CN111225690A - 可流动无细胞组织基质产品以及产生方法 - Google Patents

可流动无细胞组织基质产品以及产生方法 Download PDF

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Publication number
CN111225690A
CN111225690A CN201880067631.1A CN201880067631A CN111225690A CN 111225690 A CN111225690 A CN 111225690A CN 201880067631 A CN201880067631 A CN 201880067631A CN 111225690 A CN111225690 A CN 111225690A
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China
Prior art keywords
tissue
composition
tissue matrix
carrier
injection device
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Pending
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CN201880067631.1A
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English (en)
Chinese (zh)
Inventor
辉·许
郦辉
明·F·波默洛
达林·梅西纳
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LifeCell Corp
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LifeCell Corp
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Publication of CN111225690A publication Critical patent/CN111225690A/zh
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/20Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/48Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with macromolecular fillers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/3129Syringe barrels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00Materials characterised by their function or physical properties
    • A61L2400/06Flowable or injectable implant compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/34Materials or treatment for tissue regeneration for soft tissue reconstruction

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Molecular Biology (AREA)
  • Composite Materials (AREA)
  • Materials Engineering (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
CN201880067631.1A 2017-10-19 2018-10-19 可流动无细胞组织基质产品以及产生方法 Pending CN111225690A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762574678P 2017-10-19 2017-10-19
US62/574,678 2017-10-19
PCT/US2018/056630 WO2019079672A1 (en) 2017-10-19 2018-10-19 ACELLULAR TISSUE MATRIX PRODUCTS FLUIDS AND METHODS OF PRODUCTION

Publications (1)

Publication Number Publication Date
CN111225690A true CN111225690A (zh) 2020-06-02

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN201880067631.1A Pending CN111225690A (zh) 2017-10-19 2018-10-19 可流动无细胞组织基质产品以及产生方法

Country Status (8)

Country Link
US (3) US11826488B2 (enExample)
EP (2) EP3697462B1 (enExample)
JP (2) JP7463273B2 (enExample)
CN (1) CN111225690A (enExample)
AU (2) AU2018351314A1 (enExample)
CA (1) CA3075106A1 (enExample)
ES (1) ES2960617T3 (enExample)
WO (1) WO2019079672A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116212112A (zh) * 2023-03-21 2023-06-06 北京桀亚莱福生物技术有限责任公司 一种注射填充材料及其制备和应用

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11123375B2 (en) 2017-10-18 2021-09-21 Lifecell Corporation Methods of treating tissue voids following removal of implantable infusion ports using adipose tissue products
US10821205B2 (en) 2017-10-18 2020-11-03 Lifecell Corporation Adipose tissue products and methods of production
US11246994B2 (en) 2017-10-19 2022-02-15 Lifecell Corporation Methods for introduction of flowable acellular tissue matrix products into a hand
EP3976127B1 (en) 2019-05-30 2025-09-24 LifeCell Corporation Biologic breast implant
WO2021119468A1 (en) * 2019-12-12 2021-06-17 Lifecell Corporation Methods for introduction of flowable acellular tissue matrix products into a hand
WO2025206904A1 (ko) * 2024-03-27 2025-10-02 주식회사 도프 무세포 진피 기질 마이크로 입자를 포함하는 분산액, 이를 포함하는 필러 및 이의 용도

Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003017826A2 (en) * 2001-08-27 2003-03-06 Regeneration Technologies, Inc. Processed soft tissue for topical or internal application
US20070014869A1 (en) * 2005-07-15 2007-01-18 Cormatrix Cardiovascular, Inc. Compositions for reconstruction, replacement or repair of intracardiac tissue
CN102170856A (zh) * 2008-08-04 2011-08-31 阿勒根工业有限公司 包含麻醉剂的透明质酸基凝胶
CN102227225A (zh) * 2008-09-30 2011-10-26 加利福尼亚大学董事会 用于组织修复的使用细胞外基质的组合物和方法
CN105107018A (zh) * 2015-08-19 2015-12-02 李媚 一种无菌可注射材料的制备方法
CN105288702A (zh) * 2014-08-01 2016-02-03 山东大学 一种无细胞多糖真皮基质材料及其制备方法和应用
KR20160049459A (ko) * 2014-10-24 2016-05-09 주식회사 엘앤씨바이오 입자형 무세포 진피와 히알루론산이 전자빔을 통해 물리적으로 가교된 생체 이식용 조성물의 제조방법
US20160184479A1 (en) * 2014-12-24 2016-06-30 Fettech, Llc Tissue-based compositions and methods of use thereof
WO2017031169A1 (en) * 2015-08-17 2017-02-23 The Johns Hopkins University Mesenchymal cell-binding composite material for tissue restoration
CN106492288A (zh) * 2016-10-31 2017-03-15 广州昕生医学材料有限公司 可注射的脱细胞脂肪基质微粒及其在植入剂中的应用
CN107205911A (zh) * 2015-02-09 2017-09-26 阿勒根工业有限公司 用于改善皮肤外观的组合物和方法

Family Cites Families (158)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1562244A (en) 1976-11-11 1980-03-05 Lock P M Wound dressing materials
US4569348A (en) 1980-02-22 1986-02-11 Velcro Usa Inc. Catheter tube holder strap
US4373519A (en) 1981-06-26 1983-02-15 Minnesota Mining And Manufacturing Company Composite wound dressing
US4582640A (en) 1982-03-08 1986-04-15 Collagen Corporation Injectable cross-linked collagen implant material
MX163953B (es) 1984-03-27 1992-07-03 Univ New Jersey Med Procedimiento para preparar una matriz biodegradable a base de colageno
US4969912A (en) 1988-02-18 1990-11-13 Kelman Charles D Human collagen processing and autoimplant use
US4950483A (en) 1988-06-30 1990-08-21 Collagen Corporation Collagen wound healing matrices and process for their production
US5024841A (en) 1988-06-30 1991-06-18 Collagen Corporation Collagen wound healing matrices and process for their production
US4902508A (en) 1988-07-11 1990-02-20 Purdue Research Foundation Tissue graft composition
US4938763B1 (en) 1988-10-03 1995-07-04 Atrix Lab Inc Biodegradable in-situ forming implants and method of producing the same
EP0444149A4 (en) 1988-11-07 1991-10-09 Synergen Incorporated High molecular weight human angiogenic factors
JP2719671B2 (ja) 1989-07-11 1998-02-25 日本ゼオン株式会社 創傷被覆材
US5290558A (en) 1989-09-21 1994-03-01 Osteotech, Inc. Flowable demineralized bone powder composition and its use in bone repair
US5131850A (en) 1989-11-03 1992-07-21 Cryolife, Inc. Method for cryopreserving musculoskeletal tissues
US5104957A (en) 1990-02-28 1992-04-14 Autogenesis Technologies, Inc. Biologically compatible collagenous reaction product and articles useful as medical implants produced therefrom
AU650045B2 (en) 1990-09-12 1994-06-09 Lifecell Corporation Method and apparatus for cryopreparation dry stabilization and rehydration of biological suspensions
US8067149B2 (en) 1990-09-12 2011-11-29 Lifecell Corporation Acellular dermal matrix and method of use thereof for grafting
US5336616A (en) 1990-09-12 1994-08-09 Lifecell Corporation Method for processing and preserving collagen-based tissues for transplantation
US5231169A (en) 1990-10-17 1993-07-27 Norian Corporation Mineralized collagen
US5263971A (en) 1991-02-13 1993-11-23 Life Medical Sciences, Inc. Apparatus for the closure of wide skin defects by stretching of skin
US5254133A (en) 1991-04-24 1993-10-19 Seid Arnold S Surgical implantation device and related method of use
US5149331A (en) 1991-05-03 1992-09-22 Ariel Ferdman Method and device for wound closure
US5160313A (en) 1991-05-14 1992-11-03 Cryolife, Inc. Process for preparing tissue for transplantation
US5645081A (en) 1991-11-14 1997-07-08 Wake Forest University Method of treating tissue damage and apparatus for same
US7198046B1 (en) 1991-11-14 2007-04-03 Wake Forest University Health Sciences Wound treatment employing reduced pressure
US5636643A (en) 1991-11-14 1997-06-10 Wake Forest University Wound treatment employing reduced pressure
US5641518A (en) 1992-11-13 1997-06-24 Purdue Research Foundation Method of repairing bone tissue
US5275826A (en) 1992-11-13 1994-01-04 Purdue Research Foundation Fluidized intestinal submucosa and its use as an injectable tissue graft
US5437651A (en) 1993-09-01 1995-08-01 Research Medical, Inc. Medical suction apparatus
US5549584A (en) 1994-02-14 1996-08-27 The Kendall Company Apparatus for removing fluid from a wound
WO1995024873A1 (en) 1994-03-14 1995-09-21 Cryolife, Inc. Treated tissue for implantation and preparation methods
US5489304A (en) 1994-04-19 1996-02-06 Brigham & Women's Hospital Method of skin regeneration using a collagen-glycosaminoglycan matrix and cultured epithelial autograft
US5906827A (en) 1994-06-03 1999-05-25 Creative Biomolecules, Inc. Matrix for the manufacture of autogenous replacement body parts
US5599852A (en) 1994-10-18 1997-02-04 Ethicon, Inc. Injectable microdispersions for soft tissue repair and augmentation
US5622867A (en) 1994-10-19 1997-04-22 Lifecell Corporation Prolonged preservation of blood platelets
US6485723B1 (en) 1995-02-10 2002-11-26 Purdue Research Foundation Enhanced submucosal tissue graft constructs
US5834232A (en) 1996-05-01 1998-11-10 Zymogenetics, Inc. Cross-linked gelatin gels and methods of making them
US6666892B2 (en) 1996-08-23 2003-12-23 Cook Biotech Incorporated Multi-formed collagenous biomaterial medical device
US6066325A (en) 1996-08-27 2000-05-23 Fusion Medical Technologies, Inc. Fragmented polymeric compositions and methods for their use
US6998418B1 (en) 1996-11-05 2006-02-14 Gp Medical, Inc. Acellular biological material chemically treated with genipin
WO1998019719A1 (en) 1996-11-05 1998-05-14 Purdue Research Foundation Myocardial graft constructs
AUPO599897A0 (en) 1997-04-03 1997-05-01 Vidal, Linus Clear collagen for facial implants
US5993844A (en) 1997-05-08 1999-11-30 Organogenesis, Inc. Chemical treatment, without detergents or enzymes, of tissue to form an acellular, collagenous matrix
US6135116A (en) 1997-07-28 2000-10-24 Kci Licensing, Inc. Therapeutic method for treating ulcers
US6613278B1 (en) 1998-11-13 2003-09-02 Regeneration Technologies, Inc. Tissue pooling process
GB9719520D0 (en) 1997-09-12 1997-11-19 Kci Medical Ltd Surgical drape and suction heads for wound treatment
US6371992B1 (en) 1997-12-19 2002-04-16 The Regents Of The University Of California Acellular matrix grafts: preparation and use
US6071267A (en) 1998-02-06 2000-06-06 Kinetic Concepts, Inc. Medical patient fluid management interface system and method
US6326018B1 (en) 1998-02-27 2001-12-04 Musculoskeletal Transplant Foundation Flexible sheet of demineralized bone
US20030039678A1 (en) 1998-03-16 2003-02-27 Stone Kevin R. Xenograft bone matrix for orthopedic applications
US6179872B1 (en) 1998-03-17 2001-01-30 Tissue Engineering Biopolymer matt for use in tissue repair and reconstruction
US5951597A (en) 1998-04-14 1999-09-14 Cardiac Pacemakers, Inc. Coronary sinus lead having expandable matrix anchor
US6432710B1 (en) 1998-05-22 2002-08-13 Isolagen Technologies, Inc. Compositions for regenerating tissue that has deteriorated, and methods for using such compositions
EP1082006B1 (en) 1998-05-26 2006-02-01 Lifecell Corporation Cryopreservation of human red blood cells
US6933326B1 (en) * 1998-06-19 2005-08-23 Lifecell Coporation Particulate acellular tissue matrix
DE69941216D1 (de) 1998-06-19 2009-09-17 Lifecell Corp Teilchenförmige zellfreie gewebematrix
WO2000016822A1 (en) 1998-09-21 2000-03-30 The Brigham And Women's Hospital, Inc. Compositions and methods for tissue repair
US6565874B1 (en) 1998-10-28 2003-05-20 Atrix Laboratories Polymeric delivery formulations of leuprolide with improved efficacy
AU2984700A (en) 1999-02-12 2000-08-29 Collagenesis, Inc. Injectable collagen-based delivery system for bone morphogenic proteins
US6856821B2 (en) 2000-05-26 2005-02-15 Kci Licensing, Inc. System for combined transcutaneous blood gas monitoring and vacuum assisted wound closure
US6599318B1 (en) 1999-11-30 2003-07-29 Shlomo Gabbay Implantable support apparatus and method of using same
US6576265B1 (en) 1999-12-22 2003-06-10 Acell, Inc. Tissue regenerative composition, method of making, and method of use thereof
MXPA03002414A (es) 2000-09-18 2004-07-08 Organogenesis Inc Protesis con injerto de hoja plana tratada por bioingenieria y su uso.
IL139708A0 (en) 2000-11-15 2002-02-10 Amiel Gilad Process of decellularizing biological matrices and acellular biological matrices useful in tissue engineering
US7700819B2 (en) 2001-02-16 2010-04-20 Kci Licensing, Inc. Biocompatible wound dressing
US7763769B2 (en) 2001-02-16 2010-07-27 Kci Licensing, Inc. Biocompatible wound dressing
US7070584B2 (en) 2001-02-20 2006-07-04 Kci Licensing, Inc. Biocompatible wound dressing
JP4451658B2 (ja) 2001-10-18 2010-04-14 ライフセル コーポレーション 組織および器官のリモデリング
CA2476653C (en) 2002-02-21 2009-01-27 Encelle, Inc. Cross-linked bioactive hydrogel matrices
AU2003225516A1 (en) 2002-03-26 2003-10-08 Yissum Research Development Company Of The Hebrew University Of Jerusalem Responsive biomedical composites
US20030225347A1 (en) 2002-06-03 2003-12-04 Argenta Louis C. Directed tissue growth employing reduced pressure
US7498040B2 (en) 2005-10-12 2009-03-03 Lifenet Health Compositions for repair of defects in osseous tissues, and methods of making the same
US20040037735A1 (en) 2002-08-23 2004-02-26 Depaula Carl Alexander Allograft tissue purification process for cleaning bone
US6840960B2 (en) 2002-09-27 2005-01-11 Stephen K. Bubb Porous implant system and treatment method
US7402319B2 (en) 2002-09-27 2008-07-22 Board Of Regents, The University Of Texas System Cell-free tissue replacement for tissue engineering
US7824701B2 (en) 2002-10-18 2010-11-02 Ethicon, Inc. Biocompatible scaffold for ligament or tendon repair
WO2004042068A2 (en) 2002-10-31 2004-05-21 Northwestern University Injectable and bioadhesive polymeric hydrogels as well as related methods of enzymatic preparation
US7115100B2 (en) 2002-11-15 2006-10-03 Ethicon, Inc. Tissue biopsy and processing device
US20040162613A1 (en) 2003-02-06 2004-08-19 Thomas Roballey Cosmetic and reconstructive prosthesis containing a biologically compatible rupture indicator
FR2856305B1 (fr) 2003-06-19 2007-08-24 Inst Nat Sante Rech Med Protheses avec revetements biologiquement actifs
AU2004252571C1 (en) 2003-06-27 2012-03-01 Ethicon, Incorporated Postpartum-derived cells for use in treatment of disease of the heart and circulatory system
CA2533259C (en) 2003-07-21 2014-01-28 Lifecell Corporation Acellular tissue matrices made from galactose .alpha.-1,3-galactose-deficient tissue
US7901461B2 (en) 2003-12-05 2011-03-08 Ethicon, Inc. Viable tissue repair implants and methods of use
EP1734814B1 (en) 2004-03-17 2015-01-21 Revivicor, Inc. Tissue products derived from animals lacking any expression of functional alpha 1,3 galactosyltransferase
KR100680134B1 (ko) 2004-06-10 2007-02-08 박우삼 무세포 진피를 주사가능하도록 입자 형태로 가공한 필러
US20060058892A1 (en) 2004-09-16 2006-03-16 Lesh Michael D Valved tissue augmentation implant
US20060073592A1 (en) 2004-10-06 2006-04-06 Wendell Sun Methods of storing tissue matrices
US7905826B2 (en) 2004-11-03 2011-03-15 Cook Incorporated Methods for modifying vascular vessel walls
DE102005002644A1 (de) 2005-01-19 2006-07-20 Schülke & Mayr GmbH Zusammensetzungen für die hygienische Händedesinfektion und die desinfizierende Händewaschung
WO2006116210A2 (en) 2005-04-25 2006-11-02 Bernstein Eric F Dermal fillers for biomedical applications in mammals and methods of using the same
WO2007038629A2 (en) 2005-09-26 2007-04-05 Lifecell Corporation Dry platelet composition
US7498041B2 (en) 2005-10-12 2009-03-03 Lifenet Health Composition for repair of defects in osseous tissues
JP5002805B2 (ja) 2005-10-14 2012-08-15 財団法人ヒューマンサイエンス振興財団 生物由来スキャフォールドの作製方法
EP1986731A4 (en) 2006-02-09 2012-11-07 Aderans Res Inst Inc APPARATUS AND METHODS FOR DELIVERING FLUID AND MATERIAL TO A SUBJECT
US9050402B2 (en) 2006-03-14 2015-06-09 Kci Licensing, Inc. Method for percutaneously administering reduced pressure treatment using balloon dissection
US9456860B2 (en) 2006-03-14 2016-10-04 Kci Licensing, Inc. Bioresorbable foaming tissue dressing
US20070248575A1 (en) 2006-04-19 2007-10-25 Jerome Connor Bone graft composition
US8753672B2 (en) 2006-04-24 2014-06-17 Coloplast A/S Gelatin non-woven structures produced by a non-toxic dry solvent spinning process
CN101553189A (zh) 2006-05-09 2009-10-07 生命细胞公司 加强的生物组织
JP5050197B2 (ja) 2006-07-31 2012-10-17 財団法人ヒューマンサイエンス振興財団 生物由来スキャフォールドの作製方法
US8110216B2 (en) 2006-11-09 2012-02-07 Kci Licensing, Inc. Methods of making porous bioresorbable dressing comprising casing comprising microspheres
CA2682034C (en) 2007-03-26 2015-01-27 Baxter International Inc. Injectable void filler for soft tissue augmentation
CA2685048A1 (en) 2007-04-26 2008-11-06 Advanced Technologies And Regenerative Medicine, Llc Tissue engineering devices and methods for luminal organs
US9034367B2 (en) 2007-05-10 2015-05-19 Cormatrix Cardiovascular, Inc. Articles for tissue regeneration with biodegradable polymer
BRPI0811668A2 (pt) 2007-06-29 2015-02-10 Kci Licensing Inc "método de ativação da atividade osteogênica ou condrogênica em um sítio em um indivíduo com necessidade do mesmo, método de tratamento de uma deficiência de osso ou de cartilagem em um indivíduo, uso de um aparelho de pressão reduzida, composição para tratamento de uma deficiência de osso ou de cartilagem e uso de um aparelho de pressão reduzida e de uma estrutura de suporte biocompatível"
EP2162142B1 (en) 2007-07-10 2015-12-02 Lifecell Corporation Acellular tissue matrix compositions for tissue repair
US20090024224A1 (en) 2007-07-16 2009-01-22 Chen Silvia S Implantation of cartilage
US9161970B2 (en) 2007-12-12 2015-10-20 Allergan, Inc. Dermal filler
US9782300B2 (en) 2008-02-01 2017-10-10 Kci Licensing, Inc. Fiber-microsphere bioresorbable composite scaffold for wound healing
AU2009218436A1 (en) 2008-02-29 2009-09-03 Coloplast A/S Compositions and methods for augmentation and regeneration of living tissue in a subject
EP2274025B1 (en) 2008-05-13 2017-03-15 KCI Licensing, Inc. Catheter/filament style device for treatment of wounds beneath the surface of the skin
JP5675595B2 (ja) 2008-06-06 2015-02-25 ライフセル コーポレーションLifeCell Corporation 組織マトリックスのエラスターゼ処理
JP5165793B2 (ja) 2008-06-25 2013-03-21 ケーシーアイ ライセンシング インコーポレイテッド 吸収性の減圧マニホルドおよびシステム
WO2009158480A2 (en) 2008-06-26 2009-12-30 Kci Licensing, Inc. Stimulation of cartilage formation using reduced pressure treatment
CA2731082C (en) 2008-08-14 2016-08-09 Kci Licensing, Inc. Tissue scaffold comprising an acellular tissue matrix and sodium acetate
US7927414B2 (en) 2008-09-05 2011-04-19 Ethicon, Inc. Method of manufacturing acellular matrix glue
JP5784500B2 (ja) 2008-11-21 2015-09-24 ライフセル コーポレーションLifeCell Corporation 強化型生物由来物質
RU2011122544A (ru) 2008-12-31 2013-02-10 КейСиАй Лайсензинг Инк. Системы для обеспечения потока текучей среды к нервным тканям
MX2011007080A (es) 2008-12-31 2011-10-17 Kci Licensing Inc Sistema para inducir el flujo de fluido para estimular el crecimiento de tejido.
CA2745867A1 (en) 2008-12-31 2010-07-08 Kci Licensing, Inc. Systems for providing fluid flow to tissues
US20110020271A1 (en) 2009-05-20 2011-01-27 Humacyte, Inc. Elastin for soft tissue augmentation
JP2013501586A (ja) 2009-08-11 2013-01-17 ザ ジョンズ ホプキンス ユニヴァーシティ 処理した脂肪性組織および処理した脂肪性組織の生産物の移入のための組成物および方法
US20110171310A1 (en) 2010-01-13 2011-07-14 Allergan Industrie, Sas Hydrogel compositions comprising vasoconstricting and anti-hemorrhagic agents for dermatological use
JP5818372B2 (ja) 2010-01-22 2015-11-18 ケーシーアイ ライセンシング インク 陰圧創傷療法に関する発泡流体灌注デバイス、システムおよび方法
US8632512B2 (en) 2010-04-09 2014-01-21 Kci Licensing, Inc. Apparatuses, methods, and compositions for the treatment and prophylaxis of chronic wounds
CN103068413B (zh) 2010-07-08 2015-12-16 生命细胞公司 用于使组织基质成形的方法
EP3597226A1 (en) 2010-08-10 2020-01-22 Lifecell Corporation Regenerative tissue scaffolds
BR112013011282B1 (pt) * 2010-11-08 2019-05-14 Allergan Industrie Sas Composição de material de enchimento de tecido mole e método de preparação da mesma
CN102068714A (zh) 2011-01-19 2011-05-25 北京大学 一种胶原海绵及其制备方法
US9375513B2 (en) 2011-04-14 2016-06-28 Lifecell Corporation Regenerative materials
CN103534346A (zh) 2011-04-21 2014-01-22 细胞移植组织工程有限公司 细胞合成颗粒
ES2874487T3 (es) 2011-05-31 2021-11-05 Lifecell Corp Matrices de tejido adiposo
KR102049124B1 (ko) * 2011-10-11 2019-11-26 알레간 홀딩스 프랑스 에스.아.에스. 교차-결합된 히알루론산의 섬조 및 이들의 이용 방법
WO2013070881A1 (en) 2011-11-10 2013-05-16 Lifecell Corporation Method for elimination of space through tissue approximation
EP3501558B1 (en) 2011-12-20 2020-11-25 LifeCell Corporation Flowable tissue products
US9532863B2 (en) 2011-12-20 2017-01-03 Lifecell Corporation Sheet tissue products
US20130210058A1 (en) 2012-02-15 2013-08-15 Lakeland Ventures Development, Llc System for noninvasive determination of water in tissue
EP2841116A1 (en) 2012-04-24 2015-03-04 Lifecell Corporation Flowable tissue matrices
US9999637B2 (en) * 2012-04-24 2018-06-19 Lifecell Corporation Functionalized tissue matrices
WO2014144215A1 (en) 2013-03-15 2014-09-18 The Board Of Trustees Of The Leland Stanford Junior University Injectable composition for in-situ repair and regeneration of an injured ligament or tendon and methods of use
FR3006689A1 (fr) * 2013-06-11 2014-12-12 Benedicte Vincente Tauzin Procede de reticulation de l'acide hyaluronique; procede de preparation d'un hydrogel injectable; hydrogel obtenu; utilisation de l'hydroget obtenu
WO2014198406A1 (en) 2013-06-11 2014-12-18 Anteis S.A. Method for crosslinking hyaluronic acid; method for preparing an injectable hydrogel; hydrogel obtained; use of the obtained hydrogel
US10722614B2 (en) * 2013-09-25 2020-07-28 The University Of Kansas Decellularized hyaline cartilage powder for tissue scaffolds
JP2017517255A (ja) * 2014-05-21 2017-06-29 ミメディクス グループ インコーポレイテッド 微粉化ホウォートンゼリー
EP3197513B1 (en) 2014-09-25 2023-08-02 Acell, Inc. Porous foams derived from extracellular matrix, porous foam ecm medical devices, and methods of use and making thereof
AU2015359286B2 (en) 2014-12-11 2019-05-02 ETH Zürich Graft scaffold for cartilage repair and process for making same
GB201514788D0 (en) 2015-08-20 2015-10-07 Ecole Polytech Malleable scaffold material and uses thereof
US20170224869A1 (en) 2016-02-08 2017-08-10 Lifecell Corporation Biologic breast implant
CA3047816A1 (en) 2016-12-23 2018-06-28 Lifecell Corporation Injectable polyurethanes and applications thereof
US12133930B2 (en) 2017-05-24 2024-11-05 Theramicro, Llc System and methods for soft-tissue augmentation
CA3078432A1 (en) 2017-10-04 2019-05-09 Bio-Change Ltd. Cross-linked protein foams and methods of using thereof a polyvalent cellular scaffold
US11123375B2 (en) 2017-10-18 2021-09-21 Lifecell Corporation Methods of treating tissue voids following removal of implantable infusion ports using adipose tissue products
US10821205B2 (en) 2017-10-18 2020-11-03 Lifecell Corporation Adipose tissue products and methods of production
US11246994B2 (en) 2017-10-19 2022-02-15 Lifecell Corporation Methods for introduction of flowable acellular tissue matrix products into a hand
US12151050B2 (en) 2018-03-01 2024-11-26 Tepha, Inc. Medical devices containing compositions of poly(butylene succinate) and copolymers thereof
CA3115057A1 (en) 2018-10-03 2020-04-09 Establishment Labs S.A. Scaffolding for implantable medical devices and methods of use thereof
EP3976127B1 (en) 2019-05-30 2025-09-24 LifeCell Corporation Biologic breast implant
WO2020247793A1 (en) 2019-06-07 2020-12-10 Lifecell Corporation Injectable mesh

Patent Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003017826A2 (en) * 2001-08-27 2003-03-06 Regeneration Technologies, Inc. Processed soft tissue for topical or internal application
US20070014869A1 (en) * 2005-07-15 2007-01-18 Cormatrix Cardiovascular, Inc. Compositions for reconstruction, replacement or repair of intracardiac tissue
CN102170856A (zh) * 2008-08-04 2011-08-31 阿勒根工业有限公司 包含麻醉剂的透明质酸基凝胶
CN102227225A (zh) * 2008-09-30 2011-10-26 加利福尼亚大学董事会 用于组织修复的使用细胞外基质的组合物和方法
CN105288702A (zh) * 2014-08-01 2016-02-03 山东大学 一种无细胞多糖真皮基质材料及其制备方法和应用
KR20160049459A (ko) * 2014-10-24 2016-05-09 주식회사 엘앤씨바이오 입자형 무세포 진피와 히알루론산이 전자빔을 통해 물리적으로 가교된 생체 이식용 조성물의 제조방법
US20160184479A1 (en) * 2014-12-24 2016-06-30 Fettech, Llc Tissue-based compositions and methods of use thereof
CN107205911A (zh) * 2015-02-09 2017-09-26 阿勒根工业有限公司 用于改善皮肤外观的组合物和方法
WO2017031169A1 (en) * 2015-08-17 2017-02-23 The Johns Hopkins University Mesenchymal cell-binding composite material for tissue restoration
CN105107018A (zh) * 2015-08-19 2015-12-02 李媚 一种无菌可注射材料的制备方法
CN106492288A (zh) * 2016-10-31 2017-03-15 广州昕生医学材料有限公司 可注射的脱细胞脂肪基质微粒及其在植入剂中的应用

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
赵春杰: "《药学专业知识 2 2014》", 31 January 2014, 北京:人民军医出版社 *
金海波等: "《精修线雕埋线抗衰老综合临床实用指南 面部抗衰老 轮廓修正 体型的雕塑 ppdo埋线》", 31 October 2016, 沈阳:辽宁科学技术出版社 *
韩秀萍等: "《医学美容技术》", 31 August 2016, 上海:东华大学出版社 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116212112A (zh) * 2023-03-21 2023-06-06 北京桀亚莱福生物技术有限责任公司 一种注射填充材料及其制备和应用

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