AU2018244582A1 - Devices and methods for delivering dry powder medicaments - Google Patents
Devices and methods for delivering dry powder medicaments Download PDFInfo
- Publication number
- AU2018244582A1 AU2018244582A1 AU2018244582A AU2018244582A AU2018244582A1 AU 2018244582 A1 AU2018244582 A1 AU 2018244582A1 AU 2018244582 A AU2018244582 A AU 2018244582A AU 2018244582 A AU2018244582 A AU 2018244582A AU 2018244582 A1 AU2018244582 A1 AU 2018244582A1
- Authority
- AU
- Australia
- Prior art keywords
- chamber
- disaggregation
- dry powder
- exit
- intake
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 239000000843 powder Substances 0.000 title claims abstract description 175
- 238000000034 method Methods 0.000 title claims description 65
- 239000003814 drug Substances 0.000 title description 234
- 230000007704 transition Effects 0.000 claims abstract description 43
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- 239000008101 lactose Substances 0.000 claims description 40
- 239000010419 fine particle Substances 0.000 claims description 30
- 230000004888 barrier function Effects 0.000 claims description 28
- 229940112141 dry powder inhaler Drugs 0.000 claims description 28
- 239000012530 fluid Substances 0.000 claims description 19
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- 230000008878 coupling Effects 0.000 claims description 10
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- KVNRKLOLUZSPOE-UHFFFAOYSA-M 4-[2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol;(8-methyl-8-propan-2-yl-8-azoniabicyclo[3.2.1]octan-3-yl) 3-hydroxy-2-phenylpropanoate;sulfuric acid;bromide Chemical compound [Br-].OS(O)(=O)=O.CC(C)(C)NCC(O)C1=CC=C(O)C(CO)=C1.CC(C)(C)NCC(O)C1=CC=C(O)C(CO)=C1.CC(C)[N+]1(C)C(C2)CCC1CC2OC(=O)C(CO)C1=CC=CC=C1 KVNRKLOLUZSPOE-UHFFFAOYSA-M 0.000 claims description 8
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- RATSWNOMCHFQGJ-XODSYJLDSA-N (e)-but-2-enedioic acid;n-[2-hydroxy-5-[1-hydroxy-2-[1-(4-methoxyphenyl)propan-2-ylamino]ethyl]phenyl]formamide;dihydrate Chemical compound O.O.OC(=O)\C=C\C(O)=O.C1=CC(OC)=CC=C1CC(C)NCC(O)C1=CC=C(O)C(NC=O)=C1.C1=CC(OC)=CC=C1CC(C)NCC(O)C1=CC=C(O)C(NC=O)=C1 RATSWNOMCHFQGJ-XODSYJLDSA-N 0.000 description 3
- 229910018173 Al—Al Inorganic materials 0.000 description 3
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- FVTWTVQXNAJTQP-UHFFFAOYSA-N diphenyl-[1-(2-phenylmethoxyethyl)-1-azoniabicyclo[2.2.2]octan-4-yl]methanol Chemical compound C=1C=CC=CC=1C(C12CC[N+](CCOCC=3C=CC=CC=3)(CC1)CC2)(O)C1=CC=CC=C1 FVTWTVQXNAJTQP-UHFFFAOYSA-N 0.000 description 3
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- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 description 1
- 239000000932 sedative agent Substances 0.000 description 1
- 230000001624 sedative effect Effects 0.000 description 1
- 239000002002 slurry Substances 0.000 description 1
- IGRAQVLKCQVBQA-DBQHITQZSA-M sodium;butanedioic acid;1-[3-[2-(dimethylamino)ethyl]-1h-indol-5-yl]-n-methylmethanesulfonamide;(2s)-2-(6-methoxynaphthalen-2-yl)propanoate Chemical compound [Na+].OC(=O)CCC(O)=O.C1=C([C@H](C)C([O-])=O)C=CC2=CC(OC)=CC=C21.CNS(=O)(=O)CC1=CC=C2NC=C(CCN(C)C)C2=C1 IGRAQVLKCQVBQA-DBQHITQZSA-M 0.000 description 1
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- 229960005322 streptomycin Drugs 0.000 description 1
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- HUNXMJYCHXQEGX-UHFFFAOYSA-N zaleplon Chemical compound CCN(C(C)=O)C1=CC=CC(C=2N3N=CC(=C3N=CC=2)C#N)=C1 HUNXMJYCHXQEGX-UHFFFAOYSA-N 0.000 description 1
- 229960004010 zaleplon Drugs 0.000 description 1
- ARAIBEBZBOPLMB-UFGQHTETSA-N zanamivir Chemical compound CC(=O)N[C@@H]1[C@@H](N=C(N)N)C=C(C(O)=O)O[C@H]1[C@H](O)[C@H](O)CO ARAIBEBZBOPLMB-UFGQHTETSA-N 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0086—Inhalation chambers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0005—Details of inhalators; Constructional features thereof with means for agitating the medicament
- A61M15/0006—Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means
- A61M15/0008—Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means rotating by airflow
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/002—Details of inhalators; Constructional features thereof with air flow regulating means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
- A61M15/0043—Non-destructive separation of the package, e.g. peeling
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0021—Mouthpieces therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/064—Powder
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
- A61M2205/583—Means for facilitating use, e.g. by people with impaired vision by visual feedback
- A61M2205/584—Means for facilitating use, e.g. by people with impaired vision by visual feedback having a color code
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2206/00—Characteristics of a physical parameter; associated device therefor
- A61M2206/10—Flow characteristics
- A61M2206/16—Rotating swirling helical flow, e.g. by tangential inflows
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2206/00—Characteristics of a physical parameter; associated device therefor
- A61M2206/10—Flow characteristics
- A61M2206/20—Flow characteristics having means for promoting or enhancing the flow, actively or passively
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2209/00—Ancillary equipment
- A61M2209/06—Packaging for specific medical equipment
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Pulmonology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Anesthesiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Otolaryngology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762477506P | 2017-03-28 | 2017-03-28 | |
| US62/477,506 | 2017-03-28 | ||
| PCT/US2018/024882 WO2018183528A1 (en) | 2017-03-28 | 2018-03-28 | Devices and methods for delivering dry powder medicaments |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2018244582A1 true AU2018244582A1 (en) | 2019-09-19 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2018244582A Abandoned AU2018244582A1 (en) | 2017-03-28 | 2018-03-28 | Devices and methods for delivering dry powder medicaments |
Country Status (7)
| Country | Link |
|---|---|
| US (4) | US10456537B2 (https=) |
| EP (1) | EP3600504B1 (https=) |
| JP (1) | JP2020515366A (https=) |
| CN (1) | CN110494181B (https=) |
| AU (1) | AU2018244582A1 (https=) |
| CA (1) | CA3057683A1 (https=) |
| WO (1) | WO2018183528A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2747815B1 (en) | 2011-09-07 | 2017-11-29 | Concentrx Pharmaceuticals, Inc. | Dry powder inhalation device |
| DE102014005647B4 (de) * | 2014-01-30 | 2016-05-12 | Klaus-Dieter Beller | Pulverinhalator und Pulverinhalatorset |
| DE102014005646B4 (de) * | 2014-01-30 | 2016-05-12 | Klaus-Dieter Beller | Pulverinhalator und Pulverinhalationsset |
| AU2018244582A1 (en) | 2017-03-28 | 2019-09-19 | Concentrx Pharmaceuticals, Inc. | Devices and methods for delivering dry powder medicaments |
| US10543499B1 (en) * | 2018-03-13 | 2020-01-28 | Karriem Cherry | Disposable powder-dispensing bulb |
| IT202000005698A1 (it) * | 2020-03-17 | 2021-09-17 | Everest Group Holding Sa | Dispositivo per l’inalazione di acido acetilsalicilico in polvere e suo uso relativo |
| EP4204048B1 (en) * | 2020-08-25 | 2024-10-09 | Vectura Delivery Devices Limited | Unit dose dry powder inhaler |
| CN115554536A (zh) * | 2022-11-09 | 2023-01-03 | 苏州易合医药有限公司 | 单剂量干粉吸入装置 |
| WO2025056344A1 (en) * | 2023-09-11 | 2025-03-20 | Iconovo Ab | A dry-powder nasal inhaler comprising a casing with a first casing portion and a second casing portion |
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| DK2712643T3 (en) | 2012-09-26 | 2018-06-14 | Boehringer Ingelheim Int | INHALER |
| JP6543620B2 (ja) | 2013-10-07 | 2019-07-10 | テバ ブランデッド ファーマシューティカル プロダクツ アール アンド ディー インコーポレイテッド | ドライパウダー吸入器 |
| SE538667C2 (sv) | 2013-12-23 | 2016-10-11 | Iconovo Ab | Enkeldostorrpulverinhalator |
| DE102014005647B4 (de) * | 2014-01-30 | 2016-05-12 | Klaus-Dieter Beller | Pulverinhalator und Pulverinhalatorset |
| US11147936B2 (en) | 2014-05-02 | 2021-10-19 | Manta Devices, Llc | Dose delivery device with cover connected to dose chamber seal |
| CN106470723B (zh) | 2014-06-06 | 2019-12-13 | 格罗宁根大学 | 呼吸启动的干粉吸入器 |
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| SE539111C2 (en) | 2015-06-03 | 2017-04-11 | Iconovo Ab | Single dose dry powder inhaler |
| AU2018244582A1 (en) | 2017-03-28 | 2019-09-19 | Concentrx Pharmaceuticals, Inc. | Devices and methods for delivering dry powder medicaments |
| DE102017006763A1 (de) | 2017-07-18 | 2019-01-24 | Klaus Dieter Beller | Einzeldosis-Pulverinhalator |
| CN111065429A (zh) | 2017-09-19 | 2020-04-24 | 艾克诺韦公司 | 一种其壳体包括第一壳部和第二壳部的干粉吸入器 |
-
2018
- 2018-03-28 AU AU2018244582A patent/AU2018244582A1/en not_active Abandoned
- 2018-03-28 CA CA3057683A patent/CA3057683A1/en active Pending
- 2018-03-28 CN CN201880020954.5A patent/CN110494181B/zh not_active Expired - Fee Related
- 2018-03-28 US US15/938,766 patent/US10456537B2/en active Active
- 2018-03-28 WO PCT/US2018/024882 patent/WO2018183528A1/en not_active Ceased
- 2018-03-28 JP JP2020502516A patent/JP2020515366A/ja active Pending
- 2018-03-28 EP EP18776448.5A patent/EP3600504B1/en active Active
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2019
- 2019-10-10 US US16/598,648 patent/US11185647B2/en not_active Expired - Fee Related
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2021
- 2021-11-16 US US17/527,290 patent/US11911560B2/en active Active
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2024
- 2024-01-19 US US18/417,046 patent/US20240316292A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20200108212A1 (en) | 2020-04-09 |
| US10456537B2 (en) | 2019-10-29 |
| JP2020515366A (ja) | 2020-05-28 |
| CA3057683A1 (en) | 2018-10-04 |
| CN110494181A (zh) | 2019-11-22 |
| US20180280639A1 (en) | 2018-10-04 |
| EP3600504B1 (en) | 2023-07-12 |
| US20220143334A1 (en) | 2022-05-12 |
| US11185647B2 (en) | 2021-11-30 |
| US20240316292A1 (en) | 2024-09-26 |
| CN110494181B (zh) | 2022-03-18 |
| EP3600504A4 (en) | 2020-12-30 |
| US11911560B2 (en) | 2024-02-27 |
| WO2018183528A1 (en) | 2018-10-04 |
| EP3600504A1 (en) | 2020-02-05 |
| EP3600504C0 (en) | 2023-07-12 |
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