CN102423441A - Double-formula medicine used for treating constipation, and preparation method thereof - Google Patents

Double-formula medicine used for treating constipation, and preparation method thereof Download PDF

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CN102423441A
CN102423441A CN201110441847XA CN201110441847A CN102423441A CN 102423441 A CN102423441 A CN 102423441A CN 201110441847X A CN201110441847X A CN 201110441847XA CN 201110441847 A CN201110441847 A CN 201110441847A CN 102423441 A CN102423441 A CN 102423441A
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parts
extract
extracts
radix
prescription
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余泽民
刘芳
郑鹰
刘玉琴
刘志刚
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EMEISHAN TLS PHARMACEUTICAL Co Ltd
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EMEISHAN TLS PHARMACEUTICAL Co Ltd
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Abstract

The invention discloses a double-formula medicine used for treating constipation, and a preparation method thereof. The double-formula medicine provided by the invention is composed by a formula A and a formula B. The formula A is composed of a Tiantai radix linderae extract, a corydalis tuber extract, panax notoginseng powder, a Chinese clematis root and rhizome extract, black common monkshood daughter root, an eucommia extract, and the like. The formula B is composed of a raw hawthorn extract, a costus root extract, a Mongolian milkvetch root extract, a salvia miltiorrhiza extract, a pilose asiabell root extract, an euonymus alatus extract, a Chinese clematis root and rhizome extract, a red date extract, and the like. The invention also provides a preparation method of the double-formula medicine. The medicine provided by the invention is advantaged in an integrated intestine and stomach regulation function, and less adverse reactions. With the medicine, reoccurrence of constipation can hardly happen.

Description

A kind of two prescription medicines that are used to treat constipation and preparation method thereof
Technical field
What the present invention relates to is a kind of Chinese medicine composition of treating constipation, specifically is meant a kind of two prescription medicines that use Chinese herbal medicine as raw material treatment constipation, the invention still further relates to the method for preparing of this medicine.
Background technology
Constipation is a kind of common disease, is meant difficult defecation, and defecation frequency reduces, or defecation feels not to the utmost, and with abdominal distention, stomachache, feel sick, poor appetite, rectal tenesmus, symptom such as vexed.Though the clinical branch card of constipation is complicated, two big types of not outer deficiency and excesss.Reality person is by pathogenic heat, and cold long-pending, the stagnation of QI causes evil indigestion intestinal, obstruction; It is gentle that void person causes intestinal to lose by the yang blood and qi deficiency, promotes unable.All be to form by large intestine conduction dereliction of duty.Its sick position is at large intestine, and is often relevant with internal organs such as taste lung Liver and kidney again.On method of treatment, real person should remove heat by catharsis, and empty person Yi Run mends, and should note identification of etiology according to differenciation of symptoms and signs, examines because of opinion and controls, and can not only rely on the obstructed and catharsis in the lump of dry stool.Since treatment constipation at present still with Drug therapy as most popular method, so that the choose reasonable medication seems is particularly important.Clinical drug therapy is many now is main to rush down, and cathartic is prone to the cathartic colon and cathartic relies on but take for a long time, even melanosis coli, thereby increases the weight of the state of an illness.
Summary of the invention
The object of the invention provides can integrally-regulated gastrointestinal function, the treatment back is difficult for repeatedly, side reaction is few a kind of two prescription medicines that are used to treat constipation and preparation method thereof.
Realize that technical scheme of the present invention is following: a kind of two prescription medicines that are used to treat constipation, said medicine is made up of the prescription A of 5~10 weight portions and the prescription B of 3~9 weight portions,
Said prescription A is by the radix linderae extract; Radix Salviae Miltiorrhizae extract; The Rhizoma Corydalis extract; Radix Notoginseng powder; Radix Clematidis extract; Radix Aconiti Lateralis Preparata; Cortex Eucommiae extract; Radix Achyranthis Bidentatae extract; Radix Bupleuri extract; Rhizoma Chuanxiong extract; Oletum Trogopterori; Margarita powder; The artificial Calculus Bovis; Borneolum Syntheticum; Ganoderma spore powder; Radix Sophorae Flavescentis extract; Oligochitosan; Semen Vitis viniferae extract; Resveratrol extract; Radix Ginseng extract; Herba Epimedii extract; Herba Lysimachiae extract; Herba Hedyotidis Diffusae extract; Herba Scutellariae Barbatae extract and vitamin C are formed
Said prescription B is by the Fructus Crataegi extract; Radix Aucklandiae extract; Radix Astragali extract; Radix Salviae Miltiorrhizae extract; Radix Codonopsis extract; Ramulus euonymi extract; Radix Clematidis extract; Fructus Jujubae extract; Radix Achyranthis Bidentatae extract; Rhizoma Atractylodis Macrocephalae extract; Rhizoma Smilacis Glabrae extract; Cortex Cinnamomi extract; Radix Angelicae Sinensis extract; Rhizoma Chuanxiong extract; The Radix Paeoniae Rubra extract; Semen Persicae extract; Flos Carthami extract; Radix Polygoni Multiflori extract; The Caulis Polygoni Multiflori extract; Cortex Eucommiae extract; The Bulbus Fritillariae Cirrhosae extract; The radix linderae extract; Radix Rehmanniae extract; Fructus Ligustri Lucidi extract; The Fructus Hordei Germinatus extract; Fructus Schisandrae Chinensis extrat; Fructus Lycii extract; Fructus Evodiae extract; Fructus Mume; Rhizoma Anemarrhenae extract; The Radix Asparagi extract; Radix Ophiopogonis extract; Radix Morindae Officinalis extract and oligochitosan are formed.
In order better to realize the present invention, said prescription A and prescription B are made up of the component of following weight portion,
Prescription A: 1~4 part of radix linderae extract; 1~4 part of Radix Salviae Miltiorrhizae extract; 1~4 part of Rhizoma Corydalis extract; 1~4 part of Radix Notoginseng powder; 1~4 part of Radix Clematidis extract; 1~4 part of Radix Aconiti Lateralis Preparata; 1~4 part of Cortex Eucommiae extract; 1~4 part of Radix Achyranthis Bidentatae extract; 1~4 part of Radix Bupleuri extract; 1~4 part of Rhizoma Chuanxiong extract; 1~4 part of Oletum Trogopterori; 1~4 part of Margarita powder; 1~4 part of artificial Calculus Bovis; 1~3 part of Borneolum Syntheticum; 10~25 parts of Ganoderma spore powders; 4~12 parts of oligochitosans; 1~4 part of Radix Sophorae Flavescentis extract; 1~3 part of Semen Vitis viniferae extract; 1~4 part of resveratrol extract; 3~9 parts of Radix Ginseng extracts; 3~9 parts of Herba Epimedii extracts; 5~15 parts of Herba Lysimachiae extracts; 10~30 parts of Herba Hedyotidis Diffusae extracts; 5~15 parts of Herba Scutellariae Barbatae extracts; 1~4 part of vitamin C
Prescription B: 10~30 parts of Fructus Crataegi extracts; 5~15 parts of Radix Aucklandiae extracts; 6~18 parts of Radix Astragali extracts; 1~4 part of Radix Salviae Miltiorrhizae extract; 1~4 part of Radix Codonopsis extract; 3~9 parts of Ramulus euonymi extracts; 2~6 parts of Radix Clematidis extracts; 3~9 parts of Fructus Jujubae extracts; 1~4 part of Radix Achyranthis Bidentatae extract; 2~6 parts of Rhizoma Atractylodis Macrocephalae extracts; 2~6 parts of Rhizoma Smilacis Glabrae extracts; 1~4 part of Cortex Cinnamomi extract; 1~4 part of Radix Angelicae Sinensis extract; 1~4 part of Rhizoma Chuanxiong extract; 2~5 parts of Radix Paeoniae Rubra extracts; 1~4 part in Semen Persicae extract; 1~4 part of Flos Carthami extract; 1~4 part of Radix Polygoni Multiflori extract; 3~9 parts of Caulis Polygoni Multiflori extracts; 2~6 parts of Cortex Eucommiae extract; 1~4 part of Bulbus Fritillariae Cirrhosae extract; 2~6 parts of radix linderae extracts; 1~4 part of Radix Rehmanniae extract; 3~9 parts of Fructus Ligustri Lucidi extracts; 3~9 parts of Fructus Hordei Germinatus extracts; 2~6 parts of Fructus Schisandrae Chinensis extrats; 3~9 parts of Fructus Lycii extracts; 2~5 parts of Fructus Evodiae extracts; 1~4 part of Fructus Mume; 1~4 part of Rhizoma Anemarrhenae extract; 1~4 part of Radix Asparagi extract; 1~4 part of Radix Ophiopogonis extract; 1~4 part of Radix Morindae Officinalis extract; 1~4 part of oligochitosan.
As the weight portion of optimum, said prescription A and prescription B are made up of the component of following weight portion,
Prescription A: 2 parts of radix linderae extracts; 2 parts of Radix Salviae Miltiorrhizae extracts; 2 parts of Rhizoma Corydalis extracts; 2 parts of Radix Notoginseng powder; 2 parts of Radix Clematidis extracts; 2 parts of Radix Aconiti Lateralis Preparatas; 2 parts of Cortex Eucommiae extract; 2 parts of Radix Achyranthis Bidentatae extracts; 2 parts of Radix Bupleuri extracts; 2 parts of Rhizoma Chuanxiong extracts; 2 parts of Oletum Trogopteroris; 2 parts of Margarita powder; 2 parts of artificial Calculus Boviss; 1 part of Borneolum Syntheticum; 16 parts of Ganoderma spore powders; 8 parts of oligochitosans; 2 parts of Radix Sophorae Flavescentis extracts; 1 part of Semen Vitis viniferae extract; 2 parts of resveratrol extracts; 6 parts of Radix Ginseng extracts; 6 parts of Herba Epimedii extracts; 10 parts of Herba Lysimachiae extracts; 20 parts of Herba Hedyotidis Diffusae extracts; 10 parts of Herba Scutellariae Barbatae extracts; 2 parts of vitamin Cs
Prescription B: 20 parts of Fructus Crataegi extracts; 10 parts of Radix Aucklandiae extracts; 12 parts of Radix Astragali extracts; 2 parts of Radix Salviae Miltiorrhizae extracts; 2 parts of Radix Codonopsis extracts; 6 parts of Ramulus euonymi extracts; 4 parts of Radix Clematidis extracts; 6 parts of Fructus Jujubae extracts; 2 parts of Radix Achyranthis Bidentatae extracts; 4 parts of Rhizoma Atractylodis Macrocephalae extracts; 4 parts of Rhizoma Smilacis Glabrae extracts; 2 parts of Cortex Cinnamomi extracts; 2 parts of Radix Angelicae Sinensis extracts; 2 parts of Rhizoma Chuanxiong extracts; 3 parts of Radix Paeoniae Rubra extracts; 2 parts in Semen Persicae extract; 2 parts of Flos Carthami extracts; 2 parts of Radix Polygoni Multiflori extracts; 6 parts of Caulis Polygoni Multiflori extracts; 4 parts of Cortex Eucommiae extract; 2 parts of Bulbus Fritillariae Cirrhosae extracts; 4 parts of radix linderae extracts; 2 parts of Radix Rehmanniae extracts; 6 parts of Fructus Ligustri Lucidi extracts; 6 parts of Fructus Hordei Germinatus extracts; 4 parts of Fructus Schisandrae Chinensis extrats; 6 parts of Fructus Lycii extracts; 3 parts of Fructus Evodiae extracts; 2 parts of Fructus Mume; 2 parts of Rhizoma Anemarrhenae extracts; 2 parts of Radix Asparagi extracts; 2 parts of Radix Ophiopogonis extracts; 2 parts of Radix Morindae Officinalis extracts; 2 parts of oligochitosans.
The method of the above two prescription medicines of preparation, mainly form by following steps:
(1) prepares various extracts among prescription A and the prescription B;
(2) all the other each components among prescription A and the prescription B are pulverized respectively;
(3) with each the component mix homogeneously among the prescription A, general ball makes 2~4mm piller, drying;
(4), process granule or add Mel and process honeyed pill with each the component mix homogeneously among the prescription B.
Further, cross 80 mesh sieves in the said step (2) among prescription A and the prescription B behind all the other each component pulverize separately.
For the material that makes extraction is an active substance, said extract obtains through following steps:
The material that (1) will extract is removed impurity;
(2) material that will remove impurity carries out pulverization process;
(3) ratio in 1Kg material and 10L water is put in it in extraction pot, refluxes 20~30 minutes, obtains extracting solution;
(4), concentrate this extracting solution with extracting solution suction concentration tank;
(5) the spray-dried extract that promptly makes of extracting solution after said the concentrating.
The present invention has the following advantages and beneficial effect:
1, the present invention is through being used of prescription A and prescription B, not only can integrally-regulated gastrointestinal function, and also the treatment back is difficult for repeatedly, side reaction is few;
2, the present invention is the various methods that a kind of high efficiency extraction effective ingredient is provided, and has not only kept drug effect greatly, and has improved the extraction content of effective ingredient;
3, average price of the present invention is cheap relatively, is suitable for promoting.
The specific embodiment
Constipation patient is seen with simulataneous insufficiency and excessive person more, or owing to sitting, lying on bed for a long time consumption gas, is promoted weak and constipation; Or plain body is cloudy loses or weakness of the spleen and stomach, the fortuneization imbalance of water Tianjin, and the body fluid acrinia causes the intestinal mistake to be moistened, and weary water is sailed a boat and is caused in the waste matter and stop.So mostly deficiency in origin is the deficiency of vital energy, the deficiency of YIN, mostly mark is the intestinal stagnation of QI in fact.Treatment when with the QI invigorating relaxing the bowels with lubricant drugs for wanting, hold concurrently with the circulation of qi promoting intestinal stasis relieving, the QI invigorating relaxing the bowels with lubricant drugs is a key of recovering the gastrointestinal conduction function, row stagnates, and to open secret be the effective means of improving gastrointestinal function.Therefore, the present invention is the basis with above-mentioned theory of Chinese medical science, studies, and has carried out clinical experiment, and effect is rather good.
Be example below with the clinical experiment, the present invention is done to specify further, but embodiment of the present invention be not limited thereto.
Embodiment 1
At first, obtain the extract of various materials, extraction step is following:
The material that (1) will extract is removed impurity; Like the radix linderae extract, the medicinal part of radix linderae is taken out;
(2) material that will remove impurity carries out pulverization process; Promptly handle, it is crushed to 20 orders through pulverizer;
(3) ratio in 1Kg radix linderae and 10L water is put in it in extraction pot, refluxes 20~30 minutes, obtains extracting solution; Extracting temperature is 100 ℃;
(4) with extracting solution suction concentration tank, concentrate this extracting solution, promptly adopt the conventional method for concentration of the field of Chinese medicines under 90 ℃ of left and right sides conditions, to concentrate this extracting solution;
(5) the spray-dried radix linderae extract that promptly makes of extracting solution after said the concentrating.
Various extracts all obtain through above method among prescription A and the prescription B.
Secondly, each component of non-extract among prescription A and the prescription B is pulverized respectively; Be crushed to its fineness smaller or equal to 80 orders.Can when pulverizing, cross 80 purposes sieve here, just sifted out smaller or equal to 80 purpose components, all the other compositions are proceeded to pulverize.Need pulverized component that Radix Notoginseng powder, Radix Aconiti Lateralis Preparata, Oletum Trogopterori, Margarita powder, artificial Calculus Bovis, Borneolum Syntheticum, Ganoderma spore powder, oligochitosan and vitamin C among the prescription A, Fructus Mume among the prescription B and oligochitosan are arranged in the present embodiment.
Moreover; With 2 parts of the radix linderae extracts among the prescription A, 2 parts of Radix Salviae Miltiorrhizae extracts, 2 parts of Rhizoma Corydalis extracts, 2 parts of Radix Notoginseng powder, 2 parts of Radix Clematidis extracts, 2 parts of Radix Aconiti Lateralis Preparatas, 2 parts of Cortex Eucommiae extract, 2 parts of Radix Achyranthis Bidentatae extracts, 2 parts of Radix Bupleuri extracts, 2 parts of Rhizoma Chuanxiong extracts, 2 parts of Oletum Trogopteroris, 2 parts of Margarita powder, 2 parts of artificial Calculus Boviss, 1 part of Borneolum Syntheticum, 16 parts of Ganoderma spore powders, 8 parts of oligochitosans, 2 parts of Radix Sophorae Flavescentis extracts, 1 part of Semen Vitis viniferae extract, 2 parts of resveratrol extracts, 6 parts of Radix Ginseng extracts, 6 parts of Herba Epimedii extracts, 10 parts of Herba Lysimachiae extracts, 20 parts of Herba Hedyotidis Diffusae extracts, 10 parts of Herba Scutellariae Barbatae extracts and 2 parts of mix homogeneously of vitamin C, general ball makes the piller that diameter is 3mm.
At last; With 20 parts of the Fructus Crataegi extracts among the prescription B, 10 parts of Radix Aucklandiae extracts, 12 parts of Radix Astragali extracts, 2 parts of Radix Salviae Miltiorrhizae extracts, 2 parts of Radix Codonopsis extracts, 6 parts of Ramulus euonymi extracts, 4 parts of Radix Clematidis extracts, 6 parts of Fructus Jujubae extracts, 2 parts of Radix Achyranthis Bidentatae extracts, 4 parts of Rhizoma Atractylodis Macrocephalae extracts, 4 parts of Rhizoma Smilacis Glabrae extracts, 2 parts of Cortex Cinnamomi extracts, 2 parts of Radix Angelicae Sinensis extracts, 2 parts of Rhizoma Chuanxiong extracts, 3 parts of Radix Paeoniae Rubra extracts, 2 parts in Semen Persicae extract, 2 parts of Flos Carthami extracts, 2 parts of Radix Polygoni Multiflori extracts, 6 parts of Caulis Polygoni Multiflori extracts, 4 parts of Cortex Eucommiae extract, 2 parts of Bulbus Fritillariae Cirrhosae extracts, 4 parts of radix linderae extracts, 2 parts of Radix Rehmanniae extracts, 6 parts of Fructus Ligustri Lucidi extracts, 6 parts of Fructus Hordei Germinatus extracts, 4 parts of Fructus Schisandrae Chinensis extrats, 6 parts of Fructus Lycii extracts, 3 parts of Fructus Evodiae extracts, 2 parts of Fructus Mume, 2 parts of Rhizoma Anemarrhenae extracts, 2 parts of Radix Asparagi extracts, 2 parts of Radix Ophiopogonis extracts, 2 parts of Radix Morindae Officinalis extracts and 2 parts of mix homogeneously of oligochitosan, through granulations, drying, granulate, be packaged to be every granule that wraps 3g; Perhaps, add Mel and process the 3g honeyed pill.What present embodiment adopted is to process the 3g honeyed pill.
Embodiment 2
Present embodiment only is that with the difference of embodiment 1 weight portion of prescription A and prescription B is different.
Prescription A: 2 parts of radix linderae extracts; 3 parts of Radix Salviae Miltiorrhizae extracts; 4 parts of Rhizoma Corydalis extracts; 2 parts of Radix Notoginseng powder; 1 part of Radix Clematidis extract; 4 parts of Radix Aconiti Lateralis Preparatas; 3 parts of Cortex Eucommiae extract; 3 parts of Radix Achyranthis Bidentatae extracts; 1 part of Radix Bupleuri extract; 3 parts of Rhizoma Chuanxiong extracts; 1 part of Oletum Trogopterori; 2 parts of Margarita powder; 2 parts of artificial Calculus Boviss; 2 parts of Borneolum Syntheticums; 18 parts of Ganoderma spore powders; 10 parts of oligochitosans; 3 parts of Radix Sophorae Flavescentis extracts; 3 parts of Semen Vitis viniferae extracts; 1 part of resveratrol extract; 7 parts of Radix Ginseng extracts; 4 parts of Herba Epimedii extracts; 12 parts of Herba Lysimachiae extracts; 19 parts of Herba Hedyotidis Diffusae extracts; 11 parts of Herba Scutellariae Barbatae extracts; 3 parts of vitamin Cs
Prescription B: 13 parts of Fructus Crataegi extracts; 7 parts of Radix Aucklandiae extracts; 14 parts of Radix Astragali extracts; 3 parts of Radix Salviae Miltiorrhizae extracts; 1 part of Radix Codonopsis extract; 5 parts of Ramulus euonymi extracts; 5 parts of Radix Clematidis extracts; 7 parts of Fructus Jujubae extracts; 2 parts of Radix Achyranthis Bidentatae extracts; 3 parts of Rhizoma Atractylodis Macrocephalae extracts; 5 parts of Rhizoma Smilacis Glabrae extracts; 4 parts of Cortex Cinnamomi extracts; 4 parts of Radix Angelicae Sinensis extracts; 3 parts of Rhizoma Chuanxiong extracts; 3 parts of Radix Paeoniae Rubra extracts; 1 part in Semen Persicae extract; 2 parts of Flos Carthami extracts; 4 parts of Radix Polygoni Multiflori extracts; 7 parts of Caulis Polygoni Multiflori extracts; 5 parts of Cortex Eucommiae extract; 3 parts of Bulbus Fritillariae Cirrhosae extracts; 5 parts of radix linderae extracts; 3 parts of Radix Rehmanniae extracts; 7 parts of Fructus Ligustri Lucidi extracts; 7 parts of Fructus Hordei Germinatus extracts; 5 parts of Fructus Schisandrae Chinensis extrats; 7 parts of Fructus Lycii extracts; 3 parts of Fructus Evodiae extracts; 3 parts of Fructus Mume; 3 parts of Rhizoma Anemarrhenae extracts; 1 part of Radix Asparagi extract; 2 parts of Radix Ophiopogonis extracts; 2 parts of Radix Morindae Officinalis extracts; 3 parts of oligochitosans.
Embodiment 3
Present embodiment only is that with the difference of embodiment 1 weight portion of prescription A and prescription B is different.
Prescription A: 3 parts of radix linderae extracts; 3 parts of Radix Salviae Miltiorrhizae extracts; 2 parts of Rhizoma Corydalis extracts; 3 parts of Radix Notoginseng powder; 4 parts of Radix Clematidis extracts; 3 parts of Radix Aconiti Lateralis Preparatas; 2 parts of Cortex Eucommiae extract; 2 parts of Radix Achyranthis Bidentatae extracts; 4 parts of Radix Bupleuri extracts; 3 parts of Rhizoma Chuanxiong extracts; 1 part of Oletum Trogopterori; 1 part of Margarita powder; 3 parts of artificial Calculus Boviss; 3 parts of Borneolum Syntheticums; 10 parts of Ganoderma spore powders; 4 parts of oligochitosans; 4 parts of Radix Sophorae Flavescentis extracts; 3 parts of Semen Vitis viniferae extracts; 4 parts of resveratrol extracts; 5 parts of Radix Ginseng extracts; 5 parts of Herba Epimedii extracts; 7 parts of Herba Lysimachiae extracts; 25 parts of Herba Hedyotidis Diffusae extracts; 13 parts of Herba Scutellariae Barbatae extracts; 6 parts of vitamin Cs
Prescription B: 24 parts of Fructus Crataegi extracts; 13 parts of Radix Aucklandiae extracts; 14 parts of Radix Astragali extracts; 3 parts of Radix Salviae Miltiorrhizae extracts; 1 part of Radix Codonopsis extract; 4 parts of Ramulus euonymi extracts; 2 parts of Radix Clematidis extracts; 9 parts of Fructus Jujubae extracts; 3 parts of Radix Achyranthis Bidentatae extracts; 2 parts of Rhizoma Atractylodis Macrocephalae extracts; 3 parts of Rhizoma Smilacis Glabrae extracts; 4 parts of Cortex Cinnamomi extracts; 4 parts of Radix Angelicae Sinensis extracts; 2 parts of Rhizoma Chuanxiong extracts; 3 parts of Radix Paeoniae Rubra extracts; 3 parts in Semen Persicae extract; 3 parts of Flos Carthami extracts; 2 parts of Radix Polygoni Multiflori extracts; 5 parts of Caulis Polygoni Multiflori extracts; 5 parts of Cortex Eucommiae extract; 3 parts of Bulbus Fritillariae Cirrhosae extracts; 2 parts of radix linderae extracts; 1 part of Radix Rehmanniae extract; 3 parts of Fructus Ligustri Lucidi extracts; 4 parts of Fructus Hordei Germinatus extracts; 5 parts of Fructus Schisandrae Chinensis extrats; 6 parts of Fructus Lycii extracts; 5 parts of Fructus Evodiae extracts; 3 parts of Fructus Mume; 2 parts of Rhizoma Anemarrhenae extracts; 1 part of Radix Asparagi extract; 2 parts of Radix Ophiopogonis extracts; 1 part of Radix Morindae Officinalis extract; 2 parts of oligochitosans.
Instructions of taking:
Get 1~3 of the granule that makes according to prescription B 1~3 bag or big honeyed pills, use the eliminating cold for resuscitation broken off by water flush; Get the piller 5~10g that makes according to prescription A again, B is used with prescription, every day three times, takes more than 3 months.
Detection method is following:
Select 98 constipation patients, and let it take the product that makes according to the present invention.Taking dose is: prescription A5~10g, 1~3 of the honeyed pill that prescription B makes.1~3 of the honeyed pill that at first prescription B is made is used the eliminating cold for resuscitation broken off by water flush, cooks tea and drinks, and the while is used with piller 5~10g that prescription A makes, and every day three times, takes 3 months.Concrete consumption when taking is confirmed according to patient's situation.
Its testing result is: obvious effective rate reaches 89%, and total effective rate reaches 97%.
Testing result according to above shows: the effect that the present invention treats constipation is remarkable, is higher than the effect of existing treatment constipation product far away.And through detecting: the gastrointestinal function that the medicine that the present invention prepares can integrally-regulated patient therapeutical effect is played in constipation, and the treatment back is difficult for repeatedly, side reaction is few.

Claims (6)

1. the two prescription medicines that are used to treat constipation is characterized in that, said medicine is made up of the prescription A of 5~10 weight portions and the prescription B of 3~9 weight portions,
Said prescription A is by the radix linderae extract; Radix Salviae Miltiorrhizae extract; The Rhizoma Corydalis extract; Radix Notoginseng powder; Radix Clematidis extract; Radix Aconiti Lateralis Preparata; Cortex Eucommiae extract; Radix Achyranthis Bidentatae extract; Radix Bupleuri extract; Rhizoma Chuanxiong extract; Oletum Trogopterori; Margarita powder; The artificial Calculus Bovis; Borneolum Syntheticum; Ganoderma spore powder; Oligochitosan; Radix Sophorae Flavescentis extract; Semen Vitis viniferae extract; Resveratrol extract; Radix Ginseng extract; Herba Epimedii extract; Herba Lysimachiae extract; Herba Hedyotidis Diffusae extract; Herba Scutellariae Barbatae extract and vitamin C are formed
Said prescription B is by the Fructus Crataegi extract; Radix Aucklandiae extract; Radix Astragali extract; Radix Salviae Miltiorrhizae extract; Radix Codonopsis extract; Ramulus euonymi extract; Radix Clematidis extract; Fructus Jujubae extract; Radix Achyranthis Bidentatae extract; Rhizoma Atractylodis Macrocephalae extract; Rhizoma Smilacis Glabrae extract; Cortex Cinnamomi extract; Radix Angelicae Sinensis extract; Rhizoma Chuanxiong extract; The Radix Paeoniae Rubra extract; Semen Persicae extract; Flos Carthami extract; Radix Polygoni Multiflori extract; The Caulis Polygoni Multiflori extract; Cortex Eucommiae extract; The Bulbus Fritillariae Cirrhosae extract; The radix linderae extract; Radix Rehmanniae extract; Fructus Ligustri Lucidi extract; The Fructus Hordei Germinatus extract; Fructus Schisandrae Chinensis extrat; Fructus Lycii extract; Fructus Evodiae extract; Fructus Mume; Rhizoma Anemarrhenae extract; The Radix Asparagi extract; Radix Ophiopogonis extract; Radix Morindae Officinalis extract and oligochitosan are formed.
2. a kind of two prescription medicines that are used to treat constipation according to claim 1 is characterized in that said prescription A and prescription B are made up of the component of following weight portion,
Prescription A: 1~4 part of radix linderae extract; 1~4 part of Radix Salviae Miltiorrhizae extract; 1~4 part of Rhizoma Corydalis extract; 1~4 part of Radix Notoginseng powder; 1~4 part of Radix Clematidis extract; 1~4 part of Radix Aconiti Lateralis Preparata; 1~4 part of Cortex Eucommiae extract; 1~4 part of Radix Achyranthis Bidentatae extract; 1~4 part of Radix Bupleuri extract; 1~4 part of Rhizoma Chuanxiong extract; 1~4 part of Oletum Trogopterori; 1~4 part of Margarita powder; 1~4 part of artificial Calculus Bovis; 1~3 part of Borneolum Syntheticum; 10~25 parts of Ganoderma spore powders; 4~12 parts of oligochitosans; 1~4 part of Radix Sophorae Flavescentis extract; 1~3 part of Semen Vitis viniferae extract; 1~4 part of resveratrol extract; 3~9 parts of Radix Ginseng extracts; 3~9 parts of Herba Epimedii extracts; 5~15 parts of Herba Lysimachiae extracts; 10~30 parts of Herba Hedyotidis Diffusae extracts; 5~15 parts of Herba Scutellariae Barbatae extracts; 1~4 part of vitamin C
Prescription B: 10~30 parts of Fructus Crataegi extracts; 5~15 parts of Radix Aucklandiae extracts; 6~18 parts of Radix Astragali extracts; 1~4 part of Radix Salviae Miltiorrhizae extract; 1~4 part of Radix Codonopsis extract; 3~9 parts of Ramulus euonymi extracts; 2~6 parts of Radix Clematidis extracts; 3~9 parts of Fructus Jujubae extracts; 1~4 part of Radix Achyranthis Bidentatae extract; 2~6 parts of Rhizoma Atractylodis Macrocephalae extracts; 2~6 parts of Rhizoma Smilacis Glabrae extracts; 1~4 part of Cortex Cinnamomi extract; 1~4 part of Radix Angelicae Sinensis extract; 1~4 part of Rhizoma Chuanxiong extract; 2~5 parts of Radix Paeoniae Rubra extracts; 1~4 part in Semen Persicae extract; 1~4 part of Flos Carthami extract; 1~4 part of Radix Polygoni Multiflori extract; 3~9 parts of Caulis Polygoni Multiflori extracts; 2~6 parts of Cortex Eucommiae extract; 1~4 part of Bulbus Fritillariae Cirrhosae extract; 2~6 parts of radix linderae extracts; 1~4 part of Radix Rehmanniae extract; 3~9 parts of Fructus Ligustri Lucidi extracts; 3~9 parts of Fructus Hordei Germinatus extracts; 2~6 parts of Fructus Schisandrae Chinensis extrats; 3~9 parts of Fructus Lycii extracts; 2~5 parts of Fructus Evodiae extracts; 1~4 part of Fructus Mume; 1~4 part of Rhizoma Anemarrhenae extract; 1~4 part of Radix Asparagi extract; 1~4 part of Radix Ophiopogonis extract; 1~4 part of Radix Morindae Officinalis extract; 1~4 part of oligochitosan.
3. a kind of two prescription medicines that are used to treat constipation according to claim 2 is characterized in that said prescription A and prescription B are made up of the component of following weight portion,
Prescription A: 2 parts of radix linderae extracts; 2 parts of Radix Salviae Miltiorrhizae extracts; 2 parts of Rhizoma Corydalis extracts; 2 parts of Radix Notoginseng powder; 2 parts of Radix Clematidis extracts; 2 parts of Radix Aconiti Lateralis Preparatas; 2 parts of Cortex Eucommiae extract; 2 parts of Radix Achyranthis Bidentatae extracts; 2 parts of Radix Bupleuri extracts; 2 parts of Rhizoma Chuanxiong extracts; 2 parts of Oletum Trogopteroris; 2 parts of Margarita powder; 2 parts of artificial Calculus Boviss; 1 part of Borneolum Syntheticum; 16 parts of Ganoderma spore powders; 8 parts of oligochitosans; 2 parts of Radix Sophorae Flavescentis extracts; 1 part of Semen Vitis viniferae extract; 2 parts of resveratrol extracts; 6 parts of Radix Ginseng extracts; 6 parts of Herba Epimedii extracts; 10 parts of Herba Lysimachiae extracts; 20 parts of Herba Hedyotidis Diffusae extracts; 10 parts of Herba Scutellariae Barbatae extracts; 2 parts of vitamin Cs
Prescription B: 20 parts of Fructus Crataegi extracts; 10 parts of Radix Aucklandiae extracts; 12 parts of Radix Astragali extracts; 2 parts of Radix Salviae Miltiorrhizae extracts; 2 parts of Radix Codonopsis extracts; 6 parts of Ramulus euonymi extracts; 4 parts of Radix Clematidis extracts; 6 parts of Fructus Jujubae extracts; 2 parts of Radix Achyranthis Bidentatae extracts; 4 parts of Rhizoma Atractylodis Macrocephalae extracts; 4 parts of Rhizoma Smilacis Glabrae extracts; 2 parts of Cortex Cinnamomi extracts; 2 parts of Radix Angelicae Sinensis extracts; 2 parts of Rhizoma Chuanxiong extracts; 3 parts of Radix Paeoniae Rubra extracts; 2 parts in Semen Persicae extract; 2 parts of Flos Carthami extracts; 2 parts of Radix Polygoni Multiflori extracts; 6 parts of Caulis Polygoni Multiflori extracts; 4 parts of Cortex Eucommiae extract; 2 parts of Bulbus Fritillariae Cirrhosae extracts; 4 parts of radix linderae extracts; 2 parts of Radix Rehmanniae extracts; 6 parts of Fructus Ligustri Lucidi extracts; 6 parts of Fructus Hordei Germinatus extracts; 4 parts of Fructus Schisandrae Chinensis extrats; 6 parts of Fructus Lycii extracts; 3 parts of Fructus Evodiae extracts; 2 parts of Fructus Mume; 2 parts of Rhizoma Anemarrhenae extracts; 2 parts of Radix Asparagi extracts; 2 parts of Radix Ophiopogonis extracts; 2 parts of Radix Morindae Officinalis extracts; 2 parts of oligochitosans.
4. being used to described in the claim 1~3 treated the method for preparing of two prescription medicines of constipation, it is characterized in that, mainly is made up of following steps:
(1) prepares various extracts among prescription A and the prescription B;
(2) all the other each components among prescription A and the prescription B are pulverized respectively;
(3) with each the component mix homogeneously among the prescription A, general ball makes 2~4mm piller, drying;
(4) with each the component mix homogeneously among the prescription B, process granule, or adding Mel is processed honeyed pill.
5. the method for preparing that is used to treat two prescription medicines of constipation according to claim 4 is characterized in that, mistake 80 mesh sieves behind all the other each component pulverize separately among prescription A and the prescription B in the said step (2).
6. according to claim 4 or the 5 described method for preparinies that are used to treat two prescription medicines of constipation, it is characterized in that said extract obtains through following steps:
The material that (1) will extract is removed impurity;
(2) material that will remove impurity carries out pulverization process;
(3) ratio in 1Kg material and 10L water is put in it in extraction pot, refluxes 20~30 minutes, obtains extracting solution;
(4), concentrate this extracting solution with extracting solution suction concentration tank;
(5) the spray-dried extract that promptly makes of extracting solution after said the concentrating.
CN201110441847XA 2011-12-27 2011-12-27 Double-formula medicine used for treating constipation, and preparation method thereof Pending CN102423441A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102908497A (en) * 2012-10-31 2013-02-06 陶鸿飞 Medicament for treating atonic constipation
CN103142714A (en) * 2013-02-23 2013-06-12 上海浦东高星生物技术研究所 Electuary for treating senile constipation
CN114432420A (en) * 2022-04-08 2022-05-06 深圳德荫堂生物科技有限公司 Biological agent convenient for old people to expel toxin and defecate and production method thereof

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102908497A (en) * 2012-10-31 2013-02-06 陶鸿飞 Medicament for treating atonic constipation
CN103142714A (en) * 2013-02-23 2013-06-12 上海浦东高星生物技术研究所 Electuary for treating senile constipation
CN114432420A (en) * 2022-04-08 2022-05-06 深圳德荫堂生物科技有限公司 Biological agent convenient for old people to expel toxin and defecate and production method thereof

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Application publication date: 20120425