CN101253903B - Health food with fat-reducing function and its preparation - Google Patents
Health food with fat-reducing function and its preparation Download PDFInfo
- Publication number
- CN101253903B CN101253903B CN2008101035074A CN200810103507A CN101253903B CN 101253903 B CN101253903 B CN 101253903B CN 2008101035074 A CN2008101035074 A CN 2008101035074A CN 200810103507 A CN200810103507 A CN 200810103507A CN 101253903 B CN101253903 B CN 101253903B
- Authority
- CN
- China
- Prior art keywords
- extract
- health food
- dry extract
- fat
- weight
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000002360 preparation method Methods 0.000 title claims abstract description 14
- 235000013402 health food Nutrition 0.000 title claims description 48
- 239000003814 drug Substances 0.000 claims abstract description 40
- 229940079593 drugs Drugs 0.000 claims abstract description 27
- 241001122767 Theaceae Species 0.000 claims abstract description 19
- 235000013616 tea Nutrition 0.000 claims abstract description 19
- 235000006468 Thea sinensis Nutrition 0.000 claims abstract description 17
- 235000020333 oolong tea Nutrition 0.000 claims abstract description 17
- 235000008599 Poria cocos Nutrition 0.000 claims abstract description 15
- 239000000284 extract Substances 0.000 claims description 74
- 240000002853 Nelumbo nucifera Species 0.000 claims description 24
- 239000000843 powder Substances 0.000 claims description 24
- 235000006508 Nelumbo nucifera Nutrition 0.000 claims description 23
- 235000006510 Nelumbo pentapetala Nutrition 0.000 claims description 23
- 240000005373 Panax quinquefolius Species 0.000 claims description 21
- 240000002234 Allium sativum Species 0.000 claims description 20
- 235000003140 Panax quinquefolius Nutrition 0.000 claims description 20
- 235000004611 garlic Nutrition 0.000 claims description 20
- ZMJBYMUCKBYSCP-UHFFFAOYSA-N Hibiscus acid Chemical compound OC(=O)C(O)C(O)(C(O)=O)CC(O)=O ZMJBYMUCKBYSCP-UHFFFAOYSA-N 0.000 claims description 15
- 229920002752 Konjac Polymers 0.000 claims description 15
- 240000001313 Lycium barbarum Species 0.000 claims description 15
- 244000197580 Poria cocos Species 0.000 claims description 15
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 15
- 229940089491 hydroxycitric acid Drugs 0.000 claims description 15
- 238000005303 weighing Methods 0.000 claims description 15
- 235000007516 Chrysanthemum Nutrition 0.000 claims description 14
- 235000005986 Chrysanthemum x morifolium Nutrition 0.000 claims description 14
- 235000015459 Lycium barbarum Nutrition 0.000 claims description 14
- 240000004678 Panax pseudoginseng Species 0.000 claims description 14
- 235000003181 Panax pseudoginseng Nutrition 0.000 claims description 14
- 235000017423 hawthorn Nutrition 0.000 claims description 14
- 235000016855 Biancospino Nutrition 0.000 claims description 13
- 240000007646 Chrysanthemum x morifolium Species 0.000 claims description 13
- 235000017181 Crataegus chrysocarpa Nutrition 0.000 claims description 13
- 235000004423 Crataegus monogyna Nutrition 0.000 claims description 13
- 235000002313 hawthorn Nutrition 0.000 claims description 13
- 235000009444 hawthorn Nutrition 0.000 claims description 13
- 235000009486 hawthorn Nutrition 0.000 claims description 13
- 235000009682 hawthorn Nutrition 0.000 claims description 13
- 235000009685 hawthorn Nutrition 0.000 claims description 13
- 235000009917 hawthorn Nutrition 0.000 claims description 13
- 235000013161 hawthorn Nutrition 0.000 claims description 13
- 235000013165 hawthorn Nutrition 0.000 claims description 13
- 235000013189 hawthorn Nutrition 0.000 claims description 13
- 235000013204 hawthorn Nutrition 0.000 claims description 13
- 235000013214 hawthorn Nutrition 0.000 claims description 13
- 235000013246 hawthorn Nutrition 0.000 claims description 13
- 239000007901 soft capsule Substances 0.000 claims description 12
- 239000000796 flavoring agent Substances 0.000 claims description 11
- 235000019634 flavors Nutrition 0.000 claims description 11
- 239000012141 concentrate Substances 0.000 claims description 6
- 239000012153 distilled water Substances 0.000 claims description 4
- 239000000203 mixture Substances 0.000 claims description 4
- 238000002156 mixing Methods 0.000 claims description 3
- 238000007796 conventional method Methods 0.000 claims description 2
- 238000009472 formulation Methods 0.000 claims description 2
- 240000000171 Crataegus monogyna Species 0.000 claims 3
- 208000008589 Obesity Diseases 0.000 abstract description 29
- 241000180649 Panax notoginseng Species 0.000 abstract description 5
- 235000003143 Panax notoginseng Nutrition 0.000 abstract description 4
- 239000004480 active ingredient Substances 0.000 abstract description 4
- 241000049624 Alisma plantago-aquatica subsp. orientale Species 0.000 abstract description 2
- 241001465754 Metazoa Species 0.000 abstract description 2
- 238000002474 experimental method Methods 0.000 abstract description 2
- 235000001497 healthy food Nutrition 0.000 abstract 4
- 240000001754 Peltandra virginica Species 0.000 abstract 1
- 235000001188 Peltandra virginica Nutrition 0.000 abstract 1
- 230000000694 effects Effects 0.000 description 30
- 235000020824 obesity Nutrition 0.000 description 28
- 230000037396 body weight Effects 0.000 description 27
- 235000013305 food Nutrition 0.000 description 20
- 230000036541 health Effects 0.000 description 20
- 210000004369 Blood Anatomy 0.000 description 18
- 239000008280 blood Substances 0.000 description 18
- 235000005911 diet Nutrition 0.000 description 13
- HVYWMOMLDIMFJA-DPAQBDIFSA-N (3β)-Cholest-5-en-3-ol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 10
- 241001092040 Crataegus Species 0.000 description 10
- 239000002253 acid Substances 0.000 description 10
- 210000000577 Adipose Tissue Anatomy 0.000 description 9
- 241000700159 Rattus Species 0.000 description 9
- 150000003626 triacylglycerols Chemical class 0.000 description 9
- 210000000952 Spleen Anatomy 0.000 description 8
- 210000004027 cells Anatomy 0.000 description 8
- 230000037213 diet Effects 0.000 description 8
- 201000010099 disease Diseases 0.000 description 8
- 206010012735 Diarrhoea Diseases 0.000 description 7
- 230000036740 Metabolism Effects 0.000 description 7
- 210000002784 Stomach Anatomy 0.000 description 7
- 125000001931 aliphatic group Chemical group 0.000 description 7
- 238000004519 manufacturing process Methods 0.000 description 7
- 230000004060 metabolic process Effects 0.000 description 7
- 230000035786 metabolism Effects 0.000 description 7
- 210000001789 adipocyte Anatomy 0.000 description 6
- 239000000463 material Substances 0.000 description 6
- 239000002994 raw material Substances 0.000 description 6
- 229940107161 Cholesterol Drugs 0.000 description 5
- 206010062060 Hyperlipidaemia Diseases 0.000 description 5
- 206010020772 Hypertension Diseases 0.000 description 5
- 210000003734 Kidney Anatomy 0.000 description 5
- 210000004185 Liver Anatomy 0.000 description 5
- 238000010521 absorption reaction Methods 0.000 description 5
- 230000001058 adult Effects 0.000 description 5
- 230000003579 anti-obesity Effects 0.000 description 5
- 230000000378 dietary Effects 0.000 description 5
- 230000029087 digestion Effects 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- 235000015097 nutrients Nutrition 0.000 description 5
- WQZGKKKJIJFFOK-GASJEMHNSA-N D-Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 4
- 210000002966 Serum Anatomy 0.000 description 4
- 238000009825 accumulation Methods 0.000 description 4
- 239000002775 capsule Substances 0.000 description 4
- 235000012000 cholesterol Nutrition 0.000 description 4
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 4
- 235000009508 confectionery Nutrition 0.000 description 4
- 235000013399 edible fruits Nutrition 0.000 description 4
- 239000008103 glucose Substances 0.000 description 4
- 230000012010 growth Effects 0.000 description 4
- 230000002265 prevention Effects 0.000 description 4
- 235000021251 pulses Nutrition 0.000 description 4
- 150000007949 saponins Chemical class 0.000 description 4
- 235000017709 saponins Nutrition 0.000 description 4
- -1 sulfide compound Chemical class 0.000 description 4
- 230000000007 visual effect Effects 0.000 description 4
- PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical compound C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 description 3
- 102000004146 ATP citrate synthases Human genes 0.000 description 3
- 108090000662 ATP citrate synthases Proteins 0.000 description 3
- 206010000060 Abdominal distension Diseases 0.000 description 3
- 210000001367 Arteries Anatomy 0.000 description 3
- 208000002173 Dizziness Diseases 0.000 description 3
- 241000196324 Embryophyta Species 0.000 description 3
- 229940096919 Glycogen Drugs 0.000 description 3
- 229920002527 Glycogen Polymers 0.000 description 3
- BYSGBSNPRWKUQH-UJDJLXLFSA-N Glycogen Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1OC[C@@H]1[C@@H](O[C@@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)O)[C@H](O)[C@@H](O)[C@@H](O[C@@H]2[C@H](O[C@H](O)[C@H](O)[C@H]2O)CO)O1 BYSGBSNPRWKUQH-UJDJLXLFSA-N 0.000 description 3
- 241000283973 Oryctolagus cuniculus Species 0.000 description 3
- 206010033307 Overweight Diseases 0.000 description 3
- 208000002193 Pain Diseases 0.000 description 3
- 208000004880 Polyuria Diseases 0.000 description 3
- 210000002700 Urine Anatomy 0.000 description 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 3
- 230000036772 blood pressure Effects 0.000 description 3
- 150000001720 carbohydrates Chemical class 0.000 description 3
- 235000014633 carbohydrates Nutrition 0.000 description 3
- 230000035619 diuresis Effects 0.000 description 3
- 239000002552 dosage form Substances 0.000 description 3
- 238000001035 drying Methods 0.000 description 3
- 201000005577 familial hyperlipidemia Diseases 0.000 description 3
- 230000004634 feeding behavior Effects 0.000 description 3
- 230000037356 lipid metabolism Effects 0.000 description 3
- 150000002632 lipids Chemical class 0.000 description 3
- 235000020825 overweight Nutrition 0.000 description 3
- 230000000144 pharmacologic effect Effects 0.000 description 3
- 230000025627 positive regulation of urine volume Effects 0.000 description 3
- 239000001397 quillaja saponaria molina bark Substances 0.000 description 3
- 238000010998 test method Methods 0.000 description 3
- 230000001256 tonic Effects 0.000 description 3
- 235000015961 tonic Nutrition 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- SFLSHLFXELFNJZ-QMMMGPOBSA-N (-)-norepinephrine Chemical compound NC[C@H](O)C1=CC=C(O)C(O)=C1 SFLSHLFXELFNJZ-QMMMGPOBSA-N 0.000 description 2
- TWNIBLMWSKIRAT-RWOPYEJCSA-N (1R,2S,3S,4S,5R)-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol Chemical group O1[C@@]2([H])OC[C@]1([H])[C@@H](O)[C@H](O)[C@@H]2O TWNIBLMWSKIRAT-RWOPYEJCSA-N 0.000 description 2
- JDLKFOPOAOFWQN-VIFPVBQESA-N Allicin Natural products C=CCS[S@](=O)CC=C JDLKFOPOAOFWQN-VIFPVBQESA-N 0.000 description 2
- UFLHIIWVXFIJGU-ARJAWSKDSA-N Cis-3-Hexen-1-ol Chemical compound CC\C=C/CCO UFLHIIWVXFIJGU-ARJAWSKDSA-N 0.000 description 2
- 208000004981 Coronary Disease Diseases 0.000 description 2
- 108010036824 EC 4.1.3.6 Proteins 0.000 description 2
- 206010016256 Fatigue Diseases 0.000 description 2
- PWAOOJDMFUQOKB-ZSMJKITDSA-N Ginsenoside Re Natural products O([C@](CC/C=C(\C)/C)(C)[C@@H]1[C@H]2[C@@H](O)C[C@H]3[C@](C)([C@]2(C)CC1)C[C@H](O[C@@H]1[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](O)[C@H](C)O2)[C@@H](O)[C@H](O)[C@@H](CO)O1)[C@H]1C(C)(C)[C@@H](O)CC[C@]31C)[C@H]1[C@@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 PWAOOJDMFUQOKB-ZSMJKITDSA-N 0.000 description 2
- 206010018987 Haemorrhage Diseases 0.000 description 2
- 210000001624 Hip Anatomy 0.000 description 2
- 229940088597 Hormone Drugs 0.000 description 2
- 206010062717 Increased upper airway secretion Diseases 0.000 description 2
- 206010021703 Indifference Diseases 0.000 description 2
- 210000003127 Knee Anatomy 0.000 description 2
- SFLSHLFXELFNJZ-MRVPVSSYSA-N L-Noradrenaline Natural products NC[C@@H](O)C1=CC=C(O)C(O)=C1 SFLSHLFXELFNJZ-MRVPVSSYSA-N 0.000 description 2
- 210000004072 Lung Anatomy 0.000 description 2
- 108020004999 Messenger RNA Proteins 0.000 description 2
- 229960002748 Norepinephrine Drugs 0.000 description 2
- 206010030113 Oedema Diseases 0.000 description 2
- 229920002472 Starch Polymers 0.000 description 2
- 240000008042 Zea mays Species 0.000 description 2
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 2
- 239000003513 alkali Substances 0.000 description 2
- 230000000844 anti-bacterial Effects 0.000 description 2
- 239000002830 appetite depressant Substances 0.000 description 2
- 239000007864 aqueous solution Substances 0.000 description 2
- 230000003143 atherosclerotic Effects 0.000 description 2
- 230000006399 behavior Effects 0.000 description 2
- UHOVQNZJYSORNB-UHFFFAOYSA-N benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 2
- 230000033228 biological regulation Effects 0.000 description 2
- 230000000740 bleeding Effects 0.000 description 2
- 231100000319 bleeding Toxicity 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 210000000038 chest Anatomy 0.000 description 2
- 235000005822 corn Nutrition 0.000 description 2
- 235000005824 corn Nutrition 0.000 description 2
- 201000008739 coronary artery disease Diseases 0.000 description 2
- 201000008286 diarrhea Diseases 0.000 description 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
- 235000021271 drinking Nutrition 0.000 description 2
- 230000035622 drinking Effects 0.000 description 2
- 230000003203 everyday Effects 0.000 description 2
- 235000008216 herbs Nutrition 0.000 description 2
- 239000005556 hormone Substances 0.000 description 2
- 238000005213 imbibition Methods 0.000 description 2
- 238000000338 in vitro Methods 0.000 description 2
- 230000002401 inhibitory effect Effects 0.000 description 2
- 238000007689 inspection Methods 0.000 description 2
- 235000012054 meals Nutrition 0.000 description 2
- 230000003340 mental Effects 0.000 description 2
- 229920002106 messenger RNA Polymers 0.000 description 2
- 230000027939 micturition Effects 0.000 description 2
- PVNIIMVLHYAWGP-UHFFFAOYSA-N nicotinic acid Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 description 2
- 235000016709 nutrition Nutrition 0.000 description 2
- 230000001737 promoting Effects 0.000 description 2
- 230000005180 public health Effects 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 230000033764 rhythmic process Effects 0.000 description 2
- QZAYGJVTTNCVMB-UHFFFAOYSA-N serotonin Chemical compound C1=C(O)C=C2C(CCN)=CNC2=C1 QZAYGJVTTNCVMB-UHFFFAOYSA-N 0.000 description 2
- 231100000486 side effect Toxicity 0.000 description 2
- 230000007958 sleep Effects 0.000 description 2
- 235000019698 starch Nutrition 0.000 description 2
- 239000008107 starch Substances 0.000 description 2
- 238000005728 strengthening Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 230000001629 suppression Effects 0.000 description 2
- 230000002522 swelling Effects 0.000 description 2
- 238000002560 therapeutic procedure Methods 0.000 description 2
- 235000013311 vegetables Nutrition 0.000 description 2
- 239000000341 volatile oil Substances 0.000 description 2
- 235000019786 weight gain Nutrition 0.000 description 2
- FBFMBWCLBGQEBU-RXMALORBSA-N (2S,3R,4S,5S,6R)-2-[(2R,3R,4S,5S,6R)-2-[[(3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-3,12-dihydroxy-4,4,8,10,14-pentamethyl-17-[(2S)-6-methyl-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhept-5-en-2-yl]-2,3,5,6,7,9,11,12,13,15,16,17-dodecah Chemical compound O([C@@](C)(CCC=C(C)C)[C@@H]1[C@@H]2[C@@]([C@@]3(C[C@@H]([C@H]4C(C)(C)[C@@H](O)CC[C@]4(C)[C@H]3C[C@H]2O)O[C@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)O[C@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)O)C)(C)CC1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O FBFMBWCLBGQEBU-RXMALORBSA-N 0.000 description 1
- KWTSXDURSIMDCE-QMMMGPOBSA-N (S)-amphetamine Chemical compound C[C@H](N)CC1=CC=CC=C1 KWTSXDURSIMDCE-QMMMGPOBSA-N 0.000 description 1
- MGBKJKDRMRAZKC-UHFFFAOYSA-N 3-aminobenzene-1,2-diol Chemical compound NC1=CC=CC(O)=C1O MGBKJKDRMRAZKC-UHFFFAOYSA-N 0.000 description 1
- 241000209514 Alismataceae Species 0.000 description 1
- 206010001928 Amenorrhoea Diseases 0.000 description 1
- 229940025084 Amphetamine Drugs 0.000 description 1
- KYLIZBIRMBGUOP-UHFFFAOYSA-N Anethole trithione Chemical group C1=CC(OC)=CC=C1C1=CC(=S)SS1 KYLIZBIRMBGUOP-UHFFFAOYSA-N 0.000 description 1
- 241000208340 Araliaceae Species 0.000 description 1
- 240000007124 Brassica oleracea Species 0.000 description 1
- 235000011301 Brassica oleracea var capitata Nutrition 0.000 description 1
- 235000001169 Brassica oleracea var oleracea Nutrition 0.000 description 1
- 206010006326 Breath odour Diseases 0.000 description 1
- 241000282461 Canis lupus Species 0.000 description 1
- 241000131317 Capitulum Species 0.000 description 1
- 240000008574 Capsicum frutescens Species 0.000 description 1
- PHIQHXFUZVPYII-UHFFFAOYSA-N Carnitine Chemical compound C[N+](C)(C)CC(O)CC([O-])=O PHIQHXFUZVPYII-UHFFFAOYSA-N 0.000 description 1
- 240000005250 Chrysanthemum indicum Species 0.000 description 1
- 235000008495 Chrysanthemum leucanthemum Nutrition 0.000 description 1
- 244000192528 Chrysanthemum parthenium Species 0.000 description 1
- 235000000604 Chrysanthemum parthenium Nutrition 0.000 description 1
- 206010010774 Constipation Diseases 0.000 description 1
- 210000004351 Coronary Vessels Anatomy 0.000 description 1
- 210000000028 Corpus adiposum pararenale Anatomy 0.000 description 1
- 241000657480 Crataegus pinnatifida Species 0.000 description 1
- 241000721047 Danaus plexippus Species 0.000 description 1
- 206010012601 Diabetes mellitus Diseases 0.000 description 1
- 241000668709 Dipterocarpus costatus Species 0.000 description 1
- 206010013954 Dysphoria Diseases 0.000 description 1
- 206010014080 Ecchymosis Diseases 0.000 description 1
- 210000002969 Egg Yolk Anatomy 0.000 description 1
- 229940088598 Enzyme Drugs 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 208000010228 Erectile Dysfunction Diseases 0.000 description 1
- 210000003414 Extremities Anatomy 0.000 description 1
- 210000002468 Fat Body Anatomy 0.000 description 1
- 229960001582 Fenfluramine Drugs 0.000 description 1
- 235000019733 Fish meal Nutrition 0.000 description 1
- 210000004392 Genitalia Anatomy 0.000 description 1
- JDCPEKQWFDWQLI-BSBOBSSASA-N Ginsenoside Rc Natural products O([C@](CC/C=C(\C)/C)(C)[C@@H]1[C@H]2[C@H](O)C[C@H]3[C@](C)([C@]2(C)CC1)CC[C@H]1C(C)(C)[C@@H](O[C@H]2[C@H](O[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O4)[C@@H](O)[C@H](O)[C@@H](CO)O2)CC[C@]31C)[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO[C@H]2[C@H](O)[C@H](O)[C@H](CO)O2)O1 JDCPEKQWFDWQLI-BSBOBSSASA-N 0.000 description 1
- 102000018997 Growth Hormone Human genes 0.000 description 1
- 108010051696 Growth Hormone Proteins 0.000 description 1
- 206010018836 Haematochezia Diseases 0.000 description 1
- 210000003128 Head Anatomy 0.000 description 1
- 206010019233 Headache Diseases 0.000 description 1
- 210000002216 Heart Anatomy 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 210000003016 Hypothalamus Anatomy 0.000 description 1
- 206010061598 Immunodeficiency Diseases 0.000 description 1
- 206010022114 Injury Diseases 0.000 description 1
- 206010022437 Insomnia Diseases 0.000 description 1
- 210000000936 Intestines Anatomy 0.000 description 1
- 206010022998 Irritability Diseases 0.000 description 1
- 206010027339 Menstruation irregular Diseases 0.000 description 1
- 208000001022 Morbid Obesity Diseases 0.000 description 1
- 210000000214 Mouth Anatomy 0.000 description 1
- 210000003205 Muscles Anatomy 0.000 description 1
- 206010028813 Nausea Diseases 0.000 description 1
- 210000000826 Nictitating Membrane Anatomy 0.000 description 1
- DBGIVFWFUFKIQN-UHFFFAOYSA-N Obedrex Chemical compound CCNC(C)CC1=CC=CC(C(F)(F)F)=C1 DBGIVFWFUFKIQN-UHFFFAOYSA-N 0.000 description 1
- 206010030302 Oliguria Diseases 0.000 description 1
- LPMXVESGRSUGHW-HBYQJFLCSA-N Ouabain Chemical compound O[C@@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@H]1O[C@@H]1C[C@@]2(O)CC[C@H]3[C@@]4(O)CC[C@H](C=5COC(=O)C=5)[C@@]4(C)C[C@@H](O)[C@@H]3[C@@]2(CO)[C@H](O)C1 LPMXVESGRSUGHW-HBYQJFLCSA-N 0.000 description 1
- 206010033557 Palpitations Diseases 0.000 description 1
- 229940116369 Pancreatic lipase Drugs 0.000 description 1
- 102000019280 Pancreatic lipase Human genes 0.000 description 1
- 108050006759 Pancreatic lipase Proteins 0.000 description 1
- 208000007683 Pediatric Obesity Diseases 0.000 description 1
- 240000005158 Phaseolus vulgaris Species 0.000 description 1
- 235000010627 Phaseolus vulgaris Nutrition 0.000 description 1
- 240000007509 Phytolacca dioica Species 0.000 description 1
- 229940023488 Pill Drugs 0.000 description 1
- 241001529246 Platymiscium Species 0.000 description 1
- 241000222341 Polyporaceae Species 0.000 description 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 1
- 241000576755 Sclerotia Species 0.000 description 1
- 229940076279 Serotonin Drugs 0.000 description 1
- 210000003491 Skin Anatomy 0.000 description 1
- 208000001203 Smallpox Diseases 0.000 description 1
- 210000004304 Subcutaneous Tissue Anatomy 0.000 description 1
- 229960000716 TONICS Drugs 0.000 description 1
- 210000001550 Testis Anatomy 0.000 description 1
- JZRWCGZRTZMZEH-UHFFFAOYSA-N Thiamine Natural products CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N JZRWCGZRTZMZEH-UHFFFAOYSA-N 0.000 description 1
- 208000007536 Thrombosis Diseases 0.000 description 1
- LEHOTFFKMJEONL-UHFFFAOYSA-N Trioxopurine Chemical compound N1C(=O)NC(=O)C2=C1NC(=O)N2 LEHOTFFKMJEONL-UHFFFAOYSA-N 0.000 description 1
- 210000004026 Tunica Intima Anatomy 0.000 description 1
- 229940116269 Uric Acid Drugs 0.000 description 1
- 206010046788 Uterine haemorrhage Diseases 0.000 description 1
- 241000870995 Variola Species 0.000 description 1
- 210000003462 Veins Anatomy 0.000 description 1
- 206010052769 Vertigos Diseases 0.000 description 1
- 229940088594 Vitamin Drugs 0.000 description 1
- 229930003451 Vitamin B1 Natural products 0.000 description 1
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Vitamin C Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 1
- BLGXFZZNTVWLAY-CCZXDCJGSA-N Yohimbine Natural products C1=CC=C2C(CCN3C[C@@H]4CC[C@@H](O)[C@H]([C@H]4C[C@H]33)C(=O)OC)=C3NC2=C1 BLGXFZZNTVWLAY-CCZXDCJGSA-N 0.000 description 1
- 235000005042 Zier Kohl Nutrition 0.000 description 1
- 230000003187 abdominal Effects 0.000 description 1
- 230000001154 acute Effects 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive Effects 0.000 description 1
- 230000001919 adrenal Effects 0.000 description 1
- UCTWMZQNUQWSLP-UHFFFAOYSA-N adrenaline Chemical compound CNCC(O)C1=CC=C(O)C(O)=C1 UCTWMZQNUQWSLP-UHFFFAOYSA-N 0.000 description 1
- 235000010081 allicin Nutrition 0.000 description 1
- 229960002734 amfetamine Drugs 0.000 description 1
- 230000000202 analgesic Effects 0.000 description 1
- 238000010171 animal model Methods 0.000 description 1
- 230000001093 anti-cancer Effects 0.000 description 1
- 230000002402 anti-lipaemic Effects 0.000 description 1
- 230000001147 anti-toxic Effects 0.000 description 1
- 235000019789 appetite Nutrition 0.000 description 1
- 230000036528 appetite Effects 0.000 description 1
- 235000010323 ascorbic acid Nutrition 0.000 description 1
- 229960005070 ascorbic acid Drugs 0.000 description 1
- 239000011668 ascorbic acid Substances 0.000 description 1
- 230000003796 beauty Effects 0.000 description 1
- 235000013871 bee wax Nutrition 0.000 description 1
- 239000012166 beeswax Substances 0.000 description 1
- 230000003115 biocidal Effects 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 229940036811 bone meal Drugs 0.000 description 1
- 239000002374 bone meal Substances 0.000 description 1
- 230000004856 capillary permeability Effects 0.000 description 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 1
- 239000002368 cardiac glycoside Substances 0.000 description 1
- 239000000496 cardiotonic agent Substances 0.000 description 1
- 238000006555 catalytic reaction Methods 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 125000001309 chloro group Chemical group Cl* 0.000 description 1
- 230000001684 chronic Effects 0.000 description 1
- 230000037342 citrate cycle Effects 0.000 description 1
- 238000002485 combustion reaction Methods 0.000 description 1
- 239000000287 crude extract Substances 0.000 description 1
- 238000002425 crystallisation Methods 0.000 description 1
- 230000005712 crystallization Effects 0.000 description 1
- 230000002354 daily Effects 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 235000013325 dietary fiber Nutrition 0.000 description 1
- 230000000916 dilatatory Effects 0.000 description 1
- 239000007884 disintegrant Substances 0.000 description 1
- 231100000673 dose–response relationship Toxicity 0.000 description 1
- 238000002651 drug therapy Methods 0.000 description 1
- 230000002124 endocrine Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 235000008384 feverfew Nutrition 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 239000004467 fishmeal Substances 0.000 description 1
- 150000002215 flavonoids Chemical class 0.000 description 1
- 229930003935 flavonoids Natural products 0.000 description 1
- 235000017173 flavonoids Nutrition 0.000 description 1
- 235000013312 flour Nutrition 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 201000003010 gallbladder disease Diseases 0.000 description 1
- JDCPEKQWFDWQLI-LUQKBWBOSA-N ginsenoside Rc Chemical compound C([C@H]1O[C@H]([C@@H]([C@@H](O)[C@@H]1O)O)O[C@@](C)(CCC=C(C)C)[C@@H]1[C@@H]2[C@@]([C@@]3(CC[C@H]4C(C)(C)[C@@H](O[C@H]5[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O5)O[C@H]5[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O5)O)CC[C@]4(C)[C@H]3C[C@H]2O)C)(C)CC1)O[C@@H]1O[C@@H](CO)[C@H](O)[C@H]1O JDCPEKQWFDWQLI-LUQKBWBOSA-N 0.000 description 1
- 150000008131 glucosides Chemical class 0.000 description 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 1
- 235000011187 glycerol Nutrition 0.000 description 1
- 230000034659 glycolysis Effects 0.000 description 1
- 150000002338 glycosides Chemical class 0.000 description 1
- 238000009499 grossing Methods 0.000 description 1
- 239000000122 growth hormone Substances 0.000 description 1
- 231100000869 headache Toxicity 0.000 description 1
- 230000002607 hemopoietic Effects 0.000 description 1
- 230000023597 hemostasis Effects 0.000 description 1
- 235000003642 hunger Nutrition 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 201000001881 impotence Diseases 0.000 description 1
- 230000000977 initiatory Effects 0.000 description 1
- 230000031891 intestinal absorption Effects 0.000 description 1
- 238000009592 kidney function test Methods 0.000 description 1
- 238000002372 labelling Methods 0.000 description 1
- 230000003902 lesions Effects 0.000 description 1
- 235000019626 lipase activity Nutrition 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 235000004213 low-fat Nutrition 0.000 description 1
- 239000000314 lubricant Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 230000037323 metabolic rate Effects 0.000 description 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
- 238000000386 microscopy Methods 0.000 description 1
- 235000019462 natural additive Nutrition 0.000 description 1
- 235000001968 nicotinic acid Nutrition 0.000 description 1
- 229960003512 nicotinic acid Drugs 0.000 description 1
- 239000011664 nicotinic acid Substances 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 239000002417 nutraceutical Substances 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 210000000056 organs Anatomy 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- MYMOFIZGZYHOMD-UHFFFAOYSA-N oxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 235000010987 pectin Nutrition 0.000 description 1
- 229920001277 pectin Polymers 0.000 description 1
- 239000001814 pectin Substances 0.000 description 1
- 230000036581 peripheral resistance Effects 0.000 description 1
- 230000004977 physiological function Effects 0.000 description 1
- 230000035790 physiological processes and functions Effects 0.000 description 1
- 239000006187 pill Substances 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 235000018102 proteins Nutrition 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000001105 regulatory Effects 0.000 description 1
- 230000003014 reinforcing Effects 0.000 description 1
- 230000000717 retained Effects 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 230000036186 satiety Effects 0.000 description 1
- 235000019627 satiety Nutrition 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 230000001624 sedative Effects 0.000 description 1
- 239000000932 sedative agent Substances 0.000 description 1
- 210000000697 sensory organs Anatomy 0.000 description 1
- 210000000813 small intestine Anatomy 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 230000004936 stimulating Effects 0.000 description 1
- 230000002194 synthesizing Effects 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 235000019157 thiamine Nutrition 0.000 description 1
- KYMBYSLLVAOCFI-UHFFFAOYSA-N thiamine Chemical compound CC1=C(CCO)SCN1CC1=CN=C(C)N=C1N KYMBYSLLVAOCFI-UHFFFAOYSA-N 0.000 description 1
- 229960003495 thiamine Drugs 0.000 description 1
- 150000003544 thiamines Chemical class 0.000 description 1
- 239000005495 thyroid hormone Substances 0.000 description 1
- 210000001519 tissues Anatomy 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000001131 transforming Effects 0.000 description 1
- 238000002604 ultrasonography Methods 0.000 description 1
- 230000000304 vasodilatating Effects 0.000 description 1
- 231100000889 vertigo Toxicity 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 235000010374 vitamin B1 Nutrition 0.000 description 1
- 239000011691 vitamin B1 Substances 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- 229930003231 vitamins Natural products 0.000 description 1
- 230000004584 weight gain Effects 0.000 description 1
- 235000015099 wheat brans Nutrition 0.000 description 1
- BLGXFZZNTVWLAY-SCYLSFHTSA-N yohimbine Chemical compound C1=CC=C2C(CCN3C[C@@H]4CC[C@H](O)[C@@H]([C@H]4C[C@H]33)C(=O)OC)=C3NC2=C1 BLGXFZZNTVWLAY-SCYLSFHTSA-N 0.000 description 1
- 229960000317 yohimbine Drugs 0.000 description 1
Abstract
The invention relates to healthy food with weight-losing function as well as the preparation method thereof, which belongs to the healthy food field. The healthy food with weight-losing function comprises active ingredients which are prepared from the following bulk drugs by the weight proportion as follows: gen-seng 1-6, acanthopanax sessiflorus tea 1-8, oolong tea 1-5, notoginseng 1-5, tuckahoe 1-5, and alisma orientale 1-3. Experiments on animals and human bodies show that the inventive healthy food has remarkable weight-losing function and is applicable to people with adiposis caused by various reasons except children.
Description
Technical field
The present invention relates to a kind of health food and preparation method thereof, belong to field of health care food with weight losing function.
Background technology
Obesity is a kind of common chronic disease, and especially in some economically developed countries, the obesity patient increases severely.France's " science and life " periodical reported once that present global obesity patient surpasses 300,000,000, and still is being on the increase, and was the most serious with the America and Europe especially.In developing country, along with the improvement gradually of eating condition, the obesity patient is also increasing gradually.In nearest 10 years world's obesity incidence of disease ranking list statistical graphs that the pharmacology professor GerethWillams of Britain Liverpool An Shu hospital announces, China is listed in the 10th impressively.The nutrition survey report of China shows that also over 20 years, 4 overweight rates of adults in areas group such as Beijing, Shanghai have surpassed 30%.There is very big regional disparity in overweight and obesity rates in China, and the north is higher than south; The developed area surpasses backward areas; The women surpasses the male sex.In addition, children's the simple obesity incidence of disease is also improving constantly, and according to investigations, Beijing child's obesity incidence has had growth at double than the report before 10 years.One studies show that, still suffers from obesity after 40% 7 years old Obese children and 70% puberty, fat teenager grew up.Therefore, children obesity must be treated as early as possible.
Obesity can cause metabolism and endocrine disturbance, and can increase the initiation potential of diseases such as type ii diabetes, atherosclerotic, high fat of blood, hypertension, coronary heart disease.Thereby obesity has become current comparatively general Social Medicine problem.
Up to now, the method for comparatively common prevention and treatment of obesity has four kinds of medicinal treatment, dietetic treatment, kinesiatrics and behavior therapies.Medicine with fat-reducing effect is mainly the appetite inhibitor, quickens the hormone of metabolism, influence is digested and assimilated with the medicine of lipid mobilization etc.Appetite inhibitor is to regulate by the effect of catecholamine and serotonin mediator to ingest and the diet maincenter mostly, reduces appetite, thereby body weight is descended.This class medicine mainly contains amphetamine and derivative Fenfluramine thereof etc.The hormone and the medicine that quicken metabolism mostly rise metabolic rate by increasing living heat, thereby reach the fat-reducing purpose.They mainly contain thyroid hormone, growth hormone and intend beta-adrenergic medicine etc.If the drug main that influence is digested and assimilated increases satiety by prolonging the emptying time of stomach, the factors such as energy and nutraceutical absorption that reduce descend body weight.These medicines comprise dietary fibre, SPE etc.And mobilize fat-splitting medicine is by stimulating beta receptor or suppressing a
2Acceptor impels the fat oxidation heat production to reach the fat-reducing purpose.As norepinephrine, Yohimbine etc.
Though these medicines all have antiobesity action, certain side effect is arranged mostly, cause nausea easily, bad reaction such as abdominal distension, diarrhoea and functional lesion, after drug withdrawal, also be easy to cause bounce-back.And drug therapy the time, generally still needing cooperates low caloric diet to increase fat-reducing effect.In fact, be not only medicinal treatment, even kinesiatrics and behavior therapy also need in conjunction with hyposite.This shows that dietetic treatment is the most basic, safest method of weight-reducing.Therefore the food that screens the pure natural with antiobesity action has become an important topic in the research process of losing weight.People exist a large amount of demands to better effects if, that have no side effect and have the health food of weight losing function.
Summary of the invention
The present invention is directed to the defective in the above-mentioned field, a kind of more efficiently, health food with weight losing function is provided, it is formed all is medicines that can be used for health food production of ratifying through the Ministry of Public Health, state food and Drug Administration, the theory standard that meets integration of drinking and medicinal herbs fully is a kind of green health care food.
Another object of the present invention has provided the preparation method of this health food.
A kind of health food with weight losing function, its active component is mainly made by following bulk drugs: American Ginseng 1-6 part, Sessileflower Acanthopanax Bark tea 1-8 part, oolong tea 1-5 part, pseudo-ginseng 1-5 part, Poria cocos 1-5 part, rhizoma alismatis 1-3 part.
Preferably: 1 part of American Ginseng, 2 parts of Sessileflower Acanthopanax Bark tea, 2 parts in oolong tea, 1 part of pseudo-ginseng, 1 part in Poria cocos, 1 part of rhizoma alismatis.
Also contain garlic 1-3 part, matrimony vine 1-3 part, lotus leaf 1-6 part, hawthorn 1-8 part, chrysanthemum 1-6 part in the wherein said bulk drug.
Preferably: 1 part in garlic, 1 part of matrimony vine, 3 parts on lotus leaf, 2 parts of hawthorn, 1 part of chrysanthemum.
Wherein also contain hydroxycitric acid 0.1-0.5 part, konjaku powder 0.1-0.7 part, l-cn 0.1-0.3 part in the active component.
Preferably: 0.2 part of hydroxycitric acid, 0.3 part of konjaku powder, 0.1 part of l-cn.
The formulation of described health food is a soft capsule.
Its preparation method:
1) take by weighing American Ginseng, pseudo-ginseng 2 flavor bulk drugs in proportion, with 60% alcohol extract twice, it is concentrated as to catch up with not dry extract 1 to merge the extract vacuum;
2) take by weighing Poria cocos, rhizoma alismatis 2 flavor bulk drugs in proportion, with 70% alcohol extract twice, it is concentrated as to catch up with not dry extract 2 to merge the extract vacuum;
3) take by weighing Sessileflower Acanthopanax Bark tea, oolong tea in proportion and extract 1 time with aquae destillata, with the extract vacuum concentrate dry extract 3;
4) take by weighing garlic, matrimony vine, lotus leaf, hawthorn, chrysanthemum in proportion, extract 1 time with aquae destillata, with the extract vacuum concentrate dry extract 4;
5) merge dry extract 1, dry extract 2, dry extract 3 and dry extract 4, it be ground into 200 order powder, take by weighing hydroxycitric acid, konjaku powder, l-cn blending in proportion after, make soft capsule according to a conventional method.
The dry extract that obtains after described the concentrating also need is following dry 3 hours at 50-60 ℃.
Health food with weight losing function disclosed by the invention, it mainly is to be prepared from according to a certain weight ratio by American Ginseng, Sessileflower Acanthopanax Bark tea, oolong tea, matrimony vine, pseudo-ginseng, lotus leaf, Poria cocos, rhizoma alismatis, hawthorn, chrysanthemum, garlic, hydroxycitric acid, konjaku powder, l-cn etc.
Above-mentioned several raw material is made the health food of all kinds of formulations through the active component that ethanol or extraction with aqueous solution obtain.
American Ginseng is the root of Araliaceae American Ginseng Panax quinquefolium L..Also name American ginseng (" property of medicine is examined "), American ginseng (" middle traditional Chinese medicines are planted will ") etc.Found during American Ginseng is wanted 17 kinds of ginsenosides (ginseno)-R0 ,-Rb1 ,-Rb2 ,-Rb3 ,-Rc ,-Rd ,-Re ,-Rf ,-Rg1 ,-Rg2 ,-Rg3 ,-Rh1 ,-Ra0, quinquenosiid R1, gypenoside X1, F3, F11.By proving with experiment in vitro in the body, total saponin(e of stem and leaves of American ginseng and ginsenoside Re, Rb1, Rb can suppress the pancreatic lipase activity, and the anti-obesic action of the total saponin(e of stem and leaves of American ginseng may be because the Ginsenoside Rc, Rb1, Rb in the American ginseng total saponins suppresses the assimilate food result of fat of small intestine.
Sessileflower Acanthopanax Bark tea is the tea that Araliaceae machaka Sessileflower Acanthopanax Bark leaf is made, and Sessileflower Acanthopanax Bark and wilsonii are equal to be belonged to together.Thorn on Sessileflower Acanthopanax Bark stem, the branch seldom is bordering on stinglessly, is distributed in each mountain area on the south the Xiaoxinanlin Mountains, Heilongjiang Province.The Sessileflower Acanthopanax Bark branches and leaves are luxuriant, and flowers and fruits are unusual, except that being a kind of viewing and admiring the tree, still are a kind of wild vegetable and important medicinal plant of keeping healthy.The tea that the Sessileflower Acanthopanax Bark leaf is made contains micro-alkaloid, cardiac stimulant worker glucoside and 0.2% volatile oil and nicotinic acid, contains 0.23% cardiac glycoside, 0.1% volatile oil and a small amount of saponin.The pharmacological action of Sessileflower Acanthopanax Bark tea is multifarious, has strengthening by means of tonics, adjusts effects such as blood pressure, nerve, blood sugar and cholesterol.
Oolong tea is described as " tea of weight reducing " seventies and enters Japan, and spreads in the young woman who pays close attention to fat-reducing very soon, and the research of health efficacy begins to launch.In these more than 30 years,, various effects have been disclosed through numerous researcher's researchs.Include: anti-fat, suppress increased blood pressure, improve medium-sized fat, reduce cholesterol value, suppress that blood sugar rises, anticancer, skin makeup, beauty treatment, improve allergic reaction, various effects such as the rhythm of making the life better, prevention decayed tooth.Fujian Institute of Traditional Chinese Medicine has carried out following experiment: with simple obesity person is the object of observation, drinks continuously after the oolong tea, carries out clinical observation at the effect that suppresses obesity and the regulatory function of phat fat metabolism.Experimental session stops all regimen that has fat-reducing effect and kinesiatrics, requires their normal diet in the time in 6 weeks.Experimental result: simple obesity patient 75 examples, body weight descends, and what remarkable result occurs accounts for 15%, and what effective effect occurs accounts for 52%, and total effective rate reaches 67%.Oolong tea has aliphatic acid effect of combustion in the blood of promotion, the function in the intensive aspect, the consumption that improves heat.
Matrimony vine is the fruit of plant of Solanaceae lycium barbarum Lycium barbarum L..Contain carrotene 3.39% in the matrimony vine, thiamines is mutual 0.23%, and nuclear is yellow mutual 0.33%, Yan acid 1.7%, ascorbic acid 3%.The fruit water-soluble portion contains LBP-X, and about 6%～8%.Studies have shown that the normal mouse of the Acc mRNA content in the injury of hypothalamus obesity mice adipose tissue obviously reduces, and after taking in LBP-X-4, the Acc mRNA level in its adipose tissue significantly improves.Therefore, its functions of lowering blood-fat and reducing weight may be realized by the metabolism of control agent self-energy.
Pseudo-ginseng is the dry root of Araliaceae Panax notoginseng (Burk.) F.H.Chen.Ground such as main product Yunnan mountain of papers, Yanshan County, Guangnan, Maguan and Jingxi, Guangxi, peaceful limit, Baise.Sweet, little hardship, temperature.Gui Jing, stomach warp.The block up that looses stops blooding detumescence ding-tong.Be used for spitting of blood, spit blood, bleeding from five sense organs or subcutaneous tissue is had blood in stool, uterine bleeding, traumatism and bleeding, chest ventral spine pain, tumbling and swelling.Experimental study shows that the Radix Notoginseng powder preparation can stop rabbit intestinal absorption fat.In lipid-metabolism, can reduce TL level and TG content, in feed, sneak into 2% Radix Notoginseng powder, raising rabbit is after 6 weeks, and serum TC and TG content significantly reduce.The histotomy microscopy finds that the fat deposit of Radix Notoginseng powder group arteries significantly alleviates.
Lotus leaf, lotus leaf are the dried leaves of Nymphaeceae platymiscium lotus Nelumbo nucifera Gaertn..Traditional medicine is thought lotus leaf nature and flavor bitter cold, has clearing summer-heat and damply, and hair tonic is sun clearly, and the activity of hemostasis Li Shui of reducing phlegm and internal heat clearing away heart-fire.According to Compendium of Material Medica record " lotus leaf is obeyed it, makes us thin bad ", " hair tonic vigour, benefit helps taste, puckery essence is turbid, the extravasated blood that looses, the detumescence pain is sent out variola ".Auxiliary antilipemic and weight losing function are that block mold is observed the influence of lotus leaf water extract to serum total cholesterol (TC) and triglycerides (TG) with the acute hyperlipemia mouse, and treated in vitro is observed medicine has inhibition trend to the liver cell synthetic cholesterol.With the lotus leaf alcohol extract hyperlipemia in mice is carried out pharmacological evaluation, the result proves that the lotus leaf alcohol extract can obviously reduce mouse TC content, with positive controls (yodonicit sheet) there was no significant difference.With the lotus leaf biology total alkali is index, investigates the influence of such material to fat hyperlipidemia rats blood fat and body weight.The result shows, lotus leaf biology total alkali 2.14～10.7mg/kg all can reduce TC, TG and the body weight gain index such as the Lee ' s index of obese rat, relatively there were significant differences (P＜0.05 or P＜0.01) and have dose dependent with model group, but not obvious to HDL (HDL-C) effect.Experimental results show that the lotus leaf electuary can reduce TC, the TG content in the tentative hyperlipidemia of rabbit, all has inhibitory action to lipid precipitation in the animal tissue and atherosclerotic.By intervention test to the high fat of blood animal model, confirm that lotus leaf can slow down the increase of obese rat body weight, promote the adipocyte metabolism, reduce adipocyte synthetic glycerine three esters and suck aliphatic acid, enzyme hydrolysis and the free fatty of strengthening triglycerides discharge in blood, and certain functions of lowering blood-fat and reducing weight is arranged.
Poria cocos is the dry sclerotia of Polyporaceae plant Poria cocos Poria cocos (Schw.) Wolf.It is sweet, light to distinguish the flavor of, and property is flat.The thoughts of returning home, spleen, lung channel.Function: eliminating dampness and diuresis, beneficial spleen and stomach, antitoxic heart-soothing and sedative.Cure mainly: difficult urination, oedema turgor, phlegm and retained fluid are coughed contrary, n and V, are had loose bowels, seminal emission, stranguria with turbid discharge, palpitation with fear, forgetful.
Rhizoma alismatis is the stem tuber of Alismataceae plant rhizoma alismatis Alisma orientale (Sam.) Juzep..Cold in nature, it is sweet to distinguish the flavor of.Diuresis, heat-clearing.Be used for difficult urination, oedema turgor, the oliguria of having loose bowels, phlegmatic vertigo, the puckery pain of heat pouring, hyperlipemia.Rhizoma alismatis can obviously reduce cholesterol in serum, triglycerides and LDL-C, promotes the Serum HDL-C level to raise, the generation of obviously resisting the aortic tunica intima patch, and administration in advance then shows prevention effect.
Hawthorn is the fruit of rosaceous plant hawthorn Crataegus pinnatifida Bge. or fructus crataegi cuneatae.Also haw (" 101 choosing side ") in the famous mountain.Flavor acid, sweet, slightly warm in nature.Return spleen, stomach, Liver Channel.Function: long-pending, diffusing extravasated blood, expelling tenia help digestion.
Chrysanthemum, this product are the dry capitulum of feverfew.Contain chrysanthemum glycosides, chloro acid, flavonoids and mcg vitamin B1 in spending.Pharmacological action, this product coronary artery dilating increases coronary flow, brings high blood pressure down, and resists local capillary permeability.Analgesic in addition, antibacterial in addition etc.Modern times are useful on treatment hypertension, artery sclerosis, coronary heart disease etc.
Garlic is in China, Greece, Rome, the Egyptian all useful garlic history as health food.The bactericidal action of garlic is well-known, and the allicin in the garlic has the antibiotic effect.Therefore trithio pi-allyl in the garlic has vasodilative effect, can resist hematoblastic cohesion, can reduce peripheral resistance and brings high blood pressure down and prevent thrombosis.Garlic also has norcholesterol, aid digestion and resist effect such as tumour.Respectively with the dosage of 0.4g (kg body weight d) and 1.2g (kg body weight d) the fat rat model 30d that feeds, two dosage groups are compared with model control group with garlic runic thing, and body weight, physique heavily reach body fat and descends than conspicuousness is all arranged, and existence and dosage correlation.The antiobesity action of garlic may be because the sulfide compound that the multiple pi-allyl in the crude extract, propyl group and methyl are formed.These sulfide compounds are by increasing BAT and promoting adrenal medella secretion adrenaline, norepinephrine to improve the body heat production.
Hydroxycitric acid, the HCA full name is: hydroxycitric acid; Chinese name is " hydroxycitric acid ".It is the natural extract of a kind of " HCA " by name.The action principle of HCA exactly when human glucose transfers fat to, suppresses the ferment of one of them ATP Citrate lyase, and aliphatic acid can't be synthesized, and suppresses the carrying out that sugar is separated (glycolysis) effect.HCA chemical constitution: HO-CH
2-(CH
2)
6-CH=CH-COOH (C
10H
18O
3).In food entered our body, carbohydrate promptly was decomposed into little molecule glucose, and entering blood becomes blood sugar, and then to deliver to each cell of whole body be energy with the metabolism.If glucose is not utilized immediately, just be stored in muscle and form glycogen (Glycogen), if but that glycogen has stored is full, glucose promptly is converted to citric acid through the sugar effect of separating with citrate cycle, synthesizes fat through ferment ATP-Citrate lyase catalysis again.The contained HCA of HCA extract is the citric acid analog, can compete the activity that suppresses ferment ATP-Citrate lyase, so unnecessary carbohydrate is converted to fatty process in the baffle, finds after deliberation, in 8-12 hour after meal, the aliphatic acid that HCA can reduce 40-70% synthesizes.HCA comes from the pure natural extract, clear and definite chemical composition of Western medicine raw material and fat-reducing mechanism are arranged again simultaneously, it is by suppressing the synthetic of fat, promote the burning of aliphatic acid, reduce the absorption of food, the Trinity reaches the effect of weight reducing fat-reducing, be a kind of rare, present desirable, the most healthy Weight-reducing health raw material of fat-reducing effect.HCA prevents that body weight from increasing (bounce-back) better effects if to helping behind the weight-reducing.Not at all easy body weight is subtracted the people that gets off for those, added the product of HCA raw material, body weight that can more effective maintenance oneself by picked-up.HCA is particularly suitable for the Asians: it should be noted that especially because citrate lyase (citrate lyase) only works under the situation that carbohydrate is excessively taken in, so to be particularly suitable for starch be the Asians of staple food.In other words Chinese to use HCA to be used for the weight-reducing effect better than the occidentals.HCA is a kind of natural extract, does not still have report at present and shows its toxic or side effect.
Its main component of konjaku powder is mannosan, protein, pectin and starch.It is a kind of high fiber, low fat, natural diet food low in calories.Contain the mannosan about 60% in the konjaku, water imbibition is very strong, and suction back volumetric expansion can be filled stomach and intestine, eliminates hunger.Konjaku can delay digesting and assimilating of nutrient, reduces the absorption to monose, makes aliphatic acid synthetic decline in vivo, thus the growth of control body weight, so can reach the purpose of fat-reducing.
L-cn (L-carnitine) is once called as DL-carnitine chloride, is to be found first in meat extract by Russianize scholar Gulewitsch and Krimberg in 1905.The molecular formula C of L-carnitine
7H
15NO
3, relative molecular mass 161.20.It is a kind of white water imbibition crystallization, and very easily water-soluble (250g/100g) and ethanol are insoluble to ether, acetone, benzene, 210～212 ℃ of fusing points.Because the L-carnitine can satisfy physiological requirements by synthesizing by people and multiple animal in health, so the vitamin that it neither be truly, be the vitamin-like material of a kind of class.It has a lot of important physiological function.
Modern Chinese medicine is thought, obesity cause of disease complexity, and each disease type haves both at the same time clinically, treatment and the suitable giving consideration to both the incidental and fundamental of health care, the same usefulness of reinforcing and reducing methods, the number method is also executed, and can obtain reasonable effect.
Modern Chinese medicine thinks that the disease somatotype of distinguishing of obesity can be divided into five kinds: 1. insufficiency of the spleen damp-obstruction type clinical manifestation be body obesity, limbs be stranded weight, lassitude hypodynamia, abdominal fullness and distention, receive the difference food less, big loose stool is thin, tongue nature is light, greasy and thin fur, arteries and veins is slow or moisten carefully.Much more this kind of see clinically.The health care principle is invigorating the spleen for eliminating dampness.2. the spleen kidney both deficiency type clinical manifestation be body obesity, impractical swelling, fatigue and weak, deficiency of QI with disinclination to talk, movingly pant, dizzy chilly, that food is received less is poor, waist knee crymodynia, big loose stool is thin or have loose bowels just before dawn, impotence, tongue nature is light, tongue is thin in vain, deep thready pulse.Severe obesity patient mostly is this kind of.The health care principle is warm yang transforming qi Li Shui.3. the clinical manifestation of stomach energy damp-obstruction type be the body obesity, like that food delicious food or rapid digestion of food and polyorexia, halitosis dry, constipation, tongue nature are red, yellowish fur, slippery and rapid pulse.This kind of mostly is the strong young and middle-aged overweight people of body.The health care principle is the logical internal organs of clearing away heat and eliminating dampeness.4. the qi stagnation and blood stasis type clinical manifestation be that body obesity, two side of body turgors, gastral cavilty ruffians are full, irritated irritability, mouth parched and tongue scorched, have a dizzy spell, insomnia and dreamful sleep, irregular menstruation or amenorrhoea, dark tongue quality have ecchymosis, wiry and frequent pulse or thin string.Obesity with the passing of time the person visible this kind of.The health care principle is a liver-smoothing, qi-regulating, promoting blood circulation and removing blood stasis.5. the clinical manifestation of kidney-yin deficiency type is body obesity, dizzy headache, dysphoria in chestpalms-soles, soreness and weakness of waist and knees, the red few tongue of tongue, thready rapid pulse or thin string.This kind of is relatively more rare clinically.The health care principle is enriching yin and nourishing kidney.
We are monarch drug in a prescription with American Ginseng, Sessileflower Acanthopanax Bark tea, oolong tea, matrimony vine, pseudo-ginseng, benefit lung yin, the clear fire of deficiency type, replenish qi to invigorate the spleen, tonify the kidney to relieve mental strain, nourishing liver and kidney, benefiting shrewd head, anti-simultaneously obesity, prevention fat absorption, reduction TL level and TG content reach effect of weight reducing; With lotus leaf, Poria cocos, rhizoma alismatis, hawthorn, chrysanthemum, garlic is ministerial drug, and beneficial spleen and stomach, eliminating dampness and diuresis, long-pending, the extravasated blood that looses that helps digestion are aid digestion simultaneously, bring high blood pressure down; Help again with hydroxycitric acid, konjaku powder, l-cn, the raw material that adds this three flavors natural additive for foodstuff makes material as the assistant of this prescription, can play minimizing and delay digesting and assimilating of nutrient, reduction is to the absorption of monose, make aliphatic acid synthetic decline in vivo, thereby the growth of control body weight, thus can reach the purpose of fat-reducing, also make simultaneously this prescription fat-reducing effect better more comprehensively.
The used medicine of the present invention all adopts the ethanol or the aqueous solution to extract, the temperature that refluxes is lower than 100 ℃, make active ingredient in the medicine be difficult for Yin Gaowen and change, when concentrated, adopt vacuum to concentrate simultaneously, make the active ingredient in the extract not be subjected to temperatures involved, avoided some destruction and loss, preserved the nutritional labeling and the fragrance of raw material better heat-labile active ingredient.The dry extract that obtains after concentrating need 50-60 ℃ dry 3 hours down, could finish-drying.
Experiment shows that health products of the present invention have tangible weight losing function through animal and human's body, can also strengthen immunity simultaneously, need to be used to slimmer and immunocompromised person, also is applicable to children.
The prepared dry extract active component of the present invention can add various conventional auxiliary material required when preparing different dosage form, as disintegrant, lubricant, adhesive etc., method of Chinese medicinal with routine is prepared into any peroral dosage form commonly used, as pill, powder, tablet, capsule, oral liquid etc., the present invention adopts soft capsule dosage form, dry extract and edible corn ready-mixed oil are mixed at 1: 1.2, and add the beeswax of dry extract weight 2%, the soft capsule of packing into.Each soft capsule contains active component 0.72g.The rhythm of life of considering the modern is than very fast, and the present invention adopts soft capsule preparation, and is easy to carry, absorb rapidly.
The specific embodiment
Further set forth health food of the present invention with experimental example by the following examples.
Embodiment 1
Feed proportioning: American Ginseng 1000g, Sessileflower Acanthopanax Bark tea 2000g, oolong tea 2000g, garlic 1000g, matrimony vine 1000g, pseudo-ginseng 1000g, lotus leaf 3000g, Poria cocos 1000g, rhizoma alismatis 1000g, hawthorn 2000g, chrysanthemum 1000g, hydroxycitric acid 200g, konjaku powder 300g, l-cn 100g.
Its preparation method:
1) take by weighing American Ginseng, pseudo-ginseng 2 flavor bulk drugs in proportion, extract and use 60% alcohol extract, refluxed 3 hours, extract twice, merging extract vacuum is concentrated as to catch up with not dry extract 1;
2) take by weighing Poria cocos, rhizoma alismatis 2 flavor bulk drugs in proportion, extract and use 70% alcohol extract, refluxed 3 hours, extract twice, merging extract vacuum is concentrated as to catch up with not dry extract 2;
3) take by weighing Sessileflower Acanthopanax Bark tea in proportion, oolong tea extracts with distilled water, refluxed 2 hours, with the extract vacuum concentrate dry extract 3;
4) take by weighing garlic, matrimony vine, lotus leaf, hawthorn, chrysanthemum in proportion, extract, refluxed 2 hours with distilled water, with the extract vacuum concentrated dry extract 4;
5) merge dry extract 1, dry extract 2, dry extract 3 and dry extract 4, it is ground into 200 order powder, take by weighing hydroxycitric acid, konjaku powder, l-cn more in proportion, after the 1700g blending, be filled into capsule shells altogether by the soft capsule method for production.It is 0.72g that every soft capsule contains active component.
Embodiment 2
Feed proportioning: American Ginseng 2000g, Sessileflower Acanthopanax Bark tea 8000g, oolong tea 1000g, garlic 3000g, matrimony vine 2000g, pseudo-ginseng 2000g, lotus leaf 1000g, Poria cocos 5000g, rhizoma alismatis 2000g, hawthorn 1000g, chrysanthemum 6000g, hydroxycitric acid 100g, konjaku powder 700g, l-cn 200g.
Its preparation method such as embodiment 1.
Embodiment 3
Feed proportioning: American Ginseng 6000g, Sessileflower Acanthopanax Bark tea 1000g, oolong tea 5000g, garlic 2000g, matrimony vine 3000g, pseudo-ginseng 5000g, lotus leaf 6000g, Poria cocos 2000g, rhizoma alismatis 3000g, hawthorn 8000g, chrysanthemum 3000g.
Step 1,2,3,4 among its preparation method such as the embodiment 1, the 5th step was:
5) merge dry extract 1, dry extract 2, dry extract 3 and dry extract 4, drying is 3 hours under 50-60 ℃, and it is ground into 200 order powder, is active component of the present invention, is filled into capsule shells by the soft capsule method for production, the De Benming health food.
Embodiment 4
Feed proportioning: American Ginseng 4000g, Sessileflower Acanthopanax Bark tea 3000g, oolong tea 4000g, pseudo-ginseng 4000g, Poria cocos 2500g, rhizoma alismatis 2000g.
Step 1,2 among its preparation method such as the embodiment 1,3, the four steps are:
4) merge dry extract 1, dry extract 2, dry extract 3, drying is 3 hours under 50-60 ℃, and it is ground into 200 order powder, is active component of the present invention, is filled into capsule shells by the soft capsule method for production, the De Benming health food.
It all is medicines that can be used for health food production of ratifying through the Ministry of Public Health, state food and Drug Administration that the formula material of this health food is formed, and meets the theory standard of integration of drinking and medicinal herbs fully, is a kind of " green " health food.
According to " health food check and assessment technique standard " (2003 editions) criterion, show that through zoopery and human experimentation health food of the present invention has tangible weight losing function to the weight losing function health food.
Health food weight losing function of the present invention zoopery and human experimentation the results are shown in experimental example 1 and experimental example 2.
The animal experiment study of 1 health food weight losing function of experimental example is as follows.
1.1 principle
This method is to bring out the animal obesity with high heat food, is tried thing (fat model) again, observes the variation of the weight of animals, body fat content and body health is had harmless.
1.2 instrument
Animal balance, disscting instrument etc.
1.3 test method
1.3.1 animal used as test selects for use body weight to be the adult rat of 180g ± 200g, and is male, 100, available from Animal Experimental Study center, Hubei Province, the quality certification number is the moving word of doctor 2007-0806 number.Every group 10.
1.3.2 dosage grouping is tried thing (health food of present embodiment 1, down with) with adult's recommended amounts oral 720mg/d every day, by adult 60kg batheroom scale, promptly 5 times of 12mg/ (kg body weight) is wherein low dose group, and 10 times is high dose group.Control group adopts blank.Tried thing and given time totally 4 all 30d.
1.3.3 nutrient fodder prescription
Basal feed: pearling cone meal 20%, dehydrated vegetable (removing the cabbage of moisture) 10%, bean powder 20%, yeast 1%, bone meal 5%, corn flour 16%, wheat bran 16%, fish meal 10%, salt 2%.
Nutrient fodder: basal feed 80%, lard 10%, yolk powder 10%.
1.3.4 the fat modelling of experimental procedure: behind nutrient fodder hello rat 30d, the rat of the same age that weight gain is fed than normal diet increases, and difference has conspicuousness, and then the fat model of Jian Liing meets requirement of experiment.After the fat model of rat is set up, be divided into model control group and high and low two at random and tried the thing test group.Test group gives the thing that tried of various dose, and model control group gives coordinative solvent.
1.3.5 observation index body weight, food ration, food utilization, body fat quality (testis and perirenal fat pad).
Table 1 is respectively organized rat growth indexes and Lipid Metabolism Determination value
* P＜0.05 of comparing with control group; * and control group be (P＜0.01) relatively
A is n=6.
1.3.6 the result is as shown in table 1, high and low dose health products group and control group compare, and the fat weight average obviously reduces around body weight, the genitals, but indifference between the high and low dose group.Under high-power microscope, adipocyte number seen in each visual field, the health products group obviously more than control group, but cell volume is significantly less than control group, illustrate that fatty amount is few in the adipocyte of health products group, cell accumulation together, the cell number of seeing in the therefore same visual field is more.Above result shows, these health products really can reduce fatty accumulation, and in a single day reach effective dose again escalated dose can not make fat-reducing effect better.
1.4 data are handled and the result judges
The body weight of experimental group and body fat quality, or body weight and fat body ratio be lower than model control group, and difference has conspicuousness, and food ration significantly is not lower than model control group, and body is not had obvious damage, and promptly this result of the test of being tried thing animal weight losing function of decidable is positive.
According to " health food check and assessment technique standard " (2003 editions) criterion to the weight losing function health food, this health food of decidable has antiobesity action.
Experimental example 2
The human experiment experimental study of this health food fat-reducing effect is as follows.
2.1 principle
Give the simple obesity experimenter the edible thing (health food of present embodiment 2, down together) that tried, observe body weight, body fat content and body health is had harmless.
2.2 instrument human body component sensing equipment, batheroom scale.
2.3 test method
2.3.1 experimenter's selection study subject is the simple obesity crowd.Become the interior total fatty percentage of human body to reach man＞25%, the volunteer of woman＞30%.Children and teenager survey body weight 20% of the body weight that is above standard.The experimenter does not have gallbladder disease.
2.3.2 the experimenter that should not participate in the experiment that we confirm merge have the inclination, serious diseases such as liver, kidney and hemopoietic system, the mental patient; Credit is not tried thing in accordance with regulations, can't judge effect or data not umbra sound effect or security judgement person; Take the article relevant in a short time, have influence on result's judgement person with being tried function.
2.3.3 test requirements document
This health food is the weight losing function health food that does not substitute staple food.Control experiment design between own control and group is adopted in the weight losing function test that does not substitute staple food in accordance with regulations.Body weight, body lipid amount by the experimenter are divided into test-meal group and control group at random, consider influence result's principal element such as age, sex, diet, moving situation etc. as far as possible, carry out harmony to check, with the comparativity between the assurance group.Every group of experimenter of test number is no less than 10 examples.
2.3.4 tried the dosage and the using method of thing
This health food is not for substituting the weight losing function health food of staple food: the test-meal group is taken by instructions of taking, the dose recommended and is tried thing, tried thing with adult's recommended amounts oral 720mg/d every day, by adult 60kg batheroom scale, be that 12mg/ (kg body weight) takes, 2 times is low dose group wherein, and 3 times is high dose group.Control group adopts blank.Carry out the test-meal experiment by blind method.Tried thing and given time 30d.
2.3.5 observation index
2.3.5.1 safety indexes
General situation comprises spirit, sleep, diet, stool and urine, blood pressure etc., blood, urine, just routine inspection, liver, kidney function test Chest X-rays, electrocardiogram, Abdominal B type ultrasonography inspection (every index is checked once before experiment), blood uric acid, urine ketoboidies.The exercise tolerance test: the exercise tolerance method of testing is the cycle ergometer test.The experimenter is with identical motion scheme power cycle test before and after the test-meal, recorded heart rate, and use each experimenter's of nomography indirect determination of Sstrand and Ryhming maximal oxygen uptake (L/ branch).Other bad reactions are observed: as apocleisis, diarrhoea etc.
2.3.5.2 dietary factors and motion conditions requirement
The experimenter is carried out the 3d dietary survey before experiment beginning, before the end.In order to get rid of the influence of dietary factor, require consistent with diet as far as possible to result of the test.Observation is inquired in motion to the experimental session experimenter, requires consistent with the daily exercise situation.
2.3.5.3 effect index
Body weight, calculating body mass index, SBW, body fat Determination on content etc. see Table 2 before and after the experiment:
Table 2 is respectively organized human body indicators and Lipid Metabolism Determination value (every group of experimenter of test number 10 examples)
* P＜0.05 of comparing with control group; * and control group be (P＜0.01) relatively
1.3.6 the result is as shown in table 2, high and low dose health products group and control group compare, and body weight all obviously reduces, but indifference between the high and low dose group.Under high-power microscope, adipocyte number seen in each visual field, the health food group obviously more than control group, but cell volume is significantly less than control group, illustrate that fatty amount is few in the adipocyte of health food group, cell accumulation together, the cell number of seeing in the therefore same visual field is more.Above result shows that this health food really can reduce the accumulation of fat.Carry out overall merit according to These parameters measurement result before and after the test, wherein body fat content is learned processing difference by statistics conspicuousness, and body health is not had obvious damage.
According to " health food check and assessment technique standard " (2003 editions) criterion to the weight losing function health food, this health food of decidable has antiobesity action.
Claims (9)
1. health food with weight losing function, its active component is mainly made by following bulk drugs: American Ginseng 1-6 part, Sessileflower Acanthopanax Bark tea 1-8 part, oolong tea 1-5 part, pseudo-ginseng 1-5 part, Poria cocos 1-5 part, rhizoma alismatis 1-3 part.
2. health food according to claim 1, wherein the weight portion of bulk drug is: 1 part of American Ginseng, 2 parts of Sessileflower Acanthopanax Bark tea, 2 parts in oolong tea, 1 part of pseudo-ginseng, 1 part in Poria cocos, 1 part of rhizoma alismatis.
3. health food according to claim 1 also contains garlic 1-3 part, matrimony vine 1-3 part, lotus leaf 1-6 part, hawthorn 1-8 part, chrysanthemum 1-6 part in the described bulk drug.
4. health food according to claim 3, wherein the weight portion of bulk drug is 1 part in garlic, 1 part of matrimony vine, 3 parts on lotus leaf, 2 parts of hawthorn, 1 part of chrysanthemum.
5. health food according to claim 3 wherein also contains hydroxycitric acid, konjaku powder and l-cn in the active component, its weight portion is hydroxycitric acid 0.1-0.5 part, konjaku powder 0.1-0.7 part, l-cn 0.1-0.3 part.
6. health food according to claim 5,0.2 part of described hydroxycitric acid, 0.3 part of konjaku powder, 0.1 part of l-cn.
7. health food according to claim 6, the formulation of described health food are soft capsule.
8. the preparation method of the described health food of claim 7 comprises the steps:
1) take by weighing American Ginseng, pseudo-ginseng 2 flavor bulk drugs in proportion, with 60% alcohol extract twice, merge the extract vacuum concentrated dry extract 1;
2) take by weighing Poria cocos, rhizoma alismatis 2 flavor bulk drugs in proportion, with 70% alcohol extract twice, merge the extract vacuum concentrated dry extract 2;
3) take by weighing Sessileflower Acanthopanax Bark tea, oolong tea in proportion and extract 1 time with distilled water, with the extract vacuum concentrate dry extract 3;
4) take by weighing garlic, matrimony vine, lotus leaf, hawthorn, chrysanthemum in proportion, extract 1 time with distilled water, with the extract vacuum concentrate dry extract 4;
5) merge dry extract 1, dry extract 2, dry extract 3 and dry extract 4, it be ground into 200 order powder, take by weighing hydroxycitric acid, konjaku powder, l-cn blending in proportion after, make soft capsule according to a conventional method.
9. preparation method according to claim 8, the dry extract that obtains after described the concentrating also need is following dry 3 hours at 50-60 ℃.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008101035074A CN101253903B (en) | 2008-04-07 | 2008-04-07 | Health food with fat-reducing function and its preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008101035074A CN101253903B (en) | 2008-04-07 | 2008-04-07 | Health food with fat-reducing function and its preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101253903A CN101253903A (en) | 2008-09-03 |
| CN101253903B true CN101253903B (en) | 2010-09-15 |
Family
ID=39889293
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2008101035074A Expired - Fee Related CN101253903B (en) | 2008-04-07 | 2008-04-07 | Health food with fat-reducing function and its preparation |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101253903B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106723085A (en) * | 2016-07-15 | 2017-05-31 | 甘肃青黛百年健康管理股份有限公司 | It is a kind of by Yin Yang balancing adjusting the health preparation of body fat |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102106550A (en) * | 2011-02-18 | 2011-06-29 | 西南大学 | Weight losing food |
| CN102422937B (en) * | 2011-10-13 | 2013-04-24 | 陇东学院 | Preparation method of acanthopanax brachypus harms color-changing health care tea |
| CN102669342A (en) * | 2012-05-20 | 2012-09-19 | 北京绿源求证科技发展有限责任公司 | Dietetic health-care weight-reducing tea electuary |
| CN104770513A (en) * | 2014-01-11 | 2015-07-15 | 山东大学（威海） | Western red ginseng-amorphophallus konjac tea preparation method |
| CN104489162A (en) * | 2014-12-11 | 2015-04-08 | 张志科 | Composition, tea paste and application of composition |
| CN106309551A (en) * | 2015-07-03 | 2017-01-11 | 华北制药秦皇岛有限公司 | Perilla seed compound preparation and preparation method thereof |
| CN105146656A (en) * | 2015-09-07 | 2015-12-16 | 王保红 | Drink composition containing L-carnitine and plant extracts as well as preparation method and application of drink composition |
| CN111419929A (en) * | 2020-05-07 | 2020-07-17 | 刘庆国 | Preparation method of traditional Chinese medicine weight-losing oral liquid |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1215561A (en) * | 1997-10-27 | 1999-05-05 | 邢文海 | Health tea |
| CN1269985A (en) * | 2000-03-27 | 2000-10-18 | 陈中杰 | Health-care food for preventing electronic pollution |
| CN1586331A (en) * | 2004-06-30 | 2005-03-02 | 张东亮 | Multifunctional fat reducing nutrition regimen drink |
| CN1613338A (en) * | 2004-07-24 | 2005-05-11 | 王�华 | Compound weight reducing tea |
| CN101073349A (en) * | 2007-06-28 | 2007-11-21 | 刘统新 | Tea with body-strengthening and lung-invigorating functions |
-
2008
- 2008-04-07 CN CN2008101035074A patent/CN101253903B/en not_active Expired - Fee Related
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1215561A (en) * | 1997-10-27 | 1999-05-05 | 邢文海 | Health tea |
| CN1269985A (en) * | 2000-03-27 | 2000-10-18 | 陈中杰 | Health-care food for preventing electronic pollution |
| CN1586331A (en) * | 2004-06-30 | 2005-03-02 | 张东亮 | Multifunctional fat reducing nutrition regimen drink |
| CN1613338A (en) * | 2004-07-24 | 2005-05-11 | 王�华 | Compound weight reducing tea |
| CN101073349A (en) * | 2007-06-28 | 2007-11-21 | 刘统新 | Tea with body-strengthening and lung-invigorating functions |
Non-Patent Citations (1)
| Title |
|---|
| 姚凤云.降脂减肥胶囊的药学及药理学研究.《黑龙江中医药大学》.2007,1-77. * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106723085A (en) * | 2016-07-15 | 2017-05-31 | 甘肃青黛百年健康管理股份有限公司 | It is a kind of by Yin Yang balancing adjusting the health preparation of body fat |
Also Published As
| Publication number | Publication date |
|---|---|
| CN101253903A (en) | 2008-09-03 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101253903B (en) | Health food with fat-reducing function and its preparation | |
| CN101695376B (en) | Health-care food for preventing diabetes | |
| CN101579120A (en) | Nutritional food with weight-losing function and preparation method thereof | |
| CN104322617B (en) | Biscuit of a kind of auxiliary hyperglycemic and preparation method thereof | |
| CN104435775A (en) | Chinese medicinal health-care spirit and preparation method thereof | |
| CN102172269B (en) | Hidegelatin fabricated food with beautification function | |
| CN102784295B (en) | Health-care preparation formula for improving female climacteric syndrome and preparation method of same | |
| CN101518336A (en) | Nutrition food with oxidation resistance function and preparation method thereof | |
| CN107518259A (en) | A kind of food and preparation method thereof | |
| CN102526478B (en) | Formula of health-care medicine with functions of strengthening immunity and reducing blood sugar | |
| CN107772340A (en) | A kind of kidney tonifying nourishing and strengthening vital black dietary fiber meal replacing food | |
| CN108524814A (en) | A kind of Chinese medicine composition and preparation method thereof for reducing blood glucose | |
| KR100947278B1 (en) | A carbohydrate and lipid absorption inhibitory nelumbo composition and its manufacturing process thereof | |
| CN101455379A (en) | Nutrient food suitable of diabetic and preparation method thereof | |
| CN107048386A (en) | A kind of sexual function adjusts health food | |
| CN103689559A (en) | Health-preserving health food formula beneficial for improving gastrointestinal functions and preparation method thereof | |
| CN106937741A (en) | A kind of degreasing linseed meal cancer-resisting health slimming method and preparation method thereof | |
| CN102551046A (en) | Natural health composition for weight reduction and application of same | |
| CN106418501A (en) | Healthcare food with weight reducing function | |
| CN101243883B (en) | Health food with function of reducing blood sugar and its preparation | |
| CN101491338A (en) | Nutrient food capable of improving sleep and preparation method thereof | |
| CN106173871A (en) | A kind of fall three-hypers dumplings and preparation method thereof | |
| CN103181557A (en) | Nutritious food with slimming function and preparation method thereof | |
| CN105124078A (en) | Gardenia blood-glucose-reducing and lipid-reducing healthcare tea and preparing method thereof | |
| CN104825821A (en) | Medicine for treating diabetes and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20100915 Termination date: 20140407 |