CN111631981A - Composition with anti-wrinkle effect, cosmetic and application of composition - Google Patents
Composition with anti-wrinkle effect, cosmetic and application of composition Download PDFInfo
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- CN111631981A CN111631981A CN202010564623.7A CN202010564623A CN111631981A CN 111631981 A CN111631981 A CN 111631981A CN 202010564623 A CN202010564623 A CN 202010564623A CN 111631981 A CN111631981 A CN 111631981A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
Abstract
The invention relates to the technical field of cosmetics, in particular to a composition with an anti-wrinkle effect, a cosmetic and an application thereof, and the composition with the anti-wrinkle effect is characterized in that: the composite material comprises the following components in percentage by mass: the composition with the anti-wrinkle effect has the advantages that the composition with the anti-wrinkle effect has the instant external effect and the long-term internal repair effect, can achieve the effects of quickly removing wrinkles and assisting in internal multi-dimensional conditioning, meanwhile has the synergistic effect, and can achieve the purposes of quickly, durably and cheaply slowing down and removing skin fine lines and fishtail lines around eyes.
Description
Technical Field
The invention relates to the technical field of cosmetics, and particularly relates to a composition with an anti-wrinkle effect, a cosmetic and an application of the composition.
Background
Wrinkles are roughly divided into: dynamic wrinkles, gravitational wrinkles. The dynamic wrinkles are generated by the long-term contraction of expression muscles and are mainly expressed in the eyebrow lifting lines of the frontal muscles, the glabellar lines of the frown muscles, the crow's feet lines of the orbicularis oculi muscles, the angulus oris lines and the erect lines of the lips of the orbicularis oris muscles, the cheek twills of the zygomatic major muscles and the upper labial quadratus, and the like; the gravity wrinkles are mainly generated by subcutaneous tissue fat, muscle and skeleton atrophy and the long-term action of the gravity and gravity after the skin is aged.
Wrinkles are the most visual appearance of human aging, and how to quickly and effectively inhibit the generation and deepening of the wrinkles becomes the pursuit of various beauty-loving people. At present, rapid wrinkle removal in the market is generally realized by injecting botulinus, skin stretching and laser, which have certain risks, require regular maintenance and are expensive.
Disclosure of Invention
In view of the above, the present invention aims to avoid the disadvantages in the prior art, and provides a composition with an anti-wrinkle effect, which has an immediate external effect and a long-term internal repair effect, can achieve the effects of quickly removing wrinkles, assisting in multi-dimensional conditioning of the interior, and also has a synergistic effect, and can achieve the purposes of quickly, durably and cheaply slowing down to remove fine wrinkles on the skin and crow's feet around the eyes.
The embodiment of the invention provides a composition with an anti-wrinkle effect, which comprises the following components in percentage by mass: 0.1-5% of tremella polysaccharide, 0.01-2% of hydrolyzed sodium hyaluronate, 1-20% of beta-glucan, 0.01-5% of acetyl hexapeptide-80.01%, 0.01-5% of carnosine and 63-98.87% of water.
White fungus polysaccharide: can promote the synthesis of protein and nucleic acid and enhance the self-repairing ability.
Hydrolysis of sodium hyaluronate: has a small molecular weight, can permeate into the stratum corneum and then provide nutrition, and has excellent moisturizing effect.
Beta-glucan: contains two parts of macromolecules and micromolecules, wherein the macromolecules can stay on the surface of skin to form a film to lock the moisture of the skin, and the formed film can fill the wrinkle part of the skin and give people an illusion of 'instant wrinkle removal'. The small molecules can penetrate into the skin to promote the synthesis of procollagen, collagen and hyaluronic acid and the reconstruction of extracellular matrix.
Acetyl hexapeptide-8: can make the capsule not release the nerve conduction element effectively, thereby reducing facial expression contraction and achieving the effect of reducing wrinkles.
Carnosine: has strong antioxidant ability, and can scavenge Reactive Oxygen Species (ROS) and alpha-beta unsaturated aldehyde formed by excessive oxidation of fatty acid in cell membrane during oxidative stress.
Further, the paint comprises the following components in percentage by mass: 0.1-3% of tremella polysaccharide, 0.01-1.5% of hydrolyzed sodium hyaluronate, 1-15% of beta-glucan, 0.01-4% of acetyl hexapeptide-80.01%, 0.01-4% of carnosine and 72.5-98.87% of water.
Further, the paint comprises the following components in percentage by mass: 2% of tremella polysaccharide, 1% of hydrolyzed sodium hyaluronate, 13% of beta-glucan, 82% of acetyl hexapeptide, 2% of carnosine and 80% of water.
Further, the paint comprises the following components in percentage by mass: 0.8% of tremella polysaccharide, 0.8% of hydrolyzed sodium hyaluronate, 12% of beta-glucan, 81% of acetyl hexapeptide, 1% of carnosine and 84.4% of water.
The embodiment also provides a cosmetic, which comprises the composition with the anti-wrinkle effect and an auxiliary material, wherein the mass percent of the composition with the anti-wrinkle effect is 1.13-37%, and the mass percent of the auxiliary material is 63-98.87%.
Further, the auxiliary materials comprise any one or the combination of more than two of a surfactant, a thickening agent, an emulsifier, a humectant, a preservative, a pH regulator, a chelating agent, water, an emollient and an aromatic;
the humectant comprises any one or the combination of more than two of methyl propylene glycol, 1, 2-pentanediol, glycerol and propylene glycol;
the preservative comprises one or more of methyl ester, phenoxyethanol, ethylhexyl glycerol, methylparaben and ethylparaben;
the chelating agent comprises EDTA-2 NA;
the thickening agent comprises any one or the combination of more than two of carbomer and cetostearyl alcohol;
the pH regulator comprises triethanolamine;
the emulsifier comprises one or more of PEG-40 stearate, white beeswax and glyceryl stearate;
the emollient comprises any one or the combination of more than two of hydrogenated polyisobutene, hydrogenated vegetable oil, jojoba seed oil, white mineral oil, petrolatum and polydimethylsiloxane;
the aromatic is essence.
Further, the paint comprises the following components in percentage by mass: 0.01-2% of hydrolyzed sodium hyaluronate, 0.1-5% of tremella polysaccharide, 3-5% of methyl propylene glycol, 0.08-0.12% of methyl ester, 0.04-0.06% of EDTA-2NA, 0.8-1.2% of 1, 2-pentanediol, 0.2-0.6% of phenoxyethanol/ethylhexyl glycerol, 0.01-5% of carnosine, 0-80.01-5% of acetyl hexapeptide, 1-20% of beta-glucan and 63-98.87% of water.
Further, the paint comprises the following components in percentage by mass: 0.1-5% of tremella polysaccharide, 0.01-2% of hydrolyzed sodium hyaluronate, 0.1-0.3% of carbomer, 3-5% of methyl propylene glycol, 0.08-0.12% of methyl ester, 0.04-0.06% of EDTA-2NA, 0.1-0.3% of triethanolamine, 0.8-1.2% of 1, 2-pentanediol, 0.2-0.6% of phenoxyethanol/ethylhexyl glycerol, 1-20% of beta-glucan, 0.01-5% of acetyl hexapeptide-80.01, 0.01-5% of carnosine and 63-98.87% of water.
Further, the paint comprises the following components in percentage by mass: 2-3% of cetearyl alcohol, 2-3% of PEG-40 stearate, 0.8-1.2% of white beeswax, 0.8-1.2% of glyceryl stearate, 2-4% of hydrogenated polyisobutene, 0.8-1.2% of hydrogenated vegetable oil, 0.8-1.2% of jojoba seed oil, 4-6% of white mineral oil, 1-3% of petrolatum, 2-4% of polydimethylsiloxane, 0.04-0.06% of EDTA-2NA, 0.1-5% of tremella polysaccharide, 0.01-2% of sodium hyaluronate, 0.4-0.5% of carbomer, 4-6% of glycerol, 5-7% of methyl propylene glycol, 0.4-0.5% of triethanolamine, 0.7-0.9% of phenoxyethanol/methyl hydroxybenzoate/ethyl hydroxybenzoate/ethylhexylglycerol/propylene glycol, 0.1-0.3% of essence, 1-20% of beta-glucan, Acetyl hexapeptide-80.01-5%, carnosine 0.01-5%, and water 36-98.87%.
The embodiment also provides application of the cosmetic, and the cosmetic is applied to skin care.
Compared with the prior art, the invention has the following beneficial effects: the tremella polysaccharide in the composition can achieve the effect of quickly and long-acting wrinkle removal from outside to inside by the coordination of hydrolyzed sodium hyaluronate, beta-glucan, acetyl hexapeptide-8, carnosine and the like, wherein a breathable protective film is formed on the surface of skin by macromolecules in the beta-glucan in the composition, and the phenomenon of instant wrinkle removal is caused after the 'ravines' of wrinkles are filled. And then, the super-strong moisturizing capability of the hydrolyzed sodium hyaluronate is utilized to replenish water and lock water for the skin, provide nutrition for the horny layer and restore the tenderness and elasticity of the skin. The acetyl hexapeptide-8 has less facial muscle contraction for a long time, reduces the damage of elastic fibers and ensures the effective elasticity of the skin. The tremella polysaccharide can effectively shield the skin from being damaged by the external environment while improving the immunity of the human body. Carnosine eliminates fatty acid over-oxidation of cell membranes and restores cell viability. The invention combines the multi-dimensional internal and external consideration with the long-acting effect in time, thereby achieving the excellent effect of synergy.
Detailed Description
The invention is further described with reference to the following examples.
The embodiment provides a composition with an anti-wrinkle effect, which comprises the following components in percentage by mass: 0.1-5% of tremella polysaccharide, 0.01-2% of hydrolyzed sodium hyaluronate, 1-20% of beta-glucan, 0.01-5% of acetyl hexapeptide-80.01%, 0.01-5% of carnosine and 63-98.87% of water.
White fungus polysaccharide: aiming at an immune defense system, the immunity of body fluid is improved, the phagocytic capacity of phagocytes is enhanced, the growth of cell factors is promoted, and the erythrocyte membrane is protected from being easily damaged by oxidation. Thereby improving the autoimmune capability of the human body and enhancing the resistance of the human body to diseases. Besides the effect of improving the immunity of the organism, the tremella polysaccharide can promote the synthesis of protein and nucleic acid and increase the self-repairing capacity;
hydrolysis of sodium hyaluronate: has a small molecular weight, can permeate into the stratum corneum and then provide nutrition, and has excellent moisturizing effect. The skin moisturizing cream can provide lasting moisture for the skin, firmly lock water in the body and enable the skin to be full, soft and bright;
beta-glucan: the skin wrinkle removing mask contains two parts of macromolecules and micromolecules, the macromolecules can stay on the surface of skin to form a film to lock skin moisture, and the formed film can fill the wrinkle part of the skin and provide an illusion of 'instant wrinkle removal'. The small molecules can penetrate into the skin to promote the synthesis of procollagen, collagen and hyaluronic acid and the reconstruction of extracellular matrix;
acetyl hexapeptide-8: the capsule can not effectively release the neurotransmitters, so that facial expression contraction is reduced, and the effect of reducing wrinkles is achieved;
carnosine: has strong antioxidant ability, and can scavenge Reactive Oxygen Species (ROS) and alpha-beta unsaturated aldehyde formed by excessive oxidation of fatty acid in cell membrane during oxidative stress.
In a preferred embodiment, the composition comprises the following components in percentage by mass: 0.1-3% of tremella polysaccharide, 0.01-1.5% of hydrolyzed sodium hyaluronate, 1-15% of beta-glucan, 0.01-4% of acetyl hexapeptide-80.01%, 0.01-4% of carnosine and 72.5-98.87% of water.
In a preferred embodiment, the composition comprises the following components in percentage by mass: 2% of tremella polysaccharide, 1% of hydrolyzed sodium hyaluronate, 13% of beta-glucan, 82% of acetyl hexapeptide, 2% of carnosine and 80% of water.
In a preferred embodiment, the composition comprises the following components in percentage by mass: 0.8% of tremella polysaccharide, 0.8% of hydrolyzed sodium hyaluronate, 12% of beta-glucan, 81% of acetyl hexapeptide, 1% of carnosine and 84.4% of water.
The embodiment also provides a cosmetic, which comprises the composition with the anti-wrinkle effect and an auxiliary material, wherein the sum of the mass percentages of the components in the cosmetic is 100%.
In a preferred embodiment, the composition with the anti-wrinkle effect accounts for 1.13-37% by mass, and the auxiliary materials account for 63-98.87% by mass.
In a preferred embodiment, the auxiliary materials comprise any one or a combination of more than two of a surfactant, a thickening agent, an emulsifier, a humectant, a preservative, a pH regulator, a chelating agent, water, an emollient and an aromatic;
the humectant comprises any one or the combination of more than two of methyl propylene glycol, 1, 2-pentanediol, glycerol and propylene glycol;
the preservative comprises one or more of methyl ester, phenoxyethanol, ethylhexyl glycerol, methylparaben and ethylparaben;
the chelating agent comprises EDTA-2 NA;
the thickening agent comprises any one or the combination of more than two of carbomer and cetostearyl alcohol;
the pH regulator comprises triethanolamine;
the emulsifier comprises one or more of PEG-40 stearate, white beeswax and glyceryl stearate;
the emollient comprises any one or the combination of more than two of hydrogenated polyisobutene, hydrogenated vegetable oil, jojoba seed oil, white mineral oil, petrolatum and polydimethylsiloxane;
the aromatic is essence.
In a preferred embodiment, the composition comprises the following components in percentage by mass: 0.01-2% of hydrolyzed sodium hyaluronate, 0.1-5% of tremella polysaccharide, 3-5% of methyl propylene glycol, 0.08-0.12% of methyl ester, 0.04-0.06% of EDTA-2NA, 0.8-1.2% of 1, 2-pentanediol, 0.2-0.6% of phenoxyethanol/ethylhexyl glycerol, 0.01-5% of carnosine, 0-80.01-5% of acetyl hexapeptide, 1-20% of beta-glucan and 63-98.87% of water.
In a preferred embodiment, the composition comprises the following components in percentage by mass: 0.1-5% of tremella polysaccharide, 0.01-2% of hydrolyzed sodium hyaluronate, 0.1-0.3% of carbomer, 3-5% of methyl propylene glycol, 0.08-0.12% of methyl ester, 0.04-0.06% of EDTA-2NA, 0.1-0.3% of triethanolamine, 0.8-1.2% of 1, 2-pentanediol, 0.2-0.6% of phenoxyethanol/ethylhexyl glycerol, 1-20% of beta-glucan, 0.01-5% of acetyl hexapeptide-80.01, 0.01-5% of carnosine and 63-98.87% of water.
In a preferred embodiment, the composition comprises the following components in percentage by mass: 2-3% of cetearyl alcohol, 2-3% of PEG-40 stearate, 0.8-1.2% of white beeswax, 0.8-1.2% of glyceryl stearate, 2-4% of hydrogenated polyisobutene, 0.8-1.2% of hydrogenated vegetable oil, 0.8-1.2% of jojoba seed oil, 4-6% of white mineral oil, 1-3% of petrolatum, 2-4% of polydimethylsiloxane, 0.04-0.06% of EDTA-2NA, 0.1-5% of tremella polysaccharide, 0.01-2% of sodium hyaluronate, 0.4-0.5% of carbomer, 4-6% of glycerol, 5-7% of methyl propylene glycol, 0.4-0.5% of triethanolamine, 0.7-0.9% of phenoxyethanol/methyl hydroxybenzoate/ethyl hydroxybenzoate/ethylhexylglycerol/propylene glycol, 0.1-0.3% of essence, 1-20% of beta-glucan, Acetyl hexapeptide-80.01-5%, carnosine 0.01-5%, and water 36-98.87%.
The embodiment also provides application of the cosmetic, and the cosmetic is applied to skin care, wherein the cosmetic comprises lotion, essence, skin care emulsion, skin moistening cream, facial cleanser, facial mask, skin care gel and the like, and the aim of slowing down to remove fine lines of skin and fishtail lines around eyes can be fulfilled.
The invention will be further illustrated with reference to specific examples:
example 1:
a cosmetic is a repairing stock solution and comprises the following components in parts by weight: 0.1% of hydrolyzed sodium hyaluronate, 0.1% of tremella polysaccharide, 4% of methyl propylene glycol, 0.1% of methyl ester, 0.05% of EDTA-2NA, 1% of 1, 2-pentanediol, 0.4% of phenoxyethanol/ethylhexyl glycerol, 1% of carnosine, 83% of acetyl hexapeptide, 20% of beta-glucan and 70.25% of water.
The preparation method comprises the following steps:
the method comprises the following steps: adding 70.25% of water, 0.1% of hydrolyzed sodium hyaluronate, 0.1% of tremella polysaccharide, 4% of methyl propylene glycol, 0.1% of methyl ester and 0.05% of EDTA-2NA into an emulsifying pot, stirring and heating to 85 ℃, and preserving heat for 30 minutes for later use;
step two: after the emulsification pot is kept warm for 30 minutes in the first step, continuously stirring and cooling to 60 ℃, uniformly mixing 1, 2-pentanediol 1% and 0.4% of phenoxyethanol/ethylhexyl glycerin, adding into the emulsification pot, continuously stirring and cooling to 45 ℃ for later use;
step three: and (3) adding 1% of carnosine, 83-83% of acetyl hexapeptide and 20% of beta-glucan into the emulsifying pot in the second step, continuing stirring and cooling to 38 ℃, sampling, detecting, filtering and discharging after the carnosine, the acetyl hexapeptide and the beta-glucan are qualified, and thus preparing the repairing stock solution.
Example 2
A cosmetic is a repair essence and comprises the following components in parts by weight: 0.2% of tremella polysaccharide, 0.2% of hydrolyzed sodium hyaluronate, 0.2% of carbomer, 4% of methyl propylene glycol, 0.1% of methyl ester, 0.05% of EDTA-2NA, 0.2% of triethanolamine, 1, 2-pentanediol, 0.4% of phenoxyethanol/ethylhexyl glycerol, 15% of beta-glucan, 83-acetyl hexapeptide, 1% of carnosine and 74.65% of water.
The preparation method comprises the following steps:
the method comprises the following steps: adding 74.65% of water, 0.2% of tremella polysaccharide, 0.2% of hydrolyzed sodium hyaluronate, 0.2% of carbomer, 4% of methyl propylene glycol, 0.1% of methyl ester and 0.05% of EDTA-2NA into an emulsifying pot, stirring and heating to 85 ℃, and keeping the temperature for 30 minutes for later use;
step two: after the emulsification pot is kept warm for 30 minutes in the first step, continuously stirring and cooling to 60 ℃, taking 0.2 percent of triethanolamine, adding the triethanolamine into the emulsification pot, and continuously stirring and cooling to 45 ℃ for later use;
step three: uniformly mixing 1, 2-pentanediol 1% and phenoxyethanol/ethylhexyl glycerin 0.4%, adding into the emulsifying pot in the second step, and continuously stirring and cooling to 45 ℃ for later use;
step four: adding 15% of beta-glucan, 83-acetyl hexapeptide and 1% of carnosine into an emulsifying pot in the third step, continuously stirring and cooling to 38 ℃, sampling and detecting, filtering and discharging after the beta-glucan is qualified, and thus obtaining the repair essence.
Example 3
A cosmetic is a repairing emulsion and comprises the following components in parts by weight: 2.5% of cetearyl alcohol, 2.5% of PEG-40 stearate, 1% of white beeswax, 1% of glyceryl stearate, 3% of hydrogenated polyisobutene, 1% of hydrogenated vegetable oil, 1% of jojoba seed oil, 5% of white mineral oil, 2% of petrolatum, 3% of polydimethylsiloxane, 0.05% of EDTA-2NA, 0.1% of tremella polysaccharide, 0.1% of hydrolyzed sodium hyaluronate, 0.45% of carbomer, 5% of glycerol, 6% of methyl propylene glycol, 0.45% of triethanolamine, 0.8% of phenoxyethanol/methylparaben/ethylparaben/ethylhexylglycerol/propylene glycol, 0.2% of essence, 20% of beta-glucan, 85% of acetyl hexapeptide, 3% of carnosine, and 36.85% of water.
The preparation method comprises the following steps:
the method comprises the following steps: taking 2.5% of cetearyl alcohol, 2.5% of PEG-40 stearate, 1% of white beeswax, 1% of glyceryl stearate, 3% of hydrogenated polyisobutene, 1% of hydrogenated vegetable oil, 1% of jojoba seed oil, 5% of white mineral oil, 2% of petrolatum and 3% of polydimethylsiloxane, uniformly stirring, adding into an oil phase pot, heating to 85 ℃, and preserving heat for 10 minutes for later use;
step two: taking 36.85% of water, 0.05% of EDTA-2NA, 0.1% of tremella polysaccharide, 0.1% of hydrolyzed sodium hyaluronate, 0.45% of carbomer, 5% of glycerol and 6% of methyl propylene glycol, uniformly stirring, adding the mixture into a water phase pot, heating to 85 ℃, and keeping the temperature for 15 minutes for later use;
step three: pumping the mixture in the water phase pot in the step two into an emulsifying pot, pumping the mixture in the oil phase pot in the step one into the emulsifying pot, homogenizing for 5 minutes, starting the emulsifying pot, cooling to 60 ℃ for later use;
step four: adding 0.45% of triethanolamine into an emulsifying pot in the third step, mixing and stirring uniformly, and cooling to 45 ℃ for later use;
step five: adding 0.8% of phenoxyethanol/methylparaben/ethylparaben/ethylhexyl glycerol/propylene glycol, 0.2% of essence, 20% of beta-glucan, 85% of acetyl hexapeptide and 3% of carnosine into an emulsifying pot in the fourth step, continuously stirring and cooling to 38 ℃, sampling and detecting, filtering and discharging after the materials are qualified, and thus obtaining the repairing emulsion.
Examples of the experiments
Firstly, safety testing.
Subject: 50 people in total, half of men and women, age 22-55 years.
Experimental mode: the cosmetics prepared in examples 1 to 3 were tested for patches; selecting a qualified spot tester, placing about 0.02-0.025 ml of a tested object into the spot tester by a closed spot test method, externally applying a medical adhesive tape to the back of the tested object, removing the tested object after 24 hours, observing skin reactions 0.5, 24 and 48 hours after the spot is removed, and recording the results according to the skin reaction standard in technical Specification for cosmetic safety (2015 edition).
And (4) experimental conclusion: the experimental evaluation criteria are shown in table one below:
TABLE-SKIN ADVERSE RATION STANDARD
As can be seen from the table I, the result of the human skin blocking patch test shows that no positive reaction occurs in the subject. The test substance did not cause adverse skin reactions to the subjects of this batch as specified in the technical Specification for cosmetic safety (2015 edition), so the cosmetics in examples 1-3 were in compliance with the test regulations.
And secondly, skin repair evaluation and detection.
A detection instrument: a camera.
The detection principle is as follows: the volunteers need plain color photographs for archiving before receiving the test, take photographs for archiving after using the product for 30 minutes, take photographs for archiving after using plain color for 30 days, and take photographs for archiving after continuing to use the placebo for 3 days.
Detecting an object: healthy volunteers aged 18-50 years without skin diseases and allergic history were selected as test subjects, the number of the volunteers was 30, and 15 men and women were each.
Detection conditions are as follows: the room temperature is below 20 plus or minus 2 ℃, and the relative humidity (R H) is below 50 plus or minus 5 percent; the tested person enters the testing environment 30min before the test for quiet test, and the tested part is exposed 10min before the test.
The detection method comprises the following steps: the volunteers were divided into 3 groups of 10 persons each, and the anti-aging and repairing effects of the stock solution, essence, and emulsion in examples 1 to 3 were tested, respectively. Before testing, all three volunteers had to remove makeup and take pictures in the plain state with a VISA facial image analyzer. The face of each volunteer group was photographed in plain by VISA for 30 days of constant use, compared to the first photograph.
And (3) detection results: the test evaluation criteria are shown in table two below:
TABLE 2 comparison of facial pictures before and after use by volunteers
As can be seen from table 2, the combination with anti-wrinkle effect and its effect in cosmetic applications in the formulations of examples 1-3. After the anti-wrinkle fabric is used for 30 minutes, wrinkles are obviously improved, and the effect of removing wrinkles instantly is achieved; after 30 days of use, the synergistic effect is achieved through multi-dimensional synergistic conditioning in the anti-wrinkle composition. The wrinkle removing ability, the moisture retention and the elasticity of the skin are obviously improved at the moment, which indicates that the wrinkles are controlled and relieved; the data after the use for 3 days indicate that the wrinkle removing effect is really improved from inside to outside, and the excellent effects of quickness, effectiveness and durability are really achieved.
Compared with the prior art, the invention has the following beneficial effects: the tremella polysaccharide in the composition can achieve the effect of quickly and long-acting wrinkle removal from outside to inside by the coordination of hydrolyzed sodium hyaluronate, beta-glucan, acetyl hexapeptide-8, carnosine and the like, wherein a breathable protective film is formed on the surface of skin by macromolecules in the beta-glucan in the composition, and the phenomenon of instant wrinkle removal is caused after the 'ravines' of wrinkles are filled. And then, the super-strong moisturizing capability of the hydrolyzed sodium hyaluronate is utilized to replenish water and lock water for the skin, provide nutrition for the horny layer and restore the tenderness and elasticity of the skin. The acetyl hexapeptide-8 has less facial muscle contraction for a long time, reduces the damage of elastic fibers and ensures the effective elasticity of the skin. The tremella polysaccharide can effectively shield the skin from being damaged by the external environment while improving the immunity of the human body. Carnosine eliminates fatty acid over-oxidation of cell membranes and restores cell viability. The invention combines the multi-dimensional internal and external consideration with the long-acting effect in time, thereby achieving the excellent effect of synergy.
Finally, it should be noted that the above embodiments are only used for illustrating the technical solutions of the present invention, and not for limiting the protection scope of the present invention, although the present invention is described in detail with reference to the preferred embodiments, it should be understood by those skilled in the art that modifications or equivalent substitutions can be made on the technical solutions of the present invention without departing from the spirit and scope of the technical solutions of the present invention.
Claims (10)
1. A composition with anti-wrinkle effect is characterized in that: the composite material comprises the following components in percentage by mass: 0.1-5% of tremella polysaccharide, 0.01-2% of hydrolyzed sodium hyaluronate, 1-20% of beta-glucan, 0.01-5% of acetyl hexapeptide-80.01%, 0.01-5% of carnosine and 63-98.87% of water.
2. The composition with anti-wrinkle effect according to claim 1, wherein: the composite material comprises the following components in percentage by mass: 0.1-3% of tremella polysaccharide, 0.01-1.5% of hydrolyzed sodium hyaluronate, 1-15% of beta-glucan, 0.01-4% of acetyl hexapeptide-80.01%, 0.01-4% of carnosine and 72.5-98.87% of water.
3. The composition with anti-wrinkle effect according to claim 1, wherein: the composite material comprises the following components in percentage by mass: 2% of tremella polysaccharide, 1% of hydrolyzed sodium hyaluronate, 13% of beta-glucan, 82% of acetyl hexapeptide, 2% of carnosine and 80% of water.
4. The composition with anti-wrinkle effect according to claim 1, wherein: the composite material comprises the following components in percentage by mass: 0.8% of tremella polysaccharide, 0.8% of hydrolyzed sodium hyaluronate, 12% of beta-glucan, 81% of acetyl hexapeptide, 1% of carnosine and 84.4% of water.
5. A cosmetic characterized by: the composition with the anti-wrinkle effect comprises the composition with the anti-wrinkle effect of any one of claims 1 to 4 and an auxiliary material, wherein the mass percent of the composition with the anti-wrinkle effect is 1.13-37%, and the mass percent of the auxiliary material is 63-98.87%.
6. The cosmetic composition of claim 5, wherein: the auxiliary materials comprise any one or the combination of more than two of a surfactant, a thickening agent, an emulsifier, a humectant, a preservative, a pH regulator, a chelating agent, water, an emollient and an aromatic;
the humectant comprises any one or the combination of more than two of methyl propylene glycol, 1, 2-pentanediol, glycerol and propylene glycol;
the preservative comprises one or more of methyl ester, phenoxyethanol, ethylhexyl glycerol, methylparaben and ethylparaben;
the chelating agent comprises EDTA-2 NA;
the thickening agent comprises any one or the combination of more than two of carbomer and cetostearyl alcohol;
the pH regulator comprises triethanolamine;
the emulsifier comprises one or more of PEG-40 stearate, white beeswax and glyceryl stearate;
the emollient comprises any one or the combination of more than two of hydrogenated polyisobutene, hydrogenated vegetable oil, jojoba seed oil, white mineral oil, petrolatum and polydimethylsiloxane;
the aromatic is essence.
7. The cosmetic composition of claim 6, wherein: the composite material comprises the following components in percentage by mass: 0.01-2% of hydrolyzed sodium hyaluronate, 0.1-5% of tremella polysaccharide, 3-5% of methyl propylene glycol, 0.08-0.12% of methyl ester, 0.04-0.06% of EDTA-2NA, 0.8-1.2% of 1, 2-pentanediol, 0.2-0.6% of phenoxyethanol/ethylhexyl glycerol, 0.01-5% of carnosine, 0-80.01-5% of acetyl hexapeptide, 1-20% of beta-glucan and 63-98.87% of water.
8. The cosmetic composition of claim 6, wherein: the composite material comprises the following components in percentage by mass: 0.1-5% of tremella polysaccharide, 0.01-2% of hydrolyzed sodium hyaluronate, 0.1-0.3% of carbomer, 3-5% of methyl propylene glycol, 0.08-0.12% of methyl ester, 0.04-0.06% of EDTA-2NA, 0.1-0.3% of triethanolamine, 0.8-1.2% of 1, 2-pentanediol, 0.2-0.6% of phenoxyethanol/ethylhexyl glycerol, 1-20% of beta-glucan, 0.01-5% of acetyl hexapeptide-80.01, 0.01-5% of carnosine and 63-98.87% of water.
9. The cosmetic composition of claim 6, wherein: the composite material comprises the following components in percentage by mass: 2-3% of cetearyl alcohol, 2-3% of PEG-40 stearate, 0.8-1.2% of white beeswax, 0.8-1.2% of glyceryl stearate, 2-4% of hydrogenated polyisobutene, 0.8-1.2% of hydrogenated vegetable oil, 0.8-1.2% of jojoba seed oil, 4-6% of white mineral oil, 1-3% of petrolatum, 2-4% of polydimethylsiloxane, 0.04-0.06% of EDTA-2NA, 0.1-5% of tremella polysaccharide, 0.01-2% of sodium hyaluronate, 0.4-0.5% of carbomer, 4-6% of glycerol, 5-7% of methyl propylene glycol, 0.4-0.5% of triethanolamine, 0.7-0.9% of phenoxyethanol/methyl hydroxybenzoate/ethyl hydroxybenzoate/ethylhexylglycerol/propylene glycol, 0.1-0.3% of essence, 1-20% of beta-glucan, Acetyl hexapeptide-80.01-5%, carnosine 0.01-5%, and water 36-98.87%.
10. Use of a cosmetic product according to any one of claims 5 to 9, characterized in that: applying the cosmetic to skin care.
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