CN111629730A - 眼部药物组合物 - Google Patents

眼部药物组合物 Download PDF

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Publication number
CN111629730A
CN111629730A CN201880069116.7A CN201880069116A CN111629730A CN 111629730 A CN111629730 A CN 111629730A CN 201880069116 A CN201880069116 A CN 201880069116A CN 111629730 A CN111629730 A CN 111629730A
Authority
CN
China
Prior art keywords
compound
active agent
formula
pharmaceutically acceptable
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201880069116.7A
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English (en)
Chinese (zh)
Inventor
艾伦·韦克曼
马克·H·莱温
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California San Diego UCSD
Original Assignee
University of California San Diego UCSD
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of California San Diego UCSD filed Critical University of California San Diego UCSD
Publication of CN111629730A publication Critical patent/CN111629730A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CN201880069116.7A 2017-08-24 2018-08-24 眼部药物组合物 Pending CN111629730A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762549872P 2017-08-24 2017-08-24
US62/549,872 2017-08-24
PCT/US2018/048025 WO2019040919A1 (en) 2017-08-24 2018-08-24 OCULAR PHARMACEUTICAL COMPOSITIONS

Publications (1)

Publication Number Publication Date
CN111629730A true CN111629730A (zh) 2020-09-04

Family

ID=65439930

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201880069116.7A Pending CN111629730A (zh) 2017-08-24 2018-08-24 眼部药物组合物

Country Status (8)

Country Link
US (3) US11839616B2 (https=)
EP (1) EP3672598A4 (https=)
JP (1) JP2020531511A (https=)
KR (1) KR20200044873A (https=)
CN (1) CN111629730A (https=)
AU (1) AU2018321926B2 (https=)
CA (1) CA3073718A1 (https=)
WO (1) WO2019040919A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2016379444B2 (en) 2015-12-24 2021-04-29 The Regents Of The University Of California CFTR regulators and methods of use thereof
JP2020531511A (ja) 2017-08-24 2020-11-05 ザ・リージエンツ・オブ・ザ・ユニバーシテイー・オブ・カリフオルニア 眼球用医薬組成物
US11957413B2 (en) * 2019-08-06 2024-04-16 University of Pittsburgh—of the Commonwealth System of Higher Education Solitary wave-based trans-lid tonometer
CN115397392A (zh) * 2019-12-05 2022-11-25 Vanda制药公司 眼用药物组合物
JP7826294B2 (ja) * 2020-09-10 2026-03-09 バンダ・ファーマシューティカルズ・インコーポレイテッド Ｐｄｅｉｖ媒介性の疾患又は状態を処置する方法
WO2025179141A1 (en) * 2024-02-22 2025-08-28 Vanda Pharmaceuticals, Inc. Treatment of dry eye disease

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WO2017112951A1 (en) * 2015-12-24 2017-06-29 The Regents Of The University Of California Cftr regulators and methods of use thereof

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WO2017112951A1 (en) * 2015-12-24 2017-06-29 The Regents Of The University Of California Cftr regulators and methods of use thereof

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Title
SUJIN LEE等: "Nanomolar-Potency Aminophenyl-1,3,5-triazine Activators of the", 《J. MED. CHEM.》 *

Also Published As

Publication number Publication date
JP2020531511A (ja) 2020-11-05
AU2018321926B2 (en) 2023-09-21
EP3672598A4 (en) 2021-04-28
US20210154201A1 (en) 2021-05-27
AU2018321926A1 (en) 2020-03-12
RU2020111560A (ru) 2021-09-24
RU2020111560A3 (https=) 2021-10-29
US11839616B2 (en) 2023-12-12
US20240156828A1 (en) 2024-05-16
WO2019040919A1 (en) 2019-02-28
KR20200044873A (ko) 2020-04-29
EP3672598A1 (en) 2020-07-01
CA3073718A1 (en) 2019-02-28
US20250367207A1 (en) 2025-12-04

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Application publication date: 20200904