CN110420143A - A kind of condensation and preparation method thereof containing nine grades of rank in the feudal regimes perfume Flos Nelumbinis extract - Google Patents
A kind of condensation and preparation method thereof containing nine grades of rank in the feudal regimes perfume Flos Nelumbinis extract Download PDFInfo
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- CN110420143A CN110420143A CN201910803016.9A CN201910803016A CN110420143A CN 110420143 A CN110420143 A CN 110420143A CN 201910803016 A CN201910803016 A CN 201910803016A CN 110420143 A CN110420143 A CN 110420143A
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- extract
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- flos nelumbinis
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- 241000628997 Flos Species 0.000 title claims abstract description 50
- 238000009833 condensation Methods 0.000 title claims abstract description 36
- 230000005494 condensation Effects 0.000 title claims abstract description 36
- 238000002360 preparation method Methods 0.000 title claims abstract description 15
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 23
- 238000000605 extraction Methods 0.000 claims abstract description 19
- 241000282376 Panthera tigris Species 0.000 claims abstract description 13
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 9
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- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims abstract description 3
- 239000004475 Arginine Substances 0.000 claims abstract description 3
- DFPAKSUCGFBDDF-UHFFFAOYSA-N Nicotinamide Chemical compound NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 claims abstract description 3
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- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 claims abstract description 3
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- 229960003966 nicotinamide Drugs 0.000 claims abstract description 3
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- 235000010493 xanthan gum Nutrition 0.000 claims abstract description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 32
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- 239000000706 filtrate Substances 0.000 claims description 10
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- 240000002853 Nelumbo nucifera Species 0.000 claims description 7
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- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 description 14
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- ORJVQPIHKOARKV-UHFFFAOYSA-N Nuciferine Natural products C1C2=CC=CC=C2C2=C(OC)C(OC)=CC3=C2C1N(C)CC3 ORJVQPIHKOARKV-UHFFFAOYSA-N 0.000 description 1
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- ORJVQPIHKOARKV-OAHLLOKOSA-N nuciferine Chemical compound C1C2=CC=CC=C2C2=C(OC)C(OC)=CC3=C2[C@@H]1N(C)CC3 ORJVQPIHKOARKV-OAHLLOKOSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/62—Nymphaeaceae (Water-lily family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/79—Schisandraceae (Schisandra family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/18—Antioxidants, e.g. antiradicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Animal Behavior & Ethology (AREA)
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- Public Health (AREA)
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- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
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- Microbiology (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Birds (AREA)
- Cosmetics (AREA)
Abstract
The invention belongs to cosmetic fields, disclose a kind of condensation and preparation method thereof containing nine grades of rank in the feudal regimes perfume Flos Nelumbinis extract.The condensation mainly includes following components: glycerol, xanthan gum, water, carbomer, glycine betaine, niacinamide, arginine, dried tremella extract, carboxymethylchitosan, dendrobium candidum stem extraction, nine grades of rank in the feudal regimes perfume Flos Nelumbinis extract, Caulis Kadsurae Coccineae extract, 1,3-BDO, essence, solubilizer, preservative.The present invention is by water lily extract and black tiger berry extract compatible use; with " water lily extract " for monarch; " black tiger berry extract " is minister; validity of products and stability can be dramatically increased; and skin can be made to fully absorb and utilize the effective component in formula; long-time service can protect epidermal cell from the infringement of free radical, and then reach the effect of improving skin quality, skin care, whitening and moisturizing, crease-resistant light spot, calm antiallergic.
Description
Technical field
The invention belongs to cosmetic field, in particular to a kind of condensation containing nine grades of rank in the feudal regimes perfume Flos Nelumbinis extract and its preparation
Method.
Background technique
With the increasingly raising of people's living standard, requirement of the people to beauty is more and more, the functional requirement to skin care item
It is higher and higher.Traditional skin protection cosmetics mainly come skin care, cleaning skin and improves skin by its nutritional ingredient and water conservation ingredient
The soft and moist property of skin.But contains a large amount of synthetics in traditional skin-protection product raw material, certain skin-care effect is being provided, is being changed
While kind appearance, some inevitable injuries also are brought to skin.Therefore, people start to pursue without any toxicity and side effects
Natural skin care product are delayed senescence with reaching, are smoothed away wrinkles, and restore the effect of flexible lubricant nature.
Condensation, it is more thick and heavy for the more general toner of quality generally as translucent milky white color substance, but again than essence
Frivolous, the liquid gel quality of China, it is salubrious easily to absorb, do not cause any burden to skin.Condensation has conditioning skin and supply
The effect of cuticula moisture, the plant essence contained simultaneously and the mineral spring factor can persist to skin, improve water shortage line, adjust
Save skin water and oil balance, be four seasons spring, summer, autumn and winter must skin care item.But condensation at present on the market has a single function, effect
It is limited.
Summary of the invention
In order to overcome the shortcomings and deficiencies of the prior art described above, the primary purpose of the present invention is that providing one kind contains the nine grades of rank in the feudal regimes
The condensation of perfume Flos Nelumbinis extract；
Another object of the present invention is to provide the preparation method of the above-mentioned condensation containing nine grades of rank in the feudal regimes perfume Flos Nelumbinis extract.
The purpose of the present invention is realized by following proposal:
A kind of condensation containing nine grades of rank in the feudal regimes perfume Flos Nelumbinis extract comprising the component of following mass percent:
A1 component: glycerol 5%, xanthan gum 0.05%；
A2 component: water 62.87%；
A3 component: carbomer 0.2%；
B component: glycine betaine 0.5%, niacinamide 2%, water 5%；
C component: arginine 0.1%；
D component: dried tremella extract 1%, carboxymethylchitosan 0.2%, dendrobium candidum stem extraction 1%, the nine grades of rank in the feudal regimes
Perfume Flos Nelumbinis extract, Caulis Kadsurae Coccineae extract；The wherein mass percent of nine grades of rank in the feudal regimes perfume Flos Nelumbinis extract and Caulis Kadsurae Coccineae extract
The sum of be 10%；
E1 component: essence 0.02%, solubilizer 0.06%；
E2 component: water 10%；
F component: 1,3-BDO 1%, preservative 1%.
Preferably, in the condensation containing nine grades of rank in the feudal regimes perfume Flos Nelumbinis extract, the quality of nine grades of rank in the feudal regimes perfume Flos Nelumbinis extract
Score is 7%, and the mass percent of Caulis Kadsurae Coccineae extract is 3%；
Preferably, in the condensation containing nine grades of rank in the feudal regimes perfume Flos Nelumbinis extract, the quality of nine grades of rank in the feudal regimes perfume Flos Nelumbinis extract
Score is 5%, and the mass percent of Caulis Kadsurae Coccineae extract is 5%；
Preferably, in the condensation containing nine grades of rank in the feudal regimes perfume Flos Nelumbinis extract, the quality of nine grades of rank in the feudal regimes perfume Flos Nelumbinis extract
Score is 3%, and the mass percent of Caulis Kadsurae Coccineae extract is 7%；
The solubilizer is preferably 1,3 butylene glycol；The preservative be preferably PHL (decoyl Qiang Wosuan &1,2 oneself two
Chun &1,3 propylene glycol).
" CN201610693617.5- is a kind of with reference to Chinese patent disclosure for the extracting method of the dried tremella extract
Low molecular weight tremella polysaccharides and the preparation method and application thereof ".
The extracting method of the dendrobium candidum stem extraction refers to Chinese patent disclosure
" a kind of Ultra-low molecular weight Dendrobium officinale polysaccharide of CN201810743725.9- and its preparation and application ".
The nine grades of rank in the feudal regimes perfume Flos Nelumbinis extract is extracted to obtain by following methods:
(1) take fresh nine grades of rank in the feudal regimes perfume lotus flower, dry surface water after cleaning up, be added tissue mashing machine in homogenate at
Mucus shape adds water and stirs extraction into gained homogenate, then filters, and is by mass concentration is added after the concentration of gained filtrate
95% ethyl alcohol, mixes well, and filters after precipitation to be precipitated, collects precipitating；
(2) gained is precipitated and is decolourized with addition active carbon after 50~80 DEG C of hot water dissolvings, be then filtered to remove activity
Gained filtrate is concentrated charcoal, and the ethyl alcohol that mass concentration is 95% is added into concentrate, is centrifugated, goes after mixing well
Clear liquid collects precipitating, dry to get nine grades of rank in the feudal regimes Flos Nelumbinis extract.
In the extraction process of nine grades of rank in the feudal regimes perfume Flos Nelumbinis extract:
The water stirring 2h that 5~10 times of volumes are preferably added is added water and stirred described in step (1)；It, can sufficiently to extract
The filter residue for adding water and stirring and obtaining after filtering is repeated several times the operation added water and stirred；
The time of decoloration described in step (2) is 5~60min；The speed of centrifuge separation described in step (2) is
500~3000r/min；Drying described in step (2) is preferably dried in vacuo at 50~80 DEG C；
Step (1) concentration corresponding with the ethyl alcohol both preferably addition that addition mass concentration described in step (2) is 95%
The ethyl alcohol that the mass concentration of 5~10 times of volumes of liquid is 95%；Concentration described in step (1) and step (2) is referred both to 20~60
DEG C it is concentrated under reduced pressure into the 10~40% of original volume.
The Caulis Kadsurae Coccineae extract is extracted to obtain by following steps:
It is dried after black tiger is cleaned, grinds and cross 20~200 meshes, carry out refluxing extraction after 90% ethyl alcohol is added, so
After filter, by gained filtrate in 50 DEG C~85 DEG C vacuum drying to get Caulis Kadsurae Coccineae extract.
In the extraction process of the Caulis Kadsurae Coccineae extract, the drying preferably 40~60 DEG C dry 12~for 24 hours；
90% ethyl alcohol of the addition preferably presses solid-liquid ratio 1:5~15 and 90% ethyl alcohol is added；The time of the refluxing extraction is 1
~5h.
In the extraction process of the Caulis Kadsurae Coccineae extract, in order to sufficiently extract, filtered filter residue can be repeated several times
Then the operation of refluxing extraction and filtering merges gained filtrate, be dried in vacuo then at 50 DEG C~85 DEG C；Duplicate number is preferred
It is 1~5 time；
A kind of preparation method of the above-mentioned condensation containing nine grades of rank in the feudal regimes perfume Flos Nelumbinis extract, comprising the following steps:
(1) A1 component is uniformly mixed, A2 component is added and stirs evenly, adds A3 component and stirs evenly, 82 ± 5
DEG C heating, keep the temperature 3-5min, stirring be cooled to 43 ± 2 DEG C, for use；
(2) B component is added in the mixture obtained to step (1), stirs evenly, normal-temperature dissolution is stand-by；
(3) C component is added in the mixture obtained to step (2) to stir evenly, adds D component and stirs evenly, then plus
Enter the mixture of E1 component and E2 component, stirring at normal temperature is uniformly stand-by；
(4) F component is added in the mixture obtained to step (3) to stir evenly, is cooled to 30 ± 5 degree to system temperature,
It is stirred under vacuum；
(5) detection indices qualification discharging.
Mixing speed described in step (1)~(4) is preferably 400~600rpm；
Do not indicate that temperature refers both to carry out at room temperature in the present invention.
Nine grades of rank in the feudal regimes perfume lotus flower is a kind of large-scale water lily of raw perennial root flowering marsh plants.Its Hua Shuo great, the bright-coloured beauty of pattern, has
The nine big colour systems such as golden, yellow, purple, blue, red, tea, green, red, white, therefore named nine grades of rank in the feudal regimes perfume lotus.Plant rich in perfume lotus flower
Placental hormone, flavones, Nuciferine, Thick many candies, oligosaccharide and crude fibre etc..Studies have shown that nine grades of rank in the feudal regimes perfume Flos Nelumbinis extract is with good
Good moisture-keeping function, is excellent natural moisturizer.Secondly, also having, anti-oxidant, Shu Min is antipruritic, anti-inflammatory, anticancer and other effects.
Black tiger also known as kadsurae coccineae, the south the great Ye five tastes, being that Schisandraceae Kadsura is evergreen climbs up by holding on to liana.It is black old
Contain lignanoids and the ingredients such as triterpenes and monoterpenes, sesquiterpenoids, steroid, amino acid in brave berry extract.It is modern
Medical research shows that black tiger berry extract has the effects that anti-oxidant, antitumor, antiviral, anti-hepatic fibrosis.
The present invention compared with the existing technology, have the following advantages and the utility model has the advantages that
Product of the present invention has calm antiallergic effect well.Flavones can inhibit inflammation related substances in water lily extract,
Reducing vasopermeability prevents inflammation from spreading, while cell surface being protected not cause largely to remain because of a large amount of microbial reproductions
Inflammation caused by substance, while immune system can be enhanced, reduce the generation of inflammation.Lignin in black tiger berry extract can press down
The generation of NO processed, and then the degree of inflammation is reduced, avoid inflammation from reinforcing, while also there is antimicrobial stability and thermal stability.
Product of the present invention has good whitening anti-wrinkling effect.Polysaccharide in water lily extract is made with good moisturizing
With, it is excellent natural moisturizer, while also having the function of anti-oxidant, strengthen immunity and reducing blood lipid etc.；Flavones can be effective
Intracorporal oxygen radical is removed, activities of antioxidant enzymes is improved, while having synergistic effect with vitamin C, vitamin C can be made in people
It tends towards stability in body tissue.Black tiger berry extract vitamin C rich in, can promote the formation of collagen, makes skin
It is smooth, whitening, flexible, it prevents skin from occurring wrinkle aged, also has the function of anti-oxidant, anti-aging, fiber can be increased
Mother cell is to ascorbic absorption, thus the synthesis of stimulation collagen；Inhibit metalloproteinases (MMP-2 and MMP-9) living
Property, prevent the degradation of extracellular matrix components；Free radical is neutralized, there is good antioxygenic property；Slow down wrinkle depth, increases
Skin elasticity plays crease-resistant wrinkle resistant effect.
The present invention is by water lily extract and black tiger berry extract compatible use, with " water lily extract " for monarch, " black tiger
Berry extract " is minister, can dramatically increase validity of products and stability, and skin can be made to fully absorb and utilize having in formula
Ingredient is imitated, long-time service can protect epidermal cell from the infringement of free radical, and then reach improvement skin quality, skin care, beauty
The effect of white moisturizing, crease-resistant light spot, calm antiallergic.
Detailed description of the invention
Fig. 1 is volunteer before the condensation prepared using the embodiment of the present invention and using the photo figure now after 2 weeks.
Specific embodiment
Below with reference to embodiment and attached drawing, the present invention is described in further detail, but embodiments of the present invention are unlimited
In this.
Agents useful for same can routinely be bought unless otherwise specified from market in embodiment.
The dried tremella extract is with reference to a kind of Chinese patent disclosure " low molecular weight of CN201610693617.5-
The low molecular weight tremella polysaccharides that the method for embodiment 1 in tremella polysaccharides and the preparation method and application thereof " is prepared.
The dendrobium candidum stem extraction is that " CN201810743725.9- one kind is super with reference to Chinese patent disclosure
The Ultra-low molecular weight iron sheet that the method for embodiment 1 in low molecular weight Dendrobium officinale polysaccharide and its preparation and application " is prepared
Dendrobium polysaccharide.
Examples 1 to 3 and comparative example 1~3
The formula of Examples 1 to 3 and comparative example 1~3 is as shown in table 1 below, and wherein nine grades of rank in the feudal regimes perfume lotus flower extracts in embodiment 1
The parts by weight of object are 7 parts, and the parts by weight of Caulis Kadsurae Coccineae extract are 3 parts；The weight of nine grades of rank in the feudal regimes perfume Flos Nelumbinis extract in embodiment 2
Measuring number is 5 parts, and the parts by weight of Caulis Kadsurae Coccineae extract are 5 parts, remaining Ingredient Amount is consistent with embodiment 1；In embodiment 3
The parts by weight of nine grades of rank in the feudal regimes perfume Flos Nelumbinis extract are 3 parts, and the parts by weight of Caulis Kadsurae Coccineae extract are 7 parts, remaining Ingredient Amount is equal
It is consistent with embodiment 1；The parts by weight of nine grades of rank in the feudal regimes perfume Flos Nelumbinis extract are 0 part in comparative example 1, the parts by weight of Caulis Kadsurae Coccineae extract
Number is 10 parts, remaining Ingredient Amount is consistent with embodiment 1；The parts by weight of nine grades of rank in the feudal regimes perfume Flos Nelumbinis extract are in comparative example 2
10 parts, the parts by weight of Caulis Kadsurae Coccineae extract are 0 part, remaining Ingredient Amount is consistent with embodiment 1；The nine grades of rank in the feudal regimes is fragrant in comparative example 3
The parts by weight of water Flos Nelumbinis extract are 0 part, and the parts by weight of Caulis Kadsurae Coccineae extract are 0 part, remaining Ingredient Amount with implementation
Example 1 is consistent.
Nine grades of rank in the feudal regimes perfume Flos Nelumbinis extract in Examples 1 to 3 and comparative example 1~3 the preparation method comprises the following steps: taking the fresh nine grades of rank in the feudal regimes
Perfume lotus flower is cleaned up and is dried in 80 DEG C of baking ovens, and homogenate is at mucus shape in tissue mashing machine.7 times are added into homogenate
2h, filtering are extracted in the distilled water stirring of volume, and filter residue repeats extraction 2 times.Merging filtrate, 40 DEG C are concentrated under reduced pressure into original volume
25%.The ethyl alcohol that 3 times of volume mass concentration are 95% is added in concentrate, mixes well, is filtered after precipitation to be precipitated, collects
Precipitating, by sediment with after 50-80 DEG C of hot water dissolving plus active carbon decoloring 20min, being filtered to remove active carbon and by gained filtrate
40 DEG C are concentrated under reduced pressure into the 25% of original volume, and the ethyl alcohol that the mass concentration of 3 times of volumes is 95% is added in concentrate, sufficiently mixed
It is even, be centrifugated under the revolving speed of 1000r/min, supernatant collection gone to precipitate, and in 50 DEG C~85 DEG C vacuum drying to get.
The preparation method of black tiger (KADSURA COCCINEA) berry extract in Examples 1 to 3 and comparative example 1~3
Are as follows: black tiger is cleaned, after 50 DEG C of dry 18h cross 60 meshes, by solid-liquid ratio 1:10 addition 90% ethyl alcohol, refluxing extraction 3 times, often
Secondary 2h, extract filtering, merges 3 filtrates, and in 50 DEG C~85 DEG C vacuum drying to get.
The formula of the condensation prepared in 1 Examples 1 to 3 of table and comparative example 1~3
The preparation step of embodiment 1-3 and comparative example 1-3 are as follows:
Step 1: sequentially adding A1 component raw material and stir evenly, and A2 component raw material is added and stirs evenly, adds A3 component
Raw material stirs evenly, and 82 ± 5 DEG C of heating keep the temperature 3-5min, and stirring is cooled to 43 ± 2 DEG C, for use.
Step 2: B component raw material is added and stirs evenly, normal-temperature dissolution is stand-by.
Step 3: C component is added and stirs evenly, sequentially adds D component and stirs evenly, E component (E1 component premixed liquid is added
Mixed with E2 component), stirring at normal temperature is uniformly stand-by.
Step 4: F component prefabricated solution is added and stirs evenly.
Step 5: 30 ± 5 degree are cooled to system temperature, is stirred under vacuum.
Step 7: detection indices qualification discharging.
Wherein 400~the 600rpm of mixing speed.
Efficacy test:
Test crowd: call-up age 25-60 years old female volunteers 60, cardinal symptom are as follows: face has allergy red dot scabies
Itch and wrinkle is obvious.Volunteer is randomly divided into 6 groups, every group of 10 people.
Measure environment: test environment temperature (22 ± 1) DEG C, humidity (50 ± 5) % are averaged.
Application method: every group of volunteer be daily morning and evening after thorough clean skin, uniformly smears embodiment 1-3 and right in face respectively
The skin care item of ratio 1-3 preparation, recipient site is without using other any cosmetics in addition to given the test agent during test, continuously
It uses 2 weeks.
One, calm antiallergic effect assessment
Test method: questionnaire survey is carried out to test crowd.
Evaluation criteria: effective-itch is substantially reduced or disappears, and secondary skin lesion subsides substantially, has at itch skin and obviously change
It is kind；Effectively-itch mitigates, and secondary skin lesion makes moderate progress, and itch skin makes moderate progress；In vain-itch is without improvement, and secondary skin lesion is not
Mitigate, itch skin does not improve.
The calm antiallergic Contrast on effect of condensation prepared by 2 Examples 1 to 3 of table and comparative example 1~3
From Table 2, it can be seen that allergic phenomena all improves significantly after using skin care item of the present invention 2 weeks.It is real
It tests result and illustrates the transdermal absorption of condensation containing nine grades of rank in the feudal regimes perfume Flos Nelumbinis extract, effective component is made to be absorbed into flesh from skin surface
Skin skin corium improves skin quality, moisturizes the skin, solves the problems, such as that skin has allergy red dot itch, has good calmness
Antiallergic effect.
Two, whitening anti-wrinkling effect is tested and assessed
(1) white-skinned face function
Test method: face's skin is measured on the day before this product use and after continuous use 2 weeks respectively with skin pigment instrument
Skin melanin content.Measured value is higher, and melanin content is higher in skin.The average value of melanin reduced rate is higher, whitening effect
Fruit is more obvious.
Calculation formula: melanin reduced rate=(contained using 14 days melanin after preceding melanin content-continuous use in 1 day
Amount)/use preceding 1 day melanin content * 100%.
The melanin reduced rate of the average value of melanin reduced rate=every group and/10.
The white-skinned face function test data table of condensation prepared by 3 Examples 1 to 3 of table and comparative example 1~3
From table 3 it is observed that the condensation of the invention containing nine grades of rank in the feudal regimes perfume Flos Nelumbinis extract can effectively inhibit melanin
It generates, and effect is obvious.
(2) crease-resistant effect
Test method: questionnaire survey is carried out to test crowd.
Evaluation criteria: effective-skin smooth high resilience, wrinkle are obviously desalinated, and small microgroove disappears；Effectively-skin is more
Smooth, elasticity makes moderate progress, and small microgroove is obviously desalinated, but wrinkle still remains；In vain-small microgroove, wrinkle still remain, even
Has the tendency that intensification.
The anti-wrinkle effect comparison of condensation prepared by 4 Examples 1 to 3 of table and comparative example 1~3
From table 4, it can be seen that the condensation prepared by the present invention containing nine grades of rank in the feudal regimes perfume Flos Nelumbinis extract can significantly reduce microgroove,
Make dermatoglyph more expansion, delay skin aging.
One of volunteer (number 1902001E01) is chosen, contains the nine grades of rank in the feudal regimes what is prepared using the embodiment of the present invention 1
Behind condensation 2 weeks of Flos Nelumbinis extract, using it is preceding and using 2 weeks after the figure of photo now as shown in Figure 1, can be with from Fig. 1
Find out, volunteer is behind condensation 2 weeks containing nine grades of rank in the feudal regimes Flos Nelumbinis extract prepared using the embodiment of the present invention 1, and microgroove accounts for now
Than significantly reducing, dermatoglyph more expansion.
From in table 2~4 as can be seen that having effects that synergy between each ingredient of the present invention.Of the invention contains the nine grades of rank in the feudal regimes
The condensation of perfume Flos Nelumbinis extract have significantly smooth away wrinkles, smooth skin, calm antiallergic and whitening effect, effect is used for a long time
Fruit more preferably, can allow skin smooth it is compact, rich in gloss, color spot can also be removed, have preferable whitening effect.Simultaneously according to aspiration
Person's reaction does not find that product generates stimulation allergic phenomena to trier.
The above embodiment is a preferred embodiment of the present invention, but embodiments of the present invention are not by above-described embodiment
Limitation, other any changes, modifications, substitutions, combinations, simplifications made without departing from the spirit and principles of the present invention,
It should be equivalent substitute mode, be included within the scope of the present invention.
Claims (10)
1. a kind of condensation containing nine grades of rank in the feudal regimes perfume Flos Nelumbinis extract, it is characterised in that the component including following mass percent:
A1 component: glycerol 5%, xanthan gum 0.05%；
A2 component: water 62.87%；
A3 component: carbomer 0.2%；
B component: glycine betaine 0.5%, niacinamide 2%, water 5%；
C component: arginine 0.1%；
D component: dried tremella extract 1%, carboxymethylchitosan 0.2%, dendrobium candidum stem extraction 1%, nine grades of rank in the feudal regimes perfume
Flos Nelumbinis extract and Caulis Kadsurae Coccineae extract totally 10%；
E1 component: essence 0.02%, solubilizer 0.06%；
E2 component: water 10%；
F component: 1,3-BDO 1%, preservative 1%.
2. the condensation according to claim 1 containing nine grades of rank in the feudal regimes perfume Flos Nelumbinis extract, it is characterised in that:
The mass percent of the nine grades of rank in the feudal regimes perfume Flos Nelumbinis extract is 7%, and the mass percent of Caulis Kadsurae Coccineae extract is 3%.
3. the condensation according to claim 1 containing nine grades of rank in the feudal regimes perfume Flos Nelumbinis extract, it is characterised in that:
The mass percent of the nine grades of rank in the feudal regimes perfume Flos Nelumbinis extract is 5%, and the mass percent of Caulis Kadsurae Coccineae extract is 5%.
4. the condensation according to claim 1 containing nine grades of rank in the feudal regimes perfume Flos Nelumbinis extract, it is characterised in that:
The mass percent of the nine grades of rank in the feudal regimes perfume Flos Nelumbinis extract is 3%, and the mass percent of Caulis Kadsurae Coccineae extract is 7%.
5. the condensation according to any one of claims 1 to 4 containing nine grades of rank in the feudal regimes perfume Flos Nelumbinis extract, it is characterised in that:
The solubilizer is 1,3 butylene glycol；The preservative is PHL.
6. the condensation according to any one of claims 1 to 4 containing nine grades of rank in the feudal regimes perfume Flos Nelumbinis extract, it is characterised in that:
The nine grades of rank in the feudal regimes perfume Flos Nelumbinis extract is extracted to obtain by following methods:
(1) fresh nine grades of rank in the feudal regimes perfume lotus flower is taken, dries surface water after cleaning up, is added in tissue mashing machine and is homogenized into mucus
Shape adds water and stirs extraction into gained homogenate, then filters, and is 95% by mass concentration is added after the concentration of gained filtrate
Ethyl alcohol mixes well, and filters after precipitation to be precipitated, collects precipitating；
(2) gained is precipitated and is decolourized with addition active carbon after 50~80 DEG C of hot water dissolvings, be then filtered to remove active carbon, it will
The ethyl alcohol that mass concentration is 95% is added into concentrate, is centrifugated after mixing well, supernatant is gone to receive for the concentration of gained filtrate
Collection precipitating, it is dry to get nine grades of rank in the feudal regimes Flos Nelumbinis extract.
7. the condensation according to claim 6 containing nine grades of rank in the feudal regimes perfume Flos Nelumbinis extract, it is characterised in that:
In the extraction process of nine grades of rank in the feudal regimes perfume Flos Nelumbinis extract:
It is added water and stirred described in step (1) and refers to that 2h is extracted in the water stirring that 5~10 times of volumes are added；
The time of decoloration described in step (2) is 5~60min；The speed of centrifuge separation described in step (2) be 500~
3000r/min；Drying described in step (2) refers to be dried in vacuo at 50~80 DEG C；
The dosage for the ethyl alcohol that step (1) and addition mass concentration described in step (2) are 95% is the corresponding concentrate 5 of addition
The ethyl alcohol that the mass concentration of~10 times of volumes is 95%；
Concentration described in step (1) and step (2) refers both to be concentrated under reduced pressure into the 10~40% of original volume at 20~60 DEG C.
8. the condensation according to any one of claims 1 to 4 containing nine grades of rank in the feudal regimes perfume Flos Nelumbinis extract, it is characterised in that:
The Caulis Kadsurae Coccineae extract is extracted to obtain by following steps: being dried after black tiger is cleaned, is ground and cross 20~200 mesh
Sieve carries out refluxing extraction after 90% ethyl alcohol is added, then filters, by gained filtrate in 50 DEG C~85 DEG C vacuum drying to get black
Tiger extract.
9. the condensation according to claim 8 containing nine grades of rank in the feudal regimes perfume Flos Nelumbinis extract, it is characterised in that:
In the extraction process of the Caulis Kadsurae Coccineae extract, the drying refer to 40~60 DEG C dry 12~for 24 hours；Described adds
90% ethyl alcohol entered refers to be added by solid-liquid ratio 1:5~15；The time of the refluxing extraction is 1~5h.
10. a kind of preparation side of the condensations containing nine grades of rank in the feudal regimes perfume Flos Nelumbinis extract described in any item according to claim 1~9
Method, it is characterised in that the following steps are included:
(1) A1 component is uniformly mixed, A2 component is added and stirs evenly, adds A3 component and stirs evenly, 82 ± 5 DEG C add
Heat keeps the temperature 3-5min, and stirring is cooled to 43 ± 2 DEG C, for use；
(2) B component is added in the mixture obtained to step (1), stirs evenly, normal-temperature dissolution is stand-by；
(3) C component is added in the mixture obtained to step (2) to stir evenly, adds D component and stir evenly, adds E1
The mixture of component and E2 component, stirring at normal temperature are uniformly stand-by；
(4) F component is added in the mixture obtained to step (3) to stir evenly, is cooled to 30 ± 5 degree to system temperature, vacuum
Stirring；
(5) detection indices qualification discharging；
Mixing speed described in step (1)~(4) is 400~600rpm.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111494500A (en) * | 2020-05-15 | 2020-08-07 | 湖南环境生物职业技术学院 | Black tiger pericarp extract and preparation method and application thereof |
| CN113262190A (en) * | 2021-06-04 | 2021-08-17 | 浙江大学 | External composition for resisting skin aging and application thereof |
| CN113750017A (en) * | 2020-10-09 | 2021-12-07 | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | Method for preparing dendrobium nobile skin care product with whitening effect |
| CN114917160A (en) * | 2022-06-06 | 2022-08-19 | 青蛙王子（福建）婴童护理用品有限公司 | Nymphaea hybrid fermentation product with antioxidant, anti-inflammatory and repairing effects and preparation and application thereof |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104337725A (en) * | 2013-08-02 | 2015-02-11 | 中华全国供销合作总社南京野生植物综合利用研究院 | Skin whitening and moisturizing mask containing nymphaea hybrid extractives and preparing method thereof |
| CN106117387A (en) * | 2016-08-19 | 2016-11-16 | 广州潮徽化工科技有限公司 | A kind of low-molecular-weight tremella polysaccharide and preparation method and application |
| CN107213058A (en) * | 2017-06-06 | 2017-09-29 | 安徽吉乃尔电器科技有限公司 | A kind of preparation method of perfume lotus flower skin whitening, moisturizing emulsion |
| CN108030739A (en) * | 2017-12-15 | 2018-05-15 | 广东盛美化妆品有限公司 | A kind of condensation of the Herba Dendrobii extract containing iron sheet and preparation method thereof |
| CN108823261A (en) * | 2018-07-09 | 2018-11-16 | 华南协同创新研究院 | A kind of Ultra-low molecular weight Dendrobium officinale polysaccharide and its preparation and application |
| CN109021129A (en) * | 2018-07-10 | 2018-12-18 | 广西壮族自治区药用植物园 | The extracting method of black tiger fruit polysaccharide |
-
2019
- 2019-08-28 CN CN201910803016.9A patent/CN110420143B/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104337725A (en) * | 2013-08-02 | 2015-02-11 | 中华全国供销合作总社南京野生植物综合利用研究院 | Skin whitening and moisturizing mask containing nymphaea hybrid extractives and preparing method thereof |
| CN106117387A (en) * | 2016-08-19 | 2016-11-16 | 广州潮徽化工科技有限公司 | A kind of low-molecular-weight tremella polysaccharide and preparation method and application |
| CN107213058A (en) * | 2017-06-06 | 2017-09-29 | 安徽吉乃尔电器科技有限公司 | A kind of preparation method of perfume lotus flower skin whitening, moisturizing emulsion |
| CN108030739A (en) * | 2017-12-15 | 2018-05-15 | 广东盛美化妆品有限公司 | A kind of condensation of the Herba Dendrobii extract containing iron sheet and preparation method thereof |
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