CN110494181B - 用于输送干粉药物的装置和方法 - Google Patents

用于输送干粉药物的装置和方法 Download PDF

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Publication number
CN110494181B
CN110494181B CN201880020954.5A CN201880020954A CN110494181B CN 110494181 B CN110494181 B CN 110494181B CN 201880020954 A CN201880020954 A CN 201880020954A CN 110494181 B CN110494181 B CN 110494181B
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CN
China
Prior art keywords
chamber
dry powder
intake
exit
inlet
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Expired - Fee Related
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CN201880020954.5A
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English (en)
Chinese (zh)
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CN110494181A (zh
Inventor
E·C·理查森
小吉尔伯特·S·摩特
W·J·亚历山大
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Concentrx Pharmaceuticals Inc
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Concentrx Pharmaceuticals Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0086—Inhalation chambers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0005—Details of inhalators; Constructional features thereof with means for agitating the medicament
    • A61M15/0006—Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means
    • A61M15/0008—Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means rotating by airflow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/002—Details of inhalators; Constructional features thereof with air flow regulating means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0043—Non-destructive separation of the package, e.g. peeling
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/583—Means for facilitating use, e.g. by people with impaired vision by visual feedback
    • A61M2205/584—Means for facilitating use, e.g. by people with impaired vision by visual feedback having a color code
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00—Characteristics of a physical parameter; associated device therefor
    • A61M2206/10—Flow characteristics
    • A61M2206/16—Rotating swirling helical flow, e.g. by tangential inflows
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00—Characteristics of a physical parameter; associated device therefor
    • A61M2206/10—Flow characteristics
    • A61M2206/20—Flow characteristics having means for promoting or enhancing the flow, actively or passively
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2209/00—Ancillary equipment
    • A61M2209/06—Packaging for specific medical equipment

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Otolaryngology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201880020954.5A 2017-03-28 2018-03-28 用于输送干粉药物的装置和方法 Expired - Fee Related CN110494181B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762477506P 2017-03-28 2017-03-28
US62/477,506 2017-03-28
PCT/US2018/024882 WO2018183528A1 (en) 2017-03-28 2018-03-28 Devices and methods for delivering dry powder medicaments

Publications (2)

Publication Number Publication Date
CN110494181A CN110494181A (zh) 2019-11-22
CN110494181B true CN110494181B (zh) 2022-03-18

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Family Applications (1)

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CN201880020954.5A Expired - Fee Related CN110494181B (zh) 2017-03-28 2018-03-28 用于输送干粉药物的装置和方法

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US (4) US10456537B2 (https=)
EP (1) EP3600504B1 (https=)
JP (1) JP2020515366A (https=)
CN (1) CN110494181B (https=)
AU (1) AU2018244582A1 (https=)
CA (1) CA3057683A1 (https=)
WO (1) WO2018183528A1 (https=)

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EP2747815B1 (en) 2011-09-07 2017-11-29 Concentrx Pharmaceuticals, Inc. Dry powder inhalation device
DE102014005647B4 (de) * 2014-01-30 2016-05-12 Klaus-Dieter Beller Pulverinhalator und Pulverinhalatorset
DE102014005646B4 (de) * 2014-01-30 2016-05-12 Klaus-Dieter Beller Pulverinhalator und Pulverinhalationsset
AU2018244582A1 (en) 2017-03-28 2019-09-19 Concentrx Pharmaceuticals, Inc. Devices and methods for delivering dry powder medicaments
US10543499B1 (en) * 2018-03-13 2020-01-28 Karriem Cherry Disposable powder-dispensing bulb
IT202000005698A1 (it) * 2020-03-17 2021-09-17 Everest Group Holding Sa Dispositivo per l’inalazione di acido acetilsalicilico in polvere e suo uso relativo
EP4204048B1 (en) * 2020-08-25 2024-10-09 Vectura Delivery Devices Limited Unit dose dry powder inhaler
CN115554536A (zh) * 2022-11-09 2023-01-03 苏州易合医药有限公司 单剂量干粉吸入装置
WO2025056344A1 (en) * 2023-09-11 2025-03-20 Iconovo Ab A dry-powder nasal inhaler comprising a casing with a first casing portion and a second casing portion

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Publication number Publication date
US20200108212A1 (en) 2020-04-09
US10456537B2 (en) 2019-10-29
JP2020515366A (ja) 2020-05-28
CA3057683A1 (en) 2018-10-04
CN110494181A (zh) 2019-11-22
US20180280639A1 (en) 2018-10-04
EP3600504B1 (en) 2023-07-12
US20220143334A1 (en) 2022-05-12
US11185647B2 (en) 2021-11-30
US20240316292A1 (en) 2024-09-26
EP3600504A4 (en) 2020-12-30
US11911560B2 (en) 2024-02-27
AU2018244582A1 (en) 2019-09-19
WO2018183528A1 (en) 2018-10-04
EP3600504A1 (en) 2020-02-05
EP3600504C0 (en) 2023-07-12

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