CN111183234A - 在表达pnpla3 i148m变异的患者的肝病治疗中对hsd17b13的抑制 - Google Patents

在表达pnpla3 i148m变异的患者的肝病治疗中对hsd17b13的抑制 Download PDF

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CN111183234A
CN111183234A CN201880065116.XA CN201880065116A CN111183234A CN 111183234 A CN111183234 A CN 111183234A CN 201880065116 A CN201880065116 A CN 201880065116A CN 111183234 A CN111183234 A CN 111183234A
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seq
protein
hsd17b13
nucleic acid
encoding
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辛玉蓉
J·格罗马达
程希平
F·杜威
T·特斯洛维奇·多斯塔尔
C·舒尔曼
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Regeneron Pharmaceuticals Inc
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CN201880065116.XA 2017-10-11 2018-10-11 在表达pnpla3 i148m变异的患者的肝病治疗中对hsd17b13的抑制 Pending CN111183234A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762570985P 2017-10-11 2017-10-11
US62/570,985 2017-10-11
PCT/US2018/055377 WO2019075181A1 (en) 2017-10-11 2018-10-11 INHIBITION OF HSD17B13 IN THE TREATMENT OF HEPATIC DISEASE IN PATIENTS EXPRESSING PNPLA3 I148M VARIATION

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CN111183234A true CN111183234A (zh) 2020-05-19

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CN201880065116.XA Pending CN111183234A (zh) 2017-10-11 2018-10-11 在表达pnpla3 i148m变异的患者的肝病治疗中对hsd17b13的抑制

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US (4) US10961583B2 (https=)
EP (3) EP4685243A3 (https=)
JP (3) JP7434151B2 (https=)
KR (2) KR102694809B1 (https=)
CN (1) CN111183234A (https=)
AU (2) AU2018348195B2 (https=)
CA (1) CA3078883A1 (https=)
IL (2) IL319615A (https=)
MX (1) MX2020003561A (https=)
NZ (1) NZ763161A (https=)
RU (1) RU2020115526A (https=)
SG (1) SG11202003254SA (https=)
WO (1) WO2019075181A1 (https=)

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CN112626199A (zh) * 2021-01-04 2021-04-09 杭州艾迪康医学检验中心有限公司 检测慢性肝炎转化为肝硬化的风险预测位点的引物和方法
CN118813778A (zh) * 2024-07-01 2024-10-22 北京泛生子基因科技有限公司 一种试剂盒、使用方法及存储介质

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JP7507093B2 (ja) 2018-03-21 2024-06-27 リジェネロン・ファーマシューティカルズ・インコーポレイテッド 17β-水酸化ステロイド脱水素酵素13型(HSD17B13)iRNA組成物およびその使用方法
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