CN110914300A - 使用ps靶向抗体与免疫肿瘤学药剂治疗癌症的方法 - Google Patents

使用ps靶向抗体与免疫肿瘤学药剂治疗癌症的方法 Download PDF

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CN110914300A
CN110914300A CN201880023312.0A CN201880023312A CN110914300A CN 110914300 A CN110914300 A CN 110914300A CN 201880023312 A CN201880023312 A CN 201880023312A CN 110914300 A CN110914300 A CN 110914300A
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antibody molecule
antibody
cancer
composition
antibodies
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J.S.肖恩
N.L.卡林特里斯
M.唐
A.F.多尔
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Ankang Leji Co Ltd
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Ankang Leji Co Ltd
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    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A61K38/1761—Apoptosis related proteins, e.g. Apoptotic protease-activating factor-1 (APAF-1), Bax, Bax-inhibitory protein(s)(BI; bax-I), Myeloid cell leukemia associated protein (MCL-1), Inhibitor of apoptosis [IAP] or Bcl-2
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    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
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    • A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C07K16/2827—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
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    • G01N33/57585—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds identifiable in body fluids
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CN201880023312.0A 2017-04-03 2018-04-02 使用ps靶向抗体与免疫肿瘤学药剂治疗癌症的方法 Pending CN110914300A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762481064P 2017-04-03 2017-04-03
US62/481,064 2017-04-03
US201762507545P 2017-05-17 2017-05-17
US62/507,545 2017-05-17
PCT/US2018/025724 WO2018187227A1 (en) 2017-04-03 2018-04-02 Methods for treating cancer using ps-targeting antibodies with immuno-oncology agents

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CN110914300A true CN110914300A (zh) 2020-03-24

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CN201880023312.0A Pending CN110914300A (zh) 2017-04-03 2018-04-02 使用ps靶向抗体与免疫肿瘤学药剂治疗癌症的方法

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US (1) US11571459B2 (https=)
EP (1) EP3606960A1 (https=)
JP (1) JP2020515637A (https=)
KR (1) KR20200020662A (https=)
CN (1) CN110914300A (https=)
AU (1) AU2018249493A1 (https=)
CA (1) CA3055769A1 (https=)
MX (1) MX2019011858A (https=)
WO (1) WO2018187227A1 (https=)

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CN112921091A (zh) * 2021-03-16 2021-06-08 南京先声医学检验有限公司 Flt3基因突变在预测非小细胞肺癌患者对免疫检查点抑制剂疗法敏感性中的应用
CN114288399A (zh) * 2022-01-20 2022-04-08 武汉科技大学 一种嵌合抗原受体联合抗肿瘤药物组合物及其应用
CN114743593A (zh) * 2022-06-13 2022-07-12 北京橡鑫生物科技有限公司 一种基于尿液进行前列腺癌早期筛查模型的构建方法、筛查模型及试剂盒
CN115239156A (zh) * 2022-07-27 2022-10-25 广东省科学院广州地理研究所 城镇化指标对水系结构的影响警示方法

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JP2021502100A (ja) 2017-11-08 2021-01-28 ゼンコア インコーポレイテッド 新規抗ｐｄ−１配列を用いた二重特異性および単一特異性抗体
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TW202019962A (zh) 2018-07-10 2020-06-01 法商賽諾菲公司 標靶CD38及TGF-β的組合療法
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CN114269376A (zh) * 2019-05-03 2022-04-01 豪夫迈·罗氏有限公司 用抗pd-l1抗体治疗癌症的方法
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CN111053900B (zh) * 2019-11-19 2022-05-03 南京大学射阳高新技术研究院 一种靶向肿瘤、提高放疗敏感性的血小板载药体系及其制备方法
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EP4168451A2 (en) 2020-06-22 2023-04-26 NGM Biopharmaceuticals, Inc. Lair-1-binding agents and methods of use thereof
WO2022259247A1 (en) * 2021-06-07 2022-12-15 Cocytus Ltd. Use of death ligands on hematopoietic stem and progenitor cells and mesenchymal stromal cells for cancer therapy
CN113409949B (zh) * 2021-06-26 2022-09-02 南方医科大学南方医院 基于器官转移谱的非小细胞肺癌免疫检查点抑制治疗疗效的预测模型的构建方法及其应用
CN113933517B (zh) * 2021-10-09 2024-02-09 武汉金域医学检验所有限公司 一种检测t细胞对灭活疫苗敏感性的方法
CN114574447B (zh) * 2022-03-10 2023-10-20 中国海洋大学 Her2靶向的增强型抗肿瘤nk细胞、其制备方法及其应用
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