CN1279946C

CN1279946C - Medicinal wine and its producing method

Info

Publication number: CN1279946C
Application number: CNB200410068942XA
Authority: CN
Inventors: 张国强
Original assignee: Individual
Current assignee: Individual
Priority date: 2004-07-14
Filing date: 2004-07-14
Publication date: 2006-10-18
Anticipated expiration: 2024-07-14
Also published as: CN1586544A

Abstract

The present invention discloses a medicinal wine and a manufacture method, which relates to a medicine wine. After boiling, lifting, enzymolysis, concentration, turn dissolving action, ethanol recycling and flavoring agents and supplementary material addition are carried out on 65 Chinese medicinal materials, such as antlers, cordyceps, penis cervi, polygonatum, ginseng, saffron, etc., and then medicine of various preparations is manufactured. The medicinal wine of the present invention has the advantages that waste in blood can be cleared, and three high-fat indexes can reduced; the immune functions of human bodies are raised, tumor lumps are eliminated or reduced, the endocrine functions of human bodies are adjusted, the climacteric of women is delayed, and the secretory volume of tryptose is stimulated; the incidence rate of diabetes is lowered, the major blood circulation and microcirculation are improved, and pigment deposition is rapidly eliminated; the medicinal wine has obvious curative effects on cerebral apoplexy and hemiplegia, the oxygen carrying capability of cardiac muscles is raised, and the blood flow is changed; the blood viscosity is lowered, the weak conditions of neural systems are improved, the sleep quality is improved, and the medicinal wine has good curative effects on epilepsy patients; the medicinal wine also has obvious curative effects on various disease symptoms, such as gastrointestinal dysfunction, rheumatism, rheumatoid, etc., and can heal diseases.

Description

A kind of medicated wine and manufacture method thereof

Technical field

The present invention relates to a kind of medicated wine, the disease of the harm humans healthy life that obstacles such as the common blood of human body blood circulation of the treatment under particularly instructing with traditional Chinese medicine theory, immune system, hormonal system, nervous system cause.

Background technology

Along with industrialized high speed development, people's life is improved greatly, material progress unprecedentedly is improved, but follow industrialized development and people excessively to ask for to natural, environmental pollution day by day, bad in addition living habit and life, the fast pace of work, make human physical and mental health run into new threat again and again, modern civilization case such as diabetes, cardiovascular and cerebrovascular disease, be accompanied by bad life style (as eating and drinking too much at one meal, the overnutrition that the absorption Animal fat too much causes etc.) become worse greatly, bring great body and mind misery to the patient, also cause great financial burden to society, the inventor has developed a kind of medicated wine agent in conjunction with for many years drug research and clinical empirical summary, can play above-mentioned various symptoms and alleviate and therapeutical effect.Through 200 routine clinical researches, medicated wine of the present invention.From then on patient's " three-hypers " blood vessels symptom of approximate 100% disappears, rheumatoid patient's symptom of 96% is eliminated, 92% tumor patient lump dwindles more than 50%, approximate 100% old syndrome patient, climacteric syndrome patient, senile plaque, pigmentation after taking medicated wine of the present invention, symptoms such as menoxenia all improve significantly or recover normal, above data declaration, a kind of medicated wine has tangible curative effect in many common diseases of the current serious harm human health of treatment.

Summary of the invention

The objective of the invention is according to traditional Chinese medicine rationale,, the medical material in the prescription is made the medicated wine with basic therapeutical effect to diseases such as cardiovascular and cerebrovascular disease, endocrinopathy, immune diseases in conjunction with clinical practice.

For achieving the above object, the present invention takes following scheme to realize: pulverize the animal drugs material according to the proportioning of animal drug in the prescription (1), places retort, adds entry and specific protease (as carase, the blue or green enzyme of Fructus Citri tangerinae etc.).In insulation below 60 ℃, enzymolysis is complete until enzymolysis, regulates pH to 7.0 then, and is standby.(2) other vegetable drug in the prescription places after crushed to boil and carries jar, adds 8 times of water, and 100 ℃ are boiled secondary under normal pressure, and each 2 hours, the waste collecting decoction.After the merging of the leach cooking liquid in the enzymolysis solution in above-mentioned (1) and (2), be concentrated into proportion 1.35 (50 ℃) back and in concentrating, add 4 times of amount 95% ethanol, in 0 ℃ of-4 ℃ of following cold preservation filtration once more in 48 hours.Reclaim the ethanol in the solution, water adjustment solution concentration to the proportion 1.05 (30 ℃) that adds after handling promptly gets oleo stock.

Technology contents of the present invention is as follows:

One, Chu Fang feature and proportioning thereof (weight ratio)

2 of Penis et testis cervi, Cornu Cervi Pantotrichum 10g, Radix Trichosanthis 50g, 2 of Hippocampus, 2 of Solenognathus, Rhizoma Polygonati Odorati 100g, Rhizoma Cibotii 100g, Herba Cynomorii 200g, Fructus Lycii 150g, Stigma Croci 60g gives birth to Radix Rehmanniae Preparata, each 120g of the Radix Polygoni Multiflori, Semen sojae atricolor 200g, Semen Sesami Nigrum 15g, Concretio Silicea Bambusae 50g, Semen Juglandis 30g, Radix Bupleuri 100g, Rhizoma Gastrodiae 100g, Radix Et Caulis Acanthopanacis Senticosi 100g, Semen Ziziphi Spinosae 30g, Herba Potentillae Discoloris 50g, Herba Lycopodii 50g, Semen Plantaginis 50g, Semen Cassiae 50g, Semen Cuscutae 50g, Semen Celosiae 50g, FIOS ERIOCAULI 50g, Radix Paeoniae Alba 50g, Herba Saussureae Involueratae 10g, Radix Ginseng 50g, Radix Codonopsis 50g, Radix Adenophorae (Radix Glehniae) 50g, Caulis Spatholobi 120g, Radix Notoginseng 100g, Ramulus Uncariae Cum Uncis 50g, Radix Salviae Miltiorrhizae 100g, Radix Morindae Officinalis 200g, Ganoderma 100g, Fructus Ligustri Lucidi 50g, Radix Puerariae 50g, Cordyceps 20g, Fructus Schisandrae Chinensis 50g, Radix Rhodiolae 200g, mountain Yu meat (Fructus Corni) 50g, Cortex Eucommiae 50g, Rhizoma Chuanxiong 200g, Radix Glycyrrhizae 100g, Radix Scutellariae 100g, Pheretima 50g, Semen Euryales 50g, Herba Cistanches 100g, Fructus Rosae Laevigatae 50g, Radix Panacis Quinquefolii 50g, Rhizoma Dioscoreae 100g, 2 of Geckos, 1 of Scolopendra, 2 of Herba Orobanchess, Rhizoma Atractylodis 50g, black Radix Aconiti Lateralis Preparata 50g, Radix Bupleuri 200g, Radix Ginseng Rubra 150g, Carapax et Plastrum Testudinis 50g, Radix Angelicae Sinensis 100g, Radix Paeoniae Alba 50g.

Two, manufacture method:

1. the making of oleo stock:

A, select materials: select for use the kind of state-promulgated pharmacopoeia regulation to weigh by formula proportion and requirement ratio.

B, enzymolysis: animal drug is pulverized, placed retort, normal pressure adds 3 times of water gagings below 60 ℃, and enzyme-added, insulation is complete until the medical material enzymolysis, standby.

C, boil and carry: after vegetable drug or decoction pieces are pulverized, add 8 times of water gagings in the jar, under 100 ℃ of normal pressures, boil and carry secondary in boiling to carry, each 2 hours, merging filtrate, standby.

D, concentrate, the enzymolysis of B and C and leach cooking liquid merged after, be concentrated into proportion 1.35 (50 ℃).

E, precipitate with ethanol, in concentrating, add 4 times of amount 95% ethanol and add and stir back decocting liquid and enzymolysis solution waste, 0 ℃ of-4 ℃ of following cold preservation 48 hours, filtration once more.

F, ethanol reclaim, and are that 1.05 (30 ℃) promptly get the medicine slurry with adjusting solution concentration to proportion behind the conventional method recovery ethanol.

2. the making of various pharmaceutically dosage forms:

A, medicated wine are converted the high quality liquor of selecting for use according to calculating, join the medicated wine that blends into 18 °-56 ° in the medicine slurry, are medicated wine of the present invention behind the packing gland.

B, oral liquid: in the medicine slurry, add flavoring agent and other adjuvant and bottling and be oral liquid of the present invention.

C, solid electuary: medicine slurry is dry, pulverize the back adds flavoring agent, sieves behind the mix homogeneously to be dried into fine particle and to be powder electuary of the present invention.

D, oral soft extract: in the medicine slurry, add flavoring agent, thickening agent and bottling and be oral soft extract of the present invention.

E, tablet: with the medicinal residues oven dry, pulverize, add the slurry that is used as medicine, add other adjuvant again, make tablet behind the mix homogeneously, be oral tablet of the present invention.

The specific embodiment

Embodiment:

1. raw material: medical material kind and proportioning (weight ratio) by prescription are pulverized animal drug and vegetable drug respectively, shelve stand-by respectively.

The medical material kind and the proportioning of prescription:

2. the making of former medicine slurry:

The vegetable drug that (1) will wash is pulverized the back and is added and boils jar, and add 8 times of amounts through the water of processing (precipitation, fine straining, softening, disinfection) under normal pressure 100 ℃ decocted 2 hours, inclining the same method of water that decocting liquid adds 8 times of amounts again and decocts.Incline and decocting liquid and mixes common 20 kilograms of decocting liquids, waste, stand-by with decocting liquid for the first time.

(2) animal drug in 1 is pulverized, placed retort, add, add proteinase-10 .5g, water is heated to 55 ℃, and constant temperature 48 hours is complete to the animal drug enzymolysis, adjust the solution pH value and be 7.0 stand-by through 20 kilograms in pretreated water.

(3) decocting liquid and the enzymolysis solution with above-mentioned (1) and (2) mixes, in concentration tank, concentrate proportion 1.35 (50 ℃), the heavy 5.5kg of concentrated solution, add 22 kilograms of 95% ethanol, agitation and filtration removes slag slightly, adjust solution proportion 1.05 ± 0.001 (30 ℃) with adding softening disinfectant water in the solution, be total to such an extent that former medicine is starched 4 kilograms.

(4) making of medicated wine: 4 kilograms in former medicine slurry.38 ° of high-quality Sorghum vulgare Pers. Wine 16kg, 0.001 milliliter of edible essence adds the water to 26 kilogram of softening sterilization processing behind the mix homogeneously, mix evenly once more, and the bottling gland promptly gets safe medicated wine.

Claims

1. a medicated wine is characterized in that, it is the medicated wine of being made by the raw medicinal material of following weight ratio: 2 of Penis et testis cervi, Cornu Cervi Pantotrichum 10g, Radix Trichosanthis 50g, 2 of Hippocampus, 2 of Solenognathus, Rhizoma Polygonati Odorati 100g, Rhizoma Cibotii 100g, Herba Cynomorii 200g, Fructus Lycii 150g, Stigma Croci 60g, give birth to Radix Rehmanniae Preparata, each 120g of the Radix Polygoni Multiflori, Semen sojae atricolor 200g, Semen Sesami Nigrum 15g, Concretio Silicea Bambusae 50g, Semen Juglandis 30g, Radix Bupleuri 100g, Rhizoma Gastrodiae 100g, Radix Et Caulis Acanthopanacis Senticosi 100g, Semen Ziziphi Spinosae 30g, Herba Potentillae Discoloris 50g, Herba Lycopodii 50g, Semen Plantaginis 50g, Semen Cassiae 50g, Semen Cuscutae 50g, Semen Celosiae 50g, FIOS ERIOCAULI 50g, Radix Paeoniae Alba 50g, Herba Saussureae Involueratae 10g, Radix Ginseng 50g, Radix Codonopsis 50g, Radix Adenophorae (Radix Glehniae) 50g, Caulis Spatholobi 120g, Radix Notoginseng 100g, Ramulus Uncariae Cum Uncis 50g, Radix Salviae Miltiorrhizae 100g, Radix Morindae Officinalis 200g, Ganoderma 100g, Fructus Ligustri Lucidi 50g, Radix Puerariae 50g, Cordyceps 20g, Fructus Schisandrae Chinensis 50g, Radix Rhodiolae 200g, Fructus Corni 50g, Cortex Eucommiae 50g, Rhizoma Chuanxiong 200g, Radix Glycyrrhizae 100g, Radix Scutellariae 100g, Pheretima 50g, Semen Euryales 50g, Herba Cistanches 100g, Fructus Rosae Laevigatae 50g, Radix Panacis Quinquefolii 50g, Rhizoma Dioscoreae 100g, 2 of Geckos, 1 of Scolopendra, 2 of Herba Orobanchess, Rhizoma Atractylodis 50g, black Radix Aconiti Lateralis Preparata 50g, Radix Bupleuri 200g, Radix Ginseng Rubra 150g, Carapax et Plastrum Testudinis 50g, Radix Angelicae Sinensis 100g, Radix Paeoniae Alba 50g.

2. medicated wine according to claim 1, wherein containing alcoholic acid amount volume ratio is 18-56%.

3. medicated wine according to claim 1 can be made and is selected from: any dosage form of oral liquid, solid electuary, oral soft extract or tablet.

4. the described medicated wine preparation method of claim 1, it comprises the steps:

(1) weighs according to the medical material kind and the weight ratio proportioning of claim 1, respectively animal drug and vegetable drug are pulverized, shelve stand-by respectively;

(2) vegetable drug after will pulverizing adds and boils jar, and add 8 times of amounts through precipitations, fine straining, softening, water that disinfection is handled, 100 ℃ decocted 2 hours under normal pressure, inclining decocting liquid and adds the same method of the water of 8 times of amounts again and decoct, and inclines to decocting liquid and mix common 20 kilograms of decocting liquids, waste, stand-by with decocting liquid for the first time;

(3) animal drug of pulverizing is placed retort, add, add the blue or green enzyme 0.5g of carase or Fructus Citri tangerinae, water is heated to 55 ℃, and constant temperature 48 hours is complete to the animal drug enzymolysis, adjust the solution pH value and be 7.0 stand-by through 20 kilograms in pretreated water;

The decocting liquid of above-mentioned (1) and the enzymolysis solution of (2) are mixed, carrying out cocnentration factor in concentration tank, to focus on 50 ℃ be 1.35, concentrated solution weighs 5.5 kilograms, add 22 kilograms of 95% ethanol, agitation and filtration removes slag slightly, with add in the solution softening disinfectant water adjust solution proportion in 30 ℃ be 1.05 ± 0.001, altogether 4 kilograms in former medicine slurry.