CA3073718A1 - Ocular pharmaceutical compositions - Google Patents

Ocular pharmaceutical compositions Download PDF

Info

Publication number
CA3073718A1
CA3073718A1 CA3073718A CA3073718A CA3073718A1 CA 3073718 A1 CA3073718 A1 CA 3073718A1 CA 3073718 A CA3073718 A CA 3073718A CA 3073718 A CA3073718 A CA 3073718A CA 3073718 A1 CA3073718 A1 CA 3073718A1
Authority
CA
Canada
Prior art keywords
compound
active agent
formula
pharmaceutically acceptable
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3073718A
Other languages
English (en)
French (fr)
Inventor
Alan Verkman
Marc H. Levin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California San Diego UCSD
Original Assignee
University of California San Diego UCSD
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of California San Diego UCSD filed Critical University of California San Diego UCSD
Publication of CA3073718A1 publication Critical patent/CA3073718A1/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CA3073718A 2017-08-24 2018-08-24 Ocular pharmaceutical compositions Pending CA3073718A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762549872P 2017-08-24 2017-08-24
US62/549,872 2017-08-24
PCT/US2018/048025 WO2019040919A1 (en) 2017-08-24 2018-08-24 OCULAR PHARMACEUTICAL COMPOSITIONS

Publications (1)

Publication Number Publication Date
CA3073718A1 true CA3073718A1 (en) 2019-02-28

Family

ID=65439930

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3073718A Pending CA3073718A1 (en) 2017-08-24 2018-08-24 Ocular pharmaceutical compositions

Country Status (8)

Country Link
US (3) US11839616B2 (https=)
EP (1) EP3672598A4 (https=)
JP (1) JP2020531511A (https=)
KR (1) KR20200044873A (https=)
CN (1) CN111629730A (https=)
AU (1) AU2018321926B2 (https=)
CA (1) CA3073718A1 (https=)
WO (1) WO2019040919A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX383072B (es) 2015-12-24 2025-03-13 Univ California Reguladores del cftr y métodos para su uso
JP2020531511A (ja) 2017-08-24 2020-11-05 ザ・リージエンツ・オブ・ザ・ユニバーシテイー・オブ・カリフオルニア 眼球用医薬組成物
US11957413B2 (en) * 2019-08-06 2024-04-16 University of Pittsburgh—of the Commonwealth System of Higher Education Solitary wave-based trans-lid tonometer
BR112022010871A2 (pt) * 2019-12-05 2022-08-23 Vanda Pharmaceuticals Inc Composições farmacêuticas oftalmológicas
IL300628A (en) * 2020-09-10 2023-04-01 Vanda Pharmaceuticals Inc Methods for the treatment of cyclic diseases or conditions-PDE IV
WO2025179141A1 (en) * 2024-02-22 2025-08-28 Vanda Pharmaceuticals, Inc. Treatment of dry eye disease

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US5236952A (en) 1986-03-11 1993-08-17 Hoffmann-La Roche Inc. Catechol derivatives
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EP1004307B1 (en) * 1998-01-30 2002-09-04 R-Tech Ueno, Ltd. Ophthalmic composition
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MXPA06008606A (es) 2004-01-30 2007-04-13 Vertex Pharma Moduladores de transportadores con casete de union a atp.
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HUE040366T2 (hu) * 2013-08-08 2019-03-28 Galapagos Nv CFTR modulátor tieno[2,3-c]piránok
WO2015168079A1 (en) 2014-04-29 2015-11-05 Infinity Pharmaceuticals, Inc. Pyrimidine or pyridine derivatives useful as pi3k inhibitors
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JP6894902B2 (ja) 2015-12-24 2021-06-30 ザ・リージエンツ・オブ・ザ・ユニバーシテイー・オブ・カリフオルニア Ｃｆｔｒ制御因子及びこの使用方法
MX383072B (es) 2015-12-24 2025-03-13 Univ California Reguladores del cftr y métodos para su uso
CN109302846B (zh) 2015-12-24 2021-05-11 莱斯彼维特有限公司 吲哚啉酮化合物及其在纤维化疾病治疗中的用途
ES2913051T3 (es) * 2015-12-24 2022-05-31 Univ California Reguladores de CFTR y métodos de uso de los mismos
JP2020531511A (ja) 2017-08-24 2020-11-05 ザ・リージエンツ・オブ・ザ・ユニバーシテイー・オブ・カリフオルニア 眼球用医薬組成物

Also Published As

Publication number Publication date
US20250367207A1 (en) 2025-12-04
US11839616B2 (en) 2023-12-12
EP3672598A4 (en) 2021-04-28
JP2020531511A (ja) 2020-11-05
KR20200044873A (ko) 2020-04-29
RU2020111560A (ru) 2021-09-24
WO2019040919A1 (en) 2019-02-28
AU2018321926A1 (en) 2020-03-12
US20240156828A1 (en) 2024-05-16
US20210154201A1 (en) 2021-05-27
RU2020111560A3 (https=) 2021-10-29
EP3672598A1 (en) 2020-07-01
AU2018321926B2 (en) 2023-09-21
CN111629730A (zh) 2020-09-04

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