CN112368298A - 嵌合跨膜蛋白及其用途 - Google Patents

嵌合跨膜蛋白及其用途 Download PDF

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CN112368298A
CN112368298A CN201980042055.XA CN201980042055A CN112368298A CN 112368298 A CN112368298 A CN 112368298A CN 201980042055 A CN201980042055 A CN 201980042055A CN 112368298 A CN112368298 A CN 112368298A
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amino acids
nucleotides
receptor
seq
sequence
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P.埃姆塔奇
G.罗梅因
R.文森特
S.怀曼
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Kite Pharma Inc
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Kite Pharma Inc
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CN201980042055.XA 2018-06-22 2019-06-21 嵌合跨膜蛋白及其用途 Pending CN112368298A (zh)

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US201862688810P 2018-06-22 2018-06-22
US62/688,810 2018-06-22
PCT/US2019/038547 WO2019246563A1 (en) 2018-06-22 2019-06-21 Chimeric transmembrane proteins and uses thereof

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EP (1) EP3810645A1 (enExample)
JP (1) JP2021527689A (enExample)
KR (1) KR20210025525A (enExample)
CN (1) CN112368298A (enExample)
AU (2) AU2019288733C1 (enExample)
BR (1) BR112020025804A2 (enExample)
CA (1) CA3102641A1 (enExample)
IL (1) IL279505A (enExample)
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CN113736810A (zh) * 2021-09-08 2021-12-03 阿思科力(苏州)生物科技有限公司 构建体、载体、蛋白、细胞、制备方法、产品及应用
WO2023197980A1 (zh) * 2022-04-11 2023-10-19 苏州沙砾生物科技有限公司 一种嵌合抗原受体及其应用
CN117402231A (zh) * 2023-12-14 2024-01-16 南方医科大学南方医院 一种自发传递il-21信号的受体及其应用
WO2024051831A1 (zh) * 2022-09-09 2024-03-14 信达细胞制药(苏州)有限公司 组成型嵌合细胞因子受体及表达其的免疫细胞及应用

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US11629340B2 (en) 2017-03-03 2023-04-18 Obsidian Therapeutics, Inc. DHFR tunable protein regulation
EP4714966A2 (en) 2017-09-26 2026-03-25 Cero Therapeutics Holdings, Inc. Chimeric engulfment receptor molecules and methods of use
CN111819192A (zh) 2018-03-02 2020-10-23 艾洛基治疗公司 可诱导的嵌合细胞激素受体
EP3774906A1 (en) 2018-03-28 2021-02-17 Cero Therapeutics, Inc. Chimeric tim4 receptors and uses thereof
MX2020010241A (es) 2018-03-28 2020-10-16 Cero Therapeutics Inc Composiciones de inmunoterapia celular y usos de las mismas.
US11866494B2 (en) * 2018-08-31 2024-01-09 Innovative Cellular Therapeutics Holdings, Ltd. CAR T therapy through uses of co-stimulation
AU2020232216B2 (en) 2019-03-01 2025-09-25 Allogene Therapeutics, Inc. Chimeric cytokine receptors bearing a PD-1 ectodomain
PE20211902A1 (es) 2019-03-01 2021-09-27 Allogene Therapeutics Inc Receptores de citocinas quimericos constitutivamente activos
CN114391021B (zh) 2019-06-21 2026-01-16 凯德药业股份有限公司 TGF-β受体和使用方法
GB201911187D0 (en) 2019-08-05 2019-09-18 Autolus Ltd Receptor
US12528856B2 (en) 2019-08-30 2026-01-20 Allogene Therapeutics, Inc. Chimeric cytokine receptors comprising TGF β binding domains
US20210253696A1 (en) * 2020-01-21 2021-08-19 Cero Therapeutics, Inc. Bivalent chimeric engulfment receptors and uses thereof
MX2022010340A (es) 2020-02-24 2022-09-19 Allogene Therapeutics Inc Celulas t con car de bcma con actividades mejoradas.
US11661459B2 (en) 2020-12-03 2023-05-30 Century Therapeutics, Inc. Artificial cell death polypeptide for chimeric antigen receptor and uses thereof
KR20230118887A (ko) 2020-12-03 2023-08-14 센츄리 쎄라퓨틱스 인코포레이티드 유전자 조작 세포 및 이의 용도
AR124414A1 (es) 2020-12-18 2023-03-22 Century Therapeutics Inc Sistema de receptor de antígeno quimérico con especificidad de receptor adaptable
EP4305053A1 (en) * 2021-03-11 2024-01-17 Kite Pharma, Inc. Improving immune cell function
WO2022261061A1 (en) 2021-06-08 2022-12-15 Kite Pharma, Inc. Gpc3 binding molecules
KR20240022575A (ko) * 2021-06-16 2024-02-20 센티 바이오사이언시스, 인코포레이티드 아머링된 키메라 수용체 및 이의 사용 방법
JPWO2023276395A1 (enExample) * 2021-06-28 2023-01-05
CN117402262A (zh) * 2022-10-19 2024-01-16 上海君赛生物科技有限公司 基于lag3的嵌合免疫细胞辅助受体及其用途
IL322949A (en) 2023-03-03 2025-10-01 Arsenal Biosciences Inc Systems targeting PSMA and CA9
WO2026008700A1 (en) * 2024-07-03 2026-01-08 Immunofusion Bv Il7r alpha signalling domain, chimeric antigen receptor and uses thereof

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