TWI849576B - 基因標記的用途 - Google Patents

基因標記的用途 Download PDF

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TWI849576B
TWI849576B TW111143011A TW111143011A TWI849576B TW I849576 B TWI849576 B TW I849576B TW 111143011 A TW111143011 A TW 111143011A TW 111143011 A TW111143011 A TW 111143011A TW I849576 B TWI849576 B TW I849576B
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猪原匡史
岡崎周平
小泉昭夫
川上大輔
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國立研究開發法人國立循環器病研究中心
國立大學法人京都大學
日商島津製作所股份有限公司
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Abstract

本發明提供一種預測腦梗塞的發病風險或發病時期的方法。一種預測腦梗塞未發病的受檢查者的腦梗塞發病時期的方法，包括：檢測步驟，對源自腦梗塞未發病的受檢查者的樣品中有無RNF213 p.R4810K基因多態性進行檢測；以及判定步驟，根據所述檢測步驟中的RNF213 p.R4810K基因多態性的有無，來判定該受檢查者的腦梗塞發病時期是否比通常早。一種用於預測腦梗塞發病風險的基因標記，包含RNF213 p.R4810K基因多態性。一種用於預測腦梗塞發病風險的生物標記，包含RNF213 p.R4810K基因所編碼的多肽。

Description

基因標記的用途
本發明是有關於一種腦梗塞的發病風險或發病時期的預測、及屬於該些研究領域的、尤其是針對正常人而言的腦梗塞發病風險預測方法。
非專利文獻1中揭示有：作為煙霧病(moyamoya disease)的易感基因(susceptibility gene)的RNF213基因多態性(c.14576 G>A,p.R4859K,rs112735431)不僅與煙霧病非偶然地相關聯，而且亦與單側煙霧病或動脈粥樣硬化(atherosclerosis)的顱內主幹動脈狹窄(顱內狹窄)非偶然地相關聯，另一方面，揭示有：並未確認到所述RNF213基因多態性與頸部頸動脈狹窄、腦動脈瘤、腦內出血的非偶然的關聯。
再者，與非專利文獻1中的RNF213基因多態性相關的(c.14576 G>A,p.R4859K,rs112735431)這一表述是基於東北大學團體的命名。於本說明書中，基於京都大學團體的命名而將同一RNF213基因多態性表述為p.R4810K多態性(c.14429 G>A,rs112735431)或僅表述為p.R4810K多態性。兩者是基於胺基酸的計算方法的差異者，且為同一多態性
[現有技術文獻]
[非專利文獻]
[非專利文獻1]「RNF213與煙霧症候群(RNF213 and Moyamoya syndrome)」，宮脇哲，2016年區位神經-血管學會議(Niche Neuro-Angiology Conference 2016)，http://nnac.umin.jp/nnac/NNAC#2016#files/%E5%AE%AE%E8%84%87%E5%85%88%E7%94%9F.pdf
本發明的目的在於提供一種預測腦梗塞的發病風險或發病時期的方法。
腦梗塞被分類為粥樣血栓性腦梗塞(atherothrombotic brain infarction(腦動脈血管栓塞))、腔隙性腦梗塞(lacunar infarction)、及腦栓塞(embolism)三種。
根據本發明者的研究，得知RNF213 p.R4810K基因多態性與粥樣血栓性腦梗塞之間非偶然地具有相關性。根據該情況，而提供如下方法：藉由對源自腦梗塞未發病的受檢查者的樣品中有無RNF213基因多態性進行檢測，來預測該受檢查者的腦梗塞的發病風險或發病時期的方法(或輔助性地進行預測的方法)。
本發明包括以下的發明。
(1)一種預測腦梗塞未發病的受檢查者的腦梗塞發病時期的 方法，包括：檢測步驟，對源自腦梗塞未發病的受檢查者的樣品中有無RNF213 p.R4810K基因多態性進行檢測；以及判定步驟，根據所述檢測步驟中的所述RNF213 p.R4810K基因多態性的有無，來判定該受檢查者的腦梗塞發病時期是否比通常早。
(2)如所述(1)中記載的方法，其中於所述檢測步驟中檢測到所述RNF213 p.R4810K基因多態性的情況下，在所述判定步驟中，判斷為該受檢查者與並不具有所述RNF213 p.R4810K基因多態性的人員相比，腦梗塞發病時期早。
(3)如所述(1)或(2)中記載的方法，其中於所述判定步驟中，基於所述RNF213 p.R4810K基因多態性的有無、及該受檢查者的識別資訊，來判定該受檢查者的腦梗塞發病時期是否比通常早。
(4)一種用於預測腦梗塞發病風險的基因標記，包含RNF213 p.R4810K基因多態性。
(5)一種用於預測腦梗塞發病風險的生物標記，包含RNF213 p.R4810K基因所編碼的多肽。
根據本發明的見解，對於腦梗塞未發病的受檢查者，可自早期階段起便對腦梗塞進行預防或採取對策。
圖1是表示患者選擇順序的流程圖。
圖2是基於腦中風亞型的RNF213 p.R4810K多態性攜帶者與非攜帶者之間的缺血性腦中風的優勢比的森林圖(forest plot)。SE表示標準誤差(standard error)；IV表示逆方差法(inverse variance method)；95%CI表示95%可靠區間；FSR表示福岡腦中風記錄(Fukuoka Stroke registry)；NCVC表示日本國立循環器官疾病中心(National Cerebral and Cardiovascular Center(日本國家顱內與心血管中心))。
圖3是基於性別的RNF213 p.R4810K多態性攜帶者與非攜帶者之間的缺血性腦中風的優勢比的森林圖。SE表示標準誤差(standard error)；IV表示逆方差法(inverse variance method)；95%CI表示95%可靠區間；FSR表示福岡腦中風記錄(Fukuoka Stroke registry)；NCVC表示日本國立循環器官疾病中心(National Cerebral and Cardiovascular Center)。
圖4是與缺血性腦中風相關的RNF213基因座(染色體17的座標77358945-79358945)的區域圖。
圖5是RNF213 p.R4810K多態性攜帶者與非攜帶者之間的腦中風發病年齡的比較。SD表示標准偏差(standard deviation)；IV表示逆方差法(inverse variance method)；95%CI表示95%可靠區間；FSR表示福岡腦中風記錄(Fukuoka Stroke registry)；NCVC表示日本國立循環器官疾病中心(National Cerebral and Cardiovascular Center)。
RNF213(環指蛋白(Ring finger protein)213)(基因庫登記編號(GenBank accession number)NM_001256071.1)近年來被鑑定為煙霧病的疾病易感基因，且存在於人類染色體區域17q25.3中。
RNF213 p.R4810K基因多態性為序列編號2所表示的核苷酸(nucleotide)序列中的73097 G>A的單鹼基多態性(SNP；Single Nucleotide Polymorphism(單核苷酸多態性))。RNF213 p.R4810K如所述現有文獻般已知為煙霧病易感多態性。
根據本發明者等人的研究，已判明：RNF213 p.R4810K多態性使大動脈動脈粥樣硬化症所致的缺血性腦中風(即，腦梗塞)的風險增加。於本說明書中，缺血性腦中風與腦梗塞為相同含義。
缺血性腦中風為近年來的早逝的一個原因，且尤其為亞洲的身體障礙及早逝的主要原因，但缺血性腦中風與特有的遺傳決定相關性仍未知。主要於東亞確認到的、作為腦血管疾病的煙霧病與環指蛋白213(RNF213)這一易感基因相關聯，其調節不全有損小鼠(mouse)腦中的腦灌注。因此，本發明者等人設立RNF213於缺血性腦中風中發揮更通常的作用這一假說，並調查作為煙霧病的最通常的風險的RNF213基因的p.R4810K多態性、與缺血性腦中風及其亞型的關聯。
根據缺血性腦中風的三個獨立的日本研究，本發明者等人對東亞祖先的46,958人(17,752例病例及29,206例正常人例(對照(control)))的病例對照資料(case-control data)進行分析。本發明者等人於固定效應模型(fixed effects model)下進行了東亞人的整合分析(meta-analysis)。
結果，根據東亞人的組合整合分析，顯示出：於基因組(genome)整個區域中，p.R4810K多態性與所有缺血性腦中風(OR(優勢比)1.91，95%CI(95%可靠區間)1.55-2.36，p=1.5×10-9)及大動脈動脈粥樣硬化症(OR 3.58，95%CI 2.55-5.03，p=2.0×10-13)非偶然地存在關聯。於藉由性別而層別化的情況下，該關聯於女性中更明顯(男性中OR 1.50，95%CI 1.14-1.98，p=0.004：女性中OR 2.69，95%CI 1.95-3.69，p=1.2×10-9)。關於腦中風發病的平均年齡，與RNF213 p.R4810K多態性非保持者相比，RNF213 p.R4810K多態性保持者中低4.1歲(p=1.1×10-8)。此處，本說明書中的、「腦梗塞發病時期比通常早」這一用語是指比RNF213 p.R4810K多態性非保持者中的平均腦梗塞發病時期早，或者是指比包含RNF213 p.R4810K多態性保持者及RNF213 p.R4810K多態性非保持者在內的平均腦梗塞發病時期早。
根據該些，可得出如下結論：RNF213 p.R4810K多態性為缺血性腦中風、尤其是大動脈動脈粥樣硬化症的缺血性腦中風的遺傳危險因子。
RNF213 p.R4810K基因多態性為序列編號2所表示的核 苷酸序列中的73097 G>A的單鹼基多態性(SNP；Single Nucleotide Polymorphism(單核苷酸多態性))，可為用於預測腦梗塞發病風險、或者用於輔助預測的基因標記。
序列編號2為包含mysterin基因及其周邊區域的基因[FLJ3520、NPTX1、CARD14、及Raptor(KIAA1303)]的人類第17號染色體去氧核糖核酸(deoxyribonucleic acid，DNA)的部分核苷酸序列，相當於美國國家生物技術資訊中心(National Center for Biotechnology Information，NCBI)中所記錄的Contig #NT010783.15的第43560001~43795000號的核苷酸。
序列編號2所表示的核苷酸序列除了為G或A的第73097位的SNP(於本說明書中，簡稱為73097 G>A)以外，亦可存在為T或C的第4766位的SNP(4766 T>C)、為G或A的第120764位的SNP(120764 G>A)、為G或A的第152917位的SNP(152917 G>A)、及為G或A的第232102位的SNP(232102 G>A)。
再者，於本說明書中，SNP的位置是以序列編號2所表示的核苷酸序列中的核苷酸的位置為基準來記載。例如，「第73097位的SNP」是指序列編號2所表示的核苷酸序列中的第73097位的核苷酸中的SNP。於記載為「73097 G>A」等的情況下，在「>」記號前記載主要對偶基因(major allele)的鹼基(該情況下為G)，在「>」記號後記載次要對偶基因(minor allele)的鹼基(該情況下為A)。
另外，於本說明書中，只要並無特別說明，則核苷酸序 列是作為DNA的序列而記載，但於多核苷酸(polynucleotide)為核糖核酸(Ribonucleic Acid，RNA)的情況下，將胸腺嘧啶(thymine)(T)適宜換用為尿嘧啶(uracil)(U)。
於本發明中，多核苷酸除了包含序列編號2所表示的核苷酸序列的連續部分序列或其互補序列以外，亦可包含任意的附加序列。
於本發明中，多核苷酸較佳為經分離或精製。
於本發明的所述方法的檢測步驟中，在源自從受檢查者採取的生物體的試樣中，對73097 G>A的SNP進行檢測。
人類的人種並無特別限定，較佳為東亞人(東亞人種(East Asian)/蒙古人種(Mongoloid))。
此處，人種(race)為智人(Homo sapiens)種類中的可作為特定的子群(subgroup)來區別的群體。人種具有特有且可區別的基因組合，且藉由利用該基因組合而形成的特徵(精神特徵、以及肉體特徵)來鑑定。相同人種的成員共有共通的遺傳祖先，結果，共有類似的基因組合，因此共有可明確區別的遺傳特徵。
例如，關於世界的主要人類群體，基於23種基因資訊來調查遺傳親緣關係，而分類為非洲人(African)(黑種人(Negroid))、高加索人種(Caucascid)(白種人)、大洋洲人(Oceanian)(澳大利亞人種(Australoid))、東亞人種(蒙古人種)及美洲原住民(native American)五種。
所謂東亞人，是指以日本人、朝鮮人、中國人、臺灣人 及蒙古人的任一者為起源的人。東亞人較佳為日本人、朝鮮人、或中國人。
若為本領域技術人員，則可基於個體的身體特徵、祖籍國、先祖起源的相關資訊等而容易地確定該個體的人種。
作為所述方法中所使用的源自生物體的試樣，可使用可採取基因組DNA的任意的組織、細胞、體液等，就獲得的容易性及低侵入性等觀點而言，較佳為使用毛髮、指甲、皮膚、黏膜、血液、血漿、血清、唾液等。
SNP的檢測方法於該技術領域中是眾所周知的。例如，可使用：限制性片段長度多態性(Restriction Fragment Length Polymorphism，RFLP)(限制酶切斷片段長度多態性)法、聚合酶鏈式反應-單鏈構型多態性(Polymerase Chain Reaction-Single Strand Conformation Polymorphism，PCR-SSCP)(單鏈DNA高次結構多態性分析)法、對偶基因特異性寡核苷酸(Allele Specific Oligonucleotide，ASO)雜交法、序列法、放大折射突變系統(Amplification Refracting Mutation System，ARMS)法、變性濃度梯度凝膠電泳(Denaturing Gradient Gel Electrophoresis)法、RNAseA切斷法、染料標記寡核苷酸連接(Dye-labeled Oligonucleotide Ligation，DOL)法、泰曼(TaqMan)PCR法、引物延伸(primer extension)法、侵入物法(invader method)等。
另外，RNF213 p.R4810K基因所編碼的多肽為包含序列編號1所表示的胺基酸序列的多肽(此處，序列編號1所表示的 胺基酸序列中第4810號的精胺酸經取代為離胺酸)，可為用於預測腦梗塞發病風險的生物標記。
即，如上所述，RNF213 p.R4810K的SNP的變異伴有人類mysterin的第4810號的胺基酸取代(精胺酸→離胺酸)，因此，自受試驗者分離mysterin多肽，並對其第4810號的胺基酸進行鑑定，藉此可預測腦梗塞發病風險、或者可實現用以進行預測的輔助。
[實施例]
以下示出實施例，並對本發明進行具體說明，但本發明不受實施例的限制。
腦中風死亡率雖於過去數十年間減少1)，但就世界而言，腦中風仍為早逝的第二主要原因，亦為身體障礙的主要原因2)。在佔世界人口的31%的東南亞及東亞，腦中風為早逝的主要原因，腦中風的發生率及罹患率穩步增加1,2)。流行病學研究暗示有腦中風亞型的實質性地理差異及人種差異3,4)。心因性栓塞症為西歐各國的缺血性腦中風的通常的病因學亞型5)。另一方面，顱內動脈狹窄引起的大動脈動脈粥樣硬化症在大部分亞洲各國中為主要病因6)。認為環境風險主要因素與遺傳背景的不同為亞洲的大動脈動脈粥樣硬化症的高罹患率的主要原因。最近，藉由大規模的多祖先全基因組(genome wide)關聯整合分析，來鑑定與腦中風及腦中風亞型相關聯的32個基因座7)。該研究中，檢查了約800萬單鹼基多態性(SNPs)。然而，該分析中，將小於1%(<0.01) 的次要對偶基因頻率(minor-allele frequency；MAF)的SNPs除外，進而，缺血性腦中風的亞洲特異性遺傳決定因子仍未知。
17q25.3上的環指蛋白213基因(RNF213)被鑑定為煙霧病的易感基因8,9)。於80%以上的煙霧病患者中檢測到RNF213 p.R4810K多態性(c.14429 G>A，rs112735431)，但東亞的健康受試驗者的對偶基因(allele)攜帶頻率為約2%8,9)。RNF213對作為AAA+ATPase與E3連接酶兩者發揮功能的591kDa蛋白12)進行編碼，且與顱內的主幹部閉塞病變的發病及經降低的腦血流中的代償反應相關聯13,14)。最近，兩個個別研究報告有：具有顱內內頸動脈狹窄或近端大腦中動脈狹窄的東亞非煙霧病患者中的RNF213 p.R4810K多態性的高頻率(20%~25%)10,15)。因此，本發明者等人設立該遺傳變異有可能與亞洲的整體性缺血性腦中風相關聯這一假說。此處，對參加了三個獨立的日本研究的急性缺血性腦中風患者進行分析，調查RNF213 p.R4810K多態性與缺血性腦中風及其亞型的關聯性。
(方法)
(研究設計與參加者)
於該兩階段的病例對照研究中，本發明者等人對來自日本的三例病例對照研究中來自東亞參加者的缺血性腦中風資料進行了研究。本發明者等人將並非東亞子孫的患者及對照除外。主研究(primary study)中，使用包含所有的患者的廣泛的臨床資料及放射線資料的日本國立循環器官疾病研究中心(National Cerebral and Cardiovascular Center；NCVC)的基於醫院的單一群體(NCVC生物庫)。再現研究(replication studies)中，p.R4810K基因型是源自日本生物庫(Biobank Japan)(16,256例缺血性腦中風病例及27,294例對照)、及久山(Hisayama)及Fukuoka Stroke Registry(FSR)試驗(1,113例病例及對照901例)的全基因組的基因型分析資料。該研究自所有的試驗參加者取得了書面同意，且由負有責任的倫理委員會及日本國立循環器官疾病研究中心(NCVC)的倫理委員會認可。
(主研究Primary study)
主研究的參加者是由大阪、關西地區的腦中風及心血管疾病專業的600個床位的第三次中心即日本國立循環器官疾病研究中心(NCVC)募集。將自2012年6月起至2017年5月入院且於NCVC在全面同意書中署名的非心因性腦栓塞症(大動脈動脈粥樣硬化症(large-artery atherosclerosis)、小血管閉塞症(small-vessel occlusion)等)的日本患者383例包含於本研究中。基於日本厚生勞動省的煙霧病研究委員會的基準，將被診斷為心因性腦栓塞症cardioembolic stroke(心因性栓塞型中風)、確定/疑似煙霧病的患者除外17)。患者選擇順序的流程圖是於圖1中詳細敘述。
人口統計學資料、粥樣硬化性危險因子、放射線學觀察結果、及病歷是自藉由腦中風患者的前瞻性研究所收集的資料庫(前瞻性收集資料庫(prospectively-collected database))獲得。腦中風亞型是依照與急性腦中風治療相關的Org 10172基準[the Trial of Org 10172 in Acute Stroke Treatment(TOAST)criteria(Org 10172於急性中風治療中的試驗(TOAST)標準)]而分類18)。腦血管病變是藉由磁共振成像法(magnetic resonance imaging；MRI)及MR血管造影(MR angiography)、或電腦斷層掃描(computed tomography，CT)及CT血管造影(CT angiography)進行鑑定。前部循環狹窄(anterior circulation stenosis)是依照殺鼠靈-阿斯匹靈症狀性顱內疾病(Warfarin-Aspirin Symptomatic Intracranial Disease，WASID)的研究基準19)，而定義為顱內內頸動脈(intracranial internal carotid artery)、大腦中動脈(middle cerebral artery)或大腦前動脈(anterior cerebral artery)中有超過50%(>50%)的直徑減少。同樣地，後部循環狹窄(posterior circulation stenosis)是依照顱內、脊柱後、或大腦後動脈中的所述基準來定義。
對照受試驗者是於2007至2015年間在日本關西地區募集。將潛在對照1,027名中、具有腦梗塞或煙霧病的病歷的16名受試驗者除外。最終選擇1,011名對照受試驗者。收集靜脈血液樣品，分析前於-80℃下保存。如上文所記載般8)，使用泰曼SNP試驗(TaqMan SNP Assays)(應用生物系統(Applied Biosystems)，福斯特城(Foster City)，加州(California，CA))及7300/7500實時PCR系統(7300/7500 Real-Time PCR System)(應用生物系統(Applied Biosystems)，福斯特城(Foster City)，加州(California，CA))進行p.R4810K基因型決定。
(再現研究Replication studies)
藉由自以前的報告7)檢索資料，而進行缺血性腦中風(大動脈動脈粥樣硬化症(large-artery atherosclerosis)、小血管閉塞症(small-vessel occlusion)、及心因性腦栓塞症(cardioembolism))與RNF213 p.R4810K多態性之間的關聯性的確認。具體而言，自日本生物庫(Biobank Japan)項目(project)記錄16,256件缺血性腦中風患者。對照是自岩手醫學大庫(Iwate Medical Megabank(IMM))、基於日本保健中心的多目的分群研究(基於日本公共健康中心的前瞻性研究(Japan Public Health Center-based Prospective study(JPHC)))、日本多機構協同分群研究(Japan Multi-institutional Collaborative Cohort Study(JMICC))、東北醫學大庫(Tohoku Medical Megabank(ToMMo))四個基於人群的研究而獲得。進而，1,113例缺血性腦中風與901例的對照例是自研究日本心血管疾病的久山研究、與日本的急性腦中風患者的基於多機構醫院的記錄即FSR試驗而獲得。
SNP基因型分型(genotyping)是使用因美納(Illumina)的人類全表現微珠晶片(HumanOmniExpress BeadChip)與人類外顯子組微珠晶片(HumanExome BeadChip)的組合分析、或因美納(Illumina)的人類全表現外顯子組微珠晶片(Human OmniExpressExome BeadChip)分析並由理化學研究所生命醫學科學研究中心(理化學研究所綜合醫學科學中心(RIKEN Center for Integrative Medical Sciences))實施。為了將東亞以外的受試驗者 除外，應用用以確定試樣無關的血緣同一性分析(Identity-by-Descent analysis)、及包含主成分分析的標準的品質管理順序。單倍型定相(Haplotype phasing)及基因型插補(genotype imputation)是使用具有符合包含成功率及哈溫(Hardy-Weinberg)平衡試驗的品質管理基準的基因型資料的過濾樣品來實施。使用所插補的對偶基因的投予量來實施全基因組關聯分析[genome-wide association study(GWAS)]，並使其適合於具有加法遺傳模型的邏輯式迴歸模型。本發明者等人取入10個主成分、年齡、性別作為共變量。詳細情況記載於上文7)。
於如下情況下，將樣品除外。
1)缺失變異的比例高(缺失>0.05)的情況
2)所報告的性別或民族性、與遺傳決定的性別或民族性之間存在不一致的情況
3)顯示出潛在關聯性的情況
(統計分析Statistical analysis)
連續變數是以平均±SD來表示，並使用學生t檢定(Student's t-test)進行比較。類別變數是以數值與百分比來表現，並適宜使用卡方檢定(chi-square test)與兩側檢定的費雪精準檢定(two-tailed Fisher's exact test)進行比較。本發明者等人因同型接合體的數量不充分而於主研究中將RNF213多態性與缺血性腦中風的風險之間的關聯性假設為顯性模型來進行試驗。另外，本發明者等人為了與使用插補法(imputation methods)的驗證研究(再 現研究(replication studies))進行比較，而對用於整合分析的邏輯加法模型(log-additive model)下的關聯性進行調查。使用多個邏輯迴歸模型(logistic regression model)同時控制潛在混擾因子(confounding factor)，之後針對各腦中風亞型計算優勢比(OR Ratio)及95%可靠區間CI。模型中所考慮到的變數為年齡(連續)、性別、高血壓、血脂異常症、糖尿病及吸煙。所有的分析是使用JMP Pro 12.2軟體(SAS研究公司(SAS Institute Inc.)，凱里(Cary)，北卡羅來納州(North Carolina，NC))來進行。
認為概率值為兩側，且p<0.05並非偶然。整合分析是使用認為p<5×10-8於基因組整體中並非偶然的逆方差固定效應模型(inverse variance fixed effects model)並藉由審查管理(Review Manager)(RevMan)5.3軟體(北歐科克倫中心(The Nordic Cochrane Center)，丹麥(Denmark)，哥本哈根(Copenhagen))進行。
(結果)
(主研究Primary study)
於主研究中，尤其記錄有非心因性腦栓塞症腦中風患者。滿足所述全面性基準的1,775名非心因性腦栓塞症腦中風患者中的383名(21.6%)同意參加NCVC生物庫，並於本主研究中進行了分析。將NCVC生物庫的參加者與非參加者的兩種患者的特徵示於表1中。與NCVC生物庫的非參加者相比較，參加者更年輕，且女性更少。關於血脂異常症及吸煙習慣，較非參加者而言，參 加者更高，但其他危險因子及腦中風亞型的分佈為同等程度。將本主研究參加者的基線(base line)特性示於表2中。腦中風患者與對照對象相比，年齡更高，女性更少，且具有更大量的動脈粥樣硬化症風險因子。
Figure 111143011-A0305-02-0019-4
 NCVC生物庫參加者與非參加者的患者特性。(Patient characteristics of participants and non-participants in NCVC biobank.)
Figure 111143011-A0305-02-0020-5
 主要研究中參加者的RNF213 p.R4810K變異體的基線特性與患病率。ICA表示內頸動脈。(Baseline characteristics and prevalence of RNF213 p.R4810K variant of participants in the primary study.ICA indicates internal carotid artery.)
發現RNF213 p.R4810K多態性於非心因性腦栓塞症腦中風患者中為5.2%及於正常對照者中為2.1%(粗OR 2.60，95%CI 1.39-4.85，p=0.0019)。對年齡、性別、及動脈粥樣硬化症的危險因子進行調整後，RNF213 p.R4810K多態性與非心因性腦栓塞症 腦中風的關聯仍保持非偶然的狀態(經調整的OR 3.90，95%CI 1.62-9.24，p=0.0026)。與對照受試驗者相比較，僅大動脈動脈粥樣硬化症與多態性非偶然地相關聯(粗OR 5.19，95%CI 2.53-10.64，p=2.6×10-6；經調整的OR 11.45，95%CI 3.46-36.17，p=0.0001)(表3)。
Figure 111143011-A0305-02-0022-6
 主研究中，各中風亞型中的RNF213 p.R4810K變異體的攜帶頻率。非心因性栓塞型中風包括：大動脈動脈粥樣硬化症、小血管閉塞症、以及其他。OR表示相對於對照受試驗者而言的各中風亞型中的RNF213 p.R4810K變異體的存在優勢比；CI表示可靠區間。*按照年齡、性別、高血壓、糖尿病、血脂異常、與吸煙發生率調整。(Carrier frequency of the RNF213 p.R4810K variant in each stroke subtype in the primary study.Noncardioembolic stroke includes large-artery atherosclerosis,small-vessel occlusion,and others.OR indicates odds ratio for the presence of the RNF213 p.R4810K variant in each stroke subtype compared with control subjects；CI,confidence interval.*Adjusted for age,sex,hypertension,diabetes mellitus,dyslipidemia,and smoking incidence.)
基於RNF213 p.R4810K多態性的有無的腦中風患者間的比較中，關於腦中風發病的平均年齡，較非攜帶者而言於RNF213多態性中低(58.1±15.5歲：69.1±13.2歲，p=0.0003)(表4)。
Figure 111143011-A0305-02-0023-8
 主研究中，有RNF213 p.R4810K變異體與無RNF213 p.R4810K變異體的中風患者的比較。(Comparisons between stroke patients with and without RNF213 p.R4810K variant in the primary study.)ICA表示內頸動脈；CI表示可靠區間。(ICA indicates internal carotid artery；CI,confidence interval.)
如自表2及表4得知般，對有無RNF213多態性的受試驗者中的腦梗塞的發病年齡的平均(68.5歲)、與有RNF213多態性的受試驗者的腦梗塞發病年齡(表4中，平均為58.1歲)進行 比較，有RNF213多態性的患者的腦梗塞的發病年齡年輕約11歲。
腦中風患者中，較非攜帶者而言，RNF213多態性攜帶者包含更多的女性(55.0%：27.3%，p=0.011)，且顯示出顱內前部循環狹窄(60.0%：27.3%，p=0.004)及大動脈動脈粥樣硬化症(65.0%：32.5%，p=0.012)的更高的頻率(frequency)。顱外內頸動脈(extracranial internal carotid artery)或後部循環狹窄(posterior circulation stenosis)的產生、及高血壓、糖尿病、血脂異常症及吸煙發生率等現有的動脈粥樣硬化性危險因子於多態性攜帶者與非攜帶者之間並無不同。
(再現研究Replication studies)
關於RNF213 p.R4810K多態性，本發明者等人使用自日本生物庫項目7)記錄的16,256例的缺血性腦中風病例(包含心因性腦栓塞症腦中風)及27,294例的東亞系子孫來進行檢索。確認到RNF213 p.R4810K多態性於所有的缺血性腦中風患者中為2.3%及於通常群體中為1.3%。於RNF213 p.R4810K多態性與和基因型頻率相關的所有的缺血性腦中風(ncase(病例數)=16,256)之間發現非偶然的關聯(OR 1.77，95%CI 1.40-2.24，p=1.6×10-6)。關於腦中風發病的平均年齡，較非攜帶者而言於RNF213 p.R4810K多態性中低(62.1±10.0歲：66.0±10.0歲，p=8.7×10-7)。
僅對大動脈動脈粥樣硬化症(ncase=1,256)的患者進行分析，結果，4.0%的患者具有RNF213 p.R4810K多態性，與RNF213p.R4810K多態性的關聯更顯著(OR 3.10，95%CI 1.98-4.84， p=6.9×10-7；腦中風發病年齡56.9±10.2歲：65.0±9.7歲，p=6.3×10-5)。另外，並未確認到RNF213 p.R4810K多態性、與小血管閉塞症(small-vessel occlusion)(ncase=4,613，OR 1.18，95%CI 0.80-1.72，p=0.403)或心因性腦栓塞症(ncase=710，OR 1.34，95%CI 0.62-2.90，p=0.455；圖2)的非偶然的關聯。於藉由性別而層別化的情況下，該些關聯性於女性中更明顯(男性OR 1.40，95%CI 1.03-1.91，p=0.030，女性OR 2.42，95%CI 1.69-3.45，p=1.3×10-6；圖3)。
圖2是基於腦中風亞型的RNF213 p.R4810K多態性攜帶者與非攜帶者之間的缺血性腦中風的優勢比的森林圖。圖3是基於性別的RNF213 p.R4810K多態性攜帶者與非攜帶者之間的缺血性腦中風的優勢比的森林圖。SE表示標準誤差(standard error)；IV表示逆方差法(inverse variance method)；95%CI表示95%可靠區間；FSR表示福岡腦中風記錄(Fukuoka Stroke registry)；NCVC表示日本國立循環器官疾病中心(National Cerebral and Cardiovascular Center)。
與缺血性腦中風相關的RNF213基因座(染色體17的座標77358945-79358945)的區域圖中，作為該區域的讀序多態性(p=2.6×10-7)是鑑定為rs112735431(RNF213 p.R4810K多態性)(圖4)。
於久山-FSR研究參加者中亦發現同樣的關聯。與對照進行比較，RNF213多態性的攜帶頻率尤其於具有大動脈動脈粥樣硬 化症的患者(OR 4.20，95%CI 1.90-9.28，p=3.8×10-4；圖2)中、及女性(OR 3.73，95%CI 1.10-12.73，p=0.035；圖3)中、所有的缺血性腦中風病例(OR 2.90，95%CI 1.39-6.04，p=0.0045)中非偶然地高。關於腦中風發病的平均年齡，較非攜帶者而言於RNF213多態性中存在更低的傾向(66.6±12.4歲：69.8±10.7歲，p=0.058)。
(組合整合分析Combined meta-analysis)
日本的三個研究中的東亞人的綜合整合分析中，於該RNF213 p.R4810K多態性與缺血性腦中風(OR 1.91，95%CI 1.55-2.36，p=1.5×10-9)及大動脈動脈粥樣硬化症(OR 3.88，95%CI 2.55-5.03，p=2.0×10-13；圖2)之間的基因組整體中顯示出非偶然的關聯。於藉由性別而層別化的情況下，在基因組整體中發現非偶然的關聯(男性中OR 1.50，95%CI 1.14-1.98，p=0.004：女性中OR 2.69，95%CI 1.95-3.69，p=1.2×10-9；圖3)。關於腦中風發病的平均年齡，較非攜帶者而言於RNF213多態性中低4.1歲(95%CI 2.7-5.5歲)(p=1.1×10-8；圖5)。
圖5是RNF213 p.R4810K多態性攜帶者與非攜帶者之間的腦中風發病年齡的比較。
關於該研究的主要觀察結果，RNF213 p.R4810K多態性的攜帶頻率於東亞子孫的缺血性腦中風患者、尤其是具有大動脈動脈粥樣硬化症的患者中，較正常對照受試驗體而言非偶然地高。於藉由性別而層別化的情況下，該關聯於女性中更明顯。兩 個獨立的樣品中的驗證研究完全支持該些見解。
驗證研究保證基因型與表現型的關聯(genotype-phenotype association)顯示出可信賴的關聯性。該些資料顯示出煙霧病與大動脈動脈粥樣硬化症、即RNF213相關血管症之間的相當大的連續性。
本發明者等人的結果示出缺血性腦中風患者的RNF213 p.R4810K多態性的患病率(prevalence)中的明顯的性別特異差異。已經熟知煙霧病於女性患者中更頻繁地發生，煙霧病的女性相對於男性的比率為約1.824)。另外，具有顱內動脈狹窄的女性的缺血性腦中風發病的風險高26)。因此，女性的性別及遺傳多態性會相加或相乘地有助於伴有大動脈動脈粥樣硬化症的缺血性腦中風發病。
本發明對於具有RNF213 p.R4810K多態性的受試驗者而言有效，作為受試驗者，並不限定於實施例中所記載的東亞人。
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27)劉W、塞內維拉特納STMLD、人見T、小林H、羅德爾C、赫爾澤R、克雷默M、沃爾默倫MHJ、察霍娃P、克里切克B、小泉A，「全基因組關聯研究確認高加索煙霧病中無主要始祖變異體」，「遺傳學期刊」，2013; 92: 605-609 (Liu W, Senevirathna STMLD, Hitomi T, Kobayashi H, Roder C, Herzig R, Kraemer M, Voormolen MHJ, Cahova P, Krischek B, Koizumi A. Genome wide association study identifies no major founder variant in Caucasian moyamoya disease. J Genet. 2013; 92: 605-609.) 
<![CDATA[<110>  國立研究開發法人國立循環器病研究中心(National Cerebral and Cardiovascular Center )]]>
                 國立大學法人京都大學(KYOTO UNIVERSITY)
                 日商島津製作所股份有限公司(SHIMADZU CORPORATION)
          <![CDATA[<120>  預測腦梗塞未發病的受檢查者的腦梗塞發病時期的方法、用於預測腦梗塞發病風險的基因標記與生物標記]]>
          <![CDATA[<150>  PCT/JP2018/045915 ]]>
          <![CDATA[<151>  2018-12-13]]>
          <![CDATA[<160>  2        ]]>
          <![CDATA[<210>  1]]>
          <![CDATA[<211>  5207]]>
          <![CDATA[<212>  PRT]]>
          <![CDATA[<213>  Homo sapiens]]>
          <![CDATA[<400>  1]]>
          Met Glu Cys Pro Ser Cys Gln His Val Ser Lys Glu Glu Thr Pro Lys 
          1               5                   10                  15      
          Phe Cys Ser Gln Cys Gly Glu Arg Leu Pro Pro Ala Ala Pro Ile Ala 
                      20                  25                  30          
          Asp Ser Glu Asn Asn Asn Ser Thr Met Ala Ser Ala Ser Glu Gly Glu 
                  35                  40                  45              
          Met Glu Cys Gly Gln Glu Leu Lys Glu Glu Gly Gly Pro Cys Leu Phe 
              50                  55                  60                  
          Pro Gly Ser Asp Ser Trp Gln Glu Asn Pro Glu Glu Pro Cys Ser Lys 
          65                  70                  75                  80  
          Ala Ser Trp Thr Val Gln Glu Ser Lys Lys Lys Lys Arg Lys Lys Lys 
                          85                  90                  95      
          Lys Lys Gly Asn Lys Ser Ala Ser Ser Glu Leu Ala Ser Leu Pro Leu 
                      100                 105                 110         
          Ser Pro Ala Ser Pro Cys His Leu Thr Leu Leu Ser Asn Pro Trp Pro 
                  115                 120                 125             
          Gln Asp Thr Ala Leu Pro His Ser Gln Ala Gln Gln Ser Gly Pro Thr 
              130                 135                 140                 
          Gly Gln Pro Ser Gln Pro Pro Gly Thr Ala Thr Thr Pro Leu Glu Gly 
          145                 150                 155                 160 
          Asp Gly Leu Ser Ala Pro Thr Glu Val Gly Asp Ser Pro Leu Gln Ala 
                          165                 170                 175     
          Gln Ala Leu Gly Glu Ala Gly Val Ala Thr Gly Ser Glu Ala Gln Ser 
                      180                 185                 190         
          Ser Pro Gln Phe Gln Asp His Thr Glu Gly Glu Asp Gln Asp Ala Ser 
                  195                 200                 205             
          Ile Pro Ser Gly Gly Arg Gly Leu Ser Gln Glu Gly Thr Gly Pro Pro 
              210                 215                 220                 
          Thr Ser Ala Gly Glu Gly His Ser Arg Thr Glu Asp Ala Ala Gln Glu 
          225                 230                 235                 240 
          Leu Leu Leu Pro Glu Ser Lys Gly Gly Ser Ser Glu Pro Gly Thr Glu 
                          245                 250                 255     
          Leu Gln Thr Thr Glu Gln Gln Ala Gly Ala Ser Ala Ser Met Ala Val 
                      260                 265                 270         
          Asp Ala Val Ala Glu Pro Ala Asn Ala Val Lys Gly Ala Gly Lys Glu 
                  275                 280                 285             
          Met Lys Glu Lys Thr Gln Arg Met Lys Gln Pro Pro Ala Thr Thr Pro 
              290                 295                 300                 
          Pro Phe Lys Thr His Cys Gln Glu Ala Glu Thr Lys Thr Lys Asp Glu 
          305                 310                 315                 320 
          Met Ala Ala Ala Glu Glu Lys Val Gly Lys Asn Glu Gln Gly Glu Pro 
                          325                 330                 335     
          Glu Asp Leu Lys Lys Pro Glu Gly Lys Asn Arg Ser Ala Ala Ala Val 
                      340                 345                 350         
          Lys Asn Glu Lys Glu Gln Lys Asn Gln Glu Ala Asp Val Gln Glu Val 
                  355                 360                 365             
          Lys Ala Ser Thr Leu Ser Pro Gly Gly Gly Val Thr Val Phe Phe His 
              370                 375                 380                 
          Ala Ile Ile Ser Leu His Phe Pro Phe Asn Pro Asp Leu His Lys Val 
          385                 390                 395                 400 
          Phe Ile Arg Gly Gly Glu Glu Phe Gly Glu Ser Lys Trp Asp Ser Asn 
                          405                 410                 415     
          Ile Cys Glu Leu His Tyr Thr Arg Asp Leu Gly His Asp Arg Val Leu 
                      420                 425                 430         
          Val Glu Gly Ile Val Cys Ile Ser Lys Lys His Leu Asp Lys Tyr Ile 
                  435                 440                 445             
          Pro Tyr Lys Tyr Val Ile Tyr Asn Gly Glu Ser Phe Glu Tyr Glu Phe 
              450                 455                 460                 
          Ile Tyr Lys His Gln Gln Lys Lys Gly Glu Tyr Val Asn Arg Cys Leu 
          465                 470                 475                 480 
          Phe Ile Lys Ser Ser Leu Leu Gly Ser Gly Asp Trp His Gln Tyr Tyr 
                          485                 490                 495     
          Asp Ile Val Tyr Met Lys Pro His Gly Arg Leu Gln Lys Val Met Asn 
                      500                 505                 510         
          His Ile Thr Asp Gly Pro Arg Lys Asp Leu Val Lys Gly Lys Gln Ile 
                  515                 520                 525             
          Ala Ala Ala Leu Met Leu Asp Ser Thr Phe Ser Ile Leu Gln Thr Trp 
              530                 535                 540                 
          Asp Thr Ile Asn Leu Asn Ser Phe Phe Thr Gln Phe Glu Gln Phe Cys 
          545                 550                 555                 560 
          Phe Val Leu Gln Gln Pro Met Ile Tyr Glu Gly Gln Ala Gln Leu Trp 
                          565                 570                 575     
          Thr Asp Leu Gln Tyr Arg Glu Lys Glu Val Lys Arg Tyr Leu Trp Gln 
                      580                 585                 590         
          His Leu Lys Lys His Val Val Pro Leu Pro Asp Gly Lys Ser Thr Asp 
                  595                 600                 605             
          Phe Leu Pro Val Asp Cys Pro Val Arg Ser Lys Leu Lys Thr Gly Leu 
              610                 615                 620                 
          Ile Val Leu Phe Val Val Glu Lys Ile Glu Leu Leu Leu Glu Gly Ser 
          625                 630                 635                 640 
          Leu Asp Trp Leu Cys His Leu Leu Thr Ser Asp Ala Ser Ser Pro Asp 
                          645                 650                 655     
          Glu Phe His Arg Asp Leu Ser His Ile Leu Gly Ile Pro Gln Ser Trp 
                      660                 665                 670         
          Arg Leu Tyr Leu Val Asn Leu Cys Gln Arg Cys Met Asp Thr Arg Thr 
                  675                 680                 685             
          Tyr Thr Trp Leu Gly Ala Leu Pro Val Leu His Cys Cys Met Glu Leu 
              690                 695                 700                 
          Ala Pro Arg His Lys Asp Ala Trp Arg Gln Pro Glu Asp Thr Trp Ala 
          705                 710                 715                 720 
          Ala Leu Glu Gly Leu Ser Phe Ser Pro Phe Arg Glu Gln Met Leu Asp 
                          725                 730                 735     
          Thr Ser Ser Leu Leu Gln Phe Met Arg Glu Lys Gln His Leu Leu Ser 
                      740                 745                 750         
          Ile Asp Glu Pro Leu Phe Arg Ser Trp Phe Ser Leu Leu Pro Leu Ser 
                  755                 760                 765             
          His Leu Val Met Tyr Met Glu Asn Phe Ile Glu His Leu Gly Arg Phe 
              770                 775                 780                 
          Pro Ala His Ile Leu Asp Cys Leu Ser Gly Ile Tyr Tyr Arg Leu Pro 
          785                 790                 795                 800 
          Gly Leu Glu Gln Val Leu Asn Thr Gln Asp Val Gln Asp Val Gln Asn 
                          805                 810                 815     
          Val Gln Asn Ile Leu Glu Met Leu Leu Arg Leu Leu Asp Thr Tyr Arg 
                      820                 825                 830         
          Asp Lys Ile Pro Glu Glu Ala Leu Ser Pro Ser Tyr Leu Thr Val Cys 
                  835                 840                 845             
          Leu Lys Leu His Glu Ala Ile Cys Ser Ser Thr Lys Leu Leu Lys Phe 
              850                 855                 860                 
          Tyr Glu Leu Pro Ala Leu Ser Ala Glu Ile Val Cys Arg Met Ile Arg 
          865                 870                 875                 880 
          Leu Leu Ser Leu Val Asp Ser Ala Gly Gln Arg Asp Glu Thr Gly Asn 
                          885                 890                 895     
          Asn Ser Val Gln Thr Val Phe Gln Gly Thr Leu Ala Ala Thr Lys Arg 
                      900                 905                 910         
          Trp Leu Arg Glu Val Phe Thr Lys Asn Met Leu Thr Ser Ser Gly Ala 
                  915                 920                 925             
          Ser Phe Thr Tyr Val Lys Glu Ile Glu Val Trp Arg Arg Leu Val Glu 
              930                 935                 940                 
          Ile Gln Phe Pro Ala Glu His Gly Trp Lys Glu Ser Leu Leu Gly Asp 
          945                 950                 955                 960 
          Met Glu Trp Arg Leu Thr Lys Glu Glu Pro Leu Ser Gln Ile Thr Ala 
                          965                 970                 975     
          Tyr Cys Asn Ser Cys Trp Asp Thr Lys Gly Leu Glu Asp Ser Val Ala 
                      980                 985                 990         
          Lys Thr Phe Glu Lys Cys Ile Ile  Glu Ala Val Ser Ser  Ala Cys Gln 
                  995                 1000                 1005             
          Ser Gln  Thr Ser Ile Leu Gln  Gly Phe Ser Tyr Ser  Asp Leu Arg 
              1010                 1015                 1020             
          Lys Phe  Gly Ile Val Leu Ser  Ala Val Ile Thr Lys  Ser Trp Pro 
              1025                 1030                 1035             
          Arg Thr  Ala Asp Asn Phe Asp  Asp Ile Leu Lys His  Leu Leu Thr 
              1040                 1045                 1050             
          Leu Ala  Asp Val Lys His Val  Phe Arg Leu Cys Gly  Thr Asp Glu 
              1055                 1060                 1065             
          Lys Ile  Leu Ala Asn Val Thr  Glu Asp Ala Lys Arg  Leu Ile Ala 
              1070                 1075                 1080             
          Val Ala  Asp Ser Val Leu Thr  Lys Val Val Gly Asp  Leu Leu Ser 
              1085                 1090                 1095             
          Gly Thr  Ile Leu Val Gly Gln  Leu Glu Leu Ile Ile  Lys His Lys 
              1100                 1105                 1110             
          Asn Gln  Phe Leu Asp Ile Trp  Gln Leu Arg Glu Lys  Ser Leu Ser 
              1115                 1120                 1125             
          Pro Gln  Asp Glu Gln Cys Ala  Val Glu Glu Ala Leu  Asp Trp Arg 
              1130                 1135                 1140             
          Arg Glu  Glu Leu Leu Leu Leu  Lys Lys Glu Lys Arg  Cys Val Asp 
              1145                 1150                 1155             
          Ser Leu  Leu Lys Met Cys Gly  Asn Val Lys His Leu  Ile Gln Val 
              1160                 1165                 1170             
          Asp Phe  Gly Val Leu Ala Val  Arg His Ser Gln Asp  Leu Ser Ser 
              1175                 1180                 1185             
          Lys Arg  Leu Asn Asp Thr Val  Thr Val Arg Leu Ser  Thr Ser Ser 
              1190                 1195                 1200             
          Asn Ser  Gln Arg Ala Thr His  Tyr His Leu Ser Ser  Gln Val Gln 
              1205                 1210                 1215             
          Glu Met  Ala Gly Lys Ile Asp  Leu Leu Arg Asp Ser  His Ile Phe 
              1220                 1225                 1230             
          Gln Leu  Phe Trp Arg Glu Ala  Ala Glu Pro Leu Ser  Glu Pro Lys 
              1235                 1240                 1245             
          Glu Asp  Gln Glu Ala Ala Glu  Leu Leu Ser Glu Pro  Glu Glu Glu 
              1250                 1255                 1260             
          Ser Glu  Arg His Ile Leu Glu  Leu Glu Glu Val Tyr  Asp Tyr Leu 
              1265                 1270                 1275             
          Tyr Gln  Pro Ser Tyr Arg Lys  Phe Ile Lys Leu His  Gln Asp Leu 
              1280                 1285                 1290             
          Lys Ser  Gly Glu Val Thr Leu  Ala Glu Ile Asp Val  Ile Phe Lys 
              1295                 1300                 1305             
          Asp Phe  Val Asn Lys Tyr Thr  Asp Leu Asp Ser Glu  Leu Lys Ile 
              1310                 1315                 1320             
          Met Cys  Thr Val Asp His Gln  Asp Gln Arg Asp Trp  Ile Lys Asp 
              1325                 1330                 1335             
          Arg Val  Glu Gln Ile Lys Glu  Tyr His His Leu His  Gln Ala Val 
              1340                 1345                 1350             
          His Ala  Ala Lys Val Ile Leu  Gln Val Lys Glu Ser  Leu Gly Leu 
              1355                 1360                 1365             
          Asn Gly  Asp Phe Ser Val Leu  Asn Thr Leu Leu Asn  Phe Thr Asp 
              1370                 1375                 1380             
          Asn Phe  Asp Asp Phe Arg Arg  Glu Thr Leu Asp Gln  Ile Asn Gln 
              1385                 1390                 1395             
          Glu Leu  Ile Gln Ala Lys Lys  Leu Leu Gln Asp Ile  Ser Glu Ala 
              1400                 1405                 1410             
          Arg Cys  Lys Gly Leu Gln Ala  Leu Ser Leu Arg Lys  Glu Phe Ile 
              1415                 1420                 1425             
          Cys Trp  Val Arg Glu Ala Leu  Gly Gly Ile Asn Glu  Leu Lys Val 
              1430                 1435                 1440             
          Phe Val  Asp Leu Ala Ser Ile  Ser Ala Gly Glu Asn  Asp Ile Asp 
              1445                 1450                 1455             
          Val Asp  Arg Val Ala Cys Phe  His Asp Ala Val Gln  Gly Tyr Ala 
              1460                 1465                 1470             
          Ser Leu  Leu Phe Lys Leu Asp  Pro Ser Val Asp Phe  Ser Ala Phe 
              1475                 1480                 1485             
          Met Lys  His Leu Lys Lys Leu  Trp Lys Ala Leu Asp  Lys Asp Gln 
              1490                 1495                 1500             
          Tyr Leu  Pro Arg Lys Leu Cys  Asp Ser Ala Arg Asn  Leu Glu Trp 
              1505                 1510                 1515             
          Leu Lys  Thr Val Asn Glu Ser  His Gly Ser Val Glu  Arg Ser Ser 
              1520                 1525                 1530             
          Leu Thr  Leu Ala Thr Ala Ile  Asn Gln Arg Gly Ile  Tyr Val Ile 
              1535                 1540                 1545             
          Gln Ala  Pro Lys Gly Gly Gln  Lys Ile Ser Pro Asp  Thr Val Leu 
              1550                 1555                 1560             
          His Leu  Ile Leu Pro Glu Ser  Pro Gly Ser His Glu  Glu Ser Arg 
              1565                 1570                 1575             
          Glu Tyr  Ser Leu Glu Glu Val  Lys Glu Leu Leu Asn  Lys Leu Met 
              1580                 1585                 1590             
          Leu Met  Ser Gly Lys Lys Asp  Arg Asn Asn Thr Glu  Val Glu Arg 
              1595                 1600                 1605             
          Phe Ser  Glu Val Phe Cys Ser  Val Gln Arg Leu Ser  Gln Ala Phe 
              1610                 1615                 1620             
          Ile Asp  Leu His Ser Ala Gly  Asn Met Leu Phe Arg  Thr Trp Ile 
              1625                 1630                 1635             
          Ala Met  Ala Tyr Cys Ser Pro  Lys Gln Gly Val Ser  Leu Gln Met 
              1640                 1645                 1650             
          Asp Phe  Gly Leu Asp Leu Val  Thr Glu Leu Lys Glu  Gly Gly Asp 
              1655                 1660                 1665             
          Val Thr  Glu Leu Leu Ala Ala  Leu Cys Arg Gln Met  Glu His Phe 
              1670                 1675                 1680             
          Leu Asp  Ser Trp Lys Arg Phe  Val Thr Gln Lys Arg  Met Glu His 
              1685                 1690                 1695             
          Phe Tyr  Leu Asn Phe Tyr Thr  Ala Glu Gln Leu Val  Tyr Leu Ser 
              1700                 1705                 1710             
          Thr Glu  Leu Arg Lys Gln Pro  Pro Ser Asp Ala Ala  Leu Thr Met 
              1715                 1720                 1725             
          Leu Ser  Phe Ile Lys Ser Asn  Cys Thr Leu Arg Asp  Val Leu Arg 
              1730                 1735                 1740             
          Ala Ser  Val Gly Cys Gly Ser  Glu Ala Ala Arg Tyr  Arg Met Arg 
              1745                 1750                 1755             
          Arg Val  Met Glu Glu Leu Pro  Leu Met Leu Leu Ser  Glu Phe Ser 
              1760                 1765                 1770             
          Leu Val  Asp Lys Leu Arg Ile  Ile Met Glu Gln Ser  Met Arg Cys 
              1775                 1780                 1785             
          Leu Pro  Ala Phe Leu Pro Asp  Cys Leu Asp Leu Glu  Thr Leu Gly 
              1790                 1795                 1800             
          His Cys  Leu Ala His Leu Ala  Gly Met Gly Gly Ser  Pro Val Glu 
              1805                 1810                 1815             
          Arg Cys  Leu Pro Arg Gly Leu  Gln Val Gly Gln Pro  Asn Leu Val 
              1820                 1825                 1830             
          Val Cys  Gly His Ser Glu Val  Leu Pro Ala Ala Leu  Ala Val Tyr 
              1835                 1840                 1845             
          Met Gln  Thr Pro Ser Gln Pro  Leu Pro Thr Tyr Asp  Glu Val Leu 
              1850                 1855                 1860             
          Leu Cys  Thr Pro Ala Thr Thr  Phe Glu Glu Val Ala  Leu Leu Leu 
              1865                 1870                 1875             
          Arg Arg  Cys Leu Thr Leu Gly  Ser Leu Gly His Lys  Val Tyr Ser 
              1880                 1885                 1890             
          Leu Leu  Phe Ala Asp Gln Leu  Ser Tyr Glu Val Ala  Arg Gln Ala 
              1895                 1900                 1905             
          Glu Glu  Leu Phe His Asn Leu  Cys Thr Gln Gln His  Arg Glu Asp 
              1910                 1915                 1920             
          Tyr Gln  Leu Val Met Val Cys  Asp Gly Asp Trp Glu  His Cys Tyr 
              1925                 1930                 1935             
          Leu Pro  Ser Ala Phe Ser Gln  His Lys Val Phe Val  Thr Pro Gln 
              1940                 1945                 1950             
          Ala Pro  Leu Glu Ala Ile Gln  Ala Tyr Leu Ala Gly  His Tyr Arg 
              1955                 1960                 1965             
          Val Pro  Lys Gln Thr Leu Ser  Ala Ala Ala Val Phe  Asn Asp Arg 
              1970                 1975                 1980             
          Leu Cys  Val Gly Ile Val Ala  Ser Glu Arg Ala Gly  Val Gly Lys 
              1985                 1990                 1995             
          Ser Leu  Tyr Val Lys Arg Leu  His Asp Lys Met Lys  Met Gln Leu 
              2000                 2005                 2010             
          Asn Val  Lys Asn Val Pro Leu  Lys Thr Ile Arg Leu  Ile Asp Pro 
              2015                 2020                 2025             
          Gln Val  Asp Glu Ser Arg Val  Leu Gly Ala Leu Leu  Pro Phe Leu 
              2030                 2035                 2040             
          Asp Ala  Gln Tyr Gln Lys Val  Pro Val Leu Phe His  Leu Asp Val 
              2045                 2050                 2055             
          Thr Ser  Ser Val Gln Thr Gly  Ile Trp Val Phe Leu  Phe Lys Leu 
              2060                 2065                 2070             
          Leu Ile  Leu Gln Tyr Leu Met  Asp Ile Asn Gly Lys  Met Trp Leu 
              2075                 2080                 2085             
          Arg Asn  Pro Cys His Leu Tyr  Ile Val Glu Ile Leu  Glu Arg Arg 
              2090                 2095                 2100             
          Thr Ser  Val Pro Ser Arg Ser  Ser Ser Ala Leu Arg  Thr Arg Val 
              2105                 2110                 2115             
          Pro Gln  Phe Ser Phe Leu Asp  Ile Phe Pro Lys Val  Thr Cys Arg 
              2120                 2125                 2130             
          Pro Pro  Lys Glu Val Ile Asp  Met Glu Leu Ser Ala  Leu Arg Ser 
              2135                 2140                 2145             
          Asp Thr  Glu Pro Gly Met Asp  Leu Trp Glu Phe Cys  Ser Glu Thr 
              2150                 2155                 2160             
          Phe Gln  Arg Pro Tyr Gln Tyr  Leu Arg Arg Phe Asn  Gln Asn Gln 
              2165                 2170                 2175             
          Asp Leu  Asp Thr Phe Gln Tyr  Gln Glu Gly Ser Val  Glu Gly Thr 
              2180                 2185                 2190             
          Pro Glu  Glu Cys Leu Gln His  Phe Leu Phe His Cys  Gly Val Ile 
              2195                 2200                 2205             
          Asn Pro  Ser Trp Ser Glu Leu  Arg Asn Phe Ala Arg  Phe Leu Asn 
              2210                 2215                 2220             
          Tyr Gln  Leu Arg Asp Cys Glu  Ala Ser Leu Phe Cys  Asn Pro Ser 
              2225                 2230                 2235             
          Phe Ile  Gly Asp Thr Leu Arg  Gly Phe Lys Lys Phe  Val Val Thr 
              2240                 2245                 2250             
          Phe Met  Ile Phe Met Ala Arg  Asp Phe Ala Thr Pro  Ser Leu His 
              2255                 2260                 2265             
          Thr Ser  Asp Gln Ser Pro Gly  Lys His Met Val Thr  Met Asp Gly 
              2270                 2275                 2280             
          Val Arg  Glu Glu Asp Leu Ala  Pro Phe Ser Leu Arg  Lys Arg Trp 
              2285                 2290                 2295             
          Glu Ser  Glu Pro His Pro Tyr  Val Phe Phe Asn Asp  Asp His Thr 
              2300                 2305                 2310             
          Thr Met  Thr Phe Ile Gly Phe  His Leu Gln Pro Asn  Ile Asn Gly 
              2315                 2320                 2325             
          Ser Val  Asp Ala Ile Ser His  Leu Thr Gly Lys Val  Ile Lys Arg 
              2330                 2335                 2340             
          Asp Val  Met Thr Arg Asp Leu  Tyr Gln Gly Leu Leu  Leu Gln Arg 
              2345                 2350                 2355             
          Val Pro  Phe Asn Val Asp Phe  Asp Lys Leu Pro Arg  His Lys Lys 
              2360                 2365                 2370             
          Leu Glu  Arg Leu Cys Leu Thr  Leu Gly Ile Pro Gln  Ala Thr Asp 
              2375                 2380                 2385             
          Pro Asp  Lys Thr Tyr Glu Leu  Thr Thr Asp Asn Met  Leu Lys Ile 
              2390                 2395                 2400             
          Leu Ala  Ile Glu Met Arg Phe  Arg Cys Gly Ile Pro  Val Ile Ile 
              2405                 2410                 2415             
          Met Gly  Glu Thr Gly Cys Gly  Lys Thr Arg Leu Ile  Lys Phe Leu 
              2420                 2425                 2430             
          Ser Asp  Leu Arg Arg Gly Gly  Thr Asn Ala Asp Thr  Ile Lys Leu 
              2435                 2440                 2445             
          Val Lys  Val His Gly Gly Thr  Thr Ala Asp Met Ile  Tyr Ser Arg 
              2450                 2455                 2460             
          Val Arg  Glu Ala Glu Asn Val  Ala Phe Ala Asn Lys  Asp Gln His 
              2465                 2470                 2475             
          Gln Leu  Asp Thr Ile Leu Phe  Phe Asp Glu Ala Asn  Thr Thr Glu 
              2480                 2485                 2490             
          Ala Ile  Ser Cys Ile Lys Glu  Val Leu Cys Asp His  Met Val Asp 
              2495                 2500                 2505             
          Gly Gln  Pro Leu Ala Glu Asp  Ser Gly Leu His Ile  Ile Ala Ala 
              2510                 2515                 2520             
          Cys Asn  Pro Tyr Arg Lys His  Ser Glu Glu Met Ile  Cys Arg Leu 
              2525                 2530                 2535             
          Glu Ser  Ala Gly Leu Gly Tyr  Arg Val Ser Met Glu  Glu Thr Ala 
              2540                 2545                 2550             
          Asp Arg  Leu Gly Ser Ile Pro  Leu Arg Gln Leu Val  Tyr Arg Val 
              2555                 2560                 2565             
          His Ala  Leu Pro Pro Ser Leu  Ile Pro Leu Val Trp  Asp Phe Gly 
              2570                 2575                 2580             
          Gln Leu  Ser Asp Val Ala Glu  Lys Leu Tyr Ile Gln  Gln Ile Val 
              2585                 2590                 2595             
          Gln Arg  Leu Val Glu Ser Ile  Ser Leu Asp Glu Asn  Gly Thr Arg 
              2600                 2605                 2610             
          Val Ile  Thr Glu Val Leu Cys  Ala Ser Gln Gly Phe  Met Arg Lys 
              2615                 2620                 2625             
          Thr Glu  Asp Glu Cys Ser Phe  Val Ser Leu Arg Asp  Val Glu Arg 
              2630                 2635                 2640             
          Cys Val  Lys Val Phe Arg Trp  Phe His Glu His Ser  Ala Met Leu 
              2645                 2650                 2655             
          Leu Ala  Gln Leu Asn Ala Phe  Leu Ser Lys Ser Ser  Val Ser Lys 
              2660                 2665                 2670             
          Asn His  Thr Glu Arg Asp Pro  Val Leu Trp Ser Leu  Met Leu Ala 
              2675                 2680                 2685             
          Ile Gly  Val Cys Tyr His Ala  Ser Leu Glu Lys Lys  Asp Ser Tyr 
              2690                 2695                 2700             
          Arg Lys  Ala Ile Ala Arg Phe  Phe Pro Lys Pro Tyr  Asp Asp Ser 
              2705                 2710                 2715             
          Arg Leu  Leu Leu Asp Glu Ile  Thr Arg Ala Gln Asp  Leu Phe Leu 
              2720                 2725                 2730             
          Asp Gly  Val Pro Leu Arg Lys  Thr Ile Ala Lys Asn  Leu Ala Leu 
              2735                 2740                 2745             
          Lys Glu  Asn Val Phe Met Met  Val Val Cys Ile Glu  Leu Lys Ile 
              2750                 2755                 2760             
          Pro Leu  Phe Leu Val Gly Lys  Pro Gly Ser Ser Lys  Ser Leu Ala 
              2765                 2770                 2775             
          Lys Thr  Ile Val Ala Asp Ala  Met Gln Gly Pro Ala  Ala Tyr Ser 
              2780                 2785                 2790             
          Asp Leu  Phe Arg Ser Leu Lys  Gln Val His Leu Val  Ser Phe Gln 
              2795                 2800                 2805             
          Cys Ser  Pro His Ser Thr Pro  Gln Gly Ile Ile Ser  Thr Phe Arg 
              2810                 2815                 2820             
          Gln Cys  Ala Arg Phe Gln Gln  Gly Lys Asp Leu Gln  Gln Tyr Val 
              2825                 2830                 2835             
          Ser Val  Val Val Leu Asp Glu  Val Gly Leu Ala Glu  Asp Ser Pro 
              2840                 2845                 2850             
          Lys Met  Pro Leu Lys Thr Leu  His Pro Leu Leu Glu  Asp Gly Cys 
              2855                 2860                 2865             
          Ile Glu  Asp Asp Pro Ala Pro  His Lys Lys Val Gly  Phe Val Gly 
              2870                 2875                 2880             
          Ile Ser  Asn Trp Ala Leu Asp  Pro Ala Lys Met Asn  Arg Gly Ile 
              2885                 2890                 2895             
          Phe Val  Ser Arg Gly Ser Pro  Asn Glu Thr Glu Leu  Ile Glu Ser 
              2900                 2905                 2910             
          Ala Lys  Gly Ile Cys Ser Ser  Asp Ile Leu Val Gln  Asp Arg Val 
              2915                 2920                 2925             
          Gln Gly  Tyr Phe Ala Ser Phe  Ala Lys Ala Tyr Glu  Thr Val Cys 
              2930                 2935                 2940             
          Lys Arg  Gln Asp Lys Glu Phe  Phe Gly Leu Arg Asp  Tyr Tyr Ser 
              2945                 2950                 2955             
          Leu Ile  Lys Met Val Phe Ala  Ala Ala Lys Ala Ser  Asn Arg Lys 
              2960                 2965                 2970             
          Pro Ser  Pro Gln Asp Ile Ala  Gln Ala Val Leu Arg  Asn Phe Ser 
              2975                 2980                 2985             
          Gly Lys  Asp Asp Ile Gln Ala  Leu Asp Ile Phe Leu  Ala Asn Leu 
              2990                 2995                 3000             
          Pro Glu  Ala Lys Cys Ser Glu  Glu Val Ser Pro Met  Gln Leu Ile 
              3005                 3010                 3015             
          Lys Gln  Asn Ile Phe Gly Pro  Ser Gln Lys Val Pro  Gly Gly Glu 
              3020                 3025                 3030             
          Gln Glu  Asp Ala Glu Ser Arg  Tyr Leu Leu Val Leu  Thr Lys Asn 
              3035                 3040                 3045             
          Tyr Val  Ala Leu Gln Ile Leu  Gln Gln Thr Phe Phe  Glu Gly Asp 
              3050                 3055                 3060             
          Gln Gln  Pro Glu Ile Ile Phe  Gly Ser Gly Phe Pro  Lys Asp Gln 
              3065                 3070                 3075             
          Glu Tyr  Thr Gln Leu Cys Arg  Asn Ile Asn Arg Val  Lys Ile Cys 
              3080                 3085                 3090             
          Met Glu  Thr Gly Lys Met Val  Leu Leu Leu Asn Leu  Gln Asn Leu 
              3095                 3100                 3105             
          Tyr Glu  Ser Leu Tyr Asp Ala  Leu Asn Gln Tyr Tyr  Val His Leu 
              3110                 3115                 3120             
          Gly Gly  Gln Lys Tyr Val Asp  Leu Gly Leu Gly Thr  His Arg Val 
              3125                 3130                 3135             
          Lys Cys  Arg Val His Pro Asn  Phe Arg Leu Ile Val  Ile Glu Glu 
              3140                 3145                 3150             
          Lys Asp  Val Ala Tyr Lys His  Phe Pro Ile Pro Leu  Ile Asn Arg 
              3155                 3160                 3165             
          Leu Glu  Lys His Tyr Leu Asp  Ile Asn Thr Val Leu  Glu Lys Trp 
              3170                 3175                 3180             
          Gln Lys  Ser Ile Val Glu Glu  Leu Cys Ala Trp Val  Glu Lys Phe 
              3185                 3190                 3195             
          Ile Asn  Val Lys Ala His His  Phe Gln Lys Arg His  Lys Tyr Ser 
              3200                 3205                 3210             
          Pro Ser  Asp Val Phe Ile Gly  Tyr His Ser Asp Ala  Cys Ala Ser 
              3215                 3220                 3225             
          Val Val  Leu Gln Val Ile Glu  Arg Gln Gly Pro Arg  Ala Leu Thr 
              3230                 3235                 3240             
          Glu Glu  Leu His Gln Lys Val  Ser Glu Glu Ala Lys  Ser Ile Leu 
              3245                 3250                 3255             
          Leu Asn  Cys Ala Thr Pro Asp  Ala Val Val Arg Leu  Ser Ala Tyr 
              3260                 3265                 3270             
          Ser Leu  Gly Gly Phe Ala Ala  Glu Trp Leu Ser Gln  Glu Tyr Phe 
              3275                 3280                 3285             
          His Arg  Gln Arg His Asn Ser  Phe Ala Asp Phe Leu  Gln Ala His 
              3290                 3295                 3300             
          Leu His  Thr Ala Asp Leu Glu  Arg His Ala Ile Phe  Thr Glu Ile 
              3305                 3310                 3315             
          Thr Thr  Phe Ser Arg Leu Leu  Thr Ser His Asp Cys  Glu Ile Leu 
              3320                 3325                 3330             
          Glu Ser  Glu Val Thr Gly Arg  Ala Pro Lys Pro Thr  Leu Leu Trp 
              3335                 3340                 3345             
          Leu Gln  Gln Phe Asp Thr Glu  Tyr Ser Phe Leu Lys  Glu Val Arg 
              3350                 3355                 3360             
          Asn Cys  Leu Thr Asn Thr Ala  Lys Cys Lys Ile Leu  Ile Phe Gln 
              3365                 3370                 3375             
          Thr Asp  Phe Glu Asp Gly Ile  Arg Ser Ala Gln Leu  Ile Ala Ser 
              3380                 3385                 3390             
          Ala Lys  Tyr Ser Val Ile Asn  Glu Ile Asn Lys Ile  Arg Glu Asn 
              3395                 3400                 3405             
          Glu Asp  Arg Ile Phe Val Tyr  Phe Ile Thr Lys Leu  Ser Arg Val 
              3410                 3415                 3420             
          Gly Arg  Gly Thr Ala Tyr Val  Gly Phe His Gly Gly  Leu Trp Gln 
              3425                 3430                 3435             
          Ser Val  His Ile Asp Asp Leu  Arg Arg Ser Thr Leu  Met Val Ser 
              3440                 3445                 3450             
          Asp Val  Thr Arg Leu Gln His  Val Thr Ile Ser Gln  Leu Phe Ala 
              3455                 3460                 3465             
          Pro Gly  Asp Leu Pro Glu Leu  Gly Leu Glu His Arg  Ala Glu Asp 
              3470                 3475                 3480             
          Gly His  Glu Glu Ala Met Glu  Thr Glu Ala Ser Thr  Ser Gly Glu 
              3485                 3490                 3495             
          Val Ala  Glu Val Ala Glu Glu  Ala Met Glu Thr Glu  Ser Ser Glu 
              3500                 3505                 3510             
          Lys Val  Gly Lys Glu Thr Ser  Glu Leu Gly Gly Ser  Asp Val Ser 
              3515                 3520                 3525             
          Ile Leu  Asp Thr Thr Arg Leu  Leu Arg Ser Cys Val  Gln Ser Ala 
              3530                 3535                 3540             
          Val Gly  Met Leu Arg Asp Gln  Asn Glu Ser Cys Thr  Arg Asn Met 
              3545                 3550                 3555             
          Arg Arg  Val Val Leu Leu Leu  Gly Leu Leu Asn Glu  Asp Asp Ala 
              3560                 3565                 3570             
          Cys His  Ala Ser Phe Leu Arg  Val Ser Lys Met Arg  Leu Ser Val 
              3575                 3580                 3585             
          Phe Leu  Lys Lys Gln Glu Glu  Ser Gln Phe His Pro  Leu Glu Trp 
              3590                 3595                 3600             
          Leu Ala  Arg Glu Ala Cys Asn  Gln Asp Ala Leu Gln  Glu Ala Gly 
              3605                 3610                 3615             
          Thr Phe  Arg His Thr Leu Trp  Lys Arg Val Gln Gly  Ala Val Thr 
              3620                 3625                 3630             
          Pro Leu  Leu Ala Ser Met Ile  Ser Phe Ile Asp Arg  Asp Gly Asn 
              3635                 3640                 3645             
          Leu Glu  Leu Leu Thr Arg Pro  Asp Thr Pro Pro Trp  Ala Arg Asp 
              3650                 3655                 3660             
          Leu Trp  Met Phe Ile Phe Ser  Asp Thr Met Leu Leu  Asn Ile Pro 
              3665                 3670                 3675             
          Leu Val  Met Asn Asn Glu Arg  His Lys Gly Glu Met  Ala Tyr Ile 
              3680                 3685                 3690             
          Val Val  Gln Asn His Met Asn  Leu Ser Glu Asn Ala  Ser Asn Asn 
              3695                 3700                 3705             
          Val Pro  Phe Ser Trp Lys Ile  Lys Asp Tyr Leu Glu  Glu Leu Trp 
              3710                 3715                 3720             
          Val Gln  Ala Gln Tyr Ile Thr  Asp Ala Glu Gly Leu  Pro Lys Lys 
              3725                 3730                 3735             
          Phe Val  Asp Ile Phe Gln Gln  Thr Pro Leu Gly Arg  Phe Leu Ala 
              3740                 3745                 3750             
          Gln Leu  His Gly Glu Pro Gln  Gln Glu Leu Leu Gln  Cys Tyr Leu 
              3755                 3760                 3765             
          Lys Asp  Phe Ile Leu Leu Thr  Met Arg Val Ser Thr  Glu Glu Glu 
              3770                 3775                 3780             
          Leu Lys  Phe Leu Gln Met Ala  Leu Trp Ser Cys Thr  Arg Lys Leu 
              3785                 3790                 3795             
          Lys Ala  Ala Ser Glu Ala Pro  Glu Glu Glu Val Ser  Leu Pro Trp 
              3800                 3805                 3810             
          Val His  Leu Ala Tyr Gln Arg  Phe Arg Ser Arg Leu  Gln Asn Phe 
              3815                 3820                 3825             
          Ser Arg  Ile Leu Thr Ile Tyr  Pro Gln Val Leu His  Ser Leu Met 
              3830                 3835                 3840             
          Glu Ala  Arg Trp Asn His Glu  Leu Ala Gly Cys Glu  Met Thr Leu 
              3845                 3850                 3855             
          Asp Ala  Phe Ala Ala Met Ala  Cys Thr Glu Met Leu  Thr Arg Asn 
              3860                 3865                 3870             
          Thr Leu  Lys Pro Ser Pro Gln  Ala Trp Leu Gln Leu  Val Lys Asn 
              3875                 3880                 3885             
          Leu Ser  Met Pro Leu Glu Leu  Ile Cys Ser Asp Glu  His Met Gln 
              3890                 3895                 3900             
          Gly Ser  Gly Ser Leu Ala Gln  Ala Val Ile Arg Glu  Val Arg Ala 
              3905                 3910                 3915             
          Gln Trp  Ser Arg Ile Phe Ser  Thr Ala Leu Phe Val  Glu His Val 
              3920                 3925                 3930             
          Leu Leu  Gly Thr Glu Ser Arg  Val Pro Glu Leu Gln  Gly Leu Val 
              3935                 3940                 3945             
          Thr Glu  His Val Phe Leu Leu  Asp Lys Cys Leu Arg  Glu Asn Ser 
              3950                 3955                 3960             
          Asp Val  Lys Thr His Gly Pro  Phe Glu Ala Val Met  Arg Thr Leu 
              3965                 3970                 3975             
          Cys Glu  Cys Lys Glu Thr Ala  Ser Lys Thr Leu Ser  Arg Phe Gly 
              3980                 3985                 3990             
          Ile Gln  Pro Cys Ser Ile Cys  Leu Gly Asp Ala Lys  Asp Pro Val 
              3995                 4000                 4005             
          Cys Leu  Pro Cys Asp His Val  His Cys Leu Arg Cys  Leu Arg Ala 
              4010                 4015                 4020             
          Trp Phe  Ala Ser Glu Gln Met  Ile Cys Pro Tyr Cys  Leu Thr Ala 
              4025                 4030                 4035             
          Leu Pro  Asp Glu Phe Ser Pro  Ala Val Ser Gln Ala  His Arg Glu 
              4040                 4045                 4050             
          Ala Ile  Glu Lys His Ala Arg  Phe Arg Gln Met Cys  Asn Ser Phe 
              4055                 4060                 4065             
          Phe Val  Asp Leu Val Ser Thr  Ile Cys Phe Lys Asp  Asn Ala Pro 
              4070                 4075                 4080             
          Pro Glu  Lys Glu Val Ile Glu  Ser Leu Leu Ser Leu  Leu Phe Val 
              4085                 4090                 4095             
          Gln Lys  Gly Arg Leu Arg Asp  Ala Ala Gln Arg His  Cys Glu His 
              4100                 4105                 4110             
          Thr Lys  Ser Leu Ser Pro Phe  Asn Asp Val Val Asp  Lys Thr Pro 
              4115                 4120                 4125             
          Val Ile  Arg Ser Val Ile Leu  Lys Leu Leu Leu Lys  Tyr Ser Phe 
              4130                 4135                 4140             
          His Asp  Val Lys Asp Tyr Ile  Gln Glu Tyr Leu Thr  Leu Leu Lys 
              4145                 4150                 4155             
          Lys Lys  Ala Phe Ile Thr Glu  Asp Lys Thr Glu Leu  Tyr Met Leu 
              4160                 4165                 4170             
          Phe Ile  Asn Cys Leu Glu Asp  Ser Ile Leu Glu Lys  Thr Ser Ala 
              4175                 4180                 4185             
          Tyr Ser  Arg Asn Asp Glu Leu  Asn His Leu Glu Glu  Glu Gly Arg 
              4190                 4195                 4200             
          Phe Leu  Lys Ala Tyr Ser Pro  Ala Ser Arg Gly Arg  Glu Pro Ala 
              4205                 4210                 4215             
          Asn Glu  Ala Ser Val Glu Tyr  Leu Gln Glu Val Ala  Arg Ile Arg 
              4220                 4225                 4230             
          Leu Cys  Leu Asp Arg Ala Ala  Asp Phe Leu Ser Glu  Pro Glu Gly 
              4235                 4240                 4245             
          Gly Pro  Glu Met Ala Lys Glu  Lys Gln Cys Tyr Leu  Gln Gln Val 
              4250                 4255                 4260             
          Lys Gln  Phe Cys Ile Arg Val  Glu Asn Asp Trp His  Arg Val Tyr 
              4265                 4270                 4275             
          Leu Val  Arg Lys Leu Ser Ser  Gln Arg Gly Met Glu  Phe Val Gln 
              4280                 4285                 4290             
          Gly Leu  Ser Lys Pro Gly Arg  Pro His Gln Trp Val  Phe Pro Lys 
              4295                 4300                 4305             
          Asp Val  Val Lys Gln Gln Gly  Leu Arg Gln Asp His  Pro Gly Gln 
              4310                 4315                 4320             
          Met Asp  Arg Tyr Leu Val Tyr  Gly Asp Glu Tyr Lys  Ala Leu Arg 
              4325                 4330                 4335             
          Asp Ala  Val Ala Lys Ala Val  Leu Glu Cys Lys Pro  Leu Gly Ile 
              4340                 4345                 4350             
          Lys Thr  Ala Leu Lys Ala Cys  Lys Thr Pro Gln Ser  Gln Gln Ser 
              4355                 4360                 4365             
          Ala Tyr  Phe Leu Leu Thr Leu  Phe Arg Glu Val Ala  Ile Leu Tyr 
              4370                 4375                 4380             
          Arg Ser  His Asn Ala Ser Leu  His Pro Thr Pro Glu  Gln Cys Glu 
              4385                 4390                 4395             
          Ala Val  Ser Lys Phe Ile Gly  Glu Cys Lys Ile Leu  Ser Pro Pro 
              4400                 4405                 4410             
          Asp Ile  Ser Arg Phe Ala Thr  Ser Leu Val Asp Asn  Ser Val Pro 
              4415                 4420                 4425             
          Leu Leu  Arg Ala Gly Pro Ser  Asp Ser Asn Leu Asp  Gly Thr Val 
              4430                 4435                 4440             
          Thr Glu  Met Ala Ile His Ala  Ala Ala Val Leu Leu  Cys Gly Gln 
              4445                 4450                 4455             
          Asn Glu  Leu Leu Glu Pro Leu  Lys Asn Leu Ala Phe  Ser Pro Ala 
              4460                 4465                 4470             
          Thr Met  Ala His Ala Phe Leu  Pro Thr Met Pro Glu  Asp Leu Leu 
              4475                 4480                 4485             
          Ala Gln  Ala Arg Arg Trp Lys  Gly Leu Glu Arg Val  His Trp Tyr 
              4490                 4495                 4500             
          Thr Cys  Pro Asn Gly His Pro  Cys Ser Val Gly Glu  Cys Gly Arg 
              4505                 4510                 4515             
          Pro Met  Glu Gln Ser Ile Cys  Ile Asp Cys His Ala  Pro Ile Gly 
              4520                 4525                 4530             
          Gly Ile  Asp His Lys Pro Arg  Asp Gly Phe His Leu  Val Lys Asp 
              4535                 4540                 4545             
          Lys Ala  Asp Arg Thr Gln Thr  Gly His Val Leu Gly  Asn Pro Gln 
              4550                 4555                 4560             
          Arg Arg  Asp Val Val Thr Cys  Asp Arg Gly Leu Pro  Pro Val Val 
              4565                 4570                 4575             
          Phe Leu  Leu Ile Arg Leu Leu  Thr His Leu Ala Leu  Leu Leu Gly 
              4580                 4585                 4590             
          Ala Ser  Gln Ser Ser Gln Ala  Leu Ile Asn Ile Ile  Lys Pro Pro 
              4595                 4600                 4605             
          Val Arg  Asp Pro Lys Gly Phe  Leu Gln Gln His Ile  Leu Lys Asp 
              4610                 4615                 4620             
          Leu Glu  Gln Leu Ala Lys Met  Leu Gly His Ser Ala  Asp Glu Thr 
              4625                 4630                 4635             
          Ile Gly  Val Val His Leu Val  Leu Arg Arg Leu Leu  Gln Glu Gln 
              4640                 4645                 4650             
          His Gln  Leu Ser Ser Arg Arg  Leu Leu Asn Phe Asp  Thr Glu Leu 
              4655                 4660                 4665             
          Ser Thr  Lys Glu Met Arg Asn  Asn Trp Glu Lys Glu  Ile Ala Ala 
              4670                 4675                 4680             
          Val Ile  Ser Pro Glu Leu Glu  His Leu Asp Lys Thr  Leu Pro Thr 
              4685                 4690                 4695             
          Met Asn  Asn Leu Ile Ser Gln  Asp Lys Arg Ile Ser  Ser Asn Pro 
              4700                 4705                 4710             
          Val Ala  Lys Ile Ile Tyr Gly  Asp Pro Val Thr Phe  Leu Pro His 
              4715                 4720                 4725             
          Leu Pro  Arg Lys Ser Val Val  His Cys Ser Lys Ile  Trp Ser Cys 
              4730                 4735                 4740             
          Arg Lys  Arg Ile Thr Val Glu  Tyr Leu Gln His Ile  Val Glu Gln 
              4745                 4750                 4755             
          Lys Asn  Gly Lys Glu Arg Val  Pro Ile Leu Trp His  Phe Leu Gln 
              4760                 4765                 4770             
          Lys Glu  Ala Glu Leu Arg Leu  Val Lys Phe Leu Pro  Glu Ile Leu 
              4775                 4780                 4785             
          Ala Leu  Gln Arg Asp Leu Val  Lys Gln Phe Gln Asn  Val Gln Gln 
              4790                 4795                 4800             
          Val Glu  Tyr Ser Ser Ile Arg  Gly Phe Leu Ser Lys  His Ser Ser 
              4805                 4810                 4815             
          Asp Gly  Leu Arg Gln Leu Leu  His Asn Arg Ile Thr  Val Phe Leu 
              4820                 4825                 4830             
          Ser Thr  Trp Asn Lys Leu Arg  Arg Ser Leu Glu Thr  Asn Gly Glu 
              4835                 4840                 4845             
          Ile Asn  Leu Pro Lys Asp Tyr  Cys Ser Thr Asp Leu  Asp Leu Asp 
              4850                 4855                 4860             
          Thr Glu  Phe Glu Ile Leu Leu  Pro Arg Arg Arg Gly  Leu Gly Leu 
              4865                 4870                 4875             
          Cys Ala  Thr Ala Leu Val Ser  Tyr Leu Ile Arg Leu  His Asn Glu 
              4880                 4885                 4890             
          Ile Val  Tyr Ala Val Glu Lys  Leu Ser Lys Glu Asn  Asn Ser Tyr 
              4895                 4900                 4905             
          Ser Val  Asp Ala Ala Glu Val  Thr Glu Leu His Val  Ile Ser Tyr 
              4910                 4915                 4920             
          Glu Val  Glu Arg Asp Leu Thr  Pro Leu Ile Leu Ser  Asn Cys Gln 
              4925                 4930                 4935             
          Tyr Gln  Val Glu Glu Gly Arg  Glu Thr Val Gln Glu  Phe Asp Leu 
              4940                 4945                 4950             
          Glu Lys  Ile Gln Arg Gln Ile  Val Ser Arg Phe Leu  Gln Gly Lys 
              4955                 4960                 4965             
          Pro Arg  Leu Ser Leu Lys Gly  Ile Pro Thr Leu Val  Tyr Arg His 
              4970                 4975                 4980             
          Asp Trp  Asn Tyr Glu His Leu  Phe Met Asp Ile Lys  Asn Lys Met 
              4985                 4990                 4995             
          Ala Gln  Asp Ser Leu Pro Ser  Ser Val Ile Ser Ala  Ile Ser Gly 
              5000                 5005                 5010             
          Gln Leu  Gln Ser Tyr Ser Asp  Ala Cys Glu Val Leu  Ser Val Val 
              5015                 5020                 5025             
          Glu Val  Thr Leu Gly Phe Leu  Ser Thr Ala Gly Gly  Asp Pro Asn 
              5030                 5035                 5040             
          Met Gln  Leu Asn Val Tyr Thr  Gln Asp Ile Leu Gln  Met Gly Asp 
              5045                 5050                 5055             
          Gln Thr  Ile His Val Leu Lys  Ala Leu Asn Arg Cys  Gln Leu Lys 
              5060                 5065                 5070             
          His Thr  Ile Ala Leu Trp Gln  Phe Leu Ser Ala His  Lys Ser Glu 
              5075                 5080                 5085             
          Gln Leu  Leu Arg Leu His Lys  Glu Pro Phe Gly Glu  Ile Ser Ser 
              5090                 5095                 5100             
          Arg Tyr  Lys Ala Asp Leu Ser  Pro Glu Asn Ala Lys  Leu Leu Ser 
              5105                 5110                 5115             
          Thr Phe  Leu Asn Gln Thr Gly  Leu Asp Ala Phe Leu  Leu Glu Leu 
              5120                 5125                 5130             
          His Glu  Met Ile Ile Leu Lys  Leu Lys Asn Pro Gln  Thr Gln Thr 
              5135                 5140                 5145             
          Glu Glu  Arg Phe Arg Pro Gln  Trp Ser Leu Arg Asp  Thr Leu Val 
              5150                 5155                 5160             
          Ser Tyr  Met Gln Thr Lys Glu  Ser Glu Ile Leu Pro  Glu Met Ala 
              5165                 5170                 5175             
          Ser Gln  Phe Pro Glu Glu Ile  Leu Leu Ala Ser Cys  Val Ser Val 
              5180                 5185                 5190             
          Trp Lys  Thr Ala Ala Val Leu  Lys Trp Asn Arg Glu  Met Arg 
              5195                 5200                 5205         
          <![CDATA[<210>  2]]>
          <![CDATA[<211>  235000]]>
          <![CDATA[<212>  DNA]]>
          <![CDATA[<213>  Homo sapiens]]>
          <![CDATA[<400>  2]]>
          acccaggagg tggaggttgc agtgagccaa gatcgcgcca ctgtactcca gcctgggtta     60
          cagagtgaga ctctgtctca aaaaaaagaa aaaaaagaaa aagaaaagaa aaagaccaca    120
          cattaatcca ggactgtggg gctcctccca ggaggaggtg gccctgaccc ctgacctgta    180
          tgcttcctgg gaaatgtgct tctggggagg acagagggag gaggaaggag agggaggaag    240
          aggaaggcag gggagagaag ggaggcatta caggaggctt tgagcccagg ggaagagggg    300
          ttttccctct ggtctggtgg gtccggcacg gaggcggggg gagagcatga tgggagcaca    360
          gtgggaaggg gacccaggtt tacctccggg tcaggagcct ggctgtggtc tggcatggag    420
          gcagggggag ggcatgatgg gagcacagtg ggaaggggac ccaggtttac ctccgggtca    480
          ggagcctggc tgtggtctgg catggaggca gggggagggc atgatgggag cacagtggga    540
          aggggaccca ggtttacctc cgggtcagga gcctggctgt ctcctgtgtc taaggaacag    600
          gcccgggagt ctgcagggcc cctctctggg gcgtgctttt ccccctcagt ctcctgggca    660
          cagcctgggg acctgctcat tggcaggaca gaggctgcct gggctttcgg gggagcacac    720
          agatgccgtt ccctccctcc ctcttttctc ccgtatctcc cacgttcagg gtgaacccag    780
          aaaaccctgg ggaatggaag tgctttggga atgtgggctt ctgccaaggc ctgtggtccc    840
          tccatcgtag ccactccttg agcagcctgt gccagcaggg aggagaggag ggggtgcagc    900
          atctcgccgg gaacctgagt ccacagccga ggatgactga ccctccctct tgtgtgacaa    960
          caggattctg caggacagag agatgaaact ggaaataatt cagtccaaac agtcttccaa   1020
          gggacccttg ctgctacgaa aaggtggctc cgagaagttt ttacaaagaa catgctcaca   1080
          tcttcaggtg cctcattcac atacgtcaag gaaattgagg taggcatttg gccgaaggct   1140
          tctgggtagg gatgtgactg atcgtgattc ctcatggcct caaatcatgg ggtacaggct   1200
          gctggccagg ggcagttgtt ggccttcacc tgagcctcag ttcttcatct acaaaatgga   1260
          gttgctcctg tctacctggc agggtggctc tgaggcagac agatgccggg tgcaaagtgc   1320
          tgctgcactg cctcgtgtcc cctggccggg cacagtccct gtggtgatgg aggtgtggag   1380
          gtgatggtga tggttggtgg tggtggtggt agaggtgatg gtggtggagg tgatggtgat   1440
          ggttggtggt ggtggtggta gaggtgatgg tggtgaaggt gatggtgatg gtggacgtaa   1500
          tggaggtgat ggtggtgatg gtggtcatgg aggtggtgga ggtgatggtg gtggtggagg   1560
          tgatggtgat tgtggtggag gtgatggtgg tgatggtgat ggttgtggag gtgatggtgg   1620
          aggtaatgga ggtgatggtg gtggtgaagg ggatggtggt gatggaggtg gtggtggtgg   1680
          aggtgacaat ggtgatgctg gtggtggagg tggtggaggt actggaggtg atggtggtgg   1740
          tgaaggtgat ggtggaggta atggaggtga tggtggtggt ggaggtgatg gtggaggtac   1800
          tggaggtgat ggtggtggtg aaggtgatgg tggaggtact ggaggtgatg gtggtggtgg   1860
          tggtgatggt ggaggtggtg gaggtaatgg aggtgatggt ggtggtggag gtgatggtgg   1920
          aggtactgga ggtgatggtg gtggtgaagg tgatggtgga ggtaatggag gtgatggtgg   1980
          tggtggtggt gatggtggag gtggtggagg taatggaggt gatggtggtg gtggaggtga   2040
          tggtggaggt actggaggtg atggtggtgg tgaaggtgat ggtggaggta ctggaggtga   2100
          tggtggtggt gtaggtgatg gtggaggtga tggtggtggt gaaggtgatg gtggaggtaa   2160
          tggaggtgat ggtggtggtg aaggtgatgg tggaggtact ggaggtgatg gtggtaaagg   2220
          tgatggtgga ggtactggag gtgatggtgg tggacgtgat ggtggaggta atggaggtga   2280
          tggtggtggt ggtggtggtg gaggtactgg aggtgatggc ggtcgtggag gtgatggtgg   2340
          aggtaatgga ggtggtggtg gtggtggtgg tggaggtact ggaggtgatg gtggaggtaa   2400
          tggaggtgat ggtggtgatg gtgatggtgg aggtactgga ggtgatggtg gtggtggtgg   2460
          aggtaatgga ggtgatggtg gtggtgaagg tgatggtgga ggtaatggag gtgatggtgg   2520
          tggtggtggt ggtggtggag gtaatggagg tgatggtggt ggtggtggtg gtggtggagg   2580
          tactggaggt gatggcggtc gtggaggtga tggtggaggt aatggaggtg gtggtggtgg   2640
          tggtggtgga ggtactggag gtgatggtgg aggtaatgga ggtgatggtg gtgatggtga   2700
          tggtggaggt actggaggtg atggtggtgg tggtggaggt aatggaggtg atggtggtgg   2760
          tgaaggtgat ggtggaggta atggaggtga tggtggtggt ggtggtggtg gtggaggtaa   2820
          tggaggtgat ggtggtggtg gaggtgatgg tggaggtact ggaggtgatg gtggtggtga   2880
          aggtgttggt ggaggtactg gaggtgatgg tggtcgtgta ggtgatggtg gaggtgatgg   2940
          tggtggtgaa ggtgatggtg gaggtactgg aggtgatggt ggtggtgaag gtgatggtgg   3000
          aggtaatgga ggtgatggtg gtggtgaagg tgatggtgga ggtaatggag gtgatggtgg   3060
          taaaggtgat ggtggaggta ctggaggtga tggtggtaaa ggtgatggtg gaggtaatgg   3120
          aggtgatggt ggtggacgtg atggtggagg taatggaggt gatggtggtg gtggtggtgg   3180
          aggtactgga ggtgatggtg gtggacgtga tggtggaggt aatggaggtg atggtggtgg   3240
          tggtggtgga ggtaatggag gtgatggtgg tggtggtgat ggtggaggta ctagaggtga   3300
          tggcggtcgt ggaggtgatg gtggaggtaa tggaggtgat ggtggtggtg gtggtggtac   3360
          tggaggtgat ggtggaggta atggaggtga tggtggtggt ggtggtggta ctggaggtga   3420
          tggtggaggt aatggaggtg gtggtggtgg tggtggtgga ggtactggag gtgatggtgg   3480
          aggtactgga ggtgatggtg gtcgtggagg tgatggtgga ggtaatggag gtgatggtgg   3540
          tggtggtggt ggtactggag gtgatggtgg tccgtggagg tgatggtggt ggtggtaatg   3600
          gaggtgatgg tggtggtact ggaggtgatg gtggtggtga aggtgatggt agaggtaatg   3660
          gaagtgatgg tggaggtact ggaggtgatg gtggtggtgg tggaggtgac agtggtgatg   3720
          ctggtggtgg tggtggtggt ggtggtggtg gtggaggtgg tggtggtggt ggtggtggtg   3780
          atggtgatgg tggtggtggt ggtggtggag gtgatggtgg aggtaatgga ggtgatggtg   3840
          gtggtgaagg tgatggtggt gatggaggtg gtggtggtgg aggtgacagt ggtgatgctg   3900
          gtggtggagg tggtggaggt actggaggtc atggtggtgg tggaggtgat agtggtgaag   3960
          gtgatggagg tggtggaggt tatggagata atggtggtgg tggaggtgat agatatttga   4020
          acatgcctga cctaagaaaa gttcattttc atttttggct gggcactatg gctgatgcct   4080
          gtaaccccaa ctctttagga agcctaggtg gaagggtggc ttgaacccag gaggtcaggg   4140
          ctgcagtgag ctatgactgt gccactgcac tccaacccag gtgacggagc gagaccctgt   4200
          ctcttaaaat atttttttta cagtgcattt tcatgtgttt caacctccta gtgtccctgc   4260
          caaaaatatt ttaatctgaa tcaaatcatg gggaaattat gagacaaatc aggtcaaaag   4320
          acagtttaca aaacagttgg cctgaacttt tcaaaactgt caacatgtta aaagaaaaaa   4380
          gaaaaaaatg accagggaac tcttctagaa aagagatgtg ataagtaaat gcagaaaaga   4440
          gacgtgataa gtaagtacag cgtgtgtccc aggaggatct aggatccagt caggacagga   4500
          gctggagcac gagaggaacg ggggtggaga ccacttcctg ggggcagagt gtcctcctct   4560
          ccacgttgca cgtcctgagt gggaaacctg cactggagtt gcacagggaa gggctagggt   4620
          cttaggagac cctgcccagg tatgtagtgg caaggtgcca tgatgcctgc aacttacttt   4680
          ccaacggttt gggagagaaa atgctcattt gtgcagagtc cgaagaggga gcacagagga   4740
          gagaggaaga gtgaaagcag ctgtgygaag cgtgaatcgc acaggactgg agttgaatga   4800
          atgtgggtgg tggtgtgcta ttcttgcgac ctttttgaaa gttcaaaaat tttcaaagta   4860
          taacatgaga gataagtcct ttcagaataa aaagccggtt gtgcagtagg aggaccagta   4920
          gtggcccctg gttgggtctc tgattctaga aagccaacct gggctgctgt gaccggccac   4980
          tagcatggct gactgttgat gaaggttggg gagagccctg gtgttcgcgg agtcccgcgc   5040
          tctctgtatt gccgtaatgc tctgtctttc tcctttcatg ggagtgtgcc gtggcattta   5100
          gtcgtgagag tgggtgtgac ctgtgtgcgg gttttgcagg tctggaggcg gctggtggaa   5160
          atccaattcc ccgcggagca tggctggaag gagtcgttgc tgggagacat ggaatggagg   5220
          ctcacaaagg taccaaaagt ttgggggcag tcttttcagg gcgtgaaggc aagctggaga   5280
          accccagacc attagcgaca gccaagagat ctcagcagtg cctctctgtg ggcagggatg   5340
          gggtgaatca cagctccgtg tttctgtttc tgatccagcc cttatagtct gtccctagaa   5400
          gagcgcttcg gagtcttact gagaggacag agaagaacaa gggcccagga tctcaccatc   5460
          atgggggtgc gggatttttc ctgacccctt cgttggactt gcgacaggga tgctgtgttt   5520
          acttggcccg ccgtgctcaa ccccttgtgg gagggagcac gtgagtgagt gtggcatctg   5580
          gccagctgct ttgggagctg gcaggagcaa gctccgtgca ggccctgcag cagtgcccag   5640
          attgaggtgc ctgcaacccc cgaagctcca gagggcatgt tacagtgctc tcttagctcc   5700
          gccgtctatg gacagtagtg tgttatcagc tcagtgggtc ccttgccttg ttgcctaggg   5760
          tggctgccct ctgccagggc caatgtgaca gcctctttta ggtacccaca ctcggtgggt   5820
          cccaagctct tgtccagcat ccaagaagaa tggggtcacc cggacacttg aaggatggtg   5880
          aaggtggaga attttattaa gcaatggaaa tggctctcca tggagagggg agctggagag   5940
          gggatgggtc aggtggggaa tcttcctctg gtccaggtgt ctggctggct cttccctgaa   6000
          gtcaggacgt ctttccgaag ttaaaccgtc tctccttgga agtccagcca tccctctgaa   6060
          gtcaagtcac ctgtttccag tgaagctact tctctctcac taccaagtct ggggtcttta   6120
          taggcacaag atagggggca gggtgggccc taggtagttt tggaaaaagc aacattctat   6180
          tggtaaaaag acattactcc gaaagaacca gtggggagag agtaggcaca cggggataga   6240
          ggttctcact ttgggccatg ggtttcaggc ttttcggctc gaaggtgggg ttttgccagg   6300
          gacccgcccc tgtctgcgta ggatttctct gcctcctgcc tccatcaatg gggccccagg   6360
          cacaggaggg gccaggcctg cccataggca ggaagtctaa gtggcctgtt ggtgacagga   6420
          acctcatgac acacaagtgg agaacacaca gacatgcccc tcatgctgaa ttaaggcctg   6480
          aggctcaagg aaaattagtt tttatgtgat atgagagttt tatatgtaac tttttttttt   6540
          tttgagacgg ggtctcgctc tatcgcccag gctggagtgc agtggcggga tctcggctca   6600
          ctgcaaactc cgcctcccgg gttcacgcca ttctcctgcc tcagcctccc gagtagctgg   6660
          gactacaggc gcccgccacc gcgcccagct atatttttgt attttttgta gagacggggt   6720
          ttcaccgtgt tagccaggat ggtctcgatc tcctgacctc gtgatccacc cgcctcagcc   6780
          tcccaaagtg ctgggatgac aggcgtgagc caccgcgccc ggcctatatg taactgttaa   6840
          atggatcttt aaagggaaaa gtcagaaaca aggaaaaatg acctatgtct cataacttac   6900
          ctgtttttgc aagccaggtg ctttttctgc agagtgggaa aagagactct tttaaatttt   6960
          agcctttggt ctactggtgg ggggcaggga ggacatgctt tgcgtgggcc aggagaagct   7020
          taaaattggg ggaaacagta aaacagcagg aaagtaaaaa tgatgaaaga attttcatcc   7080
          catagagcac tggagcgctg catccgaaag ctctgaaacc accccccttt gatttttgca   7140
          ggaggaaccc ctctcccaga tcactgccta ctgcaatagt tgctgggaca ccaaaggctt   7200
          agaggacagt gtggccaaga ccttcgagaa atgcatcatt gaagccgtga gctcagcctg   7260
          ccaggtgaac aatctctcct cctgggaaac ggattcgggc tcacagctgt gttctgccat   7320
          gacccagcta agggctatga agcacccgct gggtctcagc tcctccgcta actcagagat   7380
          tgggaagtgg gcaccctcct ccctcgccaa gggcaatggc gctgaaatct agttctctcc   7440
          ggattcctca gtgtgctgca cagtccctgc tgctcgcacc atcctgcatg tgttccatat   7500
          ggaatcacgg ccgtgcgcgt gtggcacaag tcacacgggc ttgcaggccg ttcctcagat   7560
          ggccctgtca tcactgtggc tgctggtttg attgattgtt aacacttgct cagtaggtgt   7620
          gcgggaagag actccaaagg ttgacagaac atttatggaa gcaaaatatg tgaaatggaa   7680
          aattgtatca atttatttag ctcttttcgg caaaggggaa gagattgtgc ccccctgtct   7740
          cccaggaaca gtctcgcagg caatgccaca tgaggaagct ccctgctggc cacggctgcc   7800
          ctgctcacat ttcctaattg gacacttaac ccctgtacaa gcacagcctt gcggccacag   7860
          gggaagtcca gaaacattga ggtcattgaa ttccggggac caaggggttc taatttttta   7920
          agtgactgat acctttgata aggttttcct ttcccttttt cgttaactct ttgttgagat   7980
          attgttcgta tgccatacgg tacatctgtc aaaagttcca gttcagcagg ttttggggta   8040
          gtcacagata tgtacagtca tcaccacagt taatgacaga gcattttcat cacttcaaag   8100
          agaaacccgg cccctttagc catcatcctc ctcccctcta gtcacccact cccctctgca   8160
          ggcataaaca attgctgaac ataaacaact gcttctgtgg ctttctctgt tctgactgtc   8220
          atatgaatgg aatcatatca tatgtggcct tttgggtatg gcttatttca ctgagcataa   8280
          tgtttttttg ttgttggtgg tggtggttgt ttgttgtttt tgagacagag tttcactctt   8340
          tttgcccagg ctggagtgca atggtgcgat cctggctcac cgcaaccgct gcctcccggg   8400
          ttcaagtgat tctcctgcct cagcctccca agtgctggaa ttacagctac tttttgttta   8460
          aagagtcttt taattgttta aagaacaatg tgccgccaca ctcggttcct tttgtatttt   8520
          tagaagagac agggtttctc catgttggtc aggctggtct cgaactcccg acctcaggtg   8580
          atccacccac cttggcctcc cgaagtgccg agattacagg tgtgagccac cgcgcccggc   8640
          cgagcataat gttttgaaag accgctcagg ctggacacgg ttgctcacgc ctgtaatcac   8700
          ggcactttgg gagcccagga gttcaagaca agcctgggta acagagtaag accctgtctc   8760
          tataaaaact aaaaaataaa caaaaaaaat tagccaggca tggccgggca cacctgtggt   8820
          cccagctact tgggaggctg aggtgggagg ctcccttggg cccagaaggt caaggcagca   8880
          gtgagccatg atcacaccac tgcacttcaa cctgggggac agagcaagac cctgtctcaa   8940
          aaagcaataa caacaaaagt ccatccatat tgtagcttgt gtccgtttac gttaagtatt   9000
          ccttacccaa aatgcttgag accagaagtg ttttggattt cagatgtttt caaattttgg   9060
          aatatttgca tttacataat gagatgtctt ccagatggga cccagagtct aaccacaaaa   9120
          ttcacttgtt tcatatacat cttatacaca tagcctgaag gtaattttat acaatatttt   9180
          taacaatttt gtgcatgaga caaagtttgt attaagtatt tgtatgttga atttttcact   9240
          tgtggcatca ttatactcaa aaagtttgga ttttgtagta ttttggattt ggggattagg   9300
          aatgctcaac ctatatttca tttttttcca tggccaaata ttccccgttt atccatgtgt   9360
          ccattgacgg ccatctatgt tgcttcttcg gctattataa atctgctgat acaaacatta   9420
          gtgtacatat ttatgtgtgg gtgtatgtct tcatttctcc tgggtgtata cctcgatgta   9480
          gaattgctga atcatatggt aactccatgt ttaattgttt aaagaactgt ccggccgagt   9540
          cccacagcag ctgaaccatt ttcaatccct ccagcagcat aggaggcttc caggttctcc   9600
          acatcctcac taacatgtgt tgtctaactt tttgattcta gccatcctgg tgggtatgaa   9660
          gtggtatctc cttgtggttt ttgtttgttt tttgagatgg agtcttgccc tgtcacccag   9720
          gctggagtgc agtggcgtga tcttggctca ctgcgacacc tccacctcct gggttcaagc   9780
          aattctcctg cctcagtctc tcgagtagct gggactacag gcatgtgcca ccatgcccag   9840
          ctaatttttg tatttttggt agagacgggg ttttgccgtg tgggtcatga tggtctcgat   9900
          ctcttgacct catgatccac atgccttggc ctcccaaagt gctgggatta caggcgtgag   9960
          ccactgtgcc cggcctcatt gtggttttta actgcatttc tctgataact aatgatatca  10020
          agcatctttt catatgctta ttggatttgt ctgtatcttc tttggagaaa tgtttattga  10080
          gatattttgc ccctcatccc ccccaccccc cctttttttt tttttttttt gagaaaaggt  10140
          ctcgctttgt cacccaggct ggaatacaat ggcacgatca cagctcacta cagcctcaac  10200
          ctcctgggct gaagtggtcc tcccacttta gcctcccgag tagcagggac tacaggcatg  10260
          tgccaccatg ttcagctaat taaaaaaaaa atttctgtgg gccgggcatg gtggctcatg  10320
          cctgtagacc atcctggcta acacggtgac accctgtctc tactaaaaat acaaacaatt  10380
          agctgggcat ggtggcatgt gcctgtagtc ccagctgctt gggaggctga ggccagagaa  10440
          tcacttgaag ccatgaggtg gaggttgcag tgagctgaga ttgtgccact gcactccggc  10500
          ctgggcgaca gagcgagact ctgtctcaaa aaaaaaaatt ttttttcgta gagacagggt  10560
          cttgagatgt tgcccaggct ggtcttgaac tcctggactc acatgaacct ccctccttgg  10620
          ccttccaaag tgttgggatt gaaggcatga gccaccgcac ctggcctctt ttgctcattt  10680
          ttaaattggg ttgtcttttt attatagagt tgggagtctt tattctatat acaagtcact  10740
          tgtcagatat atgattgcaa gtattttctc ccattctatg tgttgttttt tcacattctt  10800
          attggtttct tttgaagcac agaagtcttt aattttgaag aagttagcat atctgttttt  10860
          tcttttgttg cttgtacttt tggtgtcaaa gaatcctttg ccaaatccta ggtgatgaag  10920
          atttactcct atgtttattt atctctaaat gttttatagt tttagctctt acatgtaggc  10980
          ctttgatcca ttttgagttc ctttttatat atggtgtata tggtgtgagg taagggttct  11040
          gtttcattct cttgcatgtg gacatccagt tgtcccagca tttgttgaaa ggactctaca  11100
          ttccctgttg agtgatgttg gcactcttgt caaaaatctg ttgacgatac atgtatggat  11160
          ttatttctag attttcaatt ctatgtggtg atctacttgc ctatccttgt gtcagtacca  11220
          cactgtttgg actaccattg ctttctagta agttttgaaa ttgggatgtg tgagtcctcc  11280
          tactttgttc ttatttttca agattgtttt ggctattttg ggtcccttgc aatttcataa  11340
          gaattttaga atcagtatgt cagtttccac tgacaaggaa gtcagctggg attctggtag  11400
          ggctggtatt caatgtatag atcagtttgg agagcattgc catcttaaca aggttaagtt  11460
          ggatttcttt cattcaatta gatttttttt tttcccctgt tagacagagt ctcgccctgt  11520
          tgcccaagct ggagtgccca agtagctggg actacaggtg tccaccacca tgcctggcta  11580
          atttttgtat ttttagtagt ttcaccatat tggtcagggt ggtctcgaac tcctgacctc  11640
          agatgatcaa cccgccttga cctcccagag tcctgggatt acaggcatga gccaccattc  11700
          ctggccaatt tcttttaaca atgttttgta tttttcatag tttaaatttt gcacttcttt  11760
          tgttaaattt ctaagtactt ttttttgggg gggggtgcta ttgtaattgg aattgttttc  11820
          tgaattctgt ttccagattg ttccttgctg gtgtctagac acacagtgct ccatgcgtct  11880
          tgtatcctgc aacattgctg agctcatttg gtagctcaaa ttgtgtgtgc gtgtgtgtgt  11940
          gtgtgtgcat gagagagaga attaaatttt ctatacataa gatcatatca tctgtgaata  12000
          gagtttcact tcttccaatc tggatgcctt ttatttcttt ctcttgcata actgccctgg  12060
          ctagaacctc cagtacaatg ttgaatgaaa gtattgaaag tggacatctt tgtcttgttc  12120
          tgatcttaag agaaggtttc agtcttttgc caccaggtgt gatgtcaacg tgagcttttc  12180
          atagatgccc tttatcagtt tgtggaagtt cctttttgtt cctcatttgt tgaatgcttt  12240
          tttttcttta atcatagaag agagttggat tttgtcaaat gcttttcccg tatctactga  12300
          aatgatcatg cgatattttc ctaatgttat taactgatat ttgatgttaa atcaaccttt  12360
          catccctgag ataaattaca cttgatcgtg gtgtatagtt cctttaacat ggggctggat  12420
          aaggttttct tttatccttt taaatgtcag aaagtatcta ttataaatta accttgtggt  12480
          ttttactaat tactgaaatg ttttacagaa actttgaacc taaaggaaga aaaatattgt  12540
          ttctcggagg agaattaaaa agagaattaa aatgtatatg ttgtttgtag gcagcttttt  12600
          aaaagaatta tggtttagga acataaaata tatgctatat taagggttta ttcatttttg  12660
          gtatttttca tgatatgaaa gtccaaaaaa aaatgtagaa actggcagcc agaaggaagg  12720
          agggtgactg gttatgttgg tgtgtgtttg tgtgtgtgtc ttcacatctc tggtgctgga  12780
          cacttaagga ggcagtatac aaggaaatga aaattttcga agaaatgtaa agtgttttac  12840
          tattttgctc tttttgtggc cttataaaac aagttacagt agatttcaga aatgctatcg  12900
          agtaggtaat ttgcttttgt tatttcaaaa caaactaatg aaaaacttct aaatgtccct  12960
          cttttattaa ttttcttgta gtctcagacc agtatccttc aggggttctc ttactctgat  13020
          ttgcggaaat ttggcatcgt cttgtctgct gtgatcacta agtcctggcc taggaccgcg  13080
          gacaacttca atgacatttt aaagcatctg ctcacgttgg cagatgtcaa gcacgtcttc  13140
          agattgtgtg gtatgtttgc gggagtgctg ggaacatcag ctcaggcaag gtggtgtctt  13200
          cctgattggg aaaggtggga ggcagaagat ttgacatgat gatactgaat tgggatgggc  13260
          tgatgtttga caaaggctgc agtttggaca gagagaccct ggaaggctca gagtgtcttg  13320
          cgttgtaaat aataactaat gctaacagcc actattcatt gaatgcttgc tgtaccctag  13380
          cgactgtgct gggtcgcaag ggaagtgccc ttgaaacaac ccttctgaaa gtccccttta  13440
          aggcccccag ttttcagatc aggaaacaaa tggagaaggc aatgcgactt acctaaggtc  13500
          tcaaagatta taagtagtaa aaactaaaat ccagacccag gtatgtctta tttggagatc  13560
          aatatagaat gtccaagcca acattgatga cctcaacaga aagtgaagta ctgtgctgtc  13620
          tgatttcccc ccagcccccc gcgccccagg tgttttgtgg tcaaggaggg agagagagag  13680
          acattccatc ctaaaaacgt tagagtccag ttggcgtgtg agaccttaga ttcatatctt  13740
          tcagtgagaa ggcgctggat gtggaacagc caaaatcaat gctgagcttc ctacacatca  13800
          gggaagctgt ggggatcaaa taactgaatt aatatgggag tgcacaagta aaagctactc  13860
          tcttgaaaag atcatttttg tgttatttgt atttatttat ttatttattt atttatttat  13920
          ttattttgga gatggagtct cgctctctca cccaggctgg agtgcagtgc tgtgatctca  13980
          gctcactgca acctctgcct cccgggttca agcgattctc ctgcctcagc ctcccaagta  14040
          gctgggatta cagatgtgag ccactgtgcc cagcagttta tttaatttta aaacaaggtc  14100
          ttctctgttg cgcaagttag catgtagtag agtgatgcca tcatcgctca ccgtaagcgc  14160
          tgacctcccg ggctcacgtg atcctcctgc ctcagcctcc caagtggctg gcactccagg  14220
          cgtgcaccac catacccagc ctgtttataa gttggataga attttttaga gcactttgat  14280
          gtgtacagaa aaattgagca gaaagtacag agagttgtca tctatctctg ccaccatcac  14340
          acgggcagta ccctgttagt aacatgcagc attagtgtgg tgcttttgtt acagctgaga  14400
          agccaatatt gataacactg ttattaacta aagtccatag ttcgttcctg gtgttgtcca  14460
          ttctctgagg tttggataaa ccatggcctg tgtccaccat tccagtatcg tgcagaatag  14520
          ttgcgctgcc cctacaaaat cccatgctcc acccctccca tttcctttag tcttttccag  14580
          aatgtcctat ggttggaatc ttataggatg tcgcctttag actggcttcc ttcacttagt  14640
          aatacgtatt tatgtttcct ccatgtcttt tcatggcttg agagctaact tcgttttacc  14700
          actgaataat attctattgt atggatgtgc taccattcgc ttacccgttc acctcatgaa  14760
          agacatcttg gttgcttcca agtttttgca atgattagta aagctactat gtttgtttct  14820
          tatggtgcag ataagcttca tcttctccta atattgtatg gctctaatat tactgggaga  14880
          gaaatcctaa gtggttaaac aaaacatgta taaaaattct gccctctaaa tttatcataa  14940
          aatcagttcc aagattttgc aagataatga agttgtacag agtataaagt tatcacatgg  15000
          ctgtttctct ctttgcatat gctatgaaag tgtctcccta agaccatcct gatagacatt  15060
          gctaggtatg tctgcatcct ctggtgcagt ttcttctgtt gtaggtattc ctagggcagg  15120
          ggctttttaa agaagattct gtgtattcta tttaaaaaat atactcaggc catgtgaggt  15180
          ggttcatgcg tataatccta atgttttggg aggccaaggc gggaggatct cttgagccca  15240
          ggagtttgag accagcctgg gcaacaaagt gagaccctgt tctctacaaa aaattttgaa  15300
          agtttgccag gcatggtgct gtgcacctgt gttcctagct actcgggagg ctgaggcagg  15360
          aaaatgaggt tacagtgggc tatggttgtg ccactgcact ccagcctggg tgacagagag  15420
          agaccctgtc aaaaaaaaaa aaaaaaggaa gtcagtccat ccgtatactg aaggggacgt  15480
          gggttttaac ctgagaaatg tgtctcccag ctgattttgg ccattgcggg aagtcatctt  15540
          cttggacaag gaagttgttc aggggatgaa tctgggcaag acctaaccct cgtgggggaa  15600
          agcagaaggg agtggaatga ttggcgcatc tggagacact ggccagccat tgcctgtgtt  15660
          tgaggaagtg ggggcagaac aagaggttat ctggaattcc cacggtaacg gcaaagaggc  15720
          aggaggtggg gagcccactg tgttaactgt gttcttcatc tattcaggaa ccgacgagaa  15780
          aatactagca aatgtcacag aggatgccaa gaggctgata gctgttgccg actctgtgtt  15840
          gacgaaagtt gttggtgacc tcctaagtgg cacgatttta gttggacaac tggagctgat  15900
          tataaagcac aagaatcagt ttcttgacat ctggcaactg agtaagcatc gagtcgatac  15960
          gcacttcagg ctcctgaggc attaagtagc tggaagacac gtttgtgttt gcgtgtgcat  16020
          ttttgtaaag gagataatca tcttagcctt gataatgagt atctcttctt gctcataagt  16080
          tgataggggt ggtttataat tctcaagaac atcacgggaa agtgataaaa taatggccat  16140
          ctcgaaaaag tgggtatgcg caaaaccatc ctagtccttc tcctggtggc ggggaaggtg  16200
          cggcgctttc aaagcattgc catggaaaat ggcatttgtt gctgtattgg gttactttat  16260
          tggtgttctt attttccagg ggaaaaaagt ctttcacccc aggatgaaca atgtgctgtg  16320
          gaggaagcac tggattggag aagggaggaa ctgttacttc taaagaaaga gaaaagatgt  16380
          gttgatagtc tcctgaagat gtgtgggaac gtgaaacatc tgatacaagg tggtattcct  16440
          gagaagtgaa caaagttgag ggctctcaaa gggttagagg agaacacagt aagaatggat  16500
          cacagtagca gatctttatt ttggagagaa ggctttaaaa tttttttttt aatttgcatt  16560
          tgctgggggg atcgctttca cctcttttag attcttcttt ttggtattta tgtccacatt  16620
          tccaaataac atgcttaagt gtctcctgga tttttccgga gtcagcatga gctgctgacg  16680
          cccgctgcag aagatgaggg cttagagcca cacatttctg gtctgtgccc tgcacacatc  16740
          acctttccac ctcctgttgc ttcctgtttt ctcataacgg agttgcatca ttgtttaggg  16800
          ttaaatcatc aggacccaca cggatcacaa gtgaaccacg aaagaaaccg tcatcatttt  16860
          acaatttttg cacaaactct ctgttttcca cagaattaca tttcctgtca gatgctgttt  16920
          tcactgcgtt aatgatacgc tgttttcatt gtattaattt ctaattccat cgcaatctct  16980
          gccgagtgtc tgaatttcct tgaagatcat tggtttgacc tttgaaaagg aacctgccaa  17040
          ccctgggctg cagacgtagg gtggagtctc cctccacctc ctaggagcct ttgcctggca  17100
          cctgggttag acgtggttcc cacgcccccc tcccccgcta ctcactcctg cttcctctgt  17160
          tggcagagca caccctcact ggcttcctga gaaaagggcg tgtaagaggt taaaccctcg  17220
          aatccttgtg tgtctaaaga tgtctgtcct cttactaggt cagtcgctcg gctaggtcta  17280
          gaattacaga ccggaagtca ttttccttct gaagtttcaa tgtgctgcgc catcattgcc  17340
          tccacagtgt ggctatgtat ggagaagtcc gatgcagtgc cagttacaca tccttcatgt  17400
          gtgtgacctg ttttctcttt cttgaagctc ttgagctctt tctgttactc atattctgaa  17460
          ataataacgt gtcttggcct ggatctatgt tccatcgagg ctgggcatgt tggctcccac  17520
          ctgtaatccc agcacttcag gaggccaagg caggaggact gcttgagtct aggagtttga  17580
          gaccagcctg ggcaacatag caagacccca tctctaaaaa aaatacaaaa aaattagcaa  17640
          gacacggtgg tgcatgcctg tattcccaac tacttgggag gctgaggcag gaggatcact  17700
          tgagcctggg aagtcgaggc tgcagtgagc cgaaatcacg ccacaacact ccagcttggg  17760
          tgacagagtg ggaccctgtc tcaaaaaata aaatattttc agtcccctct attgggtatt  17820
          aataggtagg tctttcaact ctagacatca aaatccttga gttctgggaa attctcttga  17880
          atgatttaat tttttcttct cttgctggaa ttcctgttaa ttggatatgg gacctcctgg  17940
          atgatcatct aactgtcatc atttttctct cggattttct atctctgttt tttgctctgc  18000
          tcttgagaga tttattcaga accaaacttt ctgcttaggt tttcatgtca gctttcgtat  18060
          atatatttaa tgtagaggaa ttctttttct cggaatgttc ctttttaaat tctgtcctgt  18120
          tcttgttcac gttgcagcat cttcccttct gggttattca ccgttttgtt ttggaggttt  18180
          tgcttttcct ggcatcatgt gctgcttcct ccaggttcct ttcacttgtt gatttgtttt  18240
          gattttcctc ctatgtctgg acattcttgt ttgtctgtgt ttattaagag aaagccctca  18300
          caagtgggtt ggccctctgc ggggtgctgc cgtggggtgc tgtggctcga cctggaagtt  18360
          ggcctgtctc ctgaagtctt ctgtctcctg cctggagggt gtgggcctgg ctgccaggtt  18420
          tctgggagcc aagagggaga agcgggctgg cgggccttgg catcccgtgc gtggtcctcc  18480
          catggcccgt gttctcagtg tggttctccg ccacctccct ctgtctcctg tgtttcacac  18540
          cccatcctcc ttccccctga gattggataa ttcatgtctt ctgttagctt cctgagaaag  18600
          gggatgtgtc tagaaaggcc ctttgttctg ccatgtatct gtggcctcca atccacacgc  18660
          ccccctgcgt tatcctttct agaaaatgaa ccatctcttg gctgctgggg tgaagaaggg  18720
          ggtccacctg ctgtgtcagg gcattggggt gacagttggt gtgctggatg gaccatgtct  18780
          tttttttggg acagagtctt gccctgttgt ccaggctgga gtgcagtggc tcagtctcgg  18840
          ctcactgcaa cctctgcttc ctgggttcaa gtgaatcttg tgtctcagcc tccctagtag  18900
          ctgagattac aggtgtccac caccacgtcc agctagtttt ttgtattttt agtggagatg  18960
          ggatttcatc atgttggcca ggctggtctt gaactcctga cctcaagtga tccatccgcc  19020
          tcagcctccc aaagtgctgg gattacgggc gtgagccact gtgcccagcc tggaccgtgt  19080
          cttaaacaga ctttgaaccc agtcttcctt atttcatcac cacctcccag tctgcagtga  19140
          cctgcacaat gtgtgtctgc tttttgggaa tcctgtgaca taaaactact cagctctcag  19200
          tgttgcccac tgggacccta ggactccatg ttaccaggcc tcatgtgtca tttaccactg  19260
          gttcagctcg ttttcaactt ctaaaatttt gttcctgtta tcctgttcgc cattcctcct  19320
          cctgtccttg tcagtttatg actttttttt ttttttttga tatggagtct cactctgtca  19380
          cccaggctgg agtgcagtga cacagtctca gctcactgca acctccacct cccaggttca  19440
          agtgattctc ctgcctcagc ctcctgagta gctgggatta caggtgcgct ccaccacgcc  19500
          tggctaattt ttgtattttt agtagagaca gggttttgtc atgttggcca ggctgctcat  19560
          gaactcctga cctcaggtga tccgcccatc tcagcgtccc aacgtgctgg gtgggattac  19620
          aggcatgagc cactgcgccc aactagttta tgacttttta aatgcaattt atgttctgtc  19680
          attggagtgg ggtttggcaa agagagtaaa taggtgcgtg ttttcccact gccatcttta  19740
          cccagaagtt tatgatgctt tctttatcat gaatattggt taacaaggcc aagcggggag  19800
          ggaaagacct gtgaactctt cctgagaaag aaatcctagc agctgtgtgc tcttgagttc  19860
          gctcagagaa gtgaggagag aaagtcttag gaaagtgaaa taaaatggaa tcatgattag  19920
          agctttgact tctgacactt tcttttcgct tctaaagtgg actttggagt gcttgcagta  19980
          agacactcac aagacctcag cagtaaaaga ttaaatgaca ccgtgacagt gagactgtcc  20040
          acctcctcga actcgcagag ggcaacgcat taccacctga gctcccaggt ccaagaaatg  20100
          gctgggaaga tagacttgct cagagacagc cacatcttcc agctcttctg gcgggaagcc  20160
          gcagagccgc tgagtgagcc taaggaggac caggaagccg cagagttgct gagtgagccc  20220
          gaagaagaat cagaaaggca catccttgag cttgaagagg tgtatgacta tttgtatcag  20280
          ccttcttaca gaaagttcat taagttgcac caggatctaa agtcaggaga ggtcaccctt  20340
          gcagagattg atgtcatctt caaggacttt gtgaataaat acacggacct ggattcagaa  20400
          cttaagatca tgtgcaccgt ggaccaccag gaccaaagag attggatcaa ggaccgagtc  20460
          gaacagatca aggaatacca tcacctgcac caggctgtcc acgcagccaa ggtcatcttg  20520
          caggtcaaag agagcctggg actgaacggt gacttcagtg ttctcaacac tttactaaat  20580
          tttgtaagtt atttgctggg gactgtgggg gtttggaggg gcgtcctgcc tcagcctctt  20640
          caggagccat gggctttgtg gctttgaaaa ggggggcgga tgacttagag cttccgtcag  20700
          gggctcctgt gtgtgtggta cttgaggcct gaatatccca agggctttgt ttttaccttt  20760
          gttataaata gtaccactgc tccttagcca gagggagttt ccttgggtct gcgtgaagat  20820
          caagaactca ggaaagggca acaatcctct tttcataacg ggcatttgta aagggtcata  20880
          ggctctctct aggttacaga agccaaaaag caaaacactt tgtcggctgc ccaactgcat  20940
          ctcccagttc cacccaaaag cggtaaatca gttgtttctg ttagagttaa gaggtgactc  21000
          ttttgctttt ttttttttga gatggagtct cgctctgtcg tccaggctgg agtgcagtgg  21060
          cgcgatcttg gctcactgca agcttcgcct cccaggttca cgccattctc ctgtctcagc  21120
          ctcccaagta gctgggacca caggtgcccg caaccacgcc cggctaattt ttttggtatt  21180
          tttttttttt tttagcagag acagggtttc accgtgttag ccaggatggt ctcgatctcc  21240
          tgacctcgtg atccacccac cgtggcctcc caaagtgctg ggattacagg cgtgagccac  21300
          cgtgcccggc tgagtcttct gcttcttatg tttttaggta gaccgagata atgattagaa  21360
          tttagctggg cacagtggct catgcctgta atcccagcac tttgggaggc tgaggtgggc  21420
          agatcacctg aggtgaggag ttcgagacca gcctgaccaa catggagaaa ccccatctct  21480
          actaaaaata caaaaattag ccgggtgtgg tgtcaggtgc ctgtaatctc agctactaga  21540
          gaggctgagg caggaggatc gcttgaacca cggaggcgga ggttgcagtg aaccgagatc  21600
          gtgccactgc actccagcct gggcgacaga gtgagactct tatctcaaaa aaaaaaacca  21660
          aaaaaaaaac ctggaatccc atccatttac acttgaaccc tagtgcacgt cctcgaggaa  21720
          gcaactgctc tgggccttta ttgacaaagc agaaaaagca acagtagtta cttggcaggg  21780
          ttatgtgagg aattgatttt aaaatccact ttattaaaat gcttagcaga atatcaggtt  21840
          cccaggaatc acagttcatc ttgatcaggg agaaacagcc atgggggttt gatcatccaa  21900
          ttcaggggta agagcttggt gtgcctgttg tcacagcagt ggcaaatcta ggcattgagg  21960
          gagggtgggg ctgctgggac ggtcagtgct tgcagctcac agattctggg gttctggtta  22020
          atgagttcca gtccacagta gagctttttc ttgcagactg ataacttcga cgactttcgc  22080
          cgtgaaacac tggaccagat caaccaggag ctcatccagg ccaaaaagct gctccaggac  22140
          atcagcgagg cccggtgcaa ggggctgcag gctctgtccc tgagaaagga gttcatctgc  22200
          tgggtccggg aggctcttgg aggtaaaatc agcctttggg gttgcgtgga agtgtggaga  22260
          aagttttcag atggcgcact gtgtggcgtt cctaaactct ttggcaatac ctccccttgg  22320
          ccaaggacta cgtaaagggc agaaagacgt tgcctgcatg ctttagggag atgggcactg  22380
          atcatagagt tcacaccggt acagtatttc ccatgtgctg ctgtaaaagc cactcacctt  22440
          gccacacccc gccacttcgg aagctgtaaa tggctcaggt tccttttcct taaaatcttg  22500
          cccccttcag ctttttcttc cagtagattt ttactggagg acaaggagag ttcctgccca  22560
          cagagaggtt tttttttttt gtttgtttgt ttttttgaga cagagtctcg ctctgtcgcc  22620
          caggctggag tgcagtggcg tgatcttggc tcactgcaag ctctgcctcc cgggttcacg  22680
          ccattctctt gcctcagcct cccgagtagc tgggactaca ggcgaccgcc accacgcccg  22740
          gctaattttt tgtgttttta gtagagacgg ggtttcactg tgttagccag gatggtctcg  22800
          atctcctgac ctcgtgatca gcccgtcttg gcctcccaaa gtgctgggat tacaggcatg  22860
          agccactgca cctggccttt tttttttttt gagacggagt ttcgctcttg ttgcccaggc  22920
          tggagtgcag tggtgcaatc tcggctcact gcaacctcca cctcctggat tcaagcgatt  22980
          ttcctgtctc agtctcctga gtagctggga ttacaggcgc ccgccaccac acccagctac  23040
          ttttttgtat ttttagtaga gatggggttt caccgtgttg gccaggctgg tcttgaactc  23100
          ctgacctcag gtgatccacc catctcagcc tcccaaagtg caggcgtgag caagtacagg  23160
          cgtgagccac cgcgcctggc cccacagaga gatttttctc acttctccat tgatgctgtg  23220
          cgtttcttgg cagcctcttc agttctgtgg cttagatgtc gttggcagag gagagaggaa  23280
          gaggcagagg aggcaggagg ggcacaggtg gcagtgcagg tgtgctcggg ggtctggggg  23340
          ccaccacctg ctggatctca ggctctggct ctcttgggag agccgctgct ttcagtggtg  23400
          gactctctgg tccacactga tgcacatcct tcagtgagta atttatctga ggggaatgat  23460
          ctgagtgttt catagttaat tgtgaacatg ttatttacag ctgagccttg gtttcttttt  23520
          gtttaaatgg taatgttgtg tggattgaag gaaagagcat acacagaagt gcagtacagt  23580
          gcctgggaca ttgaaattgc tcaggaacgg caagatatcg tttagtgcta ttaacagaca  23640
          gtacaggctg ggcgtggtgg ctcacacctg taatctcagc actttgggag gccaagtcgt  23700
          gtggatcacc tgaggtcagg agttggagac cagcctgacc aacatggtga aacctggtct  23760
          ctactaaaaa tacaaaaaat tagccaggcg tggtggtggg cgccagtaat cccagctaca  23820
          cgggaggctg aggcaagaga atcacttaaa cctggaaggt ggaggttgca gtgagccgag  23880
          atcatgtcac ttcactccag cttgggtgac agagtgagac tctgtctcaa aaaaaaaaaa  23940
          aaaaactaca aaagattagg tgttccggac tcttactgaa agcagaaagt ggacagaacc  24000
          ttaaaaattc atgaaatatc catttcagct tcagtaagga ttactgccca agaccgagtc  24060
          ttgtgctatc gtggaatagt cccacgctga actcccctct tctcttcccc aggcatcaat  24120
          gagctgaagg tgtttgtgga cctggcctcc atctcagcgg gggagaatga cattgatgtg  24180
          gaccgggtgg cctgcttcca tgacgctgtg cagggctacg catccctgct atttaagctg  24240
          gaccccagcg tggacttcag tgcattcatg aagcatctga aaaagctgtg gaaggctctg  24300
          gataaggacc agtacctgcc caggaaactg gtgagtctta ttctgtctct aatgcagatt  24360
          ttgttgaata gagcattgct tagcaacgtt agggcagtga ctgtggaaat ggtggcacac  24420
          ctgtgtggta ggtttgtaca cagccgtttt caatgatatt taaaaagctt ttcttcataa  24480
          atggaaattc accatcttgt tacctagaaa gcaggataca aaattacatg acacatagta  24540
          atctctaagg tgcaaaacac acgtggaaaa aagacagaag ggaaatatgc tgaaacgttg  24600
          ccaggagttt tctctgaatg gttgtaattg tcattttatt ctgttacttt ttgttatttt  24660
          ctataattga tagaattttt tatcagaaaa aagtaaacat ttaaaattag ccaggcatgg  24720
          tggtgtgcgc ctgtaatccc agctactctg gaggctgaga cagaattgct tgaacccggg  24780
          aggcagagat agcagtgaac tgagatcaca ccactgtact ccagcctgag tgacaaagtg  24840
          agactctgtc tcaaaaaaaa gaaaagaaaa gaaaaaagta aacatttaag tttaagtaaa  24900
          ctacctgtag cagggtctga attgacgtac gcagcttaac tagatacctg ggccagcctc  24960
          cggacggctg ctctgcatgt gggtggagga agaagtgaca tatggaaggg caggtaaagc  25020
          tatcttcatt tttctgctag aaagtcagca gagtttccaa acaaaaccct ctgttgtgat  25080
          ttttcctaaa cttctcttat tgtacttggg gaccacagaa ggacactgag gacttgggac  25140
          tccacagcca ttgcttccag cgtcaccccc agagggttct ctgcattggg gacctggcag  25200
          aatgatggcg tctggtagag aggcaggcgg gcggctgctc attcccctcc actcctccac  25260
          agatgtaagt caagtgcccc catgtgccag ccggggcacc aggcactgga ggaaacgtgg  25320
          aacagcgagt acaaagcagc actgagtgac agatcatgtt gtcagggtgg cacctggtcc  25380
          agctggggcg ctgggtgggc gactgcgtcc tgagccctgg ggaagcgtgg ggagaaggct  25440
          ctgcagcgag gcagaggcgg gaggccgacc acaggaggga gaagggcaag atcctcgctc  25500
          caaccgtggc ccgtgttctc tccttttgtc cccatagtgt gactccgcca ggaacttgga  25560
          atggctgaag actgtgaatg agagtcatgg gtctgtggaa cgctcatccc tgaccctggc  25620
          cacggccatc aaccaaagag gcatctatgt gatccaggcg cccaaaggtg gccaaaaggt  25680
          gagcggtccc cagccctcgg cgcagctgcg gcccttctgc aggctgctgc cagtccaggt  25740
          cttctggccc caagaaagtg acttctaacc tatgctcttc acagatttcc ccagacacgg  25800
          ttctgcactt gatccttcct gagagccctg gcagccacga ggagtcacga gagtactctt  25860
          tagaggaggt gaaggagctt ttgaacaagt tgatgctgat gtctggcaag aaggatcgta  25920
          acaacacgga agtggagagg ttttcagagg tgagggcgca tctttgcagt ggcgctaagc  25980
          tggtggtgtc atctcgtccg tgagggctgt gtactcccaa gaaaacggaa aggatttgac  26040
          ttgggatttg actgataaga agggctctgc tcttaggccc atggagagta gagttggcac  26100
          atttgtaggg tgcatggaac tctagtccgc ggccccagag aggtcttaag gcaggcaggc  26160
          ccctgggtta gcagtccctc cttacgatcc gtaggatgaa cgctgaagct ggcagcctgt  26220
          ccaccgcact gagaaggagg ttggtcaccc agcaaatagc ccttagaaag acacttgaat  26280
          tgcctctctc actctgtaaa tcagcaagaa tccaaataac taagatttag atggacaaaa  26340
          cagaagtaat catattgaga atggtgtacc ggtctaagta atagtctctc aattttatta  26400
          taggttcttt ctctaaagtt gatttgtact ttacaaatgg tatcctttat ctctgctggg  26460
          tgcagtggct cacacctgta aagccagcac tttgggagcc caaggtggaa ggctcatttt  26520
          agcccaggag ttcatgacca gcctgggcaa catagcgaga ccctgtctca aaaagtataa  26580
          ggtttttttt tttcccaatt aaaaaaaaaa gataatttaa aaaaattaaa acagtccagg  26640
          catcatggtt cacactttgg gaggccgagg cgggcctatc acttgaggtc aggtgtttga  26700
          gaccagcctg gcgatatggt gaaaccccat ctctactaaa attacaaaaa ttagccgggc  26760
          atggtggcac gtgcctgtaa tcccagctgc tccggagact gaggcaggag aattgcttga  26820
          acccaggagg cagaggttgc agtgagccga gatcacacca ctgcactcca gcctgggcaa  26880
          caatgcaaga ctccatctca aaaaaaaatt aaaaaaaaaa aaaaattaaa acaaatgata  26940
          ccatttatct ctacaatgac tctttccctg atgagagtgc catcttctca ggtgggttgt  27000
          gtagatgagg agggaggcct tgtgagcgca gatcatgcag tgggcctgtg gacagggccg  27060
          tcttttggcg gtaggcctgt gtgctgttgc agagtagcgt gttaccctct cgcatggctc  27120
          tgtgagccaa cctcatggtt ctgcctctcc aggtcttctg cagtgtgcag aggctcagcc  27180
          aggccttcat cgacctgcac tctgctggga atatgctgtt caggacgtgg atcgccatgg  27240
          cctactgctc ccccaagcag ggtgtgtccc tccaaatgga ctttggcttg gacctggtga  27300
          cggagcttaa agaaggtgga gatgtcactg agctgctggc agccctctgc aggcagatgg  27360
          agcacttcct tgacagctgg aagagatttg tgacccagaa gcgaatggag cacttttacc  27420
          tgaacttcta cacggcagag cagctggttt acctgagcac tgagctcagg aagcagcccc  27480
          cgagtgatgc cgccctaacg atgctatcct tcatcaaaag caactgcacc ctgagggatg  27540
          tcttaagggc ctctgtgggg tgtgggagtg aggccgccag gtaccgcatg aggagagtca  27600
          tggaagagct cccgctgatg ctcttatcag agttcagcct ggtggacaag ctgaggatca  27660
          tcatggagca gtccatgagg tgccttcctg ccttcctgcc cgactgcctc gacctagaga  27720
          cccttggcca ctgtctggct cacctggcag ggatgggtgg gtctcccgtg gagcgttgtc  27780
          tcccgagagg tctgcaggtc ggccagccca acctcgtcgt ctgtggccac tccgaggtgt  27840
          tgccagccgc cctggctgtc tacatgcaaa ccccaagcca gcccctgccc acttacgatg  27900
          aggtgctgct ctgcaccccg gcaaccacct ttgaggaggt ggcactgttg ctgcgccgct  27960
          gcctgaccct gggctccctg gggcacaagg tctacagcct gctgttcgca gatcagctga  28020
          gctacgaggt ggcacgccaa gcggaggagc ttttccacaa tctgtgcacg cagcagcacc  28080
          gagaagacta ccagctcgtc atggtctgtg atggggactg ggagcactgc tacctcccct  28140
          ctgccttcag ccagcacaag gtcttcgtca ccccccaggc acccctcgag gccatccaag  28200
          cctacctggc aggtcactac cgggtcccga agcagaccct gtcggcggca gccgtgttca  28260
          atgaccggct gtgtgttggg atcgtggcct cggagcgagc aggtgttggt aaggagagcg  28320
          gcagggtggg caggccccgt ctcccaggga ctgcccgggg cccttccccc ctccagcaga  28380
          tgaagcctgt ctgcaggtgg agaaaccgag gctcagggag ggtgtgattc atctgtgggt  28440
          gtcaatcagg gtctgtgcca gaaccaggca ccctggtcac ctggtctccc acaatgggta  28500
          ttccctggga gccccattcc cttcctcctc tcagcaaaca tctctgcagt gtactttgtg  28560
          gttttttttt tttttttttt tttttttttt gagacagagt cttgctctgt cacccaggct  28620
          ggagtacagt ggcgtgatct tagctcactg caacctccgt tttctgggtt caagcaatta  28680
          tcctgcctca gcctcctgag tagctgggat tacaggtacc caccgccatc cctggctaat  28740
          ttattttttt ttgttttttg ttttttgttt ttttgagaca gagtctcact ctgttgccca  28800
          gattggagta cagtggcgtg atctcggctc actgcaacct tcgcctcccg gattcaagcg  28860
          attttcctgc ctcagcctcc caagtagcta ggactacagg catgcaccag tacacccagc  28920
          taattttttt atttttagta gagatgtggc ttcaccgtgt tagccaggat ggtctcgatc  28980
          tcctgacctc atgatctgcc ctcctcggcc tcccaaagta ctgggatcac aggcatgagc  29040
          caccgtgccc ggcctaattt ttgtattttt agcagagaca gggtttcacc atgttggcca  29100
          gtctggtctc aaactcctga cctcaggtga tccgcccacc tcagcctccc aaagtgctgg  29160
          gattacaggt gtgagccacc acgcccggcc tgaagtttac ttcttctgcc cttaaatgcc  29220
          actggcctct ttggggttga tgttggtcgt gtgagcaagg ggaggtagaa ttgaagagaa  29280
          agccatgcct cttgacccac ccttcgtttg ccatcttgtt tcccttaaaa agaaatagta  29340
          gcttctgttc tgttgacttt atcctatcaa cagtacctcg tcctgttggg ataaacatta  29400
          ctcttcccct ccctgctgaa gcctctcctt ttgctgtgac ttttattagc tagtcactca  29460
          acacataatg acatttcagt caacagcaga ccacgtatat gaccacggtc ccataagatt  29520
          agaaaactgt actttaaaaa ttagccaggc atggtggtgc atgcctgtga tcccagctac  29580
          taggaaggct gacttgggag gatcgctcca gcccaagagg tcgaggctgt ggtgagctgc  29640
          aaatacgaca ctgcactcca gcctaggcaa cggggcaagg ccttggtctt ttaaaaaaag  29700
          agaaagaaag aaagaacaaa agattataat accatatttt ttactgtacc ttttctacat  29760
          ttttattttt atttttgaga tggagtctca ctctgttgcc caggctggag tgcaatggca  29820
          cgatctcggc tcactgcagc ctctgcctcc tgggttcaag cgattctcct gcctcagcct  29880
          cctgagtagc tgggactaca ggcacacgcc accacacctg actagttttt agtagagatg  29940
          gggtttcacc atgttggcca ggctggtctc aaactcctga ccttgagtga tcacccgcct  30000
          cagcctccca aagtgctggg attacaggcc tgagccaccg tgcctggcct gaatatgttt  30060
          agatattcag atatttgccc cgtgtcacag ctccccactg tatgtaggat gcccccatgc  30120
          tgtcacggct tgcagcccag gggcaatggg ctattccacc tagctcgggt gtgtggtcgg  30180
          ctctaccatc tgggtttctg caggcacact ctgatgttca cagtgacaga atcatttcac  30240
          aatgcatttt tcagaacgtg tccctagtgc taagtggcgc gggactctgc tttgcctgct  30300
          gtcctgcgga ggcaggaggt gaccaggaga gtgagtaggt aacggctggg aaatgtgaag  30360
          gttcaagagc gtattcttga atctgatgtt atgttgcatc agttttgaat tttatacaaa  30420
          gagaagtaac ttctagtgga tctttataga ttctcttact ctttgtccta gccctgggac  30480
          ttaatttttc tctctctctc tctctctatt tttatatata tacacacaca tgctgtatat  30540
          acatacacta tatatattcg atacatattc tatatagatt tctatatata ttctatatat  30600
          ttttacatat ataatatata ttctatatac ttccatatat actatatata ttctatatat  30660
          acatatatag tatgtatata tatattatat atatattgta tgtatatata tattatatat  30720
          atatattttt tgagacagag tttcgctctg tcaccctaac gatgacaact gcaccctaag  30780
          ggatgtctta agggatgccc aggctggagt gtagtggtgc aatctcagct cactacaacc  30840
          tccgcctccc gggttcaagc gattctcctg cctcagcctc ctgagtagct gggattacag  30900
          gtgcctgcca ccacgcctgg ctaatttttt tgtattttta gtagggacgg gatttcacca  30960
          cgttgaccag gctggctttg aactcctgac ctcaagtgat ccccccgcct cggcctccca  31020
          aagtgctagg attacaggtg tgagccacca ctcccagccc taatttctgt attaatgtta  31080
          taggaaagtc tctgtacgtg aagaggttgc acgacaaaat gaagatgcag ttaaacgtga  31140
          aaaatgtgcc tctgaaaaca attcgactga tcgaccctca ggtggatgag agccgagtcc  31200
          tgggcgccct gctgcccttc ctggatgcgc agtatcagaa ggtccccgtg ctctttcacc  31260
          tggacgtgac ctcctcagta agtgccctcc agcgtcagcc gatggccaca tcagtaaaga  31320
          cgtggtcccc atgtctctgc gtgactcctc cccgtgtata gaattccttg tttccacacg  31380
          cacagtcctg tgaagcttaa cagtgggaat gtgctctgag aagtgtgttg tcaggcagtt  31440
          tcctccttgt gtgaacgtca tggtgtgcgc ttacactaac ctagacgtag agcccactgc  31500
          acacacaggc tttatggtac acactgtcgc tcctaggccg caaacctgtg ctgcatatgg  31560
          ctgttctgaa tcctggagcc aattgtaaaa cggtgtattt atgtgtctaa acataaaaat  31620
          ggtacaggga aatatagtat taggatttta tggggctgcc cttggagaca tgggccgttg  31680
          ttggctgaaa tgttgatgtt gatcatcagg atcatcgtga caaagagcaa aataaggagg  31740
          ggttacttag agttgggaga actcgccatc gtgtcgtgtg tttacacctc gtgcgattct  31800
          gttcttaggt gcagactgga atttgggtgt ttcttttcaa gctcctcatt ttacaatact  31860
          taatggatat aaatgggaaa atgtggcttc ggaacccctg ccatttgtat atcgttgaaa  31920
          tcctggaaag gaggacgtca gtgccgtcga ggagctcttc agcgctggtc tgtactgtgg  31980
          ggcgttttcg cctggcgtgg ggggctcttg ggttctttct ggtcttactg aagtggaatg  32040
          gcgcgtttag gagactccac atctttgcct tacttagtgc agcagctgaa tgcagtgtta  32100
          gtaaagaaaa gcccatcttt aaactcactt tttaatcatg tctgggataa aagtactctt  32160
          ctgttaatta gcagtgtctt caatatttct gttcaattca ggcttcatgc tgtatgccca  32220
          gtctgaatcc cagctgtgct ctgaatctag gaaattcatc tgttgaaaga cctcaccttt  32280
          cctaatgcca gctaagatga gaaggagatg tttgtcaaaa atttcttagc aaaagagagt  32340
          tttatgttca ctcacataca taatacatgt atagcttagt ggagaaactt agtttcagga  32400
          agttgggtta gaaagtgatt tcctggctca gaacgcagct cccacagcaa tgccttactt  32460
          aatgtgcaaa agatatgctg tggaaaaaaa gactatacag aaagctacat attttcagtg  32520
          cgtttttcat aaaggtccat ccaatataga taacgtggag ggttaagaca caaaagcatt  32580
          tcttagaaag tcttcttgta accatttcat taatgtctct cctttccagc gtacacgtgt  32640
          accccagttc agttttcttg acatcttccc aaaagtcacc tgcaggcctc ccaaagaggt  32700
          gatagacatg gagctgagtg ccctgaggag tgacacagag cctgggatgg atctgtggga  32760
          gttctgcagc gaaactttcc aaagacctta ccagtattta agacgattca atcaaaacca  32820
          agacctagac acgtttcagt atcaagaagg ctctgtcgaa ggcaccccgg aggaatgcct  32880
          ccagcatttc ctgtttcact gcggggtaat aaacccatcc tggtcagagc ttcggaactt  32940
          tgctcggttc ctgaattatc agctcagaga ttgtgaggcc tctctcttct gcaatccgag  33000
          ttttattggc gacacactga ggggcttcaa gaagttcgtg gtgaccttca tgatctttat  33060
          ggcaagagat tttgccacac catcactcca cacctctgac caaagcccgg ggaagcacat  33120
          ggtcaccatg gatggggtta gggaagaaga tctagcgccc ttctccctcc ggaagaggtg  33180
          ggagtcggag cctcacccat acgttttctt caatgacgac cacacaacca tgacattcat  33240
          cggcttccat ctgcagccca acatcaacgg cagtgtcgat gccatcagtc acttgactgg  33300
          gaaggtcatc aagagagacg tcatgaccag ggacctgtac cagggcctgc tgctccagag  33360
          ggtgcccttc aatgtcgact ttgataaact gcccagacac aagaaacttg agaggctctg  33420
          cctgacctta gggatccccc aggccaccga ccccgacaaa acgtatgagc tcacaaccga  33480
          caatatgctt aaaatccttg ccatcgagat gcggttccgg tgtgggatcc cggttatcat  33540
          catgggagaa actggctgtg ggaaaaccag gcttattaaa ttccttagcg acctgcggcg  33600
          tggtggtacc aatgctgaca ccataaagct ggtcaaggtg cacggaggaa caactgcaga  33660
          catgatctac tccagagtca gggaggctga aaatgtggcc ttcgccaata aggaccaaca  33720
          tcagttggac accatcttgt tttttgatga agccaacaca acggaagcta taagctgtat  33780
          caaagaagtc ctgtgtgatc atatggtgga tggccagcct ctggctgagg actctggcct  33840
          gcatattata gctgcctgca atccataccg gaagcactct gaggagatga tctgccgttt  33900
          ggagtcagct ggtttgggct acagggttag tatggaggag acggccgaca ggctgggctc  33960
          cattcctctg aggcagctgg tataccgggt ccatgctctg cccccgagcc tgattcctct  34020
          ggtgtgggac tttggacaac tgagtgacgt tgctgaaaag ctctacatcc agcagattgt  34080
          ccagagactg gttgagtcca tcagcctaga tgaaaacggg actcgcgtga tcacagaagt  34140
          cctctgcgcc tctcagggtt tcatgaggaa aacagaagat gagtgcagct ttgtcagcct  34200
          cagggacgtg gagcgctgtg tgaaagtttt caggtggttc cacgagcaca gcgcgatgct  34260
          cttagcgcag ctgaatgcct ttctctccaa gtccagcgtc agcaaaaatc acaccgagag  34320
          agatcccgtc ctctggtcgt tgatgctggc catcggggtg tgttaccatg cctctttaga  34380
          aaagaaagac tcatatcgga aagccatcgc caggttcttt ccgaaaccgt atgacgacag  34440
          caggctgctt ctggatgaaa taacacgggc acaggatctt tttctggacg gcgtacctct  34500
          gaggaaaacc atcgccaaga acttggcctt gaaggagaac gtcttcatga tggtcgtctg  34560
          catcgagctg aagattcccc tcttcctggt ggggaagccc ggcagctcca agtctctcgc  34620
          caagaccatc gtggcagacg ccatgcaggg cccggctgcc tactcagatc tcttccgcag  34680
          cctgaagcag gtccacctgg tgtccttcca gtgcagcccg cactccaccc cacagggcat  34740
          catcagcacc ttccggcagt gcgcccgctt tcagcagggg aaggacctgc agcagtacgt  34800
          ctctgtggtg gtgttagatg aggtggggct ggcggaagac tcacccaaaa tgcccctgaa  34860
          gactctgcac ccgctgctgg aagacggatg cattgaagac gatcccgccc cccacaaaaa  34920
          ggtcggcttc gtgggcatct ccaactgggc ccttgaccct gccaagatga accggggcat  34980
          ttttgtgtca cgtggcagcc ccaacgagac agagctcata gagagcgcca agggcatctg  35040
          ctcctcagac atcctcgtcc aggaccgagt ccaagggtac tttgcgtcct ttgccaaagc  35100
          ctacgaaacg gtgtgtaagc gccaggacaa ggaattcttc gggcttcgtg actactacag  35160
          cctcatcaaa atggtctttg ctgcagcaaa ggcttcaaat agaaagcctt ccccgcaaga  35220
          cattgcacag gctgtcctta ggaacttcag tggcaaggat gacatccaag ctttggacat  35280
          ctttctggcc aatttgcccg aggccaagtg ctcagaggaa gtcagcccca tgcagctgat  35340
          caaacagaac atctttgggc cttctcagaa ggtgccgggt ggagagcagg aagatgctga  35400
          gtcccgctac ttactcgtgc tgaccaaaaa ctacgtggca ctgcagatcc tgcagcagac  35460
          attcttcgag ggggaccagc agccggagat tatttttggt tctggtttcc ccaaggacca  35520
          agagtacacc cagctctgca gaaacatcaa tcgtgtgaag atctgcatgg aaacaggcaa  35580
          gatggtgttg cttctcaacc tgcagaacct ctacgagagc ctctacgacg cactcaacca  35640
          gtactacgtc cacctcggcg gccagaagta cgtggacctc ggtctgggga cccaccgcgt  35700
          caaatgtcgg gttcacccca acttccgcct gattgtcatt gaagagaaag acgtcgtgta  35760
          caaacacttt cccatccccc tcattaaccg gctggagaag cactatctgg atatcaacac  35820
          ggtgctggag aaatggcaga agagcatcgt ggaggagctc tgtgcgtggg tggagaagtt  35880
          catcaatgtc aaagcacatc atttccagaa gaggcacaaa tacagcccct ctgacgtctt  35940
          catcggctac cactcggacg cctgcgcgtc tgtggtgctg caggtcatag agaggcaggg  36000
          tccccgggcc ttgacggagg aacttcacca gaaggtgtct gaggaggcca aatcgatcct  36060
          gctgaactgc gctacgcccg atgccgtggt ccggctgagc gcctactcgc tgggcgggtt  36120
          cgcagcggag tggctgtcgc aggagtactt tcacagacag aggcacaact cctttgcaga  36180
          tttccttcag gcacacctgc acacggcaga cctggagcgc cacgccatct tcacagaggt  36240
          gattgtcttt ctgcacttgt accctatccc ctgtcaccca agagtcctaa atccctcgtg  36300
          tcaggattca agattcttcc ccaggcagcg gttagggatc ctgcagggag atgctgagac  36360
          gctgagctct cctccgcggt aagtgtgggg agtaggtcca gttaaccagg tgctgagtgc  36420
          ctggctctgt gcagtgcacc atgctggtaa cagcaccata cacagtgttc acaccaacaa  36480
          ataaagtacc acgtcccagg actgggccaa gggcactagg gacgcacaga tgaatctgta  36540
          gcccttgtcc tttgttagca ttagggagca tggagagacc agcacatgaa cagatgccat  36600
          caatatcata tgataaatgc tgtgcttaga ggcagcgggg agcggtgcag accaggatgc  36660
          gagctcagat gagatgttcc ctaggagaag cccctcgccg atggggaaga atggccggga  36720
          agggattgta ggctgagggc cttctgtggg cagagccgct gacagctctt agggttcaag  36780
          gctgtagtgc tgagatgggg cgatgaggtg cagtcagaga gaactactgg aggccctcag  36840
          tgactctgca gagccacatc tcagccctat ggagcgggca ctggaggcac gcttgtctcc  36900
          ctggctgggt gaagggagtc tgatgaaagg ctgttgtgga aaagacgggc cggtagggag  36960
          gccgctggaa ccgtacaaag gagaggagca gatggaaccg agagatactc aggaggcaat  37020
          ttggcagggc caataccacc acccagtggg gggatggggg gtggaggggt ccggggcgac  37080
          cccctggatt cctccttaga tgagtggaca ttgcttcatc atgacagata ccgcaggaac  37140
          ggacagcagg ttgtgggagg ctagtgatga tgtccgccgg ggacaggttt ctatgcatcg  37200
          tgcagctgga cgtaggaatc tgagctcagt ggtgaggcag ggattcctgg gctagagcag  37260
          caggcctcga ggaacgtttc gacttgcact gtgatggggg agtgaccttt gggacaggag  37320
          aattgctgac atctggggga aggggacagc accaaccacg aactccatct gaaagcatga  37380
          gtcgtactat aacaggaaat ggcatttgtg ctgagcccta agggatcatg agaatctcaa  37440
          gtacggacca agcaggcaga gacacgggcc tctggggagg agaggaaggc accctcgggg  37500
          cagggtgggg tcgtctctcc aatgcctttg gccctgtagg gcctctcggc cccagcgctg  37560
          ccgtgttttg ggaaactcct ttgggtttgg attctgtgcc gttgtgtggc aactgcaccg  37620
          cgctgaacat cgcaggtttc taggatctgt ctaaacctgg cagcagactt gcaacctttc  37680
          cttgaagtct ggcaagtaat ttgcatttct taactctgta gatcaccact ttctccaggc  37740
          tgctaacaag tcacgactgt gaaattttag aatcagaggt cacaggcagg gctccgaaac  37800
          ccacactcct gtggctgcag cagtttgaca ccgagtactc attcctcaaa gaagtccggt  37860
          gaggttccct gccttccctg ctgccctctc cctccccagc cgcagccgtg tggcttctgc  37920
          gtggcgatgg tacccgcgcc ggttaatgag cgccacagtc acgtgactgt gaaatagatc  37980
          cttgttaaat ctctcccagc atccctctca tctccatcat cttctgcaac gcggtgtctg  38040
          gcctaacatc ctcctccgag agcaccatcc tcggacctcg ttaggaggca ttccttgggt  38100
          ttcctcccct ggactatctg ttcttactga agaaaatcct acctgagtag ctgtttcttt  38160
          gtagccttta tgtttcccat cactttgggg aattttcttt tccatttttt taagacagag  38220
          aactcacttg aataacttcc cttttctttc agaaactgtt taacgaatac agccaaatgt  38280
          aaaatcctca tttttcagac agattttgaa gatggaatcc gtagcgccca gctcattgcc  38340
          tcagctaagt atgtttttag tatttttctc agaaactatg taaaaaaccc aaaacgtagg  38400
          aagtcctaga gaattttttc cttgaagaca gtatagtatc ataatcagta tagaaataaa  38460
          aataacaatt cttcccccgc ctcattcccc caagtgggat tagggaaact gaagagagac  38520
          aaaaagaaaa ggccaataac attacaaaaa tagtggaatg ggcctgggca acagagcaag  38580
          acctcatttc taaaaaaata aaataattag ccttccacag tgcacctcta gtcccagctg  38640
          ctcagaaggc tgaggtggga ggatcgcttg agcctgggag gtcaaggctg cagtgaactg  38700
          cgatcccacc actgcagtcc agcctagggg ccagagcaag agcctgtcct ccccacaaaa  38760
          aaggtgaaat gcgagaggtg taaataatgg aacattaaca agctataaaa ggatgccttt  38820
          gaagcctgtg tttgtagaca tgttttggtc attattaatt ttgaattata caatttgaat  38880
          ttatttcaag ttcgagggaa acaacagtag gtaaatgctt tttttcctat ttattggata  38940
          tttttatagt gtttgtaggg gaagtctgat gctcttagaa ttaactttgt gcctttatta  39000
          cttaaagtaa aagtgatttc tggacctttt tgaagcattg gatgccatat ttcagttcgt  39060
          ggcttaaatc tcaacaagaa actggctttg gccattggtc atctgaaggg aatggcattg  39120
          cgcacagaac tctttgttga aatggaaagg tccactgggt acaggggctg tttcctgtaa  39180
          tcctagctac ttgggaagca gaggcaggag gatcgtttga ggccaggagt ttgagaccag  39240
          gctgggcaac acagcaagac ccccatcgct taagagaaaa gaaggaatgg aaagttcagc  39300
          tgtcctcacc cttagctgca ccggggcagg cccattgagg agcacaagat agggtttctg  39360
          gtcaacgaag gaatgccact tcaaagcaga ggacacagga atggggaaga aaacgagccg  39420
          ctaagagaag atttctcatc cccttgtgag agaagaaatc acgatcgcag ggctctgaag  39480
          tttatgtaaa actcatcgga acgggtggcc gtgagaccga accaacagct cggagaacac  39540
          ccttctgcag ctgcacagct ttgctttgtt tatttgcttg tttttgtgtg tgtgtttgtt  39600
          tttaaaatag gtattctttt ttttttcttt aaataggtat tctgttataa atgaaatcaa  39660
          caaaatacga gaaaatgagg accgtatctt cgtctatttc atcacaaaac tgtcccgggt  39720
          gggaagagga acagcctatg tgggcttcca cggaggtgag atcagaacat cagtcagggt  39780
          atttatttat gtatttattt atttatttgt atctatttat tttttgagat ggagtcttgc  39840
          tctgtcacca ggctggagtg cagtggcgcg atctcagctc actacaacct caatctcctg  39900
          ggttcaagcg attctcctgc ctcagcctcc caagtagctg gcattacagg cgtgcgccac  39960
          catgcccagc taatttttgt atgtttagta gtgacggggt ttcaccacgt tggcctagat  40020
          ggtctcaatc cgttgacctc atgatccgct cgccccagcc tcccaaagtg ctgggattac  40080
          aggtgtgagc caccgcaccc agcccagtca gtgtatttat ttaagtcatg ttggaactgt  40140
          ttctcatttg gttctgtgtt gtacagtctg aaattagaat attattgtta acctcaagag  40200
          gattctttcc agatgcaatt agatttctta ccactgatta ccatgaaaac atgaatcctg  40260
          ggatgggagg ctgcgtgcac ctctcctgga ctgactctag gcaagctcct cacctcttag  40320
          catgtaggtc acacggcgtg gagactcccg actcccgaca gacactgtca ggaacgcacc  40380
          gatacgcctg tttggcgggg agggagagtg gcgggggtcg gactatcttc agatctcttt  40440
          ttttccaagg aatggtcacc agctatttat gacatagaaa agttggtatt ccagaaacag  40500
          gaaagtaagt ttacttgaat aatttcgtgg agaatggaag gcagaccttg ccagtgtccc  40560
          ccacccctca ctaactgtga tacagcaaat acaacaatgc atgggtgaaa gaaccacagg  40620
          ccttatccat gcgtccttcc cacgctggcc attgcaggtc ttaccgttgc tgcttatggt  40680
          gaagctgtcg atgggcatag aatcgggtcg tgtatagtat cgggttgggt ggtttctgcg  40740
          caggcccatt ccagggtttc ggcttcaggg tgccagtcat tcattgcgca gcaagataat  40800
          gacaagccag ggtgtgcaat gtccctgctt agggctgagc agcagccggg aaagacacaa  40860
          agacagttgt gggtggcttc actcttcaca gggctgtggc agtctgtcca catcgatgac  40920
          ctccggagat ccaccctcat ggtttctgat gtgaccaggc tgcagcatgt caccatcagc  40980
          cagctgttcg cgcccggaga cttgcctgag cgtgagtcac gaggcggagc ccctggggga  41040
          gcaggtggtg gaagggcaga tggcaggtgt ggagcgtggc gtgcacatgg cactaggagc  41100
          agggccaccg tgtttcgtcc ctcggcagga gctcggggac acatctgcag aactgactgg  41160
          tggctcatca tagagcacca gggccgagca ggtgcgctta ccacaggctg aggtagagct  41220
          ctgtgagcag gccagccatg gaagtgagca cctagaacac gccagagccc aggctggaag  41280
          gaaggggctg ccttgggggc tgatcttcat gaccgtgatc tctcatctgg ggacctagca  41340
          ccacagcagg ggccggggaa gcctgcactc ggaggctgag cacacagact cccagatggc  41400
          accgctgcca gtccctgtgc caccttctga gtggtaacgc aatcacgttt gcttcgactg  41460
          cagtgggctt ggaacaccgg gcggaagacg gccatgagga ggcgatggag acggaggcca  41520
          gcacatcagg ggaggtggca gaggtggcag aggaggccat ggaaacagaa agttctgaga  41580
          aggtgggaaa ggaaacctct gaactcggag gcagtgatgt aagttctggt tcttgggacc  41640
          tccccttgtg ctgctggtga tgcttctgag ctgcatcttt aaacgctttt gcattgggag  41700
          ctagaggagt cgccgccgct gtgcaggggt gaggatggcg ccccactttc ctcacacagt  41760
          gacggtcttg ttgctggtta ctgggggtca agggcatctg caccggcagt ttggggggtg  41820
          cagggcggag gtcggcgtct cttctttgtc cgtgaggacc gccgccctgt gctgtttgct  41880
          gcattgagac cctcatcgca tacgggcggt ttggcttttg cccactgtgt cagtggcaga  41940
          aacggatgac ccaaccgtct ccaccaacag gtgtcgatcc tggacaccac caggctgctg  42000
          agaagctgtg tgcagagcgc cgtgggcatg ctcagagacc agaacgagag ctgcacgcgc  42060
          aatatgcgga gggtggtgct cctcctgggc ctcttgaatg aggatgacgc gtgccacggt  42120
          atgagcctcc ccacccctct tgcccctgcc cccacgtggg ctcttcctga ggagtgggca  42180
          tcatttcact gtgtgttggg ggacaccctc tcaggtttcc atggctcagc agaagcagtg  42240
          acacagtggg aatctaagag catctctcag attttgctct agaattggcc tggccaacgg  42300
          acttcccttc ctgggggagg tgggacagaa gcactccgga gccaacagct cagccacggc  42360
          catgctgaac gtctgtttct gcctttgtac agcctctttc ttgcgggtat ccaagatgcg  42420
          cctcagtgtc tttttaaaga agcaagaaga gagccagttt caccctctgg agtggttggc  42480
          aagggaagcc tgcaaccagg acgctctcca ggaggcgggc acattcaggt actgtgacta  42540
          aaggaagcaa ggagtggctc caatctggtg gcagcatggg gacctgcctg cagggatcct  42600
          ctctccatcc gggccatggg gactgagctg tttctttcca aacctctcag ccattcaaag  42660
          ctgtaaagtt tttccccaag aagcacacag taggtctgga cagtggccaa atggcaggtg  42720
          ctggactctt cctctaattt cgtgtttaca gtttttcata ctaaaaactt aaaaaaagta  42780
          aaacatctgt tcttagagta gaacatttac cgacattcat gttgataacc ctagaaaggg  42840
          ctgctgtttt cagtcatgaa gttaaaatga cgtgcagagc aggcagggga caggcgggat  42900
          tttcccagtc ctgctgtttg aagaatggta acagcaaaac caggacccag cagtatattc  42960
          actgccatgg ttatttttct gtcacccatg agactaacct tgattatctt ggatgtggcc  43020
          gtgtattgag gaaggagggg tgctctgggc cccagacaga gggtctcttt aagacagact  43080
          ctcagacctc ctgcctgaaa gcctaagaaa ccagtgactt ggttatttgg gcccagtttt  43140
          cccatctcta aaagacagcg gactcctcca tgagtcccct tccaggtcca agcttctgtg  43200
          ccagtgatag gttcgctttg ggcctacagc caggtgtgat ctgcaggagg gaacgtgagg  43260
          aagaagcggg gtgaacggta atgggggctt acaggggaag aagcggggtg aacgggaatg  43320
          ggagcttaca ggggaagaag cggggtgaat gggaatgggg gctcacggag gaagaagcgg  43380
          ggtggatggg aatcggggct cacggaggaa gaggggtgac cgggaatggg ggctcacaga  43440
          ggaagaagcg gggtgaccgg gaatgggggc ttacaggggg aagaagcggg gtggacggga  43500
          atgggggctt atggaggaag aagcggggtg agtgggaatg ggggcttaca ggggaagaag  43560
          cggggtgagt gggaatgggg gcttacaggg gaagaagcgg ggtggacggg aatgggggct  43620
          tacaggggga agaagcgggg tgaccgggaa tgggggctta cagaggaaga agcggggtgg  43680
          acgggaatgg gggctcacgg aggaagaagc ggggtgaatg ggaatggggg ctcatggagg  43740
          aaaaagcggg gtgaccggga atgggggctt acaggagaag aagcggggtg aacgggaatg  43800
          gggacttaca gacaccttcc tcgtgaccag agattttctg attctacttt ttctctagtt  43860
          atccttcgtt tctctccttg tcacgccttc tgaagggatt ttaggagatc agaaatattt  43920
          tcatttccct ccgttcctcc ttgtggactc tcttgatgct tttttttttt tgagacggag  43980
          tctcactctg tcgcccaggc tggagtgcag tgatgcgatc tcagctcact gaaacttcca  44040
          cctcctgggt tcaagcgatt ctcctgcctc agactcctga gtagctgaga ctataggcac  44100
          ccaccaccac acccagctac ttttggtatt tttagtagag gcgagatttc accatgttgg  44160
          ccaggctggt ctcaaactcc tgacctcagg tgatccactc gcctcagcct cccgaagtgc  44220
          tgggattcca ggcgtgagcc agtgtgcccg gcctgttgat gcttttgaat ccctgactcc  44280
          actccccggg accagccctg agtcactgaa cctcctcagt ctgctcttcc ccactctgct  44340
          gttcacgcag cactaggcct ggctccgtcg tgttctgtgg tcaccgtgag gcctgcgcag  44400
          ccgctgagtg gtggccagac ccgcaccctc agctcacctg ccccagggcc agcagcaccc  44460
          tgactacctc gattcaccac cactgtgttc tggggactgg agtcctttgc cctctcggga  44520
          ttaaacagcc caaatcctga gagtcctttg tgtcccgaac tctgcctgcc tgtccagata  44580
          cagcagaacc aggctcagcg gctccagata gggcggaacc aggctcggcg gctcccgcct  44640
          ctcccagcgc ttgtcccagc gcctgggttt tccttctgcc ttttgtgttc gcgacacttt  44700
          tcctagtttg ctgttttctc cctctgtgca ctgggatgct ttattttccc aatagacatt  44760
          ttaaaattct tgccaggttc ctctgtacta tatatttaaa aaatgtaggt atttcttttt  44820
          attctcttca aaagagaggc ttcgcttttc ccccaacatt aattaccttg tggggttttt  44880
          tttttttcga gacagagtct cactctcgtc ccccatgctg gagtgcaatg gcgcgatttt  44940
          ggctcactgc aacttctgcc tcccgggttc aagcgattct cctgctcagc ctcctgagta  45000
          gctgggatta caggtgcctg ccaccacgac tgtaattttt gtatttttag tagagacggg  45060
          atttcaccat gttggccagg ctggtctcga actcctgacc tcaggtgatc cgcccgcctc  45120
          agcctcccaa cgtgctggga ttagacgtga gccaccgtgc ccagccacct tttaattctt  45180
          atcctttaca caagaatttt gaaatagagc tattattgtt acatgtaaat atatacaaca  45240
          aaatatatat aacaacaaaa tgtcttgtag ttaaccaatt atctttctgt ctgcctatct  45300
          gtgcattcat ccatccctcc gcctgcctgt ccatccaccc atctgtccgt ccgcccatct  45360
          atccatccac ctgtctatca gacactcaga tctagtgtac aaaaacatca acaggaacaa  45420
          atacttagtt ccagataaac atgtgccttc ttgtttagtt tgatctggga caaattcatt  45480
          ttggtctctt catctgtatt atagtctatc tacaacagat ttttaaaata tttatttttt  45540
          ccaaatgaat cgtcataatt ttatttattt agagaacctc gatgacttgt tctgaaaaat  45600
          agttacatac aaaaattatg cagccttgca aaaaataaag cagataagtg cggtggctca  45660
          cacctgtaat cccaatactt tgggaggcca aggcgggagg attacttgtg cccaggagtt  45720
          tgagaccagc cagctagggc aacatagtga gaccccatct caacaaaaaa taaaataaaa  45780
          tttaaaaatt agctgggcat ggtggcactg ggtgtgttgt tcctgtctac ttgcacggct  45840
          gaggtgggag gatcgtttga gcccaggtat tccaggttat gacgatctat gattgtgtca  45900
          ctacaccgca gttggcgtga cagagtgaga ccctcacata catgttttaa aaataaaaaa  45960
          gcaaacacta cttcaccctt ccagtaacct aatgacagtt tattagatgt agaattaagt  46020
          tccattccag ttccgtctct aatcttagac atctttgtga gtctgttttc taggacttaa  46080
          aaatgatgga aatgtcaagt tattgctgtc gctgtagtgt ggtaaatagt agactagttg  46140
          ttttgttaat gctcaagaag gaacaaaatg tcaaaaggtg gcagaccgcc actctggttc  46200
          ctctgacccg tggtggccca tctctcttct gtgctgcagg cacaccctct ggaagcgggt  46260
          ccaaggtgct gtcacccctc tgctggcgag catgatatca ttcatcgaca gagacggcaa  46320
          cctagagtta ctgaccaggc cagatactcc gccctgggca agagatcttt ggatgtttat  46380
          tttcagtgac acgatgcttc tgaacattcc tcttgtgatg aataatgaaa ggtgagtgga  46440
          aggctttctt tccctgggga gagaaactat cagaacacag caggacccta atatgctctc  46500
          ccaagtgctg ggtgaaacgc agccctcaac ttcagagcaa cgttgacatg ggtgctttct  46560
          gcagtaacaa taggaagttt ggccgggcat ggtggctcac gcctgtaatc ccagcacttt  46620
          gggaggccga ggcaggtgga tcatgaggtc aagagatcaa gaccgtcctg gccaacgtgg  46680
          tgaaaccccg tctctactaa aaatacaaaa attagctggg cgtggtggcg cgtgcctgta  46740
          ttcccagcta tttgggaggc tgaggcagga gaattgcttg aacctgggag gcggaggttg  46800
          cagtgagccg agatggcgcc actgcactcc agcctggtga cagagcaaga ctctgtctca  46860
          aaaaaaaaga ataggaagtt tacgaagctc tgagaaattt ctgttttatc tccaccctcc  46920
          tcatttccct gctttcagag cactggttct agccagaccc agcatggcgt gacacggaga  46980
          cagtgcgctg cgaacagccc cacaatctgt gctccttacc cctgggatct gtgctccctc  47040
          cccgtccctc attccctggt ggagcggcac agcccccacc cccttccgca ggcctgatga  47100
          tgtgcggctc aggctcagct cccaatagct tccacttcag ctttcagggg cttcaattct  47160
          ggatgtagat ttataaagaa tatagaaata aatgtgccca ggctcggtgg ctcatgccta  47220
          taaccccagc aatttagtag gctgaggcag gaaagtttct tgaacccagg ggttgaagac  47280
          cagcttgggc aacatagtga gaccccatca ctacaaaaaa tttaaaaatt aggcataacg  47340
          tggtgcgcac ctgtagtccc agctactcta gaagctgagg cgggaggatt gcttgagccc  47400
          aggagtttga ggtgagatag gatcacacca ctcactgcac tctagcctgg gtggtgacag  47460
          agtgagactc tatctcaaaa aaaaaaaaaa aaaaaaaaaa aaaagagtga gagagggagg  47520
          gagacagaag gaagaaagag aaagaaagag cgagagaaag agagaaagaa agtaaagaaa  47580
          gaaagagtga gagaaagaaa gaaatggaat ttgaattgcc agtggaaaca cttatttaaa  47640
          agacaaggcg ctgctgatgt tcatgaagca aagactctaa caagttgtgc tctgtgttac  47700
          aagttatcaa agccagacag gttcaggaac cagaagactt ggttctgccc gagattttgg  47760
          gcaacacact tgacccctgt cagccttggt ttgtttttgt tttgcctgtg aaacaaagat  47820
          tgcataagac agttccctag ttctgtcata acagaaaccc tgtactgtga aacagatcag  47880
          cgccgtctgc ctggcctgtt ggcccctttg tttttgaggt ctgagaagag ctggcatcag  47940
          tggcagatct tatcttgtgt tttgagtgac gtctcacaaa ccctcttctt atcatccctc  48000
          accttattgc agacataaag gtgagatggc ctacatcgtg gtgcagaacc acatgaacct  48060
          ttccgagaac gcttccaaca acgtcccttt cagctggaaa atcaaggact atctggagga  48120
          gctgtgggtc caggctcagt acatcacaga cgcagaaggt gaggctacct caagacaggt  48180
          cagattcagc acaggtgaat cacaaaggga ttgcctgaca gtgaaaagca gatgggtggc  48240
          tagaattgca aggtgaattt tggagttttt agttttcaca ctttgtttgt gcagtaagcg  48300
          tccaatttac gtcaccgcgt cattttaaag tttctgctga aggagtgaga ggccccggcg  48360
          ggaccagaaa cctttcgatc ctatggcagc aggagcctgt gagatggttt ttagtgccgt  48420
          gatggccagg gatatggcga aatggggtgt gttctggcaa gaggaggact gtcgcctcta  48480
          tcagctggtc attcccattc tgggccttct cagactgggg cactggactc ggaagatgcc  48540
          cccaggagag gcgttctcag aaggcacgag cgcctggagc atcccctact cccaggtgcc  48600
          ccatcaggag gcacctccca gctgtgtctc ccgagtcaca gcccagacac agtgctgagc  48660
          tctgctgcca gatgccagaa gatttgccct agtccagaaa aaccaacgac aacgcaacac  48720
          ttttacaaaa gccatctttc atacatgcaa tagtcttttc cacgtttact tatcgtacca  48780
          tttggaagac tcagggtggc cttcttttct aggttaccat tctgccactt tttctcaaag  48840
          cagtctctct cctcatgagc atattccttt ctcaggacaa taccccaact gaccctgctt  48900
          ttctatgaca gcatgcgaat taggggctgc accccgccca ctagaagcca gatctttctg  48960
          gcttgcatgc tctgtgaccc ccagcccctg aagagcagcc cacttgttcc taatttactt  49020
          ggacccgggg gttcctgaag catgctgtga cctgtagcca tgcaacatac aatgtagcca  49080
          tgcaacatac aactcagtct tatctagatg tttctctttg gggctagctt ggctgtttct  49140
          gacctaaatt tgacactgtt tccgccttcc tttattttat tccactggaa aaatatccta  49200
          ggccaggcgc agtggttcac aacaccttgg gaggccaagg ccggcagatc acctgaggtc  49260
          aggagttcga gaccagcctg accaacatgg tgaaaccccg tctctactaa aaatacaaaa  49320
          aattagctgg gtgtggtggt gcatgcctgt agtcccagct acttggtagg ctgaggcagg  49380
          agaatcactt gaacctggga ggcggaggtt gcagtgagca gagatcacgc tacccaccgc  49440
          actccagcct gggcaacaga gtaagactcc atctccaaaa aaaaggaaaa agaaaaatat  49500
          cctaaatgtc tagacagtga ctattccttc aattccctac aaaatcaggc agttggtacc  49560
          cctttgtcta cgagctccca ttcaacaagg cgtccccatt ccccttcact ccggagcccc  49620
          ctggaggcag gggagcgcca tgacttagac gcactccagg ccgctccttg gtttcctctc  49680
          tgcaggactg cccaagaagt tcgtggacat ctttcagcag actcctctgg gcaggtttct  49740
          tgcccagctc catggagagc cgcagcagga acttcttcag tgttacttga aggatttcat  49800
          tctcttgacc atgcgtgtgt caacggagga ggaattaaag gtagatgttt agatactggc  49860
          taagggtcag gtgtagagct tgcatgatgg ggactggatg cagacacgga gacgtttcct  49920
          cagctgcctg gagctggtgc tgtgaagtct gggaacagaa catggtcagc gaagggtgcc  49980
          ggtgggtgaa ggggtcgccc agtctcctct caatattcag tgctacaccc tcagtccacc  50040
          gcccaggggc tcctaaaaca cggagctttc tgtgaacatg agaagacctc caatttcctt  50100
          gacatagctt ctttttaaat gttgagtttc tcttgaaaaa aattaaatac gtaactaacc  50160
          ctacagggta agaataaaca agtgaaattc aatagaaagt catacttttg actacctaaa  50220
          aattttaaac ttcagtacat aaaaaaggag agtgacaaat ttaagaacat ccttacagct  50280
          aatatgacta gaggttaata ttcttaggaa tcaataagaa aataccctaa gttttaaaaa  50340
          atgggtaaac gttataaaac aacaatttta taatctcatt aagcatatca acatccagga  50400
          aacatttgaa aaattgctta gccttactat taatagcaaa tcaacacaac agtttttaga  50460
          tatcatgttt acgtattcat tttgcaaagc tgatttttaa aaacaacagc cgccggccag  50520
          tgctgcaaag aaatagccag gccacgcggc tgacagtgta gcgtgcacag tgggcgccct  50580
          gcagggctgc gtggcagaac agttgagcac cttatccgat ctgaactgct gactctgtcc  50640
          tgaggaaact actggagatg tggacaaata tttggttcac agggatgtcc ttttcagctt  50700
          tgcttcgaaa aataagaaat agtttaattg tccggaaata caggatgggc aaattaaagt  50760
          atggccgtat gatgggttat tgagcagcca ttaaaaccat gtttttcaag tatactcagt  50820
          catagggaaa gttcatgatg tcatgttcag tggcaaaaag cccagacgac acggtgacct  50880
          taacgtggga ggagaggcag atagaaaact ggacagaagc aaacgggaca gaatagcaca  50940
          catggtttct aatttcctct tttatggttt tccaatagtt cggatttccc acggggaaaa  51000
          cataccattt ttgtaattta aaaatatatt ctaaaagctt ttttgaatcc cagtttctgc  51060
          agatggctct gtggtcctgc actaggaaac tgaaagcggc gtcagaagcg cccgaggaag  51120
          aggtttcctt accgtgggtg caccttgcct accagcgttt cagaagccgt ctgcagaact  51180
          tttccagaat cctgaccatc taccctcagg ttctccacag cctgatggaa gcccgttgga  51240
          accatgagct ggctggatgt gagatggtat ggccctcctc cgcctgccct gagcaagcct  51300
          tgtggtgctt ccaactccac tctgggaatg gagagcttct ggggctgtgt tccaagtggg  51360
          agatttcttc acaaggcaca taccttagct gaattcagag atgttaagga cacatctcgc  51420
          tgacgcttct cacatcctag acaatgaaag tttaggtcgc aagcctggga cacaagtata  51480
          catgcagcta acagccgggg cctctggtgg gccggtggga ggggcaccgc tcagccacgc  51540
          cctgctgtcc gtctccccag accctggacg catttgccgc aatggcctgc acggagatgc  51600
          tgacaagaaa caccctgaag cccagtcccc aggcgtggct acagttggtg aagaatcttt  51660
          ccatgccgct ggagctcatc tgctccgatg agcacatgca aggcagcggg agcctggccc  51720
          aggctgtcat cagggaagtc aggtgagacc caggagccct cacccactgc ttcatctggc  51780
          gcgcgctcac caggagcctg ccaagtgcca ggcatgtcca tgagaagacg ggcaggtgct  51840
          cctgccatgg gaggggctcc gtcctcaccc gttcactccg catttgccga acccttagtg  51900
          agtgccaggc gtctcattag ggtgctggag acacgagagg cggctgtgca ttcagggagc  51960
          gcactgtgta ctggggccgt agaaaggcag acgggctatt gtgatgccgt gtgagaaatg  52020
          ctgtggtaga aaggacaccc cgggcgggca ggtgcacaga gcaggacagg ccctcagggc  52080
          cagagtccac ttccctaaag gtgaggtggg acttgacagg cgcaggatca tgcagtgagc  52140
          gggttgtggt ggtaccccat gcagaggcat cacagtggga caccgagtcc cagctaagct  52200
          gagcgtctga gagcgagagc tgggggcggg ccaggaagta tgtcacatag ggcttgcttg  52260
          taatcccagc cgctgggcct ggaccccggg tcccgcatct cttctcccgt ctccctcctc  52320
          gtttcaccct tgggttcctt ggtgggagcc gagtgagtga gtgagtggcg ccctcttttg  52380
          acagagccca gtggagtcgg attttctcca ccgcactctt cgtggagcac gtgctcctag  52440
          gaaccgagag ccgcgtcccc gagttacagg ggctggtgac cgagcacgtc ttcttactag  52500
          acaaggtgag tacttgggct ggcctcagca catgcacgga tccacccttt tccgaaagga  52560
          agaacagcac tgacagtgat ctgcggctgg gagacgctct tttggctctg accgttttgt  52620
          ctagacatgc aaaggaaggt gatttcatca ctaggccatt acattttcca tgtttaattg  52680
          tttaattatt taccctctgc tgattgctaa gtcagagcat atcatttaga agtgattcca  52740
          ggaactgtgt gcagaaaggg gctgacgcag ggaacatgct tgtgaaacct tcggcaggga  52800
          ttacctggcc tttggagtga ccccagaaca gaccactagc ctggccatct gtggaagctg  52860
          ttaccatttt catagtcatg gagacaagga tgtcagagaa tgccaccggg gtttggggtc  52920
          ttcaaaacag tgctgtcaac agaaccaagg aacaggaagc caccatgcct gtcactcaac  52980
          acccttcata aagctactaa tgtggggtgg tctgcagaaa gaaacctgtg accctacagt  53040
          gatgcccctc tgtggccacg cagtggtgtc cagcaacagt ggccactcag ccaaacacag  53100
          cctcagcctc tgcctcaccc gcacccgtga ccttcacgtg agcacatcca gagccctcac  53160
          cgccaggggg tctggaagag gcagcgctgg ctgtccgacc tttggagcac aggaaggttt  53220
          actaaaagga ggccagcatg gatgctggat gtgttgactc tgacctatca aaacatcagc  53280
          ggcttagaca cagtatcagc tgatttccca cccaggatgg gtatgagcag cccaaggcta  53340
          aggtaccagc tccccggagg ctggcacgga gtcaggtgcc cacgctccgt cttgtccctt  53400
          cattgtccct aatgttcagc ttccaccccg tggcctggcg tcacagcctg tgggacagaa  53460
          agcaggggag gtagaggaca ggccgttttc cttaagagcc caatcccgga cacgcacacg  53520
          ccacaccagc tcgtgtctcg tggtcctaaa cttaggcact cggccttatc tggttgcaag  53580
          aaactgagga gtttttcgtg gcatggtcat gttccaggtg gaacttgagt tcttctgctg  53640
          aaggaaaagg cggagagagg atagtaggac acagccggtg ccccccttcc acccttttcc  53700
          ccacacccac acagcatgca gcctctccaa gtctcatcat gtctcggcgc tctgggagat  53760
          gcacagggct ttcagccagg tccagcgtgg gtcataaggg ccaggtgccc ataaacccaa  53820
          aggtaaagga gctggcccct gcctgctcac atgcccacag gatttgggag gttaggaacg  53880
          tggggagggt tttttttggc gataaaatgg cctcagaaac ttactgggtt tctggtttat  53940
          ttccttccag tcagatctct gtgcaggtaa ccacagccaa agaccttacc tcgttagttt  54000
          tcctgctgga agcctgactt gtacccctac ccagcccccg ctgaagagca gcccttggga  54060
          ccatttgaaa caagaggctt gggggaaagc cctgccttcc gccgtgaggc tggctccctc  54120
          ggccgggcag gaagttgtcg acggaactgc tgcaggatgg cacgggtggg actgcgggca  54180
          tggctggctt ttagttgttt tggatatgta ccttgaaggg gaattcctgg atcatttgat  54240
          aactctgttt aactttatgc agaggcactg tattgttttc cacgggggct gcagcatctt  54300
          tcttacatcc ccaccagcca ggcaccaggg tctgaatttc tccacatcat gggcaacacc  54360
          tgttactatc tgattttttt cataatggcc accgtgataa ttcattgtgg tttttatttg  54420
          catttctcta atgactagtt atgatgagca tccttcatgt gcttgttggg catttgctgt  54480
          cttctctgga gaaatgtcca ttcaagtcct ttgcccattt ttgaattggg ttgttgatta  54540
          acaaagttat taggatatta aaaatacaca catcacttcc aagtaagatt aatcccagca  54600
          attcaaggat ggctcaaaat aaaaaaaaaa aaatctgtaa atgtcatcag ttatataaat  54660
          taaaagataa actctatatg atcatttcaa aatgtagaga gaaagcattt gataaaatta  54720
          tttggaaaga aatacccttg tcaaacttgg aacaggaagg aactctcctt gagctcacaa  54780
          tgcccaaggt agacataata ttaagatgtc tataccaaca tcatgcctgc ccatcaaatt  54840
          ccattagtac agccattaaa ctatcttgta cagtgatgat gtgtattgcc taaaaaccag  54900
          tgtttccact tctaactata tcctagagaa acttctcatt tgctctcaga catatgcaag  54960
          aatgttgaat acaggactgt caggaattgc aaaaaaccta aatgcccatt aaccagcaga  55020
          caggtaactg gtgtctttat cagtgggtac aggagtgatc tggacctaag gtatcatgaa  55080
          gagaatgagt tgcagaagcc tttatacaac gtggtatcat tgatatcaag ttttaaaaca  55140
          ttcaaaataa taactccatg ttcagatatg cttacagcta tcctaaaagc agacatttag  55200
          aaatatagtt atctctgggg agggacggag ggatgtgaag ttgtaactat atgcataatg  55260
          ttttgtttct ctaaaaaatg atctatcgca gcagcttggg aggctgaaag aaaattttaa  55320
          aaaatttaaa aattttaaaa aatgatctaa agcaaatatt ccataaatgc tgagatttct  55380
          taaagcttgg tggggggtat acagatggtc attattatta cttaaagttt gaaatatctt  55440
          agtgagagcg gaggagacct taaaagaaaa agaagaggga aaatcgtaac ttgagaatgt  55500
          agtcccctga caagcagcat aatcacaaaa cgagcattca gagttcaagc gttaaacaca  55560
          ggatcacaaa ggcctcgcac cccacacccc acacacacgg cgcagccttg gccctgaatg  55620
          tggtgctccc tctgtcgccc ggcctggccg ccctcagccc tcccccctgc taatgactcc  55680
          tgtccctgcc tttcttcagt gtcttcgaga gaactctgac gtgaagacgc acgggccttt  55740
          tgaggccgtg atgcgcactc tctgtgaatg caaggagaca gccagcaaga ccctcagcag  55800
          gtgagacctt aggtttggat ctgtgaaggc gagaattctg aacctctcgt ggttttcact  55860
          tcttctggcc agtttctctg cttcagaact gattgccctt cttggattct aggtttggga  55920
          ttcagccgtg ctccatctgc ctgggagatg caaaggaccc cgtctgtctg ccctgcgacc  55980
          acgtgcactg cctgcgctgc ctcagggcct ggtttgcctc agagcagatg atatgcccct  56040
          actgtttaac tgccttgcca gacgaattct ctccagctgt ttcccaagcg cacaggtaca  56100
          acaccctttc tctcaagaaa gcatcctttt tttcattttc cttttttggc aaacacaata  56160
          ttcagaaata taaactctat taaccttcat ttggtagaaa acctgacctc agagaactat  56220
          cataagagac gccacttacg tactttcata aatatctggt atctcaagat tattctctcc  56280
          ccaagacata cacatacaga tttcagacaa caaattcaga ggaactaagc cagaaagtct  56340
          taacaaaggt cctcaccaga ggcccaagga atgtagacgc cagtgttttt tttttttttt  56400
          ttgagacagt gtttcactct gttgcccagg ctggagtaca gtggcacgat ctcagctcac  56460
          tgcaaccttc acctcctggg ttcaggcaat tctcctgcct cagcctccca agtagctggg  56520
          attacaggca tgcaccacca tgcccggcta atttttgtat ttttagtaga gacagggttt  56580
          caccatgttg gccaggctgg tctcgaactc ctgacctcag gtgatccacc cgccttggcc  56640
          tcccaaagtg cagggattac aggcatgagt gaccacacct ggccgacgcc actggtttta  56700
          atgcatcagt atcattcaca gtcactgacc tgaggatcaa cccacttctt gtctagcttt  56760
          ttggagctgg ttaaaagcag ctctggctct ctggactcag caggcctcag cccggctctg  56820
          tgagtggttg gttttctttc cttccccttc cccccttctc aggcctccta aaagtggggc  56880
          accaggcaag cccagtggat gggttctttg acatactttg ggatattgaa gggtattgtt  56940
          gccgggtcca aatgatcaaa gtgtttccag aaagggatgc atgtaaatat catctgctga  57000
          ggttttgaag actagctcta acgggtgaga ggagtgactt gaatctttca atttaaaagt  57060
          aaaatgccag ccaggcatgg tggctcacgc ctgtaatccc agcactctgg gaggccgagg  57120
          tgtgtggatc acctgaggtc agcagttcga aaccagcctg gccaacacgg tgaaacccca  57180
          tctctactaa aaatacaaaa ttagccaggc gtgatggtgc gtgcctgtaa tcccagctac  57240
          ttgggaggct gaggcaggag gatcacttga acctgggagg tggaggttgc agtgagcgga  57300
          gatcgcgcca ctgtactcca gcctgggcaa caagagtgaa actccgtctc aaaaaaaaaa  57360
          aaaaaagtga aatgctgtgc aaatctcaag tcattctgta aggaggcatt tgggaaacac  57420
          catccacctg tcttctgttt ctcgtgttct aagggaagcc attgaaaagc atgcccgctt  57480
          ccggcagatg tgcaacagtt tcttcgtaga cctggtgtcc accatttgct tcaaggacaa  57540
          cgctccgcct gagaaggaag tgattgagag cctgctctct ctcctcttcg tccaaaaggg  57600
          gcgcttaaga gatgctgccc agagtaggtt gctttcttcc tgtaaaccta gcccctcatt  57660
          tcttcatctc gcttctgcat gtctcatgca gtgagctgcc tttttctttc tggtttaagg  57720
          acactgtgaa cacacaaaat ctctctctcc attcaatgat gttgtggata agactcctgt  57780
          catccgctca gtgatactga aactgctttt gaagtacagg taagaacaac atggagactt  57840
          gcttctggaa agccctggct ttttctcttc atcgcagcgt tttgttacca agtcttcttg  57900
          tcgtgactag tagctagtac atgatcttgg ggagcttttt cggtgagaca cagcctggtt  57960
          acttgtactg gttgtgtatt ctgacatttt cacatatagg cacatgagtt tagtattccc  58020
          acaagcacac gcatctagca agaagccaac agtgccgtga agggaccaca gtggcgtgag  58080
          ggacatggaa ctcaagaggc cagaatctgt ggtgctgagc ctggttccac agcagcgcaa  58140
          ctttctgatt tttcagatgg tagcttagaa tcctgctcac cctgaatgtc ctagatgtct  58200
          cctaagtttc tattcccctg aacatgggct ctatttcctt ggaaaggatg ttgacatcca  58260
          agaatagtat cacctgtggt acttgtatgg atctaatatt gcagttctca aagtgttggt  58320
          atggaccctt gggtgtgagg taggtctctg aggttaaaac tattttaaaa attagattac  58380
          taagataaat ttgccctttt ttaaaaaaca tgttgatact tatgatgatg ttacaaaaag  58440
          cggtgatgag ttaaactgct ggcccctcac gtgaagacac agtagctgga ggtattgttt  58500
          tcttcaccgc catgcacacg tggttttctt catgccagtt tcattttagt tttactaaat  58560
          cttgactctt gaggatttga cttttcaacg ttttgtggaa atgggaagca cacacaaaac  58620
          actcccacta cacaccggag tagacagttg cctcacagaa aatcactcat gacaagccct  58680
          gggttatcag ccggctgctg tgttcatgga ccgccacccg tgctgggagg aaggatgcac  58740
          atgatacagg tgtccagggc tgggcaggcc tctcctggaa atcagcaaag tgagccagcc  58800
          tcagccaaac aactgacaat gttggttggt gatgataaca ttcaagcttt taagctgaaa  58860
          ttaaaatttt gaaaagctta tattctccac tatgagcttg tgagcttttg aatacttaaa  58920
          gacattttgg ggcaatttgt ggtgatatta atgaatatgg attttttttt ttaaaacgta  58980
          gaatacaaat gtgtcaacct ttacaagacc tgcacagccc agtgaaccaa tattttccaa  59040
          atgaccaatg cctgatgtca tgaaatcatg tgggtcaaaa aagaaaaaaa tctatttaaa  59100
          gtatgggcag acctttttga ttttaacata attgactgaa aaatgcactg atacagtttc  59160
          aggctccaca ttgcaactaa cctctagaca tgaccattta tcactgtggg cacagcatta  59220
          aggaataata gccacaatca gctgcaaaaa ctattaaaat gttcctcgct attccgagta  59280
          tatgaggaca gattttcttc atgttctccc atatgctgca gcgatgggga gcagggcagg  59340
          caggccgctg acttccagga gccaggcccc agggccagca caggaatgga agaccaaacc  59400
          actcttctca cggattcatg ttttggaaaa tattttaaat gttatttaac atgtaatagc  59460
          tttattgtta ttttaaatga atgtatattt ttgaaacctt ttgtttttaa tgtctcataa  59520
          ttcctaatat cataaatatt gataatataa cccacataaa agctcttcgg ggttctcaat  59580
          ttttaagact ataaaggggt cctgaaacca aagtttgagg acagctggtc taaaatgtga  59640
          gttttatatt cctccagtat tatgctaaaa ggttttccat aaaatcttag aaaccacgta  59700
          tatgtatgta tatgtttata cacacacaca cacaggacag acgaccgata gatagatgct  59760
          ctttttttta gtaaggtatg tctccagatc tgagagaacc aggaataata tttctctttc  59820
          tgcagctttc atgatgtaaa agattatatt caggaatatt tgaccctgtt aaaaaagaaa  59880
          gcattcataa ctgaagataa aactgaactg tacatgctct tcatcaactg cctggaggta  59940
          agtgaactct ctcttccctg aatttctttt ggaaactatc tgaaccacat ggtttaaaat  60000
          ttacagaata taattttagt cagtataatt aacgaatgct ctgttccgtg cagaaaagaa  60060
          gaaaggtttc aaagacgcgg cttctgcctt cagcaacgta tattttggca tttacttgca  60120
          tatacataca aaacagaaca gcctaggaga atatactgcc aaagttaaca gtggttatca  60180
          ttgagtgggg acattatgga tactttttat cttcatattt ttatatccaa aatttttata  60240
          atgtaaataa attagataat tttttttcct cataggttca cttttcccct ccttcttgtc  60300
          cttaaaataa aaaggaatgt taggtttcca taagtcaaga aatttacact gaaacctaca  60360
          gtaacattct tctatccttc cttctccaca gtcacattgg cgactgtaga agcttggggc  60420
          atccatgttt aaaaaaataa tatccttttc tttcttgttc cttgttcctc aggattcaat  60480
          acttgagaag accagtgctt actccagaaa tgatgaactg aaccacctag aagaggaagg  60540
          tcgtttcctt aaggcatatt ctccagcaag ccggggccga gagcctgcca acgaggcctc  60600
          ggttgaatac ctgcaagagg tggcccggat ccgcctctgc ctcgacagag ctgcagattt  60660
          cctctcggag cctgagggag gcccaggcaa gtcttctctg ccttgctttc ctttgggttt  60720
          aaagactccg ttatttagaa attcaggaag tatgggaaac tagttcttcg aatagactac  60780
          tactgggctt ttctacatcc cctctcccct ggatgtgttt ctgtgaatgc ctgtgggtag  60840
          gtccgatgcc ctctggttgg ccttgtgtcc tacaataaat gccctaagtc accagccact  60900
          cacccgcttt ctcgttggcc tctcagagat ggccaaggag aagcagtgct acctgcagca  60960
          agtcaagcag ttctgtatcc gggtggagaa cgactggcac cgggtgtacc tggtgcggaa  61020
          gctcagcagc cagcggggga tggagttcgt gcagggcctc tccaagcccg gccgcccgca  61080
          ccagtgggtg tttcccaagg acgttgtcaa gcagcaggtg agaagcgggg ccgggcagca  61140
          cacaaacatg cacccccaca gccccataca ccccaaaccc acacaccccc ctaccctcac  61200
          accctacccc ccccacaccc caccccctca caccttcccc accacatacc ctcatacccc  61260
          cacacctcac cctcacaccc ccacacctca ccctcacacc cagggatggt gccactgctt  61320
          ccgcgttccg cctgccctta gcatccccag agccaggaag gaaacctgcc gcttgtctgt  61380
          ctggtccttt gtctctgtgc ttcagctgat ttgccccagc ttgtgatcat gtttacactg  61440
          cctgctgtag ggccaaggtg agggcactca cctcagagct tctttaatta ggcatcactt  61500
          ctaattgaat ttcactcaag gaaagtagaa cattcttgtg gcctttgctt tcagcgaatt  61560
          aaacgtagtt cagcttgcaa ggtgcgacct ttttacctct ggcaggcaga gacaggcaag  61620
          agcaagaact aggaatagaa gaattgcaga agaggcttca aggccaggct gggcacagtg  61680
          gctctcacct gtaattccag cactttggga ggccgaggca ggcggatcac ttgtggtcag  61740
          gagtttgtca agaccagcct ggccaacatg gtgaaacctt gtctctactt caaagaaaaa  61800
          aaaaattagc tggacatgat ggtgggtgct tgtaatccca gctagtcggg aggctgaggc  61860
          aggagaatca cttgaacccg ggaggcagag gttgcagtga gccgagattg caccactgca  61920
          ctccagcgcc tgggcgatag agcgagactc cgtctcaaaa aaaaaaaaaa aaaaaagagg  61980
          cttcaaggcc tctcagtggt cctttccaga tacccagaaa ttaacaaatt cttattgtcc  62040
          aggggataca aaaatggtac taagaacccc ggcactgttt gactaccacc tggggtttag  62100
          agttgacatg acttgagcca cccggcctca ggtgtggtgc ggtgcgccgc aaacggagga  62160
          agcaagcacc tccccaggta gcgctgccgt cggcaggcat tccctgcact tgcacctctt  62220
          cgtctactga ggaggaagct ccctgcgaag agggcaccag actgtcctgc ctcaggccag  62280
          gtcagggaat cccagcttgg ctgcctttaa acctcgaatg atcaaccacc tggttcctgt  62340
          acccgttcag acggttcttt gcaagacatt cctcccattg ttcaccccca actaacctct  62400
          gtattccagg ggctgcggca ggaccaccca ggccagatgg ataggtacct ggtgtacggc  62460
          gatgaataca aggctctccg tgatgctgtg gccaaagctg tcctcgagtg caagccactg  62520
          ggcattaaga ctgctctgaa ggtaggatgg gcccgtggct tctctctgat accaggtggc  62580
          atcccttgga gcctgcatgt tccctggttt atgtcaaatg atgcagggtg atggaccact  62640
          gatgcagccc atcacgtgac actgtattgg aagtcacgtg cccacagcct ccagggcgca  62700
          cctggctagt gtgcgtgaac cagtggctgg aacaggacag ctatgacagt tgagctgggt  62760
          tgacagattt gctgtgtctt gctgatctgc caagtccatc agcagcgcct tttgatttat  62820
          gcccattact tcctttgaga ccctgctgga aaacagtcta agaaagatgc tgacacaact  62880
          attaatagca aaattcatac ctagatgtat tcataattca gatatgcatg tgtgtttaat  62940
          aaaaatacat atgttggtgt agtgtgggaa gttaaaaaat ataaagatgt ttttagaatc  63000
          taacctttaa attggtctgg tcttgcttcc tttttgagtc cctgtgccag gaaaagagga  63060
          aatggaaaat cctctttctg ctcagaagtt tctaagacca gtgaaggagt cagaagaaca  63120
          gatggtgatt ccgttgcttc tgtcattaag ctggctgcta aatatgcgtt gagtttaatc  63180
          tgagagtatt tcaggaactt tgtagcccaa aagttgctcg ccagaagact gcccatgtgg  63240
          ggcatgaccc caggtgtcca ggcctggaaa aggctccttc ccttttggtg ggttgagggc  63300
          tgaggcatgt gaaaagtttc ttttcacatg caaacttcgt gggcctctgg cccttaggta  63360
          gatctggcag gcagcggtgc gggggcgtct atcctataat cctagcactt tgggaggccg  63420
          aggcatgcag atcacaaggt caggagtttg agaccagcct ggcaaacatg gtgaaacccc  63480
          gtgtctacta aaagaaaaaa aaaaagaatt agccggacat ggttgcgtgt gcctgtagtc  63540
          ccagctactc gggaggctga gttagaatcg cttgaacccg agaggcagag gttgcagtga  63600
          gccgagatca tgccactgca ctccagcctg ggtgacagag caagactcca tctcaaaaaa  63660
          aaaagatgtg ttgagctttt aaattcttac ttgataccct tgattttgca ggcctgcaag  63720
          accccccaaa gccagcagtc agcctacttc ctgttaacac tgtttagaga ggtggctatt  63780
          ttgtacagat cccacaatgc aagcctccac cccacgccag aggtgagtaa ccgcctgcag  63840
          ggctgtgttc aaagtctcag tatttggagg gattttattg aatagaatga aagttatcaa  63900
          cacaaatcat accataattt ttttatctag gatagaggtt ctcaaccttg ttatgtggag  63960
          gaacacataa ccaagctgtt taacccaaag cttgtagaat tataatgaaa actaaagcca  64020
          agaacataag ataatgttta acagaataga atatcaaaat taatgcttac gtatgtggat  64080
          gctgtgtttg tatatgcaca attctcttct ctgaaaaatt tccccctcaa atggtggtga  64140
          tttctccata tttaccttga tatttgatgt gtatttggtg tcagtgtatg tctaagagca  64200
          attcacacaa tattctttga tacatcttaa tgttaagttt ttttcctgtc agcaatgtga  64260
          agctgtgagc aaattcattg gcgaatgcaa gatcctttca cctcctgata tcagccgttt  64320
          tgcaacatcg ctcgtggaca attctgtgcc attgttgagg gcggggccta gtgacagcaa  64380
          ccttgatgga acggtgacag aaatggccat tcatgctgca gccgtccttc tgtgtggaca  64440
          gaatgaactc ttggagcccc taaagaatct ggccttctcc ccagccacca tggcggtaag  64500
          agtaggccac aattccatcg gccttcactg gaacaccccc cagagcttgt cactgtagag  64560
          accgagctgc agctgtggga actcttgagc atctttatct cctcagttct ctgcctttgt  64620
          gtcacctgat tcttgagcac acaagatagt gacagacttg ccttgccctt tgttatttca  64680
          caggaagctg ttctgttttc ttcacagaca gcttgagaag tccagcagaa ggaaagcaga  64740
          gttccctttc ttcctctagg cctcctgctg agcagcagca cccaggtgac aagctcactt  64800
          atctagagct gtctctgtct tcttgttttt cagcatgctt ttcttccaac catgcctgaa  64860
          gacttgctgg ctcaagctcg gaggtggaag ggtctggagc gagtccactg gtacagtaag  64920
          tgttggggtc tagatgaccc cacactcctt tgagcttcaa agggtgtcca gatgctatga  64980
          agcattgggt tcgacttggg gtccacgtgg tttgtgcctc agggtccaaa accacctgca  65040
          ttctaccggt ggcgtctgca gaagacgaat ggcttgaagg agctggcact ccgccggcta  65100
          gatgatccaa accatttcat ttctttgtcg tgtggaaaag gccctctgtg atgcacttct  65160
          gttctctgga atatgccatt ttgggagaag ggagggactg ggaaccacat cagagacgca  65220
          ttcaaaggcc caccacaaaa caaagttttt gacacaaagc tcttctgaaa tatatgaaat  65280
          atagaaccgg gagactgact catataaccc atgacatgta aattttgctg ttgcctgagt  65340
          aaatatttta aaactagttt ttaaagttgt tataaaatat gctcatgaca aaaaaaaaaa  65400
          aatcaaggaa aatagaaagg tctagaatcc tgtccacctt gcctccaaaa gtacccctgg  65460
          tatgggccta tattctaatt gctctttact tgataaaatt aataaaatta gactcagaca  65520
          tttttcactg acaacataca tttattaagc ttcaggcagg tgtcatgtaa cttaacaaat  65580
          tagcgtggga tgctctggac agtcattctc atattgtggt cagggccaga gagtagagag  65640
          ttagctttcc cttttcaatg tgggtcattg ggtgaaacct cattagccaa tgtgtgtcct  65700
          gttctcttca cagcttgtcc caacggccat ccttgctccg tgggagaggt gagtcttggt  65760
          atttaagata gggtttgagg ggtggcgtgc actcctgggt tggaggaggg ggatcgtggg  65820
          tcaggagagt gaggctctcg gccttccagg agagcacagg ctcaccgagg actgcccagg  65880
          gtgctctgag cagggcaatg ccaatggcgc taagggtttc tagcccaggg cttctcagac  65940
          tcagcactgt ggacgtggct ctgcggcgtg ggctgtcctg tgcactgcag gctgtctggc  66000
          agtatgcctg acctcgagtc cctggatgcc aggagcaccc actcctccca gtgtgacagc  66060
          taaaaccaga cattgacaaa ggtcccctag gaaagaaaat tgctactggt tgggaactgc  66120
          tgctagccat tctttctagc cactgcagca tggggtcagt gagccttgtc ttgatagaat  66180
          ggcaaggtgt tgcctggacc acaggctgca ttattagccc tcagaggagg tgtggtccag  66240
          atgccaaagg aaaaagccac gtgtaggctg tgcgccatgg gggaagaact gttgattatt  66300
          cctctctgga ttcccaagca tctagcctag agccctccat acacagtatc tgtacttgct  66360
          gagcaagagg ctggtgggtt gagctgacac gtggtagtta gttattagta ttacttactt  66420
          ggttgagata tgtctggctc tcttacccag gctggagtgc agagtgacat gatcatagct  66480
          cactataaac attgaactcc tgggctcaag cgatcctccc gcctcggcct cccaaagtgt  66540
          tgggattatg agccactgtg cccagcctga tacacgtcat ttaataatgt atataagaga  66600
          tacggaggga gaaaaactgt tacatacact tcatttttct gagcttcaat cacttccttg  66660
          tccatgaaat gaggacgctg aaatagagtc tatccaagaa tgctcccagc tctgaaattc  66720
          tgtaactggt ttggtgtgtt atcagccgtg actctcagta tattgtggca caatatctga  66780
          ttttgaaaaa taagcctttg gaagtagatt atgtgattag atttttttaa ataaaaaagt  66840
          ccaagccagg tgtggtaggt cacacctgta atcccagcac ttcaggaggc tgaggcaggt  66900
          ggattgctag atcccaggag tttgagactg gcccgggcaa catgttgaaa ccccgtctct  66960
          acaaaaaaac acaaagcatc agcagggcat ggtggtgcat gcgtgcatgc gtgcatgcgt  67020
          gtggtcccag ctacttggga ggctaaggta ggaggattgc ttgagcctgg ggaggtcaag  67080
          gctgtagtga gccgtgatgg tgccactgca ctccagcctg gaggacagag cgaggctctg  67140
          tctcataaaa attgatatat gaaaaagtcc aaatgaatat aaggaagtca gtttggaagc  67200
          tcttctagta ttcttggtat tagatcatga agtgccacag gctagtgtga tagatggagg  67260
          gatggaaaaa gtgctgaata caagaaagga aggttgaatt ttatatattt gtctataaag  67320
          tgtcactctg ggaataaagc ttaaattgtc tcacttattt aaaaaacagt tccagtttgc  67380
          ccacgtgcaa cattagtgag tacctaccct gttcccatgg gttctccacc cacccgaaac  67440
          aagcacacac tgggacaatc tgagggtgct cacgtctgcc ggtgataagg aggtgttcat  67500
          ttgcatgatg gcatttgtgc ataaaatggt actgctccag aagtggttct agtgccctgt  67560
          cttcacccta gtgtggcagg ccgatggaac agagcatctg cattgactgc catgcgccga  67620
          ttggaggcat tgaccacaaa cctcgggacg gctttcatct ggtcaagtat gtgggtcagg  67680
          attctatttc ctaagtactc aaactttggg gtgttgggct gtttttattc cagctgataa  67740
          agtgatactc aagatagtac taattactcc agtacatgtg ggcctgtgtc atattgaata  67800
          gcaatgccaa agtcccagca gtcacacagc agggaggcat ctgatctgtt gttggatccc  67860
          tgggccctga aatgcaaagc aggctaccct ttaacagctg ttaatatgaa tacaggtgtc  67920
          ttccttttgg gccttgggtg caccttctgt agaaatatgc atgacataaa cagatgatct  67980
          aattcacgag gacatctatg tctgcaggac caaaacctgg gcatccgtct gtctcagcag  68040
          atgccatctc acttgccagc aatcttagct ttctccattt tttatttttt gagaaaaatg  68100
          aaggagacag acatagtctt atgaaatacc agacttcaga atccaggtac aaatccgatc  68160
          ccacaatccc atgctgagat gaatgtggtt ctaaatgctc ctttcagaga gtgagtggga  68220
          cctgcgtggg ggcctcacat tctgactgtt ccctgcagtc acagcttaaa atactttcat  68280
          gttatctcca gaaactgtca cagtgtcctc catcctctaa tagttttgcc actgagagca  68340
          tcggccacac tgcatctcct ctctgccgga ctttagatcc cggtttttcc tttggggaga  68400
          tgagaacaat atggacaccc atgggatgcc gactgtcctc ccaaactcta gctgttctta  68460
          gcccaaccgc tcctctcctg acaaagactt cagtggaaaa gacgggtcca ggcctgcgtc  68520
          ttaacaccct gcccggggat cagcatcaat accacacagc gcagccacct gacgctgaga  68580
          atgcggtcgg gtctggtcca ccggaaaggc gagtctatca tgagagagac tcttaggaac  68640
          atggtccagg ctttgtggaa cagcaagtac tcttcacata actctcttct cagccgtaag  68700
          cctcactcca agtgctgaga aagtgcagcg tgccaaagcg gccagcctca gcctctgtct  68760
          tgtgttctct cgttctttcc agagacaagg cagacagaac gcagaccggc cacgtgctgg  68820
          gcaacccgca gcggagagac gtggtgacat gtgaccgagg gctgccccca gtggtcttcc  68880
          tccttatccg gctactcact cacttggctc tgcttctggg agcgtcccag agttcccagg  68940
          tataacccag tgctgccaaa caatgggctc agttaagaac ctgctttcgc ttcttcccag  69000
          ggagtccttt tgtcttgagt cctagctgcc atctatgcgt tttggagata attagtctac  69060
          aaagtaatat acaagttata catcttcatg tttccccctg tggcgtatga tggtatgggg  69120
          ggaactactc cccagattat acagaatcca cttcaaatta acactctgtg tctctggtcc  69180
          acatctggga gtagagaggc tgacatcttc attattttac ctgtgtcttc attgtagcta  69240
          gggaagaaag agcacactgc ataaccaaga tggccaacag tacaatctgg atattcttta  69300
          tctcactgta acaacagaaa agccagcagc cgttccgctt gctagccttc ctttcacctg  69360
          gatcactccg ccgttttcat cttagaaacc gccttccgac tctatgctgg tgctccactc  69420
          ccaatggcct ctaccaggct caccatcttc tctacaaacc agatccccgc tgaacactct  69480
          gttccgttgc ccccacaggc tctgataaac atcattaagc ctccagtgag ggatccaaaa  69540
          ggctttctgc agcagcacat cctgaaggac ctggagcagt tggccaagat gctgggacac  69600
          agtgccgacg agaccatcgg cgtggtccac ctcgtcctgc gcaggcttct ccaagagcag  69660
          caccagctct ctagcagaag tgaggaaagg ggcaagggct gggcggggat cacacagcac  69720
          aacggcagcg caagcaggct cgctgtcttg tgggccaccc cacacacagc cagtctgagc  69780
          tctgtctgtg ctgttgctgg aaagaatgag agaacacaca gagagaaaac cgtgtctagg  69840
          gaaggcgatg cctggggctg gaaaaaggaa gcactctgct tgcccagagg ctggaaggag  69900
          ctgctctgtt ccctccattc acccctgcct ggctaagacc tgcggtattc gggagcgtct  69960
          gcacgcaagt gttcagtgtg catatatggg gagtcttcag ttccgaagtc agccccgtag  70020
          gtcattcccc taccatgctg ggagcacgtg tcgtccacac agagcgtgcg tgtcaaagga  70080
          tcaatcacca tcacagttgt gtgctgattt attaaatgtt tatatgtcca cagttatgtt  70140
          aaaaaaaaaa agctataaaa tattgtattc actgagctaa ctttctattt taaaaattta  70200
          aatccataca gaaagaaaag gtctgtaaga caacttagta aaatggttat atggttatct  70260
          gtgagtggtg gaattaagag tgattttctt ttgctaatct gcaaaaatca caatgaccat  70320
          tgtgaggaca atgttaattt aaaataataa caataatagc aagaagaagt cctgccccat  70380
          gacaagaaaa tctgctccca cctcaggtac ttctttgcct gaaactggca ttcctattta  70440
          ttttccattt tgaacaatct gattttattt taagcctctt attctggtgg gatttcagca  70500
          aagtgagcac acccagagtc acactgatga aatgacagaa tcctggaagc aggtggacag  70560
          ttcccgcagc actccacatc tgtgtggtct gcctcagggt ttgggtggca gcagctgaga  70620
          cggctggcgg tagcctgggc cactcttact attgagctca agttctgttc tttcagtaat  70680
          ttttttcaaa atgggtctaa gattacaatt atgtaggata gaggaatttt tagagattga  70740
          tgttatcttc aaaaggtcat taagttggtg gtaacaacag gaactacttc aaaatactta  70800
          gattaattta gaaagctatt acctcaaaac gagtgttatt tctattaaac acttatttag  70860
          ggtttattat acgcagactg ctgtgttctt tgtgccttgg gtaacctaca catttggagt  70920
          ttttttgtag ggcttttaaa ttttgacaca gaattgtcaa ctaaagaaat gaggaacaac  70980
          tgggaaaagg aaatcgcagc tgtgatttct cctgaactgg aggtaagcag taagtgctga  71040
          cagctgggtt gctcctcggt ccagaaagga agggtcccgg cgtctgctga atgctccttg  71100
          cctgttgccc ctcgtagcgg tgccagcaag agcctttgac tgagccccag attccaatgc  71160
          tccccacctc gagtcactcc atcctcctcc tgtccccaag tgctcttccc tcctacagct  71220
          ggtcatgaag tcagtccgag gaattcctgg gaatccagca agtgcaggca gtgtttttct  71280
          ctccattact ttttacagca gaatgtaatg tacgaggtag agaaataaac tatcacatat  71340
          atacccatta aaaatgaact gacaatcata gattaattat tcatctagca gccagaatgt  71400
          tagtaagaga aatataggtt tctgaatctc attctgtttg gggagacata catctataaa  71460
          caaacaacac tgaaattaga agatcaaagg gaatacctga ttacatgctc agagcagggg  71520
          acaaacgccc taatatgcag acacccactg gtggagttac tgggtgttac aatctgtttg  71580
          tagcaatacc tcacttccag aatttttttt ttcattttct ccatccagca tctagataaa  71640
          acccttccca ccatgaataa tctcatcagc caagataagc gtatcagctc taaccctgtg  71700
          gccaaaataa tatatggtga cccagtgacc ttcctgcccc acctgccccg gaaaagtgtg  71760
          gtccattgct ctaagatttg gagctgcagg aaaagaatta cagttgagta cctccagcac  71820
          attgtggaac agaaaaatgg caaagaaaga gtgcccatcc tctggcattt cctgcagaag  71880
          gtatgtctgg cttactgtgg ctccctccct ctttcggtgc agagttcccc agcaggcctg  71940
          aaggccctgg gcttttacgt agtataatca ttcttaacag actattccag tgctttggtt  72000
          ttgaatagga tgtagcagaa gactcagggc tagagatctt catacatatc aaactgtatg  72060
          attgccagaa gcgtaaagtc acagacgaaa tacacaccca cgttgggatt agcagtgacc  72120
          tgtggggaag ctggaggcca ggagaggacc tcccctcatc actcagccag acagaaaagg  72180
          atgcagctct ttcccagccg ctctgttcct ctctgtccac aatgctggag catgggcaga  72240
          tcaaacaaaa ctcctccctg tgcctaagca tcgaggcgta cgtggaagac gggagtgagt  72300
          gggtgtgtgc cggcggtgct ggggtactgg ggagcagtca agtgtactgg ccacatctgt  72360
          tggaattgga aatatacttt cctaactttc acccatttgc actttcattt tctacaacac  72420
          attgtctaaa catttctctc catggactat tatttgctgt ctagcaagga tgaagacgag  72480
          ttggaaactt ctgttggtca gttgaggagt atgagttcac aatgacagga aggacttcct  72540
          gtcaatactg tggcctctct ctcagatgca gtttcactac gtcgaagatg cttagatcct  72600
          aggtcttcgg aaggacaccc aggaataagg ccagccctcg ctgcctaagc tctgggtctc  72660
          ttctttcagc agcttctctc cgtacccagc cagttacatg ggcccaaggg acagatttcc  72720
          ttcatcagcc tttgatggac gcggctgatg cgtcagctcc atagaggctg ggctccctct  72780
          tcgccgccct ccatttctag cacactgcac tgtctgtaga cttgtgggaa gaacttttcc  72840
          cgttttcaag ctccacgctg catcacagga aatgacactg accagattaa gctacaaata  72900
          caagtctcgc agccagtctc aaagtctgta accccaataa cattttttag gtaaataaaa  72960
          attgttactg ggtggtcttc ccttctccag gaagcagagc tgaggctggt aaagttcctg  73020
          cctgagattt tggccttgca aagggatcta gtgaagcagt tccagaacgt ccagcaagtt  73080
          gaatacagct ccatcaragg cttcctcagc aagcacagct caggtgtggc tctgctctga  73140
          caggaccagg actgtcccgc atttggcggt tcgaaaggat cactgcatag gggaacaggg  73200
          tggggcggag gggaggaggc gctgatgggt gctctatagc ctaagccctt accatgcggt  73260
          gaagggtgct tgaaccccaa aaacatatta gaagctttcg ccacagctga aaagcacctc  73320
          cctctctagc tcctcaaact cggctcactc cttcaaacag cacctcagac atgcttgtga  73380
          ctgcacaaag caggaaagat gggctctcgg cagagcatgt aactagggtg gtttggccct  73440
          ttcagggggt tgctatcata cggttcttac caagtattct gttcaacaga tgggttgagg  73500
          cagctgcttc acaacaggat cacagtcttt ctgtccacat ggaacaaact gaggagatcg  73560
          cttgagacga acggttagta tcctgtcccc tgtaccacta agcgttccag gagagcctcg  73620
          tctgaaagct cttctcgtca gcctgactcg gcccatccct gtcaacaccc agcactgtgt  73680
          ttgtttgttt ttgagatgga gtcttgctct gtcgccaggc tggagtgcag tggcaccatc  73740
          tcggctcact gcaacctctg cctcccggat tcaagcaatt ctcctgcctc agcccctagt  73800
          agagacaggg tttcaccatg ttgcccaggc tggtctcaaa ctcccaagct caggcaatcc  73860
          acccgcctcg gcctcccaaa gtgctaggat tacaagcggg agccactgcg cccagccagc  73920
          actgttaacg cttaacttgt gtctcttttg atggtggtgt ctggataagt aaaataatgt  73980
          gtcaggaaaa taaaccctca gtactcttca gtccctaaat atggcatcaa aagggagctg  74040
          aaagcatttg aaactctatc agcatatgag atggggcaga accgagaccc ggctcccggc  74100
          tgtgtgtgga gctgatggct tctgcatccc tcctccccac gcctagattc tgtgaggagt  74160
          tggaactcct ctctgcttaa gcataaccct gtcgtttaaa ggtgagatca acctacccaa  74220
          agactactgc agcactgact tggatctgga cactgagttt gagatcctct tgccacgccg  74280
          acggggcctg ggcctctgtg ctaccgctct cgtcagctac ttgattcgcc tacacaatga  74340
          aattgtctac gccgtggaaa aactctccaa ggaaaacaac aggtttgtgc acgagccacc  74400
          aggaagtggt gcctgctcag cccagagtcc ctaagcccag tggggcagac acaagcaagc  74460
          ttcagcccct tccctaacag acactcactc cttcagccgc ccccaccagt gacccgcccc  74520
          atacttgggt agggttttcc actgctccaa ctgtgagaaa tgggagcctg ctccctgcaa  74580
          catagagccc taggcccgca tgcctggcct ggacgctgag cgctgtcttt ctgcccctca  74640
          gctattccgt ggatgccgcc gaggtcactg aactgcatgt catcagttat gaagtggagc  74700
          gggacctgac tccactgatt ctctccaact gccagtacca ggtggaggag ggcagagaga  74760
          ccgtgcagga gttcgatctg gagaagattc agcggcagat cgtcagccgc ttcctccagg  74820
          gcaagccccg gctgagcctc aaggtagggc tgactcctgc cactgctgct catttggtgt  74880
          gtctgttgtg aacaagcagc ccttggtgtg tttctcgaga gagggaagca gcacctcacc  74940
          ctgcagtctg gtctgtatct cctccctcac acctgcagct cccgaggcca ccacgccacc  75000
          tgtatctccg ggccgcaggg ctctcctgag ccctctcctg cagggccatc tgcacctcag  75060
          tcccccaagg aactgttgag gtcttttttt gaaacagggt ctcactctgt caccgaggct  75120
          gcagggcagt ggtgccaagc ctccacctct gggctcaagc gatcctctca catcagcttc  75180
          ccaaatagct gagatcacaa gtgtgcacca ccatgcccag ctaatttgtg tattttttgg  75240
          tagagatggg gcttcaccac gttgcccggc tggtctcgaa ctcttgggat caagggatcc  75300
          acccgcctag gcctcccaaa gtgctgggat tataggcgtg agccactgca cccagctgat  75360
          tgttgaggtc ttgattctac cagttaatgg caccaccacc cccacagccc ctcttccttc  75420
          agcctccatg ggtaacctgc cagcagatgc cattagctgt gccttctgtg tgtcctcacc  75480
          tgactgccaa agcccaccct gtagttaaaa gcatcctgta cgttggactg ctagccactc  75540
          ctaactggtg cccacctcca ggttcttcag tccacggcct aaaacccaca tctggctctc  75600
          ttcatcctgt gccggatgga cctgcctggc ctctcatggc atatgggata aagccgacac  75660
          tctgttgtct ggtatgggag gccctgtagc tcggcccagc ccaaccttcc agccctgcct  75720
          ccagccactt agcccatttc cctgaactgc atcccgtgac ctcatgcact gaagccacac  75780
          agcaggcact ttcccatctc tgttctttga ctggacgcac ttgttccttc cagctgcagt  75840
          catatctact gtacttatgt acggtaccac ccgcaactgg gccaggaact gtgagagccc  75900
          atggattttt tttttttttt tttttttttg agacggagtc tcgctctgtc acccaggctg  75960
          gattgcagtg gcgcaatctc agcttgctgc aagctccacc tcccgggttc actcatgcca  76020
          ttctcctgcc gcagcctccc gagtagctgg gactacaggc gcccgccacc atgcccggct  76080
          aatttttttg tatttttagt agagacgggg tttcaccatg ttagccagga tggtctcgat  76140
          ctcttgactt cgtgatctgc ccgtctctgc ctcccaaagg ctgtttttaa ttcattctca  76200
          cagccatttc ctctggcaga gtgactgcct gtgcatggtc tgtgccttta gtggctgaat  76260
          gaataaatga atgggatatg cacaaatacc tgttgcccta gcgcctcctg tggcgaagca  76320
          ggccacgatg atgtgacaat atcttgtcat gtaattggct gtgaggactc cgctggattc  76380
          ccggttgtgt tactatttcc atagatggtg ggttaatgac ggagaggggc gctcttagcc  76440
          aagggataca cagggcagcg cggcactacg ctgcagtttt ccggctgcag attctgtttg  76500
          tcatctgctg gaaatgtcca cgatggattt aattttaaaa aacttttttc tttcccaatt  76560
          tagggaatac ccactctggt gtacagacac gactggaact atgaacatct ctttatggac  76620
          atcaagaaca aaatggcaca ggtgatcccg ataaacctga tcctgtgcac ggggctttct  76680
          gccttctcag tgtgtttccc tccgtgttag gcctactcca gccttgcccc gggtgtttgc  76740
          tgtgagccca cagtttctgc ggcctccctt acagagagca agcaagacag caaatcagca  76800
          agttttcttg tagagtaaaa gcagattgac atcttgtggg tttgattctt aggaatgatg  76860
          ttgatgcatg gccatgcctg ctgaagcggg aagtccatgg aaccgatttg ttcctgctct  76920
          ccgcatgcgg gtactgatag gtagacctgt gtgtctccat ggcctccagg aactgcctgc  76980
          acaccgtgcg cccaagtgtc agctgttaga gagttggccc cccgcatgtg gcttgggcag  77040
          tgaaggggct cggctctctt accaggtggt gagatgccag aaacccagcc cacagacatc  77100
          cctctcctgc ttttcatttc ccaggactcc ctccccagct cggtcattag tgccatcagt  77160
          ggacagctgc agtcctacag cgatgcctgt gaagtgctgt ctgtcgtaga agtcactctg  77220
          gggtttctga gcacagctgg tggggatcca aacatgcagc tgaatgtgta tactcaagac  77280
          atcctgcaaa tgggtgatca gacgattcac gtgttaaagg tgggtctcac accgaaaagg  77340
          aaatcagcac agcccctcac cctggtctcc tgcttcccgc gagggatagg agcattcagg  77400
          gagtgccact ctaggcgctc ctgaaaagga tggggagaca agaacaactg ctcacccagt  77460
          cagtccagca taaacaggac acaccaggga cagtagagac agacacgcgc tagaaatgcc  77520
          agcagtctag atagagccca aatgtgactg agtacatgag gcccctgcaa acagcgtgat  77580
          gtgagcgggc tgtgaggtgc cgcaggaggg aactggtaga taggacagag atggccttca  77640
          caaggaggga gatcacatta gtacagggca gaacgaagag aagaatgcct gtgtggagag  77700
          cactcaggct ccctggtgca cgacatgagt gggggtgtga gacctcagcc cccactcagg  77760
          aattctattc cttctgcagg ccttaaacag atgccagtta aaacacacca ttgccctctg  77820
          gcagttcctg tctgctcata agtctgaaca gctgctgcgg ctgcacaaag taagtctggt  77880
          ctcttcctct ctgctggaca gagggactgc gctcccttct ccctgcaggc tttaatgctt  77940
          catttgctct tccgtcgttt taggagccat ttggggaaat cagttcaagg tacaaagcgg  78000
          atctgagccc ggaaaatgct aagctcctca gcacattcct aaatcagact ggcctagacg  78060
          ccttcctgct agagctgcac gaaatgataa tcttgaaact aaagaacccc caaacccaaa  78120
          ccgaggagcg cttccgccct cagtggaggt atggatttgc acacctatgg ggcggggcag  78180
          acacaatgtt gtgctgtctc tcctgtgatc ttctatagac acaaaaatag ttcttttctt  78240
          accacagaat cccatttcct gctttttgtc attaccaggg cacctgagga ctggcttttt  78300
          ggttttaatc tctactgggt tttctttaag caattacaca agtgtttttc agacaagagt  78360
          cttgccctgt tacccaggct ggagtgcagt ggagtaatct caactcactg caaccttggc  78420
          tcactgcaac ctctgcctcc caggttcaag cgagtctcat gcctcagctt cccaaatagc  78480
          tgggactaca ggcgtgtacc accatgcctg gctaattttt gtatttttag tagagacaga  78540
          gtttcactgt gttggccagg ctggtctcga actcctggcc tgaaatgatc tgcccgcttt  78600
          ggcctctcaa agtgctagaa tgaaaaggcg tgagccacta cacccagcct aaaagtcata  78660
          tattctaatt ttataacaag tagactatgt caaagagagg tacattttaa atttgataga  78720
          aaaagctatc ctaggccggg tgtggaggct taccctgtaa tcccagcact ttgggaggcc  78780
          gaggtgggtg gatcacctga ggtcaggagt tcaagaccag cctggccaac tggtgaaact  78840
          ctgtttctac taaaaataca aaaattagcc aggcatggtg gtacacacct gcagtcccac  78900
          ctactcagga ggctgaggca ggagaattgc tttaacctgg gaggtggaga ttgcagtgag  78960
          ctgagatcgc accactgcac tccagcctgg gcaacagagg gagacttcat ctcaaaaaca  79020
          aacaaaaaaa agaatagaaa aagctatacc aatgtataaa gagtgtatga gaatactcaa  79080
          cattggatat tatccatctt ttacatagtt gccaatctaa aggccaaaat ggtatctcat  79140
          tttcagttgt atttccccat ttaccgtgag gctgaacatg ttttttatat ttatcaccca  79200
          tttgtatatc atcctctgaa ttgcctttat gttttatttt ttgagaccgt gtctcactcc  79260
          cacccaagct ggagtgcagt ggcgcaatct tggcttagtg caaccgctgc cttctgggtt  79320
          caatcgattc tcctgcctta gcctccctag tagctgggat tacaggtgcc aaccatcacg  79380
          cccagctaat tttttctatt ttagtacaga gacggggttt ctccacgtgg ccaggctggt  79440
          ctcgagctcc tgacctcaag tgattcacaa gctttggcca ccacacccag cctaaattac  79500
          ctcttcgtat ctttttcttt tgcgctttgt ctctgtaatg gttgtgagag ctctttgcat  79560
          agaacagggg ttcatcttct ctgccgtgtg ccacagtgct ctatttcagc ctttaatttt  79620
          atgaagtcaa atctgacaga attttcctat aaagggtctc tatacaaaaa cacttactag  79680
          gatcttcctt atcccaggat tataaactag cctttttttt tttttttttt tttttttttt  79740
          gagatggagt cttgctgtgt catccaggct agagtgcaat ggtgtcatct tagctcactg  79800
          caacctctgc ctcctgggtt caagcgattc tcctgcctca gcctcccgag tagctgggac  79860
          tacaggcatg cacctgcccg gctaattttt ttgtactttt agtagagacg ggtttcacca  79920
          tgttgaccag gctggtctcg atctcctgac ctcaagtgat ctgcccgtct cggcctccca  79980
          aagtgctagg attacaggcg tgagccactg cgcccggcct gtcctctctc ttcttgtgct  80040
          ttcacatact tgttttattc accagtttat gtttaggtgt aaagtaagga tttaacttga  80100
          tgttttcctg actagatcat caaactccag tcttcctcac caatatgttt cctatttgct  80160
          atcttcctcc attatgctat gtggcatata ccatatacat ttatgttctt tcaacttttt  80220
          caacaagtct ttactagcct gtgcttttca tgtagataaa aaagatccct ttcctagaga  80280
          atttccagtc tttgttaatg tgaaacatgt aatagaatac aaggtttttt gaatggtgag  80340
          gccttgttta tgcaaccctg taaataaaca tcaccttgct agagggccta aagtcatgtg  80400
          aaggggccag cacagggctt gctccgtggg cttctgtcgt gtttgtgtac tgcatgtggg  80460
          aagcagcagt caggcaccag agccttgaac ccaggatgct agtcccagtt caggagctca  80520
          ggtcattgac cttaaactgc tcctcaggat ttctgggttt tttttttttc tcgctctgtc  80580
          gcccaggctg gagtgcagtg gtgcaatctc ggctcactgc aagctccacc tcctgggttc  80640
          aagtgatttt cctgcctcag cctcccgagt agctgggatt acaggcaccc accgccatgc  80700
          ctggctaatt tttgtatttt tactagagac agggtttctc catgttggct aggctggtct  80760
          cgaactcctg acttcaagtg atccacctgc ctcagcctcc caaagtgcta ggattatagg  80820
          cgtgagccac tgcgcctggc ctaggatttt aagtcttaac gagcattttg gttctgctga  80880
          tgacaacggg aaaaagtaac atgaggggac tgattggtcc ccttatgtta tatgggagcc  80940
          tttttttttg agacaggatc tcactgtggc ccaggctgga gtgcagttgt gcaatctcag  81000
          ctcgctgtag cctccacctc ctggactcaa gtggtcctcc cacctcagcc tcctgagtag  81060
          cttcggacta taggcataca ccaccacgtg cccagctaat ttttgtattt ttgctagaga  81120
          cagggtttcg ccatgttgcc caggctggtc ttgaactcct gacctccact gacccaccca  81180
          cctcagcctc ccacagtgct gggcttacac acgtgagcca cacagtgctg ggcttacaca  81240
          cgtgagccac catgctgagg agactgtttt aaatgctctc ttctttggtt tttcagcctg  81300
          agagacactc tcgtaagtta catgcaaact aaagaaagtg aaattcttcc tgaaatggca  81360
          tctcagttcc cagaagagat actgctcgcc agctgtgtct cagtgtggaa aacagctgct  81420
          gtgctgaaat ggaatcgaga aatgagatag aattatttcc tcagctatct ttggatgact  81480
          ttggagagaa gactcctctc tcctcgtctg cggcgtggac ttgatcatgg actggtgcct  81540
          ttgcattcag aaggagagct gtcagcgtag caccgaattc aagaccaagg cgtgctacct  81600
          gagctgacag ctttttgaaa gccgagctgt ttctgaacca tgtacataca tgttctgaaa  81660
          ctttctcatc attttatgag tactgttcat tgagagatga caatgaagat tagatgaaat  81720
          tggaaataaa ccaacattgt ttacattcca ggagacttgt agctcagcca cacacgcagt  81780
          aatgacctgt gcccgttcgc ctctggcact gcccacccct cttttttttt ttcttctaat  81840
          tctgtactca caaaagagaa tctcattttc ttctttcttc cattccctta aattctgagt  81900
          actgtacata tatttctggg ttcccacgat gatgtgaaaa actaccagac tgttttttgt  81960
          cttctcacaa agacaagaaa aatcagggca ttttgtgagt gccttaagat caaactaaca  82020
          agatctgacc ctctcccctc acagtgagcc actgccccac ttcagagggt aagagccaaa  82080
          agcctcattg tgaaaggcac tggacttgga ccagggacac catcagggcc ttggttttct  82140
          cacgcataaa atggagagtg gattaatcgc caaagattct tctgatctga cattttgaaa  82200
          ttgtgagaga aactagatga ctgtaaactt ggtcacaggc ctggttctgg cagttctttg  82260
          cggacttttt tctagcatta tgccaaataa acatgcagtc tcagtgtgct ctcgcatgta  82320
          tgaatatcta gtcctttctg tggttctcag ccaagacata aaaactagga ctcagagcac  82380
          atacaaaacc agttatgttt cggaaagagg gaaaagagtc cccgagcccg gatcttgtgc  82440
          tgcttttctc actgacgtgt tgcctttttt ctttacaaaa tctgctttga tacttaggac  82500
          ctctctggac taatttctct tcctagacag ctcagcacag ctattgatat gttagaggca  82560
          gtatccttaa tattcattct aaatgagtta acgacttaac ttgaaattgg gcctaaggag  82620
          tgagaactac aaaaatacaa aatgcttgtc caggactcag ccatgcacac cttgagcagc  82680
          gccggcagga ggcacggaag gaactgtgct ccgttctcct cactgtcatg gtgccaccag  82740
          tgtctgatga agggcagagt gacccagact gcaggcagta actgacttca cacagtccct  82800
          ggcatttagt catctgtgat tgttttatca ctctggactg tgcagagcca cctgccaccg  82860
          agatctgcat tccgactgcc tatgaacggg tgtgggggcc gggggctggc ttgctgaagt  82920
          cttcaacttg cactcggagc tcctttgata cctcagagct ggctgtcagg tggcagctca  82980
          cacccagact cactggccac acctcagcag ggggggagtc gagtgtcagt ctctttctgt  83040
          gaaggctttt tttttccttt ggcctgggaa tttttcccat ttttatgaag gggttttaaa  83100
          ttgtttcatt ttgtgtgctg tgcttcaaag ccttaactgt caaatcttgc attatcttgt  83160
          ttgtacagaa atatactggc ctagcagagg caaaaaaaaa aaaaatgaat tttattttac  83220
          ttgtcacacc tgtcttaata aactggagtt ttgctgctaa agaactcttc tctctggggg  83280
          cagagcttct atttatggca catagacatc agctaggctt ttgggaatcg tttgtgttct  83340
          ttgtggaaat gtcctttaga agcacccatg aagtagtgtg ttcagactgt gcacacagaa  83400
          aacaggctct gccttcacat gtgagacggt ggacttttcc tctggacaaa atgacagcat  83460
          cctggcgact ccacagtgga gctgagcgcc actccctgta gccgatctgg gactgaaacg  83520
          cttacacctc tgcctcagaa ggagtccccc atgccctgcc tgaaatgact tcactggaca  83580
          cagcggggct gcagctaacg gggtacaggt aggagctaac taacttcacc cctgagtcca  83640
          cttgcggggt aagagataaa cagtaaccct tccaggagcc cactgacgtt ggagtgctaa  83700
          aaatgcccct tcagggggaa aactgcattt tctcttccaa aaaggaaagg ttcttccagg  83760
          cgagaaacct gtggtctaga accacagcaa gaagaggagg catgctggcc tgcaccggaa  83820
          gactcacttt gtctgccctg cgccagcctc acctcaccct gcagttcccg tttccgccat  83880
          ggatgcctca tcaccaaccc tgaccttccc cctcccaacc ctttattcat cctcactccc  83940
          actcataccc gcctccctgg acagttccct gctgcagagt tctttctgct ttcagcccta  84000
          ccttggtggt gatttacctg aaaatcttca caactgatca ttatctcctt ctctttgaga  84060
          cctgactgaa aaaattaggt gtgcacacct gtaatcccag ctacctggga ggctgaggta  84120
          tgaggattgc ttgagcctgg gagtttgagg ctgcagtgag ctatgattgc accactgcac  84180
          tccaacctgg gtgacagagt gagaccctgt ctcaaaaaaa aataaaataa ggaccttatt  84240
          gtgtgtgcaa attatttgcc tttcatgaat agttatgaga ctttgtgcat gtgttaaccg  84300
          agacggccct gagctatttc agttactcct gtatgttcag gcaattccaa tttagaaaca  84360
          aacttccagt gataaatatt gggaagaaaa tgtcagctca gggccaagta ggtaaagcca  84420
          cccaagtcta gccatgcaca caggcactag tgtgctgaag gaaaacacct ctgatttgat  84480
          acataaagtg tgaaggttgc ataactgggg aggtggctgg agaaaacctg agcctcgagc  84540
          tgagtaacaa tccaagccat gattagcatt tatattgcat tctgcattat tctcatccta  84600
          tcacgttcat taagttcaac cattaccatt acgaatcccg tttccagctg gaaaaacaag  84660
          cgccaggaaa gtgcatttcc cccccacccc ccccccccaa ccagagcaac tttggtcaga  84720
          agtcacacct aatcaccctc tctgcaggat atgctgggga tagccctttt gaggaggtgg  84780
          gggtgtatgc gaaagcaacc tggggccaaa gcagggggaa gcaggagaga ctggaggggc  84840
          cctgggtcca gcaagtgctc caccaggctg cccctgctca ggtgctccac agcccataaa  84900
          aaacgccttc agccctgctg tgcttcccct cacacctaaa cttactataa gggtcctacc  84960
          ttccccagta ttccttcatg atcactgcta cctgtgccct gaagcgcaac agaacctcaa  85020
          cccagaggac agccacttcc tcagaaccca cgatctttgc cccatcgcca caggtccatg  85080
          agtgactcct aattaccaaa tccaagggct ccttcaccct gaccactctg gaacccaaca  85140
          aagctgacac acagcccagc ccagacaggc ctgaatgtgg gtcctggctc tcccatttgc  85200
          cagttctaca gccatgggca agtggctcga cctctctaag cttcagtttc ctcgtctgtg  85260
          aaatatctgt cagtgctctt aagggaggag accaccccac atattgtctt acgcccaatt  85320
          tctgcctcca aagagagaag taaaaactaa aaggcagaaa tgaaatccac aagcagacag  85380
          cctgcaccac accctgggcc tggtagttaa agatcgacgc ctgacctaat cagtgatgct  85440
          atctatagat tacagacatt atatagaaaa gcaccgtgaa aatccctgtc ctgttctgtt  85500
          ccgttctaat tacgggtgca tgcagccccc agtcacgtac cccctgcttg ctcaatcaat  85560
          cacgaccctc tcacgcagac cccttaagag ttgtgagccc ttaaaaggga caggaattgc  85620
          tcactcgggg agctcagttg ttggagacat gagtcttgcc gaagcgcccg gctgaataaa  85680
          gcccttcttt aactcgtgtc tgaggggttt tctctgcagc ttgtcctgct acatttcttg  85740
          gttccctgac caggaatcta ggtgattaat ggatggttga ggcagcccct cagacggctt  85800
          aggcctgccc tgtggagcat ccctgtggag gactccagcc agcttgagcg acatggatcc  85860
          tgagagcgct ctcaggcagg caattgcccc agtggaatgc ctggccagag cagtgtgtag  85920
          caggcccccg aggaggatca acgcagtggc tgaacaccgg gaaggaactg ccacttggag  85980
          tccagacatc tgaaacttgg taagactggt ctttggaact tgcccactcc atttgagggg  86040
          aagcgtggcc tgatcaccca cggcgtgcct gtactggcac tctggttttt gtttttgact  86100
          tgacttggat tgcttgatac tttggttttg gttttgacct gacttggata tcctgatact  86160
          ctgattttgg ttttgatttt ggtttggtgt aaactgtaaa agtgtgtgtg tgcccttttt  86220
          acctgttctt tgttttgtgg tatgcgtgta gggtgagcgt aatgttttgt cttgaagaag  86280
          catgggtcaa gcacaaagta agaccacccc actaggaact atgctgaaaa atttcaggaa  86340
          aggatttaag ggagactatg gagtactatg acaccaggaa aacttaaaac tttgtgtaag  86400
          atagactggc cagcattaga ggtaggttgg ccatcagagt gaagcctgga caggtccctt  86460
          gtttcaaagg tatggcacaa ggtaacctgt aagccagggt acccacacca gttcccgtac  86520
          acagacactt ggttacagct ggttttagac tccccacccg cccgccccaa cagtggttga  86580
          gagaacagca gcataagtgg ctggcagagg caaggaaaga ccagcagaga gagaaagagg  86640
          aagagacaga caaagaggga gtcagagaga gagagagaaa gagacagagg caaaaggaaa  86700
          gtcaaagaga aagagacaga aaatcaagag gaaaaaaaga aaaaaagaga tatatataca  86760
          agtagttaga aacaacaaca acactgtacc ctattccttt aaaagccaag ataaatttaa  86820
          aacctataat tgataattga aagtattctc tgtaaccctg taacactcca ataccacttt  86880
          gttgtcagtg taaacaaggg catatcccga aagcactgag gccttcccat caaaaatcct  86940
          taacccagta acccgtggat ggctcaaatg cattcaatct gtagctgcaa ctgctttgct  87000
          aacagaaaaa agtaaaaaaa taacttttac aggaaacctc attgtgagca cacctcacca  87060
          gttcagaagt agcctaagga aaaaaaaaaa aggatgattt aactttaact actgaaaatt  87120
          cccttaaccc agcaggtttc ctaacagggg atctaaatct taattaccgt acaaaggccc  87180
          taccatacct aggaggaact cccttcagga aaggatgatc tatggttcct cccaggtaat  87240
          taaaggaaaa aaaaaaagcc atctatacga attctaagtt aattttgaca aaacgaggtc  87300
          ttactaatag caaaggataa ttaaaatccc aagcttacaa ggttttcaac aaaagtaaag  87360
          tttgctaaaa gttaacagtg taacatgtat tatagtaatt tctgatcttg tggcctcaga  87420
          cagtctagtc cacagacata aaagaagttc gctttggaaa agaatggtta tcatcttcag  87480
          gaaaaaaaaa aagaaggggc agaatttaca taaaaagagt gttatatggt aaattcttgt  87540
          cctgaaataa attaactggt tgtttaaaga aagaaatgtt tgtaataagt cagaaagttg  87600
          aggcatgtcg aagaattgtc tgcgaaagtc gtgaaagaga aaaatgttat aaaaaattat  87660
          gcaagaaatg ttgtataatt taaaagtaac taggcctcct aaatgtaaaa ctattgaaag  87720
          aaaaaaaaaa cagtttatgt gcaagtgtca ggcctctgag cccaagctaa gccatcatat  87780
          ccccagggac ctgcacgtat acatccagat ggcctgaagc aactgaagat ccacaaagga  87840
          agtgaaaata gccttaactg atgacattcc accattgtga tttgtttctg ccccatccta  87900
          actgatcaat gtactttgta atctctccca cccttaagaa ggttcttcgt aattctttgt  87960
          aatcccaccc ttgagaatgt actttgtgag atccaccccc tgcctgcaaa acattgctcc  88020
          taactccacc gcctatccca aacctacaag aactaatgat aatcccacca cactttgctg  88080
          actctctttt tggactcagc ccgcctgcac ccaggtgaaa taaacagcct tgttgctcac  88140
          acaaagcctg tttggtggtc tcttcacacg gatgcgtgtg acgtgcgtga catttggtac  88200
          caaagatccg ggacgggagt actccttaca gagaccggtc ccctgtcctc atcctcactc  88260
          catgaggaga tccacgtaca acctcgggtt ctcagaccaa ccagcccaag gaacatctca  88320
          tgaatttcaa atcgggtaag tggtcttttc actctcttct ccagcctctc tcgctaccct  88380
          tcagtctccc tgtccttcca attccagttc tttttcctct ctagtagaga caaaggagac  88440
          atattttatc cgtggaccca aaactccggc gccagtcacg gactcggcaa gacagtcttc  88500
          ccctggtgtt taatgactgc agggacgcct gcctgattat tcacccacac tccactggtg  88560
          tctaatcact gtggggatgc ctgccttggt cattcaccca cattcccttg gtggcaagtc  88620
          aattgcgggg acaacctgct ttggctgctc acccacattg cagcccacgg ctgctcccta  88680
          ccccccttct ccgtgtctct acccttctct ttaaactggc ctccttcact gtgggcaacc  88740
          tttcaccctc cattcctcct tcttctccct tagcctgtgt tctcaagaac ttaaaacctc  88800
          ttcaactctc acttgaccta aaatctaagc atcttatttt cttctgcaac accgcttggc  88860
          cccagtacga actcgacaat ggttctaaat ggccagaaaa tggcactttt gatttctcca  88920
          tcctgcaaga cctagataat ttttgtcgaa aaatgggcaa atagtctgag gtgccttacg  88980
          tccaggcatt tttcagactt cgttccctcc ctagtctctg ttcccactgt gactcatccc  89040
          aaatcctcct cctttccctc ccgcctgtcc cttcagtccc aacctcgagc gttgctgagt  89100
          cttgtgaatc ttccttttct gctgacccat ctgacccctc acctcctccc caggctgctc  89160
          ctcctcagct cgctccccgc caggctgatc aggctccagc tcttcttcag cctctgctcc  89220
          ccaccctata acccttctat tacctccctc ccacacccgg tccggtttac agtttctttc  89280
          tgcgaccagc tctcccccat ctgcccaaca atttcctcat agagaggtgg ctggagctga  89340
          aggcatatgt cagggtacat gtgccttttt ctctatcaga cctttcccaa atcagccagc  89400
          gtttaggctc tttctcatca gaccccacta aatacataca ggaattccga tatctaactc  89460
          tgtcctacag tttaacctgg agtgactgaa atgtcatcct aacttctacc ctctccccag  89520
          ataaatggga aagagttttt tctctagccc aatctcacac tgacaaccac cggcttcacg  89580
          agccagacct ccaggagggc atcagagcag ttccccgaga agatccccag tggaactacc  89640
          aggcagattc cccaggtata gctacgcgag attacatggt ttcctgccta gttgaagggc  89700
          ttaaaaaggc agcttacaaa gctgttaatt atgacaaaca agaaactacc cgaggtgaag  89760
          atgaaaaccc agcccagttc atggcccact tggcagtaac ccttagacgc tttaccgccc  89820
          tagacccaga ggggccagga ggccgcctta ttcttaatat gcattttatc acccagtcag  89880
          ctcctgatgt tagaaaaaag attcaaaaac tggaatccag ccctcatacc ccacaacagg  89940
          aattaatcaa cctcaccttc aaggtgtaca ataataggag gtagccagac agcaacgcat  90000
          ttctgagtta cagctactcg cctctgctgt aagacagccc acaaccacgt ctccagcata  90060
          caagaacttc agaacatcca agccacagct cccaggggct ccttcaaaac atcctcgtgg  90120
          gccttgcttc aaatgccaaa agcctggcca ctgggccaag gaatgcccgc agcctgggat  90180
          tcctcctaag ctgtgccctg tctgtgcgcg cccccactgg aggtcggact gtccgactca  90240
          catcgccgct gctcctaaag cacctggagc ccaaacccaa cgttccttgg ccaactcctt  90300
          cccagatctc ctcggcttag tggctgaaga ctgacgctgc ccatcgcctc gggagcccct  90360
          ggaccatcac agacactttg ggtaactctt acagtggagg ataagtctgt ccctttctta  90420
          atcaatacag aggctaccca ctccacatta accttttttt caagggcctg tttcccttgc  90480
          ctccgtaact gttgtgggta ttggcggcca ggcttctaaa cctcttaaat tccccaactc  90540
          tggtgccaac ttggacaaca ttcttttatg cacccctttt tagttatccc cacctgccca  90600
          gatcccttac tagattgaga cattttaact aaattatctg cttccctgac tattcctagc  90660
          ctacaaccac acctcattgc cacccttttc tccagttcaa agccgccttc acaccctccc  90720
          cttggatctc cccaccttaa tccacaagta taggacacct ctactcccac cttggcaacc  90780
          aatcatgcac cccttaccat cccattaaaa cctaatcact cttaccccac tcaatgccaa  90840
          tatcccatcc cacagcacac tttaaaagga ttaaagcctg ttatcactcg cctgttatag  90900
          catggccttt taaaacccat aaacactcct tataattccc ccattttacc tgttccaaaa  90960
          actggacaag ccttacaggt taatttcaga atctgcacct tatcaaccaa attgtcttgc  91020
          ctatccaccc tgtggcgcca aagccatata ctcttctatc ctcaatacct ccctccagaa  91080
          cccctctaca tatattatta tgtagatatg tacatatcta catatgtaca taatctacat  91140
          aacccattct gttctggatc tcaaacatgc tttctttact attcctttgc acccttcatc  91200
          ccagcctctc ttcattttca cttggactga cccggacacc catcaggctc agcaaattac  91260
          ctgggctgta ctgccacaag gcttcacgga cagccccccc cccccccgtt acttcagtca  91320
          agcccaaatt tcttcctcat cctttaccta tctcgactta attcttcatg aaaacacagt  91380
          gctctccctg ctgatcgtgt ctagctaatc tcccaaaccc cgaccccttc tacaaagcaa  91440
          cagctccttt ccttcctagg catggttaga tactccgcct ttggatacct agctttacca  91500
          tcctgactaa accatcatat aaactcacaa aagcaaaccc agctgacccc acagatccta  91560
          aatcctttcg ccactcctct ttccgttccc tgaaaacagc cctagaagct gctcccacac  91620
          tagctctccc taactcatcc caacactttt tcattacata cagccaaagt gcagggttgt  91680
          gcagtcagaa ttcttacaca agagccagga acggcccctg cagcccttct gtccaaacaa  91740
          cttgacctta ctgttttagg ctagccccca cattattcct gataccacac ctgacccccc  91800
          atgactgtat ctctctaatc cacctagcat ttactcaatt tccccatatt tccttctttc  91860
          ctgttcctca ccctgatcac acttggttta ttgatggcag ttccaccagg cctaatcgcc  91920
          actcaccagc aaaggcaggc tatgctatag taacttccac acctatcatt gaggctacca  91980
          ctctgccccc ctccactacc tctcagcaag ccaaactcat tgccttaact caagccctca  92040
          ctcttgcaga aggagtacgt gtcaatattt atactgactc tatgccttcc atagagtcag  92100
          catgcaccac catgctgtta tatgggcaga gagaggtttc ctcactatgt aagggtcctc  92160
          catcattaat gcctctttaa taaaaattct tctcaaggtc gctttacttc caaaggaatc  92220
          tggagtcatt tactgcaaga gccatcaaaa ggcatcagat cccatcattc agggcaacac  92280
          ttatgctgat aagttagcta aagaagcagc ttagttttcc aacttctgtc cctcacggcc  92340
          agtttttctc cttctcatcg gtcactccta cctactctcc cactgaaact tccacctatc  92400
          aatctcttcc cacacaatgt aaatggttct tagacaaagg aaaatatctc cttccagcct  92460
          cacaggccca ttctattcta tcatcatttc acaacctctt ccatgtaggt tacaagccgc  92520
          tagcctgtct cttagaacct ctcatttcct ttccatcgtg gaaatctatc ctcaaggaaa  92580
          tcacttctca gtgttccatc tgctattcta ctactcctca aggattgttc aggccccctc  92640
          cctccctaca catcaagcgc ggggatttgc ccctgcccag gaccggcaaa ttgactttac  92700
          tcacaggccc cgagtcagga aactaaaata cctcttggtc tggatagatg ctttcactgg  92760
          atgcgtagag gcctttccca cagggtctgg gaaggccacc gcagtcattt cttctcttct  92820
          gtcagacata attcctcggt ttggccttcc cacctctata cagtctgata acggaccggc  92880
          ctttattagt caaatcaccc aagcagtttc tcaggctctt ggtattcagt ggaaccttca  92940
          tatcccttac catctcaatc ttcaggaaag gtagaaggga ctaatggtct tttacagaca  93000
          cacctcacca agctcagcct ccagcttaaa aaggactgga cagtacttct acctcttgcc  93060
          cttctcagaa ttagagcctg tcctcaagaa gctacacggt acagtccatt taaactttta  93120
          tgtggacgca ctttcttgct cagccccaac ctcatcccag acaccagccc tctaggcaac  93180
          tatcttccag tctttcagca ggctagacag gaaattcgcc aggctgctaa tcttctcttg  93240
          cctactccag attcccagcc acatgaagac accctagctg gatggtcagt tcttgttaat  93300
          aatctgaccc ctcaaactct acaacctcga tggaccggac cctacttaaa catctatagt  93360
          acccccaacc accatctgcc tgcagaaccc tccccactgg gttcaccgtt ccagaataaa  93420
          gctgtgtccg tcagacagcc agtccgatat ctcctcttcc tcctggaagt cgcaagtact  93480
          ctcccctact tcccttaaac tcactcgcat ttctgaagaa caataaccct tatgagccta  93540
          atacatccct tcattctatt aggtctatcc atccttaccc tactcttcgc aacagggctt  93600
          tacgcagtca cccccactac ttggactgtg ccccaaaaac ctgtcatccc tactatcttc  93660
          tgtctagtca tactcctatt caccattctc aactactcat aaatgacctg ctcttgttta  93720
          cactgccagt ttacattgtt tctccaagac atcacagctg atatctcctg gtgatatccc  93780
          caaaccgcca ctcttgactc ctgcttggag tggatagatg atctttggtg gcagggcacc  93840
          ctccaacact tccaccctga tgaagttcta ttctttactt ttatattcac tcttattctc  93900
          attcccattc ttatgccact ctctacctct ccccagttac ctccagcata ctatcaatct  93960
          cacccactct ctcctcactg cctccaatcc ttttctagca aagaattgtt ggctacgcgt  94020
          ttccctttcc tcctgctttt acacagccat ccctgctcta caggctgact gggctacctc  94080
          tcccgtctcc ctgcaactca gaacctcctt taataaccct catctttacc cgcctgagga  94140
          acttctttat tttctagaca gatttggtga gaactcccca gacatttcac accaacgagc  94200
          tgccacactt ctccgcatct acttacggca tctttctcct tatgtcaatt ccactcctcc  94260
          catatttgga ccccaaccac acaaacaact atccctgttg ccgtttcttt atgcatctcc  94320
          cgacaacagc ctgctggaat ccctttaggc aaccttccac cgtccaaatg ttcctttact  94380
          ctttgtctcc agaacccagc cacacacatt accaaacaga tgggagcatt ccaacttcgc  94440
          attactgaca agccctctat cattattgac aaactaaaaa acattggcag tcactattgt  94500
          ttaggaagac acctaccctg catctcaccc catccttggc taccaccctc ccctgctcgt  94560
          ctgaatctcc tcctagcccc tcctcttgct tgcttatacc ctgccccatg aatagcagcg  94620
          aaaggttact tgtagacact atgcgctttc tcatacacca tgaaaaccaa acccctccct  94680
          ctacgcagtt gcaccatcaa tccccattac aacctctaac ggctgctgcc cttgctggat  94740
          cgctaggatt ctggatgcag gattcctctt tcagtacacc ctctcacctt ttcactttac  94800
          atttccagtt ctgcctgaca caaggtctct tctttttatg tggctcttcc acctacatgt  94860
          gcctacctgc caaatggatg ggcacatgta ctctagtctt ccttacctcc aaaatccagt  94920
          ttgcagatgg gaacgaacaa ctgcctgtcc ccctcatgac atcaacacaa caaaaaagag  94980
          tcatcccact aatcccttta cttattggtc taggactttc tgcctccagt attgcacttg  95040
          gaactggaat agcaggcatc tcaacctctg tcacaacagt ccgcagcctc tctaatgact  95100
          tctctgctag cactacagat agatcacaaa ctttatctgt tctccaagcc caggttaact  95160
          ctttagctgc agttgtcctc cagaacggcc aaggccgcga tttactcact gctgaaaaag  95220
          gaggactctg tatattttta aatgaagagt gttgttttta cctaaatcaa tctggcctgc  95280
          tatatgacaa cataaaaaaa ctcaaggata gagcccaaaa gctcgccaac caagcaaaca  95340
          ataacattga acccccttgg acactctcta attggacgtc ctgggtactc ccaattctta  95400
          gtcctttaat acctattttt ctccttcttt tattcggacc ttgtgtcttt cgtttagttt  95460
          ctcaattcat ataaaaccgc atccaggcca tcatcagtaa ttctatatga caaatgctcc  95520
          ttctaacaac cccaaaatct ttcttcagtt gaatctctcc cactgtaggt tcccacaccg  95580
          cccctgatcc cgctcgaagc agccttgaga aacatcgccc attatctctc cataccaccc  95640
          ccaaaatttg tcactgctcc aacacttcac cactattttg ttttgctttt cttattaata  95700
          taagaagaca ggaatgtcag ccctctgagc ccaagctaag ccatcatatc ccgtgacctg  95760
          catatacatc cagatggcct gaagcaactg aagatccaca aaggaagtga aaatagcctt  95820
          aactgatgac attccaccat tgtgatttgt ttctgcccca tcctaactga tcaatgtact  95880
          ttgtaatctc tcccaccctt aagaaggttc tttgtaattc tccccaccct tgagagtgta  95940
          ctttgtgaga tccaccccct gccggcaaaa cattgctcct aacccaaccg cctaccccaa  96000
          acctgtaaga actaatgata atccaccacc ctttgctgac tcttttcaga atcagcccgc  96060
          ctgcacccag gtgaaataaa cagccttgtt gctcacacaa agcctgtttg gtgggctttt  96120
          cacacggagg cgctaacaca aggtgtataa gaaaagtaaa tatacctttg gtaaaaggat  96180
          tataagaagg cataagaatg taaattttta cctagattaa aaggttaaaa aaattgtttt  96240
          gaaggtttaa gcaagtttta aaacattaat tataaaaaaa ttctgtgtgt aaacgtatta  96300
          gctaaagtta aaggggtatc atccagtttt tctgtgaact ggacattaaa gtaaaaacac  96360
          aatgggtttt tcttaaagca ctaacttgct ctttaacaaa gattataaaa ggttaaaaag  96420
          agtctataaa aatcttacct tacggtctga cattaaaaat tgaataaata tgtatacaaa  96480
          gttttattaa aactaagttt aacattaata gcacactaat ataaaggtga aatttagctt  96540
          atctggtata aaaatcatac agaaagcatt attaaatata aaacagtgtt tggctttctt  96600
          tggtccaaaa actaataaaa ataggtggta aaggaaattt ctcagtaaaa aggcaccaaa  96660
          gcctataaag tccactcttg atgtccccac atttgaaaca aaaaatcaat ttcttagaaa  96720
          ttatatactt ggtttgtctt ccactttcct ttccctcaaa actaaaagcc ttttagcaca  96780
          ggtgccagcc ctagaatttc cagtaaacca gcaccagcct gaagatcacc ttcttatcaa  96840
          agggaggaaa gaaaacaaat ttttcaaagg aaaagttttt cttatcaaag gaaagaaaga  96900
          aaacaaaggg aggaaagaaa acaagccagc ctaggaagga cccgaccttg tgctgctaac  96960
          caccgagact gctgtcccta cagtggaaaa gggatggact catcacaccc gagtcaaagc  97020
          tccaccccct ccggagtcgt gggccccagt ccaaggggaa aaccctacca aactaaagct  97080
          aagaaatatt taactctttt atctattcta ttactctttc ttctttcctc gctctattgc  97140
          tgaccatctg gttattaaca caaccaaatc aatttcacct caaactattg catttaatgc  97200
          ttgtcttgtt ataccctgtg gggacttgcc aagtcgaaga cagctctcta cttcagaaaa  97260
          gtacttctgt ccctcctgac tctcctcaga ctgggcatta gtaaattagg accatttaat  97320
          ccgggggaat ttcaataaag actccagtgt caaccaggag tcttgctccc caatgtagag  97380
          cttttatgcc gtagttggtc caacattctg tggaccacta aagagcaaga atggactgcc  97440
          ccaaccagtt tttgtaattt cccaaaatca tacattcatt ttactagaag ttcatattag  97500
          ttaaagactt aaaacaaact ttggcaatta agacagcata ccaagatgca aatgcctggt  97560
          tgaaatggat caaatattcc atccgcacgt taaacaaaag caactgttac gcttgtgcac  97620
          atggcaggcc agaggtcctg attgtcccct ttccactaag gtggtcctcc agtcgaccag  97680
          gtgtggctgc atggtagctc ttctccagga ttctacagcc tggagtaata agttgtgcca  97740
          agctctctct gctgtatccg aaagtctggc gccttgcggg tcagcccccg agggccatcg  97800
          agccgccgtc tcccaatact aagttcactt cgtgtctctc atgacaggga ggaaacttag  97860
          cattccttgg aaacctgaag ggatgcagtg agcttaaaaa ttttcaagag cctatcaatc  97920
          agccagccct tgttcatccc tgagtggatg tgagcggatg tgtggtggta ttgtggtgga  97980
          cctttactgg gcactctgcc gaataactgg agtggcgctt gtactttagt ccgattggct  98040
          atccctttca ccctggcatt ccatcaacca gagggaggaa aaataagaca tcgtaaagca  98100
          agagaagccc cttatgggtc tttcgactct catttccatt tagacgcaat tggagtccca  98160
          cggggaatac tagatcaatt taaaacttga aatcaaatag cggcaggatt tgagtcaata  98220
          ttttggtaga tgacagttaa taaaaatgta aattggataa actacatcta ttacaacaaa  98280
          cagcaacaag cttttcatga gttaaaagaa aaacgtaggc cccagccctg gggctatcag  98340
          acctgacaaa accctttaca ccctatgtgt cagaaagaga aaaaatgcag ttggagtttt  98400
          aacccagact gtgggaccct ggctaaggcc agtggcctat ctctcaaaac aactagacgg  98460
          ggtttccaaa gcctggcccc cgtgtctaag ggccctggca gcaacggccc tgttagcaca  98520
          agaagcagat aaactaaccc ttggacaaaa cctgaatata aaggcccccc acgctgtggt  98580
          aactttaatg actaccaaag gtcatcactg gttaacaaat gctagattaa ccaagtacca  98640
          aagcttgcta cgtgaaaatc cccacataac cactgcagtt tgcaacacgc taaaccccgc  98700
          caccttgctc ctgatatgag agagcccagt tgaacataac tgtgtagagg tgttggactc  98760
          agtttattct agcaggcgca acctccgaga ccatccttga acatcagtag gctgtgagtg  98820
          gtacgtggac ggaagcagct tcgccagccc ctgcaaagtg actctgagga agacgacaag  98880
          ccctgctcca gtcacaactg gaagctgact ggtccacaca cggccgaagc atgagaaaac  98940
          tcatcgtggg actcattttc cttaaaattt ggacttgtac agtaaggact tcaactgacc  99000
          ttcctcagac tgaggactgt tcccagtgta tacatcaagt cactgaggta ggacaaaaag  99060
          ttgccacagt cctattattt tatgattatt gtaagtgtac caggactcta aaaaaaaaaa  99120
          aagtttgtat aatgctattc tatgcaaggt atgtagccca agaaatgacc aacctgatgt  99180
          gtgttatgac ctgagtctcc catgaccaca gcttttgaaa taagattaag gactgaggac  99240
          tggtagggac tcataaacga tacgagtaaa gtgttagcca aaatgaaaga aaaaggggtg  99300
          cccaaacaag tcactttaaa gtttgatgcc tgtgctgtca ttaatagtaa taagttaaaa  99360
          atagaatgtg gttcccttaa ttagaaaaga ggccatatga caaaaaataa gtacatttgt  99420
          cataaattaa aactgtgtgg aaataaatgt aaatactggt cttgtgtcat ttaggctact  99480
          taaataaaaa ataaaaagga tcctgtccac cttcaaaaag gaaaaagtgg cccttcctgt  99540
          accagtggtc agtgtaaccc cttagaacta gtaataacca acccccttga tcctcgctgg  99600
          aaaaaagggg agcatgtaac cctaggaatc aatggggctg aactggatcc ttgagtaaat  99660
          atcatggttt gaggagaaat ttataaacgc tctcctgaga cagtatttca aaccttctat  99720
          gatcaactga atgtgcctgc accagaaatt ccaggaaaaa caagacattt gtttttgcaa  99780
          ttagccgagc atgtggccca gtctctcaat gtcacttcat gttatgtgtg tggacgaact  99840
          gtaatgggag atcaatggcc acgggaagcc cgagaattag tacctacaga cccagttcct  99900
          gatgaattcc cggctcaaaa gaatcaccct gataacttct gggtcctaaa agcctcaatc  99960
          attagacaat actgtatata gcaagagtgg ggaaggactt cacctttcct gtgggaagac 100020
          tcagctgctt aggcaaaaac tgtataatac tactacaaaa acagccacct agtggagttc 100080
          aaaccacact aagaaaaatc catttagtaa attcccaaag ttgcaaactg tgtgaaccca 100140
          cccggagtcc cacagggact ggacagcccc cactggatta tactggatat gtaggcatag 100200
          agtttacacc aaattacccg accagtgggc aggtagtcat gttattggca ctattaaacc 100260
          atctttcttc ctactgccca taaagacagg cgaactcctg ggcttccctg tctgtgcttc 100320
          ccgcaaaaag agaagcatag ctataaaaaa ttcaaaagat aatacatggc cccctgaaag 100380
          aatcatacaa tattatgggc ctggtactta ggcacaagat ggctcctagg gatacccgac 100440
          ccccatttac atgctcaacc gaatcatacg gttacaagct gtcttagaaa taatcactaa 100500
          taagaccggc agagccttga ctattctggc ctggcaagaa actcagatga gaaatgctat 100560
          ctatcaaaat agattggctc tcgactactt gctagcagct gaaggagagg tctgtaaaaa 100620
          atttaacctt actaattgct gtctacacat agatgatcga gggcaattag ttgaagacac 100680
          agttagaaat atgacaaaac tggcacatgt gcccgtgcaa gtgtggcatg gatttggtcc 100740
          tggggccatg tttggaaaat ggttcccagc actaaaaaga tttaaaactc ttatattagg 100800
          agttacaata gcaatagaaa cctgcgttct gctcccttgt ttgctaccca tacttcttca 100860
          aatgataaaa agcttcatcg ctaccttagt tcaccaaaat gcttcagcac aactgtacta 100920
          tatgaatcac tatcgatctg tcttgcaaga aaacataggt agtaaaaata aaagtgacaa 100980
          ctcccactac tgagtgagat tctcagagag ggagaataag ggagaccacc cctcatattg 101040
          ttttacgccc aatttctgcc tccaaagaga gaagtaaaaa ctaaaaggca gaaatgaaat 101100
          ccacaagcag acagcctgca ccacaccctg ggcctggtag ttaaagatcg acgcctgacc 101160
          taatcagtga tgctatctat agattacaga cgttatatag aaaagcaccg tgaaaatccc 101220
          tgtcctgttc tgttccgttc taattacggg tgcatgcagc ccccagtcac gtaccccctg 101280
          cttgctcaat caatcacgac cctctcacgc agacccctga agagttgtga gcccttaaaa 101340
          gggacaggaa ttgctcactc ggggagctcg gttgttggag acgtgagtct tgccgaagct 101400
          cccagctgaa taaagccctt ctttaactcg gtgtctgagg ggttttgtct gcggcttgtc 101460
          ctgctacact ctggtgggaa agacaccgca gcaggggagc agggtgcgca gggtgcagtg 101520
          ggtgacgctc attcgctgaa aactgaccct gctttcaaag ccttgtcagt tcccaaagct 101580
          gtatgaagcc tttcctgagc ctcaacctct agagtctaat ttcatcctct gtattttccc 101640
          ctttgttagt ccaaactgcg tcattttgta agcccctttc cattttgtag accttggtca 101700
          aagtgaaaca ttccacgggg gttcgagcca tgagaaacag cctgcctctt aacatattct 101760
          gctgggacaa agcgccagga acaccacatt ctgccggaac cacctcatcc tgggaacacg 101820
          ttaacatctt cccggacagc aagccatact gcctagatcc ctcctgccca ggcctatgag 101880
          taccccagcc tgtaatcgct ggtgggctct ggcattaagc tggcccccga caggtgtttg 101940
          caatacacct gtgttgctgt agagccgccc gcgcgccggc aatctcactg tgcgtcattc 102000
          tttaaccttc accttccctt caaaacctaa cacccttgac gtttatattc aggctattat 102060
          atatacatac acacatacac ccttctgaat cctcccagga gaatataaaa ccatgggtta 102120
          aactgctaca cttcagcttc agtggctgcc tttcagtgct tcaaatacac caacctcttt 102180
          cccaccccgg gacctgcacg agaaagctgc tccactcacc cgccgtgctc tttcactcac 102240
          ccttcaggtg tcttcaatat cgcctctcag gcctttccca accaccggtt taaagtcggc 102300
          tccccacaaa taaatacata ttctccctca cagtacttcg cacaacacct ggcacagcga 102360
          gagcactgaa ccaacactca ttcaatgagg aacacgaggt aagaaccaag accccccaag 102420
          gtcgccgtac tttgtctggt aggagaagct ttctgcccag caaggtccga cccagatgaa 102480
          accccgtcca agtctgcagc acccccgtga gtccagcccg ctaaactgtg aagaatttaa 102540
          atacacgaca cctgccctca aaagcttgag ggcacccctg agctgccatc gaggtggggg 102600
          cgtcaacgac aggcgctcag taagtgctcc tgaggcaact gccgggctgt cctggacctg 102660
          gtgaatcctt tcggggttca gcaaaggcgg acgctgaccg ggccaaggag tgggacctgc 102720
          agtgctggac cacccttttc caagcgcaga agtgccgtgc ccgccggctc tcaacagggc 102780
          aagaggcccc tctcgccgtg cagagcgcag cgcttgcggc ggggacagca gaggcgggac 102840
          gggcgtcacg gagttcccgg gtcctcgcgc ggtcacttac ctggcctcag ctatccgctg 102900
          aaaaaggggc ggacggcctc ccgggatccg agccgatatc gcgcgcggcg ccgcggggca 102960
          acctgaagcc gtgtgcgtgc gtgtgcgttc acgcaggggc tcacccagcg gccacgggct 103020
          tctgaagacc cgggtgggaa gtgcggcccg ggaaagcgca agcgtctcca tggcaacgag 103080
          ggcggacggc gtcagagcga gtcgcttccg gaagtgacgt gcggaagggg tgcccgggac 103140
          gaagccatgg ccctggaggc ggcgggaggg ccgccggagg aaacgctgtc actgtggaaa 103200
          cggtaatgct gtcaggcgac gcgcaggagg cgggggccga ggccgggcgg cccttcgcgg 103260
          accctccgag ctcatagtct tcaggctgtg gaatcggagc tgccaccgcc cgagactcca 103320
          aagcaaagcc cagtttccgg cgcggaagcg gagggatctc aggaattgta gtccgcgggg 103380
          tgggcgcggt tctcgcttcc ggccagtttg tctggcctgc gcttgcgcgg gtctccgccg 103440
          cctgggctcc tagggactgt ggcctcggcg gtatgtccct tgctttccct tgaagcggga 103500
          gaagacccgg cagaggcgct ctgtccgctg cagccgcgcg ggtggaggag gcagagtctg 103560
          aggtgtgacc ccgaccaagt ttgacgcttc tgtcctccta gggagcaagc tcggctgaag 103620
          gcccacgtcg tagaccggga caccgaggcg tggcagcgag accccgcctt ctcgggtctg 103680
          cagagggtcg ggggcgttga cgtgtccttc gtgaaagggg acagtgtccg cgcttgtgct 103740
          tccctggtgg tgctcagctt ccctgagctc gaggtaacct gggaggacgc cgagctcgag 103800
          gcgggcccct cggtgggctc gggcgtgcgg tctccgggac agggagcagt gcaagcgtag 103860
          aacccggctt ctcgttttgt aggatgtcat taatagtctg gggagttggc cgggcgcggt 103920
          ggctcacgcc tgcaatccca gcactttggg aggctgaggc gggggaatca cctgaggtcg 103980
          ggagttcgag accagcctga ccaacatgga gaaacccggt ctctactaaa aatacaaaat 104040
          tagacgggtg tggtggcata tacctgtaat cccagctact cggaaggctg aggcgggaga 104100
          atcgcttgaa cccgggaggc ggaggttgcg gtgagccaac atcacgccat tgcactccag 104160
          cctcggcaac aagagcgaaa ctccatctca aaaaaaaaaa aaaaaaaaaa aagtctgggg 104220
          agtcttggaa gggaaaaaaa ggcaaaaatt aagggaattc tgtgactatt aagaatcagc 104280
          tcatgagctt tatcttcaag tctgattgtt atcttgggtt cttcatctca gtgacctgtc 104340
          caccacgctc ccagttgccc aagctggaga tctgcatcct cctgggcccc tccgttcctc 104400
          tcgcgtccag ttgcacacta gctcgctttt attctgcctc ttaaatgtcg ctggaatctg 104460
          tccccttgtc tgtttcccct ctgctccttc cctggctgtg ccaccatcac tcctgtgggt 104520
          tcctgagcag cattttcatg ggtgccctgg ctcaaatgtt cctcctcagt ggtttctttt 104580
          ccatactgcc agcagaccaa ttttcctaaa aagcaagtat tttcctcaaa agcaacaagt 104640
          cccctccctc cctccctccc tcccttcctt ccttccttcc ttcctccctt ccttcctctc 104700
          tctgtctctc tttccttcct ttccccttcc cccactctgt gcccaggctg aagtgcagtg 104760
          gcataatctt ggctcactgt caagatctga tctcaacctc ctggactcaa gtgatcctcc 104820
          caccttagcc tgagtagcta ggaccacagg tgtgagccac tacacccggc ttattttttt 104880
          attttttgta gagacaggat ctcactatgt tgcccagggt ggtctccagc tcctgggctc 104940
          aagggatcct cctaccttgg cctccccaag tgctgagatt acaggtggga accaccacac 105000
          ccagcccaca agtcctctta gaacattgaa gtgcccttct catgacctca tggtgaataa 105060
          agttcactct ggttggcatg gcttcaaggc ccgtcatgac ctgtcccctg cgtaatttaa 105120
          tatgacgctg gaggctcagc cctcaccact attctcagtt cttcccacct cctacagccc 105180
          actgtgagtc cctcacgtgt ttgctacgct gtatttggcg gcctgacctt tgcagtaatg 105240
          tttcttctgg aagggtttcc atctggctaa ctactactca tctctttggg ctcagtttag 105300
          acatgacgtc ctccactaag ctccctctca tcccacaaga cgaggacttg tccctcagca 105360
          ccatgtctta gtccgtttgg gctgctgtaa tagaatacct tagactgggt ggcctaccca 105420
          cagcaggaat ttatttctca cagttctgga ggctggaggc tcaagatcag ggtgccagcg 105480
          caatcaggtt gtggtgacgg cgctctttca ggttgcacag ggccagcttc ttaaccgtgt 105540
          tctcacatgg tgatccactc acctccctag aggccccacc tcgtaatacc atcacctatg 105600
          ggttataatt tcaacatagg aatttgggga ggacaccagc atttagaccg tagcaaccct 105660
          ctgcttcctc ttgtcttgct gggatggaac tggcctgtct tccctactgg aatataaact 105720
          ccatgatggt agaaaccatg ttgctttgcc caccatggat agcatgagga agacgctgga 105780
          ctcttccttc aagagatacg tgtgtgaatg gacagtgggc tcatgattca cataagagtc 105840
          aacagctccg gaagcctctt ggcgtcactc gcattgctcc tctgctgact cccgaaggtg 105900
          acaaacgtct tcctgcttcc atggctttgt gctttacttg ggaggccctt ttcagtccaa 105960
          atcaagcaaa aatgtactga gtgcctactg tgtgctaaga ttgggatatt cagcagcccc 106020
          tactctaaga ggtcccctgg ccattgtgta ggctagcata gggagtgggg acacagtctt 106080
          agggtcctga ctactcatgc tcacacccaa ctctgccact ccccactttg ccctctaggc 106140
          ctctgtctcc ttttttctga cttgaggatg atagtggtat taatatccag ctcacagaat 106200
          tgtgatgagc agtacatgaa atgcatggaa agcagttaac acagcattcc cttccccctc 106260
          caacttctcc tggctgcaaa ttaatcacct catctgcatc ctgggcctct tttgaatgca 106320
          catgctgtta gagcgcttct cacattgtat taaagttagt catttatgat tccatttttc 106380
          ccactgactg taggttctca agagtagggt gtaccatatt tcttttacaa ccccagcacc 106440
          aagcaaagca cctgctactt cgtcggtatt cattgttccg gctatgaaag cttagactag 106500
          gaaaggatct tggaacagtc tggtccactg gttcctgaat gcccgaccgt ggacctgcag 106560
          gagcagaatc acccagaagt gtgttgagaa acagattccg taggcacatc cacagagaca 106620
          gaaagtggat ccttgggcct tggagttggg gtgggatgga tgggaagtga ctgctgatga 106680
          ggatgaggtt tatttagggg ttaaggaaaa tgttctaaag ttagattgta gtgatattgc 106740
          acaactctgt aaataccaaa accatcgcat tatatgtttt aaacaagtga actttatggt 106800
          atgttaattg tatctcagta aacctgttag gaaaaaaaac aggccgggcg cagtggttca 106860
          tgcctgtaat cccagcactt tgggaggctg aggcggctgg atcacgaggt caggcgatcg 106920
          agaccatcct ggctaacacg gtgaaaccct gtgtctacta aaaatacaaa aaaaatcagc 106980
          cgggcatggt ggcgggcacc tgtagtccca gctactcggg aggctgaggc aggagaatgg 107040
          cgtgaacctg ggaggcggag cttgcagtga gccgagatcg cgtcagtgca ctccagcctg 107100
          agcaacagag caggactctg tcaaaaaaaa aaaaaaaaaa acagattcca gagccctacc 107160
          ccacttactg ggggaaaaac tctcccagag tatagcataa gaatctgctt tttaaaataa 107220
          gctttcctgt gattctgaag cagagctggg ctggagaacc actggcctgc ttttcccacc 107280
          gtgaagaaca ctgtccttag catccctgac aaacgatggc ggagcccgtt ctgtgccaga 107340
          tgctgagcca tggctggtgt gtgctgctcc gcaggcctct ggcggagccc attccatgcc 107400
          agatgctgag cgatggctgg tgtgtgctgc tccacaggcc tggtggagcc tgttgtgtgc 107460
          tggacgctga gcaatggcta gtgtgttctg ctccgcaggg agctgactcc tacttgtctg 107520
          tgactcccat cgatcagttc tgccttcagg tagcaaaaca gaacggatct tccctgcctt 107580
          ctgcttgtca gcccttctgc tgctggaaac agctgcctgc tccttgacca cactgtccca 107640
          agaggctgcg atgacgtcca gcttcttcac tggtcagtgg ccctctggtc atgccctccg 107700
          ttcacacaat ccatctttcc gtctgcactc agaatcaaat gcaggaactt ggatgtggtc 107760
          tacccaagtc cctagaccta actgtcaccc acgccatttc agtcggtgta gctggaaaca 107820
          ctggtagctt ttgaggggca ccaggtcact ggcttatgtt gagattgctg gtcatccaga 107880
          cctgccccct acgctaatca tacagtgatt tttcttttcc cagattttta atttgaaaat 107940
          gtacatacat ccccccaaat tggaaaagga tacgttggac acctgtattc cttctactta 108000
          ggttcagctg ttgctgctct ggaatattct ctctcgcgca catgcgctct ttgtgtgcgt 108060
          gtgtaccgta catcccagcg actgtgacag ctcagaagac atcagcaggc ctgtcctgag 108120
          aatgacattc tcctccacag ccacagtgtc attatcatac tgattacaca tcatagtcat 108180
          cccataatgt cacctgaatg ataacattat gggagagatt cagatgtaag cagccacgcc 108240
          cctcctgtgg gaactcaggc cacacttgaa ttccacatgt cactgtgcaa agtgactttt 108300
          actctgtggg gatgtcagtg atccagcctg ctggcttctc tgtgaaccca aattctgtta 108360
          tcagaatgga ccctccccac tttgggtcat gggcagattt gatcagtttc cccattgagt 108420
          cattgatgaa gatgttgtga gaatgatccc caaccctctg tgctaataca gagcactccg 108480
          tctgctttgg tgtgtttaat tattgatcca gccacaagtg aggagtggaa gttgtgattt 108540
          gaaagctgtc accaagagat ttgggggatt cagtaacaaa actgcaggaa ggtagacagg 108600
          tctgcagaat gtggacatag tgggaaacgt cttcacatta agggcagtgt gactaaggaa 108660
          aacacaaggt taggagactc aggcctgcca tgttgtgctc taaactgcag cctctgcctc 108720
          ctgggttcaa gcagttctcc tgcctcagcc tcccgagtag ctgggattac aggcatgcgc 108780
          caccacgccc agataatttt gtatttttag taaacacggg gtttctccat gttggtcagg 108840
          ctggtcttga actcccaacc tcaggtgatc gtccgcctcg gcctcccaaa gtgctgggat 108900
          tacaggcgtg agccaccacg cctggccaac actgtgtctt ctttaagcct ccaacaaccc 108960
          atggaggggt ggggtggggc atcggcttca atacacaaag gaggagacac caggaaagca 109020
          aggggcaggc agaggtgatg cagccagcag ccttagcctt gcttctgatg aagaccaggt 109080
          cctggggggc tcccgcggac ctgatcccag ggaatcctcc tatggaccag gtcccggagg 109140
          ctcctcctat ggactagatt ccagggaatc cttctacagt ctaggcttca ggggctcatc 109200
          ctatgaacta gatcccgggg aatcttccta tggaccgggt cccggggaat cctcatacag 109260
          accagatccc ggggaatcct cctatggacc aggtcctggg ggctcctcat acagaccaga 109320
          taccagggaa tcctcctatg gaccaggtcc caggggctcc tactatacac atcaggtctg 109380
          ggagttgggg ctcctccagt ggaccgggtc cggggtgggg gttctcatat ggaccgggtc 109440
          ccagggggct gctgctatgg accaggtccc ggtgggggcg gggtgggggt gctgttgcta 109500
          cagaccaggt cccgggggag ctgctgctac ggaccaggtc ctgggggggt ctgctcctat 109560
          ggaccaggtc ccgggggtac ctgcccacca ccaatttgca gggtacatct tctagttcct 109620
          tcttccaaac ccatcatctc ataggtgagg cagggaaggg gagccatgag ggtgacgtaa 109680
          gggagaggga aggatgaggg gggcagggca tggacggact ggggatggag caggtggccg 109740
          aaggctgtgc ttcccactga gctgcgtgcc tggtgtcagg tggtgtatga ggagagccgc 109800
          atggtcagcc tcacagcccc ctacgtgtcg ggcttcctgg ccttccgaga ggtgcccttc 109860
          ttgctggagc tggtgcagca gctgcgggag aaggagccgg gcctcatgcc ccaggcaggt 109920
          gtctcatccc taggacgaga gaaaggtccc tccttccccc tgggggaggg aaggctgctg 109980
          caggtcgcca ccaccacagt ggcagggaga gactcatgag cttcctggaa gagaggaatg 110040
          aggatttcta aaaagctgga ccccagagac agtgccccct tcttgcctca gggatggccc 110100
          tgtcctgagg gccgaggggc agctcagctg actgtgactc tccctgtggc tccataggtc 110160
          cttcttgtgg atggaaacgg ggtactccac caccgaggta atcctgctct tggaggtcca 110220
          gggagggcac tgtggggaag agcgggggga gagggcacct ctgtcgtccc ccacagaaaa 110280
          tgctgggccc tcggcctctg ccgccagccc cctccaatgg cttctttctc ggcgcaacgg 110340
          ggacgcgcag tgcgctcagc cccgcctccc ccaccgccgg taaaggactg tctactttcg 110400
          cttcacccct tacctctttc ctgtccgcca ctgccttctc tacagtgccc tgtgctggct 110460
          catctccagg tgccactatc cagttctgac ctgatcacca aaagatgtcc cagggcccgg 110520
          gctcagagtg gccttccctg ccagccgccc aacctgcatg gcccgtcagg ccccttgtcc 110580
          acaactagac aggtgtaccc aggcccccac tgatgccagg aaccttggcc tagggagcgt 110640
          ggctgaggga gatgggctct tttttttttg agacggagtc tcgctctgtc gcccaggctg 110700
          gagtgcagtg gcgcgatctc ggctcactgc aacctccgcc tcccgggttc atgccactct 110760
          cctgcctcag cctcctgagt agctgagact acaggtgccc atcaccacgc ccggctaatt 110820
          tttttgtatt tttaggagag acggggtttc acgtgttagc caggatggtc ttgatctcct 110880
          gacctcgtga tccgcctgcc tcggcctccc aaagtgctgg gatttcaggc gtgagccacc 110940
          gcgcccggcc tagggagatg ggctctttta ctgttacata cagagctgcg ggcggcgcag 111000
          cagcacccag agagggccca ggaggggtga cattgggcct tcctggccag caagtgtgac 111060
          tcggccctgg ctgctgccct cgcacatggg tgcagagcca aagggttgtc atgtgccgac 111120
          ccacatgctc gtgccagcgc tggcaggcca ccgtcgaggg aagaggaagc tgggaggtgc 111180
          aggaaatgac cggagagctg cagtatccca gcacgccagc gaggtgctga ccctggcact 111240
          gaccgtgtca gagagaagga ggcttcctcc acggccttgc acccaggaca tcgggcacag 111300
          ggggctttcg cccaggtctg cttgggactt agatctggtt tccccagccc tctgcctgtc 111360
          cacagacctc tgctcactta gggaagcttt tggtaagact ggcttgtcct gaatccctgt 111420
          gccaggcccc agccccacct ccccaacccc accctccttt ctctctggca ggctttgggg 111480
          tggcctgcca ccttggcgtc cttacagacc tgccgtgtgt tggggtggcc aagaaacttc 111540
          tgcaggtgga tgggctggag aacaacgccc tgcacaagga gaaggtgagg aggggcctgc 111600
          tgcaggccat gcccggcagc tcagtggcgg ggctgtggtg gccctgggca tgaggacact 111660
          tctggaccag cccttgcctg ctgacgctgc cctcctcatc cctggcttgt ggcctggagt 111720
          aagaaagacc tgctttcctc tgggtgctgc attgcctgtc tcagctgagg gcgctctgag 111780
          ctcctctcct gcctcctggg tgtgcctgcc tctctggtcc cccttgcctc tgagccaccg 111840
          tggcacacca agtagggcta agtcctccag ttactgggga caggacgggc ttccaggctg 111900
          tcccgggcgc acttggtgct ttccccaccc cgccttgccc cagcccctgt ctcctcccct 111960
          gcatgctcag gtaccacagc ctccaggccc ccctcccgcc aagacctgcc tggagctgcc 112020
          acccacactc ttcctacctc accttcccct gcatcttcct cctctgggac cccatgttgg 112080
          cactgggagt gagacactca caatggaggg agctgttgac acccccagct gtttcactgg 112140
          atggcagatt ctgagagcag agactgtgtc tctcattcct cctagctctc aggtgcctgc 112200
          atggagaagt tgcttaataa aaatctgttg agttgatggg gaccttagac ccactcaatg 112260
          agccagtcca ccgccgccag aaataccagc ctgttgagct gtgtcagatg tgcccaaagc 112320
          aggagagaag ccacaggaag gaagcgggct cagcacccat cactgggcag tggcggcacc 112380
          tgtgtggctg ccagcctggc acagcggccc tgggcagatt gttgcccttg ttctaagccc 112440
          catcatcagg tttgaacagg gtcttgtggg cagcaccctc agctcaggga caagaccact 112500
          tcaccgcctg cacgctcagt gtcgtctcag gtggtgtggc tttgcctggg ctgtggctca 112560
          cctccaagat cagtcccctt ccctttcctg gcccagtgac tgggttttaa aaataaagag 112620
          acctgggccg gttgcggtgg ctcactcctg taatcccagc actttgggag gccgaagtgg 112680
          gtggatcacg cgattaggag atcgagacca tcctggctag catggtgaaa ccccatctct 112740
          actaaaaata caaaaaatta gccgggcgtg gtggcacatg cctgtagtcc cagctactca 112800
          ggaggctgag gtgggagaat cgcttgaaca cgggaggcag aggttgcagt gagctgagat 112860
          cgcgccactg tacttcagcc tgggcaacag tgcgacactc cgtctcaaaa aatagagact 112920
          tgccttcagc ccttcaccaa gaagagaggg gtttttttcc ccatttttcc ctccattttc 112980
          cagatccgac tcctgcagac tcgaggagac tcattccctc tgctgggaga ctctgggact 113040
          gtcctgggaa tggtgagtag ctagggccct gagctcctcc aaagccccgg ggtaggggat 113100
          cctttgcagg cagacacagg tgcatgcaga cacgcgtgca ctcacacttg cccacatcaa 113160
          ccccccgcct gcccgtccat ccatcctcct gcctctgact gagtccaggg tgtgatgttt 113220
          gtgtttcttt cctccagccg tgctgaggga gcccaccctc ccccagggac aagcagcagg 113280
          aaggcgccct gagggtgggc aggccctggc ccctgagagc actgcccctt cagcttcccc 113340
          cttgccccca ggacattttg tcagagctcc agctgctgag gctgtcctga ccctggtccc 113400
          ggtggcccag cccacaggac agccctcgcc ttccttgtca caggccctga ggagccacga 113460
          ccgcagcacc aggcccctct acatctccgt gggccacagg atgagcctgg aggccgctgt 113520
          gcgcctgact tgctgctgct gcaggttccg gatcccagag cccgtgcgcc aggtgggtgt 113580
          gctggggatg cggggaggca gcacaggctc ctctgcttcc tgccacctgc tgttcagggc 113640
          tccccagcag ctcagctggg gtcagagtgc agtgacatga ggacgggggt tcctgggccg 113700
          aggacaggtc acagacatct tgctggagag cttgctgggc cctgcagtca ggacagtaga 113760
          ctggggggtg cagggctccc aagagttcat ccccaggccc tgcaccccat gcactcagcc 113820
          tcccagcctc tctgagcctc ctgcacccag atacaggcca gcttggagaa tcagtgatgt 113880
          tagctcaggt ggtgaggtgt cctgccagtt cccagccagc ccctcaggtc ccagagggag 113940
          cagctgaact tgagccagga ggctcctgca ggaaagctgt gcaggcccca gagacgccag 114000
          tctggggact tgggtatgcc cgccccagga cccagcacaa aactggtgtt cggtccccca 114060
          ggaagggtga gaactctgct gaagccatca gctcagctga gaaaggactc agcctgtggg 114120
          ccagggagag acagctggca cgagatgccc acagacagcc tcgataggac caggggacca 114180
          caagacacgg gtggatgctg tcccagagaa gcccacagag tgagggttca agaaaagtca 114240
          gtcttaggaa gagacccgct ggaggaaggg gaaggacagc cctgggcagg aaggagtttg 114300
          atgtgctcaa gaaatggggg gcccggaggg tggctcacgc ctgtaacccc aacactttgg 114360
          gagacagagg tgggaggatc acttgagccc aggagtttga gggcgcccta ggcaacatag 114420
          accccgtctc tacaaaaaaa acgtaaaaac aaattagcca agtgtggtgg tgcgtgcctg 114480
          tggtctctgc tacttaggag gctgaggcgg gaggatcacc tgagcccagg aggtcgaggc 114540
          tgtagtgtgc cctgattggg ccactgcact ccagcctggg tgacagagca agaccttatc 114600
          tcaaaaaaac tttaaaaaac aaaaactcag caggaaggtg tggccggagc cagatggcag 114660
          tgaagtacag agtgggtggg agcccgtgag catcttgggg tgcgccaggg tttcagacgt 114720
          cacccacagg gacttggatg gctgtgagtt ggcagcgggg cgcccgcaga ttggcctttt 114780
          taggtggccg ctgtgcgtgc tgtggaggct gtggacgcag gtctgcacaa gccatgctgc 114840
          ttccagcagc ccagcccctg agcctccctg gtgtctgccc cttccccatc ttaccccacc 114900
          gcttgccctg cagcctgccc tggggcagcc gcagcaccgg tggaaaaccc ccaggccacc 114960
          accttcgggc cggggccttc cggctgctgg cgcgcagtgt ggcctccagg gggcagcagc 115020
          agcccacata ccacaatggc cctcgccctg gggagctgtg ctcagtggtg gcgtctgaga 115080
          gcgggctcca cagccttgca gggctttgct cagggcacag gtgtgtggac tctcaagcct 115140
          gtgagctgtg tccccagccc ccaggaaaga ggcctttctt cctccattcc aactcagccg 115200
          tgtggtcttc cgagagagaa cccaagaaac tgtcccccag gccttcagcc acaggaactt 115260
          taggtcgtgc tgctgctgca gacagcacag ttcctggagc tcctgtacct ttttctgcct 115320
          cagcgcgccc cagagtagga cagtggccca tccttgcaag ggaggggaca cctggcctgt 115380
          gagtacctta agcatctaga aatagagcaa ggatctgtgc ctagcaccag caaagagcct 115440
          gccaaatcct gggcccaccc tccagaggaa ggaaagccgc aaccagttgg gatatgcagc 115500
          caccccgtac caggagcccg cagcttctta ctgttgggcg tgagccgagg atcgtgtcct 115560
          gcagggctgg ctctgtctct cggtccattt tcttcctgag ctcactcacc tctcaacagg 115620
          ttcacctcct gctctgttcc agaaggtcct gggagagcac agacggggtt agtgttggtc 115680
          tgctctctcc ctggctccgc gccgggccgt cttggtggcc ccatggtcac aggcgctgcg 115740
          gcgctcctgg ttgccaggtc caggctctcc tgccaggcca ggctgggccg ctccagggga 115800
          aggtgagagg tgctggcccc gcctaccgct gccccacttc ccccatgaat ggaagcagga 115860
          gcaggctggg ggattagccg ttgctttcca tgagtcgtgc agccctgaag ctaatctaag 115920
          ctcatctgag ctgggatcag ggggacttcc cagggccaga ccccccatgc ccccgggggt 115980
          tcccactcag acctgagccc tgttcagtgt ccctccctgc tagggtctgc ccccatccca 116040
          gcctgtggcc caccgccctc ttttatcttg gtgattctgg agacgggaca ggggttactg 116100
          ctgatctagt cagggagagg acagaccagc tgggctcaga gcccccagag aagcaagtgt 116160
          tagcagggaa gcctcggctt gcgcagagcc tacagggaag cacagactgg aaaccagtga 116220
          aggctgagca gctccaactg ccactggtgg ggaggagacc caggaccccc tcactcagcc 116280
          tgtccactca ccagctactc aggcccttca gggactgccc agctcggttt gagagctgcc 116340
          attgcggggc tttgacccca aagtcccagg catgcctgtc ccacactcgc tgacagggcc 116400
          gcggctcctg agcctgaaga actggctgtg acctgtgtgt cctgagtggg cttctgtggg 116460
          ggatggaggc attgccagca gcagctcctg gtgggaaact ggtctagaga ccagctcagc 116520
          acccagcagc acgtctgtct cccccaggct gacatctgct cccgagagca catccgcaag 116580
          tcgctgggac tccccgggcc acccacaccg aggtgagcac ccagggaggc tggggcacta 116640
          aaggggcatc tcacagacac ctgcatgggc tgtttccggt ggctcagcct ctccttgttg 116700
          caatattgtg gctcaggaca gacagtgcag ggccagggaa ggcaggggac acaggagagg 116760
          tcttcaaaga gggaggagag tggagtgggg tagactccta ttctcgtggg aactctccag 116820
          aaacaccact gcctccacgc aaagccctgg aactacggcc ctgtctggtc caagccctac 116880
          ctcccaatag ggctatcccc agccttcctc agtccactta gcctgtgagg taccaggacg 116940
          tgggctctgc agaaaaggcg tggcctcgga gtcagacatg atccagccct gcatagccag 117000
          ctgtggcgtt tgcactcttc gagcctcagc ttcctcatcg tcgggatagg ctctgtaatt 117060
          cttgtcccac tggttcttgt aagttagagt gacagtgtgc ctggcacagt caccgctaac 117120
          agtgcaaggc attgtcttaa aaccattgca gatggtttga tcctgctagc aaccttgatg 117180
          tgagacaagt actgtgaccc cactttacag atgaggaggc tgggacactg agtgttgata 117240
          aggagtaaag cagaattcag tctggctact tcctcttctc tcagtgtggg cagtttggat 117300
          tccaggccct gcatctgagc ctccaggctg agaggacacc cccactccct aggcaaagat 117360
          cgcaggaggc cccaggcctg ggattcgccc tgccctcgcc cacgattagt tactgaaggg 117420
          ctgcggttcc ttcgtgctca ttttccctct aagccagggg ctgttcccag gcctccctag 117480
          gctgctttga gaactgaggg agcaggtggc ggggaccccc caagctctcc cagagttgga 117540
          ggccggcccg cttgaatgca agctgcgtgt ctgagcagcg tgctctgccc tgccctctgc 117600
          cctgggctgt agcaggtcct gagtgtccag gccaagcgca gttcccagac cccatctggg 117660
          gtgtgagggg gtgtcaggta ggcgctagca tctgatgctg tccctttctc aatgtcatca 117720
          ccaggagccc gaaggcgcag aggccagtgg catgccccaa aggagactcc ggagagtcct 117780
          caggtgaggg ccagccccca caggaccaca gcccaggccc caggacagcc ccaaggccag 117840
          gctcccagga gcaggcgggc aaggactggc agtagggtgg aactgggcac catgaagaca 117900
          agaaggccac cggccacccc gttctggcct caggacactg accacccctg ggggtggtct 117960
          agggacttag gggaacctca tctcagccgc aggtggagca cccagtcccc aaagacaggc 118020
          tgaccgcacc accccagggg gacgccgcag cacagcccag caccaggtgg ggcagaggtg 118080
          accacggccc ctctttgctc cgtcatcggc tggtcagctg tggtcacggt gcctcagagg 118140
          acagatctct atgggggcaa gtgccagatc ctgagagcgc atgagacgct ttcccggagc 118200
          cgacgaaggg gactcggagc tgcagcctgc acgacccctg cagcctgtgc tttgcccacc 118260
          cctttcaata gatggaactt gcttgctctt ttttattctt ctcaggattc attttttatt 118320
          tcacatattt gtttgtttgt ttatttattt ccattgatct ctttaccctg aggtttactt 118380
          gcaaaatcag ggttcatttt taaagcaggt cctcagcccc agccacactg aaccacctct 118440
          gccctgacac gggaggggtc ctagctgggg tagctgggct ttagcacctg ctcactgcct 118500
          gccatgaccc ctgaccccag tcctggccat cctccagcct gtcccaggaa gagggagcag 118560
          agagcctcat ctcagcctgg agggggccga ggacgggggc agcacacggg cagtctgggc 118620
          tgtggggcag gaggccagac agggtggcac tggtgcctga ggggttgggt gccaggctct 118680
          gtgcccggcg ggggctagga tcgggggtgg caccgtcccc acaggctctg aaagttgatc 118740
          actgtcctct gtccttgcct gccttgcccc agaggcacag cctcaaaact gtctccactg 118800
          tgggaaagca gccctaggcc cctgtctggc cacttcatct tctcttggtg tgggctagag 118860
          gcgccagctg aggagtgggg gcaaagggga tggcccacct gcagcccagc cccagcccct 118920
          gggcaccttg caagcacccc ccagcccttg acatgccggc tggcctccag atcccaggcc 118980
          ccctgaggat gctggaatct gccacagagc atgaagaagt ccctggaatc ctttcttgcc 119040
          attcacctga cctctacaag aaggggccgg tgatcatgat ttgacagctt gggacaagaa 119100
          tccagggagg ccgggtctct ggcgcgcctc catgcccctt caagaaggtg ctatcctggt 119160
          gttcctgagg agcagggcga gcctgggcct gagggaacag gtacacaggc agcagcactc 119220
          agggccgggg agtgctggcc ccacccgcct gcgctcactc gaaagctgct ttggagggct 119280
          gggctgcagg ggcagaggct ctggaaaaga ggcccaggct gtgtagctgc ccttccttga 119340
          tggagcagac tctattctag aaatttctat aagaagtaga ctcactccag gacaagtggg 119400
          gctgggggga gcggatgccg aggggctctg cgggcacctt gtgcctaaag tcacgggggg 119460
          cacaggagag agcgggaact aggtggactg ttgtggctgc catccatcgg caacgctggc 119520
          cggaaccaga tgagcagtgt ggggcgagag ggagccccag tgcggcccct caggccctcc 119580
          atgcttcagg gtgtcagtgg ccccggactg gcctcactca gccctgggca cttgggcctg 119640
          tcggggatct agctttcagt gaggacccca ccggtggact gaggctcccc tcaccgtggc 119700
          agaggaatct ctgcccttcc caccgaaagg ggcaggagct agtggatggg gacggctcac 119760
          ggccctccct ttccacttgc cttggaaagg gagaggcagc agacaggaag ggccttggaa 119820
          ctcaggccag tgtggggaga gtgtccccag agagtccttg gggtgggaga ggggtggagt 119880
          tgacagccgg tgaggccggc tttgaggttg tgtggaccct gtctgcctct agctcaagtt 119940
          gggaggggtg tcagctgtgg agctgtgtga gcctcgggga cagccacatg tggggtgcag 120000
          accggtctag atgtgcctgt ctggtgggcg ctgaaggtcc ccttgggaga gtccagggca 120060
          gcacctgata agccgagagc tgcagccgtg tccacctgga acctgtttcc tcaccgggaa 120120
          catgaacacc tgcttcagaa gctttggggg ttaaaggtgg ggatacacat aggtctcttg 120180
          cccagcggtg gacactcggt acactcctaa taaatggggc atggggtggt ggagtccagc 120240
          acctggctgg gcccaggaat gaggcatcag tggtcggagg gaagggcgtc tgcccaccta 120300
          gcatctttgg caaggatctg cctcccagca cccctgtgga gtcctgtctg gatgggaggg 120360
          agagcagggc cgtggacagc ctccagaggt gttcccctga aacctctgaa tgtcaccagc 120420
          acaagcaggc tgggctgggc tctcccggca gtaacaccaa ccgagcacag ccgttgtcct 120480
          ggggcatgcc gtccaggttg ggggacaggg aggcagaggt cccgtgtcat tgcccgtgag 120540
          tccggggctt aggcaccgct ctggggaccc ctcatgctgg cccccaggcc cactgaggca 120600
          taggtgagac cattgcatgg tccttggaag aacagggctc ctcaggcagg gagtggacag 120660
          agccaatgct ggcgatgggg gaccttgcct caagcagagt cgtgggagat ggagtcatgg 120720
          gggcgtgtgg gggtctaggc aggggagctg ctgactgcag gtgrcccagc agtacccagg 120780
          tttctgctcg ctcccattcc acctccccga gggcactcgt gggaaaggga aacatggcac 120840
          ccagctggtg cctcattcca cctacctcct gagtcaaagg gctccaccac cccagacaca 120900
          cccagagcct ggtgtccagg atgccatgtg tgtgccccaa gccagtagga cccttgggag 120960
          gctcagcacc ccctgcccca aacaaatgcc tctcccctct ccacactcac tggcattccc 121020
          acagaatgcc ctcctgactt ctagagcttt ccctgtccag agctccggga gcacaggtgg 121080
          cagggaatta gaggcattag aagcacagtg tggaagctgg gcagagctgg ctgagatccc 121140
          actgtctctt ccaggctggc cttgagcaaa gctcaaaacg catcccacag gggtcagtac 121200
          ctgcccatgt ggtgggggat attccaccag gtgaagtgtg taagggctca gcagggagcc 121260
          ttggcacatg gtgagtcctt ggtgagggaa ggctgttggt ttggagaggt gaggcccaca 121320
          aggccgtcag tccgccatgc tgtgccaacc ccagtgatga gaggatgaag ccaggtcagg 121380
          gaggtctcat ctaccaggct cccacctgag ctggcagctc ctcacgccat cccaagccat 121440
          cagaactcag gtcctcgaag ggaggcctgg ctgccccctt cctctggagc cagacaggac 121500
          cacacctcct gcgccctggg gcttcactcc aacaggggag cttcccaggg ggccgggaga 121560
          ctcagaagaa atgcccacaa ctgcctggca tgtggtaggc tttgcacaaa gagcagtagc 121620
          ttcaacccca atgacccacc tctgtgaggg gggcagagat ggctctgggc tcctctgggg 121680
          ctggaggtca ggctctgctt aaaaccgttg gttcctcaag gaccatgggt gtcaggtggg 121740
          cctccccagc tgagggcctg gccaggacct ggtcaggggg tccttcattt tcccctcccc 121800
          ttgcaagaag gagcaggcca gagcctggag ataagtttgc agacaatttt tacgtgagta 121860
          gtttatgttt gttttgagat aaaagtcatc atttccacta caactcattg acttttggta 121920
          tattcacaat catgtgcaac catcattact gtttagttcc agaacggttt tttaccccaa 121980
          agggaaaccc catatccatt agtagtcact ccccgttctc ccttccccag accctggcac 122040
          ccagcaaggg cttcctgtct ctggacaggc ctgttgtggg caccatgccg acgtggaatc 122100
          accgtgtgtc tctggacagg cctgctgtgg gcgccatgca ggcgtggaat caccgtgtag 122160
          tcttttctgt ctggcttcct tctcttggca taatgttttc aagatgcacc tgtgtcgtgc 122220
          caggtgtcag gacctcattc ttctttatgg ctgagtcata ttccatcata tggatcagta 122280
          taaacatttt gttaatcctg gtggatattt gggttttttc cattcagggc ttttgtgaat 122340
          aatgctgcaa tgaagactga tgtacacgct tttgtgtaaa catgttttca gttgccttgg 122400
          gtatatatac ctaggagtag aatttctggg tcatgtggtg accctgtgtt taactttctg 122460
          agaaactgcc agacttttcc atagcagcta catcagttca catccccacc agcaatgccc 122520
          aagggttcca ggttctgcac accctcacca ccacttgcta ttatctgccg cttagattct 122580
          agccattcct tggagtagaa actggtgttt cggctgggca cagtgagtgg ttcatgcctg 122640
          taatcccagc actttggaag gctgtgacag gaggatcact tgagcccagg agtttgagac 122700
          cagcctgggc aacatagtga gacctcatct ctacagaaaa ctaaaaaatt aaccaggcat 122760
          ggtgatgcac tcctataatc acagctactc gggaggttga ggtgggagga tcacttaagc 122820
          ccaggaggtt gaggttgcag tgaaccgtga ttgtgccact gcattccagc ctgggtgaca 122880
          atgagaccct gcctcaaaaa aaaagtggta tttcattgtg catttgattt gcatttcctg 122940
          atggctaatg gtggtgagcg ccttctcatg tctagtaacc atttgtatat cctcgtgagc 123000
          aaagcatcta ttcaaatcct ttgcccattt taaaaattgg gttgtcatct tgttgagttg 123060
          cagaagttct ttatatgttc tgaatcctag atattgatca cttctttagt ttacaaatat 123120
          tttttcctgt gggttgtcat tattttcttg ttagtgtcct ttgatgcatg aaagttttta 123180
          aatttgatga agtccatcta ttttgttgct tatgcttttg atgttagatt taagaagcca 123240
          ttgactaatt caaggccatg aaaatttaca cctacatttc cttctaagaa atgtatagtt 123300
          ttagtgcttc ttacctttaa gtctttgatc cattttgact taaatttgtg tatggtgtaa 123360
          gggagcaggt cccatgtcat acctgtgagt agccagttgt cccagaccat tttgctttgt 123420
          tgttgagaca gggtctcgct ctgttgccaa gactggagtg caggggtgtg atcatggctc 123480
          actgcagcct cgacctcttg ggctcaagca atcctcctgg ctcagcctcc agagtagctg 123540
          ggactacaag catgtgccac catgcctggc taattttttt ttttgagaca gagtctcgct 123600
          gtgtcgccca ggctggtgtg cggtggcgtg atctcggctc actgcaagct ccgcctcccg 123660
          ggttcacgcc attctcctgc ctcagcctcc tgagtagctg ggactacagg cgcccgccac 123720
          cacgcccagc taattttttt ttttttttca gtagagacgg ggtttcaccg tgttagccag 123780
          gatggtctcg atctcctgac ctcgtgatcc acctgcctca gcctcccaaa gtgctgggat 123840
          tacaggcgtg agccattgtg tccggcctag tttttcaaga tttttttgta aagacagggt 123900
          ctcaccatgt tacccaggct ggtctccaac tcctgggctc aagctttcct cccacctcgg 123960
          cctccccaag tgctgagatt acaggcgcga gccactgcac ctggcccatt tccacttcct 124020
          cctttccact ctgaacgcct tttatttctt tttcttgcct cattgctctg gctggaacgt 124080
          ctagcacttt gttgaacgtg gtggtgagag cacacgtcct cgtctcattc ctgatcgaac 124140
          gcggtggtga gagcacacgt cctcgtctcg ttcctgatcg aacgcggtgg tgagagcaca 124200
          catcctcgtc tcgttcctga tcgaacgcgg tggtgagagc acacgtcctc gtctcgttcc 124260
          tgatcgaacg tggtggtgag agcacacgtc cttgtcttgt tcctgatctt aagggaacgt 124320
          ttgcagtctt tcaccactag atgtgatgtg agctgttaga ttttcaagga tgctcttcat 124380
          ccagctgaag acggtccctt ctagtcctaa tttgttaagt gtttttatcc ttaaagggta 124440
          ctggattttg tcaaatgctt ttctggcctc tattgaaaag atcctgtgtt cttctgtgaa 124500
          tatgaggtgt tacattgatt gattttcata tgttgagcca gtttccattt gtggaataca 124560
          tctaactcgg tcatggtgta taatccattt actctgctgc tgaatgtgat ttgcttgtat 124620
          tttggtgcgg atttttacat ctgtatttat aagggatatt ggtctggtgt ttttttatga 124680
          tgtcttcctt tggttttgat atcaggataa tattagcctc atagattggg ttaggaaatg 124740
          ttctctcctc cgtttttttt ggaagagaga gattggtgtt aattcttgct agaacctttg 124800
          gtagaatttg ccagtaagcc tatctggtct tgggtctttg ggaggatttt gattcgattc 124860
          aatctatgta tttgttatag atcgttcgga ttgtccatcc ttgagtcagt tgctagcttg 124920
          tgtgtttctt ggagtttttc cgtttcgtcc atgttatctc atctgttggc ataccgtcgt 124980
          tcacgggatt ttattgatgt gtgtgaggtc tctgagaacg tccctgcctt cactcctgct 125040
          tttagtcact ggcatcttct tttaacttgg gccatctggc cgtgcatggt tttgggagag 125100
          tcctccttga ctctgcagat gctgagcagt gatctggctg ggaaagggga ccaggagtgc 125160
          agggcacctg ctgaggactc acctaagccc aagagtcaga gagtcggagc tccaaccaca 125220
          tctgcctgca tgcctttccc aggctctccc caggcggaca gccagcaccc cctccccaaa 125280
          gaccgggcag ttcctgacca gcaccccacc aagtcctcag taaggcctgt ctttggggga 125340
          gcagggtttc aggaggacag tgggggtggt gtagaactca tggctggcgg ttccgggcct 125400
          ctcaggaagc tttgccactg ggcttggggt taagtgggtg tggggctccg aaccctaaat 125460
          gggtgagagt tgaaatgaaa gcggcacctg tagtccgttt ggggtgcagg tgtgtgccag 125520
          gggtcttcag ccccggctga tggccacatg aaccacatga ggagaggcag ggcgtgtcag 125580
          cagcaaacct aagtgtgtgc tcatttctgt gggcccttac tctgtgacac tgcagctctc 125640
          cagagagacg ctttgaaaac aaaacaggaa agaacacacg gccccgcgtc tgttgcctga 125700
          gtcactgtat tccttaaaag gtgaaggacc ctggtccttg gcttttcgtg cacatgagaa 125760
          aatgttggcc aaggttagcg attatgcttc tgtaatctgt aaccagaagt gctcttatgc 125820
          ccaaaccttg atgtgattct gctgtaatgt aacttcggag ccagctggat ggatgtgact 125880
          gtgcaggtcc tgagccccgg cccccgtaac caagcagtgg gccgagacac tgagccgggc 125940
          agtcaaacag gagctctcta aggctgctcc cgggctggga cctgggtcta ggattctcag 126000
          taagaccttt gaataaaact aacttgaatt cttcaaaagc ttgatttttt ttcttcagtc 126060
          aaaagcatct tgcagagatg ccagcccacc gtggggatgt gcagtggcag ccctgagctg 126120
          gcccagcccc tttccccaag gctgctctgg ggaggggggc gggtttgggg gagtagagtg 126180
          caggggattg aagcagggga aacagggtgt gagggtcaag gggggctaga attgggggag 126240
          caggttcacg ggccaggggc tgggcagggg tgggcctggg cacctggtag gtgggggagc 126300
          cccaacttcc catccctgcg tcacacgccc ttcccctgca gggtgggggt ctgcagggtt 126360
          ggcatgtgcc cccctgccct gtccccaccc tactccccgg cggcaggcag aggggcgtgc 126420
          aggggggccc taagtgcagt gacgtctcga ctctgactcc gacccacaga actttaaaaa 126480
          tagggccgtg gtaaagtccg tctctacaga ccacagcctg cccagagcta agaatattct 126540
          tgaaccactt aataattcaa gtcagatcca aatagatttt cctgctcact tgcgggcctc 126600
          tgtgtccctt tcccaggccc ccaccctgcc tggaggctgg gagggaaaga ctccaagaag 126660
          caggtgggcc tggcctttgg agcctctgag accccagctg tcctgcgtcc cctctcctgt 126720
          ggcactcagg atcagaagac acaccagggc tggagtggtc ctttaggatc tggccaaggt 126780
          caggccccag ggaggggccc ctctggtggt cctagctgtc ccaagcccca cccctgctct 126840
          ggccacaggc attggactat ttgaatctgg gtctgagctg ggccttggcc ccttgcacag 126900
          catctgacct gagccacgca cctctcatgg gggccccgtc ctccagggcc aagggcagca 126960
          tgagctccag gagagccagc ctcgcccctc acaccctggt agctggtaca cgcccacccc 127020
          agggcctgtg tcctgcctcc tctgcggaag agtccctgaa gggcctggcc tggggctcct 127080
          tgtcctggtg gaagtggctg tgcacaggca accagggccc tgggttccag accaaggcct 127140
          ctgtacttgt gtgctgtgtg tgcttgggta agccacctcg cctctctgag cctcttatca 127200
          gtgggaccga tgcttttaga ataagctgtg gtgtttgggg caggaagggg tatctgacgg 127260
          gtgccctgag gcctgagtca ccctctcctc caggggcagt gcccaagctg cagacacccc 127320
          tcacccatcc ctgtctcccc ccaggctctg gtctttcaaa caggaactca gggtgaaggg 127380
          gtgccacctg ggaatgtttg ggggagccca cacttgctgg cggggaagtg ctcaccagcc 127440
          tggcccccca accccggcag cagcccagcc ttagcagtcc ctgctgaact tccctggcca 127500
          ggccccgagt ggagttttac caaattatta attaagggca aagccatgct gcagcgctga 127560
          catccagatg aatagcacgc agtgtaatta ggcgaggtgt catggagatg atggagtaca 127620
          gcctgctagc cccaattcac ctccccggca agcaggagca acttctctgt gtcctaccac 127680
          catgggcggc tggtgtgggg ccagtagggg tgtggctaaa ggggccagct gacagctatt 127740
          gcgggtgcca cgggccctgt ggacagggct gggctcctcc cccagggaca ggcacccctt 127800
          cccctctgat tgccatgggc agaacccaaa agggagtaaa gtgcagaaag gggcaggcaa 127860
          ggtgggaggc aggctaaggc aggagggatg aggaccagga caaatccaca gatagacccg 127920
          gagcagccca gagaggggca tggagggagc acaggagggc cgagaggggc cggggaggag 127980
          gtgcagaatc caggaagaca ggacaggcct cggggcccta ccctggggtt gcctgggcct 128040
          gacagagagc tgggagcggg gagcagcttg agaatttttg gttttgtttt ttagttactt 128100
          acattcatgt atttttggtt gtttgagacg gagtctcgct ctatcgctga ggttggagtg 128160
          caatggagca atcttggctc actgcaacgt ctgtctcccg ggttcgagca attctcctgc 128220
          ctcagcctcc tgagtagctg ggattacagg cgcccgccac cacacccagc caatttttgt 128280
          atttttagta gagacggggt ttcaccatgt tggccaggct ggtctcgaac tcctgacctc 128340
          aatgatccac ccgcctcagc ctcccaaagt gctgggatta cagacataag ccaccgctcc 128400
          ctgcctacat ttcatgtatg cttttaatca acatcataaa ttgacagttt taataatcga 128460
          atagtactac aaggcttctg acgaaaaacc acacctcttt cctgattccc ccttctcaga 128520
          ggcaaccttt tctgtgattg tagctgattc tctttggtat ttacttccga atagccatgc 128580
          tcatgttgct gctggtgctg cttttttttt tctccttttc agattgagaa atttacccat 128640
          gtccttccca cgatggcggc tgaaagcttg ttctctcaca cgtgcccccc cacactctcc 128700
          caccagcttc tccttttgat tgaatcagaa ttcaatgtat gcactattat ttctcagcac 128760
          acactcttcc cagctgagta atgtattgta attacatttc ctttcttgta caaccactta 128820
          tttttcctgg acttaataat tgcctcattt aggggattgg gttgatattc tgtgtaccca 128880
          ttacttattt atccccaaac cctgccatgg aagtataaat ctccttttgg ttcattaaaa 128940
          acatccggcc catctgggca cagtggctca cgcctgtaat cccaacagtt tgggaggccg 129000
          aggcgggaga attgcttgag cccagtagtt cgagaccaac ttgacaacat agcgaaaccc 129060
          catctccatc actatttagt tttaaataaa agatattttt aaaattaaaa acatccaggc 129120
          caggctgcgc tgggcccgcc tcactgtagg gggctgcgct gggcccgcct cactgtcggg 129180
          ggctgcgctg ggcctgcctc actgcacggg aagtgtgctg ccgctgtcct tggtgctgaa 129240
          gtcaaggctg gggccggagc ctctcctcca gcctcactcc tcttcagctt ccgccctgct 129300
          tcgcctccat tcctgcccaa gaccccctgg ggagcagacc ccaggccctc ctcaagactg 129360
          ccgaccccag ccctcgtccc agcccaggcc atctctccca ggccttgcct ttctgtacca 129420
          ggtggtcttc ctccccaggg ggctcctccc cgcagccctg gcagacagct tgaatcctgg 129480
          agttgcagca ggtgggtgtc tgagtggagc tcccttgtgt ataatcagaa ctctccaggt 129540
          tacatgtgac aaaaaccaac ttaagcaaag ctgggacctc gttagttcac tccaggaggc 129600
          agcgccgccc tgcatggcct ggccttggct ccctccctct ccgggaggct gctccctcat 129660
          cagcccagcc tcacttcctc acccacataa caatccttgg cagagtgagc cctgctgttc 129720
          cagcggcccc agtggcccca gcgaaggccc cacgccgaca cttgttggct ggccaggctt 129780
          gagtcacatg ccttcccctg aacccctcac tgtggcctgg ggtcgggggg ccaagtgccc 129840
          agtgcagagc tagggcctgg agcagcctca gtgcaccttg tggagagggg gacttctcag 129900
          tagaacagca ctcttgccag gagaaggaac acctggttga gaaaaccgag gtcaggtgac 129960
          cttctcaaga agggtcagtg gcttcaggat ctctcataaa gcttcatctc caaggcccaa 130020
          ggagagcaac agtgtcccat cttgtctcca ggtaattcta ttccggtgcc agcagagaac 130080
          agcgtgatta agcctccatt attaacttgc caatcttgtt tctggggcac agacgctaac 130140
          ggcttagggg acccagttgg catataatga ggtctccatg acaaattact tggttatcaa 130200
          ttaactatct ggggaaatgt caagcaggat ccatcatgct ggcaggaaga gagagccaat 130260
          taacccaggg cagttcatcc aacccaccgt cgctgcgtcc agcagggcca ggaatgagag 130320
          aaagggcctg tggagcccag agcagggcag ttcctccacc cccccaggga cggtgtgaca 130380
          ccggctgcgg ctacactggt ggcagcttct gcagtcatgc ctcgcgtgct cggcgcacca 130440
          ctcttgcctg tacctgtctc tgtccattca ttcattcatt ccacagtcac ctgcatgtca 130500
          gacctggacc aggcacggat gggagaggtg actgagggct gaggttaggg agggacacac 130560
          gtgcagactg cagacaggtg tccctgtctt gtgtggtctc tgcagtcagc aagatgggta 130620
          acagcatcct caggacaggg aggaaagaag agttcattct aaaggtggtg gggggacaga 130680
          gagagcatca tagctgggag gagagaagag ttcattttaa gggggtgggc gggggacagc 130740
          atcacagagc tgggagaaga gttcattcta agggggtaac ggggggacaa agcatcacag 130800
          agctgggagg aggagagaag agtttgttct aaaagtgggg ggcacagaac atcatagagc 130860
          tgggaggaga gaagaattca ttttaaggcg gtaaggaggg gacagcatca cagagctggg 130920
          agaagagttc attttaagag agggtgacag agtgtctcag agccaggagg aggagagaag 130980
          agttcattct aaggtggggg acagagcatc acagagctgg gagaagagtt cattctaagg 131040
          ggcgggggac agagagacac agagagactc tgtgacagca tcacagagct gggaggagga 131100
          gagaagagtt cattctaagt gggggttggg gggtgggggc aggacagagt gcatcacgga 131160
          gctgggaggt ggaggaggag aagccaggtc cctgagacaa ggggcagggt gggtggccac 131220
          caggcagagg gtgcccaggc acagcagggg acggggctgc tccaggcttg ggcaagggac 131280
          cattgactgt gcactgtccg gacctgagca gaatctggct ctgccgtcgc tgtgctggga 131340
          gaccttgaaa cagtttagta aaacctcgcc gggcctctgt tttcttatct ataaaatggg 131400
          gataataacc cccagttctg ggagtgttgt gggaactaac actgtggccc ccacttggtg 131460
          ctggctgaac ctggttcctc cttctcctcc ctacaagaga ggccttggac ccacctcact 131520
          ggtgaaggct cccagggtgc acatgccgga gcagaggcgc agggaggagg gaggcatcct 131580
          ggaggaggtg gcttgggctg tcctggagga gggaggtggc ttgggctgac ggccggcaca 131640
          cggacgggcc cgaggccgag tggcagggtc ggggactttg gtcacttatc aaagtcaaag 131700
          cccaggactt tttgggtttt gctttgtttt cagcaaaggc ccttgggtca cctgcgatgt 131760
          gtcccaccct tgtgagaacc agtgacgaag ccctggccct accctgtccc ctggcctttg 131820
          cctgtgcccc caccccgccc ctctggtagc cccctcccct tgcctacttg ggggtgattg 131880
          gcagctgcct cttcccagcc ccccaggcca tggcacggag cctcaagcct attcatgatg 131940
          cggacatatg gcacctccac ggggggcttg gaggaaactg ccaattgcga gagtgcagcg 132000
          tgtccccatt ccagccctgc cggagcaaaa caaacgcaag tcgcgagggg agcagaggcg 132060
          gcccgggggc gtgcgcatgt gtgcgggtgt gcctgtgtgt ctgcagctca caccgcgggg 132120
          gtgccgggag gaggggggct gcccgatcct tgggagtctg cggctttcag acgctcctgg 132180
          gggctcggct actggggtcc taaggaggcg agctggcccc ctcattccgc cccgcaggcc 132240
          gtgcctctcc tgtcttgagg ccgcttttgc ctccccacac ctcttaccca ggacgctggg 132300
          ctggaggctg tgaacagccc tgggagcaga tcccagagat gctctcattc tttccggaat 132360
          caggacgttc cccccagtgt caagcccaag tccccagggc tccaggctta gccaaactct 132420
          tctgttttat tggaggtggc accaccccca tatcagtggg ggcactgcag ccaccagtgc 132480
          atggccccct aggcccctgc cccatgctgg gctcaccctc ctgtgcccag ctggggaccc 132540
          aggcatgaca aagccctgct cctgcggcag gggagggcgt gggggggtgg gggggcgtgg 132600
          ggagggagtg gggagggctg caggggaggg cgtggggagg gcgtggggag aggctggcca 132660
          aaggccaggc tctgggggtc tcagcacact cctctcccga cccagggctg gaggctgctg 132720
          ccatggaaac caggcctgtc cacccactgg ccatgtgcat ccaggggcca tggccaccac 132780
          ctcctagcac ccagctctgc cccccacccc cattcggggg agtgagaagt caggagagag 132840
          aggaagggcg ctaagcagaa cctggagggt gggcctgggg taccagaggc tgaggtgctc 132900
          aggcaggcta agggtaaggg gcctgtcccc tgagccccag ctgagggtct aaccctctgt 132960
          gctgctggga agctccagac cctctgccac aaaccttggc atgcacttcg ggcagtggca 133020
          gcccctgtgg ggtgtgtccg tggcacccat cagcctcctc cttgtggctg gggcctagga 133080
          gcagaatctg cacgctttgg gccttcccca gggagtcagg gaggcgaggg tgcagcccgc 133140
          tagagagtgg cccatccatc agttccctcc caggagcgct ggctggggat gctggtgggg 133200
          aggggctgca ggggcggctc tgactccagc tctgccgaca ccctgtcccc agcactggca 133260
          ggcacctggg tgtcctaatc tgtctatagc ctggccttgg acgaggggcc tctgccccag 133320
          ctgggtgggt gtttcagggc ccaggccccc accttggctg gcagcgtgca cacccgccac 133380
          aggcactggg ccgaccaagt tgcaggcacc actgtgcatc caagcatctg ctgccgccgt 133440
          ctcggggcag atgggctgcc agtgagctaa gtgtgtgcgg gggaaggggt gccataggaa 133500
          cccctccccg ccgggagcgc gggggcggga gaggcaggca cccgccggtg ggggagccgg 133560
          gagccatcag agggaggggg gctgggatca catgggctcc agggttgggg agaggcccat 133620
          gcagcccgtt cctgggccag gggctcaggg gatctgggct cagcctcgga ggatgcagag 133680
          ccttagaggt cctgatcagg gctgggagac ctgtcacccc tggccaggtg gccctgggca 133740
          agtcccttcc ttctgcaggc ctcgggcccc aggagtgtgt gtggatggtc tagagggtgc 133800
          cttcccgctc cggagccctg tgccttggca ggatgaaggc gtcctccgca cacagatgcc 133860
          tgccatctgc aggggcctcc tgccagggga caccagcaca ccctgccaga ctgatccggg 133920
          gcacgtgggc tacacctccg ccccttgctc caaggctgtg gctcccagaa aggctggggc 133980
          catgctgtgt gttaagtgag gccacttcgg agtttgccag ctttccccag tccctgcctg 134040
          gccacagcag gagccccacg gtgaggggac ctgccaggct gggcaggatg ctggccaggg 134100
          tagaagatcc tgccctgccc ctgctgcccc ccaagcccat cacactgtat ccaagacccc 134160
          tcaggagtac tgggatccga ggaaggaggg agtgtgggag agttggcaag gagacagccc 134220
          aaggccacca acagccttgg aagccgattt gttggggcat caggagggcc ttgagcagag 134280
          aagacgaccc cacggacaaa ccctgcagca tccctgctcc aggagagggg tgcccacccg 134340
          gcctcagggg gcttttcttt catgatggca gtaaacagag caaagttgtc tgtgctcagt 134400
          ccctgtcctg tgccagaggc tgctctgaga actcagctct tctgtaattg gcacaagaat 134460
          gctaagagcc acccttatgc ccactagaca gaaaaggaga ctgaggctga gcaagctggg 134520
          gcagctggcc ccggccaggg gccaacgaat ggctgagctg gaatttgagc ctgaagtctg 134580
          cttgacccct tgggctttct gaccagagca ccccactgga agggcacgtg tcctccagga 134640
          gaggctgcct ggtgcctcca aaagtgcagg gaaatggggc aggtggcccc tctgtgcccc 134700
          ctcccccacc aagcctaagg gggcccccat cgccaccatg gctctctcgg attcaacaga 134760
          tgcctccgcc tggctgtgac tcagcctctt agtttgttgg tggttgcctt tttttttttc 134820
          tttttctttt ccaaagtatg acatcgccac tgagccttgg cagagtggct cccaggacac 134880
          tggcaggtcc ctcccaggcc ttgctcagga gtgcccatgg gtggccccag cttgcagggg 134940
          ccaaggtggc tgatgaccag atgccatgac aggcacccca aaagggcctc gcccttggac 135000
          tgtggccctg ggcagactct gttaccttca aagtaggcac agcccatccc ttagttgcac 135060
          ctgactgggg cacagtgccg gggacacctg tccaaagtca ccctccccag ctgcctcaca 135120
          gcccaaggac atctgtccaa agtcaccctc cccagctgcc tcacagccca aggacatctg 135180
          tccaaagtca ccctccccag ctgcctcaca acccaaggac acggcgcgta cttgacgttg 135240
          cagattgggc cagaaaccct cctgggggga ggggcccaga gccctacttt tcacgggtgg 135300
          gctaagaaac agaggatgtg tcttggagaa gacttgcagg ccaggagcac tgcccattgc 135360
          caaggccagt gggctgagtt ccacggagag aaaaaggctt tccctccatg aaggaagctt 135420
          tcttggcatt tgggactatt ggtagagccc acagtttttt ttgttttttt ggttggtttg 135480
          ttttgtttta tttttattat tttttttttt tttgagatgg ggtctcactc tgtcacccag 135540
          ggtggagtgc agtggtgcaa tttcgcctcg tggcagcctc gacctcctgg actcaagcaa 135600
          tcctcctgcc tcagcctccc aagtagctgt aactacaggt gtgtgccagc acacccagct 135660
          agtgtgtgtg tgtatacaca cacacacata tatagtagag acagcatctt gagatgttgc 135720
          tcaggctggt ctcaaactcc tggcctcaaa cagtcctccc accttggcct cccaaagtgt 135780
          tgggattaca ggcatgagcc accgtgcctg gccttagcct gtgttttgtg aggtggtgag 135840
          ttccctgtcc ccagaaggat ttcagcaggg atagcattcc tcacgggact gagtccctgt 135900
          ggtgcaatca gagaaaagag tcactcacag ctggagttgg tcatttcagg ttcaagtcca 135960
          ggcgtgtctg tgtgaactca ggagcagggt attaaacctc tctcctcatc tctgaaatgg 136020
          gatttgggtc tccctcaaag gcagttctga ggtcaccctc aaaggcagtt ctgaggtctc 136080
          cctcaaaggc gagactgtgt gcagaatgtg tgcagacatt ttcatgcccc agtctgactc 136140
          atggccctgt gcatcttgac aggtctctgt ctctgggagc ctcatcagaa gaaatggctt 136200
          aaactccaca gggcgggatt tggggaggag aaagagcttt gggctatggg gagtcaggag 136260
          acgaggggat ggcggggctt actgtccttt cagtgacccg agaaagaggc tggcttgggt 136320
          gagaggaatg gggcagcttc tcttgcctct gggactcagg agaacccagg gctctgaggc 136380
          ttggaggggg tctggaagct gttggggggc aggtggggcg ctcatggcat gtagaactgg 136440
          gacatgccag gcaacagtga ggaggccaag ggtggtggga aacaccatct ggcagtggca 136500
          agcaggtctg ggcgtaagag gacagacaat cccacgtcca ggacgacagt cccaaggcag 136560
          ttggctcctc ctgccccagc ggtcccagcc gacacccacg tccttccctc ttctcctcct 136620
          ccctccccgg ctgcccgtcc tgtgcccatt tatcatgccc atggtagtgc cccgaatggt 136680
          ggtcccaggt gtccacccac aacctcagaa tgtgaccttt tttggaatta gtctttgcag 136740
          atggaataaa gttaaagatt tcgagataaa atcatcctgc atgaagggtt aacctgaaat 136800
          ccaatgacag gtgtcctcga aagagaaagg cagagggaga tttgagaccc agacacccac 136860
          aggggaaggt agaggtggga cagtgggaga gatgcatcca caggccaagg agtgccgagg 136920
          tccccagcac ccacggaagc tgggaaagcg gcctgggaca gggtccccgc agaggaccag 136980
          aaggattttg gaattctggt ctccaaacct gttagagaat aaatgtcggt tgatttcagc 137040
          catcaagttg atgctcattt gttaatggca gcccccagag agggagacag cctcccttcc 137100
          cgtctctcca gcccagcaga ctgctgggta ttggggttgg aaaagtcttt caagggctca 137160
          gggagtgctg gggtggccac caccttctga gcaccatcct gtgcctgggc ctgcctccct 137220
          tgcagcccga gcccaggcat aggagccagc tccactcgca cctgccagcc tcagcctcag 137280
          cctcagaggt gagcaatgcc aggaagccga tgcctccaga atcccttgac caacggggac 137340
          ggcagcgggg ccctggcttt cagaacagca ggtgcgggct gctgggtcca tgcccggtgg 137400
          gggaggctgc acggttgggc ccttgttctt ggctgtgtgg ccgccgaggc tctccggaag 137460
          gttctatgag cctcctaata tcttgtattg ggttccatta agctggccag agtgggttct 137520
          gccggttcca agtggtgtgt gggatgggga agtgctctca gctctgtccc tgggacaggt 137580
          ggggggtggg cgcgtcacat gccagagatc tggggtgaag gcctgaagac ccttcccctc 137640
          ctgctggagg agagccgacc tcccccacag ggcctcgtgg gagtacaggc ggccagcagg 137700
          cccgtgggag atcaggaggg agatgtgttc atagccggca ctcgaggcac ctgggttcgg 137760
          gacacacctg ggctcgggtc acagaagccc cccattcccc aggttgaaga ggcctgggct 137820
          ttccctgggc ctggctctcg ctctcctccc ccaacgctgc tctggtcccc ggcggcctcc 137880
          tcagggccca agtcctccct ccccctgtcc tccttctctc cactaccccc ttcttagaaa 137940
          tgaagtcatc tagaaaaata atcaaaaaat agaaaggaaa aaaacacctt agaaaatggg 138000
          attttttttc cccttcaaac atttggtgag acacctccca cacggatgag tggccacggg 138060
          gcctgttttg gtgtgagaga gacttgggcc tgtacccttg gagttgtgag aggcaggggg 138120
          gcctcccagt cccacagtgg gggtctacac taggcctccc ctctgcagcc tggccaaggt 138180
          tggccccaga agcctgaggt ccccgccgat gccctgagca ggaaggccgc tgagtccccg 138240
          aggccagggt gcaaggcagg gtgggagggc tggcgggggc caggccaggg gctgcttagc 138300
          acctaagtga ggccctgcct ccggtctctc ccctcttccc acccggccca cgccgctgca 138360
          gggctctggt ttgtttattt ataattcatc ctctgcctgc ttccaagaag gctcccggca 138420
          cttactggaa agctgcttcc tgaagctccg ttgtgctcct ggcaggctcg ggctcaaagc 138480
          ccgtcaacgc ttccccatca ctcgcaaagg cagacgactc agcctggctt ccagggccct 138540
          ccagatctgg cccccaaatg cagtctttcc gccacttcct gatgtatctc ctggccccag 138600
          agggaccctc ccttacaatg cagattgctc gagggacccc gggacccagg atacttcctc 138660
          ctaccttggg atcagaccct ccctcatccc atggcgcctt ctctggtccc gacagtgggg 138720
          gacgttgaca cctctcttct gcccattggc tgtctgctgt cacagttacc tggtacaggc 138780
          tgctccttct ggccccagcc cgacctcccc ggcccttgga ggagcttaac caagtcaaac 138840
          tattgttaag gttgatggtg acaatgccag ggaaggtgga ggctcccctc tgcctccgga 138900
          gtggcattga agacggaggt gcctgcagtt ggtccccacg ctcgataggc aggaagcttt 138960
          ggtcaggagt ggggctgaga ggagccaccc tggtggctta gtctggacgc ctgactgggg 139020
          gttccatgag tgtgtcctcg ggggctgggt ggcgaagtgt gactccacgg gctggaaggg 139080
          cggggacaca gtgtggtgag aaacagcatg cagggctgca ggcggcagct ctgcagtcag 139140
          ggctctgggc tcagggagct gtcccctgag cagggaagct cacaccagaa ttggtcaggc 139200
          aacccaggga tctgtgaggg ataagagatg gtagttgtgt gaagcctcta ggctttgggg 139260
          tgatttgtta cacagccaaa gctaactgat acagccagga actgctgatg gcacagccgg 139320
          aagtcccacc cacccttgag agatcagccc ctgccttggg caggaagccc aggaggctgt 139380
          gggaagatct ctggcctgct ggaggccccg gttgctggtg ctaagaggag ggacaaggag 139440
          ggaccaggga aggggacacc ctgaccactg gagtgctgag gagcgagttg gggggtggcc 139500
          agattggggt tagcagctcg aggggcacac ctggggggct gtttccaggt ggatactgga 139560
          ggccagccag caggctccct tgaagcaagc cctcatgcca ccttcccagc ccatctggga 139620
          cctcaccaca tcttgcttct gggaggaggg tcaccctcga tcctgggcct gctgcctcag 139680
          gctgactctt ccctgctgtg gctgagtgag caagctcgga ccctggcctg agggcctgct 139740
          tagtccccct ctcagatttg caccggtcag ggccaaataa ctggcttagc caggggaccc 139800
          tggaaacctc acttcatttc cttcaagccc taattcctcc attgaaaaac agggccctgt 139860
          gcggaggagt aaacgcgaga aagcccacgg ggcatccatg catatccccc tggctcaggg 139920
          cctcagcttt cccttctgta aaatgatgct atctcttccg cttctccctc tgccagtctg 139980
          tacctccaac ttctacagag cagaccggat gcctctgccc gccggcaggg cacgtcacag 140040
          gtaaggggtg ggggctgtgc cccatcctcc accatctgtg ggctccagat cccactggcc 140100
          tggtaccatc agtcatggcc aactcccagc ttctccctcc ctcagcttaa gcagccactg 140160
          cctggcagaa ggggagccct ggcatggcag gacccttggg gactgccctc aggaagcctc 140220
          agtggcaagg gcagatgcca gctgggctgt gtcagggatc ctctgccacc tggcagacac 140280
          actacagagc gtggcctttc cctgctgccg actctccttg tcactgagtt ccgtggggcc 140340
          acagatgtcc tggccatggg ggtcaatgca gaacagatgt ccatccctgg ccacaatgct 140400
          ctgtgccaga aggacagtgc cagaatggcc ccttgctgac acagccccag aacccctgac 140460
          tttggaactg ggtggaaggg aagagaggag ccaggtgact ccatctcctg aaggaactac 140520
          ctttgggagc ccaggaccgg cccagaagca tctggctgtg gggtggccta cagcctcctc 140580
          cccacatggc tggctggcag atggctgccc tggcctgccc aagccacatg cccggcaaag 140640
          agttcctctg ccagtgccgg ggcccacgag gaagccggct gtccggacat ttgcatgcaa 140700
          ttccgggcag ccccggatgc ttgtctggct tccagcctgg gaagtggcat cgagccctgg 140760
          gaagaggaca ggcttcacgg ccacaaagag ctcaactgaa gatctgaatc ctgcatttag 140820
          tagtggtgta accggggtca ggggctttct gagcctgttt cctcctctgt aaaggaaggc 140880
          taatgtgtaa atgtgagctt gacatctaga gccacatcca gcacagagga ggcgatcaat 140940
          gatggctggc tccttccctt cgtccatggc tcacgcctta cacctgctgc tctaggcaga 141000
          aatgcccccc tgagaacccc tgagaggact tccagagacc ccaccctgga aactgatccc 141060
          accctcctcc ttctctgtga cttccacaca gcctcttcct catcattcct tcctaccaga 141120
          ctaaggggcc ttgagggtga taccaggtgt tctccagaca attcaacacc tagcagagtg 141180
          ctgcgcgggg ctgccagcat aaatcaatga catctttcag cccagagggt tctgagagtg 141240
          attgcatttg acagcacttc ctgaggcgcc cctggcctcc tgaggaatga gctgttcagg 141300
          gcatctggca agcagacacc agtccatgct ggcacccttc cttctggaga gtcacccaag 141360
          ggagccaccg atcgctgcta gaactggagc agagtcctca aacaacagtc tgcacacaga 141420
          caagacccgg gatatttctt tgatccagct cctgccttac aggacttcat cttcacccat 141480
          tcctgaggaa ggagagagga aaaaaagacc tctcatacac cccctcagtc tagtgtttac 141540
          tgagcacaca ctgtgatctg gataagagag aaactctgcc gtcttggtgc tttcagacaa 141600
          tacacatcaa attacattat caacgatgct ggatggcgct aagagccggg gagggaaagc 141660
          aagggagtac aggccacaga ccgtcctgga cttcgagttt gacttacatt ttggctttgc 141720
          catggtacaa acgccataca cattcagtat actcctccgc ttacagatgg ggttacatcc 141780
          ggataaacct accgtaaatt gccttacaat gctttaacct atgatgggtt gatggggaat 141840
          ctaaccccat atgacaggag catctgtata ggaagggggc acggttttca acaggtggtc 141900
          gcctcactaa gtgggagtca cagggtttca ggggaggagc gttccaggcc gcggtaacag 141960
          caggtgcaaa ggccctgagg caggacgggg cagggaggtc cagagtccac cgcgcagaga 142020
          cccgggaggc cggcaggcac ggtgaggacc ttgacttaaa cccaggaaag gggaaccaca 142080
          ctggggcatg acctcctgta ctttccgaga tcgctctggc tcctgtgttg aggagactca 142140
          ggaggggaag gtggaagcgg ggagacccag ctgagacgct actacagtca tctcggcggg 142200
          aaaagacggc tcggagcagg gtggtggcag aggtgggaga agaggtcagg tctggggaaa 142260
          tttcgaaggc acagccaaca ggatgtactg ccgggctgga tgcggggtgt taggggtcag 142320
          ggaggccgcc aaggctctgc ctgagaactg gggagggcca ggggcaccat ttacggagct 142380
          ggggaacagc aggagctcgt tttgttagca ggtgcgaggc gccgggcatt taaaggcggc 142440
          ctgacgggac cggccgaggc ggaagaacgg acagggccct gcgggaccgc gctcggatcc 142500
          gcctcctccc tgacctcggc gtccccggct actgcctcca gagccgcttc ggggccgacc 142560
          ccggggactc ttcccgcctg cggcctcgcg ccagcccggc cggctcgcct agtgcccggc 142620
          gcccagaaac gcgtggagct gggagaggcc acacaaccca cgccggaagc ctaaccccgt 142680
          cggcccccgc ggccggcacc ggccggaagc ccgcgaagcc taactctcgc gagacgcctc 142740
          ctgagtcccg cctctccgcg gttccgccag tcgccgcgct cctgtctgcg ttgctgtggc 142800
          agccccgccg tgcgtccgcg ttcccggagc cagcgcggcg gcgcgcctgt gctcggggct 142860
          tggccgtagc ttttcctcag gtcccgcgcg gcgcgcccct gtgtcgcagg cgccctgccg 142920
          ctgcccgcag cttttggggg gttcgggggc gggggaagca gggccgcaga aggcccaatc 142980
          ggagccttct gacacccgcc ccggcccgcc gccctcccgg agcttccgtc cccgccgcct 143040
          ggctccttac tgacacgcgc gccgcccccg gtcgcccgtt ttccctgggc tccggcctcc 143100
          tctcgcttcc agccctggcc tgaggtcctg agggctccct ggagggggcg gcttcccagc 143160
          acccagcgtt taacagggcc ctttcggcct ccctgtcccc caagctcaga gttggggtct 143220
          gcagcagggg aaagaaggag ggagactggg cagctcaagt tccccagacc gcacctatca 143280
          gacggagggc ggcccgctcc cgtcagagcc cgacctcggc ggacagggga ggggatgggt 143340
          tgagaagcgg gagaaggcca ctagctggaa actccctgac gacagggaca ccgttctcgc 143400
          cccagcccca gcgctcggcc tccgcagagc cggcccaacg aaggaagaat gaaaatatga 143460
          acgtgacatg atgtgggctt gagaggccgc cttgttcttt ggattcaccc agaaacctga 143520
          ctgaaaggaa agttactgca actggggaaa agcacagttg gctggagaat ttggtttaaa 143580
          aataaataag ttttaaatta cgtaactaac acgtgcttgg tgtagaaaat ttggaaaaca 143640
          tatgaaagta cggtataaaa atcctcgatc ccactgccac atagaaccac tattaacatg 143700
          tcagaatcgt ttcttcgggt gttttttttt cttaatgcat ttatattgca tatacatttt 143760
          ttctctaaca atatattgat gtgccccagt cccccacaga ccctaatgta tgaatgggaa 143820
          tggaggcgtc tgaaatgtga ctcacaaaga gttctctttc ctccctaaca ccccatccct 143880
          gcctcacccc ttcagcgcat tcacagcagc actgggactc cggactcaga caaatgtgca 143940
          ctgagctggc tggtgctctc atagcctctg gccccagagc tccaccttcc cctgcagagg 144000
          gggtcccggg agtgtcctca agtgctccat gccccatgtt cctttccatg gcaccaaatt 144060
          cttctgacct ccttctaggt gaggggtgag ggggtgaggt agggggttgg ggaagagtgt 144120
          ccccatgagg cctgaggggc ctgctagtgc aggggaggaa gggaagttca agcaagcagg 144180
          ctcaacggag ggctccaccc tccaggtacg gccaggtcct gggagaagga ggggaagcag 144240
          tctggtccag gagagaggca gcaagggcag atgctaagcc tttgcctctg cactccctgg 144300
          ggacctctgg ggaccccccc ccccacccag cactagtaat caaaggagga cagacaccta 144360
          cacacgtgtc ccatatgtct caccctagca ggcagcgaga ggatgcccag tgttactctg 144420
          gccccctgga aggctagctt gctctcctgg gcacaagtca gaagcagtgt gaactggagt 144480
          gggtggtggg ggacacccct cccggtgagc cccccctccg acccggctgt cagtgatcca 144540
          caagtctggc ccatcagccc tccctgctga gcacacagtc cactgaccct tcttcagaat 144600
          tgtgggaatg acctcactgc ccctccaagc aacgtgttgt gctgccgccc acatcagaca 144660
          tccggggaat ggactgcaca gcctccatgt gtgctggctc cttggcgcct gcagagccgg 144720
          gttgattctg tctttccctt caactcttgt cttaaaggat atcctgagcg tgccggctcc 144780
          tctgctcaga gggtgttagg gtggcggtgg cagtgggcac ctctctgctc ctcggctggg 144840
          tgctcagcct cgccaggctg cctggagctg gtggagcaac agccttgtcc cccgtccagc 144900
          tctctgcagc tgccctctcc tgtcagaagc tcctggaaag catttctggc acatagaggc 144960
          catctgcatg ttctcctcct gcccgcccca ccccgagtag ccacagagga tcttccccag 145020
          ctgccttcac ctccgccccc agacagagcc tcctggctac tcccccagat agtgtctcca 145080
          aaatcacttc catttctcct ctgctcgcag ccactcagtg gctttcgtta tcattcagaa 145140
          taaaaccaaa gcgtccatta ccatccaacc aaagacccca ggaacgcgct gcagtggaat 145200
          caagccacgt ctgttgactg gttgctgtga gaggatgtta ggaaggaccc gcaagtctcc 145260
          tcgtgttggg agagcatggt gggaggagga gttgggagag gctcaaggca gcagggctga 145320
          ctccacagct gggtatcttg ataactttta tctagaaggc aggaagaaca aaatgcagct 145380
          gaagctgaaa ttgatcaagc agcagcggtc attcaaatta gccaggacgg ggtggtttgg 145440
          tgacccttga ggtctggccg atgctcatgt tctgcctatg ctctgacacg atcctgtgta 145500
          tcttgcccca tctcgggcac acagtggtct tgtctggtgt tggtgttcag tgacattgct 145560
          tagccatgaa attgtctcca ggttagtgac tagtgacgcc agggtgggtg gctcttctct 145620
          ttttcaagac ctgggtgtca cctgaccccc agctgcctct gactcacctg ccactgccct 145680
          tcttatccac actcttcctg acaagctggt ttcctgtgtg gccgaacagt ttcctccttc 145740
          gggcccttcg tggtcaccgg gcccctgcct ggagcctccg cctcaggaac ccatgtggct 145800
          gactccggcc ctgtggcctt gccactctct ctccatcccc acgctgtccc cttggtggtt 145860
          cttactgcca ccttcctttc cacctgctga aaccctaggg tcttctggtc cctctgccca 145920
          tctaagaccg aattcccaca acagggagag tctgggtgac acgctggtgc gtttattcct 145980
          ggggcagtgt ggttcccaca tggatcctca gatgttcttt ggtgttggtg accccactgt 146040
          ggaccgttgg ttctgctcca agaccaaagc tggctgctgg tgggtgcaga atgcgcatgt 146100
          ggcttggacc agacagcctc taggcctccc ctttctaccg ccaggtgccg aagggccagc 146160
          agcctggaca ccccggagcc ctggagagct ctgaccccag cctctgcccc acctgaagtg 146220
          ggtctggccc cttcttgcaa caggatcagc ccccagctgg agacagagac cccacagcca 146280
          gcccagacag ccgcctagta ctccccagtc ccccagccta aggacgctcc actgtcctgg 146340
          gctgccaaaa caaatatcac caactaggca cctcaaaact catcctctgg cagttctaga 146400
          aggcagaagt ccacagtcaa gcggtcagca gagctggttc cctctggagg cttggaggga 146460
          gagtccgttt cacgcacccc attttgcttc tggtggctgc tggcaatcct tggtgtccct 146520
          tggttcagag acatcgctgc aacttctgcc tctgtcgtcc cgcggcctcc ttcccaagtg 146580
          tgcagctgtg tcctctcctc ttcttaccag ggccccagtc actggactta gggcccaacc 146640
          caatccagcc tgacctcatc ttaacttgat tacagttgca aagaccctat ttccaaataa 146700
          agccctagtc acaggttctg ggtgggcatg gatttggggt gacatattcc acccaacgca 146760
          gctcccaccc ccatgtggtg gaagcccagg gtcagggagg atccccgttc ccctgctggc 146820
          tcccagtgcg cttccaactt ccaagggggg ctcagtgggt ggtctgagct ggacacaacc 146880
          tagctccttc attcctgtga agcatcgttc tcacgggccg tctgggcagc aggcatttac 146940
          tgatgtttgg agtaatgggg acagcacttt acaggtgaca acctggggca cctcttggca 147000
          gctgggtgcc tccctgtgac ctcagctgtg acctcagcag tgacctcagc tgtgtctctc 147060
          tgcccttctt gaccccatca cctcttttct tcccctaact cctggttcca tgggctctca 147120
          cctcctctct cccaggatgt ctgagaaaac cacagtccct ctcacttttt gtccaagcag 147180
          tccagcgctc tctgcccttc accttctcct ccggcctgga cccctgaagg caagggagag 147240
          ggtagagatc acctctcaga tccagaagat ccaaaaacac ccctggggtg taggagtcat 147300
          gctgattccc tcggctgtga agcagtgcgt tcttatcgca aagagcactt ctgttttttt 147360
          cttctttcta catctgtgct aacattctgt gattcttaga gaacgaaaat tctgaagagc 147420
          aaagcccaga gccaagaatg ttcaagccag aagggatttc tatgaggaac aaaacagaca 147480
          aggcctctgc ctgcagggtg catatcccga gtggagagat ggggctgtac agacccagag 147540
          agcgtggctc gccctggaag ggaaggtcag gtgcgacggg acagaatggc caggaggact 147600
          agtttatact agggggtgag ggtcagggat gagcaggatt tagtgaagca aatgatttca 147660
          aacatcaaaa gcacaggaaa taaaaggaat atagatcaga cctcatccca atgaaagcct 147720
          tctgtgcatt aaggacacta tcaataaagt gaaaagacaa cccatagggt gggagaaaat 147780
          acttgcaaat tatctaccag atcagggatt aatatccaga ctatataaag ggcttctaca 147840
          aattcactaa ctacaaacct gatccaaaag gccaaggatg tgaacagaca tttctcatga 147900
          ggagacacac aaatggccaa tgagcacatg aaaaattctc accatcactc accaccagga 147960
          aaatgcacat caagaccaca atgaaaggcc gggcgcggtg gctcacgcct gtaatcccag 148020
          caccctggga ggccgaggtg ggtggatcac ctgaggtcag gagtttgaga ccagcctggc 148080
          caacatggtg aaaccccgtc tgtactaaaa atacaaaaat tagccaggtg tcgtggcagg 148140
          tgcctgtaat cgcagctaat cgggaggctg aggcaggaga atcgcttgaa cccaggaggc 148200
          ggaggttgca gtgagctggg atcacaccac tgcactccag cctgggtgac agagtgagac 148260
          tccatcccaa aaacaaacaa acaaacaaaa aaacacacca caatgaagta ccagttcaca 148320
          cccattagga cgactactgt ctaaaaacca gagaatcaca agtgttggta aggatacgga 148380
          gaaatcggac tcctgtgcac tgctggtggg aatggcaaac agtgcagctg ccgtggaaaa 148440
          cagtttggca gctcctcaaa aagctaaaca tagaattttc atatgaccca gcaattccac 148500
          ttcagagtat atactcaaaa gcaaggacac caacagacat tggtacacat gttcttagta 148560
          gcattattca caacagcaaa agctgggcat gacccgtgtg tccctcaaca gaggaatgga 148620
          cagacaccac gtggtttgta tacacagagg aatcttattc tgctgtggga aggaatgaaa 148680
          cactggcgct cactgcagca cggatggacc ttggcaacac catgccgagt gaaagaaacc 148740
          aggcaccagg gcagactgta ggattccact gctgtgaggc gcccagagca ggcaaacttg 148800
          taaggagaga aagtaaagta gaggttccca ggggctgggc tttggagtgg aacagggact 148860
          tagttactgc ttcatgggga cagagtttct ctttgcagta atgaaaaagt ttttgaaata 148920
          gacggcggtg atggttgcac aacattgtca atgtcctgaa tgccactgaa ttgtacactt 148980
          aaaaatgggt aacatggtaa atttggtgtt atttctattt accacaattt taaaaaatta 149040
          gtactgtact ataaaagcca tggaatcgca cgctttccat aggtgaattg catggtttgt 149100
          gaattatgtc tcattagaag aggagcattt aaaagaaaga gggaggccag gcacggtggc 149160
          ccacacctat aatcccagca ctttgggagg ctgaggcggg cggatcacct gaggtcagga 149220
          ctttgagacc agcctgacca acatggtgaa accccatctc taatcccagc tactcaggag 149280
          gctgaggcaa gagaatcgct tgaacctggg aggcggaggt tgcagtgaac cgagatcacg 149340
          ccactgcact ccggcctggg tgacagtgag attctgtctc aaaaataaag aaagaaagaa 149400
          agaaagaaag aggggcagca gcccccacat gcagccccca tgcaagagcc cccaaggaga 149460
          ggcttgatgc atcagaggtg ctgggtggtc tggcaggctg gagccaggcc actggggagc 149520
          tgggagcaga gggaagtgtg tggagggcag ccctgccccg ggttctgcag cagcccccgc 149580
          cttgtctgcc tgcactgctc tcggctggtt ctgtgctgag cgcagcctct ccttggaagc 149640
          caattttctg cacagtgaaa tgtttttttt gtgcccactt tagcagatgg ccccccacct 149700
          tggcctgaat tgggaagcac agaaatgcag caggggacag acggcttctt tggcaatgtc 149760
          ttacaggcac acgagcacgc agactcatac ccgcccccca caactcgcct tcacggactc 149820
          tgggctgcag ccggcctccg gagacctctc ctcttctgct gccgaccagc tgctggacgc 149880
          ctggcccagg tgcttgcttg ggatggatgc agatgactgc atgtctccaa ggccgggacc 149940
          ggggcgcttc ctctcctgca cccgcccctc tcggccagtc cctccactcc ccctaatggg 150000
          agaatgctga agggatcctg gcagggactc ctgacctcca gtgtggagac cccgccccag 150060
          gcacctgtct caaccccatt tacagggtag ctgagaaact tctggggaga cagcctgacc 150120
          ttggcccacc actggagtcc agaccttaaa cccactgtgg tcagtaggca ggagtctggc 150180
          ctgaggtttg aggaagggca acagagtctc cagtggggaa gtcgccattg aggaaaagtc 150240
          tagtgaaagc agatcctagg cccacgggac caatggtgtg tcagggccga gttccagggc 150300
          cagcagggag gagggggctg gtgcagggag ggttggtagc ctccacagag ggatgccacc 150360
          ggtcctcatg ggttggagcc agcccttggg caccagagag agcctgaagg ggctacagag 150420
          accatctgat cctaccctgt tgttctaatt tttttttttt aaagacggag tctagctctg 150480
          ttgcccaggc tggagtgcaa tggtgcaatc tcggctcatt gcaacctcca cctctcaggt 150540
          tcaagtgatt ctcctgcctc agcctctgga gtagctggga ttacaggtgc ttgccaccac 150600
          acatggctaa tttttgtatt tttagtagag atgggatttc accatgttgg ccagactggt 150660
          ctcaaactcc tgacctcaag taatctgcct gcctcagctt cccaaagtgc tgggattaca 150720
          ggcgtgagcc accgcgcccg gccctaacct attgttctgt gctggggtgg ggtggggaag 150780
          atggaggctt gggaggccac tgcccactcc tcatgtgacc aggtcagtct caggaaatgt 150840
          aagtgtcctt cttagaggaa ctgggagaca aagggatttt caggtttcgt ttttgttttt 150900
          gagacagggt ctcactctgt cactccaaca cacctcagct tgcagctgtg tccctccagc 150960
          ctctgactcc atcatcacag ggccgtctgt cttcctctgt gtctcttctt ttttaaaatt 151020
          tttttgtttt taaaattttt tttagatgga gtttcactct tgttacccag gctggagtgc 151080
          aatggtgcga tcttggctca ccgcaacctc cacctcctgg gttcaagcaa ttctcctgcc 151140
          tcagcctccc aagtagctgg gattacaggt gtgtgccacc acacccagtt aatttttgta 151200
          tttttaggag agatggggtt tcaccatgtt ggccaggctg gtctcaaact cctgacctca 151260
          ggtgatctaa ctgccttgac ctcccaaagt gctgggatta caggtgtgag ccaccacacc 151320
          tggcctctcc ttttcttata aagacaacac atctgcaaag accctgtttc caaatacagt 151380
          caaattcaca ggcaccatgg ttaggacttg gagctgtatt tctgggggaa acagttcaac 151440
          ccataacaaa ccaatgtggg ggtacttttt ttttgacaca gggtcttgct atgtcaccta 151500
          ggctgaagtg cagtggtagg atcatggctc actgtagcct ccacctccct ggctcaaggt 151560
          atcctctcac ctcagcctcc acagtaggtg ggactacagg cacgggccac cactcccagc 151620
          tttttgaaac tttctgtaga gatgggggtc tcactatgtt gcccaggctg gtctcggact 151680
          cctggactca agtgatcctc caacctcggc ctcccaaagt gctgggatta taggcatgtg 151740
          cttccatgcc cagccgattt ccaggtttta agggtcaaac tgttggaaac atttatttaa 151800
          aaatccagta ggagggaaat gtgtgaccag tgagtgcaga gggagtctgt ggcatttcca 151860
          ggaagcaccc caggccaggc cttgagcatc tgggagagga aggatgttca ggccacgggg 151920
          cagacgtctc cacaagccga ggccacaggg acttagctgt gcgtgagtgt gggtgtgtga 151980
          gcagccagct cctcgagctg aaggagctcg tgtgccagcg agagggtgct gctggggatg 152040
          agcccacccc cggctacctc gtagggaatg ggcacaggga gaaagcagga ctccctcaac 152100
          tgggatgccc ctgctccagg agcccacagc tgggctcaag gccgtacaca tgcccggctt 152160
          cctggagcac caaagacagg aagagggcag ctgggggacc tggagccgga tgccctttcc 152220
          caggataaat gtagggcttc cagaggcctt gcatttgcag ggggccactt taagccacat 152280
          ccccagacct tccagggctt ggtccagctt cccctgctgc tgcttatggg acctgggtgg 152340
          gggatttgac aagtcctgga gcagctcagt gggtggggag ggagagatcc aaggacaggt 152400
          ggcctgcagt cctgcgtggg ggcgggggac gcagccttca ggagctgaga aggggacctc 152460
          cagacatccg gagcttcctg gtatggatga catgggaggc actggagtcc gagggctgca 152520
          gctggggtgc cccatggccc aacctgaagg caacatttcc cagctcccct tggttctttg 152580
          gcatcccagg agggactggt gcatggggag gggcctgtgg gcagtggggg cggcgtccgg 152640
          ccttcaggag aggaacctgg aggagggtat cctggcatgg cagaaggtag tggggtctgc 152700
          ccccaattgt acctgctcgc accaggccct gtgcatatag ctcctcatcc catcttcacg 152760
          gccctgagag agagtactgc cagccccaca gcacaggtca ggaccctgct gtttagccag 152820
          gccaggcgag aacactgagc tgggagtcag gaatcctgga ttctgatttc tggatgtcaa 152880
          gctgtgcaac tctgaatgag ccacacagcc cctctgrgcc tcggtcccct catctgaaca 152940
          gtcggggaga cagactagac gaccctcaag gttctccagg cccagacatc ctgcaggtct 153000
          tggacgtagc atctctgtcc atagcgacag agacagaagt acccgccatg caggcaggct 153060
          gcccctggcc cagtgcaatt tgaggaggct gctgcatggg ggcagagctg gtgaagactg 153120
          agggaccccc gtcttcctgt gttgggacag atgggcagga gctgtagctc aatgcaagga 153180
          accaagcatg aaatgacaga aaaagaagag acgggagcgc aaaagaaaac ttgccgatag 153240
          tcagagccgt ctgaaaatag gacagactac ctctctgggg taatgagctc cacatcacca 153300
          gaagtgtgca agccgagaac agtttcaggc acctgagagg ctgctgaagt taatgacttc 153360
          caagacaccc tctggctttg acttcttgcg cccgtgtccc gctgcccaga ctcccacctc 153420
          actccaccga gctgcaaggc ccgtggcttc tttccaagca gctgttctta gctccacggc 153480
          cccctgaagg cattcatgga tgagccaaaa tcaggcgtga gaagtgcaga aagtactttg 153540
          catctaatga tagttaagaa cccaagtgtt tgaatgagct ctcacataga gattagaaat 153600
          gtatgcgtga cgttatcaca gacgtaactc tgcactttct tgagtgggag gtgtgaggcg 153660
          gtgtgtccat tggagccact ggaatcgggc ataaccctgg gcccgaccgt gagcgtgcac 153720
          cctggggtga acaccaccca gcgagaatgg ctctgggaac acaggccagg ggcctcccgc 153780
          ctggcagggc ctctgtctcc cgaccaaggc tcttcctgca gggacacagg gggttccctg 153840
          cctgctttgc tgaggccaaa ccttctccct ccacaccatc ccaggtgaca ggtggctcac 153900
          tcacacccac taaacccccg ctcctgagtc ctgggaacac cagagcaccg ggcagagaat 153960
          ccccgggcga tgccaacagg aagccagagt gaccagtccc ttccgccaac ccagtgtgtg 154020
          tgtgtgtgtg tgtgtgtgca tctgtgtgtg tgaggtgggg ggcaccaacc aaaccaccgg 154080
          gcaggtgatt ttggctccat gtcccctgac ttcaggttgt aagtgtgcta gaatcactca 154140
          ccccagggca cttgggtcct ggttactctg tcccttggaa ggaacagctc gcaagctcca 154200
          aacacatcca gagtcaagcc aggtccacaa gggggacagg gaagtaagct cagcccaagg 154260
          cccagcgttc ccatggctat ttatcccttt gtagggacac tctcagacac tctcagacaa 154320
          gtgcagggaa ggggcctggg actctgaaag cgggaaggca accacacgtg gctaaggccc 154380
          cgctagcaga ggctgaggca gagaactgcc agagttgctt gggcacgaca agcccgggcc 154440
          acctcgaacc cggacccagc tgtggaccgc gagtccaccc aggaggggaa ggggaatgcg 154500
          gagtgacccc acatcccagg ccgagtggcc tcactgagtt ggggaaacac tgggccactc 154560
          tctgcctctg cgtcagctgc ccctgggaaa tggagacccc tccacccaac atccagcatc 154620
          accagacggt gtggggttgt caaagggcac agggcaatgc acaagcgagg cacacacccc 154680
          ctgcaggtga gggtcacctg cacctggctg gggaagaggg gtggctgcag ggggaggtgg 154740
          cattggcaag cctcggaaaa gaagagacat cctgaggaga ccacagtctt tctccactct 154800
          ttactgtgta aaaataaact caacaattca tgtcatttca gcaagaaaat gaaaaaaaaa 154860
          aaaaaagcaa gaataccagt agaaatagtg catttccaga attgctgatg ggaggtggca 154920
          ggtcccatgg ttttgaccca tttgataccc aaaaggctgc agatcatatg aaaaatgtac 154980
          agctttggtt agcaaataat gaaaaagtga gatacatcga ttctctttca tattatacag 155040
          tatatacatt ataacaatat caaccatagg gggtttgctt tttttttttt tttttttttg 155100
          gcaaatgaga caaaattggg actctaagta ttgggctttt tttttctctt caatgacttg 155160
          ttccctttca acaaattgca cttcagtcca ctgtgtacag aagtaataca tttcccatcg 155220
          ttagttgaat aaatttacac actgtgttta agagatgaaa ccacgacttc gtcaagccac 155280
          atttggttgc cataagattc caaaggattc tatcctctta atgtgaacca catgtaaccc 155340
          aaggttcttc tatcaaggtt agaactgata ttcaaatcct cggctcattc cacttagtaa 155400
          gtcagctcca agacacaggt tcaccataaa tggccagttt tacctcctgg tccccaacat 155460
          gcttttgaga acaggtggcc cctctttgga gctcactgga atgactgaac ctcatgccag 155520
          cctctcctca ccccctcact gcccacaaga cacccccttg gtctcaggtc ccagggctgg 155580
          tgacaaagtg atctttgcag tcttagaaaa taaactggga atctacaaaa ggaaaagaaa 155640
          gcatacaaaa tgtatctctt tcttccaaaa tacatgcttt cagttctacg ttttggtgga 155700
          gcctgaaagt attttcaagg gagatatagg ttgagttaat ttataggttt gtccttttct 155760
          ttcataaaaa tactcttgtt tggtaataaa ctttttcttc tacagtaaga gaaataatac 155820
          tgtgttatca aaagcaagaa ggcttacgac tcaagtggga tctaagcccc tgagggcccg 155880
          gagagcttct gtcaacagct ctcccacccc ggacacccag ggagctgtcg gacaccagct 155940
          cggcaaaagc aaacactgcc tcaacagtgc tttttatctt cttgttttat aaaatggctt 156000
          acctgagaga ggcatgtatt attcagtgca agagggaaca tcaatcagat taaggagtaa 156060
          atgggaacta cgtggattag atttgcggct gtgtcatcga cctttctcgg ggccagcaaa 156120
          gtgccaagtg tcaacacagt gagggagtcg aggggcttgg ctcagaccct agcaaggggc 156180
          aggagggagc taaaggtcag cttcggccct ggcaccatgg gtgggtcaga ggaggggtga 156240
          ggaaggtgag cgggccagga ggctgcaggg gtggaggcgt aagcactggg gtgtgctctg 156300
          cccctcgcta gtcagggcag aggatggctc atggtcctga acggacagct cccacctggc 156360
          ccacgggggc agaaggtggt ctgcggtcca gtagatcggc aggggcgggg ctggccggag 156420
          gtgctggcag gggagcaccc cacacagccc gcaccgggcg ttgcctacac aagggctccg 156480
          agatggctgg agtgagggtg gggctagatc tggtctagag aggcgactcc aagctctctt 156540
          gctggctccc agctgtggga atcctttagg cttgttctca acctacacgt taaaaatgct 156600
          tcttggtgtg tttggggagg gggagaggga aactgagctc tctcttgacc tcctccaaca 156660
          cccttgactt gcttacccag ccattttcag tagctacacg ggtggtcaca gaacactggg 156720
          cggcactcgg cacacaacac agaaccgggg cagtccatgc aggtgcggga acacatgtcg 156780
          gacccaggga gcaaggaaca cgccaccccg aggaacatgc aaacggagaa gatccctgca 156840
          gatccaagga tgccacaacc cgacgggcgc tgaggaagca cgattatcta agaaaaagcc 156900
          actgttgaac aacaacgcgc agcacggcgc ctgatctgca cccccctctg cgggagtgat 156960
          gcattgcaga acggcggccg ggtaccgtgc agacacccac gagaacactg acacagagac 157020
          actgacagac acacacagat gcactaggtt cttgacacaa cgtggacctg tgtttaaggg 157080
          gacaggtggc cctagaagga acagaagaca gaaacacctg ctcctcctgc agaaatgtct 157140
          gcagctgcag ctgagccagg cagtgcagta gaatttctag aaagacttgt cagcggtttg 157200
          ctgatgagac tcctggagac agagtcgggg tgccctcagg gcgtgcgacc accagatggt 157260
          gcaaagcagg aagctcctcc taccctgggc agggcctccc gagcctgctc tctttctcac 157320
          ttagcgcaca cacacacaca acacacacac acacacacaa atgcacatac acttctctcc 157380
          cctccttgga aggactagaa ggaaatgtcc atgttgcttt tcacggggaa caaaaaaagg 157440
          caaaaaggtt ctggacactg ctcaggtgtc agtgtcgccg gccagtggca gcttgtgggc 157500
          tgctgtaggc cgtgagcccc atgagatgga ggagtgggtt tcaggcccct gccctggcca 157560
          ggcctggctc cacacgtgag gtctctggag tacccctgga ggggtctgaa ccagctcacc 157620
          tggcgcctgg tgtgctggga gggatatggc tgtcaaagtc ccccaaaaag gaccttccca 157680
          ccgatgggct gggttgaagt cccagtggcc ccatgtggcc aggtcttcat cgaaacacgg 157740
          cttctttcct taaaaggtcc cctctggtct gcactgccgg aggccaaagg agaggggtgc 157800
          tggggcccgg cttcccgggc tgtgggtggc acgctcctct ctcagggccc tctgggctga 157860
          agcagtgcag cacagctcca gaggtgagaa gggaggggca gaccccagcc ttgcaggatc 157920
          tgaggaggtg ggaaggtcga gggcagggcc gtcctggggc agagctagct gagctgggca 157980
          cacaggccga cctcccaggc cccatgctgc tctcagatgc aaacagcagg gatggatgct 158040
          gtctggccct ggggtaaggg ccagtgtcct cagccatccc ctctcctcca cgggagagca 158100
          cagggtacca tcccaggacg gcctgccttc acccttcaga gacagttcac ttctattaca 158160
          aaataaaaat tctctgtaga gagcccccgc ccccggcctt tgacaaacca ctaaaagaca 158220
          tttattacat caatataaag atatgtcgct ctgagaaagg tttgcaaaca aagacaaatg 158280
          cgtgtactga ggttgcacca accccaaagc acgcacgcag ctaacaaagt tggcaaatat 158340
          gaattttcat catgagattt ttccaaagcc agaagaaaga aggaaatgag gtacgtcctc 158400
          aaagaaaagg cctcccccag ccacgcacgc acacacgtag acacacacat gtagacacgc 158460
          acacacagat cctctcacca acttctgcct tgttcaagac gttgcagcac ccacttcagc 158520
          tgtgaatggg gcatgcctga gagagtccgg gctcctacag agaagtgggg cttcctcagg 158580
          gacagatggg agcaggggct gcttcgtgtg catgaggaca aaaccaggct gtgtgcgtgt 158640
          gcgtgtgcag gggcgacggc ctcggttcat tcctggggaa aagggagaga agagacgcac 158700
          aaaacagatc atcgccgcac aagcaggggg cgagggcggg cgggctcagc ctggcctgcc 158760
          gtgctcagtt gatctggcga caggcctcga aggtccactt ggtggcccct ccgtagatct 158820
          cgatgtggga ttcagcccag gcgatgacat tgccggacag agccttggtg ctgcaggtgg 158880
          ccaggttgta cacctccccg ggggtcagct tgcggtccca gatgttgaag tgggccagct 158940
          cacccacaaa tgcctgggtg gcatcaaacc caccacccag agtgtccttc agagaaaaac 159000
          agaggatgag agtggagggg tcgccaggtg gtctgggggc ccatccctag gccggggatc 159060
          tgagtgcctc tgtgcctgcc cgatcacgga ctctcacgga cactcctagg tgccgtttcg 159120
          tctccctgtc cctgactctc cagccctaca tccatccctc ctctggggga gcccaagaaa 159180
          agggatggca ccgaccacct ctgccctgga gcttctcctg gggggacctg gactctgccc 159240
          ctcctgcagc tggtccctca gccatggaca accacagcag ctgggcctgg ggcccctgcc 159300
          cagacatcac tccatgccag ctaaagctgc ccaacaggga cagacgtccc cgattctcca 159360
          tcccttcgtc ttcctcccag gtgcccaaca ggagacaaac cacttcacgg gaactagatt 159420
          atgcatcact aaaagcagaa ctggccttcc catgccaaag aaagtgttgc tgcagctctg 159480
          agagcgttga aaccagagct cactcctgca ggaagttcaa gtgcatgtcc acccagggca 159540
          caggccttgc ccagcctgct ccccgggctg cttctcaggg gaaccacttc tccggctacc 159600
          tccctccctc cttgctcctc ttccccttcc cagcctctgg ttctgaagct ctctcccctt 159660
          ccccaccaca tccagcacag tacctgctcc tggcccagca ccagcacgcc ctggggcttg 159720
          atggggtgat agggcgccaa gttctcgcca ctgccaccct gcgtgccatc ctggtaggcc 159780
          tcccagaccc cgtcccgggt ggtccaggtg acacagatgt ggtgccactt gccatcattg 159840
          atgacaaaag gcaacttggc cacctgggaa ggagaatgac agacgccagc tggtgagtac 159900
          aggggtacag cccagaagcc ataatcttca ctgcctcagt tgttcctatc tctacttgca 159960
          aagtaaatgt caataactat tactgaattc tcacagcacc tactgcccca gacttcagcg 160020
          tctgtcagcc ccgcctgggc gtggggcaca gaatcacaca ggaaatgtaa ggctctaccg 160080
          agggaacccc caagggccat gtgggtgtgc agtctcttca ctcctactca ccctcctccc 160140
          tctttgctag tctacacaac aagccctagt ctacaccagg gagagccgtc cctggtgtct 160200
          gagttcactg ctgcctctca aggctccgtg cgacatctgt gcagcctcct tgctggcctc 160260
          tcctctctct tccgatgtcc catctctagc tgttacaccc tctcactcta caacacggca 160320
          agcttttgcc gaggatctga gagatgtcat ggagcacgat gccttttaaa gctcagacca 160380
          gcctccaacc tggaatttca ctctcccact gccattccag gtcgggagga tgacggtcca 160440
          gcagacagtg aggaaagaaa cttcacaccc tttccgcttg gggaaagggg gcccagaatg 160500
          gcacagccct ttgtggggaa gagcaacagg aacaagggcg tggaatccac ttcccagccc 160560
          aggttttagc cattgactac cactgctggc ctggacttga gacagtttga aagctggcag 160620
          ctagttccat agctaacagg ggaggatgga gaatgttcac tagagggaaa ggctgcctgt 160680
          gctgtcctgt tccaagggat cacacagacc tgtcctcctc ccgagagtta gggggctgag 160740
          tgggatagac ttggactcag gaaaaatctc taaggacccc tcaccccgct agagcatctc 160800
          tgggtccctg ctatggaggg gcaaagccag ttccaaggcc agctggtgga ggagtccaga 160860
          tcacatcatc gggcagggcc aggccccatg gctcgttctc cgccatctcc cgtacccacc 160920
          ccaggaggca tccgggaagg tccagctctc cctgctctcc cagtacaggt gagggggctc 160980
          ctaccacttc tcctggtctt caccctcccc ctccctcagt cccacctggc aaacactttc 161040
          cttggggccc catcaacatc tgaggccacc atagccctgt ctccgcatgc aacatgagct 161100
          ggggccctgg ggcctcgccc tgccgccctg tgagcccggg ggctgctcta ccttgtcatt 161160
          gatgaggatc tccatggggt tgttgcccca ctcaatgagg accagctcgt tggcctggcc 161220
          gggcacagcg taggagaagg gcgtgcccac acctggcgtg gcgctggact tgagccacat 161280
          gcagacagtg aaggcgtaca tctctggcag gctcttcttc accttggcat acatatagtt 161340
          ggtccgcagt gggaatgtga gctggaactt gtctccaggg cggttgtctt tctgacctgc 161400
          ggaagacaca gtcctgacat ctgcacctgc gtgaagtgct tatcggtgtc tgagttgagt 161460
          tcggtcccca ccaagctctg tgatgcgtgg ccagggcagg ctccggtctc cattctggag 161520
          acgcagagcg ggtagcttcc caggtcaagt actttgcccc aaggcacagg gccagtctgt 161580
          aaagagctga cccaagctct tcatgctcca ggtctggcct gctgtcacgc ccatgtgctg 161640
          gcatccttgg ggagatgggg gtggggggca gtgcctggtg ggctgctgca tcaacactgg 161700
          gctgcgtggt gggcatgaga agggaatggg gacagccgcc aagccaagtc aacccaagga 161760
          gcaggggtgg ctgcagagga ggaacgaggc tagctaccct gagagtaacc gacctgattc 161820
          caggatgggg cggggctcag agcctctcct cgctcaatcc caggctctgc tcctgcctct 161880
          ccccacccga cagccaggcc ctggtgccca cacacttccc tccaggccag atgtgcctct 161940
          gacccaccaa tgcctcttgg gtgtgaggct gggcagctcc ccacctccaa ggcccttcct 162000
          tggagcaggg actctgcctg gagctctgct gagagggcag ggcagcaagg agctgggagt 162060
          actctgggcg ccagggctcc ccaaggtgac tgctctagga tgccgccaca ctctcaggtg 162120
          agtaagtgtc ctcacagctc aggttccagg cctggtggcc tccctttcca caaggcccac 162180
          cttctccctc cccaccggcc acttctcccg taagcgccaa cccccatagc ccatctatat 162240
          actgtggcac cctgggtatg gtgtgactga ctccaggcaa aacattcctg gccagcaatg 162300
          ggcacagtag caggcccaga gcccaggaac acacacccct tggtcaatcc ctgggtgagc 162360
          agccgtggtc ctgccaggaa gcccagaaag aaaccagttc cccaggccaa aaattatttc 162420
          tagaagacat cctgcccggt cagcaaccac cccctcctct aaaccaactg gcagggagca 162480
          gagcagggca ggccccctca gtgcagcacc ccagcggcta ccccaaccca ttgaggcctg 162540
          cagtggggga tagggagggg cccagcccct ggcctttctc cgggtgtttt tcattcccca 162600
          atctccgctc cttccctctc cctccctcct gaggtccttc cttctgatct gtttttcagt 162660
          tacataacaa gccttaagat ggcactgttt aaatctgtcc ggcacatttt gcggtctgag 162720
          cagggtcacg tggccttgct ccgcaccggg cacccccccc cctccccttt tacaaccttg 162780
          tttgatttct gcgacttcaa gacagagcct ccagcgctca tccaggcgcc ctgggtgata 162840
          gactggctgg cctgagttgg tgactgagaa acctcaggga tttgaaagat gccaggactt 162900
          gggtcactca gaaaagaaaa cctcagggta ggggttcagg acagaagtgg ggaggagctg 162960
          gagatcctga gaggacaccg ggggcatggc agccgggaag aaacctgctt aacagcctca 163020
          gcggcccggg gaacgagagc gcccagcccc agcctgcacc cagctgtacg ctgaggctgg 163080
          ggaccaggga gagacaggct ttcttaagca gggagggttt gagccagcga cagccactgt 163140
          gcaaagttac tgaggattaa acaaatcaga cttgaaaaat ccagcgagtg tgtgagtgtg 163200
          tctggatggg ggagggggca ctatgcaatc ccctttccca gagacagccc cagcccaagg 163260
          cacccagccc tgatagaaac accgactaga agcccagaac ctgggaaggg gtgcggggaa 163320
          tgagaaagcg gtgcaggggt tgggggtagc ggagcggctt gaggcttgca cagtgcagag 163380
          ctgggctgtt agggatcggg accgaggcag ggtcgggcaa gcaggtgcag gcaggcagca 163440
          cggctccccc tggccccagt acctttctcg agctcgctga tccgctggtg cagggaggtc 163500
          agggcggtct cgatcttgac cctctcctcg gtgtcgttcc tggggccccc cttgccctcc 163560
          tccagggtgt tcacccggga cagcacctgc ctctccagct catcgatctt gctctgcagc 163620
          agatccttga ggctgttggt ctggctggag gaattgaggc ggctgtactg ctgcggggtg 163680
          caagggcggg ggaaaccaca ccgttaggcg aggcgcgggg accgtgctgg aaggcccgcg 163740
          gcgcggtccc ctctgggcga ctgcgggggc ggcctggcag ggagctgggg cgagtggccg 163800
          ccgcggggcc tcgcaggcgc ggggaggcac cggccgggca cccgcgcggc tgaggcgagg 163860
          gcgggggatg cctggccggg tagggaacgg ggtgggggag ggcagagggg cgagcgagcc 163920
          ggagggggaa ccggagccga gggcgcgcgc ggacctcgag gttctccagg cgggttttga 163980
          gcgattgcaa agtttgcccg agttggctga gcgtctcggc ggccggtgtc cgggacaggt 164040
          cgcccatggt gttcttgccc gagccgggct gcttgcggcc gccgcccgcc cgggcctcgc 164100
          cggctccggg gtccagcgtg ctctggctct cgcagcggcc cagcttggcg gtcagctcgc 164160
          ggatggtctc cttctggctc aggatggtct ccttctgctg cagcaccgtc tcgcggagct 164220
          gcagcacgct gctccggagc tcctcggcgc cgccggcggc cacggacgcg gcgcacatgt 164280
          cggcgtccac gggcaccgag gtgcagatga agcgcgtcgg cccgaaatcc tgggccccgg 164340
          cgcccaggag gcagagggcg agcagcgcac aggtgcgcgc ggcgcggccg gccggcatgg 164400
          ctgcgggcac cgggcgctcc gggcccggct cggctcggct ggggctcggc tccggctggg 164460
          acccggctcg ggctgtggct ccgcgagcgg cccgcgctct gggcgccgcg ctcttcggcc 164520
          gcgcggtcca caccgccgcg ctatcaggcc cccactgccg cctgcgctgc ggagcccgcg 164580
          ccttttatgc cgccgcggga ggggcctcga gccgccgacg tcagcggggg aggaatcccg 164640
          ctttaattgt ccgcggcccg ggcccgcggc gcggcggggg tctcacgagc gcgccaccgg 164700
          ggctgcctcc gctcgcgtcc cccccgccct tctgggagct gccgcggccc cctcctcccc 164760
          cgcccccgcc tgggccggcg ctgctgcccc gaaggctccg agagctcagg gggaaggaag 164820
          tcgggctccg gccccggact cgaggatgga ccacctgcgt ggtgtccccg aacctccgac 164880
          ggggctccag gcgggcggga aaccaccgcg tccgggagat agaattcggt tcggccctcc 164940
          tggctgcact gaacaccctt gggccggggt cgtttggagc cgggctgggt gcccaaggac 165000
          ccaggtcgtc aacacccgag tgcccggtgg tcaacggctc ggagtggggc ctcgcggcgc 165060
          cactaagtcc agagcggggg tcaccgggcc gccccgcgtt tcttagatgt ccgtgtgcta 165120
          ttgagaagcc gccgggcagc ctgggtacag ggacttccca cgggtcgggg cccccggcgc 165180
          ctcccctccc ccagctcccg ggctctgtgg acccggcccc gtccccgggg gactgtcagt 165240
          ccccaccccg tgcgggcggg gcgctgggga cttctcggag gcagacctag ctgatcgagc 165300
          ctttcctgtc cgcggcgccg gcccgatcgc gggcaggcgg cgtcgccggg gctggacgtt 165360
          cgcagcggcg cttcggaagg gggccccgcg ggagcagccg cccgcgtctc cagcagcttc 165420
          cccttgccag gcgccgcgcg cgcccggtat ccccgggtgt ccacctgtgc gtggggggct 165480
          gtttcccgtc tgtccagccg cgcccacttc tcaggcccaa aggccagcag gaagggtccc 165540
          ggaggtggct gggggcgtcc acctgagaag ctccgctctc gctcagacac cccacccggc 165600
          acccgcgcac tcgcgccttc atctggaccg cggggctcgg ctcccgagat cgcggtccgg 165660
          gttccggcgc cgggctgggg gctcaggacc agggctggcg cagccgcccc gccccgcccc 165720
          gccccggggc tatcagagcg gtcaaagcct cggaaatccc tccgtccacg ctcccgtggt 165780
          acagagaagg aaactgaggc tccgagactg cggggccggg ctacagccgt ggccccccga 165840
          cccctccccg ccgcccccgg cttctctggt ctctgcgttc tgcagccttt ccctgcgcgc 165900
          agccgggggc tgggggtccc cagccagcag ggacccacgg gcagtcccgg gtgccgggat 165960
          cgggcgtccg cccctcgggc gggagcagag gccggctcga tggagacctt tttgagaaat 166020
          ggcggcctct acccgccccc cagcccccga gcgcccgccg tctgcgttca gcatctcagc 166080
          ttttaagcct ccctgagccg gggctgcgtt ctcgttgtct ccttcggccg ccgcttcctg 166140
          gcgccagagg gaccccgcgg cccgcacggg cctgtcctcg gctccgctcg gagggtgtgc 166200
          gggttcccgc tccgctggcc ccgcttgccc accacggcgc gcccaaaccc acgcggcccg 166260
          cggccccttg cgtgctctgc cgaccccggg ccgcaggagg ggttagcctc gccggtcccc 166320
          acgcggggtc tgcgccggca gcgccacggg ctggaacgcg cctcgggaga aattacccgc 166380
          gcggggtcgc ggcgtcttct gccccaactc ccgtagggag ccgctaggcg ggtgccctcc 166440
          tggccccagc gctttggcct cgccgccctc ccgcacgcgt ccagtgggga ggccgcgccc 166500
          gtcaggcctg gagccggacc gtgcccagcc gagagcgcgc gggcgcggga gaggagccct 166560
          gccctgccca gggcaggctg tttagacggg gcgggaaccc ttagcctggc cccgcgtctc 166620
          tatccccagc agccgtggag ccttcctagc cgcccaaggc cagggaccct gcctggcttt 166680
          tcctccaggg cagcagatct cagcggcctg gcacctcggc acagaggagc gtgtccccct 166740
          tccgcagagg aagggagtgg acggcgtcag aaagggaggg gagcctgggg cggtgtctgg 166800
          ggctagcggg acctctgggc actgtggggc cccaggagag gagaccctcg ggtccagcct 166860
          gcaactgttg tgcaggaggc gctgggcggg acacctgcag gcgctgcaca cacacgcgag 166920
          ggccaccatg ccgcgtttct ccttcacaag accctgggca agcggagggt cgtatttagg 166980
          attccctcgg cctccccagt gttctgaaag tatctgagag ggagggagca ggaaaacgaa 167040
          gggccgccct gcccaaactc atcggggtgt ctggttacta ggtcggaaga ggggggatgg 167100
          tgttgtgaac agccagtgat cccggccctg cctgagtccc acaccccaga tgcagctggg 167160
          gtgagggagg cgatcccgta atattcccag ccgcgtacat ttgtggctgc ctgtgacacg 167220
          acctcactca ttgggaaacc atgcacacta gcacactgtt attttatttt tgagacaggg 167280
          tcttgctctg ttgcctaggc tggagtgcgg tggcgcaatc acagctaact gcagcctcga 167340
          cctcttgggc tcaagcgatg cttcctgcac caccacactt cagctaattt tttttgtttt 167400
          tttcgtagag atggttgaac tcctcttgcc ttggtcttgg gactacaggt gcaagccaca 167460
          gcgcccggcc tagcacaata gtacttatta tactactccc accataacgg tgcaatagat 167520
          gtgaataaaa ctcaaaagca tagacaaggc tgggcgcagt ggctcacgcc tgtaatccca 167580
          gcactttgga aggccaagct ggatcacatg aggtcaggag tttgagacca gcctggccaa 167640
          catggtgaaa ccccgtctct accaaaaata caaaaattaa ccaggtgtgg tggcacacat 167700
          ctgtaatccc agctacttga gaggctgagg caggagaatc acctgaacct gggaggcaga 167760
          ggttgcagtg agccgagatc gaaccactgc actccagcct ggatgacaga gcaatactgt 167820
          gtctcaaaaa aaaaaaagat agacaatagt tcaatgtaag aaaataatta gaaagtgatg 167880
          agtttgtagt atttattgcc catttaaaat ataatttatt taattataag tttacttagt 167940
          ttaaaatgta atagtggctg tgtttaacca tcgacctgtg aaattcctgc aaatgccacc 168000
          atcagtgggt actggccggc tcagctcact cctggtggaa gggcacggag aggcctgcag 168060
          aggttagttg gtagtgggag ggggagtgta gagaaggcaa agggggcagg tgtccaggag 168120
          aggccctggt tagtggccag tatggagagg gtggccaggc ataagaagac tagacagacc 168180
          gggtgcaggg gctcacgcct tgaatcccag cactttggga ggccgaggtg ggtggatctc 168240
          ttgagcccag gagtttgaca ccagcctgga caacatggca aaatctcatc tctacaaaaa 168300
          tacaaaaatt agccaggcat ggtggggtgc acctgcagtc ccaactactc tggggactga 168360
          agtgggagga ttgtttgagc tcgagaggtt gacgctgcag tgagccgaga ccacgtcact 168420
          gcactccagc ctgggcaaca cagcaagatc ctgtctcaaa aaaaaaaatt ttaaaaaaag 168480
          aaggctagcc gggtaggttg ggaggtatta agaggacctc agtgcccatc aagagtcttt 168540
          actcagtgga cggtgggagc tcatgcaggg gtgtgcctaa gcctggtggg tgcctgtgcc 168600
          ccttgctcat cctgccgtat ctccccggcc tctcatcttc caggccatgc cttgagctta 168660
          tctggaacct ccacccttag caggaagaag ggtgagcaat gggtgggtgc tgggagaatg 168720
          ctgggagggc ctgagagcac tgcggggtgc taggcagagg cacccttctc tgccccactt 168780
          gcctcagccc ttcccgcatg atgttccatg ctgcctctgg aggggtgagg ctgggagggg 168840
          agggtatggt ggggtgggag aggccctggt cccccacccg cagaagagaa gcaggagccc 168900
          tcgatgatca cagccctggg atagacacag tgcctcagcc aagggtcagg tacatgcccc 168960
          tctggaggac aggctgtacc cctcggagac tcattgcatt ggcagctggt ctaggatgtg 169020
          ggacagtctg cggtaaggtg agtggccggg gttttagtgt gtgagatgtg caacgccatt 169080
          ttcacctgca tctgagtttc cagcagctcg cagggtaccg gccatattgt ttctctatct 169140
          gggtgctgat ctcatggggt gtttgtcttg tgaccattca ctgggctgtc caggtgcaat 169200
          ctgtgcacct ttctctgtgg ttctatgcct cacacagggt gtgcagggca cagcatccgc 169260
          agggtgtcct gggcagagga gaggggcttc tggccgcacc aggggagaag gcacagggac 169320
          ctctggcagc ccagccctca ggacacagtc aggccacgtg accttccccc caagtgaggc 169380
          gcccctggac ccacagggtt gggtgtgggg ctgctctgac ggcagccagt cccacggggc 169440
          ctctgagtca cagcctcagc ccacctgtgc cttggagtca ctcctgacag ccccacccac 169500
          cagctctgtg tgataaggga caggtccctg ctccccggct ctgctgaggg aggcgcccca 169560
          cccgagcctt cccctctgtc ctctacatga cacccctgcg gtggtaacct aactgtgtct 169620
          taaaaacaag cacttgtccc ctttccaagt cctgggtcca cattcacgca tttgcctttc 169680
          aaaggcacag ctgggctcta gtcctcgctc accacagagg aaacacaggg aagcccagag 169740
          aagccaaggt cgcaccgtcg cccagcgaag gcagagctgg ggccaagccc tggccttcgc 169800
          actccatgtg gccactttat ctctgcccag cacaggagct gcaaggaaaa gactccagga 169860
          gaggagccct gaggggacag tgccccagcc cacccatgtc cagtgagtgg gcagggcagg 169920
          tggggctgcg gaccccaggc tcaagacctt ctcaccagcc atcttcagag gagaagccag 169980
          ccctgcctca ccgcaggact acgcgcttct gcccactatg caagtgtggc gaagcctgca 170040
          gcagctgcag ccaggagctg atgggccggg gcagtgcccc attctcctgc gacagctgag 170100
          ctcccacccc agattccctg ctcccaccag gggcttcccc acagcaagga ccaccttcct 170160
          cctctgagcc agccaggcgg ccactggccc agtctggctg gggacagggc cctgggtggt 170220
          ctctgtcccc accctgcctg ttccttctct tgggctgagc ccagtgctgg ggtcaaggat 170280
          ggggaatggg tgctcttgaa ctgctgactc actgatccca atcaacagga gtttgcaggg 170340
          gaaaggtgag cccttcccac ctggggaagg cgtgtcttac tctccaagta ggcatttcat 170400
          ggcaccaggc agatgcttgg gcatttgcca tagtgtaact gttcagaaca gttgctctca 170460
          gttgaacaaa tatttccaga gcatccactg aggggcagac caggtgttgg ggccaggatg 170520
          agtaaaacac cattctccgt ctctgaggcc aggcgatctg gcaggctaga cagggctgaa 170580
          cacaccttgg gtaccatgcg tgagggccac aggacgggag aggtcctgag ccagcaccag 170640
          gcgcatgggt tagggtccag ccatcagctg gaagggtctc ctgtggaggt gataacaggg 170700
          gcttgaagag tgagccaagg gggctggcac tagcaatgcc agagcaatga ggggcaggcc 170760
          gtggggagac ggacgtagtt catcctgcca agagtgagct gcaggggcca gggtagatgt 170820
          gggggagttg tgggcaaggt gggccaggac cttggggaga acccacagtc ctgtggaggc 170880
          gctgtctggg agcccttggt gagggcggag ctgagcagga gcagggcttg cagaagagac 170940
          ctggagggtg atgtcacagg agccagggag gaaggggact gggcttgaga ggcttgaggg 171000
          catttgggag attccttggc aggggcttgg tgatggcttg ggcgtgggaa gtgaaggaga 171060
          gggaggaacc tgggaagatc cccggcttct gggcgagggg gtggtggtga ttctgcctgc 171120
          agagaagggg tggggagcct gggagggcct ggagggaggg aggagtccac agttcacact 171180
          aggacgcctg ggttttccag tggctatctg acatccggga ggaggccaga gcccagcaca 171240
          cggaggctct agagattcca agacgatgag gaggctggtc ctgagctgac ctgagcggaa 171300
          ggggcctgag ggtgcagagg gaggacgggg ctgacagcag agtcctggga gcatctttag 171360
          aggccgtgga ccacagccaa gccagtaggg agcccatcca gggaggcagt gggtacaaaa 171420
          acagaagaaa gctgaaaaga gcaccctggg actccgatat tcaaggacca ttgttttaag 171480
          gtttctgatc tccgcattca acagtgacaa gggcagcaga catcggtact ctcaggcatt 171540
          tgtacagcac cttctgcact tcaaaatgcc ttccctgcac ccccaacaca gggcttgcaa 171600
          atacaaagcc aggtgaggaa tggccctagg gcccccgtcc cagccctccc cagtttgcat 171660
          tcatttggtt cctgagctag gacgctccct ccagctaccg gcatctggct gctgaggtgg 171720
          gggccggggg cctgccagcc tgctgtgtcc ttgcccatca attttaccac ctgcgagacg 171780
          ccaggagagg gcacatgaaa tataaaatga gttgaggcat aaaagtgttt cggaataaaa 171840
          atgatgtgta ctggcaagag attacagtta ttacaaggac cgtgcgctgc cgccatcact 171900
          catacctggg agaggaagag tgtggtcgcc tgccgaagga ggcagcagcc accgtgcctc 171960
          ctcctctggg gacagggccg cagactgcag ggtgccaggc tgcaggatgg gctgaagcca 172020
          gccctccggg agcatccagt gctctggggg atgaatgaca ctcccatgtc acagttaggc 172080
          acaatgcagg gccgggcgcc gtggctcatg cctgtaatcc cagcactttg ggaggccgag 172140
          gcgggtggat cacctgaggt caggagttca agaccggcct ggtcaacatg gcaaaactct 172200
          gtctctacta aacacacaaa aattagctgg gcatggtggc aggcgcctgt aatcccagct 172260
          acttgggagg ccgaggcagg agactcactt gaacctggga ggcagaggtt acagtgagct 172320
          gagatcacgc cactgcactc cagccgggca tcacagtgag cctctgtctc aaaaacaaac 172380
          aaacaacaaa caaaaactat taggcatggt gcaaatatgc tcctttttct gttacatttt 172440
          ccaaggtgtc ttggacgttt accagacggc tttggcaggt ggcattcttt tttttttgag 172500
          acgaagtctc actcttttcc cacaggctgg agtgcagtgg cgtgatcttg gctcactgca 172560
          acctccacct cctgggttca agtgattctc ctgcctcagc ctcctgagta gctgggatta 172620
          caggtgccca ccactgtacc aggcgaattt ttgtattttt agtacagacg gggtttcacc 172680
          atgttagtca ggctggtttc aaactcctga cctcaggtga tccgcccacc ttggcctccc 172740
          aaagtgctgg gattacaggc gtgagccacc gcgcccagcc ggcaggtggc attcttatgt 172800
          ttgattctgc ccattctgca gaggagtcaa gcaaggctca ctgtatgtta gtgccttggc 172860
          ctaagtagca atattaattc tagtactgcg agtctagcct tctgaattcc attcattcat 172920
          tcattcattc attcgttcat tcattggatg aacattcttc caggcctact atgtgccagg 172980
          aactctccca gatggtagag acacaaagat gtttccagct aattattatt attatttttt 173040
          taagacaggg tctcactctg ttgtccaggc tggagtgcag tggcacaatc tcggttcact 173100
          gcagccttga cctcctgggc tcaagcaatc ctcccacctc agccccctga gtagctggga 173160
          ctacaggcgc atgccaccac acccagctag cttttgtatt ttttgtagag acagggtttt 173220
          gctatgttgc ccaggctggt ctcgaactcc tgggctcatg tccctatttt tttttttaag 173280
          ttgatggata gaattttctt ggttttaagt ttctctttca tgcactttta ttaaaacatt 173340
          ggcatctgtt atccgtaact acattaagat ccctctaaga tagtatctgg ctgggcccag 173400
          agtaccaaca ttgaatgacc tgtggtttcc tagggcagga tttcgtggga ttttgcagag 173460
          agacccctca ccccggctct gggccaccct gaataacaat gtcaaaaacg atctggtggg 173520
          caccctctgg agcagggtaa ggtgagttgg gagagaacat ggctctctgc agccagactc 173580
          agtggctcac acctgtaatc ccagcacttt gggaggccga ggtaggcgga taatgaggtc 173640
          aggagttcga gaccagcccg gccaatatgg tgaaacccca tctctactaa aaatacaaaa 173700
          ttagccgggc ttggtggtgt gtgcctgtaa tcccagctac tcgggaggct gaggcaggag 173760
          aatcacttga accagggagg cagaggttgc agtgagccaa gatcatgcca ctgcactcca 173820
          gcctgggcaa caagaggaag actccgtctt aagaaaaaaa aatggctctg tctgcaagct 173880
          caggtgtctc aacgtctggt tctaccacta ccggctgtgg ggctctgggc aagatgggaa 173940
          cgtcacacca gatggcccgg ggaggcccca ggggagtacc ctgctcacag tgagcacaca 174000
          ctccacggca gctgctgtta ctaggatgat gtgatgttgt tgtgttgttg gtaggactag 174060
          gcccatccag ggagggtctc aaagctgggt ggggagagct ggcgtgccac ttggggagca 174120
          aggagctccg tctctcagct gaggctggac gtctacctct ctgacactgc aggtgtgtgc 174180
          gccccctccc tcctggggat atcatgagga tgaagcagaa gcacgcattg tgtgtgtgca 174240
          tgtgcagggg gcagggtgaa gaaatcttac aattttaaac tgctcaggtg tctgggaagt 174300
          aaagaaaaga aggaaggaat gaagccctcc ttttgggatg tcttggggtc acagagaccc 174360
          ttttctggga agatttttca tttccccatc ttttttcatt tatttgagac agagtctcgc 174420
          tctgtagccc aggctggagt gcagtggcac gagctcagct cactgcaacc tccacctccc 174480
          aggttcaagc aattctcctg cctcagcctc ccaagtagct gggataacag gtgtgagcca 174540
          ctatgcctgg ctaatttttg tatttttagt agagacaggg tttctccatg ttggccaggc 174600
          taatctcaaa ctcctgacct caggtgatct gcctgcctcg gcctcccaaa gtgctgggat 174660
          tacaggcgtg agctgcagcg cccggactcc gcacctattt tctgctctgc gtagggacag 174720
          cctaatgcat tctgcagcag ggagccatgg caaattggta acaagccggc ccctggcctt 174780
          catcccaccc ctccccgttc tcagacctgc cctgtcagct gacagtcctt tgagccagtc 174840
          tcagctcaca gcttggcctt ggcagtgatc atcccaggct ctgagaaggg ctggcccctg 174900
          ctagtctcgc aggaaggacc ctgctggctg tgtgtggtgt gcgccgcgct cactgacccc 174960
          tccgggcccc ctccttccac ctcccttgct gcccttccga cgggtgagcg gggagagcaa 175020
          ggcatgagcc cccagcgcgt tctagtcctt cctgcgtggc tgtttcctga gtgctgccca 175080
          ctcagcatgc actacccccc caggccagga tgatgctggg cacaccaggg aagcagggag 175140
          agaacctgtc cttgcctttg tgaaggggga atcgtcgtaa gcagggaatg attgcaacgt 175200
          atgagagact gtggcatgga ttgtacctgt cacctctcgg cctcaccttt ctgagcctct 175260
          gtcggccctc aggtctatgc agactgcgcc tctccctccc cctcaccagg cagccaagca 175320
          gccccttgct tcttcgtctg ccctggggcc tcttggacct cacctgcagg acgtgctctg 175380
          cacagtttcc tgcacacctg caagtgtgtg ggggcctatg cctgtgagcc acccttgagc 175440
          aaaggtgtaa agaccgaagg acaaggcccc ccaggcccct gcaagtgggt ggttcatgag 175500
          cttccttgga aggtcccaaa ggacggagct ccagccaccc cagcagtagc cagctccatg 175560
          acccccgttc ccttccactc ctgtgtcact ccctatccct caggggaatg cagctaaagc 175620
          agcagtgtct ggggagcacc cagcagggcc gtgactcagg ctggggatca gggagggact 175680
          ccctgcagag gtgacattta agccaagctc tgaagcagga atgggagttg tccgggcaaa 175740
          gaggcatcct gggtgaggaa agcagcctgt gcaaggcctc gaggtaggtg aagctgcttg 175800
          ggagtagcaa cggcagggtg ggaggagtag gcagtggaga ggatggacac ggtggagggg 175860
          agggatgtgg tggagaggga tggacacagt ggagaggagg tacatggtgg agaggatgga 175920
          cgtggtggag gggagggacg cggtggagag gatggacgca gtggagagga gggacatggt 175980
          ggagaggatg gacgtggtgg aggggaggga cgcggtggag agggatggac gtggtggagg 176040
          ggagggacac agtggaaagg atggacacag tggagaggag ggacatggtg gagaggatgg 176100
          acgtggtgga ggggagggac acagtggaaa ggatggacgc agtggagagg agggacatgg 176160
          tggagaggat ggacgtggtg gaggggaggg acacggtgga gaggatggac gcagtggaga 176220
          ggagggacat ggtggagagg atggacgtgg tggaggggag ggacgcggtg gagaggatgg 176280
          acgcagtgga gaggaggtac atggtggaga ggatggacgt ggtggagggg agggacgcgg 176340
          tggagaggat ggacgcagtg gagaggaggt acatggtgga gaggatggac gtggtggagg 176400
          ggagggacgc ggtggagagg atggacgcag tggagaggag ggacatggtg gagaggatgg 176460
          acgtggtgga ggggagggac gcggtggaga ggatggacgc agtggagagg agggacatgg 176520
          tggagaggat ggacgtggtg gaggggaggg acgcggtgga gagggatgga cgtggtggag 176580
          gggagggaca cagtggaaag gatggacaca gtggagagga gggacatggt ggagaggatg 176640
          gacgtggtgg aggggaggga cacagtggaa aggatggacg cagtggagag gagggacatg 176700
          gtggagagga tggacgtggt ggaggggagg gacacggtgg agaggatgga cgcagtggag 176760
          aggagggaca tggtggagag gatggacgtg gtggagggga gggatgcggt ggagaggatg 176820
          gacacagtgg aggggaggga agtggtggag aggagggacg tggtggaggg gagggatgtg 176880
          gtggagagga tggacatggt ggaggggagg gaagtggtgg agaggatgga cgtggtggag 176940
          gggagggaca cggtggagag ggatggacac agtggagagg agggacatgg tggagaggat 177000
          ggacgtggtg gaggggaggg acacggtgga gaggatggac gcagtggaga ggagggacat 177060
          ggtggagagg atggacgtgg tggaggggag ggacgcggtg gagaggatgg acacagtgga 177120
          ggggagggaa gtggtggaga ggagggacgt ggtggagggg agggatgtgg tggagaggat 177180
          ggacatggtg gaggggaggg aagtggtgga gaggatggac gtggtggagg ggagggacac 177240
          ggtggagagg gatggacaca gtggagggga gggacgcagt ggagaggatg gacatggtgg 177300
          aggggaggga tacggtggag gggagggagg agaggggagg gacgcggtgg agaggatgga 177360
          cacagtggag gggagggaca cagtggagag gatggacacg gtggagggga gggaagtggt 177420
          ggagaggagg gacgtggtgg aggggaggga tgtggcggag aggatggacg tggtggaggg 177480
          gagggacacg gtggagaggg atggacacag tggaggggag ggacgcagtg gagaggatgg 177540
          acatggtgga ggggagggat acggtggagg ggagggagga gaggggaggg acgcggtgga 177600
          gaggatggac acagtggagg ggagggacgc ggtggagagg atggacacag tggaggggag 177660
          ggaagtggtg gagaggaggg acgtggtgga ggggagggat gtggcggaga ggatggacgt 177720
          ggtggagggg agggacacgg tggagaggga tggacacagt ggaggggagg gacgcagtgg 177780
          agaggatgga catggtggag gggagggata cggtggaggg gagggaggag aggggaggga 177840
          cgcggtggag aggatggaca cagtggaggg gagggacaca gtggagagga tggacacggt 177900
          ggaggggagg gacgcggtgg aggggaggga cgcggtggag gggagggagg agaggggaag 177960
          gatgcggtgg agaggaatgg atgtggtgga ggggaggaac gcattggaga agatggacac 178020
          agtggagggg agggacgcag tggagagaga cggatgcatt agagagggat ggacgtggtg 178080
          gagaagatga gcgtggtgga cagggatgga taagatgctc agcaatggac gcagtggtca 178140
          tcggcgcctt cttggcaggc cacagggagg agtttagact gcgctagggc aagggggagc 178200
          cacacaaggg tttggagcag gaactatttt ggccacttga tggagaccgg atgcagtgtt 178260
          ggggccagag caggcaggga gacccattag gaggctgttc cggtgacccg gtaggacgac 178320
          aagcaagaac aacagtgggg gtggggagaa tacccccaaa ttgtgccata gtcagcttca 178380
          gcatctcatt ccgtgtgaat tacgaggctg gtcatggtga gtgtcggggc ctccatggat 178440
          gctcggggtg atttctcatg gatcctgcaa ccacgtctcc ccttcacaag cctcttgcca 178500
          agccctgctg gccctggtcc tctgtgttct tgctccttag gtcagtctca gacattcctg 178560
          acacttgtgc ttcgtggccc tttcccagcc ctggctggca tctcgcgatg tagaagggag 178620
          agaggccaga aggagagcag ctcagcccac gaggaggtgc ccatggaggc tggcaggggc 178680
          ccaggggccc ccctgcactc tccccagttt tgagacctta gggcagtctc tcaccctcca 178740
          gtcttggttt ctccacctct gaaagaatca cttttccttc ctgccaggaa ctgaagtcaa 178800
          aggcacggca ttattgagac acattgggga gcagtgggcc cagcactggg acccatgctg 178860
          ggtgtcccaa gagcacagaa tgttggcagg gaggggcggg ggccaggcag ggagctccct 178920
          gctgctctac ggctgcccca cctgcagccc ttcccttcac cccacgcccc agtttcctct 178980
          gctcttgggt ggccagtcac ccaggggtgg tatccaggga ggttcttgca ggcccagctt 179040
          cactggcctg gaagggctaa gctacctggc ccaggggtgt gtccactttg tcctgggcag 179100
          gctatgggca tcccacaggt ggagtcccat ggcagggctg gagccagggg gtaactcggc 179160
          aggacagagg cccagccacc aggaagctcg cctgctgatg gccaagctca ggacaccttg 179220
          caccactgta cctgaggaca ggctgtgact gatgacagtg gcttcatcct cagaggggaa 179280
          gtgtcctgga gggatgtggc tggaggcacc cagccctgcg ggagcccctt tgaatgagca 179340
          gatacctcgg gaagcagggt gaagggggca gaaactggga actctggatt tcaagacttg 179400
          aaagaaaagt gctgcattgt gcggtggcat ctgcttgtgg ggacaagggc tccctggtga 179460
          gacctctcca tcccctccct ccctccccct ctgtctcaca ctctttctct ctctccctgt 179520
          cctcctatct cggcctcgca ctcgggtcgt gtttggtctg tgatgtcacc actcccctcc 179580
          ctgtggctgc cattcagagc tggcagtaat gaaaagcaca ggattcccac tcactgggcc 179640
          ccagcagcac tacagagaca tggagccctt tgttgcaaat aattaacttg gtcccatgtt 179700
          gcataacatc ctaaaaagct ttcctgagcg agcacccgcc agacactgtg atctcatcaa 179760
          tactgcatcg catcggacac tactgctgtg tgatttcatt aaaaatttaa tttgtgtttt 179820
          aaatctgcag tgttcccttt aaaaggatgg cgagggcggg ggatgaagag agtgacaggc 179880
          ttgggtctgg gggtgggcat tccaaagcag aggaaacccc acgccccaca ggaggtgggg 179940
          gcggggcttc ccactggagc agcggcccct ctccgattgg ctgggcttgg tctgtggcct 180000
          ctcctggtgc tggagggaga gtgatggacc attgatggaa aatgcttttc tgaagcttaa 180060
          tggttttccc tttctctcgg ccacctcagg cagagggctg ctcctgggaa cccagacaca 180120
          ggaggatggc caggtggtgg tgcaggtggt ggtgcaggtg gcggtgcagg tggcagggca 180180
          ggtggcggtg caggtggcgg ggcaggtggt ggtgcaggtg gcggtgcagg tggtggggca 180240
          gggcaggagt gccaggtggc agggcaggtg gcggtgcagg tggcggtgca tgtggtgggg 180300
          caggtggtgg ggcagggcag gagtgccagg tggcagggca ggtggcggtg caggtggcgg 180360
          gggcaggtgg cggtgcaggt ggcagggcag gtggtgcagg tggtggtgca ggtggcaggg 180420
          caggtggcgg tgcaggtggc ggggcaggtg gcggtgcagg tggcggtgca ggtggtgggg 180480
          caggtggtgg tgcaggtggc ggtgcaggtg gtggggcagg gcaggagggc caggtggtgg 180540
          gcaggcggtg atgcaggtgg tggtgcaggt ggtggtgcag gtggcagtgc aggtggtggg 180600
          gcagggcagg agggccaggt ggtggtgcag gtggcagtgc aggacgtgtt ttccggagac 180660
          cccgtcctct gtgcccctcc agacccagtg cctacagtgg tcaagaccag agctgcagcc 180720
          tcactcctgc cctcctggct gtgtgacctc aggcaagctg cttgtcctct ctgagtacag 180780
          atcactgccc ggagtgtgag tgggggcctt gcctgtcccc agctccaggt tgctgacagg 180840
          agagtgtgag tgaagggcct tgcctgtccc cagctccagg tcagcacccg cagtgtcact 180900
          ctcacccccg tgtggctatg gagcaggcag ccattggtga ctgggtagca gaccctccgg 180960
          aaaggctgcg gttctgtttt ctttctttgt ctagacttca ctctcttcca gagaggattt 181020
          aagctggcct tcatcatcgg tgctgcctgc agacccgtcc ctgggatttc gctgcgaatg 181080
          ggatcctgtt gtttctagac agggacctcc attgtgttgg ggggggattg gtttcactcc 181140
          tgtttccagt gagcggggag ggaaagagag ctcaggttct ggttggggga ggagagagag 181200
          gaaggtgagg ggagcacgga gaaggagact ctggggcaac ttcgtgatgc tgcctgcctg 181260
          gctctgcctg gggactcttt ggtcccgccc gccctggcca ggccaattgt ttcctgcgga 181320
          aggcagggat ttgtgcatct ccaactatct cctgacagta tgccagagtg attaagctaa 181380
          gcctcccggg gccagcagaa gagaggggac aaattgcttt gtgaaattga tttgctgctg 181440
          ttagcattta cagcttgccc tgggtacgcc cacagtgtga ggcggctgcg tgggcgtcct 181500
          gctccccctt ccctctcccg cagcacacgg gctctcactt ggcacctgcg cacacatcac 181560
          ctgtcgtgtg tcacatagcc aggcctcagg acctggactt cagtaccact cacctcaggg 181620
          cacaggtcca aagtgtccca aatgcccatg gaggcagacg gccacccaca gctgcagcct 181680
          gcagagagaa ttgccccaga gactcttgga taggtgggtt tccccaggcc agcgtgagag 181740
          ctggggccac gagatctgag aggacacctg gaggcccaga gaggaggcgt gagctagccc 181800
          tgggccaggg tctccccatc tctttttttt aaatttgttt tgttttagac tgagtcccaa 181860
          tctgtggccc aggctggagt tcagtggcgt gatctcggct cactgcaacc tcctgcctca 181920
          gcctcccgag tagctcggat tacaggcgca tgccaccatg cccggctaat ttttgcattt 181980
          ttagtaaaca ctaaaaatga tttcatcatg ttggccaggc tggtctcgaa ctcctgacct 182040
          caagtgatcc gcccgtctca gcctcccaaa gtgctgggat tacaggcgtg agccactgtg 182100
          tccggcctct ccccacctct tggggggccc cttctgccac accggctgcc ctcctccatt 182160
          ccaggggaag gaagacaagg agaatattgc cctggtcagc aacagttctc atagaagctg 182220
          tatgaactca ggtgagcgtc atgaacccac acgcctgggt gctggggcca ttcagagaag 182280
          aggcggtgct gggactggtg gatccttcca gacagagaaa tgtggctgag catcaccacc 182340
          caggaaatag aaagcactga caattcgccc aggtgggtcc cactatgcat ttcaagaaat 182400
          gcgtgcttgg taacggaggc agcatggcct cggtgcaccc caggagatgg gagactcagg 182460
          ctacgggcgc tgctgggtat agtagcctgc tttcaggctc tccttgggca ccagctctga 182520
          gcaggctcta ggcatgacta gatggtggga agggggtcca gggagccatg agaggagcag 182580
          cctcagcgtc tctcctgggc tggagccagg tccatcgctc agctgctgtg taacctcaga 182640
          caggtgactt cacctctctg ggctgtggta agggttacat tagacaaacc ccacaaggct 182700
          cttagaacag tgccggttgg taggcggggc acggtgactc acacctgaaa tcccagcact 182760
          ctgggaggcc aaggtaggcg gatcacctga ggtcaggagt tcaagaccag cctggccaac 182820
          atggtgaaac cccttctcta caaaaatcag ccgggagtgg tggcacacac ctgtaatctc 182880
          agctactcag gaggctgagg caggagaatc acttgaacct gggaggtgga ggttgcagtg 182940
          agctgagatc acgccattgc actccagcct gggcaacaga gcacggactc cgtctcaaaa 183000
          aaaaaaagaa cagtgctggt cagtggaagc atttggcaaa tcctagttgt gactgttgct 183060
          gttttcccct cccttgagat gctcagatgt ttgtcatcat acaaggacgt gagggtgggg 183120
          cacaccagca gtgcttctga ggttaggggg ctcttcagtc ccaggccagg gggaaggaag 183180
          gaaagtgggt ctctcagcag caccacagac tggaccctag cacagcaggc acgtcccttt 183240
          aaaaatttaa attaaaaata tttaaatggg ggtaaaatat acataacata aaatgtacca 183300
          tgttaactgt ttttgagtgg agcgttcagt ggcattaagc acattcacgt gattgtggga 183360
          ccatcaccat gagtccccag aactcttttc atcctcccaa actgaactcc gtctccatta 183420
          aataccaact ccccattcgc cctcccccag gcctgggcac ccccccattc tacctctgtt 183480
          ccagttaaac cagtgcccag cgagactcat gtaagtggaa tgatacagtg tttggcccag 183540
          gaagccttgt gtaagtggaa tgatacagtt ttgacccaag gaggctggtg tagcttctac 183600
          ctttcctcta taatgaataa gactgctgtg aacacgggtg tagaaatagc tcttcaagac 183660
          catgctttta cttcttgtag atgtgtaccc aaaagtggaa ttgctggatc atatacctcc 183720
          cttttaaaac aaatgcagaa actgaggcta tacagaaggg ctcagaggtt tgccgagggt 183780
          cccagccacc tcagtggcgg agcaggcagc atttccccac cccaactctg tgggtcgctg 183840
          gcactatgct ctccctcccc agcgtctgtg tggcctgttt tattcccagg ctttatagaa 183900
          ggctctctgg aagacatgag ctgtgatgga tgcaccaaag gagggtcatc accattcctt 183960
          cttttttttt tttttttttt ttctggagac aaagtctcac tctgtcaccc aggctggagt 184020
          gcagtggcgt gatctcagct cactgcaacc tccgcctcct gggttcaagt gattctcctg 184080
          ccttggcctc ctgagtagct gggattacag gcacccacca ccacgctcag ctaatttttt 184140
          gtatttttag tagagatggg gtttcaccat gttggtcagg ctggtctcga actcctgacc 184200
          tcaaatgatc cacccatctt gtctttccaa agtgctagga ctacaggcat gagccaccat 184260
          gcccagctga gtgtcatcac cattctgaac tagttttact cacactctga caccaaatgt 184320
          gtgagggttt tttttttttt tcctacatcg accagttctt caactttcca gacagctggg 184380
          tggcctacaa ctcacttcaa ttcttacact gactacctgt agttagcaca gacctcacat 184440
          ttaagggtca gtcccacaag attgccccct ccttcagaca ccaatgacaa gtcccaggtt 184500
          gtcaccagtt cttctggttg actggctata aatcagggtt cccataaccc ccatctcagg 184560
          ttcaacagtt tactagaatg actcacagag ctcaagaaag tgctttactt actattgctg 184620
          gtttattata agggctacaa ctcagaaaca gccacaaaga agagatgcat aggacaagat 184680
          acgggggaag aggcaccaag cttccatgcc ctccccagca ccttgacctg ttccccaacc 184740
          cagaagctct ttgaacccca tgtttagggc tttttacgga ggctgcatca cacagtcgtg 184800
          cttgattaaa tcatccgcag ttggtgatca actcaatctc cagcccctcg cccctgtcca 184860
          gagctcattg aatcgggagc cttaagaacc ccccaccccc agttgctctt tctcttccct 184920
          ctggcatggt ggctagatcc ctaggtgatg aagtggaagg aggcctcctg ctgatccacg 184980
          atgaacctac tgtgggaaag aaccagaaag aacagctgcc gcttagagca ggtggtatct 185040
          caagcctgtg tgttactgca gcaaaaccta tggccgcctg ggtcctgacc acctgagggg 185100
          tacagtgttc tcaggggcgc atttctgcct tcacgtccct gagcctgggg aagtcctgcc 185160
          caaactcggt tctcctggag tctctttcat ctttgaggca accactacct ttccgtcaac 185220
          tccctcttct gcttcagtta accacaggta ggttttgctc cttgcaactg acaacctggg 185280
          ctgatggagg aagctgtttc agctgttatc aagcaacacc tcgagcaggt gagtctgtag 185340
          ctggaggcct ccaaggtgct ggtgtctgaa gcaaagatag gtcactggaa aaagaggtgg 185400
          cgtgtgtgtg tgtgtgttta gaaacagagt gtagttgtgt gtctgtgcat gtagaaagag 185460
          gacatggttg tgtgtgtgtg tttgtgtgtg cgtgtataga aagaggatgt ggggccaggc 185520
          acagtggctc atgcctgtaa tcctagtgta taattgggag gctgaggtgg acagactgct 185580
          tgagcccagg agttcaagac cagcctaggc aacatatcga gagtctgtct ctacaacaaa 185640
          aaataaaaaa ttagctgggc atggtgatgc atgcctatag tcccagttac tcaggagact 185700
          gaggcaggag gatcacttga gacaggaagg ttgaagctgc agtgagctat gatcacgaca 185760
          ctgcactggg taacagtaaa actccgtctc aaaaaaaaaa agtgtttttt tgtgtttgtg 185820
          agcatgtgtg tgagtgtata ggaagaggat gtggtcatgt gagtgtgcct gtgagtaatg 185880
          tatatgtgag tatacctgtg tgtgtgtgtt gtgtgtatat gtgagtgtgc ctgtgtgtgt 185940
          gtgttgtgtg tatatgtatg tgttgtatgt atatgtgagt gtgcctctgt gtgtgtgttg 186000
          tgtatatgtg agtgtgtgtg ttgtgtgtat atgtgtgtgt tgtgtgtata tgtgagtgtg 186060
          tgctggggca gcatcacagg aattcgcctg ccataaggcc gggctgcgtc acggctaagg 186120
          ccgcagttcc cccaccgtgc ctgggtttgg atcctggctg ctccggtcgc ctgctgtggg 186180
          tccttgcaca cattaacctc tgaacaccag tggccgtatc tgaaatagcg cgagaacaaa 186240
          actcaggatt gctggggagc tgtaggagtg gaattatgca aagcatggca tgtcgcccgt 186300
          aacagacttc cgggccaccg tggtggtgcc gacacaggcc ggccggggcg tgcgtggggt 186360
          ctggctttgt cttcttgtct ccctctgctc ctccctcctc ccctggccga gggagcccgg 186420
          cctgtcttcc tggccacagt tcgggaggcc gccgtcctca aagctgggca ccagctatgg 186480
          ctcagtgtct ccagcctcca ggattcctgt ggtcgggatc cagcgtctct ttatcgtttt 186540
          taaagtgttt tgctgctggg aagcctcaag cctctccgca gagggacata aataaaggca 186600
          ggaacttggc cattagtagg cttcatgtgg cgtttccacc tgggagcgcc ctggcgtgct 186660
          gcaagctgcc ctcactggcc aagagcaggg cgggagggga gcctctggag ttctccggtt 186720
          ctgggttagg tgcctcttac tctctgggct gcaaacagac gggggtgcct ggcaatgtgc 186780
          cccgggcgga gcacccctaa cagttgcagt tcaaatttgg agccaggctg accctggttc 186840
          aagtcctgtt gctgtgtgct ggccgtgtcc ctggacgggt ggcacaaggt cttggtctcc 186900
          agtgtgcaga tgagagatgg tgattatcta ctcctgggtg ctgggctcag agccgctggc 186960
          accagccctg ggggctgcca gacatatagc cctcggctct gtcacgcccg gaactcaaac 187020
          ctcgcaggca gtcaggggag aggtctgtgt gtggagctca gaactcagtg agcaccccat 187080
          gtgcctgtaa ggcctcgcca tctcctaccc aacccagatg aggctcctgc ttcccacccc 187140
          tggcagggag tctgatctca tcctagctca aaggtggaaa ctgaacgtgg gccaggtggc 187200
          aaagttcccc agtgggttca gcttccgccg ggtggaggag gtgggaggca tggctggagg 187260
          cctggcatca ggctggatga ggtggacccc tcaggcttga atccaagagg gctcagaggg 187320
          tgagtggggc cccaggccac gtctccaaca gctgcccacc tagccttgcg cctccgcctt 187380
          ccttccttcc tttaaaaatg gctacaggca cattttcttt gattactttt atactgaata 187440
          acactatcct ttttaaagca aaaaatacat gctcatgata aacaaatgga accggacaga 187500
          tctttatcaa ggcccccgca atgtgacctt gtgactccaa gacagaataa ctttccatgt 187560
          gtgttttcaa gaggttgtgg ggagccgctg aacctgggag cagtgagggc acaggcgaga 187620
          gctgtggcca ggagagtcac aggagcggca aagacgaaag ggagtgggag atgggaggcc 187680
          aatcagaaag cagtgcccga agctgggtga ggagcagcaa aggcgggggt ttccttgagg 187740
          atacctgaga gccatgctag ggtggggagg tctgggggga gttgtgggct ggccttgagt 187800
          ttgagattga ggcccaggct gagagcgtgg tgacccctgc actgtgggtc tgctcgagct 187860
          gtgtgcttcc caggagcaag agcaaagagg ccagagggag gggggcagaa caggccagca 187920
          agggagcccc cagaacagga cacgcgttcc ttggccctcc ccaggcagcc ctaagaggga 187980
          agagaagctc tgccccctcc tgccccctcc tgccctctcc tgttccctcc tgccccctcc 188040
          tgctctcctc catggagtca gggggcccca ggtggccatg gccagcccat tcagggatct 188100
          gagccccaga gcctgcatgc cagggtgagc agagccagct tgactgcagc catgctgacc 188160
          ccgcaacctt ccccgaggtc tgaggacacc acgctccctt cctgccggca ggttgtaatt 188220
          gggtttcaca cggggccttc tggcgctgac ctacatgttc cggtccgtgc ctccttggtt 188280
          tctgagtgtg tgcccctgat ggttctggaa cctctgggcg tgggcctcct tccctccccg 188340
          cctcatcagc tgctctgatt ccaccgggca aggtcaggct ggcaaggaag gaattggagc 188400
          tgcagtctgg gcgccaggcc cagagtgtgc ttcccagggg ctgcctgtgg ggaggctccc 188460
          gatctgccca ctcccgaaat aagaaggggc gcccagagag gaggagactc tggatgcgtg 188520
          gtcagcaggc accggctgcc atccccagga gagtcattgc ctgtgaggac gttgaccctg 188580
          gtaggacccg cctctctgaa gctgtctcgg gtgtgagtga ggaggaacgg ggtctctggg 188640
          gactgagccc tcatctccag tgcaaaatgc agaggcatgg gagggaatca aatgaaacag 188700
          tgtgtgtgga acagaaggcg ccaaatggga atgtccccct gcctgtccat ctccctccct 188760
          cccccgcctc cttatttgca gacggaggga ctggatatcc tggcagagcg tcttccgtga 188820
          tgcgtaacct cccaggagat gcatgttctg gggttcccca cttacagttg agaatacaga 188880
          ggctaagaag ggtgaaggga ctgcctccgg gtcccaaggc tgttccaagt gatctaggac 188940
          tcagctttgg tcctcctgcc ctcagcaccc ttggtcatca cctccactcg gtgtgcagga 189000
          ggctcctgct gtaggtgccc agatgttcgg cagctttgta cttagaaatt tcgagggggc 189060
          ggtcgggcgc tgtgtctcac gcctgtaatc ccagcacttt gggaggccga ggcaggtgga 189120
          tcacaaggtc aggagatcga gaccatcctg gttaacacag tgaaaccccg tctctactaa 189180
          agatacaaaa aaatagccgg gtgtggtggt gggcgcctgt agtcccagct actcgggagg 189240
          ctgaggcagg agaatggtgt gaacccggga ggcggagctt gcagctagcc gagatcacgc 189300
          actgcactcc agcctgggtg acagagcaag actccctctc aaaaaaaaaa caaacacaca 189360
          gaaatttcga gggggcagag ggtgtcctaa ccttgtccct cagcaggtct tcaccctggc 189420
          accttcacca gacacccgcc atggctctcg gctcagcggg tagctgagtg tgttctcttt 189480
          gggttctgac aggttccagc ttgttttttg agaccttgtc agcgtggggc ctgccgggaa 189540
          gcaggtgctt gtctttaatg ggatgcctta tcctgggctc cacaggctgc acggggcgtt 189600
          gttcaggtga ctcctacacg ccgaggcgtc tctagaggag gagcctcaaa aggactagca 189660
          gggggtgcag ataactttgt ttttaaaatg aagccaaagc tttcaccaca tctcagagac 189720
          agagtgaccc gaatgtggag gtttggctgg aaccaggcag gtaccatcca ctacggctcc 189780
          cacctctcct gctcggaatc ccccgctgcc ctcccccagg ccctggtctc tgatttcaga 189840
          ctcgcctctg ctctgtttca cgtctcctgc aagcagacaa gcatgaagcc tgccctccga 189900
          ggctgcatga ataatagaac tgaaatcatc cctagttaaa aatagatact cttcttaata 189960
          aatattttac atactgtctt taggatatac aggtcccctg gctgaagact taaagcaaac 190020
          cctgttatcg aaaccaaaag atgtaggaaa ggctctgccc gggctctgcc agtgtgttcc 190080
          tgcaccacgg ctcttgcctc aaagccaccc actctgcggt gacgtccgac gcagacagcg 190140
          cacacacgga ttacgttgga actcatagcc aggagcggct tgggaattct tgggtgtatt 190200
          agtcacttgt gaattttatg gaggcaaatc aattataaag tgccccttgg ttagtgaggc 190260
          ttggagttca gaaaacccaa aagcaggttc ttacgttact gctgcgaggc aaggccttca 190320
          ccgtgaatgg aagctggggt gtctgggggc agctgtgtgg aggaagagaa aattctgggc 190380
          agaagcagtt ggagtttaaa gtgctggccc atttctgaaa actttgcaaa ctttgcaaaa 190440
          actttggatc ggacgtcact gcagagtggg tggctttgag gcaaacagag caatcttgaa 190500
          ggtctccatt aatgaaggca tggcgtggtc tggatgcagc aaatgcattt gaatgatctg 190560
          caggaaggcc tcgtagcctt gctcccccca cccatgtgct tccccaggaa gacaggggca 190620
          gctaggaaat gctggggcct gcccagtgtg cagaccgctt ccaggtgacc ccacgctgca 190680
          tggcccaagg caaaggctgg agcgtcctta tttaacagga gaggaaagtg gatactggaa 190740
          gggcagagcg tgctggggct ggaacagaca agccccaggc tggagggccc atgtctcact 190800
          ccctctgccc cacacctcag ctggtctgcc tatgtggtat tcttgaactg agtgaagaga 190860
          cccttctctg tcagggccac ctgccccaca gaggggctct tgtcttcctt gtgctcaaca 190920
          taccttgagg acattttgct ttagcaccca gcaccctgga tggcatgtag gggtccaggt 190980
          gtgtctctgc tccagacagt gaatccttga gcacctggct tagagctggg cccctggtac 191040
          atgttgttac atggatgggt gggtaggtgg atgggtgggt gggtaggtgg atgggtaggt 191100
          gggtgatatg atttggcttt gtgtccccac ccaaatctca tcttgaattg taatccccat 191160
          aatccccacg tgtgaaggga gggacctggt aggaggtgat tggattatgg ggggtggatg 191220
          ggtggatgtg tggatggagg gatgggtgga tagatggagg gatggagggg tggatgaata 191280
          gtgtgtatgg ataagtggat ggagggatgg gtggatgggt agatggaggg atgggtggag 191340
          gggtagaggg gtggatggac ggatggatgg gagcatgtat ggataagtgg atggagggat 191400
          gggtggaggg gtagaggggt ggatggacgg atggatggga gcatgtatgg ataagtggat 191460
          ggagggatgg gtagataggt ggatggaggg atgggtggat agggggatgg agggatgggt 191520
          ggatgggtgg atacatggat ggagggatgg tggataggtg gatggatgga tagagggagg 191580
          ggtgggtgga tgatggagag agggatgagt ggatggatgg atgagtagat gaacagatgt 191640
          gtggataaag ggatgggtga atgggtggat ggagggatgg gtagatgggt agatggaagg 191700
          atggatggag gggtggaggg gtgggtggat ggatggatgg attgttgtgt gtatagataa 191760
          gtggatggag ggatgggtag atgggtggat gtgtggatgg aggatggtgg ataggtagac 191820
          ggatggatag agggaggggt ggagggatga tggagagagg aatgagtgga tggatggatg 191880
          agtggatgaa tagatgggtg gataagggga tgggtggatg gagggatggg tggatgggta 191940
          gatggaagga tggatggagg catggaggtg tgggtgggtg ggtggatggg tgtgtgtatg 192000
          gataagtgga tggagggatg ggtggatagg tggatggagg gatgagtgga tgggtggatg 192060
          tgtggatgga gggatggtgg ataggtggat agagggagga gtggatggat gatggagaga 192120
          gggatgaatg gatggatgga tgaatggatg aatatatggg tggatgaagg gatgggtgaa 192180
          tgggtggatg aatggaggga tgggtggatg gagggatgat ggatggtagg ggtagatggg 192240
          tggatggagg gatgggtgaa tgtattgatg gtagggtgaa tgaagggatg ggtggataga 192300
          tggctgggtg gaaggatggg tggattggtg gatagatagg tgaatggatt gagggatggg 192360
          cggatgatgg atggtggatg gatgggtggg taggtggatc catggatgga tgcacagagg 192420
          gaaaaaggca cattgtatca gactccaaag ggagaattaa ttgcagcata aaatgggagt 192480
          ccaggacctc tcttatttca gagttcatcg tgtagatggg aacagtgttt aacccttccc 192540
          tctcccactg ccctctgtca gctgcttccc agttcctaaa ttattggctc tgaaagtggg 192600
          ggctggggga gtggggaaaa gagtggagat gctgagactt tcccatgtgt ccagcttcca 192660
          gaggcttcca ggacagactg tggcaccatg gttagtagcc aggagcaggt tagggcatta 192720
          tggtacctcc ccaaacaaag cagggtgctc cagcttcagg cagtcaggac cccatctgct 192780
          cagtgagtgt ctggtcagca cccactcagg ccaggctgtg tggcaaatac aaaagaagtt 192840
          aaaaaaaaat aaagacattc cattatttca atagaaagaa ttttttaaaa atgtgtcact 192900
          ggaggtacac ttgctttaca ttttttgctt tggaagatgt agggaaaaaa gtcatgaaat 192960
          gttttcattt ctctgtgatt gagcagactc ttaaaatatt aaactattgc ttaataattg 193020
          attaaaacta atctctgtgg gagccaacca cccatttggt aggatctctt taaactttta 193080
          ggggctttta gctccccctg gccgcctaac ctttctcttg tctgattcat tctgggctca 193140
          gcagacgttt ggtctcttgt ggattgatga tgtcaggatg cttctgtcgg gccgtgggat 193200
          ggctgatgag gctggattcc gaacaaggaa catcctaggg acacagtgtc tggagaggca 193260
          gtgagggaag aggaaagaaa tgtctgtgaa taattgtact gcagcttcta aaactcggga 193320
          cgggagtcag agaaaacagc cctgtggcct tcagagccgc ttaagttgtc tgtgacttga 193380
          gtttttccac acaatgacaa tggtgcctgc ctctccattt tcccaggaac gctaagccat 193440
          cgagcaaagt ggtttagaat gtgggcgcag gcatccgagt gtctggcttc aaaacttccc 193500
          cagcaagtta ccgaatgtgt aaccttggac gcgcttttta ttttctctat acctcagctc 193560
          cttatcaata aaatgaggat agtaatatta atagaaaccc tcttctgtgc agatgaggtg 193620
          aggcaatgca tgtaaagttc ttagcactgg ccagggctgg gcaaaggcag ggctcactat 193680
          gcatttaaga gctcaaagcc cgggtgagct ggctcacgcc tgtaatccca gcactttggg 193740
          aggccgaggc gggcggatca cctgaggtcg ggagttcaag accagcctgg ccaacatgca 193800
          gaagccctgt ctctactaaa aatacaaaaa aattagccgg gtggggtggc acacgcctga 193860
          aatcccagct actccggagg ctgaggcagg agaatcgctt gaacccggga agcagaggtt 193920
          gcggtgagcc cagatcacgc cattgcactc cagcctgggc aacaagagtg aaactctgtc 193980
          tcaaaaaaag aaagaaagaa aaaagcccaa aggagactct gaattttaaa acaactactt 194040
          tgaggccagt cacggtggtt cacgcctgta atcccagcac ttcgggaggc caaggcagga 194100
          ggatcacttg ggccccaggg ttcgagacca gcctagacaa catggtgaga ccccacctct 194160
          acaaaaaatg tagaaattaa ctgggtgtgg tggaacatgc ctgtagcccc agctactcag 194220
          gaggctgagg tgggaggatt gcttgagcca gggagttcga agctgcaatg agcgatgatc 194280
          atatcactgc actccagcct ggtgacagag ggagaccctg tcttgaaaaa ataaataaaa 194340
          caaaaacaac tactttgaaa aagggatcat taggtgaaca actgaagcct ctgaaactaa 194400
          acagtctcag ccaggtgcgg tggctcacac ctgtaatccc agcactttgg gagtccgagg 194460
          cgggtggatc acctgaggtc aggagtttga gactagcctg gccaacatgg tgaaaccccg 194520
          tctctactaa aaatataaaa aattggccgg gtgtggtagc tcacgcctgt aatcccacca 194580
          cttcgggtgg atcacctgaa gtcaggagtt tgagaccagc ctggccaaca tggcaaaacc 194640
          ctatctctac taaaaataca aaaattagcc aggtgtggtt gtgcatccct gtaatcccag 194700
          ctacttgaga ggctgaggaa ggagaatcgc ttgaacctgg gaggcagagg ttacagtgag 194760
          ccaagatggc accactgtac tccagcctgg gcgacaggag caaaactcca tctcaaaaaa 194820
          gaaaagaaaa gaaacgaagc agtctcaaag aaatgtttgt acacttgtgt ttatagcagc 194880
          actattcaca acagccaaaa tgtggaaaca acccagatgt ccatgggcgc atgaatgggt 194940
          aaagcaatgt ggtatgtacg tacaacgggg tattatttag ccctgaaaaa ggaagaaaat 195000
          tcagaggtcg ggtgcagtgg ctcacaactg tacctataac cccagaactt tgggaggccg 195060
          aggcaggagg attgcttgag cccaggagtt caagaccagc ctgggcaaca tggtgagatc 195120
          ctgtctctat acaaaaaaac aaaaaaaatc agccagatgt ggtggcacat gccagtggtt 195180
          ccagctactt gagaggctga ggtgggagga ttggttgagc ccaggagttg aggctgcagt 195240
          gagctgtgat cataccactg cactccagcc tgggcaagag agcaggaaaa cgcctccccc 195300
          agcatacaca aaggaaggaa attctgactc gtgctacaac atggatgaat ctcaagacat 195360
          gctaagtgaa ataagccagt cgctggccgg gggtggtagc tcatacctgt aattccaaca 195420
          ctctgggagg ctgaggcagg cagatcactt gaggtcagga tttcaagacc agcctgggca 195480
          acatggtgaa accctgtctc caccaaaaaa tacaaaaaca aacaaaacaa acaaaacaat 195540
          tagccagatt tggtagcaca tgcctgtagt cccagctact caggaggctg atgcatgaga 195600
          atcacttgaa ccctggaggc ggaggcaaca gtgaaccgag attgtgccac tgcactccag 195660
          cctgggcaac acagaccccg tctgaaataa ataaataaat aataaggcag tcacaaaggg 195720
          gcaaatactg tataattcca cgtctatgag gtatttattt tattattgtt attatttttg 195780
          agatggagtc tcgctctgtt gcccaggcta gagtgcagtg gtgcaatctt ggctgactgc 195840
          aacctctgcc tcctgggttc aagcgattct cctgcctcag cctcctgagt agctgggatt 195900
          acagtagcct gccaccacac ccagctaatt tttgtatttt tagtaaagac agggtttcac 195960
          cacattggcc aggctggtct tgaactcttg atctcaggtg agccacccgc cttggcgtcc 196020
          caaagtgctg ggattacagg catgagccac catgcctggc cctatgatgt atttagagca 196080
          gccagaaaaa tagagataga aagtggaatg gaggttgcca gggctgggga ggggaatgtg 196140
          gagttgtcat ttaatgggtg cagagtttca gttttgtaag atgaaaagag ttctggaaat 196200
          gaatggtggt gatggttgca taacaacgta aattaactta atgccactga actgtgcact 196260
          caaaaatggt aatgatgata actttatgtg tagcttacca caattcaaaa taataaaagg 196320
          atgggtgagg tagctcacgc ctgtgatccc agcactttgg gaggccaagg tgggtggatc 196380
          acttgaggtc aggagtttga gaccagcctg gccaacatgg tgaaaccccg tctctactaa 196440
          aaatacaaaa attagccagg cgtggtggcg ggtgcctgaa atcccagcta cttgagaggc 196500
          tgaggcagga gactcacttg aacctgagag gcagagattg cagtgagctg agatcgtgcc 196560
          actgcattcc agcctcggca acagagcgag actccatcat cctaggcctt gcacagatga 196620
          ggtggggcct ttgattaaga gctcagcggg gaccaccatg ccccctcccc acctgccccg 196680
          agacatcctc agaccagcct caaaggccca cagctggatt ggccagcctc aactttgcat 196740
          gctgtcggtg ggcgtggaaa tggatccagc ctccttgaag gtgccactca ggaggatgtc 196800
          caggaaatct taaacgtgag tgaaggcaag agctcctgag tggtgggttg ggatctgaac 196860
          acagccccac ctggttctag cacagccctg gtcctcattc ttcttggtcc agccaggcac 196920
          cgtgggctac atcatcctaa gaaaggggaa taaaaccaga gagggtagag tcagggcctg 196980
          gatccaccct gattaatctc ccatccagag aatacgaaag gcaatgccag gaagatgttc 197040
          taaggtcaaa tgaaccatct atgaactcac gcttccttct acagagcctg tggcttacaa 197100
          agcactttgg ctgggcgtat ctcttccatt tccctggagc tgccctgacc tggggaacac 197160
          caacctcgtc tccctctcta cagacttctc cacttaaaat ggccaagaca ggggctgcct 197220
          tttctggggg ttctggggta ttcctggggg agatcaaggc tgggggcagg ttgatggtgg 197280
          aggtgcaggg tgccctgaac tgggagtcac actgtaggct ccgcagcagc cggaagaggg 197340
          ctcaaaatac aataaggata aataaaactc aggcttcctt tctctctctg tctctttttt 197400
          tgagacgggg tcttgctctg ttgcccaggc tggagtgcag tggcacaatc ttggcttgct 197460
          gcggccttga cctcccattc tcaagcgatc ctctcacccc agcctcccga gtagctggaa 197520
          ccacagcaca tgccaccaca ccttgctaat ttttttctat tttttgtaga gatgggggtc 197580
          tcaccatgtt gcccaggctg gtcttgaact cctggcctca agctatcgtc ctgccctggc 197640
          atcccaaagt gctgtggcgt gagccacact gcacttggca gccttcgttt ttttctttcc 197700
          tctttttatc agaccaatac aggcaggtga tttttttaaa agtcagattt ttaaaaaacc 197760
          tgacagtaca aagaggttta taaagaaaag gattccctcc tgctccgcct ttctcatccc 197820
          cggagataac ctcttttgac ggtttccgtt ttaaatcatg atggtggtca cctcctcagg 197880
          tccaaataat atggctacag tgctgttgct tgatttatgg accttagaaa tggcccaccg 197940
          atttcccgct gcgatcgatg aggactcagc tcgtcggcac tgccactccc agccccagtt 198000
          cagtttccga gtctacctct agttcgtctg ctgcttactt gctaacttgg aattccatct 198060
          gagacccagc ctgaggccgt cacctgtggg cagcgtctgc tctcctcctt ggggatggag 198120
          ggtaccaccc ttcctggacc ctcccatggt ttcctcagct cctgtctgct tttctctgcc 198180
          aaagttggaa gttctctcat cctgctctgc agggcagctg cctccatgcc tggtgggcag 198240
          agcgggtctt tcactccaca gcgtgcgctg aagtgttcgc agcgggtcct gcacggccag 198300
          gcatgtcctc cccacgttcc cagctgcgca ctggacacac ccaagtcaca ctggaccctt 198360
          cctgatgcgc caccgccacg gagggtccaa accacttccg gctttagatg gctttctgct 198420
          tggcccacgc cttcctcatg ctcaccccac tttgtgggga gtagcagctg tggccctaat 198480
          gtgccccgtg ccaccctgac tttaggtcgt ggactctgtc caggcttctc ctcaaagttc 198540
          acatcagcat cttcatatct ggaccaaaac tttctggcgc agacttttgt tgtttctggg 198600
          tttctaatgg cctttttttt ttttggcgct gcctcgttgg ttgtgccctg gagtcctgtc 198660
          gcctcgtgta cttcagcctt cgggttgagg ctgaggttcc tgttggactg ggggtgactt 198720
          ttgtctgccc acgtgggtgg caagtgagga gcagcatggg gttggctctg gccagagccg 198780
          agatcttcag ggcagtggcc aagccctggg tgcaggggcc gcccatgcca ccaacctgac 198840
          acctccactt ccagaagggg aagctggtcc gagttttatg gccgttggct gtcgaaactg 198900
          gacccacaga gccaagaccc tgtgctgcgc ccgctgcacc ctgagctgtc cagaggccca 198960
          gcccctccct acactgtgtc ctccatggcc cagaaagcac ttatgcacat gctcacacaa 199020
          cacacacacc acactcaatc cacacacatc acacactaca ctcaatccat acacaccaca 199080
          cagcacacac caatccacat acatacacca cgctcaatcc acacacacta tacagcacac 199140
          gccacactca accacacctc ccccacacac accacacaca acactcatac ctcacatcac 199200
          acaacacgct caatccacac accacacaca ctcacaccat gctcaatcca cacacgccac 199260
          acacaacact cataccacac atcacacacc acactcaatc cacacacacc acacatcaca 199320
          cactatactc aatccacaca cactacacag tacacaccat gctcaatcca cacaccatat 199380
          gcacatcaca ctcaatccac cttcaatcca cacacaccac ataccacact caaatccaca 199440
          tacttacacc acactcaatc cacacacacc acacacactc ataccaccct cagccacaca 199500
          caccacactc aaatccacac acatcaaaca catacacaca acacacacac aacacacaac 199560
          attcctacca cacaccacac atacatacca cgcacacaca cactcacacc accctcaagc 199620
          cacacacaca ccacacatca cacacacact acacacaaca ctcatgccac acacatcata 199680
          cacaccactc aattcactcc cacacattca cacaccactt acacacacac cccacactca 199740
          atccacacac accacacaca ctgacacaca tactacacac acaaacacac acacatacac 199800
          ggcatgtgcc cctctccctg ggctggtggg agcggaggcc cctcgagagg aaggcaggcc 199860
          ctgtgcccag gagcatcccg tctgcagaag gagtctgccc tccagcggga ggagtgaggt 199920
          accgaagcca gggccccgtg agaccccggc aggtgggcgg tgagcgagtt cgcaggtgag 199980
          gagggcgtgg gcactgcagg gcagcgggga cagcctgtgg agccgccagg aaccaaggca 200040
          gcaggcctgg atgccgggtg caggggcttg ggcttcatgg agaccaaaag ggctctctgg 200100
          agggtcttga gaaggaaagg gctgaggcca gactccagcc ttcttagagc tcgtcctggc 200160
          tctgggtgga gaatgggcct ggcaggtgag ggagctgcct aaaggcagtg tgcgctgagg 200220
          ccgctggcca gggacctgga ccacctgcca tggaacagtg cgtactgagg ccgctggcca 200280
          gggacctgga ccacccgccg tggacagtta cactgcttcc ctcacccatc ctctggtgac 200340
          acatcctccg gtgacacatc ctctggctgc tgttagagat ggaatttcac tcggtcaggc 200400
          ctggggcaaa ccactcagag gacacagggg gccaagggag cccaggcaac ttcctcgatt 200460
          cgcacctctg tacgggggat ccaggtcact ctattttctc accatttgag gggccgggtg 200520
          cagccatgcc gccgttgccc tgcatagaga caggtggctg ggctcagtgg ctcacgcctg 200580
          taatcccagc actctgggag gctgaggcag gtgtattgcc tgaggtcagg agtttgagac 200640
          cagcctggcc aacatggtga aaccctgtct ctactaaaaa tacacaaatt agccgggcat 200700
          ggtggtgggt gcctgtaatc ccaggtgctc aggaggctga ggcaggagaa ttgcttgaac 200760
          ctgggaggca gaggttgtag tgagccgaga tcacaccact gcactccagc ctgggcgaca 200820
          gagcgagact ctgtctcaaa aaaaaaaata gagacagggt ttcaccacgt tggccagact 200880
          ggtcttgagc tcaggtgatt tgcccacctc agcctcccaa agtgctgaga ttacaggtgt 200940
          gagccaccgc gcctgggccc tttctagtct tcttaaaatt cagttttctg tcaagagcag 201000
          caacccaact gtaaattact gtggtcaggg actaagtcac cttggtgtca tcctggtgtc 201060
          accctgatgt caccctcgtg ccccagcacc tagcatggcg ccaaattggt ttttgcagca 201120
          agaataagtg agtatggcac ttacaatgga aaaaaaccca atagacttta tttaattaaa 201180
          aacattaact ttctctggca gtcaaggttg gagccacccg ggagagccgg gcgtggcaaa 201240
          cacacaggcc cgtctggaaa gctctgccag cggggctcct gacccaggtc cagcaaaagc 201300
          agctcaaggt cagcctcagg gcctgacatc tcccaggaag aatccaaaac acccccgctc 201360
          ctcagcagca ctgtcctcac ttgcacaccg tcctcgcctg cgcaccgtcc tcgcctacgc 201420
          accgtcctcg cctgcgcact gtcctgcgcc ctcccaacct gcacttagca aggtcatgcc 201480
          ctgaggtttc agaacaaatc caactttcag gacaatttga ctagaaaata caggccaaaa 201540
          atccaccctg ggatctttgc tgcagtatag attttcttgt ttttgccctg aacgagtcag 201600
          ttaacgattc agattaacaa gagatctgag cctgggagta tctgggagtc atagagagaa 201660
          cagctacggg ccagggccat tagccaaggg gctgctgatg ctgggaggcc tggggcaagt 201720
          ggacgggctc acaggccagc tttgaggggg atggggtgga tgactctgag cccagaccag 201780
          acatctcccc acctcaggcg ctgtctcacg tgccgccttg tggggttaac tttgaatgtc 201840
          aaagcccaga attttcacta gggtcgcctt ccatcctgtc ccttcatttg agaagcggaa 201900
          agcgaggcac ctgtgtggga ctggcccagg ctgtgcagtg gctccccagg tgtcctggtg 201960
          gcacgtgggg caggaaagtc gcatcagtca gggttcccag agaggccgaa ccaccaggat 202020
          gtaacacaca cagggatgga ttgtcaggaa tgggttcatg cacttgttgg ggctgtaaac 202080
          ccggagtctg cagggcaggc tgcagcctgg acacacccgc gggagttgat gttgctgttc 202140
          ctagactgga ggcaggttcc ctcctctccc aggaaccgca gtctttcctc ttgaaggcct 202200
          ttcttgtttt gtttggcttt ttcacagtgt tggaatgtac atttcctttt tttctttctt 202260
          tctttttttt tttttttttt gagacggagt ctcactctgt caccaggctg gagtgcagta 202320
          gcatgatctc ggctcaccgc aacctctgcc tcctgggttc aagcgattct tctgcctcag 202380
          cctcccaagt agctgggact acaggtacag gccaccacac ccagctaatt tttgtatttt 202440
          tagtagacat ggggtttcac tatgttggcc aggatggtct caatctcttg acctcatgat 202500
          ccgcctgtct cggcctccca aagtgctggg attacaggtg tgagccacta tgcccggccc 202560
          tggaacgtac attttcttag cagaacttat taagaacata attacaaaag aatttcaaca 202620
          agtcaatgat agcatacaaa agaaagaagg gaaaaaatat atattttatt gagacagagt 202680
          ctctgtcacc tagacaggag tgcaatggca tgatcttggc ccactgcaac ctctacctcc 202740
          tgggttcaag ggattctccc acctcagcct cccgagtagc tgggattaca ggcacccacc 202800
          atcatgcccg gctacttttt gtgtttttgt agagactgga tttcaccatg ttggccaggc 202860
          cggtcttgaa ctcctgacct caggtgatcc gcccacctcg gcctcccaaa gtgctgggat 202920
          tacaggtgtg agccaccacg cccagccaaa aatatctttt aaagtactca ttattttcac 202980
          tttgttggga aggtaggtat ttatatttaa tagttgaggg aatatcgaat gtttcttttt 203040
          aatagatgct aagcaggata gttagtaacc gacatgttta atattcaaag ttaaaatact 203100
          tgagaacaag tattaggtat ataggaaaat ggaatggaag tttctccacg tttgtctttc 203160
          catagccaaa agaggcagaa acttttcttc tgagtctctc agaagaaatt ccaagaagac 203220
          tagaagccgc tggcatgaag agtaaacgtc taactatcaa aaccatggca cgaaagccgg 203280
          gggcccctgt agaaactgca aaatttggag gccgtggaat ttgtgataat attgccaggt 203340
          gagcacatct caaaaatgat attggcaatt atatttcagt ataggttgtt ataactaaca 203400
          gaaatgaaga aaacccgcga gccgggaccg cgggggaagg tgtccccggc gtttgccgcc 203460
          tgccgagcgg ttcggttctc ggctccctgg cagccggcct tcaggtcggg cgtcttcgtt 203520
          ggtgacttct gctttggccc tcccggtgtg gccgctggtt gggctgcact gctgtgaccc 203580
          atcatcatct cctgaagctg catcctgtcc tgacttgcct ccacgcttgc acactgagaa 203640
          atgcagcacg ttgattcact tgcttaagga atgtcacaca aatcacagca ttctgaaatt 203700
          tcttggtcat tgtaaccatc ttgattggga gatgagaaaa tgcctgaaga aggagtacat 203760
          agaaaagagt tctggccagg cacggcagct cacgcctgta atcccagcac tttgggaggc 203820
          cgaggcaggc agatcacgag gtcaggagtt caagaccagt ctggccaaga tggcaaaacc 203880
          ccatctctac taaaaataca aaaaaattag ccaggcatgg tggcacacgc ctgtaatccc 203940
          agctactctg gaggctgagg cagagaattg cttaaacctg gaggggtgaa ggttgcagtg 204000
          agctgagatc atgccactgc actccagcct gggtgacaga gcaagactcc gtctcaaaaa 204060
          aaaaaaaaaa aaaaaaaaag agttcaagac cagcctggcc aacatggcga aaccctgtct 204120
          ctactaaaaa ttagctgggc gtagtggtgc gcacctggag tcattcccca gagctggagg 204180
          tgggtcctga atcaccacag gcctcatgga tgtcccgctc tcccctgtgt cctgagtctc 204240
          tgacggtcag gccccagcac ccagccaggc ctcctctgag gaatggccac aatggcaggt 204300
          ttggaaagcg gcccagacat cacagatttc tgtaataatt cgagatcatt tggggtccag 204360
          ctcccaggca ctgtctcact tcattcccga agtgtgaaac tgtgatatta ggaatttgaa 204420
          tacagccagt ccctcctgac tgctggcgcc tgtcctttca ggagggtgac gcaggccact 204480
          ccgcatcagg gtggataact ctgggacctg ttttttaacc cttgatattt accgactttg 204540
          gtcagttcac caatccccag tctcaaattt gcgaaagtaa atgctatgcc cttttcatag 204600
          agctgtcatc cataaaaact gccactgtgt tccctcactc tgtcccccaa tgagccctgc 204660
          agcaggtggc ctgctgccac gctgggaggt gctctgagga caagcccatg cgtgctggtg 204720
          acagctgcag ccccttccct ctgtggtcct gcctggctgc tggtccagag ccccttcccc 204780
          agcccaggat ggctctccat ccctttgggt gcctgagaga gcaaacacct ggtctcatat 204840
          caccggcagt tgtggactgg ctggacggtg ctgagagcgg gaaggaaaga ggggcagagg 204900
          gcatctgagc ctggattcct gctctttctg ccagctctga cctggaccca cacctcctcc 204960
          cagcccccat ccaaagcaga gaggaggcac aatcagaaag ggaaaagtaa aagaggaaag 205020
          aggggtgcaa ggaccaaaga ggcacgcttc aggtaccaca aagtgatgag gctgcacccc 205080
          aaaccccatc accataatca tctgctatgg actgagcatg ttcatctgtc caccactgca 205140
          tctggctctc tgtataaatt atctcacata cagaagcagg tcacagccca ccttgtgcct 205200
          cccctctctt ctctgctgcc cccttgcaat catgcaaact catcgtccat cttaaaaata 205260
          cggctggaat ggggagcata ccccttcaaa tatcagtctc ttaattgaaa gatgtgcaaa 205320
          gacacagttc gtactcaatg cttcattctg ttaatttctg cattgttgtc tatttgtaaa 205380
          gttctgtgtt cataacaaac tcttttttaa tgttatgatt tggttttttg tttgtttgtt 205440
          ttgttttgag acagagtctc gctcggtcac ccaggctgat gtgccgtggc acgatctcgg 205500
          ctcactgcaa tctttgcctc ccaggttcaa gccattctcc tgcctcagcc tcccaggtag 205560
          ccgagattac aggtgcctgc caccacgcct ggctaatttt tgtatttgta gtagagacgg 205620
          ggtttcacca tgttatccag gctggtctcg aactcctgac ctcaggtgat gtatctgcct 205680
          tgacctccca aagtgctggg attataggca tgagccactg cacctggact tgttttactg 205740
          aaatcactgc agcaggcttt gagtgcctat tagtgactca ctttcactga gcaagaggta 205800
          gattttaggt ctgcaacaca gcacatgccc ttgacaagct cacaaacttg taggagggat 205860
          aggcctagac ctgtagacca tgtgtaggag ggaccaggca tagctcccag ggagggggct 205920
          gcccataagg tggtcctctt gtccaaagtg aaatggctca tatgacgcag cctccactgt 205980
          tctgaattct gcctctaaag aacccagaaa atgctgtccc gcaagaggat tccttaggta 206040
          atgacttgag tccatgagtt ctcctagaag catttctcaa gttagactga agaaaacatt 206100
          ttcttttgag ccaaacttcc tttcattggt ataatcctat ataggtagcc aaagcccttt 206160
          tacttgtatc atctactttt attcttacaa caaccttagg gagtgggtag gaaaaaaacc 206220
          tactctcacc ccatctcaca aataagggaa attacaaggg tattgagtgg tgaattttgg 206280
          gaaagaaaat ctgttccttg tccagaaatt catttattca tttatctttg catccatcca 206340
          tgcatccatc catctaccca cccacccatc cacccatcca tccacccatc cacccttcca 206400
          cacgttcacc catccatcca tccatccacc catacatcca tctacccacc cattcatcca 206460
          ttcaaccatt catctatcca cccatccacc cacccatcca tccactcatc tatccatcca 206520
          tccatccatc catccatcca tccatccatc catccatcca cctacccacc catccatcca 206580
          cccacccatt caaccattta tccacccatt aaaccatcca tctactcatc catccatcca 206640
          cccatccatc tatccattca cccactcatc caccatccac attcatccaa ccatccatcc 206700
          tccatatatg tgttgggtgg gtccctatta accagtccca gggctatatg ctggaggacg 206760
          aaggaggccc tagctttcag ataactccca gtctggaatg tttggatcct ggagattatg 206820
          gcagtggctc attttctcct taacaactca atattattac cttacccaaa tacagtctga 206880
          ggacaggcaa agcaggaagc agattccttt cgttggattt ggggtgtggg tgcagctgca 206940
          agcagtaagg cacagagaag aatactggtg tcccataagc ccctgagggt caccacacta 207000
          agtgctgggt cgtaagttgt atcaaatgta ctgcctgagc ctttagtcaa tcctgtgaga 207060
          ggatttctgg tctctccctc aacactaaga ggtagcaaat cttctcttga tggattaatg 207120
          gatctaagag tcacgagggc tcctgattta tagcctgcat tcacgtctgc cctctgcata 207180
          gcctggcaga atcttagagg aaagttcttg ggcagcaggg tcaagtaaag gttgttattt 207240
          taaagagagg ggagaacatt gtgtcaacac aggaaggatg tcatgaagaa tgggacttgg 207300
          cagttccctg cggctgggag gagggtccac atagtacgac agctctctgc cttcccaatc 207360
          cagtcactca tcccttttag agctcagact ctggcaaaca gactcataat aacccaactc 207420
          acaagagact gaatgatggc aatgtgcttc ttcctagtag gaggtaggtt cccagatctg 207480
          cagccagggc ctctggcctg cagtaggtca tccccactgg agccgagcca ggaaagaaga 207540
          gcctttcatg tatgttacca catgtaagcc tcttacagcc aactccttaa ggagctatga 207600
          ctgaggttca ctgaaggggc aggaagtatc ccaacgtggc ccagcttgcc agagaagagc 207660
          tggactttaa ctcaggccca gggctatttc ccggcctgcc ttccttcttc tctacctggc 207720
          ccagtggccc accatagcct agttgttaga ccctagaggt caataaacct agtctcttcc 207780
          ctggagactg aactgtagtc cagaattgag attgtgcgta tgtgacatgt gattcctgga 207840
          tacataagac aacacacaga gcagagggat tgatccttac attttcgcag tcagggagat 207900
          gctgagctgt gtctctgacg gtgaatatag aattgtaacc aagggagctg atgttctcag 207960
          gagatgtttg cagccgggtg gagaagctca gtgcatgctt ttggggctac ttctggttaa 208020
          ataatagaga ataagtgagc ccacaatgta gagataatgt gagcgagtgt tttgttgcgt 208080
          aaggatgtga gagtctgagg gtgtgtggcg tggatgcaga atgtgagatt attgcagaga 208140
          gtgaggctga ggaggctgca gcgcaggctt gggggataat tggaggatgc agttcccagg 208200
          gagagaaaga aggagtccag tcatggttag aaacaccaaa tgattgtact cattatttct 208260
          ggctcagtag caaattactc ccaaacttag tgacttgaaa caactttggt tattatggca 208320
          cagatttggc aggtcaggaa tctggctggg agagctggtc cctctgctcc gtgtcccccc 208380
          aaggccgtgg tcatctcaag gcccctctgg gaaggaccct ctttcaagct cattcacacg 208440
          gctgctggtg ggtttcagtt ccttgcaggc cgctggaccg aagcctccct gggttccttg 208500
          ccatggaggc tgccccgtag agcatcacac aacacggcag cttgtgttgt cagagcacgc 208560
          aatcaggagg gccaaaagag aggggaccag taaggcggag agtgacagca ggatggaagt 208620
          catagccatc cgtaacttag ccatggaaat ggcatcccat cagctttgct gcagtctctt 208680
          cctagaagca agccactagg tccagcccac gctcaaggta tgagcagcag gaatgggacc 208740
          actggggcct gtcagaagct gcctggcaaa acgactaaac aggaatcaag catttgctgt 208800
          gtggtggaca ccagctaagc cttttatgtg cactctgtgc tatgaccctt cacaaagccc 208860
          taccaggaag aggtcctgtt attattctca tttcatagat gaggacattg aggctcagag 208920
          aggttgggta acctgctcaa ggtcacacag ccagagaaca gcagagctgg aacatgaacc 208980
          caggcctgct gactacaaag ccaggacctc tccaaagcag aggtctccct gtcctccctt 209040
          gcgagcttgg acaggaagtg gggcgaggtg gggccgggaa agccgccttc ccagccagcc 209100
          tgcctgccct ctggctccac cgtctctgat ctttttccac tgtctttgct cgtttgactt 209160
          ttcccctgtt gttcctactt tcttcatcca aacaaatcct gtctgctcac atttcaatct 209220
          tccagctggg tgccagccag agtcctccct tcccttgaat atgcaagatt ggcatgcccc 209280
          atgcagattt gccacaagca gagtgggctg ctgcctccgc atggagcagg gggcaccagg 209340
          ggactctctt gctgtcccca gtatctcccg aatggcctgc ccccacgcct gggtggtcac 209400
          cattagcaat cgcttcattt gggttatagc agcgaggatg ctggcggttc ctgctgaaac 209460
          caggggaggc agaagcagca ggcagggagg cctttcccta cgcacacctg agactcccag 209520
          attgctttgg tagccaacag ccagctggga gctgggcctc aaggagttgg gatataggac 209580
          aggtcacttt aaaaaaaaaa aaaagtgtgg taagggccgg gtgcggtggc tcatgcctgt 209640
          aatcccagca ctttgggagg ccaaggttgg tggatcaaga ggtcaggagt tcgagaccag 209700
          cctggccaac atggtgaaac cccgtctcta ctaaaaatac aaaaattagc tgggtgtggt 209760
          ggcgggcgcc tgtaatccca gctactcggg aggctgaggc aagagaattg cttgaaacca 209820
          aaaggcggag gttgtagtga gccaagatcg caccactgca ctccagcctg ggcaaaaaag 209880
          cgaaactcca tctaaaaaaa aaaaaattgt agaaacatac aaataacata aaatgtaccc 209940
          ttgtactcac ttttgtgcac agttccgggg catttggctc attcacatga ttgtgcagcc 210000
          ttcaccgcca tccttctcca gagcattttc atcttctcaa acagaaactg tccccatgaa 210060
          acataaactc tccaccccac ccaccgcccc caggccctgg cagtttccat tccactttct 210120
          gtctctgcaa gtctgactgt gttaggggct tcatgcgagt ggaagttgac aggatttttt 210180
          tttctttgag acggagtctt gctctatcgt ccaggcttag agtgtagtgg cttgatctcg 210240
          gctcactgca acctctgcct cccaggttca agcgattctc ctgcctcagc cttcagagtt 210300
          gctaggatta caggcgcccg ccaccacacc cggctaattt ttgggtgttt agtagagaca 210360
          gggtttcacc atattggcca ggctggtctc aaactcctga tctcaggtga tccacctgcc 210420
          ttgcctccca aagtgctggg attacaggcg tgagccaccg cacccagctc agcatttgtt 210480
          cttttttatt tggcttcttt cgcttagcat aatgtcctca aggctcctct gtgttgtagc 210540
          ctgtgtcagt gtttcactgc ttttcgaggc taaataaggt tccattgtat ggagacacca 210600
          agttttgcgt atccgttcac ctagcaatga acacttgggt tgcttctgcc ttttggttgt 210660
          gtataaagat gccaggaaca tgggtgtgca aatatttgtt caggacaagt cacttggtga 210720
          tgaaccaaga aggggacagg tgtggagggt ggggctgctg gagctgccag ccttggaggg 210780
          aaaagcagag tggggggtgg tgggctggag gaggtccgga gcctggggga ggtgcagggg 210840
          agggagtagg gagtggggat gaggtgggca gcagcaggga tatctgtagg agacgctgcc 210900
          ttcccatgat accacctgcc ttgggcagaa ctatgttttc tccgtaactg gggtctcccc 210960
          agcattccaa agaggtaggg atatttgggg aacctgagag ctgtcaagaa acagctgtca 211020
          ggcagccgaa cctagacttg ctggcccata ttcaggattg cttccaaggt cgggatcagc 211080
          caagcctggc gggaaagagg caaatgctgg tcactgtctg gcaatgcatg atgtggcaaa 211140
          gggactgggc tgctgtgata cagagcactg ctcatatgca tgggtcagct aatgcctggt 211200
          aacaaacagg acctcagggg ctgcactagc actcagggct tagcaagttt ctgtattggc 211260
          cagttattgg cacaataatg atgaatgcca aaccagtccc aagctcgggg gctagctcag 211320
          catcactgat ttcctgggcc tgtggctggc atggctctgc ctcacaccac agattgggct 211380
          gggtctccca ccctcctggg ctcgctcggc ttactgaggc agcttcttgt cctggtgacg 211440
          gcagaggcaa cagaaggcaa gcccacccac gcacgcacgt ctgcaagccc ctggctttgc 211500
          tctgcctgtc ttgctggcca aagctagcct caaggccaca ctggacgtcc agggtcaggg 211560
          aagcagattc tgcctatgtg ggaggagctg caagtcacat gacagagggc agggacacag 211620
          ggaggggtgg tgagaattgg ggcaaagctg ccacctttct ggaatgttcc aaaagaagat 211680
          ggacgactac tgctcctcgg ccctggaagg gagagttctt ttttccccac tataaagttt 211740
          tctgattcca attccaaaat gctatgactc ttaatcaatg cctgatgaac catacttgag 211800
          caaacataat ttattctctg tcaagatcat cctgagggga tcgggtgtct ttgtttccct 211860
          cctaaatccc ctgcgaattc atctttttta ttccaggctt actaggaaat aaaagatttt 211920
          gtctgagggc tgatgggtat tagcagagct atatggagct tgagttgaaa cttggaatgt 211980
          ttgtggatca aaaccgagct gtgctggcag cgtctgggag gagggtgcac tcgctgaaac 212040
          tctgcccgag ttgtggctgt cagctgcctc gactgccaga ccagactcgc tgttttgggg 212100
          ccgggtgggg gggacggcgg ggggagtgtt gttacggatt gtgctggaag gttttcttgc 212160
          tcttggcttt tttggtgaag ggcctggatt actgcagaaa atccagctta tgtgtccaag 212220
          ggcaaagcag gcctgtttat ctttaacttt tacatgcttc acacatctcc tgaggtttga 212280
          ctctaagcag gatttgtgtc ttccctgatg caagaaaaca ggaggcaggc gctgagcttg 212340
          caggaggcca cacagccagt gcacagcttg ccatatgctt aacgtggctc tgagaagaga 212400
          gggttgtttt tttaatatta aaaatggcta tgggaaaatc tgccctaatg ctattaagca 212460
          gtgctgatat gagatgtgtg tggctgtaac tttctgattg gatttgggat ctaggctgca 212520
          gccagccaga cgctggagac acattcctga gccacctcag cccttgcctc tttgccgagc 212580
          tgcggctatt ctttggggca cgcaggtaga tgcagagaga ctgaagtctt cagaggtggg 212640
          tgtgcacaga agagtgattc ccagatcagg gaagactttg gcccccagat gacatttggc 212700
          aaagtctaga ggccttttca attgtcacaa ttgggaggag ggaggtacag tagcatctgg 212760
          tagatagagg ccagggacgc tgctcgacgc ctacagcaga tggactcaca gccaagaatc 212820
          atctgcccct aacattattc agccttaact tacaaaggaa ggaaagtctg gtgcatgtgt 212880
          gctgtggttt gagtgtgtcc tctccaaaat tctgtgttga aacttcatgt ccctgtgtcc 212940
          taattgcctt aagaggtgat taagtcaaga gaacgcctcc ctccataaag ggattagtgc 213000
          ccttataaaa gggctttgag gctggataca gtggctcacg cctgcaatcc agtactatgg 213060
          gaggccgagg tgagtggatc acttgagccc aagagttcaa gaccagcctg ggcaacatag 213120
          tgagaccctg cctctaaaaa aaaaaaaact gggagtggtg tcacatgact ttagtcccag 213180
          ctatttggga ggctgaggcg ggaggatcac ttgagtacag gaggtcaagg ccatggtgag 213240
          ctgtgattgt accactgcac tccagcctgg gaaacagaac gagaccctac cataaaaata 213300
          ctactactaa taaaagagct ttggtgaagg gagtttgtcc ctcttgcctt tctgccctcc 213360
          accacgtgag gacacagcgt cccccccacc aggaggaggc agtgctccaa gtgccatctt 213420
          ggaagccagg ctggaccctc tccagacagc gaacctgctg agccccggat ttcggactcc 213480
          cagcccccct ggcaaaggcc cgtgttctct tccaacatgg tctagtggct acatctttgg 213540
          gagggggcga atgctgaggc ctcacatggt ggacccactc cctctggccc tttgataggg 213600
          accctaattc catccgtgaa gtctccaccc tcgtgacctc atcacctctt acggtgtcac 213660
          ctcttaatcc cattacaatg gtgagtaaat gtcaacatat gaatttttga ggggacacca 213720
          tcatgcaaac catggcagtg gtgccggcta tgtaagtagc tatgactgtg cagaggtcac 213780
          catggccatc tcacatgcat gtcactcaac catcaaaact cacccaacag cagttgccca 213840
          aagcccccca ccctgcccca cttgtaccca caggcactcc agtcccagct ccaaattaca 213900
          tttgtgcagc cttatttctc caagtggctt cccacaagct tgagatgcag gtggtcgtca 213960
          gggaaggtcc tcatctctcc ccattggcca acttggtttt atatcacctg ccctgaagtc 214020
          cctctgccag aggagagcca gtgactgtgc caggtgcttc cttggacaca cccaagctgc 214080
          cgtcttaaag aatcaccccg tcaagctctg ccacgttttg tcatccggcc ccacatttcc 214140
          ttcagctgta tctcccaccg ttcccaaatc caacaacggc gcctgtgcgt ggccaggagc 214200
          gcagagaggc aggggtggga gttcccccag agcctggctc cagctcacag ctcagacacc 214260
          ccgtggccct cctgccctgg gcccggatga gtcgggaata cgggactgct ctccaaggtc 214320
          cccccttccc cgtctgcagc cagtcagcct ctgagtcctt atcatctgtt tcccaaatag 214380
          ttccagatcc ctccctctct gcccttcccc cctcatgccc aggtttgggc cactattaca 214440
          atttacctgg attacctctg cagattccca ggctgccgtt ggcaacagtg gaaggtgcag 214500
          atgggggcga ggaagatggt ggcgcactgc ctctgtcctt ctctgctctg agttggagcc 214560
          aaccccgagg tctccttgcc cctggcacgc ccaatctcat tgtcatgcac cagagaagtg 214620
          gccgggaagc tccccggggc ctggtcactc ggcttagtcg gctctgtcac ttcccccccc 214680
          gcacctgctc agcccattga ctctctgact gcacctcagc ccctgccccc cgccaggcag 214740
          tcacctgcac ttctgcatcc tccaggggcc tctctttccc acctcagggc tcagtgcaaa 214800
          cggtgccttc tttctcgaat gtggataatg gaggaaaaat gttgcttccc cacgaagcct 214860
          tcccaaccgc ctaatttgga tgcagtgtcc catcctgggc ccttagccct gttgcagtgc 214920
          acggtggttg acggcccatc atccttctcc cctcaggaca gaggccatgt cttgcttgtg 214980
          gacccttgat cctgtgtgag ggacacgtgc ctcccaaatg cctgggctca gccttctctg 215040
          gaggcttctt cactttgtgg ggatcctcta ggtgtgtcgg ccacatgatt ccccttcact 215100
          gattcatcca gcaaattcat tcccctccac tgattcatcc ctgagcattg actctgatgg 215160
          gcaccagggc cgtagcaggc ccaggcagac ctcgctctca ctggcctctc ctgcggagga 215220
          gaagcagacg ataaacaatg gctgggctat gatgggcggt ggcggcgcag tggagagaga 215280
          tcagacaggg ggagggcaca gagagaggct gagggggctc ttttgggagc agccatagaa 215340
          aacttctctg agtgacgacg ttagagacct caaggaagtg agggaacaag caagtgttgc 215400
          tggcgttggg aacggcaagc gccgggcttg gggtggccca gggagagcac gggtcagcac 215460
          gcctggagtt cagcagcgtc agggaggtaa cagggtcgga tcctgtaggg cttaggggtg 215520
          atgttaaaca ctctggaatc atcctgcatg agatggggtc attggacgtt ttcgaaccct 215580
          tggggttcct cctctgattt aagctttgag agacccactt tgcaaagttc ccgctataca 215640
          ctctatcatt acatcctcac aaattgcctg ggcacagtgg ctcatacctg taatcccagc 215700
          actttgggag gccgaggtgg atggatcact tgaggtcagg agttcgagat cagcctgacc 215760
          aacatggtaa aaccccgtct ctactaaaaa tacaaaaaaa aaaaaaaaat aggtgtagtg 215820
          gcaggcactt gtaatcgcag ctactcggga ggctgaggca ggagaatagc ttgaacccag 215880
          gaggcagagg ttgtagtgag ccaagatcat gccactgcga cagagtgaga ctccatctca 215940
          aaaaacaaca acaacaaaaa taaatcaaca tatgggtaat cttttcccca ttctacagtt 216000
          gagaaaactg aggctcagag agaaagggta gtgacttacc tgagggtgca gagcttgagt 216060
          gtgttgaact ttgctggaat ctggctcaga ttcattctaa aggccccact ccagctgccc 216120
          tgcagtagga atggcttgac cactctgctc cacaggccca aagacaggat ggggtcaggg 216180
          ccaaaatgag tggtggtaag gtccaactcg gttcttcgag aagtaaatca gctcctgaga 216240
          cgtcgatctt ccagctgcac cctgtcacta ttgagaccta gccaagcact tgggggcaat 216300
          tatatgggtg gctgtggctg tattggaagg cctgagagag gagggagtca caggtgaccc 216360
          tcttgagcag gagactcggg cccaagattc agggactgcc accttggtga cagtgtcaat 216420
          gttggatgat tttaggtaaa tgatgccttc acagaggcct ttaacccagc ggaaaccagc 216480
          ttggcaggta catgcttttt tccttccttt tcggtttcat tctaccaacc tccctgattg 216540
          ggttataggt ggggttctcc gaagctccct ggaaggcccc tcaggcttac tcgggagtgt 216600
          ggaggtggag gggattattt gctcactccc caggagcaga ggagggagac tgtcccttga 216660
          ttgggggatg ctctgagaga tgccgtctgc tgtgaggcgg gaagaggagg ggctccccgg 216720
          tcctcccggc tgctcttccc acctcttttg ggagcatggg atggaagatg cataaaaatt 216780
          caaaccatcc tgaaaataaa tgaaaggaaa atatatatat ccaagaagga gataaccata 216840
          gcaatcactt tcactcaaag gtaataaaaa taaggatcgt aaacataaac tcagaaattg 216900
          caagctgcac tccctgccga cgtttgctgc catgagagag cacattccga gggaaggcaa 216960
          ggactttcca gactttccag gacactctgg acatgtctct ctgattgaaa cctccagaag 217020
          gaaaaatatg ggaggaaaat agtgagttat gggggggaaa taaggaccca aactataaca 217080
          aaaatggaga acacaaatta tgtttacaaa cgtttccctg gctgacagag actctgcctg 217140
          gaacagatca catatcataa ggtggccacc ttcccagggg tgggggctcc tgggtgagta 217200
          cagagtgttc tgtgagtgac ggccccccct ccctgcccgc ccccctccgc cagcctcatg 217260
          gagctgcact ggagatggct tattctgagc gtcagctgcc gccttcctcc tctgcagcca 217320
          tcagaccgaa gctgccgctg tgacaagcaa accagacaag atggaccgcg gcagctgggc 217380
          tgtctgcaga gggccatcca ggcctccttg ctagaaacat gcattttaga tggacaaacg 217440
          gaacattttg tcctctttgc cttctgatat ttgtcttctg ccagaagaga gctaggaccc 217500
          aggcatcaaa ctacagccag tgaaatgttc ctaactccct gcttgggttg catcctgcga 217560
          cggctgctca ttgcccgaca aacgcttcgt cctgcctggg catcatcctt cagctgtaac 217620
          cggcgatgcg attcccaagc actgtttaaa ctttccagtc aaaaatgaga caccactgct 217680
          cacttatcag atttgcaaaa atcaagataa taaagctaag gaaggctggg tgtggtggtt 217740
          caggcctgga atcccagcac cgtgggaggc agaggaggga cgattgcttg agctcaggag 217800
          ttgaaagttg cagtgagccg cgatcatgcc actgtcctgc agtgtgggtt acagagtgag 217860
          accttgactc aataaaataa aatataaaat aaaataaaaa ataaataaag ctaaggagga 217920
          aaaccaaaac atggctagtc agtttgggga aggtgggacg acacggtgtc ctcatgccgg 217980
          ttcgtttgca aactggaatg atcttttcgg aaggaatgta ggagtgtctc aggaatctgt 218040
          aaaaagttca cagccaggca tggtggctca cgcctgtaat cccagcactt tggaagtcca 218100
          cagtggcagt atcatttgag cccagcctgg gcaacatggg gaaaccctgt ccctacaaaa 218160
          aatacaaaaa atatttgctg gatgtggtgg tgcatgcctg tggtcccaga tgctcaggag 218220
          gctgaggtgg gaggatcctt tgagcctggg aggcagaggc tgcagtgagc catgattgtg 218280
          ccactgcact ccagcctgga tgacagagtg agactctgtt tcaaaaaaga ataagttccc 218340
          caccttgatt tgctatgagc tgaattgtgt cccccagaaa tccagttcca agtcctaacc 218400
          ctggtgcctg tgaatttgac tttatttgga aatagggtct ttgcagatgt aattaaagtt 218460
          aagatggtat gtctgctgtc tttattttat ttatttattt tttctgagac agagtctcgc 218520
          tctgttgcct aggttggagg gcagtggggc gatctcagct cactgcaacc tccatctcct 218580
          gggttcaagt gattctcctg cctcagcctc ccaagtagct gggattacag gtgcacatct 218640
          ggctaatttt tgtatttttt tttttccagt agagacaggg tttcaccctg ttggccaggt 218700
          tggtctcaaa ctcctgaact cgagtgatcc gcctgcttcg gcctcccaaa gtgctgggat 218760
          tacaggtgtg agccactgca cccagccgtc tgctgtcttt atgagaggag agacacatag 218820
          ggagatggaa ggccctgtta ggatggtgcc agaggtagga gggatgcagc cgcaagctga 218880
          ggcatgtagg aggttgctaa ggacaccttg aagctgagag aggggcacga acagattctt 218940
          cctgggagcc tggaggcagc agaaccatgc tgacatcttg atgttggaat tctggcctcc 219000
          agaaccgtgg agcaatacac ttgttgcttt aagctaccca gtttgtggta ctttgttaca 219060
          gcagccctag caaactaaga cactctattt ttatgttttt tgagacggag tcttgctctt 219120
          ttgcccaggc tggagtgcag tggcacgatc tcagctcact gcaacctctg cctcccgggt 219180
          tcaagtgatt cttctccctc agcctcccag tagctgggac tacaggctcc caccactacg 219240
          tacggctaat ttttgtattt ttagtagaga cagggtttca ccatgttggc caggctggtc 219300
          ttgaactcct tacctcaggc gatccactcg cctgggcctt ccaaagtgct aggattatag 219360
          gtgtgagcca ccgtgccggg ttacaaacta atacactctt tttgggcttt tactttcact 219420
          tctaggaaga aatattgtag ctcattattt tccacattta tttttatttc cacatagtca 219480
          gactatattt cccagtgtcc tctgcagtta gctatggcca tgtgatcgag ttctggccaa 219540
          tagaatgtgg ccagaagtga cataaacgcc agacccggcc aatggaaacc ttgtgctccc 219600
          gttcgggggt ctgtgccccc aaggttaccc cctaacacct actgaactac tgtatgtgtg 219660
          aaaaatggcc ttctattgat gctggggagt tactgttcca gtacttagca cagcttggct 219720
          aatacaagga aaaatcagag ataaagaaaa gcaaagattc acaggccagg atgtttccat 219780
          attccacatc atttactggg ggcagcagcc ggggcacaag acaaactcac ttttcttttt 219840
          tttttccttt ttttttgaga cagagttttg ctctgttgcc caggccagag tgcaatggcg 219900
          cgatctcggc tcactgcaac ctccgcctcc caggttcaaa tgattctcct gcctcagcct 219960
          ccctagtagc tgggattaca ggcatgtgcc accatgactg gctaattttg tatttttagt 220020
          aaagacgggg tttctccact ccatgttggt ctggctggtc tcgaactact gacctcaggt 220080
          gatctgccca cctcggcctc ccaaagtgct gggattacag gcatgagcca ccacccctgg 220140
          ccactcactt ttcttttaat attcagggca gcatgacccc aagtctttgt cctttatatt 220200
          tctgggcagc cattcctttt gggatgtcat aggggtccct ttaggccctc cccagatcag 220260
          cctcctgccc cactgctccc tccatctggg gtttatccca ttgctgtgga cagagagagt 220320
          cgtcagtatg ccttggggcc agtgttcact ctgggctgtc tgagctgttc aaactctccc 220380
          tgccaatgtg tgttccctgc tcctgtttct gcttctagca gtagctcctt ggggtcctgc 220440
          tcattggagt catttgacaa tactgggcca ggcatggtgg ctcaagcctg taataccagc 220500
          cctttgggag gcagaggcag gcagatcgct tgaggtcagg agtttgagac cagcctggcc 220560
          aacatgggga aaacctatct ctactaaaaa tacaaaaatt agccaaaaat cgcttgaacc 220620
          caggaggcag aggctgccgt gagccaagat cgtgccactg cacttcagcc tgggcaacag 220680
          agtaaaactc cgtctcaaac aaaacaatac tatgtgccca cactgcatac caggcgctgg 220740
          ctctctgcag ggggtaaaag ggagaatgag acagatatga tccctgtctt cgtggagctt 220800
          ctatctggcg gggcaaaggg acattaaaac aatgtttaat tagaatagtg attagtgcaa 220860
          tgaatacaat gtatagggtc ccatgggagt ggatacaagg tagggtgact atgttttatc 220920
          atccaaatca gaacaccttt gagaatgtaa gaggacacta ttaataatta tgccagagga 220980
          atgagtgaaa accagggctg cctcagggaa ggcagaacct ttggccacct aggaggagac 221040
          caacccagtc cccgacaagc tgtctctgag cagctccctc ccagctttgg acccagccct 221100
          gaccaatagc tcgggggagc ccacacagct tggatgagtt ctcccaggct tgactgaacc 221160
          tcactcttca gaaaacacct taccacctcc ttcagggccc aggtgggctg gaaacaagtt 221220
          ccctgtatgt gattaacaca atggttgaga atacaggacg aagctgtggg tctcacagtt 221280
          tgctacgcat ggactcacct gggattccag gctgactctg ggctgccatc ccctaacatt 221340
          gtgatgaaat gggtgcaact ggggcatctg gaattttatt gattgattga ttgattgaga 221400
          cacagtctca ctctgtcacc caggctggag tgcagtggca tgatctcggc tcactgcaat 221460
          ctccgcctct ggggttcaag caattcccgt gtctcagtct ctctagcagc tgggattaca 221520
          ggcccacacc accacacctg gctaagtttt gtatttttag tagagacggg gtttcaccat 221580
          gttggccagg ctggtctcga attcctgacc tcaagtgatc tgcccgcctc tgcctcccaa 221640
          agtgctggga ttacaggcgt gagccaccgc acccggtcat tatttattta tttatttatt 221700
          tatttatttt tgagacagtc tcactctgtc acccaggctg gagtgcagtg gcacgatctc 221760
          cactcactgc aacctctgcc tcccaggttg aagcgcttct cctgcctctg cctcctgaat 221820
          agctgggatt acaggcatgc gccactacgc ccagctgatt tttatagtag tagagatggg 221880
          gtttcaccat cttggccagg ctggtctcaa actcctgacc tcaagagatc cgcccgcctc 221940
          ggcctcccaa aatgctggga ttacaggcat gagccactgc acccaaccga tgatctttta 222000
          ttttcaaaat gtttcagaat aatttttttt aaatgtcaaa taatttttaa aaacgtggca 222060
          aaaagaaaag gaaaaaagga aattcacaaa atcagaacac tgattcctct gcttaacttt 222120
          tattttcttc atttttggga acattttcca atttcctcca acaagcatct attacttttt 222180
          acttttaaaa tttaaaataa aaatggtcaa agtatgacgt gatgctgttt aaaatgtcaa 222240
          atggtatttc tgggatcata ataccagtgg gtccctggcc tccccatttc tggtcctgtg 222300
          acccttggtc cacatgtctg ggcagagtga gatcctgtct ttaaaataca tctcagcatt 222360
          tctacacgtg tctacggtct ttttctttgc gttttaaaaa ccaggttaca ggccgagcat 222420
          ggtggctcac gcctgtaatc ccagcacttt gggagtccga ggcaggtgta ttgtttgagc 222480
          tcaggagttc gagaccagcc tgggcaacat ggtgaaaccc tgtcactaca aaattagtcg 222540
          ggtgtgggct aggcgcggtg gctcatgcct gtaagcccag cactttggga ggccgaggtg 222600
          ggcagatcac ttgaggtcag gagtttgaga ccagcctggc caacgtggag aaaccctgtc 222660
          tctactaaaa atacaaaaat tagccgagtg tggtggcaca cacctgtaat cctagctact 222720
          cgggagggtg acacaggaga actgcatgaa cctgggaggc ggaggttgca gtaagctgag 222780
          attgtgccac tgcactccag cctgggcaac aagagcgaaa ttccatctca aaacaaaaac 222840
          aaaaacaaac aagcgaacaa aaatgtgatt gtgctacagt attatgacca ctacagcctc 222900
          actaggtgat aggaattttt cagctccatt gtaatctgat gggaccaccg tgctatgtct 222960
          agtccacctt tgaccacaac tgttctgccg ctcatgagtg ttacttacaa catccttatg 223020
          aaatagacac tgttagtttc ccaatgttac agatgaaatg gggctggggt aagtccagct 223080
          cctctcccag agcctcaggg caaggaattg acagagtgaa aactggaact gaggcctgtg 223140
          tgactcccag cacaagcagg cgctggaggg cccccggcag ccacttgcag gctaatgggt 223200
          gctcttgccc catgctgggc actgtgccac acattgcgag ggtctgcgct tagcatcagg 223260
          cagctgtgct tggaatcttt gcccagactt ggtcagtgga gagatcttca gaaagttatt 223320
          tcatccttgt gcgtctcaac ttccttgctg atacaatgga tctagaacac aagctcttcc 223380
          caggggttat taggagggtt acaagtgtta attctcagga aaaaggcttg gctccccatc 223440
          aatactcact aagtgttagg attatcctat tttacttaca ggcatatttc tctaatctcc 223500
          cctatgaaaa gcagaagcaa tggttggcct acctttgtcc cctcaggatc tactgttcag 223560
          ctgagagctt gagaatcact gatgttatgt aaatagtaca taaaataaca agtggggagt 223620
          ttaaaaagag acagttggtc acattctttg tattttcata gattattaaa atgaagggtt 223680
          acaaaaattc attttgcata ttattattat tattgttatt attattatta ttattgagac 223740
          ggagttttcg ctcttgttgc ccaggctgga gtgcaatggc atgatctcag ctcactgcaa 223800
          cctccgccac ctgggttcaa gcgattctcc tgtctcagcc tcccgagtag cggggattac 223860
          aggcatatgc caccacgcct ggctactttt tgtattttta gtagagacgg ggtttcaaca 223920
          tattggtcag gctggtctgg aactcctgac ctcaggtgat ctgctcacct tggcctccca 223980
          aagttctggg attacaggcg tgagccaccg tgcccatcca gtttgcatat tatatattgg 224040
          ataataaatt ttctcaacat agtctcaatc atataaactt tcctccccca ccccattttt 224100
          cttttttttc tttttttttt tttgagacag agtcttactc tttcgcccag gctggagtgc 224160
          aagctccgcc tcccaggttc acggcattct cctgcttcag cctcctgagt agctgggact 224220
          acaggcgccc gccaccatgc ccagctaatt ttttgtattt ttagtagaga cggggtttca 224280
          ccgtgttagc caggatggtc tcgatctcct gacctcgtga tccacccgcc ttggcctccc 224340
          aaagtgctgg gattacaggc gtgagccact gcgcccggcc ccatttttct ttttcttttc 224400
          tttttttttt ttttttggag atgcaagttc ttttattaaa ttctcaaatt acccaatttg 224460
          tgtgggccat ctgtttccta cctggacctt gacacattca gaagtcaaca ggacactgtc 224520
          cgaatgggtt ttggttagta acttccttat agcgtctctc actgtggctc acccatctgt 224580
          gttgttctcc tcatccattc aggaaatgag attttttttt tttttttttt tttttttttt 224640
          gagacagagt cgcactccat cgcccaggct ggagtgcagt ggctcgatct cggctcactg 224700
          caagctccgc ctccccggtt catgccattt ccctgcctca gcctcccaag tagctgggac 224760
          tacaggcacc cgccaccacg cccggctaat ttttttttaa ttaattaatt tattttttta 224820
          ttgatcattc ttgggtgttt cttgcagagg gggatttggc agggtcatag gacaatagtg 224880
          gagggaaggt cagcagataa acaagtgaac aaaggtctct ggttttccta ggcagaggac 224940
          cctgcggcct tccgcagtgt ttgtgtccct gggtacttga gattagggag tggtgatgac 225000
          tcttaaggag catgctgcct tcaagcatct gtttaacaaa gcacatcttg caccgccctt 225060
          aatccattta accctgagtg gacacagcac atgtttcata gagcacaggg ttgggggtaa 225120
          ggtcacagat caacaggatc ccaaggcaga agaatttttc ttagtacaga acaaaatgaa 225180
          aagtctccca tgtctacttc tttctacaca gacacggcaa ccatctgatt tctcaatctt 225240
          ttccccacct ttcccccttt tctattccac aaagccgcca ttgtcatcat ggcccgttct 225300
          caatgagctg ttgggtacac ctcccagacg gggtggtggc cgggcagagg ggctcctcac 225360
          ttcccagtag gggcggccgg gcagaggcgc ccctctcctc ccggacgggg cggttggctg 225420
          ggcgggggct gaccccccac ctccctcccg gacggggtgg ctgccgggca gagacgctcc 225480
          tcacttccca gacggggtgg ctgcccgacg gaggggctcc tcacttctca gacggggtgg 225540
          ctgcagggcg gagggactcc tcacctccca gacggggtcg cggccgggca gaggctgcag 225600
          tctcggcact ttggggggcc aaggcaggcg gctgggaggt ggaggttgta gcgagccgag 225660
          atcacgccac tgcactgcag cctgggcacc attgagcact gagtgaacga gactccgtct 225720
          gcaatcccgg cacctcggga ggccgaggct ggcagatcac tcgcggttag gagctggaga 225780
          ccagcctggc caacacagcg aaaccccgtc tccaccaaaa aaatacgaaa accagtcagg 225840
          cgtggcagcg cgcgcctgca atcgcaggca ctcggcaggc tgaggcagga gaatcaggca 225900
          gggaggttgc agtgagccga gatggcagca gtacagtcca gcttcggctc ggcatgagag 225960
          ggagaccgtg gaaagagagg gagagggaga ccgtggggag agggagcggg agcgggggag 226020
          ggggaggggg agggttcttt ttctttttta ttattttttg agatagggtc tctgttgctt 226080
          aggctggagt gcagtagcgt aatctcagct cattgcagcc tccacctcct gtatataagc 226140
          aattctcatg ccccagcctc ccatgcagct gggattacag gcatgcacca ccacacccgg 226200
          ctaatttttt tgtgtttttt acatagagac ggggtttcgt catgttggcc aggctggtct 226260
          cgaactcccc acctcaggtg atccgcctgc ctcggcctca caaagtgctg ggattacagg 226320
          catgagccac tgcacccggc cccttttttc tttttaaatc tgccatgggt acagaccaca 226380
          tctttgtgat tctaccttta ggatctgggg gaggaaggaa gggactccca ataatgggat 226440
          gtttgacctc caacggacac tgtaccttca tcccttctcc acaaagaatc cgtagggccg 226500
          tagacagcag cgtctgatgc cgtaaagcct tgcagatggc tccccaagtc catccggact 226560
          catcggtcag ggcgcccagg ctggaaggcc acccagcggg gactgggcct gggcacctgc 226620
          tctcccagct gctttgccct tgtcttgctc cacatggcag gcgtctcaga gaggctcttc 226680
          actgcccttc gcaaaacagc ccagggtggg aaggagaggc tggggtgcag gtcccagctc 226740
          cgtgttgggc tctcaggcag tcccctccct gatgcatctc cttctcggct ctgtctttgc 226800
          cgtgttttcc ttggctggct ttttaaggct agggctatgc aaaaatcctc acttctgaag 226860
          gaagaaatgt ggacagtggg tgaagtttat tcagtaagag gcacttttca ccacagtccc 226920
          tatgctaccc agggaccctt ttaaaaatgg gaataacttt gtttctgcta attgatctac 226980
          atgcttatta tataaaaaaa tgaataaaat agaaaggtgt gctgtagaag gtgaaaatca 227040
          catgcataaa taccaccata tttttagacg ggtggagagg gggagacagc cttgctgggc 227100
          tcctggcagc ctcacattcc cagctgaagg caatgctgtg gccgtgttac ctccttttcc 227160
          ttcctcttct cacttcactg tcaacaaagc atctgacctg caggggggag tggctcgggt 227220
          tttactaaaa acggagtcat gatgctcaga caaaagcgac gttcttcatg tctattttgg 227280
          tttcctttaa gttaagcata gatttttctg gaaaggaccg gagctggctg ttctccctgc 227340
          atggaaaaca acagctcagc gaagcacctg gttttctcaa gttccctgac ctccagcctt 227400
          gctcctgatt cttgatgaca aaacacattc agtgcccttg attgatttag cagagaagtg 227460
          gcaatgctgc cgcatggaac gcagcccatt ctgcctgtga atggaatgcc tcggctgtga 227520
          tggtcttctg ttttgggaaa agattaggtc agttgcagtg ggtcaatgct gagctcggag 227580
          actgaatatc cagccacctt agttcttcct ggtaaaggct atttatctga gccatttatg 227640
          caacccccac cccctgcatt tctccctgca ttcatttctg ccttctgtca tatttgcccc 227700
          ccacactcag gtttttatat ttgttctctt gctcactttg ctgtatcttt aattccattt 227760
          gtcgaacagt ctaagtttta gggtaagaag gagtcacctg gtctaccttt acatggtagg 227820
          acaaggtgcc ccactctgtt caagcaggtt attctgcttt tttttttttt tttttttttt 227880
          tttgagacag agttttgctc gattgcccag gctggagtgc agtggtgcaa tctcagctca 227940
          ctgcagcctc aaactcctgg gctcaagcca tcctcccacc tcagcctccc tagtggttgg 228000
          tactacagac gcatgtcacc atgactggct aatttaaaca attttttttg ttgttgaggc 228060
          caggtgtggt ggctcatgac tgtaatccca gcactttggg aggctgaggc aggtggatca 228120
          cctgagatca agagttcaag accagcctgg caacatggta aaactctgtc tctactaaaa 228180
          atacaaaaat tagctaggcg tggtggtggg cgcctataat cccagctact ctggaggctg 228240
          aggctggaga atcacttgaa cctgggaggc agagtttgca gtgagctgag atcacgccac 228300
          tgcactccag tctgggcaac agagcaagac accatctcaa aaaaaaagaa ttattattat 228360
          tttttttttg tcgagacagg gtttcccggt gttgcctagg ctagtctcaa actcttgggc 228420
          tcaaacaaac ctcccacctc agcttcccaa agtgtgggat tacaggtgtg agctactgcg 228480
          catggtctgt tccactcttt ttggatccta gctgggcctg gaagcccctt cagccccaca 228540
          tctgcaggct gacgttcacc accagcagga ggctttcgtg gcatgtggtc ttacaaacac 228600
          ctctgtgttc aagtcttgaa taagtgactg taagagactc atggagcagg ttgttgccaa 228660
          caccctcccc cactttcttt cttaatttct gcatttttta aaaattaaga tgggatcttg 228720
          gtctactgac taggctggag tgccgtggtg caatcatagc tcactgaagc ctcaaattcc 228780
          tgggctcaaa ttcctgcttc aacctcacaa gtagctggga ccacaggtat aaatattaaa 228840
          tttttttttt tggtagagac agggtctcac tattttgccc aggctggtca tgaccgtttt 228900
          catagcttga atcaaaccag gtttgtgtgt tttctgagat tcctaacatt ttgtttttaa 228960
          gattaaagta ttttagctgg acacggtggc tcatgcctgt aatcccagca ctttgggagg 229020
          ccaaggcggg tggatcgcct gaggtcagga gttcaagacc agcctggcca acatggtgaa 229080
          accccgtcta tactaaaatt acaaaaatta gccaggcgtg gtggcgggca cctgtaatcc 229140
          cagctactcg ggaggctgag gcaggaaaat cgcctgaacc cgggaggcgg aggttgcagc 229200
          gagccaagat tgcgccactg cactccagcc tgggcgacaa gagcaagact ctgtctcaaa 229260
          aaaaaaaaaa aaaaaaaagg atcttattta aagtctctgt ggacaataga tgtccttgct 229320
          tgtgaagaac tggagacatt ggaaattgga actgcagccc cgagtggcca gcccaccaca 229380
          tgccacagtc atggaatcac ccaggtgaga caagtcagcc cttgaatttc caggctgcca 229440
          ttactcacag atgctcactg cctttcaaaa acctagagcc acttccaaat gcttggctgg 229500
          gacttgaaga gaatcatccg tgacatacta gaacgaggtt tcttttaaat gtcaagatgc 229560
          cataaaatga ttcaggccca tccttgaacc ttcagggtga gagctgagca gtcacaagcc 229620
          cctttctggt ctttacatga atcacagaat ttcaaactgg aaggatcctt agaaattcgc 229680
          cttctccaag ttcctgatgt cacagacgtg gagaccaagg gtggaggagg gcagaggctt 229740
          tgctgaaatc tgcaggaatt ggtggcaggt tggggaccat agaatgtgtg tgtgtcttca 229800
          tcctcagtcc aggacccgag tggacccctg gctcggggtc acatgtgtta aacagtagag 229860
          ggtgtgtttt gttctgctgt tttgaggaga aggtgagtct ctttctgctt tgtcagatgg 229920
          aagtctggac aattacttca tagcattcat tcatttgcca cacatattga ttaagggccc 229980
          aatatgggac ccgaactgaa tcactgcagg agactttaga gcgaatattg tctaagacct 230040
          ccaagtctgc ctggctgtga actatcctca gagcgacctg atttaagaat tcagattctg 230100
          gctctcttcc ttggcgctgc ctatggaggg ggcagccatc tcctccttgg catcatggcc 230160
          gccctcagac cccctgtgaa gcccaagatc atcaaaaaga gaaccaagaa gttcatccgg 230220
          caccagtcag accgatgtgt cacgattaag cgtaactggc agaaacccag aggtattgac 230280
          aacagggttg gtagaaggtt caagggccag atcttgatgc ccaacattgg ttatgggagc 230340
          aacaaaaaaa caaagcacac gctgcccact ggcttctgga agttcagtct acaacgtcaa 230400
          ggagctggaa gtgctgctga tgtacaacac ttcttactgc gctgagatcg ctcacagtgt 230460
          ttcctccagg aaccgcgaag ccaccacaga aagagccgcc cagctggcca tcagagtcac 230520
          tgacccccat gccagtctgc gcagtgaaga aaacgagcag acagctcatg tgcatgtttt 230580
          gtgtttaaat aaaactgtaa aaactgcaaa aaaaaaaaaa tgcagattct gaatcccggt 230640
          ctccctgctc cccgatctgg ggctctgggt tggaagctgg gcatcctgaa ttttagtttc 230700
          ctgggcgatt ctgaccacct ggtgggtttg gacttcaacg tgctcactga caccttcgtt 230760
          tagaatttca gatacgaaaa atggatttcc caaggtcaca cacgttatag gtgaggaaac 230820
          tgagtctcac acagattcag tgggctttcc caggtcacag agctagttag ggatgaatgg 230880
          gtttagcgtt gctgcttttc tgtaactgtg acttcctgca agagctgctg gaatgcagct 230940
          gtctacagcc accggaggtg gggagcaagg tgacaaggca gaggacagga gtgattttgt 231000
          tgccttcaga tgagaacggg gtcttcctaa gaccctgcat ccctgaagcc tctgctggta 231060
          actgtgagga tagtctctgc caacagagag ggtgccctga gtttcaatag gagaattggc 231120
          tccatggggt gtaataacca aacgaatgtg cggaatgaca atgatttaat cctgtagcct 231180
          ttattaaagg cttgctttgt gctgggtgag aaaggtctgg gattgtattc ttcattctca 231240
          ttttgaaagg aacacaaatg ccatcaagat tttgatatgg atggccacat gtgtctaagc 231300
          cccggaaaac catcctgaga gatcaagacc atcttggcca ggatggtctt gaactcctga 231360
          cctcatgatc cacccacctc agcctcccaa agtgctggga ttacaggcgt gcaccaccac 231420
          gcctggcctc gttttattct tatttattta tttatttatt tatttatttt tgagatggaa 231480
          tctcactctg tcacccaggc tggaatgcag tggtgtaatc tcggctcact gcaacctctg 231540
          cctcccaggt tccagctctt ctcctgcctc agcctcccga gcagctgaga ctacagacgc 231600
          acgccaccac gcccagctaa tttttgtatt tttattagag acggcgtttc accatgttgg 231660
          ccaggctggt ctcgaactcc tgaactcgtg atccaccctc ctcggcttcc caaagggcta 231720
          ggattatagg cgtgagccac ggtgccctgc ctacatttgg ttttatagtc caccttacac 231780
          agttctctat acattgtaaa tgagccaaat ttcctgaatt gaaaaagaga gtcacacaag 231840
          aggcttgcct ccacgcacag acatgtagtt ttagatgtct gcacgtgaag ctatatcaaa 231900
          ataagaataa actactgcta ccaagaagtg ggaaaaaaat ttaaaaagga taaactgctc 231960
          agaaaacgaa acagattaaa caaaaaattg tattagatga aatttttttt catcgaatct 232020
          tgctccagac tcttcttctg ttgcttcaga cccttcttca tctgaagagt cttgctctgt 232080
          ctcccaggct ggagtgcagt grcacgatct tggcccactg caacctccgc ctcccgggtt 232140
          caagcaattc tcctgcctca gcctcctgag tagctgggat tacaggcgcg caccaccacg 232200
          cccagctaat ttgtgtattt ttagtaggga cggggtttca ccatgttggc caggctggtc 232260
          tcgatctctt gacctcgtga tctgcccgct tcggcctccc aaagtgctgg gattacaggc 232320
          gtgagccacg gcgcccggcc tttcacttgg ttctctatga aaaaattaaa gagaaaatct 232380
          gattgacact gtggaggaca ctacactcca aaaaaaaaag tactatattt tctaatatta 232440
          tcagtgcttt ttaatatttt ctaatattat cagtgaagct tttgccgctt tttcaaaatc 232500
          tggaagaaac aaggcggttg attcctttaa tttcaggagc atgtaacttc atttataatg 232560
          acaatgtttt tgaaaaaata aattaaaccg acagtttcat ttgtaggatt gactttaata 232620
          acacgcctct actgaacaaa tggcgattaa ctggggaaaa cggaattatg gtaaccgagg 232680
          taacggggtc ggggactctt tctccttcgc tgcatgctgg gtggcgggga gagaccgctc 232740
          tgaggaggtt tggtctgtcg gccacgccgt aggccgcggt gcattctggg tcctggcaat 232800
          atggcgtcct ccttgatggg ctgatgagat gagtttcact gtagctccaa accagagggc 232860
          aaagctccca tgacccaata agcccacatt gtccctttcc tccgtggttc cgtgtcgccc 232920
          gtttctcagg actcgttctc aggcaggaga gagcctcggg gctgaaggcc aggaccagcc 232980
          aggccgcgcg gacctgaggt tgaggaaccg ggtgcaggcg agcacgatgg gccggtcgtg 233040
          gctctggttg cagcagctca gacgagtgcg ggacccgcag ggctgagagt ggctggagga 233100
          gacccagggc cctttgaacc cgatcccttg gccggagacc tcagcccagt cggcccagtg 233160
          ggcgaaccgg caccaagagc ggcctgcctg tcttcggaac tgctgaggcg gtggaggccg 233220
          agagcagggt catcgtgagg cctgaagtct cttacgcttt tggcagctcc cctcgcagcc 233280
          cctctggaaa cgtacagcct caggagcagc cagtggcttg ggacctgggg tggtgtgtgt 233340
          ctgcggagct tcttgggctg ccccatttcc tagcggcccc cacctcccca cttcccgctc 233400
          agagttagag ataaggatct cagacttttg cctgagtaag ggtctccgca ctctttatcc 233460
          atttggtttt cgatttcccg tttttgtttc ttatttcacc aattctggta cacgctagtt 233520
          tttaaggctg gaggttctcg agcgcttgct gccaaggact cccccacccc ctcccccact 233580
          gatggagtcc gaaatgctgc aatcgcctct tctgggcctg ggggaggaag atgaggctga 233640
          tcttacagac tggaacctac ctttggcttt tatgaaaaag aggcactgtg agaaaattga 233700
          aggctccaaa tccttagctc agagctggag gatgaaggat cgggtaagtg gattctgaag 233760
          gcaccccttg aacttggtag tttccccaac aaagaaagtt tacagcccga aaagtgtcct 233820
          tgggaaagcg ccgacatttc cccctagcca cacgttgtaa gtcaactaga aagcaaaagc 233880
          catttcagac tgcagttttt ggttgaaaat ggaaaatgct gttttggtta gtcattattc 233940
          actgggtagt gttaattcaa ttccaactaa gttctaattc agataataaa agttaagcaa 234000
          atttgaaaat agagcattgc gagtatttac atgctctttg gcatactact tagttctgta 234060
          aacacttaga ggaaggacaa cgtgcgatat aatctttata cccacatgat tagtctactt 234120
          tttaaaatat ccaagctggg tgaagtgcag aagtctgata tactatgcta ggaaatgaga 234180
          ttactggaaa atgttcaact agtaacaaat tagtgcaaag ttattataaa gttacactga 234240
          acttcattct agtcttctaa acaatttctc ttgaagctag attttcctcc ttttatgtag 234300
          tgtcctgttg ctgtaacttg gaaacaggat ttctttaatc gtgagttagg gtatgaggcg 234360
          tcgagacttg ggtgcaggtt ttagggtgtc cgcatggtgt ttggagtgtg gagagtgact 234420
          cacaagcagc tggtaggaaa gaaaacagcc gaattttgtt ggatttgtcc ttcataaaac 234480
          acccatctat ttcctggcct caaaagcaaa agggtagtac tgcttctcct ctatgcacac 234540
          ttataatttg tctttttgta agttattttc tccctccagg ctgcttttat ttgcacattt 234600
          cagtggtata aaagaggaag ttggtgttac aatgtttgat tttctctagg cttatgtata 234660
          tgtttatgga atattattgt tttttagtat atgatgttga acatatataa gattacactt 234720
          ctgggctggg cgcggtggct cacgcctgta atctcagcac tttgggaggc caaggcaggc 234780
          ctcccaaagg caggcggatc acctgaggtc aggagtttga gaccagcccg gccaacatgg 234840
          tgaaaccctg tctgtactaa aaatacaaaa attagctggg cttggtggca ggtgcccgta 234900
          atcccagcta ctcgagaagc tgaggctgga gaatcgcttg aacctgggag gcagaggttg 234960
          cagtgagccg aaatcgcacc attgcactcc agcctagggg                       235000
Figure 12_A0101_SEQ_0001
Figure 12_A0101_SEQ_0002
Figure 12_A0101_SEQ_0003
Figure 12_A0101_SEQ_0004
Figure 12_A0101_SEQ_0005
Figure 12_A0101_SEQ_0006
Figure 12_A0101_SEQ_0007
Figure 12_A0101_SEQ_0008
Figure 12_A0101_SEQ_0009
Figure 12_A0101_SEQ_0010
Figure 12_A0101_SEQ_0011
Figure 12_A0101_SEQ_0012
Figure 12_A0101_SEQ_0013
Figure 12_A0101_SEQ_0014
Figure 12_A0101_SEQ_0015
Figure 12_A0101_SEQ_0016
Figure 12_A0101_SEQ_0017
Figure 12_A0101_SEQ_0018
Figure 12_A0101_SEQ_0019
Figure 12_A0101_SEQ_0020
Figure 12_A0101_SEQ_0021
Figure 12_A0101_SEQ_0022
Figure 12_A0101_SEQ_0023
Figure 12_A0101_SEQ_0024
Figure 12_A0101_SEQ_0025
Figure 12_A0101_SEQ_0026
Figure 12_A0101_SEQ_0027
Figure 12_A0101_SEQ_0028
Figure 12_A0101_SEQ_0029
Figure 12_A0101_SEQ_0030
Figure 12_A0101_SEQ_0031
Figure 12_A0101_SEQ_0032
Figure 12_A0101_SEQ_0033
Figure 12_A0101_SEQ_0034
Figure 12_A0101_SEQ_0035
Figure 12_A0101_SEQ_0036
Figure 12_A0101_SEQ_0037
Figure 12_A0101_SEQ_0038
Figure 12_A0101_SEQ_0039
Figure 12_A0101_SEQ_0040
Figure 12_A0101_SEQ_0041
Figure 12_A0101_SEQ_0042
Figure 12_A0101_SEQ_0043
Figure 12_A0101_SEQ_0044
Figure 12_A0101_SEQ_0045
Figure 12_A0101_SEQ_0046
Figure 12_A0101_SEQ_0047
Figure 12_A0101_SEQ_0048
Figure 12_A0101_SEQ_0049
Figure 12_A0101_SEQ_0050
Figure 12_A0101_SEQ_0051
Figure 12_A0101_SEQ_0052
Figure 12_A0101_SEQ_0053
Figure 12_A0101_SEQ_0054
Figure 12_A0101_SEQ_0055
Figure 12_A0101_SEQ_0056
Figure 12_A0101_SEQ_0057
Figure 12_A0101_SEQ_0058
Figure 12_A0101_SEQ_0059
Figure 12_A0101_SEQ_0060
Figure 12_A0101_SEQ_0061
Figure 12_A0101_SEQ_0062
Figure 12_A0101_SEQ_0063
Figure 12_A0101_SEQ_0064
Figure 12_A0101_SEQ_0065
Figure 12_A0101_SEQ_0066
Figure 12_A0101_SEQ_0067
Figure 12_A0101_SEQ_0068
Figure 12_A0101_SEQ_0069
Figure 12_A0101_SEQ_0070
Figure 12_A0101_SEQ_0071
Figure 12_A0101_SEQ_0072
Figure 12_A0101_SEQ_0073
Figure 12_A0101_SEQ_0074
Figure 12_A0101_SEQ_0075
Figure 12_A0101_SEQ_0076
Figure 12_A0101_SEQ_0077
Figure 12_A0101_SEQ_0078
Figure 12_A0101_SEQ_0079
Figure 12_A0101_SEQ_0080
Figure 12_A0101_SEQ_0081
Figure 12_A0101_SEQ_0082
Figure 12_A0101_SEQ_0083
Figure 12_A0101_SEQ_0084
Figure 12_A0101_SEQ_0085
Figure 12_A0101_SEQ_0086
Figure 12_A0101_SEQ_0087
Figure 12_A0101_SEQ_0088
Figure 12_A0101_SEQ_0089
Figure 12_A0101_SEQ_0090
Figure 12_A0101_SEQ_0091
Figure 12_A0101_SEQ_0092
Figure 12_A0101_SEQ_0093
Figure 12_A0101_SEQ_0094
Figure 12_A0101_SEQ_0095
Figure 12_A0101_SEQ_0096
Figure 12_A0101_SEQ_0097
Figure 12_A0101_SEQ_0098
Figure 12_A0101_SEQ_0099
Figure 12_A0101_SEQ_0100
Figure 12_A0101_SEQ_0101
Figure 12_A0101_SEQ_0102
Figure 12_A0101_SEQ_0103
Figure 12_A0101_SEQ_0104
Figure 12_A0101_SEQ_0105
Figure 12_A0101_SEQ_0106
Figure 12_A0101_SEQ_0107
Figure 12_A0101_SEQ_0108
Figure 12_A0101_SEQ_0109
Figure 12_A0101_SEQ_0110
Figure 12_A0101_SEQ_0111
Figure 12_A0101_SEQ_0112
Figure 12_A0101_SEQ_0113
Figure 12_A0101_SEQ_0114
Figure 12_A0101_SEQ_0115
Figure 12_A0101_SEQ_0116
Figure 12_A0101_SEQ_0117
Figure 12_A0101_SEQ_0118
Figure 12_A0101_SEQ_0119
Figure 12_A0101_SEQ_0120
Figure 12_A0101_SEQ_0121
Figure 12_A0101_SEQ_0122
Figure 12_A0101_SEQ_0123
Figure 12_A0101_SEQ_0124
Figure 12_A0101_SEQ_0125
Figure 12_A0101_SEQ_0126
Figure 12_A0101_SEQ_0127
Figure 12_A0101_SEQ_0128
Figure 12_A0101_SEQ_0129
Figure 12_A0101_SEQ_0130
Figure 12_A0101_SEQ_0131
Figure 12_A0101_SEQ_0132
Figure 12_A0101_SEQ_0133
Figure 12_A0101_SEQ_0134
Figure 12_A0101_SEQ_0135
Figure 12_A0101_SEQ_0136
Figure 12_A0101_SEQ_0137
Figure 12_A0101_SEQ_0138
Figure 12_A0101_SEQ_0139
Figure 12_A0101_SEQ_0140
Figure 12_A0101_SEQ_0141
Figure 12_A0101_SEQ_0142
Figure 12_A0101_SEQ_0143
Figure 12_A0101_SEQ_0144
Figure 12_A0101_SEQ_0145
Figure 12_A0101_SEQ_0146
Figure 12_A0101_SEQ_0147
Figure 12_A0101_SEQ_0148
Figure 12_A0101_SEQ_0149
Figure 12_A0101_SEQ_0150
Figure 12_A0101_SEQ_0151
Figure 12_A0101_SEQ_0152
Figure 12_A0101_SEQ_0153
Figure 12_A0101_SEQ_0154
Figure 12_A0101_SEQ_0155
Figure 12_A0101_SEQ_0156
Figure 12_A0101_SEQ_0157
Figure 12_A0101_SEQ_0158
Figure 12_A0101_SEQ_0159
Figure 12_A0101_SEQ_0160
Figure 12_A0101_SEQ_0161
Figure 12_A0101_SEQ_0162
Figure 12_A0101_SEQ_0163
Figure 12_A0101_SEQ_0164
Figure 12_A0101_SEQ_0165
Figure 12_A0101_SEQ_0166
Figure 12_A0101_SEQ_0167
Figure 12_A0101_SEQ_0168
Figure 12_A0101_SEQ_0169
Figure 12_A0101_SEQ_0170
Figure 12_A0101_SEQ_0171
Figure 12_A0101_SEQ_0172
Figure 12_A0101_SEQ_0173
Figure 12_A0101_SEQ_0174
Figure 12_A0101_SEQ_0175
Figure 12_A0101_SEQ_0176
Figure 12_A0101_SEQ_0177
Figure 12_A0101_SEQ_0178
Figure 12_A0101_SEQ_0179
Figure 12_A0101_SEQ_0180
Figure 12_A0101_SEQ_0181
Figure 12_A0101_SEQ_0182
Figure 12_A0101_SEQ_0183
Figure 12_A0101_SEQ_0184
Figure 12_A0101_SEQ_0185

Claims (1)

  1. 一種基因標記的用途，其用於製造用於預測大動脈動脈粥樣硬化症的缺血性腦中風發病風險的核苷酸序列，所述基因標記由RNF213 p.R4810K基因多態性組成。
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期刊 Kobayashi, Hatasu, et al. "Biochemical and functional characterization of RNF213 (Mysterin) R4810K, a susceptibility mutation of moyamoya disease, in angiogenesis in vitro and in vivo." Journal of the American Heart Association 4.7 (2015): e002146.

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