool blood, can neutralize internal hot gas, while can also recuperating qi-blood operation, promoting blood circulation
Promote blood circulation, dredging the channel, promote heat toxin to excrete, extract can adjust central nervous system, improve the excitement of brain with suppressing
Process, is allowed to tend to balance;The mental ability with manual labor can be improved, operating efficiency is improved, and play the role of antifatigue;Heat
Preserved material, water decoction and decocting alcohol extract have obvious dilating effect to isolated rabbit ear blood vessel;Total saponin in sanchi flower, in zoopery
In play the role of of short duration reduction dog arterial pulse blood pressure and peripheral resistance.Notoginseng polysaccharide is to promote immune active ingredient, pseudo-ginseng
Two kinds of colored polysaccharide can promote the function through macrophage.Notoginseng triterpenes can also improve blood middle leukocytes sum and lymphocyte
Percentage, promotes the hyperplasia of candidate stem cell, moreover it is possible to improve the generation of humoral immunity antibody to a certain extent.Body inner lipid
Peroxide(Lipid peroxide, LPO)Abnormal accumulation disrupting biofilm normal function, promote aging and artery congee
The various diseases such as sample hardening occur.It is demonstrated experimentally that Radix Notoginseng powder is tuned into paste with distilled water, the content of LPO in rat blood can be made
Significantly reduce, the LOP in brain tissue is reduced significantly, with anti-aging effects.
Black fruit fructus lycii is the fruit of Solanaceae Lycium black fruit fructus lycii, Tibetan medicine name " other agate ".《Uygur medicine will》Record,
Uygur doctor is among the people to be used as nourishing by force often with lycium ruthenicum fruit and root skin treatment urethral calculus, tinea scabies, gingiva bleeding gingival hemorrhage etc.
Strong, improving eyesight and depressor.《Four doctor's allusion quotations》、《Jingzhubencao》Deng Tibetan medicine classical works record lycium ruthenicum be used for treat cardiopyretic disease,
Heart disease, irregular menstruation, menopause etc., and drug effect is notable.It is among the people to make strengthening by means of tonics, it is depressured medication.Black fruit fructus lycii is sweet, mild-natured,
Rich in protein, fat, carbohydrate, free amino acid, organic acid, mineral matter, trace element, alkaloid, vitamin C, B1, B2 etc.
Various nutritional ingredients.And contain abundant black fruit pigment-natural procyanidins, its OPC(Common OPC)Content exceedes
Blueberry.Anti-aging is one of topmost effect of lycium ruthenicum, and substantial amounts of anthocyanidin can be good at anti-oxidant, elimination human body freedom
Base, the effect with significant anti-aging.Anthocyanidin can pass through blood-brain barrier, and cranial nerve can be protected not oxidized, can stable brain
Function of organization, protects brain not injured by harmful chemical and toxin.After anthocyanidin in edible lycium ruthenicum, sleep quality
It can be significantly improved.Lycium ruthenicum is the same with red matrimony vine being capable of tonifying kidney and benefiting sperm, the anthocyanidin in lycium ruthenicum
(Anthocyanosides)Have functions that to remove free radical, can also allow cancer cell not spread smoothly, more health are protected whereby
Cell from being corroded by cancer cell.Black fruit fructus lycii can also prevent and treat diabetes, and with obvious antifatigue, liver protection, moreover it is possible to it is anti-
Cardiovascular System is protected in tumour, dredging vascellum, step-down.
The Tang Dynasty《Bencao Shiyi》In once recorded:" money of saline cistanche three, three decoct a system, and hot drink takes it, and penis does not wane all the life ".Meat
Contain a large amount of amino acid, cystine, vitamin and the rare nutritious tonifying composition of mineral matter in desert cistanche, to male's kidney, testis, the moon
The sexual organs such as stem, cavernous body have great help effect, can also effectively improve sperm motility and quality.Kidney storing essence, main bone life
Marrow, is the congenital foundation, is motive power and source that muscle power is produced.Prolonged exercise, when many degree fatigues can cause the testosterone to decline
The principal element that body movement ability declines and recovery process extends.Saline cistanche can prevent and treat testosterone reduction caused by motion, promote
Enter the secretion of hypophysis gonadal hormone, accelerate fatigue recovery, improve locomitivity.It can also make after fixed quantitative load motion, blood lactase acid heap
Product is reduced, and is removed and is accelerated, and body acid-fast ability is improved.Saline cistanche has protection ischemic myocardium, reducing blood lipid, antiatherosclerosis
With antithrombus formation, reduction peripheral vascular resistance, step-down, anti-fatty liver and a variety of pharmacological activity such as antitumor.Have in saline cistanche
Effect composition phenylethanoid glycosides have improvement microcirculation, and softening blood vessel, the increase heart, brain and the circulation of outer four limbs peripheral vessel reach protection
The effect of the blood cerebrovascular and nervous system.The traditional Chinese medical science thinks that saline cistanche enters kidney and large intestine channel, tonifies the kidney and support yang with moistening dryness for relaxing bowels.Saline cistanche
The water decoction of class medicine has obvious defecating feces excretion, can improve enterocinesia, suppresses the moisture absorption of large intestine, when shortening defecation
Between.To the elderly habitual constipation, physically weak constipation and puerpera's puerperal constipation are evident in efficacy.
Grape pip is that products therefrom after Grape Skin, grape pedicel is separated after drying, with energy is high, price is low, nontoxic pair
Effect etc..Grape pip energy is anti-oxidant, desalinates color spot, adjust dry skin caused by endocrinopathy, reduces melanin, whitening flesh
Skin, functions of removing chloasma;Cell division and regeneration can be stimulated, cells of superficial layer is activated, wrinkle, anti-aging is reduced;Before anti-
The effect of row gland cancer, anti-liver neoplasm, can also resist the damage of nervous system;Grape-kernel oil is made up of grape seed cold pressing,
Due to the vegetalitas Omega-3 that can not be voluntarily manufactured rich in human body(Leukotrienes)And unrighted acid, it is accordingly regarded as one kind
Edible health-care oil.Grape seed extract has the good reputation of " skin vitamin " and " oral cosmetic product ", can protect collagen, change
Kind skin elasticity and gloss, whitening, moisturizing, nti-freckle;Reduce wrinkle, keep the soft and moist smooth of skin;Remove acne, healing scar
Trace.Go deep into the release that cell fundamentally suppresses sensitizing factor " histamine ", improve tolerance of the cell to anaphylactogen;Remove sensitization
Free radical, anti-inflammatory, antiallergy;Stable skin heart tissue, alleviates the various allergy such as nettle rash, dry leather heat, allergic rhinitis
Shape;Effectively regulation immunity of organisms, thoroughly improves allergic constitution.Grape seed extract is the highest of the plant origin found so far
One of antioxidant of effect, in vivo and in vitro experiment shows that the antioxidant effect of grape seed extract is vitamin C and Wei Sheng
30-50 times of plain E.Superpower anti-oxidant efficiency has the strength effect removed free radical, improve body immunity.Grape pip essence
China containing abundant bioflavonoid, be strength elite molecule, for Green Tea Extract (free radical) with safeguarding that microfilament blood vessel is good for
Health.
The traditional Chinese medical science thinks that hawthorn enters spleen, the warp of stomach two, can treat a variety of the spleen and stomach illnesses.In addition to anorexia, eating accumulation,
Fine antidiarrheal dysentery.Hawthorn energy prevention and cure of cardiovascular disease, with expansion of blood vessels, increase coronary blood flow, improves heart vigor, excitement
Central nervous system, reduce blood pressure and cholesterol, softening blood vessel and diuresis and sedation.Hawthorn can reduce serum cholesterol and
Triglycerides, effectively prevents and treats atherosclerosis;Hawthorn can also play cardiac stimulant and pre- angina pectoris by strengthening myocardial contractive power
Effect.General flavone in hawthorn plays the role of expansion of blood vessels and lasting buck.According to pharmacological testing, charred FRUCTUS CRATAEGI decoction in vitro test
There is obvious inhibitory action to various shigella dysenteriaes and Pseudomonas aeruginosa, Escherichia coli, golden yellow coccus, bacillus anthracis etc., therefore
Treatment available for bacillary dysentery.Hawthorn contains lipase, can promote fat digestion, and can increase the secretion of gastric juice, promotes to disappear
Change.There is certain adjustment effect to gastrointestinal function, to hyperactive duodenum smooth muscle of exempting from inhibitory action, in face of relaxation
Rat pipe smooth muscle have slight enhancing contraction.Crataegolic acid extract solution and the aqueous solution to acetylcholine and Ba 2 cause
Exempt from, the in vitro gastrointestinal smooth muscle of mouse is shunk with obvious inhibiting effect, and have to the pipe smooth muscle under rat tension and relaxation state and promote to receive
Contracting is acted on.There is first of fruit pectin content shelter, in hawthorn up to 6.4%, and pectin, and according to current research, it has radio-opaque substance
Effect, the radioactive element walked half from internal band(Strontium, cobalt, palladium etc.).Pectin also has absorption and antibacterial properties, can be from intestines
Remove bacterium, toxin and hold onto moisture.
Decoction is always that tcm clinical practice uses topmost formulation from ancient times to the present, and with easy absorption, work rapid, curative effect
Certainly the characteristics of.The traditional Chinese medical science is particular about diagnosis and treatment, and only decoction can be competent at card plus-minus, flexibility sanction.However, there is mouth in decoction
Sense is very poor, and the shortcomings of pained hardly possible is swallowed, the rhythm of life of modern people is accelerated, and when facing oral medicine selection, is more likely to naturally
Selection takes more convenient, the acceptable medicine of mouthfeel and formulation;In product processing, the protection to oxidizable composition is also
At present in the product process such as production food, health products the problem of most attention, how on the basis of manufacture qualified products, effectively
Protect ingredient also this area important topic;In addition, how to expand existing medical and edible dual purpose plant purposes, exploitation new product is also
At present under big health idea the problem of urgent need to resolve.
The content of the invention
In order to solve the above technical problems, to provide a kind of beverage composition for treating dental erosion, it is characterised in that it is by following raw material
Composition:10-50 parts of black fruit fructus lycii, 30-80 parts of sanchi flower, 10-50 parts of grape pip, 50-100 parts of saline cistanche, 10-20 parts of hawthorn,
0.1-0.5 parts of steviol glycoside, acceptable auxiliary material on food.
According to a kind of above-mentioned beverage composition for treating dental erosion, it is characterised in that it is composed of the following raw materials by weight:Black fruit fructus lycii 45
Part, 70 parts of sanchi flower, 45 parts of grape pip, 60 parts of saline cistanche, 15 parts of hawthorn, 0.2 portion of steviol glycoside is acceptable auxiliary on food
Material.
According to a kind of preparation method of above-mentioned beverage composition for treating dental erosion, it is characterised in that be prepared into the preparation method of beverage
It is as follows:
A. specified volume raw material is weighed, is cleaned, it is standby;
B. black fruit fructus lycii is taken, is put into disintegrating machine and crushes, broken product, which are put into drier, vacuumizes 5-10min, squeezes the juice, filtering,
Black fruit fructus lycii juice is obtained, 2-5 DEG C of sealing contains standby, gained black fruit fructus lycii slag is collected standby;
C. saline cistanche is taken, is placed in historrhexis's machine and crushes, obtain saline cistanche fragment;
D. grape pip is taken, is placed in pulverizer and crushes, obtain grape pip powder and mince;
E. take above-mentioned black fruit fructus lycii slag, saline cistanche fragment, grape pip powder to mince, sanchi flower, hawthorn plus the immersion of 30-50 DEG C of water
15-30min, 30-70% edible alcohol are Extraction solvent, liquid ratio 20-10:1, extraction time 60-120min, ultrasonic power 80-
200W, 30-50 DEG C of extraction temperature extracts 1-3 times, obtains extract solution;
F. gained black fruit fructus lycii juice in step b is mixed with extract solution obtained by step e, stands 16-24h, filtering takes supernatant,
Concentration, addition 10-20% percentage by weight beta-schardinger dextrins are allocated in concentrate, are mixed, are obtained mixed liquor;
G. mixed liquor is preheated, is spray-dried, 180~200 DEG C of hot blast temperature, 25~30m of hot air flow is adjusted3/ h, pan feeding
0.15~0.25L/h of flow.
According to a kind of above-mentioned preparation method of beverage composition for treating dental erosion, it is characterised in that:
(1)In step b, the pumpdown time is 7-8min, is squeezed the juice, and sealing contains temperature for 3-5 DEG C;
(2)In step e, plus 30-35 DEG C of water immersion 15-20min, 40-50% edible alcohols are Extraction solvent, liquid ratio 18-15:
1, extraction time 60-90min, ultrasonic power 100-150W, 35-45 DEG C of extraction temperature are extracted 1-2 times;
(3)In step f, time of repose is 18-20h, and beta-schardinger dextrin addition is 12-16% percentage by weights;
(4)In step g, preheating temperature is 60-80 DEG C, 185~195 DEG C of hot blast temperature, 26~28m of hot air flow3/ h, enters stream
0.18~0.22L/h is measured, get dry extract powder.
Application of the above-mentioned beverage composition for treating dental erosion in health products, food or specific use beverage is prepared.
The application of above-mentioned beverage composition for treating dental erosion, the purposes includes hypoglycemic, improvement sleep.
The application of the beverage composition for treating dental erosion, it is characterised in that the food or health products are granule, tablet, powder, mouth
Take liquor type.
The quality determining method of the beverage composition for treating dental erosion, it is characterised in that the preparation method system as described in claim 3 or 4
The product obtained, is not less than 5% with determined by ultraviolet spectrophotometry Determination of Polyphenols.
Sanchi flower in this beverage composition for treating dental erosion that the present invention is provided, cool in nature, Return liver kidney channel, The flat liver of heat-clearing, promoting blood circulation step-down;With
The mild-natured enter liver kidney of black fruit fructus lycii, kind nourishing liver and kidney, benefiting shrewd head, oxidation resistance is strong;Saline cistanche is nourishing liver and kidney, strong body,
Sleep can be improved;Hawthorn scattered stasis, promoting digestion and removing indigestion, hypotensive, reducing blood lipid;Grape pip dissipates stagnation resolvation knot, strengthen immunity, drop
Fat.The present invention is using medicine-food two-purpose composition as active component, and each composition is shown in that mutual compatibility is coordinated, and respectively takes the chief, safely and effectively,
The good taste and security of product are ensure that, active component purposes is have also been enlarged, it is to avoid the pained smell of medicine, simultaneously should
Composition liver-kidney tonifying, enriching yin improving eyesight, blood fat-reducing blood pressure-decreasing, flat liver improving eyesight, cool blood can prevent and treat hypertension, high fat of blood, also
Sleep, regulation metabolism and physiological function, anti-aging can be improved, strengthen immunity of organisms.In addition, sanchi flower bitter, hawthorn
Sour, steviol glycoside is micro- sweet, and black fruit fructus lycii fruit is fresh strong, and grape pip is sweet, comprehensive taste good.
Embodiment
Embodiment one
10 parts of black fruit fructus lycii, 30 parts of sanchi flower, 10 parts of grape pip, 50 parts of saline cistanche, 10 parts of hawthorn, 0.1 part of steviol glycoside, food
Upper acceptable auxiliary material.
Its preparation method is:
A. specified volume raw material is weighed, is cleaned, it is standby;
B. black fruit fructus lycii is taken, is put into disintegrating machine and crushes, broken product, which are put into drier, vacuumizes 5min, squeezes the juice, filtering is obtained
Black fruit fructus lycii juice, 2 DEG C of sealings contain standby, and gained black fruit fructus lycii slag is collected standby;
C. saline cistanche is taken, is placed in historrhexis's machine and crushes, obtain saline cistanche fragment;
D. grape pip is taken, is placed in pulverizer and crushes, obtain grape pip powder and mince;
E. take above-mentioned black fruit fructus lycii slag, saline cistanche fragment, grape pip powder to mince, sanchi flower, hawthorn plus the immersion of 30 DEG C of water
15min, 30% edible alcohol is Extraction solvent, liquid ratio 20:1, extraction time 60min, ultrasonic power 80W, extraction temperature 30
DEG C, extract 1 time, obtain extract solution;
F. gained black fruit fructus lycii juice in step b is mixed with extract solution obtained by step e, stands 16h, filtering takes supernatant, dense
Contracting, 10% percentage by weight beta-schardinger dextrin is added in concentrate and is allocated, and is mixed, is obtained mixed liquor;
G. mixed liquor is preheated, is spray-dried, 180 DEG C of hot blast temperature, hot air flow 25m is adjusted3/ h, pan feeding flow
0.15L/h, get dry extract powder, adds steviol glycoside, mixes, produces solid beverage.
Or appropriate 70% edible ethanol will be added in the mixture of above-mentioned addition steviol glycoside, by " that holds is agglomerating, pinches i.e.
Dissipate " principle prepare softwood, be prepared into granule according to conventional process for producing granula.
Or the mixture of above-mentioned addition steviol glycoside is made into adhesive with 70% edible ethanol, prepared using boiling granulating method
Into particle, compressing tablet, piece agent.
With polyphenol content in the above-mentioned solid beverage of determined by ultraviolet spectrophotometry, it is 5.1% to measure polyphenol content.
Embodiment two
50 parts of black fruit fructus lycii, 80 parts of sanchi flower, 50 parts of grape pip, 100 parts of saline cistanche, 20 parts of hawthorn, 0.5 part of steviol glycoside, food
Acceptable auxiliary material on product.
Its preparation method is:
A. specified volume raw material is weighed, is cleaned, it is standby;
B. black fruit fructus lycii is taken, is put into disintegrating machine and crushes, broken product, which are put into drier, vacuumizes 10min, squeezes the juice, filtering is obtained
Black fruit fructus lycii juice, 5 DEG C of sealings contain standby, and gained black fruit fructus lycii slag is collected standby;
C. saline cistanche is taken, is placed in historrhexis's machine and crushes, obtain saline cistanche fragment;
D. grape pip is taken, is placed in pulverizer and crushes, obtain grape pip powder and mince;
E. take above-mentioned black fruit fructus lycii slag, saline cistanche fragment, grape pip powder to mince, sanchi flower, hawthorn plus the immersion of 50 DEG C of water
30min, 70% edible alcohol is Extraction solvent, liquid ratio 10:1, extraction time 120min, ultrasonic power 200W, extraction temperature 50
DEG C, extract 3 times, obtain extract solution;
F. gained black fruit fructus lycii juice in step b is mixed with extract solution obtained by step e, stands 24h, filtering takes supernatant, dense
Contracting, 20% percentage by weight beta-schardinger dextrin is added in concentrate and is allocated, and is mixed, is obtained mixed liquor;
G. mixed liquor is preheated, is spray-dried, 180 DEG C of hot blast temperature, hot air flow 30m is adjusted3/ h, pan feeding flow
0.25L/h, get dry extract powder, adds steviol glycoside, mixes, produces solid beverage.
Or appropriate 70% edible ethanol will be added in the mixture of above-mentioned addition steviol glycoside, by " that holds is agglomerating, pinches i.e.
Dissipate " principle prepare softwood, be prepared into granule according to conventional process for producing granula.
Or the mixture of above-mentioned addition steviol glycoside is made into adhesive with 70% edible ethanol, prepared using boiling granulating method
Into particle, compressing tablet, piece agent.
With polyphenol content in the above-mentioned solid beverage of determined by ultraviolet spectrophotometry, it is 5.6% to measure polyphenol content.
Embodiment three
45 parts of black fruit fructus lycii, 70 parts of sanchi flower, 45 parts of grape pip, 60 parts of saline cistanche, 15 parts of hawthorn, 0.2 part of steviol glycoside, food
Upper acceptable auxiliary material.
Its preparation method is:
A. specified volume raw material is weighed, is cleaned, it is standby;
B. black fruit fructus lycii is taken, is put into disintegrating machine and crushes, broken product, which are put into drier, vacuumizes 8min, squeezes the juice, filtering is obtained
Black fruit fructus lycii juice, 4 DEG C of sealings contain standby, and gained black fruit fructus lycii slag is collected standby;
C. saline cistanche is taken, is placed in historrhexis's machine and crushes, obtain saline cistanche fragment;
D. grape pip is taken, is placed in pulverizer and crushes, obtain grape pip powder and mince;
E. take above-mentioned black fruit fructus lycii slag, saline cistanche fragment, grape pip powder to mince, sanchi flower, hawthorn plus the immersion of 45 DEG C of water
25min, 45% edible alcohol is Extraction solvent, liquid ratio 12:1, extraction time 90min, ultrasonic power 160W, extraction temperature 35
DEG C, extract 2 times, obtain extract solution;
F. gained black fruit fructus lycii juice in step b is mixed with extract solution obtained by step e, stands 20h, filtering takes supernatant, dense
Contracting, 15% percentage by weight beta-schardinger dextrin is added in concentrate and is allocated, and is mixed, is obtained mixed liquor;
G. mixed liquor is preheated, is spray-dried, 180 DEG C of hot blast temperature, hot air flow 28m is adjusted3/ h, pan feeding flow
0.20L/h, get dry extract powder, adds steviol glycoside, mixes, produces solid beverage.
Or appropriate 70% edible ethanol will be added in the mixture of above-mentioned addition steviol glycoside, by " that holds is agglomerating, pinches i.e.
Dissipate " principle prepare softwood, be prepared into granule according to conventional process for producing granula.
Or the mixture of above-mentioned addition steviol glycoside is made into adhesive with 70% edible ethanol, prepared using boiling granulating method
Into particle, compressing tablet, piece agent.
With polyphenol content in the above-mentioned solid beverage of determined by ultraviolet spectrophotometry, it is 5.9% to measure polyphenol content.
Example IV
35 parts of black fruit fructus lycii, 50 parts of sanchi flower, 40 parts of grape pip, 80 parts of saline cistanche, 12 parts of hawthorn, 0.4 part of steviol glycoside, food
Upper acceptable auxiliary material.
Its preparation method is:
A. specified volume raw material is weighed, is cleaned, it is standby;
B. black fruit fructus lycii is taken, is put into disintegrating machine and crushes, broken product, which are put into drier, vacuumizes 7min, squeezes the juice, filtering is obtained
Black fruit fructus lycii juice, 3 DEG C of sealings contain standby, and gained black fruit fructus lycii slag is collected standby;
C. saline cistanche is taken, is placed in historrhexis's machine and crushes, obtain saline cistanche fragment;
D. grape pip is taken, is placed in pulverizer and crushes, obtain grape pip powder and mince;
E. take above-mentioned black fruit fructus lycii slag, saline cistanche fragment, grape pip powder to mince, sanchi flower, hawthorn plus the immersion of 40 DEG C of water
20min, 50% edible alcohol is Extraction solvent, liquid ratio 15:1, extraction time 100min, ultrasonic power 180W, extraction temperature 40
DEG C, extract 1 time, obtain extract solution;
F. gained black fruit fructus lycii juice in step b is mixed with extract solution obtained by step e, stands 22h, filtering takes supernatant, dense
Contracting, 16% percentage by weight beta-schardinger dextrin is added in concentrate and is allocated, and is mixed, is obtained mixed liquor;
G. mixed liquor is preheated, is spray-dried, 180 DEG C of hot blast temperature, hot air flow 26m is adjusted3/ h, pan feeding flow
0.18L/h, get dry extract powder, adds steviol glycoside, mixes, produces solid beverage.
Or appropriate 70% edible ethanol will be added in the mixture of above-mentioned addition steviol glycoside, by " that holds is agglomerating, pinches i.e.
Dissipate " principle prepare softwood, be prepared into granule according to conventional process for producing granula.
Or the mixture of above-mentioned addition steviol glycoside is made into adhesive with 70% edible ethanol, prepared using boiling granulating method
Into particle, compressing tablet, piece agent.
To verify the synergy between each composition, on the basis of embodiment three, each side for reducing medicinal material simply is selected
Formula, is prepared into after preparation, compares experiment.
With polyphenol content in the above-mentioned solid beverage of determined by ultraviolet spectrophotometry, it is 5.5% to measure polyphenol content.
Embodiment five
70 parts of sanchi flower, 45 parts of grape pip, 60 parts of saline cistanche, 15 parts of hawthorn, 0.2 portion of steviol glycoside is acceptable auxiliary on food
Material.
Its preparation method is:
A. specified volume raw material is weighed, is cleaned, it is standby;
B. black fruit fructus lycii is taken, is put into disintegrating machine and crushes, broken product, which are put into drier, vacuumizes 8min, squeezes the juice, filtering is obtained
Black fruit fructus lycii juice, 4 DEG C of sealings contain standby, and gained black fruit fructus lycii slag is collected standby;
C. saline cistanche is taken, is placed in historrhexis's machine and crushes, obtain saline cistanche fragment;
D. grape pip is taken, is placed in pulverizer and crushes, obtain grape pip powder and mince;
E. take above-mentioned black fruit fructus lycii slag, saline cistanche fragment, grape pip powder to mince, sanchi flower, hawthorn plus the immersion of 45 DEG C of water
25min, 45% edible alcohol is Extraction solvent, liquid ratio 12:1, extraction time 90min, ultrasonic power 160W, extraction temperature 35
DEG C, extract 2 times, obtain extract solution;
F. gained black fruit fructus lycii juice in step b is mixed with extract solution obtained by step e, stands 20h, filtering takes supernatant, dense
Contracting, 15% percentage by weight beta-schardinger dextrin is added in concentrate and is allocated, and is mixed, is obtained mixed liquor;
G. mixed liquor is preheated, is spray-dried, 180 DEG C of hot blast temperature, hot air flow 28m is adjusted3/ h, pan feeding flow
0.20L/h, get dry extract powder, adds steviol glycoside, mixes, produces solid beverage.
With polyphenol content in the above-mentioned solid beverage of determined by ultraviolet spectrophotometry, it is 4.0% to measure polyphenol content.
Embodiment six
45 parts of black fruit fructus lycii, 45 parts of grape pip, 60 parts of saline cistanche, 15 parts of hawthorn, 0.2 portion of steviol glycoside is acceptable on food
Auxiliary material.
Its preparation method is:
A. specified volume raw material is weighed, is cleaned, it is standby;
B. black fruit fructus lycii is taken, is put into disintegrating machine and crushes, broken product, which are put into drier, vacuumizes 8min, squeezes the juice, filtering is obtained
Black fruit fructus lycii juice, 4 DEG C of sealings contain standby, and gained black fruit fructus lycii slag is collected standby;
C. saline cistanche is taken, is placed in historrhexis's machine and crushes, obtain saline cistanche fragment;
D. grape pip is taken, is placed in pulverizer and crushes, obtain grape pip powder and mince;
E. take above-mentioned black fruit fructus lycii slag, saline cistanche fragment, grape pip powder to mince, sanchi flower, hawthorn plus the immersion of 45 DEG C of water
25min, 45% edible alcohol is Extraction solvent, liquid ratio 12:1, extraction time 90min, ultrasonic power 160W, extraction temperature 35
DEG C, extract 2 times, obtain extract solution;
F. gained black fruit fructus lycii juice in step b is mixed with extract solution obtained by step e, stands 20h, filtering takes supernatant, dense
Contracting, 15% percentage by weight beta-schardinger dextrin is added in concentrate and is allocated, and is mixed, is obtained mixed liquor;
G. mixed liquor is preheated, is spray-dried, 180 DEG C of hot blast temperature, hot air flow 28m is adjusted3/ h, pan feeding flow
0.20L/h, get dry extract powder, adds steviol glycoside, mixes, produces solid beverage.
With polyphenol content in the above-mentioned solid beverage of determined by ultraviolet spectrophotometry, it is 3.8% to measure polyphenol content.
Embodiment seven
45 parts of black fruit fructus lycii, 70 parts of sanchi flower, 60 parts of saline cistanche, 15 parts of hawthorn, 0.2 portion of steviol glycoside is acceptable on food
Auxiliary material.
Its preparation method is:
A. specified volume raw material is weighed, is cleaned, it is standby;
B. black fruit fructus lycii is taken, is put into disintegrating machine and crushes, broken product, which are put into drier, vacuumizes 8min, squeezes the juice, filtering is obtained
Black fruit fructus lycii juice, 4 DEG C of sealings contain standby, and gained black fruit fructus lycii slag is collected standby;
C. saline cistanche is taken, is placed in historrhexis's machine and crushes, obtain saline cistanche fragment;
D. grape pip is taken, is placed in pulverizer and crushes, obtain grape pip powder and mince;
E. take above-mentioned black fruit fructus lycii slag, saline cistanche fragment, grape pip powder to mince, sanchi flower, hawthorn plus the immersion of 45 DEG C of water
25min, 45% edible alcohol is Extraction solvent, liquid ratio 12:1, extraction time 90min, ultrasonic power 160W, extraction temperature 35
DEG C, extract 2 times, obtain extract solution;
F. gained black fruit fructus lycii juice in step b is mixed with extract solution obtained by step e, stands 20h, filtering takes supernatant, dense
Contracting, 15% percentage by weight beta-schardinger dextrin is added in concentrate and is allocated, and is mixed, is obtained mixed liquor;
G. mixed liquor is preheated, is spray-dried, 180 DEG C of hot blast temperature, hot air flow 28m is adjusted3/ h, pan feeding flow
0.20L/h, get dry extract powder, adds steviol glycoside, mixes, produces solid beverage.
With polyphenol content in the above-mentioned solid beverage of determined by ultraviolet spectrophotometry, it is 4.2% to measure polyphenol content.
Embodiment eight
45 parts of black fruit fructus lycii, 70 parts of sanchi flower, 45 parts of grape pip, 15 parts of hawthorn, 0.2 portion of steviol glycoside is acceptable on food
Auxiliary material.
Its preparation method is:
A. specified volume raw material is weighed, is cleaned, it is standby;
B. black fruit fructus lycii is taken, is put into disintegrating machine and crushes, broken product, which are put into drier, vacuumizes 8min, squeezes the juice, filtering is obtained
Black fruit fructus lycii juice, 4 DEG C of sealings contain standby, and gained black fruit fructus lycii slag is collected standby;
C. saline cistanche is taken, is placed in historrhexis's machine and crushes, obtain saline cistanche fragment;
D. grape pip is taken, is placed in pulverizer and crushes, obtain grape pip powder and mince;
E. take above-mentioned black fruit fructus lycii slag, saline cistanche fragment, grape pip powder to mince, sanchi flower, hawthorn plus the immersion of 45 DEG C of water
25min, 45% edible alcohol is Extraction solvent, liquid ratio 12:1, extraction time 90min, ultrasonic power 160W, extraction temperature 35
DEG C, extract 2 times, obtain extract solution;
F. gained black fruit fructus lycii juice in step b is mixed with extract solution obtained by step e, stands 20h, filtering takes supernatant, dense
Contracting, 15% percentage by weight beta-schardinger dextrin is added in concentrate and is allocated, and is mixed, is obtained mixed liquor;
G. mixed liquor is preheated, is spray-dried, 180 DEG C of hot blast temperature, hot air flow 28m is adjusted3/ h, pan feeding flow
0.20L/h, get dry extract powder, adds steviol glycoside, mixes, produces solid beverage.
With polyphenol content in the above-mentioned solid beverage of determined by ultraviolet spectrophotometry, it is 4.2% to measure polyphenol content.
Embodiment nine
45 parts of black fruit fructus lycii, 70 parts of sanchi flower, 45 parts of grape pip, 60 parts of saline cistanche, 0.2 portion of steviol glycoside is subjected on food
Auxiliary material.
Its preparation method is:
A. specified volume raw material is weighed, is cleaned, it is standby;
B. black fruit fructus lycii is taken, is put into disintegrating machine and crushes, broken product, which are put into drier, vacuumizes 8min, squeezes the juice, filtering is obtained
Black fruit fructus lycii juice, 4 DEG C of sealings contain standby, and gained black fruit fructus lycii slag is collected standby;
C. saline cistanche is taken, is placed in historrhexis's machine and crushes, obtain saline cistanche fragment;
D. grape pip is taken, is placed in pulverizer and crushes, obtain grape pip powder and mince;
E. take above-mentioned black fruit fructus lycii slag, saline cistanche fragment, grape pip powder to mince, sanchi flower, hawthorn plus the immersion of 45 DEG C of water
25min, 45% edible alcohol is Extraction solvent, liquid ratio 12:1, extraction time 90min, ultrasonic power 160W, extraction temperature 35
DEG C, extract 2 times, obtain extract solution;
F. gained black fruit fructus lycii juice in step b is mixed with extract solution obtained by step e, stands 20h, filtering takes supernatant, dense
Contracting, 15% percentage by weight beta-schardinger dextrin is added in concentrate and is allocated, and is mixed, is obtained mixed liquor;
G. mixed liquor is preheated, is spray-dried, 180 DEG C of hot blast temperature, hot air flow 28m is adjusted3/ h, pan feeding flow
0.20L/h, get dry extract powder, adds steviol glycoside, mixes, produces solid beverage.
With polyphenol content in the above-mentioned solid beverage of determined by ultraviolet spectrophotometry, it is 4.8% to measure polyphenol content.
Embodiment ten
Using above-described embodiment three, embodiment five, embodiment six, embodiment seven, embodiment eight, the gained solid beverage of embodiment nine
For experimental group, antioxidation in vitro experiment, lipid-lowering test, hypotensive experiment, sleeping experiment are carried out.
1. solid beverage antioxidation in vitro experiment influence of the present invention
Assay method reference:Xiong Hejian, Zheng Jianhua, Wu Guohong etc., the separation of lichee polyphenol prepares and removed DPPH activity [J]
Food Science, 2006,27(7):86-88.Measurement result is as follows:
The DPPH free radical scavenging activities of table 1(%)
Experimental result confirms that, as concentration increases, experimental group and control group oxidation resistance are significantly increased;Implement with concentration
The products obtained therefrom oxidation resistance of example three is better than other embodiment group and control group;Illustrate that there is certain association in composition between each component
Same-action, compatibility using improving product oxidation resistance to a certain extent.
2. influence of the solid beverage of the present invention to the amobarbital inducing mouse length of one's sleep
Assay method reference:Huang Wei, Jin Bangquan, Cheng Guangyu etc., spina date seed functional component determine and improved sleep health function
Study precious traditional Chinese medical science traditional Chinese medicines, 2008,19 during [J](5):1173-1175.Measurement result is as follows:
The influence of 2 pairs of extension amobarbital inducing mouse lengths of one's sleep of table( s)
* compared that there were significant differences with blank group(P<0.05)
Influence of 3 solid beverages of table to voluntary tested crowd's sleep incidence
Experimental result confirms that product of the present invention can extend the length of one's sleep, is voluntarily shown that the product can improve sleep hair by test result
Raw rate, there is certain sleeping effect.
3. the hypoglycemic experimental result of solid beverage of the present invention
Assay method reference:Shi Yutao, Yu Zhi, Chen Yuqiong etc., comparison [J] Central China agricultures of 2 kinds of Tea Polysaccharides blood sugar decreasing effects
Industry college journal, 2015,34(2):113-119.Measurement result is as follows, and wherein model group is through diabetic animal modeling:
The solid beverage of table 4 is to model mice hypoglycemic effect( s)
* is compared with blank group, and there were significant differences(P<0.01)
Experimental result confirms that product of the present invention can effectively reduce experimental animal blood glucose value, and embodiment three and other group of result
Compare, illustrate there is certain synergy between each component.
4. acute oral toxicity test result:To the maximum tolerated dose of female, male Kunming mouse(MTD)It is all higher than
20.0 mL/kg body weight, belong to nontoxic level.
5. three genetic toxicity test results:Salmonella reversion test, mice bone marrow micronucleus, mouse essence
Sub- deformity result of the test is feminine gender.
6. 30 days feeding trial results:With 1.7mL/kg body weight, 3.3mL/kg body weight, 6.7mL/kg body weight agent
The product rat oral gavage of amount 30 days, as a result shows, animal growth is good, each dosage group body weight, weightening, food utilization, blood
Conventional index, blood biochemistry index, organ weights and internal organs/body weight ratio are compared with control group, and there was no significant difference, gross anatomy
The abnormal change relevant with sample is had no with tissue pathology checking.
Claims (8)
1. a kind of beverage composition for treating dental erosion, it is characterised in that it is composed of the following raw materials by weight:10-50 parts of black fruit fructus lycii, sanchi flower
30-80 parts, 10-50 parts of grape pip, 50-100 parts of saline cistanche, 10-20 parts of hawthorn, 0.1-0.5 portions of steviol glycoside can connect on food
The auxiliary material received.
2. a kind of beverage composition for treating dental erosion according to claim 1, it is characterised in that it is composed of the following raw materials by weight:It is black
45 parts of fruit matrimony vine, 70 parts of sanchi flower, 45 parts of grape pip, 60 parts of saline cistanche, 15 parts of hawthorn, 0.2 portion of steviol glycoside can connect on food
The auxiliary material received.
3. the preparation method of a kind of beverage composition for treating dental erosion according to claim 1 or claim 2, it is characterised in that be prepared into beverage
Preparation method is as follows:
A. specified volume raw material is weighed, is cleaned, it is standby;
B. black fruit fructus lycii is taken, is put into disintegrating machine and crushes, broken product, which are put into drier, vacuumizes 5-10min, squeezes the juice, filtering,
Black fruit fructus lycii juice is obtained, 2-5 DEG C of sealing contains standby, gained black fruit fructus lycii slag is collected standby;
C. saline cistanche is taken, is placed in historrhexis's machine and crushes, obtain saline cistanche fragment;
D. grape pip is taken, is placed in pulverizer and crushes, obtain grape pip powder and mince;
E. take above-mentioned black fruit fructus lycii slag, saline cistanche fragment, grape pip powder to mince, sanchi flower, hawthorn plus the immersion of 30-50 DEG C of water
15-30min, 30-70% edible alcohol are Extraction solvent, liquid ratio 20-10:1, extraction time 60-120min, ultrasonic power 80-
200W, 30-50 DEG C of extraction temperature extracts 1-3 times, obtains extract solution;
F. gained black fruit fructus lycii juice in step b is mixed with extract solution obtained by step e, stands 16-24h, filtering takes supernatant,
Concentration, addition 10-20% percentage by weight beta-schardinger dextrins are allocated in concentrate, are mixed, are obtained mixed liquor;
G. mixed liquor is preheated, is spray-dried, 180~200 DEG C of hot blast temperature, 25~30m of hot air flow is adjusted3/ h, pan feeding
0.15~0.25L/h of flow, get dry extract powder.
4. a kind of preparation method of beverage composition for treating dental erosion according to claim 3, it is characterised in that:
(1)In step b, the pumpdown time is 7-8min, is squeezed the juice, and sealing contains temperature for 3-5 DEG C;
(2)In step e, plus 30-35 DEG C of water immersion 15-20min, 40-50% edible alcohols are Extraction solvent, liquid ratio 18-15:
1, extraction time 60-90min, ultrasonic power 100-150W, 35-45 DEG C of extraction temperature are extracted 1-2 times;
(3)In step f, time of repose is 18-20h, and beta-schardinger dextrin addition is 12-16% percentage by weights;
(4)In step g, preheating temperature is 60-80 DEG C, 185~195 DEG C of hot blast temperature, 26~28m of hot air flow3/ h, enters stream
Measure 0.18~0.22L/h.
5. application of the beverage composition for treating dental erosion as claimed in claim 1 or 2 in health products, food or specific use beverage is prepared.
6. the application of beverage composition for treating dental erosion as claimed in claim 5, the purposes includes hypoglycemic, improvement sleep.
7. the application of beverage composition for treating dental erosion as claimed in claim 6, it is characterised in that the food or health products are granule, piece
Agent, powder, oral liquid formulation.
8. a kind of quality determining method of beverage composition for treating dental erosion, it is characterised in that preparation method is made as described in claim 3 or 4
Product, be not less than 5% with determined by ultraviolet spectrophotometry Determination of Polyphenols.
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109966422A (en) * | 2019-03-26 | 2019-07-05 | 渭源县会源药业有限公司 | A kind of desert cistanche lily blood-sugar reducing tea and preparation method thereof |
CN112262937A (en) * | 2020-10-26 | 2021-01-26 | 武汉职业技术学院 | Cistanche compound beverage and preparation method thereof |
Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10150824A1 (en) * | 2001-10-15 | 2003-07-17 | Wild Gmbh & Co Kg Rudolf | Concentrate, its manufacture and use |
CN102423437A (en) * | 2011-12-27 | 2012-04-25 | 峨眉山天梁星制药有限公司 | Double-prescription medicament for treating apoplectic hemiplegia and preparation method thereof |
CN102703296A (en) * | 2012-05-29 | 2012-10-03 | 宁夏农林科学院 | Lycium ruthenicum health-care wine |
CN103330119A (en) * | 2013-06-07 | 2013-10-02 | 青岛银龄美海洋生物科技有限公司 | Health-care food for accessorily reducing blood fat |
CN105707873A (en) * | 2016-04-06 | 2016-06-29 | 黄汉 | Health-care product composition containing procyanidine and preparation method of health-care product composition |
CN105995711A (en) * | 2016-05-25 | 2016-10-12 | 丽江格林斯通食品有限公司 | Fructus phyllanthi compound preparation and preparation method thereof |
CN106261236A (en) * | 2016-08-12 | 2017-01-04 | 山东琪琪食品有限公司 | A kind of fruit pectin beverage and production method thereof |
CN106490611A (en) * | 2016-10-20 | 2017-03-15 | 陆小平 | A kind of Radix Notoginseng flower composition and its preparation method and application |
-
2017
- 2017-05-02 CN CN201710302406.9A patent/CN106942561A/en active Pending
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10150824A1 (en) * | 2001-10-15 | 2003-07-17 | Wild Gmbh & Co Kg Rudolf | Concentrate, its manufacture and use |
CN102423437A (en) * | 2011-12-27 | 2012-04-25 | 峨眉山天梁星制药有限公司 | Double-prescription medicament for treating apoplectic hemiplegia and preparation method thereof |
CN102703296A (en) * | 2012-05-29 | 2012-10-03 | 宁夏农林科学院 | Lycium ruthenicum health-care wine |
CN103330119A (en) * | 2013-06-07 | 2013-10-02 | 青岛银龄美海洋生物科技有限公司 | Health-care food for accessorily reducing blood fat |
CN105707873A (en) * | 2016-04-06 | 2016-06-29 | 黄汉 | Health-care product composition containing procyanidine and preparation method of health-care product composition |
CN105995711A (en) * | 2016-05-25 | 2016-10-12 | 丽江格林斯通食品有限公司 | Fructus phyllanthi compound preparation and preparation method thereof |
CN106261236A (en) * | 2016-08-12 | 2017-01-04 | 山东琪琪食品有限公司 | A kind of fruit pectin beverage and production method thereof |
CN106490611A (en) * | 2016-10-20 | 2017-03-15 | 陆小平 | A kind of Radix Notoginseng flower composition and its preparation method and application |
Non-Patent Citations (1)
Title |
---|
张保国: "《精选男性药酒1200例》", 31 May 2013, 中国医药科技出版社 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109966422A (en) * | 2019-03-26 | 2019-07-05 | 渭源县会源药业有限公司 | A kind of desert cistanche lily blood-sugar reducing tea and preparation method thereof |
CN112262937A (en) * | 2020-10-26 | 2021-01-26 | 武汉职业技术学院 | Cistanche compound beverage and preparation method thereof |
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