CN111568797A - Composition for quickly removing fine lines and application thereof - Google Patents

Composition for quickly removing fine lines and application thereof Download PDF

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Publication number
CN111568797A
CN111568797A CN202010359535.3A CN202010359535A CN111568797A CN 111568797 A CN111568797 A CN 111568797A CN 202010359535 A CN202010359535 A CN 202010359535A CN 111568797 A CN111568797 A CN 111568797A
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raw material
dimethicone
cosmetic
glycerol
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殷岩岩
张娇
韩志东
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Quanhou Guangzhou Research Institute Of Biotechnology Co ltd
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Quanhou Guangzhou Research Institute Of Biotechnology Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • A61K8/602Glycosides, e.g. rutin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A61K8/442Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof substituted by amido group(s)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4913Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/89Polysiloxanes
    • A61K8/891Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/005Preparations for sensitive skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18

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  • Biotechnology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Cosmetics (AREA)

Abstract

The invention discloses a composition for quickly removing fine lines and application thereof, wherein the composition is glycerol glucoside, polydimethylsiloxane/vinyl polydimethylsiloxane cross-linked polymer, dipeptide diaminobutyrylbenzylamide diacetate, acetyl hexapeptide-8, a composite humectant, a red ginseng extract and soluble proteoglycan, and can be used for preparing various anti-aging products such as essence, gel, eye cream, face cream, neck cream and the like; the composition disclosed by the invention is simple in preparation method, fine lines can be faded in three minutes, the fine line removing effect is quick, no side effect is caused, and a safe and effective fine line removing option is provided for consumers.

Description

Composition for quickly removing fine lines and application thereof
Technical Field
The invention belongs to the field of daily chemicals, and relates to a composition for quickly removing fine lines and application thereof.
Background
The biggest natural enemy of female beauty is that the skin appears with a plurality of aging manifestations with the most important manifestation being the increase of skin wrinkles along with the increase of age. Lines are the initial signs of skin aging, and wrinkles develop further, forming folds, i.e., deeper folds in the skin.
The fine lines are like wrinkles in medicine, and refer to the linear textures presented on the physiological aging of human skin and the long-term contraction of eye muscles, and the generation of the fine lines is greatly accelerated by the physiological aging of the skin and the long-term contraction of the eye muscles and the long-term dryness and water shortage. Among them, the skin around the eyes lacks sebaceous glands, is easily dried, and is affected by the external environment to form free radicals, and the free radicals destroy collagen and active substances in normal cell membrane tissues, so that the skin is the part most easily with fine wrinkles.
The existing common method for removing fine lines comprises hot and cold water eye applying and soft massage, so that eye circulation can be smoother, and nutrients can be better absorbed; some products aiming at eye fine lines are also available in the market, but most products have poor or unobvious effects; the fastest method is to inject a botulinum toxin needle, but the method is not only expensive, but also has certain risks, and cannot meet the requirements of most consumers.
Disclosure of Invention
The invention aims to provide a fine grain removing composition with remarkable effect and no side effect aiming at the defects of the prior art.
In order to achieve the purpose, the invention adopts the technical scheme that: a composition for reducing striae, said composition comprising glyceryl glucoside, dimethicone/vinyl dimethicone crosspolymer, dipeptide diaminobutyrylbenzylamide diacetate, acetyl hexapeptide-8, complex humectant, red ginseng extract, and soluble proteoglycan; the compound humectant comprises the following components in percentage by mass: 26.87% betaine, 9.75% sodium PCA, 3.78% pyrrolidone carboxylic acid, 5% calcium lactate, 1.12% serine, 1.06% alanine, 1% glycine, 0.43% glutamic acid, 0.34% lysine HCl, 0.32% threonine, 0.29% arginine, 0.04% proline, 25% trehalose and 25% water.
The glycerol glucoside has excellent moisturizing capability and good skin permeability, and can effectively reduce water loss; the polydimethylsiloxane/vinyl polydimethylsiloxane crosslinked polymer is safer in component, has no stimulation to skin and mucous membrane, and can endow the product with silky feeling; the dipeptide diaminobutyrylbenzylamide diacetate is a small peptide simulating the activity of snake venom toxin WaglerinI, and clinical tests show that the snake venom peptide can reduce the generation of wrinkles by inhibiting muscle contraction and has excellent smooth and rapid wrinkle removing performance; acetyl hexapeptide-8 participates in competition of SNAP-25 at the site of the vacuolar complex, so that the formation of the complex is influenced, and when the vacuolar complex is slightly unstable, the vacuolar complex cannot effectively release neurotransmitters, so that the contraction of muscles is weakened, and the formation of wrinkles is prevented; the compound humectant is a compound formed by a plurality of amino acids, betaine, PCA sodium and other components, has good moisturizing performance, small molecules in the compound humectant can quickly permeate into horny layer to supplement moisturizing factors among horny cells, so that the interweaving is full, and fine wrinkles are reduced; the red ginseng extract contains various ginsenoside and polysaccharide components, has the function of extending and growing the vascular endothelial cells and protecting the existing blood vessels, and researches show that the red ginseng extract has the anti-aging function, the polysaccharide component can form a protective film on the surface of the skin to prevent water from volatilizing, and the saponin component can increase the generation of collagen and smooth wrinkles after long-term use; the soluble proteoglycan is from deep sea, is a main extracellular tissue component, integrates the advantages of oligopeptide and hyaluronic acid, has the effects of strong moisture retention and strong repair, has the cell activation effect, can accelerate the renewal and metabolism of skin, stimulates the generation of hyaluronic acid and collagen, maintains the skin moistening state and improves skin wrinkles.
The invention has the advantages that various components are mutually matched, and the effect of removing the fine lines in a synergistic manner is realized by starting from various angles.
As a preferred embodiment of the anti-stringiness composition of the present invention, the anti-stringiness composition comprises the following components in parts by weight: 1 to 2.5 parts of glycerol glucoside, 0.4 to 1.2 parts of polydimethylsiloxane/vinyl polydimethylsiloxane cross-linked polymer, 0.001 to 0.003 part of dipeptide diaminobutyrylbenzyl amide diacetate, 0.78 to 0.003 part of acetyl hexapeptide-80.00125, 0.5 to 4 parts of compound humectant, 0.05 to 0.5 part of red ginseng extract and 0.002 to 0.01 part of soluble proteoglycan. The components can achieve a good fine grain removing effect within the range of the mixture ratio.
As a more preferred embodiment of the anti-stringiness composition of the present invention, the anti-stringiness composition comprises the following components in parts by weight: 1.8 parts of glycerol glucoside, 0.8 part of polydimethylsiloxane/vinyl polydimethylsiloxane cross-linked polymer, 0.0125 part of dipeptide diaminobutyrylbenzylamide diacetate, 2 parts of acetyl hexapeptide-80.0015 parts of compound humectant, 0.2 part of red ginseng extract and 0.005 part of soluble proteoglycan. The fine grain removing effect of each component is optimal particularly under the proportion.
The invention also claims the application of the composition in preparing anti-aging cosmetics.
As a preferred embodiment of the present invention, the cosmetic comprises essence, gel, eye cream, face cream, neck cream.
The invention also claims an anti-aging cosmetic comprising the composition.
The invention comprises the following components in percentage by mass: 1 to 2.5% of glycerol glucoside, 0.4 to 1.2% of polydimethylsiloxane/vinyl polydimethylsiloxane cross-linked polymer, 0.001 to 0.003% of dipeptide diaminobutyrylbenzylamide diacetate, 0.00125 to 0.003% of acetyl hexapeptide-8, 0.5 to 4% of a complex humectant, 0.05 to 0.5% of red ginseng extract, and 0.002 to 0.01% of soluble proteoglycan.
More preferably, the anti-aging cosmetic comprises the following components in percentage by mass: 1.8% glycerol glucoside, 0.8% dimethicone/vinyl dimethicone crosspolymer, 0.0125% dipeptide diaminobutyrylbenzylamide diacetate, 0.0015% acetyl hexapeptide-8, 2% complex humectant, 0.2% red ginseng extract, and 0.005% soluble proteoglycan.
As a preferred embodiment of the invention, the composition also comprises the following components in percentage by mass: 0.5-2% of shea butter, 1-4% of triisocaprylic glyceride, 1-3% of polydimethylsiloxane, 0.1-0.5% of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, 0.1-0.5% of sodium acrylate/sodium acryloyldimethyl taurate copolymer, 0.5-2% of PEG-100 stearate, 0.5-2% of glycerol stearate, 5-10% of glycerol, 0.02-0.1% of EDTA disodium and 0.02-0.1% of sodium hydroxide.
As a preferred embodiment of the invention, the composition also comprises the following components in percentage by mass: 0.01-0.06% of essence and 0.2-15% of preservative.
As a preferred embodiment of the invention, the cosmetic comprises the following components in percentage by mass: 1.8% glycerol glucoside, 0.8% dimethicone/vinyl dimethicone crosspolymer, 0.0125% dipeptide diaminobutyrylbenzylamide diacetate, 0.0015% acetyl hexapeptide-8, 2% complex humectant, 0.2% red ginseng extract, 0.005% soluble proteoglycan, 1% shea butter, 3% glyceryl triisooctanoate, 2% dimethicone, 0.25% acrylic acid/C10-30 alkanol acrylate crosspolymer, 0.3% sodium acrylate/sodium acryloyldimethyl taurate copolymer, 0.6% PEG-100 stearate, 0.6% glyceryl stearate, 7.5% glycerol, 0.02% disodium EDTA, 0.0425% sodium hydroxide, 0.5% preservative, 0.025% perfume and the balance deionized water.
The invention also provides a preparation method of the cosmetic, which comprises the following steps:
(1) putting the phase A raw material into a water phase pot, stirring and heating to 75-80 ℃, homogenizing for 5min, and then keeping the temperature and stirring until the raw material is uniformly dispersed;
(2) putting the phase B raw material into an oil phase pot, stirring and heating to 77-82 ℃, and stirring until the phase B raw material is completely melted;
(3) pumping the mixture obtained in the steps (1) and (2) into an emulsifying pot through 100-mesh filter cloth, homogenizing for 10min, and continuing to keep the temperature and stir for 5 min;
(4) cooling the mixture in the step (3) to 60 ℃, dissolving the C-phase raw material with a proper amount of pure water, adding the dissolved C-phase raw material into an emulsifying pot, homogenizing for 5min, and stirring until the material body is uniform;
(5) cooling the mixture in the step (4) to 40 ℃, adding the D-phase, E-phase and F-phase raw materials one by one, and stirring the mixture uniformly;
(6) cooling the mixture obtained in the step (5) to 35 ℃, and discharging after the mixture is qualified through inspection;
wherein the phase A raw material comprises: glycerol, glycerol glucoside, acrylic acid/C10-30 alkanol acrylate crosspolymer, sodium acrylate/sodium acryloyldimethyl taurate copolymer and disodium EDTA;
the phase B raw material comprises: dimethicone/vinyl dimethicone crosspolymer, PEG-100 stearate, shea butter, glyceryl triisooctanoate, dimethicone, and glyceryl stearate;
the C phase raw material comprises potassium hydroxide;
the phase D raw material comprises a compound humectant;
the phase E material comprises a preservative;
the F phase raw material comprises essence.
In a preferred embodiment of the present invention, the pure water added in the step (4) is 2% by mass of the cosmetic.
The invention provides a composition capable of quickly removing fine lines, which can be used for preparing anti-aging products such as essence, gel, eye cream, face cream, neck cream and the like; the composition disclosed by the invention is simple in preparation method, fine lines can be faded in three minutes, the fine line removing effect is quick, no side effect is caused, and a safe and effective fine line removing option is provided for consumers.
Detailed Description
To better illustrate the objects, aspects and advantages of the present invention, the present invention will be further described with reference to specific examples.
Example 1
The invention relates to an embodiment of an anti-aging cosmetic, which comprises the following components in percentage by mass: 1.8% glycerol glucoside, 0.8% dimethicone/vinyl dimethicone crosspolymer, 0.0125% dipeptide diaminobutyrylbenzylamide diacetate, 0.0015% acetyl hexapeptide-8, 2% complex humectant, 0.2% red ginseng extract, 0.005% soluble proteoglycan, 1% shea butter, 3% glyceryl triisooctanoate, 2% dimethicone, 0.25% acrylic acid/C10-30 alkanol acrylate crosspolymer, 0.3% sodium acrylate/sodium acryloyldimethyl taurate copolymer, 0.6% PEG-100 stearate, 0.6% glycerol stearate, 7.5% glycerol, 0.02% disodium EDTA, 0.0425% sodium hydroxide, 0.5% preservative, 0.025% perfume and the balance deionized water; the compound humectant comprises the following components in percentage by mass: 26.87% betaine, 9.75% sodium PCA, 3.78% pyrrolidone carboxylic acid, 5% calcium lactate, 1.12% serine, 1.06% alanine, 1% glycine, 0.43% glutamic acid, 0.34% lysine HCl, 0.32% threonine, 0.29% arginine, 0.04% proline, 25% trehalose, and 25% water; the compound humectant comprises the following components in percentage by mass: 26.87% betaine, 9.75% sodium PCA, 3.78% pyrrolidone carboxylic acid, 5% calcium lactate, 1.12% serine, 1.06% alanine, 1% glycine, 0.43% glutamic acid, 0.34% lysine HCl, 0.32% threonine, 0.29% arginine, 0.04% proline, 25% trehalose and 25% water.
The preparation method of the cosmetic comprises the following steps:
(1) putting the phase A raw material into a water phase pot, stirring and heating to 75-80 ℃, homogenizing for 5min, and then keeping the temperature and stirring until the raw material is uniformly dispersed;
(2) putting the phase B raw material into an oil phase pot, stirring and heating to 77-82 ℃, and stirring until the phase B raw material is completely melted;
(3) pumping the mixture obtained in the steps (1) and (2) into an emulsifying pot through 100-mesh filter cloth, homogenizing for 10min, and continuing to keep the temperature and stir for 5 min;
(4) cooling the mixture in the step (3) to 60 ℃, dissolving the C-phase raw material in pure water with the mass percentage of 2%, adding the dissolved C-phase raw material into an emulsifying pot, homogenizing for 5min, and stirring until the material body is uniform;
(5) cooling the mixture in the step (4) to 40 ℃, adding the D-phase, E-phase and F-phase raw materials one by one, and stirring the mixture uniformly;
(6) cooling the mixture obtained in the step (5) to 35 ℃, and discharging after the mixture is qualified through inspection;
wherein the phase A raw material comprises: glycerol, glycerol glucoside, acrylic acid/C10-30 alkanol acrylate crosspolymer, sodium acrylate/sodium acryloyldimethyl taurate copolymer and disodium EDTA;
the phase B raw material comprises: dimethicone/vinyl dimethicone crosspolymer, PEG-100 stearate, shea butter, glyceryl triisooctanoate, dimethicone, and glyceryl stearate;
the C phase raw material comprises potassium hydroxide;
the phase D raw material comprises a compound humectant;
the phase E material comprises a preservative;
the F phase raw material comprises essence.
Example 2
The invention discloses an embodiment of an anti-aging cosmetic, which is the same as the embodiment 1 except that the cosmetic comprises the following components in percentage by mass: 2.5% glycerol glucoside, 1.2% dimethicone/vinyl dimethicone crosspolymer, 0.003% dipeptide diaminobutyrylbenzylamide diacetate, 0.003% acetyl hexapeptide-8, 4% complex humectant, 0.5% red ginseng extract, 0.01% soluble proteoglycan.
Example 3
The invention discloses an embodiment of an anti-aging cosmetic, which is the same as the embodiment 1 except that the cosmetic comprises the following components in percentage by mass: 1.0% glycerol glucoside, 0.4% dimethicone/vinyl dimethicone crosspolymer, 0.001% dipeptide diaminobutyrylbenzylamide diacetate, 0.00125% acetyl hexapeptide-8, 0.50% complex humectant, 0.05% red ginseng extract, 0.002% soluble proteoglycan.
Comparative example 1
One embodiment of an anti-aging cosmetic of the present invention, which is identical to that of example 1 except that it does not contain acetyl hexapeptide-8.
Comparative example 2
One example of an anti-aging cosmetic of the present invention was identical to example 1 except that the cosmetic was free of dimethicone/vinyl dimethicone crosspolymer, dipeptide diaminobutyrylbenzylamide diacetate, and acetyl hexapeptide-8.
Comparative example 3
One embodiment of an anti-aging cosmetic of the present invention, which is identical to that of example 1 except that it does not contain a compound moisturizing agent.
Comparative example 4
One embodiment of an anti-aging cosmetic of the present invention is identical to that of example 1 except that it does not contain glyceryl glucoside, dimethicone/vinyl dimethicone crosspolymer, dipeptide diaminobutyrylbenzylamide diacetate, acetyl hexapeptide-8.
Comparative example 5
One embodiment of an anti-aging cosmetic of the present invention is identical to that of example 1 except that it does not contain red ginseng extract.
Comparative example 6
One example of an anti-aging cosmetic of the present invention was identical to example 1 except that it did not contain glyceryl glucoside, dimethicone/vinyl dimethicone crosspolymer, dipeptide diaminobutyrylbenzylamide diacetate, acetyl hexapeptide-8, complex moisturizer, soluble proteoglycan.
Comparative example 7
One embodiment of an anti-aging cosmetic of the present invention, which is identical to that of example 1 except that it does not contain soluble proteoglycan.
Comparative example 8
One example of an anti-aging cosmetic according to the present invention was identical to example 1 except that it did not contain glyceryl glucoside, dimethicone/vinyl dimethicone crosspolymer, dipeptide diaminobutyrylbenzylamide diacetate, acetyl hexapeptide-8, complex moisturizer, and red ginseng extract.
Comparative example 9
One embodiment of an anti-aging cosmetic of the present invention, which is identical to that of example 1 except that it does not contain glycerol glucoside.
Comparative example 10
An example of an anti-aging cosmetic according to the present invention was identical to example 1 except that it did not contain dimethicone/vinyl dimethicone crosspolymer, dipeptide diaminobutyrylbenzylamide diacetate, acetyl hexapeptide-8, complex moisturizer, red ginseng extract, soluble proteoglycan.
EXAMPLE 4 Effect of removing Fine wrinkles in real time
The samples of examples 1-3 and comparative examples 1-10 were tested, and 60 volunteers with obvious eye marks on their eyes aged 25-55 years were selected for each sample, and randomly divided into two groups of 30 persons, one sample for each volunteer and at least 3 hours apart before the next sample. The right eye of one group of volunteers is blank control without using any eye care product, the left eye uses the test sample after cleaning face, the left eye of the other group of volunteers is blank control without using any eye care product, the right eye uses the test sample after cleaning face, and after using eye cream for 5 minutes, the conditions of fine wrinkles of the left eye and the right eye are compared and the test result is counted by using a VISIA photographing method.
TABLE 1 statistics of the striae removal effectiveness of each sample
Figure BDA0002473475550000081
Figure BDA0002473475550000091
Note: the effect is shown: the reduction of wrinkle feature count is more than or equal to 25%; the method has the following advantages: the wrinkle feature count is reduced by 5% -25%; and (4) invalidation: wrinkle feature counts are less than or equal to 5% or increased.
From the above table, only by using the glycerol glucoside, the polydimethylsiloxane/vinyl polydimethylsiloxane cross-linked polymer, the dipeptide diaminobutyrylbenzylamide diacetate, the acetyl hexapeptide-8, the compound humectant, the red ginseng extract and the soluble proteoglycan in a compound way, a good and rapid fine grain removing effect can be obtained, and the effect is greatly reduced due to the lack of part of components, which indicates that the components have a synergistic and increasing effect.
Finally, it should be noted that the above embodiments are only used for illustrating the technical solutions of the present invention and not for limiting the protection scope of the present invention, and although the present invention is described in detail with reference to the preferred embodiments, it should be understood by those skilled in the art that modifications or equivalent substitutions can be made on the technical solutions of the present invention without departing from the spirit and scope of the technical solutions of the present invention.

Claims (10)

1. A composition for reducing fine lines, comprising glyceryl glucoside, dimethicone/vinyl dimethicone crosspolymer, dipeptide diaminobutyrylbenzylamide diacetate, acetyl hexapeptide-8, complex moisturizer, red ginseng extract, and soluble proteoglycan; the compound humectant comprises the following components in percentage by mass: 26.87% betaine, 9.75% sodium PCA, 3.78% pyrrolidone carboxylic acid, 5% calcium lactate, 1.12% serine, 1.06% alanine, 1% glycine, 0.43% glutamic acid, 0.34% lysine HCl, 0.32% threonine, 0.29% arginine, 0.04% proline, 25% trehalose and 25% water.
2. Use of the composition of claim 1 for preparing an anti-aging cosmetic.
3. The use according to claim 2, characterized in that said cosmetic comprises essences, gels, eye creams, face creams, neck creams.
4. An anti-aging cosmetic comprising the composition of claim 1.
5. The cosmetic according to claim 4, which comprises the following components in percentage by mass: 1 to 2.5% of glycerol glucoside, 0.4 to 1.2% of polydimethylsiloxane/vinyl polydimethylsiloxane cross-linked polymer, 0.001 to 0.003% of dipeptide diaminobutyrylbenzylamide diacetate, 0.00125 to 0.003% of acetyl hexapeptide-8, 0.5 to 4% of a complex humectant, 0.05 to 0.5% of red ginseng extract, and 0.002 to 0.01% of soluble proteoglycan.
6. The cosmetic as claimed in claim 5, which comprises the following components in percentage by mass: 1.8% glycerol glucoside, 0.8% dimethicone/vinyl dimethicone crosspolymer, 0.0125% dipeptide diaminobutyrylbenzylamide diacetate, 0.0015% acetyl hexapeptide-8, 2% complex humectant, 0.2% red ginseng extract, and 0.005% soluble proteoglycan.
7. The cosmetic according to claim 5, further comprising the following components in percentage by mass: 0.5-2% of shea butter, 1-4% of triisocaprylic glyceride, 1-3% of polydimethylsiloxane, 0.1-0.5% of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, 0.1-0.5% of sodium acrylate/sodium acryloyldimethyl taurate copolymer, 0.5-2% of PEG-100 stearate, 0.5-2% of glycerol stearate, 5-10% of glycerol, 0.02-0.1% of EDTA disodium and 0.02-0.1% of sodium hydroxide.
8. The cosmetic according to claim 5, further comprising the following components in percentage by mass: 0.01-0.06% of essence and 0.2-15% of preservative.
9. The cosmetic according to claim 5, wherein the cosmetic comprises the following components in percentage by mass: 1.8% glycerol glucoside, 0.8% dimethicone/vinyl dimethicone crosspolymer, 0.0125% dipeptide diaminobutyrylbenzylamide diacetate, 0.0015% acetyl hexapeptide-8, 2% complex humectant, 0.2% red ginseng extract, 0.005% soluble proteoglycan, 1% shea butter, 3% glyceryl triisooctanoate, 2% dimethicone, 0.25% acrylic acid/C10-30 alkanol acrylate crosspolymer, 0.3% sodium acrylate/sodium acryloyldimethyl taurate copolymer, 0.6% PEG-100 stearate, 0.6% glyceryl stearate, 7.5% glycerol, 0.02% disodium EDTA, 0.0425% sodium hydroxide, 0.5% preservative, 0.025% perfume and the balance deionized water.
10. The method for preparing a cosmetic according to claim 9, comprising the steps of:
(1) putting the phase A raw material into a water phase pot, stirring and heating to 75-80 ℃, homogenizing for 5min, and then keeping the temperature and stirring until the raw material is uniformly dispersed;
(2) putting the phase B raw material into an oil phase pot, stirring and heating to 77-82 ℃, and stirring until the phase B raw material is completely melted;
(3) pumping the mixture obtained in the steps (1) and (2) into an emulsifying pot through 100-mesh filter cloth, homogenizing for 10min, and continuing to keep the temperature and stir for 5 min;
(4) cooling the mixture in the step (3) to 60 ℃, dissolving the C-phase raw material with a proper amount of pure water, adding the dissolved C-phase raw material into an emulsifying pot, homogenizing for 5min, and stirring until the material body is uniform;
(5) cooling the mixture in the step (4) to 40 ℃, adding the D-phase, E-phase and F-phase raw materials one by one, and stirring the mixture uniformly;
(6) cooling the mixture obtained in the step (5) to 35 ℃, and discharging after the mixture is qualified through inspection;
wherein the phase A raw material comprises: glycerol, glycerol glucoside, acrylic acid/C10-30 alkanol acrylate crosspolymer, sodium acrylate/sodium acryloyldimethyl taurate copolymer and disodium EDTA;
the phase B raw material comprises: dimethicone/vinyl dimethicone crosspolymer, PEG-100 stearate, shea butter, glyceryl triisooctanoate, dimethicone, and glyceryl stearate;
the C phase raw material comprises potassium hydroxide;
the phase D raw material comprises a compound humectant;
the phase E material comprises a preservative;
the F phase raw material comprises essence.
CN202010359535.3A 2020-04-29 2020-04-29 Composition for quickly removing fine lines and application thereof Pending CN111568797A (en)

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CN111956533A (en) * 2020-09-29 2020-11-20 广东丸美生物技术股份有限公司 Wrinkle-removing cream and preparation method thereof
CN112220714A (en) * 2020-09-11 2021-01-15 广州多美生物科技有限公司 Red ginseng vigor activating oxygen eye cream and preparation method thereof
CN112353705A (en) * 2020-11-25 2021-02-12 广东丸美生物技术股份有限公司 Cosmetic composition, preparation method thereof and cosmetic with wrinkle removing and aging delaying effects

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CN112220714A (en) * 2020-09-11 2021-01-15 广州多美生物科技有限公司 Red ginseng vigor activating oxygen eye cream and preparation method thereof
CN111956533A (en) * 2020-09-29 2020-11-20 广东丸美生物技术股份有限公司 Wrinkle-removing cream and preparation method thereof
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Application publication date: 20200825