CN110366557B - 结合多肽及其制备方法 - Google Patents

结合多肽及其制备方法 Download PDF

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Publication number
CN110366557B
CN110366557B CN201780086589.3A CN201780086589A CN110366557B CN 110366557 B CN110366557 B CN 110366557B CN 201780086589 A CN201780086589 A CN 201780086589A CN 110366557 B CN110366557 B CN 110366557B
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cell
cdna
sequence
chain
encoding
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Chinese (zh)
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CN110366557A (zh
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Z·西里瓦
G·巴布考克
L·罗宾森
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Visterra Inc
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Visterra Inc
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1093General methods of preparing gene libraries, not provided for in other subgroups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/005Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies constructed by phage libraries
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/10Immunoglobulins specific features characterized by their source of isolation or production
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622Single chain antibody (scFv)

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Physics & Mathematics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CN201780086589.3A 2016-12-23 2017-12-22 结合多肽及其制备方法 Active CN110366557B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662438712P 2016-12-23 2016-12-23
US62/438,712 2016-12-23
PCT/US2017/068204 WO2018119402A1 (en) 2016-12-23 2017-12-22 Binding polypeptides and methods of making the same

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CN110366557A CN110366557A (zh) 2019-10-22
CN110366557B true CN110366557B (zh) 2024-04-09

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US (2) US11820979B2 (https=)
EP (1) EP3559028A1 (https=)
JP (2) JP7360324B2 (https=)
KR (2) KR102702552B1 (https=)
CN (1) CN110366557B (https=)
AU (1) AU2017382367B2 (https=)
BR (1) BR112019013096A2 (https=)
CA (1) CA3045696A1 (https=)
CL (2) CL2019001757A1 (https=)
CO (1) CO2019006663A2 (https=)
IL (2) IL315727A (https=)
MX (1) MX2019007356A (https=)
MY (1) MY201744A (https=)
RU (1) RU2019123063A (https=)
WO (1) WO2018119402A1 (https=)

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EP3781677A4 (en) * 2018-04-16 2022-01-19 University of Massachusetts COMPOSITIONS AND METHODS FOR IMPROVED GENE EDITTING
CN109161572B (zh) * 2018-07-05 2021-11-12 中国海洋大学 单链环状核酸及其制备方法和应用
WO2020097395A1 (en) 2018-11-08 2020-05-14 The Regents Of The University Of California Systems and methods for targeting cancer cells

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Publication number Publication date
JP7360324B2 (ja) 2023-10-12
CN110366557A (zh) 2019-10-22
US11820979B2 (en) 2023-11-21
WO2018119402A1 (en) 2018-06-28
JP2023169422A (ja) 2023-11-29
KR20240133790A (ko) 2024-09-04
CO2019006663A2 (es) 2019-06-28
AU2017382367B2 (en) 2024-11-21
CA3045696A1 (en) 2018-06-28
IL267565A (en) 2019-08-29
US20180201926A1 (en) 2018-07-19
KR102702552B1 (ko) 2024-09-03
MY201744A (en) 2024-03-15
JP2020511117A (ja) 2020-04-16
RU2019123063A (ru) 2021-01-26
CL2019001757A1 (es) 2019-11-29
KR20190111036A (ko) 2019-10-01
IL267565B1 (en) 2024-10-01
US20240141334A1 (en) 2024-05-02
RU2019123063A3 (https=) 2021-11-29
MX2019007356A (es) 2019-09-05
IL267565B2 (en) 2025-02-01
AU2017382367A1 (en) 2019-06-13
EP3559028A1 (en) 2019-10-30
IL315727A (en) 2024-11-01
BR112019013096A2 (pt) 2019-12-17
CL2022000454A1 (es) 2023-03-24

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