CN107308030A - A kind of anti-aging reinforcing gel cream - Google Patents

A kind of anti-aging reinforcing gel cream Download PDF

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Publication number
CN107308030A
CN107308030A CN201710436144.5A CN201710436144A CN107308030A CN 107308030 A CN107308030 A CN 107308030A CN 201710436144 A CN201710436144 A CN 201710436144A CN 107308030 A CN107308030 A CN 107308030A
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aging
flavones
gel cream
oil
mulberry leaves
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鲁翠容
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Foshan Huili Cosmetics Science And Technology Co Ltd
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Foshan Huili Cosmetics Science And Technology Co Ltd
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Priority to CN201710436144.5A priority Critical patent/CN107308030A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4946Imidazoles or their condensed derivatives, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A61K8/498Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • A61K8/602Glycosides, e.g. rutin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/86Polyethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18

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  • Gerontology & Geriatric Medicine (AREA)
  • Dermatology (AREA)
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  • Microbiology (AREA)
  • Mycology (AREA)
  • Cosmetics (AREA)

Abstract

The present invention relates to a kind of anti-aging reinforcing gel cream, including following mass percent component:Vegetable oil:1 8%, NMF:10 28%, water-soluble fullerene:0.01 5%, flavones in mulberry leaves:0.1 5%, Cordceps militaris extract:0.1 5%, emulsifying agent:0.5 3%, thickener:0.1 3%, conditioner:0.1 0.5%.The water-soluble fullerene that the present invention is used has good antioxygenic property, can effective scavenging capacity oxygen radical, activating skin cells, pre- anti-aging;Flavones in mulberry leaves and Cordceps militaris extract are respectively provided with good in vitro anti-oxidation, and unnecessary oxygen radical can be removed from cell interior, plays a part of antioxidant and anti-aging, prevents free radical damage skin;Play the role of Synergistic in formula between each component, with moisturizing, anti-oxidant, antibacterial, anti-aging, prevent microgroove the effects such as.

Description

A kind of anti-aging reinforcing gel cream
Technical field
The present invention relates to cosmetic field, a kind of anti-aging reinforcing gel cream is specifically related to.
Background technology
Aging (Aging) is also known as aging, is the only stage which must be passed by any biological life active process, be organismal development into After ripe, increase with the age and occur it is progressive, influenceed by inherent cause, the morphosis that whole body is complicated and physiological function not Reversible degenerative process.Skin is the maximum organ of human body, is responsible for protection, sensation, regulation body temperature, secretion, excretion and is immunized Etc. all many effects, with advancing age, skin also can the gradually aging as other organs of human body, function subtracts Weak, forfeiture, produces various lesions etc..
The skin of aging, hence it is evident that be characterized as that cutis laxa and wrinkle occur, body exposure portion skin becomes coarse, wrinkle Deepen overstriking;Epidermal structure exception, pigmentation, appearance " senile plaque expelling ";Elasticity of skin no longer, become loose;Blood vessel dilatation, table Skin dyskeratosis etc..Slow down in the skin mesocuticle cell turnover of aging, barrier function weakens, under keratinocyte vigor Drop, repair ability weakens after haveing a superficial wound, and the decrease of wherein barrier function causes dry skin, furfur, wrinkle etc..
The free radical of peroxidating can be produced in internal many substance metabolism processes, when the Radical Metabolism in body is in not During poised state, excessive free radical will cause body injury, and unrighted acid is oxidized into superoxides, form fat brown Element.Oxygen radical excessively can also destroy cell membrane and other important components, make protein and enzyme denaturation, when damage caused by free radical When wound accumulation defeats the repair ability of body, it may result in the change of cell differentiation state, even lose, so as to cause and add Fast aging.Cause the excessive factor of interior free yl a lot, can be largely classified into two aspects:1. oneself factor, such as human body from The reason such as radical scavenging activity declines in right ageing process, organism endocrine imbalance, immunologic function decline produce it is excessive from By base;2. outside environmental elements, such as illumination, radiation, depressed, pressure are excessive, nervous, tobacco and wine are stimulated and bad environments Deng can all cause Radical Metabolism in body to be in non-equilibrium state, cause interior free yl excessive.
The A of Chinese patent application CN 102871944 disclose a kind of natural anti-aging face cream, by following weight Raw material is constituted:5~15 parts of glycerine, 1~10 part of ethanol, vitamin e acetate 2~8,0.1~1 part of methyl hydroxybenzoate, plant carries Take 5~25 parts of liquid, 1~3 part of vitamin B6,0.5~1.5 part of hyaluronic acid, 0.5~2.5 part of essence.Described plant extraction liquid For one or more of mixtures in radix glycyrrhizae, cordate houttuynia, Chinese gall, the tuber of multiflower knotweed, ginseng or prune extract.The day of the invention Right anti-aging face cream, it contains various active nutritional ingredient, easily allows bacterium to corrode, and causes the pollution of face cream.
The content of the invention
The present invention according to the deficiencies in the prior art there is provided a kind of anti-aging reinforcing gel cream, it is clear from water-soluble fullerene Except active oxygen radical, activating skin cells, pre- anti-aging, coordinate reached with flavones in mulberry leaves and Cordceps militaris extract it is anti-oxidant anti- The effect of aging, plays a part of Synergistic.
To achieve the above object, the present invention is adopted the following technical scheme that:
A kind of anti-aging reinforcing gel cream of the present invention, including following mass percent component:
Vegetable oil:1-8%;
NMF:10-28%;
Water-soluble fullerene:0.01-5%;
Flavones in mulberry leaves:0.1-5%;
Cordceps militaris extract:0.1-5%;
Emulsifying agent:0.5-3%;
Thickener:0.1-3%;
Conditioner:0.1-0.5%;
The preparation process of the flavones in mulberry leaves is crushed to 50-100 mesh, uses 50-90% second to take mulberry leaf dried leaf 5-10g Alcohol is as Extraction solvent, and solid-liquid ratio is 1:30, fixed ultrasonic power 300W, ultrasonic extraction 10-120min, suction filtration at 40-80 DEG C It is placed in after centrifugation on Rotary Evaporators and is concentrated into medicinal extract, flavones in mulberry leaves is obtained after vacuum freeze drying;
The Cordceps militaris extract dries medicinal material 8-15kg to weigh Cordceps militaris, is crushed to 50-100 mesh, plus deionized water 80-120L, is heated to after 80-90 DEG C, immersion 30-120min, extract solution is collected by filtration, its residue distills plus same component is stated It is heated to after water after 80-90 DEG C, immersion 30-120min, filtering merges above-mentioned soaked extracting solution, extract solution is concentrated under reduced pressure into 3-5L。
In a preferred embodiment of the invention, a kind of described anti-aging reinforcing gel cream, including following quality percentage Compare component:
Vegetable oil:3-6%;
NMF:15-20%;
Water-soluble fullerene:1-4%;
Flavones in mulberry leaves:2-3%;
Cordceps militaris extract:1.5-3.4%;
Emulsifying agent:1.2-2.5%;
Thickener:1.2-2.2%;
Conditioner:0.2-0.4%;
In a preferred embodiment of the invention, the vegetable oil is SIMMONDSIA CHINENSIS SEED OIL, grape-kernel oil, palm oil, sweet tea apricot At least one of benevolence oil, olive oil, coconut oil.
In a preferred embodiment of the invention, the NMF is glycerine, butanediol, polyethylene glycol, sorbierite, thoroughly At least one of the sour sodium of bright matter, amino acid humectant.
In a preferred embodiment of the invention, the emulsifying agent be cetostearyl alcohol/cetearyl glucoside and Stearine/PEG-100 stearates are (0.25-1.6) in proportion:The mixture of (0.9-1.8).
In a preferred embodiment of the invention, the thickener is at least one in carbomer, xanthans, guar gum Kind.
In a preferred embodiment of the invention, the conditioner is allantoin.
It is INCI (International Nomenclature to point out above-mentioned each components of cosmetics title CosmeticIngredient, i.e. international cosmetic raw material are named) title of defined.
Mulberry leaf are the dried leaf of moraceae plants mulberry (Morus alba L.).It is cold in nature, sweet-bitter flavor, with dispelling wind and heat from the body, clearing lung-heat The function of moisturize, clearing liver and improving vision, is traditional medicinal and edible Chinese medicine, is widely used for a long time by among the people, and have accumulated abundant Invaluable experience.The pharmacological component of mulberry leaf is various, contains steroidal and triterpene compound, flavones, cumarin, volatile oil, life The multiple compounds such as alkaloids, amino acid, it has hypoglycemic, reducing blood lipid, scavenging activated oxygen, anti-infective and antiviral etc. make With.
Cordceps militaris, also known as northern Chinese caterpillar Fungus, Cordyceps militaris, are Ascomycotina gang pyrenomycetes Sphaerials Clavicipitaceae Cordyceps, Xenogenesis is belonged to together with cordyceps sinensis.《Chinese medicine sea》Record:" pupa grass, nature and flavor are sweet, flat, enter lung, kidney two warp.”《National Chinese herbal medicine converges Compile》Record:" fructification and pupal cell of Cordyceps militaris (Cordceps militaris) can also be used as medicine as cordyceps sinensis." contain cordyceps sinensis in Cordceps militaris The nutrients such as element, cordycepic acid, Cordyceps sinensis polysaccharide and abundant protein, 18 kinds of amino acid, 17 kinds of trace elements, 12 kinds of vitamin Matter, wherein vitamin A, B1, B2, B6, B12, C, D, E equal size are higher than mushroom class.Cordceps militaris extract has delay skin aging Effect.
In the 1980s, the mankind are found that C60, the new stage recognized carbon is thus opened, stone is being found that in succession After ink, diamond, the third simple substance existed with carbon crystal form is found.C60It is that there is uniqueness containing numerous double bonds The three-dimensional aromatic compound of cagelike structure.The carbon atom that its 60 are located on summit constitutes spherical 32 face body, wherein having 12 Individual face is pentagon, and 20 faces are hexagons.This structure is similar to the football seen in daily life, therefore also referred to as " football alkene ".This special structure makes it have the excellent property such as special superconduction, ferromagnetism, high pressure resistant, resist chemical Matter.Had a extensive future in fields such as superconductor, photoconductive material, cosmetics, nanometer particle material, biomedicines.
It is well known that vitamin C has inoxidizability.But fullerene C60Oxidation resistance be ascorbic 125 times. In addition to antioxidation, fullerene C60Can also effective scavenging capacity oxygen radical, activating skin cells, pre- anti-aging etc. Effect.
Compared with prior art, beneficial effects of the present invention are:1. water-soluble fullerene has good antioxygenic property, can With effective scavenging capacity oxygen radical, activating skin cells, pre- anti-aging;2. flavones in mulberry leaves and Cordceps militaris extract are respectively provided with Good in vitro anti-oxidation, unnecessary oxygen radical can be removed from cell interior, plays a part of antioxidant and anti-aging, is prevented Free radical damage skin;3. play the role of Synergistic between each component in formula, with moisturizing, anti-oxidant, antibacterial, anti-aging, The effects such as preventing microgroove.
Embodiment
With reference to specific embodiment, the present invention is described in further detail.
Embodiment 1
Mulberry leaf dried leaf 5g is taken, 50 mesh are crushed to, with 50% ethanol as Extraction solvent, solid-liquid ratio is 1:30, it is fixed super Acoustical power 300W, ultrasonic extraction 10min at 40 DEG C, is placed on Rotary Evaporators after suction filtration centrifugation and is concentrated into medicinal extract, cold through vacuum It is lyophilized it is dry after flavones in mulberry leaves;
Embodiment 2
Mulberry leaf dried leaf 7.5g is taken, 75 mesh are crushed to, with 70% ethanol as Extraction solvent, solid-liquid ratio is 1:30, it is fixed Ultrasonic power 300W, ultrasonic extraction 65min at 60 DEG C, is placed on Rotary Evaporators after suction filtration centrifugation and is concentrated into medicinal extract, through vacuum Flavones in mulberry leaves is obtained after freeze-drying;
Embodiment 3
Mulberry leaf dried leaf 10g is taken, 100 mesh are crushed to, with 90% ethanol as Extraction solvent, solid-liquid ratio is 1:30, it is fixed Ultrasonic power 300W, ultrasonic extraction 120min at 80 DEG C, is placed on Rotary Evaporators after suction filtration centrifugation and is concentrated into medicinal extract, through vacuum Flavones in mulberry leaves is obtained after freeze-drying;
Embodiment 4
Take Cordceps militaris to dry medicinal material 8kg, be crushed to 50 mesh, plus deionized water 80L, be heated to after 80 DEG C, immersion 30min, Extract solution is collected by filtration, its residue is added to state and is heated to after same component distilled water after 80 DEG C, immersion 30min, filtering, in merging Soaked extracting solution is stated, extract solution is concentrated under reduced pressure into 3L.
Embodiment 5
Take Cordceps militaris to dry medicinal material 11kg, be crushed to 75 mesh, plus deionized water 100L, be heated to 85 DEG C, soak 75min Afterwards, extract solution is collected by filtration, its residue is added to state and is heated to after same component distilled water after 85 DEG C, immersion 75min, is filtered, is closed And above-mentioned soaked extracting solution, extract solution is concentrated under reduced pressure into 4L.
Embodiment 6
Take Cordceps militaris to dry medicinal material 15kg, be crushed to 100 mesh, plus deionized water 120L, be heated to 90 DEG C, soak 120min Afterwards, extract solution is collected by filtration, its residue is added to state and is heated to after same component distilled water after 90 DEG C, immersion 120min, is filtered, is closed And above-mentioned soaked extracting solution, extract solution is concentrated under reduced pressure into 5L.
Embodiment 7~11
A kind of 5 specific embodiments of anti-aging reinforcing gel cream of the present invention are listed in table 1.
Flavones in mulberry leaves and Cordceps militaris extract in embodiment 7-8 derive from above-described embodiment 1 and embodiment 4;Embodiment 9 In flavones in mulberry leaves and Cordceps militaris extract derive from above-described embodiment 2 and embodiment 5;Flavones in mulberry leaves in embodiment 10-11 Above-described embodiment 3 and embodiment 6 are derived from Cordceps militaris extract.
Table 1
A kind of 6 specific comparative examples of anti-aging reinforcing gel cream of the present invention are listed in table 2.
Table 2
Evaluation test on probation
Preferably to prove that a kind of anti-aging reinforcing gel cream provided by the present invention has excellent effect, embodiment is chosen 7th, 8,9,10,11 and reference examples 1,2,3,4,5,6 carry out further on probation investigation and evaluation test.Embodiment is as follows:Choosing 110 special volunteers are taken, age distribution is 30-58 Sui.The wherein people of male 45, the people of women 65.Evaluation survey is carried out to embodiment Examination, each sampling phase is three months, and object on probation is facial drying, skin is rougher or the tool more crowd of microgroove.
Subject is cleaned after face, skin of neck sooner or later, is taken and is uniformly applied to face and skin of neck in right amount, gently massages To fully absorbing.
Table 3 is test index and result.
Table 3
As a result show:
From table 3, the number that embodiment 7-11 dry skins, elasticity, smoothness and microgroove are obviously improved is substantially more In comparative example 1-6, show for facial drying, skin is rougher or has the more crowd of microgroove, and this hair was used at continuous three months The face cream of bright containing water-soluble fullerene, flavones in mulberry leaves and Cordceps militaris extract, Skin Dryness, elasticity, smoothness and tiny wrinkle The effect that line is significantly improved.And embodiment 9 has the best effect being obviously improved, embodiment 9 is matched somebody with somebody for the present invention is optimal Side.The dry skin of comparative example 1 is obviously improved number for 4 people, and skin elasticity is obviously improved number for 3 people, and skin smoothness is obvious Improvement number is 4 people, and skin lines are obviously improved number for 5 people, show a kind of main work(of anti-aging reinforcing gel cream of the invention Effect composition is water-soluble fullerene, flavones in mulberry leaves and Cordceps militaris extract.Comparative example 1-4 contrasts the visible present invention with embodiment 9 Water-soluble fullerene, flavones in mulberry leaves and Cordceps militaris extract have the effect of Synergistic.From the point of view of assessment result on probation, this hair It is bright that there is significant effect in terms of Skin Dryness, elasticity, microgroove, smoothness is improved, illustrate using of the invention one section After time, skin of face holistic health degree can be made to obtain a certain degree of lifting.In addition there is not allergy or related in subject And the phenomenon of skin lesion, i.e., security of the present invention is preferable.
The foregoing is only a preferred embodiment of the present invention, but protection scope of the present invention be not limited thereto, Any one skilled in the art is in the technical scope of present disclosure, the change or replacement that can be readily occurred in, It should all be included within the scope of the present invention.Therefore, protection scope of the present invention should be with the protection of claims Scope is defined.

Claims (8)

1. a kind of anti-aging reinforcing gel cream, including following mass percent component:Vegetable oil:1-8%, NMF:10-28%, Water-soluble fullerene:0.01-5%, flavones in mulberry leaves:0.1-5%, Cordceps militaris extract:0.1-5%, emulsifying agent:0.5-3%, increasing Thick dose:0.1-3%, conditioner:0.1-0.5%;
The preparation process of the flavones in mulberry leaves is crushed to 50-100 mesh to take mulberry leaf dried leaf 5-10g, is made with 50-90% ethanol For Extraction solvent, solid-liquid ratio is 1:30, fixed ultrasonic power 300W, ultrasonic extraction 10-120min, suction filtration centrifugation at 40-80 DEG C After be placed on Rotary Evaporators and be concentrated into medicinal extract, after vacuum freeze drying flavones in mulberry leaves;
The Cordceps militaris extract dries medicinal material 8-15kg to weigh Cordceps militaris, is crushed to 50-100 mesh, plus deionized water 80- 120L, is heated to after 80-90 DEG C, immersion 30-120min, filters 2-3 times, collect extract solution, its residue adds and states same component It is heated to after distilled water after 80-90 DEG C, immersion 30-120min, filters 2-3 times, merge above-mentioned soaked extracting solution, extract solution is subtracted Pressure is concentrated into 3-5L.
2. anti-aging reinforcing gel cream according to claim 1, including following mass percent component:Vegetable oil:3-6%, NMF:15-20%, water-soluble fullerene:1-4%, flavones in mulberry leaves:2-3%, Cordceps militaris extract:1.5-3.4%, emulsification Agent:1.2-2.5%, thickener:1.2-2.2%, conditioner:0.2-0.4%.
3. anti-aging reinforcing gel cream according to claim 1 or 2, it is characterised in that the vegetable oil is SIMMONDSIA CHINENSIS SEED OIL, Portugal At least one of grape seed oil, palm oil, Sweet Almond Oil, olive oil, coconut oil.
4. anti-aging reinforcing gel cream according to claim 1 or 2, it is characterised in that the NMF is glycerine, fourth two At least one of alcohol, polyethylene glycol, sorbierite, Sodium Hyaluronate, amino acid humectant.
5. anti-aging reinforcing gel cream according to claim 1 or 2, it is characterised in that the emulsifying agent be cetostearyl alcohol/ Cetearyl glucoside and stearine/PEG-100 stearates are (0.25-1.6) in proportion:(0.9-1.8's) Mixture.
6. anti-aging reinforcing gel cream according to claim 1 or 2, it is characterised in that the thickener is carbomer, xanthan At least one of glue, guar gum.
7. anti-aging reinforcing gel cream according to claim 1 or 2, it is characterised in that the conditioner is allantoin.
8. anti-aging reinforcing gel cream according to claim 1 or 2, it is characterised in that including following mass percent component: Water-soluble fullerene:2.5%th, amino acid humectant:1%th, glycerine:13.3%th, Sodium Hyaluronate:0.7%th, SIMMONDSIA CHINENSIS SEED OIL: 3%th, Sweet Almond Oil:1.5%th, flavones in mulberry leaves:2.5%th, Cordceps militaris extract:2.5%th, cetostearyl alcohol/cetearyl Portugal Glucosides:1.6%th, stearine/PEG-100 stearates:0.9%th, xanthans:1.7%th, allantoin:0.3%.
CN201710436144.5A 2017-06-09 2017-06-09 A kind of anti-aging reinforcing gel cream Withdrawn CN107308030A (en)

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Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107811962A (en) * 2017-11-23 2018-03-20 佛山微赢电子商务有限公司 Eyes are not stimulated with cleaning bubble with makeup removing skin care effect and preparation method thereof
CN108186679A (en) * 2018-02-07 2018-06-22 中国科学院化学研究所 A kind of acne-removing composition
CN108185435A (en) * 2018-02-22 2018-06-22 钱卫民 A kind of Sang Ju Yin bacterium product and preparation method and application
CN108888573A (en) * 2018-08-06 2018-11-27 李媛媛 Shu Min moisturizing frost and preparation method thereof
CN110974726A (en) * 2019-12-31 2020-04-10 福建省梦娇兰日用化学品有限公司 Infant skin cream based on ultrasonic assistance
CN112022784A (en) * 2020-09-28 2020-12-04 南京慧智莲华科技有限公司 Removable fragrant toner and preparation method thereof
CN114432215A (en) * 2021-11-02 2022-05-06 广州雷诺生物科技有限公司 Repair cream containing fullerene and preparation method thereof
CN114588090A (en) * 2022-04-06 2022-06-07 常熟理工学院 Cordyceps militaris anti-aging moisturizing emulsion and preparation method thereof
CN115197856A (en) * 2022-09-08 2022-10-18 山东锦鲤生物工程有限公司 Cordyceps militaris strain and application thereof

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107811962A (en) * 2017-11-23 2018-03-20 佛山微赢电子商务有限公司 Eyes are not stimulated with cleaning bubble with makeup removing skin care effect and preparation method thereof
CN108186679A (en) * 2018-02-07 2018-06-22 中国科学院化学研究所 A kind of acne-removing composition
CN108186679B (en) * 2018-02-07 2020-08-04 中国科学院化学研究所 Acne removing composition
CN108185435A (en) * 2018-02-22 2018-06-22 钱卫民 A kind of Sang Ju Yin bacterium product and preparation method and application
CN108888573A (en) * 2018-08-06 2018-11-27 李媛媛 Shu Min moisturizing frost and preparation method thereof
CN108888573B (en) * 2018-08-06 2021-11-19 吉安智企企业服务有限公司 Soothing and moisturizing cream and preparation method thereof
CN110974726A (en) * 2019-12-31 2020-04-10 福建省梦娇兰日用化学品有限公司 Infant skin cream based on ultrasonic assistance
CN112022784A (en) * 2020-09-28 2020-12-04 南京慧智莲华科技有限公司 Removable fragrant toner and preparation method thereof
CN114432215A (en) * 2021-11-02 2022-05-06 广州雷诺生物科技有限公司 Repair cream containing fullerene and preparation method thereof
CN114588090A (en) * 2022-04-06 2022-06-07 常熟理工学院 Cordyceps militaris anti-aging moisturizing emulsion and preparation method thereof
CN115197856A (en) * 2022-09-08 2022-10-18 山东锦鲤生物工程有限公司 Cordyceps militaris strain and application thereof

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