KR20200020662A - 면역-종양학 제제와 함께 ps-표적화 항체를 사용하여 암을 치료하는 방법 - Google Patents
면역-종양학 제제와 함께 ps-표적화 항체를 사용하여 암을 치료하는 방법 Download PDFInfo
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- KR20200020662A KR20200020662A KR1020197028212A KR20197028212A KR20200020662A KR 20200020662 A KR20200020662 A KR 20200020662A KR 1020197028212 A KR1020197028212 A KR 1020197028212A KR 20197028212 A KR20197028212 A KR 20197028212A KR 20200020662 A KR20200020662 A KR 20200020662A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- A61K38/1761—Apoptosis related proteins, e.g. Apoptotic protease-activating factor-1 (APAF-1), Bax, Bax-inhibitory protein(s)(BI; bax-I), Myeloid cell leukemia associated protein (MCL-1), Inhibitor of apoptosis [IAP] or Bcl-2
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- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70596—Molecules with a "CD"-designation not provided for elsewhere
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2818—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2827—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
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- G01N33/57488—
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- G01N33/57492—
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
- G01N33/57585—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds identifiable in body fluids
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
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- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
- G01N33/5759—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds localised on the membrane of tumour or cancer cells
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- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/52—Assays involving cytokines
- G01N2333/555—Interferons [IFN]
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- Chemical & Material Sciences (AREA)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762481064P | 2017-04-03 | 2017-04-03 | |
| US62/481,064 | 2017-04-03 | ||
| US201762507545P | 2017-05-17 | 2017-05-17 | |
| US62/507,545 | 2017-05-17 | ||
| PCT/US2018/025724 WO2018187227A1 (en) | 2017-04-03 | 2018-04-02 | Methods for treating cancer using ps-targeting antibodies with immuno-oncology agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20200020662A true KR20200020662A (ko) | 2020-02-26 |
Family
ID=62116940
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020197028212A Ceased KR20200020662A (ko) | 2017-04-03 | 2018-04-02 | 면역-종양학 제제와 함께 ps-표적화 항체를 사용하여 암을 치료하는 방법 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US11571459B2 (https=) |
| EP (1) | EP3606960A1 (https=) |
| JP (1) | JP2020515637A (https=) |
| KR (1) | KR20200020662A (https=) |
| CN (1) | CN110914300A (https=) |
| AU (1) | AU2018249493A1 (https=) |
| CA (1) | CA3055769A1 (https=) |
| MX (1) | MX2019011858A (https=) |
| WO (1) | WO2018187227A1 (https=) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| KR20190062515A (ko) * | 2016-10-06 | 2019-06-05 | 화이자 인코포레이티드 | 암의 치료를 위한 아벨루맙의 투약 용법 |
| JP2021502100A (ja) | 2017-11-08 | 2021-01-28 | ゼンコア インコーポレイテッド | 新規抗pd−1配列を用いた二重特異性および単一特異性抗体 |
| US20190284553A1 (en) | 2018-03-15 | 2019-09-19 | KSQ Therapeutics, Inc. | Gene-regulating compositions and methods for improved immunotherapy |
| KR20210033947A (ko) * | 2018-06-01 | 2021-03-29 | 예일 유니버시티 | 스테로이드 호르몬-관련된 질환 또는 장애를 치료하기 위한 조성물 및 방법 |
| TW202019962A (zh) | 2018-07-10 | 2020-06-01 | 法商賽諾菲公司 | 標靶CD38及TGF-β的組合療法 |
| US12514853B2 (en) * | 2018-11-20 | 2026-01-06 | Starpharma Pty Ltd. | Therapeutic dendrimer |
| CN114269376A (zh) * | 2019-05-03 | 2022-04-01 | 豪夫迈·罗氏有限公司 | 用抗pd-l1抗体治疗癌症的方法 |
| BR112021024003A2 (pt) * | 2019-05-31 | 2022-04-19 | Alx Oncology Inc | Métodos de tratamento de câncer com fusão sirp alfa-fc em combinação com um inibidor de checkpoint imunológico |
| CN111053900B (zh) * | 2019-11-19 | 2022-05-03 | 南京大学射阳高新技术研究院 | 一种靶向肿瘤、提高放疗敏感性的血小板载药体系及其制备方法 |
| BR112022018238A2 (pt) * | 2020-03-13 | 2022-10-25 | Univ Texas | Método de tratamento de um câncer em um sujeito |
| US20230314438A1 (en) * | 2020-04-03 | 2023-10-05 | University Of Cincinnati | Secreted phosphorylated heat shock protein-70 as a biomarker for treating and diagnosing cancer |
| KR20230009354A (ko) * | 2020-05-12 | 2023-01-17 | 아스트라제네카 아베 | 면역 체크포인트 억제제 항체를 사용한 암 치료용 방법 및 조합물 |
| EP4168451A2 (en) | 2020-06-22 | 2023-04-26 | NGM Biopharmaceuticals, Inc. | Lair-1-binding agents and methods of use thereof |
| CN112921091B (zh) * | 2021-03-16 | 2022-01-21 | 南京先声医学检验实验室有限公司 | Flt3基因突变在预测非小细胞肺癌患者对免疫检查点抑制剂疗法敏感性中的应用 |
| WO2022259247A1 (en) * | 2021-06-07 | 2022-12-15 | Cocytus Ltd. | Use of death ligands on hematopoietic stem and progenitor cells and mesenchymal stromal cells for cancer therapy |
| CN113409949B (zh) * | 2021-06-26 | 2022-09-02 | 南方医科大学南方医院 | 基于器官转移谱的非小细胞肺癌免疫检查点抑制治疗疗效的预测模型的构建方法及其应用 |
| CN113933517B (zh) * | 2021-10-09 | 2024-02-09 | 武汉金域医学检验所有限公司 | 一种检测t细胞对灭活疫苗敏感性的方法 |
| CN114288399B (zh) * | 2022-01-20 | 2023-10-27 | 武汉科技大学 | 一种嵌合抗原受体联合抗肿瘤药物组合物及其应用 |
| CN114574447B (zh) * | 2022-03-10 | 2023-10-20 | 中国海洋大学 | Her2靶向的增强型抗肿瘤nk细胞、其制备方法及其应用 |
| CN114793959B (zh) * | 2022-05-06 | 2023-03-14 | 昆明市水产科学研究所 | 一种提高产后亲鱼成活率的银白鱼人工繁殖方法 |
| CN114743593B (zh) * | 2022-06-13 | 2023-02-24 | 北京橡鑫生物科技有限公司 | 一种基于尿液进行前列腺癌早期筛查模型的构建方法、筛查模型及试剂盒 |
| CN115239156B (zh) * | 2022-07-27 | 2023-08-29 | 广东省科学院广州地理研究所 | 一种城镇化指标对水系结构的影响警示方法和装置 |
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| DE4122599C2 (de) | 1991-07-08 | 1993-11-11 | Deutsches Krebsforsch | Phagemid zum Screenen von Antikörpern |
| AU701578B2 (en) | 1992-08-21 | 1999-02-04 | Vrije Universiteit Brussel | Immunoglobulins devoid of light chains |
| US5731168A (en) | 1995-03-01 | 1998-03-24 | Genentech, Inc. | Method for making heteromultimeric polypeptides |
| US5811097A (en) | 1995-07-25 | 1998-09-22 | The Regents Of The University Of California | Blockade of T lymphocyte down-regulation associated with CTLA-4 signaling |
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-
2018
- 2018-04-02 JP JP2020502539A patent/JP2020515637A/ja active Pending
- 2018-04-02 CN CN201880023312.0A patent/CN110914300A/zh active Pending
- 2018-04-02 WO PCT/US2018/025724 patent/WO2018187227A1/en not_active Ceased
- 2018-04-02 KR KR1020197028212A patent/KR20200020662A/ko not_active Ceased
- 2018-04-02 CA CA3055769A patent/CA3055769A1/en not_active Abandoned
- 2018-04-02 US US15/943,304 patent/US11571459B2/en active Active
- 2018-04-02 MX MX2019011858A patent/MX2019011858A/es unknown
- 2018-04-02 EP EP18723091.7A patent/EP3606960A1/en active Pending
- 2018-04-02 AU AU2018249493A patent/AU2018249493A1/en not_active Abandoned
Also Published As
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|---|---|
| WO2018187227A8 (en) | 2018-11-15 |
| WO2018187227A1 (en) | 2018-10-11 |
| JP2020515637A (ja) | 2020-05-28 |
| AU2018249493A1 (en) | 2019-09-19 |
| EP3606960A1 (en) | 2020-02-12 |
| MX2019011858A (es) | 2019-11-21 |
| US11571459B2 (en) | 2023-02-07 |
| CN110914300A (zh) | 2020-03-24 |
| US20180289771A1 (en) | 2018-10-11 |
| CA3055769A1 (en) | 2018-10-11 |
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