CN110464720A - 一种具有防治肠易激综合征的蝉蜕乙酰多巴胺多聚体组合物及其应用 - Google Patents
一种具有防治肠易激综合征的蝉蜕乙酰多巴胺多聚体组合物及其应用 Download PDFInfo
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- CN110464720A CN110464720A CN201910797530.6A CN201910797530A CN110464720A CN 110464720 A CN110464720 A CN 110464720A CN 201910797530 A CN201910797530 A CN 201910797530A CN 110464720 A CN110464720 A CN 110464720A
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- Prior art keywords
- cicada slough
- acetyldopamine
- bowel syndrome
- irritable bowel
- polymer composition
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
- A61K31/36—Compounds containing methylenedioxyphenyl groups, e.g. sesamin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Description
组别 | AWR/分 |
空白对照组 | 1.42±0.13** |
模型对照组 | 3.98±0.16 |
马来酸曲美布汀 | 1.79±0.59** |
蝉蜕乙酰多巴胺多聚体组合物低剂量组 | 3.24±0.65 |
蝉蜕乙酰多巴胺多聚体组合物中剂量组 | 1.46±0.26** |
蝉蜕乙酰多巴胺多聚体组合物高剂量组 | 1.32±0.17** |
Claims (6)
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CN201910797530.6A CN110464720B (zh) | 2019-08-27 | 2019-08-27 | 一种具有防治肠易激综合征的蝉蜕乙酰多巴胺多聚体组合物及其应用 |
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CN201910797530.6A CN110464720B (zh) | 2019-08-27 | 2019-08-27 | 一种具有防治肠易激综合征的蝉蜕乙酰多巴胺多聚体组合物及其应用 |
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CN110464720A true CN110464720A (zh) | 2019-11-19 |
CN110464720B CN110464720B (zh) | 2022-06-28 |
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Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102285958A (zh) * | 2011-04-21 | 2011-12-21 | 李国玉 | 一组多巴胺多聚体和其衍生物及其制备方法和医药用途 |
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2019
- 2019-08-27 CN CN201910797530.6A patent/CN110464720B/zh active Active
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102285958A (zh) * | 2011-04-21 | 2011-12-21 | 李国玉 | 一组多巴胺多聚体和其衍生物及其制备方法和医药用途 |
Non-Patent Citations (3)
Title |
---|
LU YANG等: "Two new N-acetyldopamine tetrapolymers from Periostracum Cicadae", 《JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH》 * |
MING-ZHE XU等: "Antioxidant and anti-inflammatory activities of N-acetyldopamine dimers from Periostracum Cicadae", 《BIOORGANIC & MEDICINAL CHEMISTRY》 * |
杨璐等: "蝉蜕中乙酰多巴胺二聚体超高效液相色谱法多组分测定及其在药材中的分布", 《沈阳药科大学学报》 * |
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Effective date of registration: 20220225 Address after: 300410 2 East Road Puji River, Beichen District, Tianjin (Tsun Li modern Chinese medicine city) Applicant after: TASLY PHARMACEUTICAL GROUP Co.,Ltd. Address before: 210028, cross street, Hongshan Road, Jiangsu, Nanjing, 100 Applicant before: JIANGSU PROVINCE INSTITUTE OF TRADITIONAL CHINESE MEDICINE |
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Effective date of registration: 20240502 Address after: 300410 2 East Road Puji River, Beichen District, Tianjin (Tsun Li modern Chinese medicine city) Patentee after: TASLY PHARMACEUTICAL GROUP Co.,Ltd. Country or region after: China Patentee after: Tianjin Tasly Modern TCM Resources Co.,Ltd. Address before: 300410 2 East Road Puji River, Beichen District, Tianjin (Tsun Li modern Chinese medicine city) Patentee before: TASLY PHARMACEUTICAL GROUP Co.,Ltd. Country or region before: China |