CN102423437A - Double-prescription medicament for treating apoplectic hemiplegia and preparation method thereof - Google Patents
Double-prescription medicament for treating apoplectic hemiplegia and preparation method thereof Download PDFInfo
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- CN102423437A CN102423437A CN2011104418484A CN201110441848A CN102423437A CN 102423437 A CN102423437 A CN 102423437A CN 2011104418484 A CN2011104418484 A CN 2011104418484A CN 201110441848 A CN201110441848 A CN 201110441848A CN 102423437 A CN102423437 A CN 102423437A
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Abstract
The invention discloses a double-prescription medicament for treating apoplectic hemiplegia and a preparation method thereof. The medicament disclosed by the invention is prepared by combination of a prescription A and a prescription B, wherein the prescription A comprises eupolyphage sinensis, scorpion, gecko, centipede, morinda flesh, broomrape, stir-fried fankincense, leeches, prepared aconite root and the like, and the prescription B comprises raw hawthorn extract, costus root extract, astragalus root extract, clematis root extract, red date extract, achyranthes root extract, yam extract and the like. The invention also provides a preparation method of the medicament. The medicament disclosed by the invention has the advantages of improving cerebral apoplexy treatment and prevention level, reducing cerebral apoplexy incidence, disability rate and mortality, having high overall effective rate and the like.
Description
Technical field
What the present invention relates to is a kind of Chinese medicine composition of treating apoplectic hemiplegia, specifically is meant a kind of two prescription medicines that use Chinese herbal medicine as raw material treatment apoplectic hemiplegia, the invention still further relates to the method for preparing of this medicine.
Background technology
It is the disease of main clinical manifestation with brain ischemia and hemorrhagic damage symptom that apoplexy is one group, claims apoplexy or cerebrovascular accident again, has high case fatality rate and disability rate.Apoplexy is turned from side to side original full of life and energy people become maimed, many patient's hemiplegia, and numb hand and foot, the dimness of vision, the entanglement even mute of speaking, dysphagia, hypomnesis can not be understood others' speech, disposition change etc.Even diagnosis and treatment are timely, also sequela that leave more, with the passing of time delay is difficult for recovering, careful as not, and the recurrence possibility is arranged again, brings a lot of inconvenience to patient and family.
The traditional Chinese medical science is thought, the many hyperactivity of YANG due to deficiency of YIN of cerebral hemorrhage, fall ill in hypertension tired or excited in, the many deficiency of vital energys of cerebral thrombosis, frequently-occurring disease are when peace and quiet, it is many particularly to send out the patient in the sleep, particularly to cause the blood vessels stasis of blood to stagnate a little less than the deficiency of YANG QI relevant with the deficiency of vital energy.The stagnation of phlegm gods, mainly still start in QI and blood contrary disorderly after, body fluid can not fortune, it is not normal to dredge cloth, body fluid turns to phlegm-damp.So the apoplexy that yang deficiency causes, shared ratio is also many.Especially in the rural area, because the comparison of controlling of blood pressure is weak, the ratio of excessive rising of liver-YANG is more than the city, and the ratio of cerebral hemorrhage also is higher than cerebral infarction, thereby the shared ratio of the apoplexy that yang deficiency causes is also more.
Apoplexy is the common refractory disease of serious harm human health and life security, and motherland's medical science is classified it as first of " wind, consumptive disease, distension, diaphragm " four big difficult disease, exists obvious three-hypers, the phenomenon that promptly sickness rate is high, disability rate is high, mortality rate is high.And must cross the patient of apoplexy, and also being prone to recurrence again, every recurrence once increases the weight of once.
Summary of the invention
The purpose of this invention is to provide the treatment and the prevention level that can improve apoplexy, sickness rate, disability rate and mortality rate a kind of who reduces apoplexy is used to two prescription medicines of treating apoplectic hemiplegia and preparation method thereof.
Realize that technical scheme of the present invention is following: a kind of two prescription medicines that are used to treat apoplectic hemiplegia, said medicine is made up of the prescription A of 5～10 weight portions and the prescription B of 3～9 weight portions,
Said prescription A is by the Eupolyphaga Seu Steleophaga extract; Scorpio extract; The Gekko Swinhonis extract; Scolopendra extract; The Radix Morindae Officinalis extract; Herba Cistanches extract; Olibanum extract; Hirudo extract; Radix Aconiti Lateralis Preparata extract; Stir-baked SQUAMA MANITIS; Styrax; Benzoinum; Borneolum Syntheticum; Moschus; Realgar; Venenum Bufonis; The artificial Calculus Bovis; Margarita powder; Piece of antler; Fructus Mume; Ganoderma spore powder; Semen Strychni (processed) powder; Oligochitosan; Semen Vitis viniferae extract; Resveratrol; Herba Epimedii extract; Radix Ginseng extract; Herba Lysimachiae extract; Herba Hedyotidis Diffusae extract; Herba Scutellariae Barbatae extract; Vitamin C is formed
Said prescription B is by the Fructus Crataegi extract; Radix Aucklandiae extract; Radix Astragali extract; Radix Clematidis extract; Fructus Jujubae extract; Radix Achyranthis Bidentatae extract; Dioscorea nipponica Mak. Ningpo Yam Rhizome extract; Ramulus Mori extract; Fructus Psoraleae extract; Radix Dipsaci extract; Radix Puerariae extract; Cortex Cinnamomi extract; Fructus Schisandrae Chinensis extrat; Radix Angelicae Sinensis extract; Rhizoma Chuanxiong extract; The Radix Paeoniae Rubra extract; Semen Persicae extract; Flos Carthami extract; Radix Polygoni Multiflori extract; Cortex Eucommiae extract; The Bulbus Fritillariae Cirrhosae extract; The radix linderae extract; The Radix Rehmanniae Preparata extract; The Fructus Hordei Germinatus extract; Fructus Ligustri Lucidi extract; Radix Bupleuri extract; Fructus Lycii extract; Fructus Evodiae extract; Rhizoma Anemarrhenae extract; Radix Asparagi extract; Herba Artemisiae Scopariae extract; Rhizoma Gastrodiae extract; Radix Morindae Officinalis extract; Oligochitosan; Radix Notoginseng powder is formed.
Further, said prescription A and prescription B are made up of the component of following weight portion,
Prescription A: prescription A: 70～130 parts of Eupolyphaga Seu Steleophaga extracts; 70～130 parts of Scorpio extract; 70～130 parts of Gekko Swinhonis extracts; 70～130 parts of Radix Morindae Officinalis extracts; 70～130 parts of Herba Cistanches extracts; 70～130 parts of Olibanum extract; 70～130 parts of Hirudo extracts; 70～130 parts of Radix Aconiti Lateralis Preparata extract; 70～130 parts of stir-baked SQUAMA MANITISs; 10～30 parts of Styrax; 10～30 parts of Benzoinumes; 10～30 parts of Borneolum Syntheticums; 250～350 parts of Scolopendra extracts; 5～15 parts in Moschus; 10～30 parts of Realgars; 3～9 parts of Venenum Bufoniss; 30～70 parts of artificial Calculus Boviss; 30～70 parts of Margarita powder; 70～130 parts of piece of antlers; 70～130 parts of Fructus Mume; 300～500 parts of Ganoderma spore powders; 70～130 parts of Semen Strychni (processed) powders; 150～250 parts of oligochitosans; 5～15 parts of Semen Vitis viniferae extracts; 30～70 parts of resveratrols; 70～130 parts of Herba Epimedii extracts; 70～130 parts of Radix Ginseng extracts; 70～130 parts of Herba Lysimachiae extracts; 200～400 parts of Herba Hedyotidis Diffusae extracts; 70～130 parts of Herba Scutellariae Barbatae extracts; 30～70 parts of vitamin Cs;
Prescription B: 70～130 parts of Fructus Crataegi extracts; 30～70 parts of Radix Aucklandiae extracts; 80～160 parts of Radix Astragali extracts; 15～45 parts of Radix Clematidis extracts; 15～45 parts of Fructus Jujubae extracts; 5～15 parts of Radix Achyranthis Bidentatae extracts; 5～15 parts of Dioscorea nipponica Mak. Ningpo Yam Rhizome extracts; 10～30 parts of Ramulus Mori extract; 5～15 parts of Fructus Psoraleae extracts; 5～15 parts of Radix Dipsaci extracts; 10～30 parts of Radix Puerariae extracts; 5～15 parts of Cortex Cinnamomi extracts; 15～45 parts of Fructus Schisandrae Chinensis extrats; 5～15 parts of Radix Angelicae Sinensis extracts; 5～15 parts of Rhizoma Chuanxiong extracts; 10～20 parts of Radix Paeoniae Rubra extracts; 5～15 parts in Semen Persicae extract; 5～15 parts of Flos Carthami extracts; 10～30 parts of Radix Polygoni Multiflori extracts; 10～30 parts of Cortex Eucommiae extract; 5～15 parts of Bulbus Fritillariae Cirrhosae extracts; 10～30 parts of radix linderae extracts; 15～45 parts of Radix Rehmanniae Preparata extracts; 15～45 parts of Fructus Hordei Germinatus extracts; 15～45 parts of Fructus Ligustri Lucidi extracts; 5～15 parts of Radix Bupleuri extracts; 15～45 parts of Fructus Lycii extracts; 5～15 parts of Fructus Evodiae extracts; 5～15 parts of Rhizoma Anemarrhenae extracts; 5～15 parts of Radix Asparagi extracts; 5～15 parts of Herba Artemisiae Scopariae extract; 5～15 parts of Rhizoma Gastrodiae extracts; 5～15 parts of Radix Morindae Officinalis extracts; 2～7 parts of oligochitosans; 2～7 parts of Radix Notoginseng powder.
Further, said prescription A and prescription B are made up of the component of following weight portion,
Prescription A: 100 parts of Eupolyphaga Seu Steleophaga extracts; 100 parts of Scorpio extract; 100 parts of Gekko Swinhonis extracts; 100 parts of Radix Morindae Officinalis extracts; 100 parts of Herba Cistanches extracts; Make fragrant 100 parts of newborn extract; 100 parts of Hirudo extracts; 100 parts of Radix Aconiti Lateralis Preparata extract; 100 parts of stir-baked SQUAMA MANITISs; 20 parts of Styrax; 20 parts of Benzoinumes; 20 parts of Borneolum Syntheticums; 300 parts of Scolopendra extracts; 10 parts in Moschus; 20 parts of Realgars; 6 parts of Venenum Bufoniss; 50 parts of artificial Calculus Boviss; 50 parts of Margarita powder; 100 parts of piece of antlers; 100 parts of Fructus Mume; 400 parts of Ganoderma spore powders; 100 parts of Semen Strychni (processed) powders; 200 parts of oligochitosans; 10 parts of Semen Vitis viniferae extracts; 50 parts of resveratrols; 100 parts of Herba Epimedii extracts; 100 parts of Radix Ginseng extracts; 100 parts of Herba Lysimachiae extracts; 300 parts of Herba Hedyotidis Diffusae extracts; 100 parts of Herba Scutellariae Barbatae extracts; 50 parts of vitamin Cs;
Prescription B: 100 parts of Fructus Crataegi extracts; 50 parts of Radix Aucklandiae extracts; 120 parts of Radix Astragali extracts; 30 parts of Radix Clematidis extracts; 30 parts of Fructus Jujubae extracts; 10 parts of Radix Achyranthis Bidentatae extracts; 10 parts of Dioscorea nipponica Mak. Ningpo Yam Rhizome extracts; 20 parts of Ramulus Mori extract; 10 parts of Fructus Psoraleae extracts; 10 parts of Radix Dipsaci extracts; 20 parts of Radix Puerariae extracts; 10 parts of Cortex Cinnamomi extracts; 30 parts of Fructus Schisandrae Chinensis extrats; 10 parts of Radix Angelicae Sinensis extracts; 10 parts of Rhizoma Chuanxiong extracts; 15 parts of Radix Paeoniae Rubra extracts; 10 parts in Semen Persicae extract; 10 parts of Flos Carthami extracts; 20 parts of Radix Polygoni Multiflori extracts; 20 parts of Cortex Eucommiae extract; 10 parts of Bulbus Fritillariae Cirrhosae extracts; 20 parts of radix linderae extracts; 30 parts of Radix Rehmanniae Preparata extracts; 30 parts of Fructus Hordei Germinatus extracts; 30 parts of Fructus Ligustri Lucidi extracts; 10 parts of Radix Bupleuri extracts; 30 parts of Fructus Lycii extracts; 10 parts of Fructus Evodiae extracts; 10 parts of Rhizoma Anemarrhenae extracts; 10 parts of Radix Asparagi extracts; 10 parts of Herba Artemisiae Scopariae extract; 10 parts of Rhizoma Gastrodiae extracts; 10 parts of Radix Morindae Officinalis extracts; 5 parts of oligochitosans; 5 parts of Radix Notoginseng powder.
The present invention also provides the above-mentioned method for preparing that is used to treat two prescription medicines of apoplectic hemiplegia, and this method mainly is made up of following steps:
(1) prepares various extracts among prescription A and the prescription B;
(2) all the other each components among prescription A and the prescription B are pulverized respectively;
(3) with each the component mix homogeneously among the prescription A, general ball makes 2～4mm piller, drying;
(4), process granule or add Mel and process honeyed pill with each the component mix homogeneously among the prescription B.
Further, cross 80 mesh sieves in the said step (2) among prescription A and the prescription B behind all the other each component pulverize separately.
Further, said extract obtains through following steps:
The material that (1) will extract is removed impurity;
(2) material that will remove impurity carries out pulverization process;
(3) ratio in 1Kg material and 10L water is put in it in extraction pot, refluxes 20～30 minutes, obtains extracting solution;
(4), concentrate this extracting solution with extracting solution suction concentration tank;
(5) the spray-dried extract that promptly makes of extracting solution after said the concentrating.
The present invention has the following advantages and beneficial effect:
1, prescription A of the present invention has the effect of YIN nourishing town liver; Prescription B has the effect of kidney tonifying, essence replenishing, tonifying both YIN and YANG; Two prescriptions are used can treat black arteries and veins (blood vessel) and the lung-pulse (nerve) simultaneously, to the heart (blood circulation), brain (nervous system) onset simultaneously;
2, the present invention has improved the treatment and the prevention level of apoplexy, has reduced sickness rate, disability rate and the mortality rate of apoplexy;
3, the present invention is applicable to various disease conditions such as apoplectic hemiplegia, cerebral blood supply insufficiency, brain atrophy, epilepsy, coronary heart disease, heart infarction, arrhythmia, hypertension;
4, total effective rate of the present invention is high, and cost is lower, is suitable for promoting.
The specific embodiment
Below in conjunction with embodiment the present invention is done to specify further, but embodiment of the present invention is not limited thereto.
Embodiment 1
Present embodiment is mainly formed through following steps:
At first, obtain the extract of various materials, extraction step is following:
The material that (1) will extract is removed impurity; Like the Eupolyphaga Seu Steleophaga extract, the medicinal part of Eupolyphaga Seu Steleophaga is taken out;
(2) material that will remove impurity carries out pulverization process; Promptly handle, it is crushed to 20 orders through pulverizer;
(3) ratio in 1Kg Eupolyphaga Seu Steleophaga and 10L water is put in it in extraction pot, refluxes 20～30 minutes, obtains extracting solution; Extracting temperature is about 100 ℃;
(4) with extracting solution suction concentration tank, concentrate this extracting solution, promptly adopt the conventional method for concentration of the field of Chinese medicines under 90 ℃ of left and right sides conditions, to concentrate this extracting solution;
(5) the spray-dried Eupolyphaga Seu Steleophaga extract that promptly makes of extracting solution after said the concentrating.
Various extracts all obtain through above method among prescription A and the prescription B.
Secondly, each component of non-extract among prescription A and the prescription B is pulverized respectively; Be crushed to its fineness smaller or equal to 80 orders.Can when pulverizing, cross 80 purposes sieve here, just sifted out smaller or equal to 80 purpose components, all the other compositions are proceeded to pulverize.Need pulverized component that stir-baked SQUAMA MANITIS, Styrax, Benzoinum, Borneolum Syntheticum, Moschus, Realgar, Venenum Bufonis, artificial Calculus Bovis, Margarita powder, piece of antler, Fructus Mume, Ganoderma spore powder, oligochitosan, resveratrol and vitamin C and oligochitosan and the Radix Notoginseng powder among the prescription B among the prescription A are arranged in the present embodiment.
Moreover; With 100 parts of Eupolyphaga Seu Steleophaga extracts among the prescription A, 100 parts of Scorpio extract, 100 parts of Gekko Swinhonis extracts, 100 parts of Radix Morindae Officinalis extracts, 100 parts of Herba Cistanches extracts, fragrant 100 parts of the newborn extract of system, 100 parts of Hirudo extracts, 100 parts of Radix Aconiti Lateralis Preparata extract, 100 parts of stir-baked SQUAMA MANITISs, 20 parts of Styrax, 20 parts of Benzoinumes, 20 parts of Borneolum Syntheticums, 300 parts of Scolopendra extracts, 10 parts in Moschus, 20 parts of Realgars, 6 parts of Venenum Bufoniss, 50 parts of artificial Calculus Boviss, 50 parts of Margarita powder, 100 parts of piece of antlers, 100 parts of Fructus Mume, 400 parts of Ganoderma spore powders, 100 parts of Semen Strychni (processed) powders, 200 parts of oligochitosans, 10 parts of Semen Vitis viniferae extracts, 50 parts of resveratrols, 100 parts of Herba Epimedii extracts, 100 parts of Radix Ginseng extracts, 100 parts of Herba Lysimachiae extracts, 300 parts of Herba Hedyotidis Diffusae extracts, 100 parts of Herba Scutellariae Barbatae extracts and 50 parts of mix homogeneously of vitamin C, general ball after drying makes the piller that diameter is 3mm.
Above-mentioned Semen Strychni (processed) powder is through the special process manufacturing, and the method for preparing of Semen Strychni (processed) powder is following: Semen Strychni water logging QUMAO, dry, and put in the Oleum Sesami fried.In concocting process, pull out at once when going up pasta when Semen Strychni is floating.The Semen Strychni of fried mistake is added suitable quantity of water again, and add an amount of flour, pull Semen Strychni out after boiling, clear water is cleaned, and dries.The reuse dry flour mixes with the drying in the sun Semen Strychni, places seven days in shady and cool dry place.Clean flour with clear water, pull Semen Strychni out and dry.Pulverized 10 mesh sieves, the coarse powder after the pulverizing is divided on medicated napkin, very thin shop one deck, and the reuse medicated napkin covers.Place at shady and cool dry place, changes medicated napkin every day, till not having oil absorption on the medicated napkin, pulverized 80 mesh sieves again, and the shady and cool dry place of fine powder deposits subsequent use.
At last, with each the component mix homogeneously among the prescription B, process granule or add Mel and process honeyed pill.Present embodiment is with 100 parts of Fructus Crataegi extracts, 50 parts of Radix Aucklandiae extracts, 120 parts of Radix Astragali extracts, 30 parts of Radix Clematidis extracts, 30 parts of Fructus Jujubae extracts, 10 parts of Radix Achyranthis Bidentatae extracts, 10 parts of Dioscorea nipponica Mak. Ningpo Yam Rhizome extracts, 20 parts of Ramulus Mori extract, 10 parts of Fructus Psoraleae extracts, 10 parts of Radix Dipsaci extracts, 20 parts of Radix Puerariae extracts, 10 parts of Cortex Cinnamomi extracts, 30 parts of Fructus Schisandrae Chinensis extrats, 10 parts of Radix Angelicae Sinensis extracts, 10 parts of Rhizoma Chuanxiong extracts, 15 parts of Radix Paeoniae Rubra extracts, 10 parts in Semen Persicae extract, 10 parts of Flos Carthami extracts, 20 parts of Radix Polygoni Multiflori extracts, 20 parts of Cortex Eucommiae extract, 10 parts of Bulbus Fritillariae Cirrhosae extracts, 20 parts of radix linderae extracts, 30 parts of Radix Rehmanniae Preparata extracts, 30 parts of Fructus Hordei Germinatus extracts, 30 parts of Fructus Ligustri Lucidi extracts, 10 parts of Radix Bupleuri extracts, 30 parts of Fructus Lycii extracts, 10 parts of Fructus Evodiae extracts, 10 parts of Rhizoma Anemarrhenae extracts, 10 parts of Radix Asparagi extracts, 10 parts of Herba Artemisiae Scopariae extract, 10 parts of Rhizoma Gastrodiae extracts, 10 parts of Radix Morindae Officinalis extracts, 5 parts of oligochitosans, 5 parts of mix homogeneously of Radix Notoginseng powder, obtains the granule of every bag 3g through method of granulating granulation, drying, the granulate of conventional Chinese medicine.Present embodiment can also adopt the known honeyed pill manufacturing approach of industry with the component mix homogeneously of above weight portion among the prescription B, adds an amount of Mel and processes the honeyed pill that weight is 3g.
Embodiment 2
Present embodiment only is that with the difference of embodiment 1 weight portion of each component is different.
Prescription A: 77 parts of Eupolyphaga Seu Steleophaga extracts; 122 parts of Scorpio extract; 110 parts of Gekko Swinhonis extracts; 130 parts of Radix Morindae Officinalis extracts; 75 parts of Herba Cistanches extracts; 88 parts of Olibanum extract; 95 parts of Hirudo extracts; 105 parts of Radix Aconiti Lateralis Preparata extract; 110 parts of stir-baked SQUAMA MANITISs; 23 parts of Styrax; 26 parts of Benzoinumes; 13 parts of Borneolum Syntheticums; 290 parts of Scolopendra extracts; 7 parts in Moschus; 15 parts of Realgars; 4 parts of Venenum Bufoniss; 60 parts of artificial Calculus Boviss; 60 parts of Margarita powder; 105 parts of piece of antlers; 110 parts of Fructus Mume; 450 parts of Ganoderma spore powders; 110 parts of Semen Strychni (processed) powders; 230 parts of oligochitosans; 13 parts of Semen Vitis viniferae extracts; 45 parts of resveratrols; 75 parts of Herba Epimedii extracts; 125 parts of Radix Ginseng extracts; 130 parts of Herba Lysimachiae extracts; 350 parts of Herba Hedyotidis Diffusae extracts; 120 parts of Herba Scutellariae Barbatae extracts; 45 parts of vitamin Cs;
Prescription B: 88 parts of Fructus Crataegi extracts; 55 parts of Radix Aucklandiae extracts; 150 parts of Radix Astragali extracts; 30 parts of Radix Clematidis extracts; 15 parts of Fructus Jujubae extracts; 13 parts of Radix Achyranthis Bidentatae extracts; 7 parts of Dioscorea nipponica Mak. Ningpo Yam Rhizome extracts; 22 parts of Ramulus Mori extract; 6 parts of Fructus Psoraleae extracts; 13 parts of Radix Dipsaci extracts; 28 parts of Radix Puerariae extracts; 11 parts of Cortex Cinnamomi extracts; 19 parts of Fructus Schisandrae Chinensis extrats; 7 parts of Radix Angelicae Sinensis extracts; 8 parts of Rhizoma Chuanxiong extracts; 11 parts of Radix Paeoniae Rubra extracts; 13 parts in Semen Persicae extract; 12 parts of Flos Carthami extracts; 14 parts of Radix Polygoni Multiflori extracts; 15 parts of Cortex Eucommiae extract; 11 parts of Bulbus Fritillariae Cirrhosae extracts; 27 parts of radix linderae extracts; 40 parts of Radix Rehmanniae Preparata extracts; 35 parts of Fructus Hordei Germinatus extracts; 17 parts of Fructus Ligustri Lucidi extracts; 9 parts of Radix Bupleuri extracts; 16 parts of Fructus Lycii extracts; 13 parts of Fructus Evodiae extracts; 7 parts of Rhizoma Anemarrhenae extracts; 6 parts of Radix Asparagi extracts; 11 parts of Herba Artemisiae Scopariae extract; 13 parts of Rhizoma Gastrodiae extracts; 7 parts of Radix Morindae Officinalis extracts; 6 parts of oligochitosans; 4 parts of Radix Notoginseng powder.
Embodiment 3
Present embodiment only is that with the difference of embodiment 1 weight portion of each component is different.
Prescription A: 120 parts of Eupolyphaga Seu Steleophaga extracts; 75 parts of Scorpio extract; 90 parts of Gekko Swinhonis extracts; 80 parts of Radix Morindae Officinalis extracts; 115 parts of Herba Cistanches extracts; 125 parts of Olibanum extract; 105 parts of Hirudo extracts; 90 parts of Radix Aconiti Lateralis Preparata extract; 85 parts of stir-baked SQUAMA MANITISs; 15 parts of Styrax; 26 parts of Benzoinumes; 13 parts of Borneolum Syntheticums; 290 parts of Scolopendra extracts; 7 parts in Moschus; 15 parts of Realgars; 4 parts of Venenum Bufoniss; 60 parts of artificial Calculus Boviss; 60 parts of Margarita powder; 105 parts of piece of antlers; 110 parts of Fructus Mume; 450 parts of Ganoderma spore powders; 110 parts of Semen Strychni (processed) powders; 230 parts of oligochitosans; 13 parts of Semen Vitis viniferae extracts; 45 parts of resveratrols; 75 parts of Herba Epimedii extracts; 125 parts of Radix Ginseng extracts; 130 parts of Herba Lysimachiae extracts; 350 parts of Herba Hedyotidis Diffusae extracts; 120 parts of Herba Scutellariae Barbatae extracts; 45 parts of vitamin Cs;
Prescription B: 88 parts of Fructus Crataegi extracts; 55 parts of Radix Aucklandiae extracts; 150 parts of Radix Astragali extracts; 30 parts of Radix Clematidis extracts; 15 parts of Fructus Jujubae extracts; 13 parts of Radix Achyranthis Bidentatae extracts; 7 parts of Dioscorea nipponica Mak. Ningpo Yam Rhizome extracts; 22 parts of Ramulus Mori extract; 6 parts of Fructus Psoraleae extracts; 13 parts of Radix Dipsaci extracts; 28 parts of Radix Puerariae extracts; 11 parts of Cortex Cinnamomi extracts; 19 parts of Fructus Schisandrae Chinensis extrats; 7 parts of Radix Angelicae Sinensis extracts; 8 parts of Rhizoma Chuanxiong extracts; 11 parts of Radix Paeoniae Rubra extracts; 13 parts in Semen Persicae extract; 12 parts of Flos Carthami extracts; 14 parts of Radix Polygoni Multiflori extracts; 15 parts of Cortex Eucommiae extract; 11 parts of Bulbus Fritillariae Cirrhosae extracts; 27 parts of radix linderae extracts; 40 parts of Radix Rehmanniae Preparata extracts; 35 parts of Fructus Hordei Germinatus extracts; 17 parts of Fructus Ligustri Lucidi extracts; 9 parts of Radix Bupleuri extracts; 16 parts of Fructus Lycii extracts; 13 parts of Fructus Evodiae extracts; 7 parts of Rhizoma Anemarrhenae extracts; 6 parts of Radix Asparagi extracts; 11 parts of Herba Artemisiae Scopariae extract; 13 parts of Rhizoma Gastrodiae extracts; 7 parts of Radix Morindae Officinalis extracts; 6 parts of oligochitosans; 4 parts of Radix Notoginseng powder.
Instructions of taking:
Taking-up makes honeyed pill 1～3 ball or granule 1～3 bag according to prescription B, uses the eliminating cold for resuscitation broken off by water flush; Get piller 5～10g that the diameter that makes according to prescription A is 3mm again, B is used with prescription, every day three times, takes more than 6 months.Its dosage of taking can be adjusted according to patient's practical situation.In above embodiment, all adopt honeyed pill 1～3 ball that prescription B is made to use the eliminating cold for resuscitation broken off by water flush, when tea is drunk, and to take the diameter that prescription A makes simultaneously be piller 5～10g of 3mm, every day three times, takes and got final product in 6 months.
Detection method is following:
The present invention picks out 90 routine cerebral thrombosiss and cerebral hemorrhage patient, and cerebral thrombosis and cerebral hemorrhage patient's clinical symptoms is hemiplegia, dysphasia, disturbance of consciousness etc.The patient of present embodiment takes the honeyed pill that 1～3 ball prescription B of eliminating cold for resuscitation broken off by water flush makes, and takes piller 5～10g that prescription A makes simultaneously, every day three times, takes 6 months.
After 6 months above patient is detected, symptoms such as hemiplegia, dysphasia, disturbance of consciousness obviously make moderate progress, and total effective rate has reached 96.7%.
According to above scheme, just can well realize the present invention.
Claims (6)
1. the two prescription medicines that are used to treat apoplectic hemiplegia is characterized in that, said medicine is made up of the prescription A of 5～10 weight portions and the prescription B of 3～9 weight portions,
Said prescription A is by the Eupolyphaga Seu Steleophaga extract; Scorpio extract; The Gekko Swinhonis extract; Scolopendra extract; The Radix Morindae Officinalis extract; Herba Cistanches extract; Olibanum extract; Hirudo extract; Radix Aconiti Lateralis Preparata extract; Stir-baked SQUAMA MANITIS; Styrax; Benzoinum; Borneolum Syntheticum; Moschus; Realgar; Venenum Bufonis; The artificial Calculus Bovis; Margarita powder; Piece of antler; Fructus Mume; Ganoderma spore powder; Semen Strychni (processed) powder; Oligochitosan; Semen Vitis viniferae extract; Resveratrol; Herba Epimedii extract; Radix Ginseng extract; Herba Lysimachiae extract; Herba Hedyotidis Diffusae extract; Herba Scutellariae Barbatae extract; Vitamin C is formed
Said prescription B is by the Fructus Crataegi extract; Radix Aucklandiae extract; Radix Astragali extract; Radix Clematidis extract; Fructus Jujubae extract; Radix Achyranthis Bidentatae extract; Dioscorea nipponica Mak. Ningpo Yam Rhizome extract; Ramulus Mori extract; Fructus Psoraleae extract; Radix Dipsaci extract; Radix Puerariae extract; Cortex Cinnamomi extract; Fructus Schisandrae Chinensis extrat; Radix Angelicae Sinensis extract; Rhizoma Chuanxiong extract; The Radix Paeoniae Rubra extract; Semen Persicae extract; Flos Carthami extract; Radix Polygoni Multiflori extract; Cortex Eucommiae extract; The Bulbus Fritillariae Cirrhosae extract; The radix linderae extract; The Radix Rehmanniae Preparata extract; The Fructus Hordei Germinatus extract; Fructus Ligustri Lucidi extract; Radix Bupleuri extract; Fructus Lycii extract; Fructus Evodiae extract; Rhizoma Anemarrhenae extract; Radix Asparagi extract; Herba Artemisiae Scopariae extract; Rhizoma Gastrodiae extract; Radix Morindae Officinalis extract; Oligochitosan; Radix Notoginseng powder is formed.
2. a kind of two prescription medicines that are used to treat apoplectic hemiplegia according to claim 1 is characterized in that said prescription A and prescription B are made up of the component of following weight portion,
Prescription A: 70～130 parts of Eupolyphaga Seu Steleophaga extracts; 70～130 parts of Scorpio extract; 70～130 parts of Gekko Swinhonis extracts; 70～130 parts of Radix Morindae Officinalis extracts; 70～130 parts of Herba Cistanches extracts; 70～130 parts of Olibanum extract; 70～130 parts of Hirudo extracts; 70～130 parts of Radix Aconiti Lateralis Preparata extract; 70～130 parts of stir-baked SQUAMA MANITISs; 10～30 parts of Styrax; 10～30 parts of Benzoinumes; 10～30 parts of Borneolum Syntheticums; 250～350 parts of Scolopendra extracts; 5～15 parts in Moschus; 10～30 parts of Realgars; 3～9 parts of Venenum Bufoniss; 30～70 parts of artificial Calculus Boviss; 30～70 parts of Margarita powder; 70～130 parts of piece of antlers; 70～130 parts of Fructus Mume; 300～500 parts of Ganoderma spore powders; 70～130 parts of Semen Strychni (processed) powders; 150～250 parts of oligochitosans; 5～15 parts of Semen Vitis viniferae extracts; 30～70 parts of resveratrols; 70～130 parts of Herba Epimedii extracts; 70～130 parts of Radix Ginseng extracts; 70～130 parts of Herba Lysimachiae extracts; 200～400 parts of Herba Hedyotidis Diffusae extracts; 70～130 parts of Herba Scutellariae Barbatae extracts; 30～70 parts of vitamin Cs;
Prescription B: 70～130 parts of Fructus Crataegi extracts; 30～70 parts of Radix Aucklandiae extracts; 80～160 parts of Radix Astragali extracts; 15～45 parts of Radix Clematidis extracts; 15～45 parts of Fructus Jujubae extracts; 5～15 parts of Radix Achyranthis Bidentatae extracts; 5～15 parts of Dioscorea nipponica Mak. Ningpo Yam Rhizome extracts; 10～30 parts of Ramulus Mori extract; 5～15 parts of Fructus Psoraleae extracts; 5～15 parts of Radix Dipsaci extracts; 10～30 parts of Radix Puerariae extracts; 5～15 parts of Cortex Cinnamomi extracts; 15～45 parts of Fructus Schisandrae Chinensis extrats; 5～15 parts of Radix Angelicae Sinensis extracts; 5～15 parts of Rhizoma Chuanxiong extracts; 10～20 parts of Radix Paeoniae Rubra extracts; 5～15 parts in Semen Persicae extract; 5～15 parts of Flos Carthami extracts; 10～30 parts of Radix Polygoni Multiflori extracts; 10～30 parts of Cortex Eucommiae extract; 5～15 parts of Bulbus Fritillariae Cirrhosae extracts; 10～30 parts of radix linderae extracts; 15～45 parts of Radix Rehmanniae Preparata extracts; 15～45 parts of Fructus Hordei Germinatus extracts; 15～45 parts of Fructus Ligustri Lucidi extracts; 5～15 parts of Radix Bupleuri extracts; 15～45 parts of Fructus Lycii extracts; 5～15 parts of Fructus Evodiae extracts; 5～15 parts of Rhizoma Anemarrhenae extracts; 5～15 parts of Radix Asparagi extracts; 5～15 parts of Herba Artemisiae Scopariae extract; 5～15 parts of Rhizoma Gastrodiae extracts; 5～15 parts of Radix Morindae Officinalis extracts; 2～7 parts of oligochitosans; 2～7 parts of Radix Notoginseng powder.
3. a kind of two prescription medicines that are used to treat apoplectic hemiplegia according to claim 2 is characterized in that said prescription A and prescription B are made up of the component of following weight portion,
Prescription A: 100 parts of Eupolyphaga Seu Steleophaga extracts; 100 parts of Scorpio extract; 100 parts of Gekko Swinhonis extracts; 100 parts of Radix Morindae Officinalis extracts; 100 parts of Herba Cistanches extracts; Make fragrant 100 parts of newborn extract; 100 parts of Hirudo extracts; 100 parts of Radix Aconiti Lateralis Preparata extract; 100 parts of stir-baked SQUAMA MANITISs; 20 parts of Styrax; 20 parts of Benzoinumes; 20 parts of Borneolum Syntheticums; 300 parts of Scolopendra extracts; 10 parts in Moschus; 20 parts of Realgars; 6 parts of Venenum Bufoniss; 50 parts of artificial Calculus Boviss; 50 parts of Margarita powder; 100 parts of piece of antlers; 100 parts of Fructus Mume; 400 parts of Ganoderma spore powders; 100 parts of Semen Strychni (processed) powders; 200 parts of oligochitosans; 10 parts of Semen Vitis viniferae extracts; 50 parts of resveratrols; 100 parts of Herba Epimedii extracts; 100 parts of Radix Ginseng extracts; 100 parts of Herba Lysimachiae extracts; 300 parts of Herba Hedyotidis Diffusae extracts; 100 parts of Herba Scutellariae Barbatae extracts; 50 parts of vitamin Cs;
Prescription B: 100 parts of Fructus Crataegi extracts; 50 parts of Radix Aucklandiae extracts; 120 parts of Radix Astragali extracts; 30 parts of Radix Clematidis extracts; 30 parts of Fructus Jujubae extracts; 10 parts of Radix Achyranthis Bidentatae extracts; 10 parts of Dioscorea nipponica Mak. Ningpo Yam Rhizome extracts; 20 parts of Ramulus Mori extract; 10 parts of Fructus Psoraleae extracts; 10 parts of Radix Dipsaci extracts; 20 parts of Radix Puerariae extracts; 10 parts of Cortex Cinnamomi extracts; 30 parts of Fructus Schisandrae Chinensis extrats; 10 parts of Radix Angelicae Sinensis extracts; 10 parts of Rhizoma Chuanxiong extracts; 15 parts of Radix Paeoniae Rubra extracts; 10 parts in Semen Persicae extract; 10 parts of Flos Carthami extracts; 20 parts of Radix Polygoni Multiflori extracts; 20 parts of Cortex Eucommiae extract; 10 parts of Bulbus Fritillariae Cirrhosae extracts; 20 parts of radix linderae extracts; 30 parts of Radix Rehmanniae Preparata extracts; 30 parts of Fructus Hordei Germinatus extracts; 30 parts of Fructus Ligustri Lucidi extracts; 10 parts of Radix Bupleuri extracts; 30 parts of Fructus Lycii extracts; 10 parts of Fructus Evodiae extracts; 10 parts of Rhizoma Anemarrhenae extracts; 10 parts of Radix Asparagi extracts; 10 parts of Herba Artemisiae Scopariae extract; 10 parts of Rhizoma Gastrodiae extracts; 10 parts of Radix Morindae Officinalis extracts; 5 parts of oligochitosans; 5 parts of Radix Notoginseng powder.
4. being used to described in the claim 1～3 treated the method for preparing of two prescription medicines of apoplectic hemiplegia, it is characterized in that, mainly is made up of following steps:
(1) prepares various extracts among prescription A and the prescription B;
(2) all the other each components among prescription A and the prescription B are pulverized respectively;
(3) with each the component mix homogeneously among the prescription A, general ball makes 2～4mm piller, drying;
(4), process granule or add Mel and process honeyed pill with each the component mix homogeneously among the prescription B.
5. the method for preparing that is used to treat two prescription medicines of apoplectic hemiplegia according to claim 4 is characterized in that, mistake 80 mesh sieves behind all the other each component pulverize separately among prescription A and the prescription B in the said step (2).
6. according to claim 4 or the 5 described method for preparinies that are used to treat two prescription medicines of apoplectic hemiplegia, it is characterized in that said extract obtains through following steps:
The material that (1) will extract is removed impurity;
(2) material that will remove impurity carries out pulverization process;
(3) ratio in 1Kg material and 10L water is put in it in extraction pot, refluxes 20～30 minutes, obtains extracting solution;
(4), concentrate this extracting solution with extracting solution suction concentration tank;
(5) the spray-dried extract that promptly makes of extracting solution after said the concentrating.
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| CN103417790A (en) * | 2013-07-31 | 2013-12-04 | 泰山医学院 | Traditional Chinese medicine for treatment of cerebral hemorrhage |
| CN106942561A (en) * | 2017-05-02 | 2017-07-14 | 陈霞 | A kind of beverage composition for treating dental erosion and preparation method and application |
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| CN103041061A (en) * | 2013-01-18 | 2013-04-17 | 崔苡菱 | Stasis-dissolving and pulse-invigorating powder |
| CN103041061B (en) * | 2013-01-18 | 2015-01-07 | 崔苡菱 | Stasis-dissolving and pulse-invigorating powder |
| CN103417790A (en) * | 2013-07-31 | 2013-12-04 | 泰山医学院 | Traditional Chinese medicine for treatment of cerebral hemorrhage |
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| CN106942561A (en) * | 2017-05-02 | 2017-07-14 | 陈霞 | A kind of beverage composition for treating dental erosion and preparation method and application |
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Free format text: CORRECT: INVENTOR; FROM: YU ZEMIN LIU FANG ZHENG YING LIU YUQIN LIU ZHIGANG TO: LU CHENGXIAN TIAN JIANHONG CHE SHANGZE |
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| CP01 | Change in the name or title of a patent holder |
Address after: 614200 processing and warehousing logistics park, Hongxing Industrial Zone, victory Town, Mount Emei, Leshan, Sichuan Patentee after: EMEISHAN HONGSHENG PHARMACEUTICAL CO.,LTD. Address before: 614200 processing and warehousing logistics park, Hongxing Industrial Zone, victory Town, Mount Emei, Leshan, Sichuan Patentee before: EMEISHAN TLS PHARMACEUTICAL Co.,Ltd. |
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| C53 | Correction of patent of invention or patent application | ||
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Inventor after: Yu Zemin Inventor after: Liu Fang Inventor after: Zheng Ying Inventor after: Liu Yuqin Inventor after: Liu Zhigang Inventor before: Lu Chengxian Inventor before: Tian Jianhong Inventor before: Che Shangze |
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| COR | Change of bibliographic data |
Free format text: CORRECT: INVENTOR; FROM: LU CHENGXIAN TIAN JIANHONG CHE SHANGZE TO: YU ZEMIN LIU FANG ZHENG YING LIU YUQIN LIU ZHIGANG |
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| PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
| PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: A kind of double prescription medicine for treating stroke and hemiplegia and preparation method thereof Effective date of registration: 20220808 Granted publication date: 20140402 Pledgee: Bank of China Co., Ltd. Emeishan Sub-branch Pledgor: EMEISHAN HONGSHENG PHARMACEUTICAL CO.,LTD. Registration number: Y2022980012099 |