CN106265254A - The Tricholoma matsutake (lto et lmai) Singer extract and its preparation method and application of skin can be repaired by whitening skin and preserving moisture - Google Patents
The Tricholoma matsutake (lto et lmai) Singer extract and its preparation method and application of skin can be repaired by whitening skin and preserving moisture Download PDFInfo
- Publication number
- CN106265254A CN106265254A CN201610711537.8A CN201610711537A CN106265254A CN 106265254 A CN106265254 A CN 106265254A CN 201610711537 A CN201610711537 A CN 201610711537A CN 106265254 A CN106265254 A CN 106265254A
- Authority
- CN
- China
- Prior art keywords
- lmai
- lto
- skin
- tricholoma matsutake
- singer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
Abstract
The present invention relates to a kind of to repair the Tricholoma matsutake (lto et lmai) Singer extract and its preparation method and application of skin by whitening skin and preserving moisture, it is faint yellow to filemot liquid, comprise water soluble and the composition of alcohol in butanediol, water and Tricholoma matsutake (lto et lmai) Singer, Determination of Polyphenols is 20～40g/L, proportion is 1.0110～1.0200, pH value is 3.5～5.5, and index of refraction is 1.3800～1.4000；Its preparation method is first with dissolving in the composition of alcohol and water in ethanol and water extraction Tricholoma matsutake (lto et lmai) Singer, filters, then be utilized respectively water soluble and the composition of alcohol in butanediol and water dissolution Tricholoma matsutake (lto et lmai) Singer after reclaiming ethanol, and then mix homogeneously concentrates refined；It is applied to composite skin care product；Compared with prior art, product of the present invention uses whole part extracting mode, retain the active component of natural Tricholoma matsutake (lto et lmai) Singer to greatest extent, whole extraction process is simple to operation, input cost is low, extraction effect is notable, and the safe non-hazardous of Tricholoma matsutake (lto et lmai) Singer extract, and whitening, reparation, moisturizing skin and antioxidative effect are more excellent, using rear skinfeel salubrious, skin is beautiful white with elasticity.
Description
Technical field
The present invention relates to skin care field, particularly relate to a kind of Tricholoma matsutake (lto et lmai) Singer extract and its preparation method and application.
Background technology
The design of the product of skin whitening at present is mainly realized by suppression tyrosinase activity, it has been reported that the most a large amount of
The tyrosinase inhibitor of natural origin, such as arbutin, kojic acid etc., had been demonstrated good clinical effectiveness, but along with people
Progress of research, find that melanic generation process has number of ways in fact, and have the participation of multiple enzyme, and melanic
Melanin distribution in skin and performance are also had a great impact by transfer process, and therefore the process of skin whitening should be not only
This approach is suppressed, if can act on from multiple mechanism simultaneously, it should more preferably whitening effect can be reached from tryrosinase
Really.But multipath acts on melanic generation and transfer process, it is necessary to consider that safety, otherwise skin can be had a strong impact on black
The normal physiological metabolism of pigment, therefore selects some active skull cap components, vitamin active composition to combine, with associating
Collaborative mode plays suppression melanin and generates and the effect of transfer, and can safeguard normal physiological metabolism and the function of skin,
Thus reach safe and effective whitening effect, have very important significance.
Tricholoma matsutake (lto et lmai) Singer (Tricholoma Matsutake Singer), formal name used at school Trichotoma matsutake, have another name called armillaria Matsutake, belong to country's second class protection
Plant.Tricholoma matsutake (lto et lmai) Singer is widely distributed in China northeast, southwest, and especially with Sichuan, Yunnan, Jilin great reputation the most, wherein Sichuan is refined
Jiang Songrong is because yield is high, head is big, meat is thin, color and luster is good, taste is fragrant deep by favor both domestic and external, Yajiang annual Tricholoma matsutake (lto et lmai) Singer collection capacity
Average annual up to more than 1000 tons, in the national not far numerous mountains of businessman ten thousand such as annual Japan, Korea S, come Yajiang purchase Tricholoma matsutake (lto et lmai) Singer.Tricholoma matsutake (lto et lmai) Singer this
Plant the famous and precious wild rare mycotrophy in plateau to enrich, containing multiple proteins, aminoacid, polysaccharide, vitamin and mineral, protecting
Extensively applying in health food and medicine, it has had building body, the most smooth stomach invigorating, activating QI to eliminate phlegm, pain relieving lot of documents report
Anthelmintic, suppression tumor and the effect such as anticancer；Application aspect data in cosmetics is less.
Summary of the invention
The technical problem to be solved is to provide and a kind of manufactures that processing is simple, input cost is low, skin effect is excellent
Different and have no side effect can repair the Tricholoma matsutake (lto et lmai) Singer extract and its preparation method and application of skin by whitening skin and preserving moisture.
The technical scheme is that
A kind of can whitening skin and preserving moisture repair skin Tricholoma matsutake (lto et lmai) Singer extract, it is faint yellow to filemot liquid, comprises fourth two
Water soluble and the composition of alcohol in alcohol, water and Tricholoma matsutake (lto et lmai) Singer, Determination of Polyphenols is 20～40g/L, its proportion be 1.0110～
1.0200, pH value is 3.5～5.5, and index of refraction is 1.3800～1.4000.
Compared with prior art, the invention has the beneficial effects as follows:
Product of the present invention uses whole part extracting mode, retains the active component of natural Tricholoma matsutake (lto et lmai) Singer to greatest extent, whole carries
The process that takes is simple to operation, input cost is low, and extraction effect is notable, and the safe non-hazardous of Tricholoma matsutake (lto et lmai) Singer extract, whitening, reparation,
Moisturizing skin and antioxidative effect are more excellent, use rear skinfeel salubrious, and skin is beautiful white with elasticity.
A kind of can repair the preparation method of Tricholoma matsutake (lto et lmai) Singer extract of skin by whitening skin and preserving moisture as above, it includes following step
Rapid: taking the section of wild Tricholoma matsutake (lto et lmai) Singer, air-dry, the Tricholoma matsutake (lto et lmai) Singer air dried sheet 1:2 in mass ratio～4 obtained adds in ethanol water, and impregnates
More than 24 hours, then circumfluence distillation 2～6 hours, and the circumfluence distillation thing obtained is refined, reclaim ethanol, then
Concentrating under reduced pressure, filtration, and the filtrate reduced in volume that will obtain, be refining to obtain B liquid, the most tolerant adds to butanediol by be filtrated to get
Aqueous solution dissolves, is refining to obtain A liquid, then A liquid is mixed homogeneously with B liquid, and under conditions of 2～8 DEG C, deposit 24～48h,
I.e. obtain described Tricholoma matsutake (lto et lmai) Singer extract.
Compared with prior art, the invention has the beneficial effects as follows:
In the present invention, Tricholoma matsutake (lto et lmai) Singer extract is chosen natural precious Yajiang Tricholoma matsutake (lto et lmai) Singer and is used whole part extracting mode to be prepared from, maximum
The active component retaining natural Tricholoma matsutake (lto et lmai) Singer of limit, the remarkable clinical effectiveness for it establishes material base, initially with ethanol water
Solution impregnation extraction more completely (ethanol water effect of extracting is more preferable, but if life-time service is containing the too much skin care item of ethanol,
Easily human skin is caused damage), then utilize circumfluence distillation mode, obtain on the premise of not destroying effective component of matsutake
Comprise the preliminary extract of the whole effective ingredient of Tricholoma matsutake (lto et lmai) Singer, removal ethanol of re-refining, it is to avoid skin care item contain ethanol and injured skin,
Last butanediol aqueous dissolution refines, and whole extraction process is simple to operation, input cost is low, and extraction effect is notable, can protect
Stay whole effective ingredient of Tricholoma matsutake (lto et lmai) Singer, and the safe non-hazardous of Tricholoma matsutake (lto et lmai) Singer extract, whitening, reparation, moisturizing skin and antioxidative effect
Fruit is more excellent, uses rear skinfeel salubrious, and skin is beautiful white with elasticity.
On the basis of technique scheme, the present invention can also do following improvement.
As a kind of preferred implementation of the present invention, described wild Tricholoma matsutake (lto et lmai) Singer section rear panel thickness is 3～5mm, and is not surpassing
Air-drying under conditions of crossing 60 DEG C, described filtering technique uses 60～80 mesh sieves.
Using above-mentioned preferred version to provide the benefit that: sheet thickness is 3～5mm, it is better, to greatest extent that dipping extracts
Extract wild Tricholoma matsutake (lto et lmai) Singer section in whole effective ingredient, under conditions of less than 60 DEG C air-dry can be prevented effectively from wild
Effective ingredient in Tricholoma matsutake (lto et lmai) Singer section, by high temperature, affects the skin effect of final product, and filtering technique uses 60～80 mesh sieves,
Effectively filtrate that is the most tolerant and that be dissolved in water water-fast in refined rear circumfluence distillation thing can be separated, thus convenient
Subsequent operation, for the most tolerant be used alone to human skin entirely without harm butanediol aqueous solution dissolve, then with filter
Liquid mixes, and the composite skin care product system obtained is more stable, and the whole effective ingredient solute effects in wild Tricholoma matsutake (lto et lmai) Singer are more
Good, whitening, reparation, moisturizing skin and antioxidative effect are more excellent.
As the another kind of preferred implementation of the present invention, in described ethanol water the mass concentration of ethanol be 75%～
95%, in described butanediol aqueous solution, the mass concentration of butanediol is 20%～40%.
Above-mentioned preferred version is used to provide the benefit that: to use the ethanol water dipping of 75%～95% to extract wild pine
Fine and soft section is more complete, can retain the active component of natural Tricholoma matsutake (lto et lmai) Singer to greatest extent, and the remarkable clinical effectiveness for it establishes thing
Matter basis；Use in the refined rear circumfluence distillation thing of butanediol aqueous dissolution of 20%～40% water-fast the most tolerant,
Not only solute effect is good, it is ensured that the composite skin care product system obtained after mixing with filtrate is more stable, in wild Tricholoma matsutake (lto et lmai) Singer
Whole effective ingredient solute effects more preferable, whitening, reparation, moisturizing skin and antioxidative effect are more excellent, and to people
Body safety does not endangers, without any side effects.
A kind of can repair the application of Tricholoma matsutake (lto et lmai) Singer extract of skin by whitening skin and preserving moisture as above, it is applied to skin care item combination
Thing, in parts by weight, described composite skin care product comprises following components: 0.2～5 part of Tricholoma matsutake (lto et lmai) Singer extract, 5～20 portions of Flos Rosae Rugosaes are pure
Dew, 0.5～2 part of tremella polysaccharide, 0.5～2 part of hyaluronic acid, 3～5 parts of butanediols, 3～5 parts of pentanediols and 61～87.8 parts go
Ionized water.
Compared with prior art, the invention has the beneficial effects as follows:
Composite skin care product in the present invention uses pure natural plant formula, and safe non-hazardous, its Tricholoma matsutake (lto et lmai) Singer extract has
Whitening, reparation, moisturizing skin, antioxidative effect, MEIGUI CHUNLU fragrance is pleasant, has awake skin, beautiful white, antiallergic effect, Tremella
Polysaccharide and hyaluronic acid have moisturizing lock water effect, and the mixture of butanediol and pentanediol can individually work in coordination with tremella polysaccharide with saturating
Bright matter acid moisturizing skin, can effectively organically combine Tricholoma matsutake (lto et lmai) Singer extract, MEIGUI CHUNLU one with tremella polysaccharide, hyaluronic acid again
Rise, it is ensured that while composition system is stable, promote MEIGUI CHUNLU, tremella polysaccharide, hyaluronic acid to assist with Tricholoma matsutake (lto et lmai) Singer extract
Same-action so that the assimilation effect of human skin is more preferable, is greatly promoted the skin whitening of the skin care compositions of the present invention, repairs flesh
Skin, moisturizing skin, slow down aging, antianaphylactic effect, use rear skinfeel salubrious, and skin is beautiful white with elasticity.
On the basis of technique scheme, the present invention can also do following improvement.
As a kind of preferred implementation of the present invention, the preparation method of described composite skin care product comprises the following steps:
A, heating and batch mixing
In parts by weight, first take 61～87.8 parts of deionized waters, heat while stirring, take 0.5～2 portion of Tremella the most respectively
Polysaccharide, 0.5～2 part of hyaluronic acid, 3～5 parts of butanediols and 3～5 parts of pentanediols add, and mix homogeneously is the most tentatively mixed
Liquid；
B, vacuum homogenizing stand with constant temperature
By the preliminary mixed liquor constant temperature homogenizing under vacuum described in step A, then constant temperature stands, and is i.e. stood
Liquid；
C, stir, feed and vacuum homogenizing
Standing liquid described in first whipping step B, carries out lowering the temperature for the first time, more in parts by weight, takes 0.2～5 part of Tricholoma matsutake (lto et lmai) Singer
Extract and 5～20 parts of MEIGUI CHUNLU add, and carry out second time and lower the temperature after mix homogeneously, and then vacuum homogenizing i.e. obtains homogenizing
Mixed liquor；
D, vacuum stirring and discharging
Intimate mixing liquid described in step C is stirred under vacuum, then releases vacuum, detect liquid pH value,
If pH value is less than 3.5 or more than 5.5, then continuing to stir under vacuum, if pH value is 3.5～5.5, then discharging, during discharging
Filter, take filtrate, i.e. obtain the described composite skin care product with whitening, reparation, moisture-keeping efficacy.
Above-mentioned preferred version is used to provide the benefit that:
The preparation method of the composite skin care product in the present invention with whitening, reparation, moisture-keeping efficacy uses pure natural plant
Formula, safe non-hazardous, preparation process is simple to operation, input cost is low, first by tremella polysaccharide, hyaluronic acid, butanediol and
Pentanediol is dissolved in the hot water (heating while stirring) of even water temperature, and mix homogeneously stands after vacuum constant temperature homogenizing, effectively protects
Card butanediol and pentanediol can work in coordination with effect of tremella polysaccharide and hyaluronic acid performance moisturizing skin, and moistening effect is more excellent
Different, add Tricholoma matsutake (lto et lmai) Singer extract and MEIGUI CHUNLU after cooling, homogenizing after mix homogeneously, composition system was both effectively ensured and had kept steady
Fixed, Tricholoma matsutake (lto et lmai) Singer extract can be promoted again to play synergism with MEIGUI CHUNLU, tremella polysaccharide, hyaluronic acid, make the suction of human skin
Fruit of producing effects is more preferable, is greatly promoted the skin whitening of the skin care compositions of the present invention, reparation skin, moisturizing skin, slow down aging, resists
The effect of allergy, uses rear skinfeel salubrious, and skin is beautiful white with elasticity.
As the another kind of preferred implementation of the present invention, in step, deionization is stirred with the rotating speed of 5～10r/min
Water, and it is heated to 75～85 DEG C；After charging with 50～60r/min mixing speed mix homogeneously.
Above-mentioned preferred version is used to provide the benefit that: tremella polysaccharide, hyaluronic acid, butanediol and pentanediol to be dissolved into
In the hot water (stirring at low speed, water temperature control at 75～85 DEG C) of even water temperature, speed-raising stirring after charging, then after vacuum constant temperature homogenizing
Stand, significantly more efficient guarantee butanediol, pentanediol and tremella polysaccharide, hyaluronic acid can play synergism, be greatly improved
Moisturizing skin effect of compositions, is avoided that again the effective ingredient of tremella polysaccharide and hyaluronic acid is by high temperature.
As the another kind of preferred implementation of the present invention, in stepb, described preliminary mixed liquor in vacuum is
0.03～0.04Mpa, constant temperature homogenizing 2～4min under conditions of rotating speed is 3000r/min, constant temperature stands 15～25min.
Use above-mentioned preferred version to provide the benefit that: preliminary mixed liquor vacuum constant temperature homogenizing with this understanding, and stand
A period of time, butanediol, pentanediol and tremella polysaccharide, hyaluronic acid can preferably dissolve combination, play synergistic effect
Becoming apparent from, composition system is more stable.
As the another kind of preferred implementation of the present invention, in step C, the rotating speed with 30～40r/min stirs and stands
Liquid, is for the first time cooled to 50～60 DEG C during cooling, is cooled to 40～50 DEG C during second time cooling, is then 3000r/ at rotating speed
Vacuum homogenizing 1min under conditions of min.
Above-mentioned preferred version is used to provide the benefit that: to add Tricholoma matsutake (lto et lmai) Singer extract and MEIGUI CHUNLU after cooling, the most effectively
Ensure that composition system keeps stable, it is to avoid the effective ingredient of Tricholoma matsutake (lto et lmai) Singer extract and MEIGUI CHUNLU, again can be more by high temperature
Effectively promote Tricholoma matsutake (lto et lmai) Singer extract to play synergism with MEIGUI CHUNLU, tremella polysaccharide, hyaluronic acid, make the absorption of human skin
Effect is more preferable, is greatly improved the skin-care effect of compositions.
As the another kind of preferred implementation of the present invention, in step D, described intimate mixing liquid in vacuum is
0.05Mpa, rotating speed are stirring under conditions of 50～60r/min, cross 120 mesh sieves during discharging.
Use above-mentioned preferred version to provide the benefit that: preferably to ensure the quality of discharging product, obtain have whitening,
Repair, the composite skin care product skin effect of moisture-keeping efficacy excellent and without any side effects.
Below the preferred forms of the present invention is described in further details.
A kind of can whitening skin and preserving moisture repair skin Tricholoma matsutake (lto et lmai) Singer extract, it is faint yellow to filemot liquid, comprises fourth two
Water soluble and the composition of alcohol in alcohol, water and Tricholoma matsutake (lto et lmai) Singer, Determination of Polyphenols is 20～40g/L, its proportion be 1.0110～
1.0200, pH value is 3.5～5.5, and index of refraction is 1.3800～1.4000.
A kind of can repair the preparation method of Tricholoma matsutake (lto et lmai) Singer extract of skin by whitening skin and preserving moisture as above, it includes following step
Rapid: to take wild Tricholoma matsutake (lto et lmai) Singer section (ensureing that sheet thickness reaches 3～5mm), and air-dry under conditions of less than 60 DEG C, the Tricholoma matsutake (lto et lmai) Singer wind obtained
Dry tablet 1:2 in mass ratio～4 adds in ethanol water (ethanol mass concentration is 75%～95%), and impregnate 24 hours with
On, then circumfluence distillation 2～6 hours, and the circumfluence distillation thing obtained is refined, reclaim ethanol, then concentrating under reduced pressure,
Use 60～80 mesh screen, and the filtrate reduced in volume that will obtain, be refining to obtain B liquid, the most tolerant add to be filtrated to get
Butanediol aqueous solution (butanediol mass concentration is 20%～40%) dissolves, is refining to obtain A liquid, then A liquid is mixed with B liquid
Uniformly, and under conditions of 2～8 DEG C, deposit 24～48h, i.e. obtain described Tricholoma matsutake (lto et lmai) Singer extract.
A kind of can repair the application of Tricholoma matsutake (lto et lmai) Singer extract of skin by whitening skin and preserving moisture as above, it is applied to skin care item combination
Thing, described composite skin care product comprises following components: 0.2～5 part of Tricholoma matsutake (lto et lmai) Singer extract, 5～20 parts of MEIGUI CHUNLU, 0.5～2 part of silver
Fungus polysaccharides, 0.5～2 part of hyaluronic acid, 3～5 parts of butanediols, 3～5 parts of pentanediols and 61～87.8 parts of deionized waters；
The preparation method of described composite skin care product comprises the following steps:
A, heating and batch mixing
In parts by weight, first take 61～87.8 parts of deionized waters, with 5～10r/min rotating speed stir, and be heated to 75～
85 DEG C, take 0.5～2 part of tremella polysaccharide, 0.5～2 part of hyaluronic acid, 3～5 parts of butanediols and 3～5 parts of pentanediols the most respectively and add
Enter, with the mixing speed mix homogeneously of 50～60r/min, i.e. obtain preliminary mixed liquor；
B, vacuum homogenizing stand with constant temperature
By the preliminary mixed liquor described in step A vacuum be 0.03～0.04Mpa, rotating speed be 3000r/min's
Under the conditions of constant temperature homogenizing 2～4min, then constant temperature stand 15～25min, i.e. obtain stand liquid；
C, stir, feed and vacuum homogenizing
The first standing liquid described in the rotating speed whipping step B with 30～40r/min, carries out lowering the temperature for the first time, is cooled to 50
～60 DEG C, more in parts by weight, take 0.2～5 part of Tricholoma matsutake (lto et lmai) Singer extract and 5～20 parts of MEIGUI CHUNLU add, carry out after mix homogeneously
Second time cooling, is cooled to 40～50 DEG C, then vacuum homogenizing 1min under conditions of rotating speed is 3000r/min, i.e. obtains all
Matter mixed liquor；
D, vacuum stirring and discharging
By the intimate mixing liquid described in step C vacuum be 0.05Mpa, under conditions of rotating speed is 50～60r/min
Stirring, then releases vacuum, detects liquid pH value, if pH value is less than 3.5 or more than 5.5, then continue at 0.05Mpa, rotating speed be
Stir under conditions of 50～60r/min, if pH value is 3.5～5.5, then discharging, cross 120 mesh sieves during discharging, take filtrate, i.e. obtain
The described composite skin care product with whitening, reparation, moisture-keeping efficacy.
Detailed description of the invention
Principle and feature to the present invention are described below, and example is served only for explaining the present invention, is not intended to limit
Determine the scope of the present invention.
Embodiment 1
A kind of can whitening skin and preserving moisture repair skin Tricholoma matsutake (lto et lmai) Singer extract, it is faint yellow to filemot liquid, comprises fourth two
Water soluble and the composition of alcohol in alcohol, water and Tricholoma matsutake (lto et lmai) Singer, Determination of Polyphenols is 20g/L, and its proportion is 1.0110, and pH value is
5.5, index of refraction is 1.3800.
A kind of can repair the preparation method of Tricholoma matsutake (lto et lmai) Singer extract of skin by whitening skin and preserving moisture as above, it includes following step
Rapid: taking wild Tricholoma matsutake (lto et lmai) Singer section (ensureing that sheet thickness reaches 3mm), and air-dry under conditions of 60 DEG C, the Tricholoma matsutake (lto et lmai) Singer air dried sheet obtained is by matter
Amount adds in ethanol water (ethanol mass concentration is 75%) than 1:2, and impregnates more than 24 hours, then circumfluence distillation 2
Hour, and the circumfluence distillation thing obtained is refined, reclaim ethanol, then concentrating under reduced pressure, use 60 mesh screen, and incite somebody to action
The filtrate reduced in volume arrived, is refining to obtain B liquid, the most tolerant add to butanediol aqueous solution by be filtrated to get (butanediol quality is dense
Degree is 20%) middle dissolving, it is refining to obtain A liquid, then A liquid is mixed homogeneously with B liquid, and deposit 24h under conditions of 8 DEG C, to obtain final product
To described Tricholoma matsutake (lto et lmai) Singer extract.
A kind of can repair the application of Tricholoma matsutake (lto et lmai) Singer extract of skin by whitening skin and preserving moisture as above, it is applied to skin care item combination
Thing, described composite skin care product comprises following components: 0.2 part of Tricholoma matsutake (lto et lmai) Singer extract, 5 parts of MEIGUI CHUNLU, 0.5 part of tremella polysaccharide, 0.5
Part hyaluronic acid, 3 parts of butanediols, 3 parts of pentanediols and 61 parts of deionized waters；
The preparation method of described composite skin care product comprises the following steps:
A, heating and batch mixing
In parts by weight, first take 61g deionized water, stir with the rotating speed of 5r/min, and be heated to 75 DEG C, take the most respectively
0.5g tremella polysaccharide, 0.5g hyaluronic acid, 3g butanediol and 3g pentanediol add, with the mixing speed mix homogeneously of 50r/min,
I.e. obtain preliminary mixed liquor；
B, vacuum homogenizing stand with constant temperature
By the preliminary mixed liquor described in step A vacuum be 0.03Mpa, rotating speed be 3000r/min under conditions of permanent
Temperature homogenizing 2min, then constant temperature stands 15min, i.e. obtains standing liquid；
C, stir, feed and vacuum homogenizing
The first standing liquid described in the rotating speed whipping step B with 30r/min, carries out lowering the temperature for the first time, is cooled to 50 DEG C, takes
0.2g Tricholoma matsutake (lto et lmai) Singer extract and 5g MEIGUI CHUNLU add, and carry out second time and lower the temperature, be cooled to 40 DEG C, then at rotating speed after mix homogeneously
For vacuum homogenizing 1min under conditions of 3000r/min, i.e. obtain intimate mixing liquid；
D, vacuum stirring and discharging
By the intimate mixing liquid described in step C vacuum be 0.05Mpa, rotating speed be 50r/min under conditions of stir
Mix, then release vacuum, detect liquid pH value, if pH value is less than 3.5 or more than 5.5, then continue at 0.05Mpa, rotating speed be
Stirring under conditions of 50r/min, the discharging when pH value is 3.5～5.5, during discharging, pH value is 5.5, crosses 120 mesh sieves, takes filtrate,
I.e. obtain the described composite skin care product with whitening, reparation, moisture-keeping efficacy.
Embodiment 2
A kind of can whitening skin and preserving moisture repair skin Tricholoma matsutake (lto et lmai) Singer extract, it is characterised in that it is faint yellow to filemot liquid
Body, comprises water soluble and the composition of alcohol in butanediol, water and Tricholoma matsutake (lto et lmai) Singer, and Determination of Polyphenols is 30g/L, and its proportion is
1.0155, pH value is 4.5, and index of refraction is 1.3900.
A kind of can repair the preparation method of Tricholoma matsutake (lto et lmai) Singer extract of skin by whitening skin and preserving moisture as above, it includes following step
Rapid: taking wild Tricholoma matsutake (lto et lmai) Singer section (ensureing that sheet thickness reaches 4mm), and air-dry under conditions of 50 DEG C, the Tricholoma matsutake (lto et lmai) Singer air dried sheet obtained is by matter
Amount adds in ethanol water (ethanol mass concentration is 85%) than 1:3, and impregnates 36 hours, then circumfluence distillation 4 hours,
And the circumfluence distillation thing obtained is refined, reclaim ethanol, then concentrating under reduced pressure, use 70 mesh screen, and will obtain
Filtrate reduced in volume, is refining to obtain B liquid, the most tolerant add to butanediol aqueous solution by be filtrated to get (butanediol mass concentration is
30%) dissolve in, be refining to obtain A liquid, then A liquid mixed homogeneously with B liquid, and deposit 36h under conditions of 5 DEG C, i.e. obtain institute
The Tricholoma matsutake (lto et lmai) Singer extract stated.
A kind of can repair the application of Tricholoma matsutake (lto et lmai) Singer extract of skin by whitening skin and preserving moisture as above, it is applied to skin care item combination
Thing, described composite skin care product comprises following components: 2.6g Tricholoma matsutake (lto et lmai) Singer extract, 12.5g MEIGUI CHUNLU 1.25g tremella polysaccharide,
1.25g hyaluronic acid, 4g butanediol, 4g pentanediol and 74.4g deionized water；
The preparation method of described composite skin care product comprises the following steps:
A, heating and batch mixing
First take 74.4g deionized water, stir with the rotating speed of 7.5r/min, and be heated to 80 DEG C, take 1.25g silver the most respectively
Fungus polysaccharides, 1.25g hyaluronic acid, 4g butanediol and 4g pentanediol add, and with the mixing speed mix homogeneously of 55r/min, to obtain final product
To preliminary mixed liquor；
B, vacuum homogenizing stand with constant temperature
By the preliminary mixed liquor described in step A vacuum be 0.035Mpa, under conditions of rotating speed is 3000r/min
Constant temperature homogenizing 3min, then constant temperature stands 20min, i.e. obtains standing liquid；
C, stir, feed and vacuum homogenizing
The first standing liquid described in the rotating speed whipping step B with 35r/min, carries out lowering the temperature for the first time, is cooled to 55 DEG C, takes
2.6g Tricholoma matsutake (lto et lmai) Singer extract and 12.5g MEIGUI CHUNLU add, and carry out second time and lower the temperature, be cooled to 45 DEG C, then exist after mix homogeneously
Rotating speed is vacuum homogenizing 1min under conditions of 3000r/min, i.e. obtains intimate mixing liquid；
D, vacuum stirring and discharging
By the intimate mixing liquid described in step C vacuum be 0.05Mpa, rotating speed be 55r/min under conditions of stir
Mix, then release vacuum, detect liquid pH value, if pH value is less than 3.5 or more than 5.5, then continue at 0.05Mpa, rotating speed be
Stirring under conditions of 55r/min, the discharging when pH value is 3.5～5.5, during discharging, pH value is 4.5, crosses 120 mesh sieves, takes filtrate,
I.e. obtain the described composite skin care product with whitening, reparation, moisture-keeping efficacy.
Embodiment 3
A kind of can whitening skin and preserving moisture repair skin Tricholoma matsutake (lto et lmai) Singer extract, it is characterised in that it is faint yellow to filemot liquid
Body, comprises water soluble and the composition of alcohol in butanediol, water and Tricholoma matsutake (lto et lmai) Singer, and Determination of Polyphenols is 40g/L, and its proportion is
1.0200, pH value is 3.5, and index of refraction is 1.4000.
A kind of can repair the preparation method of Tricholoma matsutake (lto et lmai) Singer extract of skin by whitening skin and preserving moisture as above, it includes following step
Rapid: taking wild Tricholoma matsutake (lto et lmai) Singer section (ensureing that sheet thickness reaches 5mm), and air-dry under conditions of 40 DEG C, the Tricholoma matsutake (lto et lmai) Singer air dried sheet obtained is by matter
Amount adds in ethanol water (ethanol mass concentration is 95%) than 1:4, and impregnates 48 hours, then circumfluence distillation 6 hours,
And the circumfluence distillation thing obtained is refined, reclaim ethanol, then concentrating under reduced pressure, use 80 mesh screen, and will obtain
Filtrate reduced in volume, is refining to obtain B liquid, the most tolerant add to butanediol aqueous solution by be filtrated to get (butanediol mass concentration is
40%) dissolve in, be refining to obtain A liquid, then A liquid mixed homogeneously with B liquid, and deposit 48h under conditions of 2 DEG C, i.e. obtain institute
The Tricholoma matsutake (lto et lmai) Singer extract stated.
A kind of can repair the application of Tricholoma matsutake (lto et lmai) Singer extract of skin by whitening skin and preserving moisture as above, it is applied to skin care item combination
Thing, described composite skin care product comprises following components: 5g Tricholoma matsutake (lto et lmai) Singer extract, 20g MEIGUI CHUNLU, 2g tremella polysaccharide, 2g hyalomitome
Acid, 5g butanediol, 5g pentanediol and 87.8g deionized water；
The preparation method of described composite skin care product comprises the following steps:
A, heating and batch mixing
First take 87.8g deionized water, stir with the rotating speed of 10r/min, and be heated to 85 DEG C, take 2g Tremella the most respectively many
Sugar, 2g hyaluronic acid, 5g butanediol and 5g pentanediol add, and with the mixing speed mix homogeneously of 60r/min, are the most tentatively mixed
Close liquid；
B, vacuum homogenizing stand with constant temperature
By the preliminary mixed liquor described in step A vacuum be 0.04Mpa, rotating speed be 3000r/min under conditions of permanent
Temperature homogenizing 4min, then constant temperature stands 25min, i.e. obtains standing liquid；
C, stir, feed and vacuum homogenizing
The first standing liquid described in the rotating speed whipping step B with 40r/min, carries out lowering the temperature for the first time, is cooled to 60 DEG C, takes
5g Tricholoma matsutake (lto et lmai) Singer extract and 20g MEIGUI CHUNLU add, and carry out second time and lower the temperature, be cooled to 50 DEG C, then at rotating speed after mix homogeneously
For vacuum homogenizing 1min under conditions of 3000r/min, i.e. obtain intimate mixing liquid；
D, vacuum stirring and discharging
By the intimate mixing liquid described in step C vacuum be 0.05Mpa, rotating speed be 60r/min under conditions of stir
Mix, then release vacuum, detect liquid pH value, if pH value is less than 3.5 or more than 5.5, then continue at 0.05Mpa, rotating speed be
Stirring under conditions of 60r/min, the discharging when pH value is 3.5～5.5, during discharging, pH value is 3.5, crosses 120 mesh sieves, takes filtrate,
I.e. obtain the described composite skin care product with whitening, reparation, moisture-keeping efficacy.
Embodiment 4
The Tricholoma matsutake (lto et lmai) Singer extract a of skin and skin care item group can be repaired by whitening skin and preserving moisture to what embodiment 1 to embodiment 3 obtained
Compound b carries out the test of human body skin closed patch irritant experiment, and test result is as follows:
To embodiment 1 to embodiment 3 obtains can whitening skin and preserving moisture repair skin Tricholoma matsutake (lto et lmai) Singer extract a be diluted to matter respectively
Amount concentration is 0.2%, 2.6%, 5%, then carries out whitening effect with the composite skin care product b that obtains in embodiment 1 to embodiment 3
Fruit test (i.e. testing its inhibitory action to TYR enzyme), and select light water to carry Tricholoma matsutake (lto et lmai) Singer liquid c to carry out whitening effect test
Controlled trial, it is 5% that light water puies forward the mass concentration of Tricholoma matsutake (lto et lmai) Singer liquid c, and test result is as follows:
To embodiment 1 to embodiment 3 obtains can whitening skin and preserving moisture repair skin Tricholoma matsutake (lto et lmai) Singer extract a be diluted to matter respectively
Amount concentration is 0.2%, 2.6%, 5%, then carries out antiallergic with the composite skin care product b that obtains in embodiment 1 to embodiment 3 and disappears
Scorching measure of merit (i.e. testing its inhibitory action to hyaluronidase), and select light water to carry Tricholoma matsutake (lto et lmai) Singer liquid c to carry out antiallergic antiinflammatory
The controlled trial of measure of merit, it is 5% that light water puies forward the mass concentration of Tricholoma matsutake (lto et lmai) Singer liquid c, and test result is as follows:
To embodiment 1 to embodiment 3 obtains can whitening skin and preserving moisture repair skin Tricholoma matsutake (lto et lmai) Singer extract a be diluted to matter respectively
Amount concentration is 0.2%, 2.6%, 5%, then carries out antioxidation with the composite skin care product b that obtains in embodiment 1 to embodiment 3
Measure of merit (surveys oxidation resistance by DPPH method), and selects light water to carry Tricholoma matsutake (lto et lmai) Singer liquid c to carry out antioxidant effect test, commonly
Water carries Tricholoma matsutake (lto et lmai) Singer liquid c and uses boiling water extraction, and it is 5% that mass concentration controls, and test result is as follows:
To embodiment 1 to embodiment 3 obtains can whitening skin and preserving moisture repair skin Tricholoma matsutake (lto et lmai) Singer extract a be diluted to matter respectively
Amount concentration is 0.2%, 2.6%, 5%, then carries out moisturizing effect with the composite skin care product b that obtains in embodiment 1 to embodiment 3
Fruit test (surveys the moistening effect of Tricholoma matsutake (lto et lmai) Singer extract) by Corneometer method, and test result is as follows:
In sum, the Tricholoma matsutake (lto et lmai) Singer extract in the present invention and composite skin care product use pure natural plant formula, safety
Non-hazardous, hence it is evident that there is the multi-efficiencies such as whitening, reparation, moisturizing skin, antioxidation, with after skin can be made beautiful white with elasticity,
Skin effect is more more significantly than conventional skin care product.
It is obvious to a person skilled in the art that the invention is not restricted to the details of above-mentioned one exemplary embodiment, Er Qie
In the case of the spirit or essential attributes of the present invention, it is possible to realize the present invention in other specific forms.Therefore, no matter
From the point of view of which point, all should regard embodiment as exemplary, and be nonrestrictive, the scope of the present invention is by appended power
Profit requires rather than described above limits, it is intended that all by fall in the implication of equivalency and scope of claim
Change is included in the present invention.
The foregoing is only presently preferred embodiments of the present invention, not in order to limit the present invention, all spirit in the present invention and
Within principle, any modification, equivalent substitution and improvement etc. made, should be included within the scope of the present invention.
Claims (10)
1. one kind can whitening skin and preserving moisture repair skin Tricholoma matsutake (lto et lmai) Singer extract, it is characterised in that it is faint yellow to filemot liquid,
Comprising water soluble and the composition of alcohol in butanediol, water and Tricholoma matsutake (lto et lmai) Singer, Determination of Polyphenols is 20～40g/L, and its proportion is
1.0110～1.0200, pH value is 3.5～5.5, and index of refraction is 1.3800～1.4000.
2. can repair the preparation method of Tricholoma matsutake (lto et lmai) Singer extract of skin by whitening skin and preserving moisture as claimed in claim 1, its feature exists
In, it comprises the following steps: taking the section of wild Tricholoma matsutake (lto et lmai) Singer, air-dry, the Tricholoma matsutake (lto et lmai) Singer air dried sheet 1:2 in mass ratio～4 obtained adds to ethanol
In aqueous solution, and impregnate more than 24 hours, then circumfluence distillation 2～6 hours, and the circumfluence distillation thing obtained is carried out essence
System, reclaims ethanol, then concentrating under reduced pressure, filtration, and the filtrate reduced in volume that will obtain, is refining to obtain B liquid, will be filtrated to get not
Tolerant adding to is dissolved in butanediol aqueous solution, is refining to obtain A liquid, is then mixed homogeneously with B liquid by A liquid, and the condition of 2～8 DEG C
Under deposit 24～48h, i.e. obtain described Tricholoma matsutake (lto et lmai) Singer extract.
The most according to claim 2 can repair the preparation method of Tricholoma matsutake (lto et lmai) Singer extract of skin by whitening skin and preserving moisture, it is characterised in that
Described wild Tricholoma matsutake (lto et lmai) Singer section rear panel thickness is 3～5mm, and air-dries under conditions of less than 60 DEG C, and described filtering technique uses 60
～80 mesh sieves.
The most according to claim 2 can repair the preparation method of Tricholoma matsutake (lto et lmai) Singer extract of skin by whitening skin and preserving moisture, it is characterised in that
In described ethanol water, the mass concentration of ethanol is 75%～95%, the mass concentration of butanediol in described butanediol aqueous solution
It is 20%～40%.
5. can repair the application of Tricholoma matsutake (lto et lmai) Singer extract of skin by whitening skin and preserving moisture as claimed in claim 1 for one kind, it is characterised in that it
Being applied to composite skin care product, in parts by weight, described composite skin care product comprises following components: 0.2～5 part of described Tricholoma matsutake (lto et lmai) Singer
Extract, 5～20 parts of MEIGUI CHUNLU, 0.5～2 part of tremella polysaccharide, 0.5～2 part of hyaluronic acid, 3～5 parts of butanediols, 3～5 parts
Pentanediol and 61～87.8 parts of deionized waters.
The most according to claim 5 can repair the application of Tricholoma matsutake (lto et lmai) Singer extract of skin by whitening skin and preserving moisture, it is characterised in that described
The preparation method of composite skin care product comprises the following steps:
A, heating and batch mixing
In parts by weight, first take 61～87.8 parts of deionized waters, heat while stirring, take 0.5～2 portion of Tremella the most respectively many
Sugar, 0.5～2 part of hyaluronic acid, 3～5 parts of butanediols and 3～5 parts of pentanediols add, and mix homogeneously i.e. obtains preliminary mixed liquor；
B, vacuum homogenizing stand with constant temperature
By the preliminary mixed liquor constant temperature homogenizing under vacuum described in step A, then constant temperature stands, and i.e. obtains standing liquid；
C, stir, feed and vacuum homogenizing
Standing liquid described in first whipping step B, carries out lowering the temperature for the first time, more in parts by weight, takes 0.2～5 part of Tricholoma matsutake (lto et lmai) Singer and extract
Thing and 5～20 parts of MEIGUI CHUNLU add, and carry out second time and lower the temperature after mix homogeneously, and then vacuum homogenizing i.e. obtains intimate mixing
Liquid；
D, vacuum stirring and discharging
Intimate mixing liquid described in step C is stirred under vacuum, then releases vacuum, detect liquid pH value, if pH
Value less than 3.5 or more than 5.5, then continues to stir under vacuum, if pH value is 3.5～5.5, then and discharging, filter during discharging,
Take filtrate, i.e. obtain the described composite skin care product with whitening, reparation, moisture-keeping efficacy.
The most according to claim 6 can repair the application of Tricholoma matsutake (lto et lmai) Singer extract of skin by whitening skin and preserving moisture, it is characterised in that in step
In rapid A, with the rotating speed agitating deionized water of 5～10r/min, and it is heated to 75～85 DEG C；With 50～60r/min stir after charging
Mix speed mix homogeneously.
The most according to claim 6 can repair the application of Tricholoma matsutake (lto et lmai) Singer extract of skin by whitening skin and preserving moisture, it is characterised in that in step
In rapid B, described preliminary mixed liquor vacuum be 0.03～0.04Mpa, constant temperature is equal under conditions of rotating speed is 3000r/min
Matter 2～4min, constant temperature stands 15～25min.
The most according to claim 6 can repair the application of Tricholoma matsutake (lto et lmai) Singer extract of skin by whitening skin and preserving moisture, it is characterised in that in step
In rapid C, the rotating speed with 30～40r/min stirs and stands liquid, is cooled to 50～60 DEG C for the first time during cooling, fall during second time cooling
Warm to 40～50 DEG C, then vacuum homogenizing 1min under conditions of rotating speed is 3000r/min.
The most according to claim 6 can repair the application of Tricholoma matsutake (lto et lmai) Singer extract of skin by whitening skin and preserving moisture, it is characterised in that
In step D, described intimate mixing liquid vacuum be 0.05Mpa, rotating speed be to stir under conditions of 50～60r/min, discharging
Time cross 120 mesh sieves.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610711537.8A CN106265254A (en) | 2016-08-23 | 2016-08-23 | The Tricholoma matsutake (lto et lmai) Singer extract and its preparation method and application of skin can be repaired by whitening skin and preserving moisture |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610711537.8A CN106265254A (en) | 2016-08-23 | 2016-08-23 | The Tricholoma matsutake (lto et lmai) Singer extract and its preparation method and application of skin can be repaired by whitening skin and preserving moisture |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106265254A true CN106265254A (en) | 2017-01-04 |
Family
ID=57615741
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610711537.8A Pending CN106265254A (en) | 2016-08-23 | 2016-08-23 | The Tricholoma matsutake (lto et lmai) Singer extract and its preparation method and application of skin can be repaired by whitening skin and preserving moisture |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106265254A (en) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110559226A (en) * | 2019-09-12 | 2019-12-13 | 广州雨昕生物技术有限公司 | Whitening lotion and preparation method thereof |
| CN111110616A (en) * | 2020-01-17 | 2020-05-08 | 云南白药集团股份有限公司 | Preparation method of tricholoma matsutake whitening mask liquid |
| CN111110614A (en) * | 2020-01-17 | 2020-05-08 | 云南白药集团股份有限公司 | Skin whitening effect of tricholoma matsutake extract composition |
| CN111467267A (en) * | 2019-01-24 | 2020-07-31 | 考希德芭以奥帕株式会社 | Cosmetic composition containing plant extract and effective in moisturizing cell, cell and skin |
| CN111728886A (en) * | 2020-07-13 | 2020-10-02 | 植物医生(广东)生物科技有限公司 | Whitening composition and preparation method and application thereof |
| CN114940948A (en) * | 2022-04-12 | 2022-08-26 | 天津尚美化妆品有限公司 | Tricholoma matsutake and tricholoma matsutake mycelium fermentation medium and preparation method of fermentation liquid |
| WO2023284221A1 (en) * | 2021-07-15 | 2023-01-19 | 广州环亚化妆品科技股份有限公司 | Composition with soothing and repairing effects, and preparation method therefor and use thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004224702A (en) * | 2003-01-20 | 2004-08-12 | Ichimaru Pharcos Co Ltd | External preparation for skin containing mushroom extract |
| CN102895172A (en) * | 2012-10-22 | 2013-01-30 | 无限极（中国）有限公司 | Matsutake extract with functions of resisting aging, moisturizing and promoting penetration and preparation method and application thereof |
| CN105411919A (en) * | 2015-12-01 | 2016-03-23 | 武汉光阴树生态科技有限公司 | Skin caring product made from roses and preparation method thereof |
-
2016
- 2016-08-23 CN CN201610711537.8A patent/CN106265254A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004224702A (en) * | 2003-01-20 | 2004-08-12 | Ichimaru Pharcos Co Ltd | External preparation for skin containing mushroom extract |
| CN102895172A (en) * | 2012-10-22 | 2013-01-30 | 无限极（中国）有限公司 | Matsutake extract with functions of resisting aging, moisturizing and promoting penetration and preparation method and application thereof |
| CN105411919A (en) * | 2015-12-01 | 2016-03-23 | 武汉光阴树生态科技有限公司 | Skin caring product made from roses and preparation method thereof |
Non-Patent Citations (2)
| Title |
|---|
| 宋丽雅等编: "《化妆品植物功效添加剂的研究与开发》", 30 September 2011, 中国轻工业出版社 * |
| 邓影妹等: "松口蘑活性物提取工艺研究及其安全功效评价", 《日用化学工业》 * |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111467267A (en) * | 2019-01-24 | 2020-07-31 | 考希德芭以奥帕株式会社 | Cosmetic composition containing plant extract and effective in moisturizing cell, cell and skin |
| CN110559226A (en) * | 2019-09-12 | 2019-12-13 | 广州雨昕生物技术有限公司 | Whitening lotion and preparation method thereof |
| CN111110616A (en) * | 2020-01-17 | 2020-05-08 | 云南白药集团股份有限公司 | Preparation method of tricholoma matsutake whitening mask liquid |
| CN111110614A (en) * | 2020-01-17 | 2020-05-08 | 云南白药集团股份有限公司 | Skin whitening effect of tricholoma matsutake extract composition |
| CN111728886A (en) * | 2020-07-13 | 2020-10-02 | 植物医生(广东)生物科技有限公司 | Whitening composition and preparation method and application thereof |
| WO2023284221A1 (en) * | 2021-07-15 | 2023-01-19 | 广州环亚化妆品科技股份有限公司 | Composition with soothing and repairing effects, and preparation method therefor and use thereof |
| CN114940948A (en) * | 2022-04-12 | 2022-08-26 | 天津尚美化妆品有限公司 | Tricholoma matsutake and tricholoma matsutake mycelium fermentation medium and preparation method of fermentation liquid |
| CN114940948B (en) * | 2022-04-12 | 2023-10-20 | 天津尚美化妆品有限公司 | Tricholoma matsutake and tricholoma matsutake mycelium fermentation medium and preparation method of fermentation broth |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN106265254A (en) | The Tricholoma matsutake (lto et lmai) Singer extract and its preparation method and application of skin can be repaired by whitening skin and preserving moisture | |
| CN106667837A (en) | Camellia oleifera component based body lotion and preparation method thereof | |
| CN102293292B (en) | Health tea with functions of yin nourishing and blood nourishing, and processing method thereof | |
| JP7269370B2 (en) | Palm ginseng extraction method and related palm ginseng extract | |
| CN109528603A (en) | Lightening compositions, whitening brightening cream comprising lightening compositions and preparation method thereof | |
| CN106880563B (en) | A kind of Chinese medicine skin whitening, moisturizing gel frost and preparation method thereof | |
| CN110037981A (en) | A kind of skin care item and the preparation method and application thereof | |
| CN110420143A (en) | A kind of condensation and preparation method thereof containing nine grades of rank in the feudal regimes perfume Flos Nelumbinis extract | |
| CN104026262A (en) | Health care sesame oil capable of nourishing liver to improve visual acuity, and preparation method thereof | |
| CN104083317A (en) | White bud tea eye care cream and preparation method thereof | |
| KR20150145992A (en) | Composition for red ginseng mask pack, the manufacturing method thereof, and the mask pack manufactured thereby | |
| CN104825365A (en) | Ginseng skin whitening facial mask and preparation method thereof | |
| CN108158884A (en) | With the cosmetic material composition and its application in cosmetics for inhibiting allergy, function of delaying senility | |
| CN107157800A (en) | One kind is releived maintenance multiple-effect facial mask | |
| CN104586700A (en) | Vitex negundo linn leaf extract and preparation method as well as application thereof | |
| CN109223908A (en) | Composition and purposes rich in green-tea extract and Chinese medical extract | |
| CN108143668A (en) | It is a kind of that there are skin care item for improving aging skin appearance and preparation method thereof | |
| CN107440995A (en) | A kind of pure natural lipstick containing traditional Chinese medicine ingredients and preparation method thereof | |
| CN103462855A (en) | Cosmetic containing American ginseng and longan and preparation method thereof | |
| CN107494862B (en) | Cosmetic coffee containing periplaneta americana active ingredient | |
| CN105441230A (en) | Camellia oil cold processed soap | |
| CN111714423B (en) | Traditional Chinese medicine composition extract with anti-aging and allergy-relieving effects and preparation method and application thereof | |
| CN107213077A (en) | A kind of preparation method of Chinese herbal medicine ferment shampoo | |
| CN112870141A (en) | Edible natural plant skin-care mask lotion and preparation method thereof | |
| CN112618441A (en) | Anti-allergy whitening moisturizing composition and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20170104 |
|
| RJ01 | Rejection of invention patent application after publication |