CN110300581B - 具有奇数碳的脂类化合物及其作为医药组合物或者营养补充剂的用途 - Google Patents

具有奇数碳的脂类化合物及其作为医药组合物或者营养补充剂的用途 Download PDF

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CN110300581B
CN110300581B CN201780036000.9A CN201780036000A CN110300581B CN 110300581 B CN110300581 B CN 110300581B CN 201780036000 A CN201780036000 A CN 201780036000A CN 110300581 B CN110300581 B CN 110300581B
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CN110300581A (zh
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董宇红
张俊雄
林胜堂
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Sunregen Healthcare AG
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CN201780036000.9A 2016-06-08 2017-06-06 具有奇数碳的脂类化合物及其作为医药组合物或者营养补充剂的用途 Active CN110300581B (zh)

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CN202311053636.8A CN117298092A (zh) 2016-06-08 2017-06-06 具有奇数碳的脂类化合物及其作为医药组合物或者营养补充剂的用途

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US201662347103P 2016-06-08 2016-06-08
US62/347,103 2016-06-08
PCT/CN2017/087341 WO2017211274A1 (en) 2016-06-08 2017-06-06 Lipids with odd number of carbon atoms and their use as pharmaceutical composition or nutritional supplement

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CN202311053636.8A Pending CN117298092A (zh) 2016-06-08 2017-06-06 具有奇数碳的脂类化合物及其作为医药组合物或者营养补充剂的用途

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US (2) US11406616B2 (https=)
EP (1) EP3468551A4 (https=)
JP (2) JP6872805B2 (https=)
KR (1) KR20190017873A (https=)
CN (2) CN110300581B (https=)
AU (1) AU2017277005B2 (https=)
CL (1) CL2018003537A1 (https=)
MX (1) MX2018015188A (https=)
NZ (1) NZ749389A (https=)
SG (1) SG11201810580PA (https=)
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WO2019052629A1 (en) * 2017-09-12 2019-03-21 Sunregen Healthcare Ag LIPIDS HAVING AN IMPERATIVE NUMBER OF CARBON ATOMS AND THEIR USE AS A PHARMACEUTICAL COMPOSITION OR FOOD SUPPLEMENT
CN111773274A (zh) * 2019-09-20 2020-10-16 厦门医学院 瓶尔小草及车前子组合物在制备降血糖及降血压的药物组合物中的应用
CN111773351A (zh) * 2019-09-20 2020-10-16 厦门医学院 瓶尔小草及姜黄组合物在制备降血糖及降血压的药物组合物中的应用
JP7685134B2 (ja) * 2019-11-27 2025-05-29 リファインホールディングス株式会社 インスリン分泌促進剤並びにこれを用いた血糖値改善剤、糖尿病改善剤及び食品
WO2022263624A1 (en) * 2021-06-18 2022-12-22 Sunregen Healthcare Ag Novel compounds for the treatment and prevention of neurological complications of viral infections
JP2023061448A (ja) * 2021-10-20 2023-05-02 リファインホールディングス株式会社 小胞体ストレス抑制剤、神経変性疾患予防改善剤および認知症の予防・進行防止・改善剤、並びに食品
JPWO2024075625A1 (https=) * 2022-10-02 2024-04-11

Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1309642A (zh) * 1998-05-11 2001-08-22 德雷斯顿药品工厂有限公司 具有止喘、抗变态反应、抗炎、免疫调节和神经保护作用的新的1,2,5－三取代1,2－二氢吲唑－3－酮类化合物、其制备方法以及作为药物的应用
JP2005089375A (ja) * 2003-09-18 2005-04-07 Noevir Co Ltd 細胞賦活剤、美白剤、及び抗酸化剤
CN1764446A (zh) * 2003-03-13 2006-04-26 康福玛医药公司 含有长链和中链甘油三酯的药物制剂
CN101137369A (zh) * 2005-02-09 2008-03-05 马库赛特公司 用于眼治疗的制剂
DE102008046227A1 (de) * 2008-06-10 2009-12-17 Ludwig-Maximilians-Universität München Hochdurchsatzmethode zur Analyse der Fettsäurezusammensetzung in Plasmaphosphoglyceriden
CN102215839A (zh) * 2008-11-18 2011-10-12 贝朗医疗有限公司 用于人工喂养重病的重症特护患者的脂肪乳剂
CN102781438A (zh) * 2009-12-30 2012-11-14 贝勒研究院 用于阿尔茨海默病和脑衰老的补给疗法
CN102821602A (zh) * 2010-01-08 2012-12-12 凯特贝希制药公司 脂肪酸富马酸酯衍生物及其用途
CN102883733A (zh) * 2010-02-10 2013-01-16 奥力榨油化株式会社 Age生成抑制剂
CN103096876A (zh) * 2010-07-15 2013-05-08 海布里詹尼克斯股份公司 维生素d的14-差向异构-类似物的制剂
CN103641713A (zh) * 2013-11-15 2014-03-19 浙江大学 甘油单酯衍生物的制备方法及应用
CN105267501A (zh) * 2015-11-04 2016-01-27 夏茂森 一种治疗毒蛇咬伤的中药组合物

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS558351A (en) 1978-07-05 1980-01-21 Hitachi Ltd Press machine
DE3032300A1 (de) 1980-08-27 1982-04-01 Alfred Ing. Wien Lohninger Mittel zur parenteralen ernaehrung
JPS5919775U (ja) 1982-07-26 1984-02-06 ワイケイケイ株式会社 カ−テンウオ−ルの断熱窓
CA1244772A (en) 1983-06-21 1988-11-15 Kuniaki Adachi Cell-stimulating composition
JPH02247125A (ja) 1989-03-17 1990-10-02 Koken Kk 悪性腫瘍細胞増殖抑制剤
JP3558351B2 (ja) 1992-12-07 2004-08-25 邦郎 辻 免疫抑制剤
AU2001257451A1 (en) 2000-05-01 2001-11-12 Accera, Inc. Use of medium chain triglycerides for the treatment and prevention of alzheimer's disease and other diseases resulting from reduced neuronal metabolism
AU2001264079A1 (en) 2000-06-14 2001-12-24 William Leslie Porter Lipids for modulating immune response
IL142535A0 (en) * 2001-04-11 2002-03-10 Yeda Res & Dev Pharmaceutical compositions for the treatment of inflammation
IL158322A0 (en) 2001-04-18 2004-05-12 Prometic Biosciences Inc Medium-chain length fatty acids, glycerides and analogues as neutrophil survival and activation factors
US8399515B2 (en) 2003-05-20 2013-03-19 Baylor Research Institute Five and fifteen carbon fatty acids for treating metabolic disorders and as nutritional supplements
WO2005018632A1 (en) 2003-08-18 2005-03-03 Btg International Limited Treatment of neurodegenerative conditions
WO2008039855A2 (en) 2006-09-26 2008-04-03 Baylor Research Institute Nutrient sensor
EP1929995A1 (en) 2006-12-04 2008-06-11 INSERM (Institut National de la Santé et de la Recherche Médicale) Anaplerotic therapy of Huntington disease and other polyglutamine diseases
KR100829729B1 (ko) * 2007-01-29 2008-05-15 한불화장품주식회사 병이소초 추출물을 주요 활성성분으로 함유하는 피부외용제 조성물
CN101878028A (zh) 2007-11-02 2010-11-03 普罗米蒂克生物科学公司 作为肾保护剂的中链长度脂肪酸和甘油酯
CN101879156B (zh) 2009-05-07 2013-01-30 上海医药工业研究院 一种药物组合物及其应用
US20110301238A1 (en) 2010-06-02 2011-12-08 Borges Karin Seizure related disorders and therapeutic methods thereof
CN103079555A (zh) 2010-06-14 2013-05-01 贝勒研究院 用于成人葡萄糖多聚体病（apbd）治疗的三庚酸甘油酯膳食
WO2013031729A1 (ja) 2011-08-26 2013-03-07 国立大学法人大阪大学 糖尿病性心血管合併症の予防・治療剤
CN102526643B (zh) * 2012-03-22 2013-09-11 常熟市虞山绿茶有限公司 一种治疗口腔溃疡的中草药含片
ES2728727T3 (es) 2012-12-13 2019-10-28 Baylor Res Institute At Dallas Triheptanoína para el tratamiento de la deficiencia del transportador de glucosa 1
US10751282B2 (en) * 2013-08-02 2020-08-25 Schweitzer-Mauduit International, Inc. Edible product comprising reconstituted plant material
US9833430B2 (en) * 2013-11-14 2017-12-05 The University Of Queensland Neurodegenerative disorders and methods of treatment and diagnosis thereof
WO2015110977A1 (en) 2014-01-22 2015-07-30 Rolexi Marketing (Pty) Ltd Fatty acid composition and medicinal use thereof
CN104286296A (zh) * 2014-09-25 2015-01-21 王美华 一种凉茶
JP6406978B2 (ja) 2014-11-04 2018-10-17 株式会社シー・アクト 脂肪酸混合物
CN105381182A (zh) 2015-11-20 2016-03-09 冯天寿 一种治疗慢性荨麻疹的中药及其应用
CA3004996A1 (en) 2015-12-04 2017-06-08 Nestec S.A. Method for improving cognition

Patent Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1309642A (zh) * 1998-05-11 2001-08-22 德雷斯顿药品工厂有限公司 具有止喘、抗变态反应、抗炎、免疫调节和神经保护作用的新的1,2,5－三取代1,2－二氢吲唑－3－酮类化合物、其制备方法以及作为药物的应用
CN1764446A (zh) * 2003-03-13 2006-04-26 康福玛医药公司 含有长链和中链甘油三酯的药物制剂
JP2005089375A (ja) * 2003-09-18 2005-04-07 Noevir Co Ltd 細胞賦活剤、美白剤、及び抗酸化剤
CN101137369A (zh) * 2005-02-09 2008-03-05 马库赛特公司 用于眼治疗的制剂
DE102008046227A1 (de) * 2008-06-10 2009-12-17 Ludwig-Maximilians-Universität München Hochdurchsatzmethode zur Analyse der Fettsäurezusammensetzung in Plasmaphosphoglyceriden
CN102215839A (zh) * 2008-11-18 2011-10-12 贝朗医疗有限公司 用于人工喂养重病的重症特护患者的脂肪乳剂
CN102781438A (zh) * 2009-12-30 2012-11-14 贝勒研究院 用于阿尔茨海默病和脑衰老的补给疗法
CN102821602A (zh) * 2010-01-08 2012-12-12 凯特贝希制药公司 脂肪酸富马酸酯衍生物及其用途
CN102883733A (zh) * 2010-02-10 2013-01-16 奥力榨油化株式会社 Age生成抑制剂
CN103096876A (zh) * 2010-07-15 2013-05-08 海布里詹尼克斯股份公司 维生素d的14-差向异构-类似物的制剂
CN103641713A (zh) * 2013-11-15 2014-03-19 浙江大学 甘油单酯衍生物的制备方法及应用
CN105267501A (zh) * 2015-11-04 2016-01-27 夏茂森 一种治疗毒蛇咬伤的中药组合物

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
尖峰岭药用蕨类植物资源调查与开发利用;陈能;钟琼芯;;热带生物学报(第04期);381-387+391 *

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