CN110141627A - A kind of skin wound care composition, care agent and preparation method - Google Patents

A kind of skin wound care composition, care agent and preparation method Download PDF

Info

Publication number
CN110141627A
CN110141627A CN201910408557.1A CN201910408557A CN110141627A CN 110141627 A CN110141627 A CN 110141627A CN 201910408557 A CN201910408557 A CN 201910408557A CN 110141627 A CN110141627 A CN 110141627A
Authority
CN
China
Prior art keywords
parts
wound care
skin wound
care composition
skin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201910408557.1A
Other languages
Chinese (zh)
Inventor
陈明毅
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zhongnanyuan (shenzhen) Pharmaceutical Research Co Ltd
Original Assignee
Zhongnanyuan (shenzhen) Pharmaceutical Research Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zhongnanyuan (shenzhen) Pharmaceutical Research Co Ltd filed Critical Zhongnanyuan (shenzhen) Pharmaceutical Research Co Ltd
Priority to CN201910408557.1A priority Critical patent/CN110141627A/en
Publication of CN110141627A publication Critical patent/CN110141627A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/64Insects, e.g. bees, wasps or fleas
    • A61K35/644Beeswax; Propolis; Royal jelly; Honey
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534Mentha (mint)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/886Aloeaceae (Aloe family), e.g. aloe vera
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02Local antiseptics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/31Extraction of the material involving untreated material, e.g. fruit juice or sap obtained from fresh plants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Botany (AREA)
  • Insects & Arthropods (AREA)
  • Dermatology (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a kind of skin wound care composition, care agent and preparation methods.Skin wound care composition includes the raw material of following weight parts: 2 parts~20 parts of ethyl alcohol, 1 part~10 parts of Aloe Vera Gel, 0.5 part~5 parts of propolis and 2 parts~20 parts of peppermint oil;Skin wound care agent includes above-mentioned skin wound care composition.Compared with prior art, the beneficial effects of the present invention are: ethyl alcohol and propolis have the function of bactericidal antiphlogistic in skin wound care composition of the invention, assistant is with peppermint oil, play the role of heat dissipation to relieve the pain, it is allowed to again with Aloe Vera Gel, and then there is skin wound care composition of the invention and accelerate union of wounded skin speed, reduce the advantages of skin wound is by bacterium infection risk;Surface of a wound care composition formula of the invention simultaneously is simple, at low cost.

Description

A kind of skin wound care composition, care agent and preparation method
Technical field
The invention belongs to sanitary care article technical fields, and in particular to a kind of skin wound care composition, care agent And preparation method.
Background technique
The processing mode of skin wound is generally divided into two kinds, and one is directly allow surface of a wound exposure to heal spontaneously in air; Another kind is to reduce skin wound to a certain extent by simply wrapping up by the risk of bacterium infection, equally allow skin wound Normal healing.But the healing rate of two kinds of processing mode skin wounds is slower, increases skin wound by the probability of bacterium infection.
Summary of the invention
In consideration of it, for slower, the skin that solves union of wounded skin speed in the processing mode of existing skin wound The surface of a wound problem high by bacterium infection probability, the present invention provide a kind of skin wound care composition.
The present invention also provides a kind of skin wound care agent and this skin comprising above-mentioned skin wound care composition The preparation method of skin surface of a wound care agent.
In order to achieve the above object, the technical scheme of the present invention is realized as follows:
A kind of skin wound care composition, the raw material including following weight parts: 2 parts~20 parts of ethyl alcohol, 1 part of Aloe Vera Gel~ 10 parts, 0.5 part~5 parts of propolis and 2 parts~20 parts of peppermint oil.
Preferably, the weight proportion of each component is as follows: 3 parts~8 parts of ethyl alcohol, 1 part~6 parts of Aloe Vera Gel, propolis 0.5 part~1 Part and 2 parts~8 parts of peppermint oil.
A kind of skin wound care agent including above-mentioned skin wound care composition.
A kind of skin wound care composition, the raw material including following weight parts: 2 parts~20 parts of ethyl alcohol, 1 part of Aloe Vera Gel~ 10 parts, 0.5 part~5 parts of propolis, 2 parts~20 parts of peppermint oil, 5 parts~25 parts of glycerol and 0.2 part~3.5 parts of edible essence.
Preferably, including the raw material of following weight parts: 3 parts~8 parts of ethyl alcohol, 1 part~6 parts of Aloe Vera Gel, propolis 0.5 part~1 Part and 2 parts~8 parts of peppermint oil, 10 parts~20 parts of glycerol and 0.5 part~3 parts of edible essence.
A kind of skin wound care agent including above-mentioned skin wound care composition.
Preferably, the dosage form of skin wound care agent is solution or lotion.
For above two skin wound care agent, propose two kinds to matched preparation method, specifically:
A kind of preparation method of skin wound care agent, this method are achieved by the steps of:
Step 1, each component that skin wound care composition is weighed by following weight proportions: 2 parts of ethyl alcohol~20 parts, aloe 1 part~10 parts of glue, 0.5 part~5 parts of propolis, 2 parts~20 parts of peppermint oil;
Step 2 uniformly mixes the skin wound care composition with purified water according to 1~6:10 of volume ratio, obtains Initial skin surface of a wound care agent;
Step 3, the initial skin surface of a wound care agent is carried out at 10Mpa~30Mpa high pressure sterilization 10min~ 20min obtains skin wound care agent.
The preparation method of another skin wound care agent, this method are achieved by the steps of:
Step 1, each component that skin wound care composition is weighed by following weight proportions: 2 parts of ethyl alcohol~20 parts, aloe 1 part~10 parts of glue, 0.5 part~5 parts of propolis, 2 parts~20 parts of peppermint oil, 5 parts~25 parts of glycerol and edible essence 0.2 part~3.5 Part;
Step 2 uniformly mixes the skin wound care composition with purified water according to 1~6:10 of volume ratio, obtains Initial skin surface of a wound care agent;
Step 3, the initial skin surface of a wound care agent is carried out at 10Mpa~30Mpa high pressure sterilization 10min~ 20min obtains skin wound care agent.
Preferably, the Aloe Vera Gel is prepared via a method which to obtain:
Fresh aloe cleaning, peeling, broken, homogeneous are obtained aloe magma by step 1, and centrifugation removes in aloe magma Plant fiber obtains Aloe original juice;
Active carbon powder is added into Aloe original juice for step 2, after stirring decolorization, crosses organic ultrafiltration membrane of 3000Da, Take filtrate;Wherein the mass ratio of the quality of active carbon powder and Aloe original juice is 0.3~0.5:100;
Step 3, by filtrate at 40Mpa~50Mpa, 30 DEG C~40 DEG C, be concentrated 10min~20min after, obtain aloe Glue.
Compared with prior art, antibiotic-free in skin wound care composition of the invention, will not cause to hurt to human body Evil, and the immune system of human body will not be had an impact;Using ethyl alcohol and propolis as monarch drug in a prescription, have the function of bactericidal antiphlogistic, assistant with Peppermint oil is played the role of heat dissipation and relieved the pain, then is allowed to Aloe Vera Gel, and then have skin wound care composition of the invention Accelerate union of wounded skin speed, reduces the advantages of skin wound is by bacterium infection risk;Skin wound shield of the invention simultaneously It is simple to manage composite formula, it is at low cost.
Skin wound care agent of the invention is directly applied on skin wound, easy to use;Skin wound care agent exists Protective layer is formed on skin wound, plays the role of physical barriers, can completely cut off extraneous bacterium, reduces skin wound by bacterium sense The probability of dye;With good gas permeability;And union of wounded skin speed can be accelerated, solve the place of existing skin wound Union of wounded skin speed is slower in reason mode, the skin wound problem high by bacterium infection probability.
The preparation method of skin wound care agent of the invention is easy to operate, is convenient for industrialized production.
Specific embodiment
In order to make the objectives, technical solutions, and advantages of the present invention clearer, below in conjunction with specific embodiment, to this Invention is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, not For limiting the present invention.
Embodiment 1
A kind of skin wound care composition, including following parts by weight of component: ethyl alcohol 2g, Aloe Vera Gel 1g, propolis 0.5g, thin Lotus oil 2g.
Embodiment 2
A kind of skin wound care composition, including following parts by weight of component: ethyl alcohol 20g, Aloe Vera Gel 10g, propolis 5g, thin Lotus oil 20g.
Embodiment 3
A kind of skin wound care composition, including following parts by weight of component: ethyl alcohol 3g, Aloe Vera Gel 1g, propolis 0.5g, thin Lotus oil 2g.
Embodiment 4
A kind of skin wound care composition, including following parts by weight of component: ethyl alcohol 8g, Aloe Vera Gel 6g, propolis 1g, peppermint Oily 8g.
Embodiment 5
A kind of skin wound care composition, including following parts by weight of component: ethyl alcohol 2g, Aloe Vera Gel 1g, propolis 0.5g, thin Lotus oil 2g, glycerol 10g, edible essence 0.5g.
Embodiment 6
A kind of skin wound care composition, including following parts by weight of component: ethyl alcohol 20g, Aloe Vera Gel 10g, propolis 5g, thin Lotus oil 20g, glycerol 20g, edible essence 3g.
Embodiment 7
A kind of skin wound care composition, including following parts by weight of component: ethyl alcohol 10g, Aloe Vera Gel 5g, propolis 3g, thin Lotus oil 15g, glycerol 15g, edible essence 1.5g.
Embodiment 8
A kind of skin wound care composition, including following parts by weight of component: ethyl alcohol 10g, Aloe Vera Gel 5g, propolis 3g, thin Lotus oil 15g, glycerol 5g, edible essence 0.2g
Embodiment 9
A kind of skin wound care composition, including following parts by weight of component: ethyl alcohol 10g, Aloe Vera Gel 5g, propolis 3g, thin Lotus oil 15g, glycerol 25g, edible essence 3.5g
The parts by weight content of each component in 1 above-described embodiment of table
Annotation: "/" is represented without this component.
The skin wound care composition of embodiment 1- embodiment 4 is prepared via a method which to obtain;
Firstly, weighing each component according to required parts by weight: ethyl alcohol, Aloe Vera Gel, propolis, peppermint oil;Then, by ethyl alcohol, Aloe Vera Gel, propolis, peppermint oil uniformly mix, and obtain required skin wound care composition.
The skin wound care composition of embodiment 5- embodiment 9 is prepared via a method which to obtain;
Firstly, weighing each component according to required parts by weight: ethyl alcohol, Aloe Vera Gel, propolis, peppermint oil, glycerol and edible perfume Essence;Then, ethyl alcohol, Aloe Vera Gel, propolis, peppermint oil, glycerol and edible essence are uniformly mixed, obtains required skin wound shield Manage composition.
Wherein, the type of edible essence can be determined according to the smell of required skin wound composition, such as wish skin The smell of skin surface of a wound composition is lemon, then edible essence can be lemon extract.
Aloe Vera Gel used in above-described embodiment can also be prepared via a method which to obtain by being commercially available 's.
Embodiment 10
Aloe Vera Gel is prepared via a method which to obtain:
Fresh aloe cleaning, peeling, broken, homogeneous are obtained aloe magma by step 1, and centrifugation removes in aloe magma Plant fiber obtains Aloe original juice;
Active carbon powder is added into Aloe original juice for step 2, after stirring decolorization, crosses organic ultrafiltration membrane of 3000Da, Take filtrate;;Wherein the mass ratio of the quality of active carbon powder and Aloe original juice is 0.3:100;
Step 3, by filtrate at 40Mpa, 30 DEG C, be concentrated 10min after, obtain Aloe Vera Gel.
Embodiment 11
Aloe Vera Gel is prepared via a method which to obtain:
Fresh aloe cleaning, peeling, broken, homogeneous are obtained aloe magma by step 1, and centrifugation removes in aloe magma Plant fiber obtains Aloe original juice;
Active carbon powder is added into Aloe original juice for step 2, after stirring decolorization, crosses organic ultrafiltration membrane of 3000Da, Take filtrate;Wherein the mass ratio of the quality of active carbon powder and Aloe original juice is 0.5:100;
Step 3, by filtrate at 50Mpa, 40 DEG C, be concentrated 20min after, obtain Aloe Vera Gel.
Embodiment 12
Aloe Vera Gel is prepared via a method which to obtain:
Fresh aloe cleaning, peeling, broken, homogeneous are obtained aloe magma by step 1, and centrifugation removes in aloe magma Plant fiber obtains Aloe original juice;
Active carbon powder is added into Aloe original juice for step 2, after stirring decolorization, crosses organic ultrafiltration membrane of 3000Da, Take filtrate;Wherein the mass ratio of the quality of active carbon powder and Aloe original juice is 0.4:100;
Step 3, by filtrate at 45Mpa, 35 DEG C, be concentrated 15min after, obtain Aloe Vera Gel.
Embodiment 13
A kind of skin wound care agent, dosage form are solution, skin wound care composition and 100ml including embodiment 3 Purified water.
Above-mentioned skin wound care agent is made by the steps to obtain:
Step 1, each component that skin wound care composition is weighed by following weight proportions: ethyl alcohol 3g, Aloe Vera Gel 1g, bee Glue 0.5g, peppermint oil 2g;
Step 2 uniformly mixes skin wound care composition with purified water according to volume ratio 1:10, obtains initial skin Surface of a wound care agent;
Initial skin surface of a wound care agent is carried out high pressure sterilization 10min by step 3 at 10Mpa, obtains skin wound nursing Agent solution.
Embodiment 14
A kind of skin wound care agent, dosage form are solution, skin wound care composition and 100ml including embodiment 4 Purified water.
Above-mentioned skin wound care agent is made by the steps to obtain:
Step 1, each component that skin wound care composition is weighed by following weight proportions: ethyl alcohol 8g, Aloe Vera Gel 6g, bee Glue 1g, peppermint oil 8g;
Step 2 uniformly mixes skin wound care composition with purified water according to volume ratio 3:10, obtains initial skin Surface of a wound care agent;
Initial skin surface of a wound care agent is carried out high pressure sterilization 15min by step 3 at 20Mpa, obtains skin wound nursing Agent solution.
Embodiment 15
A kind of skin wound care agent, dosage form are lotion, and skin wound care composition and 50mL including embodiment 6 are pure Change water.
Above-mentioned skin wound care agent is made by the steps to obtain:
Step 1, each component that skin wound care composition is weighed by following weight proportions: ethyl alcohol 20g, Aloe Vera Gel 10g, Propolis 5g, peppermint oil 20g, glycerol 20g, edible essence 3g;
Step 2 uniformly mixes skin wound care composition with purified water according to volume ratio 7:10, obtains initial skin Surface of a wound care agent;
Initial skin surface of a wound care agent is carried out high pressure sterilization 20min by step 3 at 30Mpa, obtains skin wound nursing Agent lotion.
Embodiment 16
A kind of skin wound care agent, dosage form are solution, skin wound care composition and 100ml including embodiment 7 Water.
Above-mentioned skin wound care agent is made by the steps to obtain:
Step 1, each component that skin wound care composition is weighed by following weight proportions: ethyl alcohol 10g, Aloe Vera Gel 5g, Propolis 3g, peppermint oil 15g, glycerol 15g, edible essence 1.5g;
Step 2 uniformly mixes skin wound care composition with purified water according to volume ratio 1:10, obtains initial skin Surface of a wound care agent;
Initial skin surface of a wound care agent is carried out high pressure sterilization 15min by step 3 at 30Mpa, obtains skin wound nursing Agent solution.
In order to verify the effect of skin wound care agent of the invention, such as following research.
(1) biocidal property is tested
Test strain: fungi, Candida albicans, staphylococcus aureus, enteropathogenic E. Coli.
Method: being made bacteria suspension with physiological saline for each test strain, and it is outstanding to be diluted to the bacterium that turbidity is 2.0McF or more Liquid, then with 100 times of normal saline dilution, RPMII640 dilutes 10 times, (the skin wound in the embodiment of the present invention 13 of experimental group 1 Care agent), experimental group 2 (the skin wound care agent in the embodiment of the present invention 16) and control group (purified water) doubling dilution, 96 72h~96h is cultivated in well culture plate, it is slight to shake, photoelectric colorimetry is carried out at 490nm, as a result such as table 2.
The antibacterial result of 2 experimental group of table and control group
, it can be seen that the skin wound care agent of experimental group of the present invention 1 and experimental group 2 is to fungi, Candida albicans from table 2 Bacterium, staphylococcus aureus, enteropathogenic E. Coli all have stronger antibacterial action, i.e., skin wound nursing group of the invention Closing object and skin wound care agent has bacteriostasis.
(2) zoopery
30 sd male rats on the 49th are taken, every weighs 250g~270g, on the right side of every rat back vertebra, cropping, Under narcosis, scraping surface of a wound size with scalpel is 2cm*2cm, and sd male rat is divided into experiment by the edge of a knife of depth 0.1cm Group 1, experimental group 2 and control group, every group of 10 sd male rats, wherein spraying the skin wound of the embodiment of the present invention 13 to experimental group 1 Agent solution is nursed in face, every time when injection, it is desirable that apart from surface of a wound 8cm~15cm even spraying, 2~5 spray every time, 3 times a day;Xiang Shi The skin wound nursing agent solution for testing the 2 spray embodiment of the present invention 16 of group, every time when injection, it is desirable that equal apart from surface of a wound 8cm~15cm It is even spraying, 2~5 spray every time, 3 times a day;The sd male rat of control group pastes the wound of Yunnan Baiyao after cleaning on the surface of a wound It can paste.
Record experimental group 1, the sd male rat in experimental group 2 and control group on day 1, the 2nd day, the 3rd day, the 5th day and 7th day, the quantity of surface of a wound incrustation, as a result such as table 3.
3 results of animal of table
From table 3, it can be seen that compared to control group, by experimental group 1 of the present invention and experimental group 2, treated that the surface of a wound can Quickly incrustation, i.e., skin wound care agent of the invention can promote the incrustation of the surface of a wound.
In conclusion all the components are pure natural component in skin wound care composition of the invention, antibiotic-free, It will not cause harm to the human body, and the immune system of human body will not be had an impact;Ethyl alcohol and propolis have the work of bactericidal antiphlogistic With assistant is played the role of heat dissipation and relieved the pain with peppermint oil, then is allowed to Aloe Vera Gel, and then make skin wound nursing group of the invention Closing object has the advantages of accelerating union of wounded skin speed, reduction skin wound is by bacterium infection risk;Wound of the invention simultaneously Care composition formula in face is simple, at low cost.
In addition, skin wound care agent of the invention is directly smeared or is sprayed on skin wound, skin wound care agent Protective layer is formed on skin wound, plays the role of physical barriers, can completely cut off extraneous bacterium, reduces skin wound by bacterium The probability of infection;With good gas permeability;And union of wounded skin speed can be accelerated, solve existing skin wound Union of wounded skin speed is slower in processing mode, the skin wound problem high by bacterium infection probability.
The foregoing is only a preferred embodiment of the present invention, but scope of protection of the present invention is not limited thereto, In the technical scope disclosed by the present invention, any changes or substitutions that can be easily thought of by anyone skilled in the art, It should be covered by the protection scope of the present invention.Therefore, protection scope of the present invention should be with scope of protection of the claims Subject to.

Claims (10)

1. a kind of skin wound care composition, which is characterized in that the raw material including following weight parts: 2 parts of ethyl alcohol~20 parts, reed 1 part~10 parts of luxuriant growth glue, 0.5 part~5 parts of propolis and 2 parts~20 parts of peppermint oil.
2. skin wound care composition according to claim 1, which is characterized in that the raw material including following weight parts: 3 parts~8 parts of ethyl alcohol, 1 part~6 parts of Aloe Vera Gel, 0.5 part~1 part of propolis and 2 parts~8 parts of peppermint oil.
3. a kind of skin wound care agent including skin wound care composition as claimed in claim 1 or 2.
4. a kind of skin wound care composition, which is characterized in that the raw material including following weight parts: 2 parts of ethyl alcohol~20 parts, reed 0.2 part of 1 part~10 parts of luxuriant growth glue, 0.5 part~5 parts of propolis, 2 parts~20 parts of peppermint oil, 5 parts~25 parts of glycerol and edible essence~ 3.5 part.
5. skin wound care composition according to claim 4, which is characterized in that the raw material including following weight parts: 2 parts~8 parts of 3 parts~8 parts of ethyl alcohol, 1 part~6 parts of Aloe Vera Gel, 0.5 part~1 part of propolis and peppermint oil, 10 parts~20 parts of glycerol and food With 0.5 part~3 parts of essence.
6. a kind of skin wound care agent including skin wound care composition as described in claim 4 or 5.
7. the skin wound care agent as described in claim 3 or 6, which is characterized in that the dosage form of the skin wound care agent For solution or lotion.
8. a kind of preparation method of skin wound care agent as claimed in claim 3, which is characterized in that this method passes through as follows Step is realized:
Step 1, each component that skin wound care composition is weighed by following weight proportions: 2 parts~20 parts of ethyl alcohol, Aloe Vera Gel 1 Part~10 parts, 0.5 part~5 parts of propolis, 2 parts~20 parts of peppermint oil;
Step 2 uniformly mixes the skin wound care composition with purified water according to 1~6:10 of volume ratio, obtains initial Skin wound care agent;
The initial skin surface of a wound care agent is carried out high pressure sterilization 10min~20min by step 3 at 10Mpa~30Mpa, is obtained To skin wound care agent.
9. a kind of preparation method of skin wound care agent as claimed in claim 6, which is characterized in that this method passes through as follows Step is realized:
Step 1, each component that skin wound care composition is weighed by following weight proportions: 2 parts~20 parts of ethyl alcohol, Aloe Vera Gel 1 Part~10 parts, 0.5 part~5 parts of propolis, 2 parts~20 parts of peppermint oil, 5 parts~25 parts of glycerol and 0.2 part~3.5 parts of edible essence;
Step 2 uniformly mixes the skin wound care composition with purified water according to 1~6:10 of volume ratio, obtains initial Skin wound care agent;
The initial skin surface of a wound care agent is carried out high pressure sterilization 10min~20min by step 3 at 10Mpa~30Mpa, is obtained To skin wound care agent.
10. the preparation method of skin wound care agent as claimed in claim 8 or 9, which is characterized in that the Aloe Vera Gel is logical Cross what following method was prepared:
Fresh aloe cleaning, peeling, broken, homogeneous are obtained aloe magma, the plant in centrifugation removal aloe magma by step 1 Fiber obtains Aloe original juice;
Active carbon powder is added into Aloe original juice for step 2, after stirring decolorization, crosses organic ultrafiltration membrane of 3000Da, takes filter Liquid;Wherein the mass ratio of the quality of active carbon powder and Aloe original juice is 0.3~0.5:100;
Step 3, by filtrate at 40Mpa~50Mpa, 30 DEG C~40 DEG C, be concentrated 10min~20min after, obtain Aloe Vera Gel.
CN201910408557.1A 2019-05-16 2019-05-16 A kind of skin wound care composition, care agent and preparation method Pending CN110141627A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201910408557.1A CN110141627A (en) 2019-05-16 2019-05-16 A kind of skin wound care composition, care agent and preparation method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201910408557.1A CN110141627A (en) 2019-05-16 2019-05-16 A kind of skin wound care composition, care agent and preparation method

Publications (1)

Publication Number Publication Date
CN110141627A true CN110141627A (en) 2019-08-20

Family

ID=67595688

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201910408557.1A Pending CN110141627A (en) 2019-05-16 2019-05-16 A kind of skin wound care composition, care agent and preparation method

Country Status (1)

Country Link
CN (1) CN110141627A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112826882A (en) * 2021-01-18 2021-05-25 吉安丽姝科技有限公司 Production process of traditional Chinese medicine type band-aid with disinfection and bacteriostasis functions
CN114886960A (en) * 2022-05-20 2022-08-12 庄五法 Antibacterial and anti-inflammatory skin repair cream

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1370588A (en) * 2002-03-05 2002-09-25 王舒妍 Aloe gelatin
CN1977943A (en) * 2005-12-09 2007-06-13 方昌阁 Topical burn composition
CN102366426A (en) * 2011-10-26 2012-03-07 江苏江大源生态生物科技有限公司 Propolis tincture for external use and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1370588A (en) * 2002-03-05 2002-09-25 王舒妍 Aloe gelatin
CN1977943A (en) * 2005-12-09 2007-06-13 方昌阁 Topical burn composition
CN102366426A (en) * 2011-10-26 2012-03-07 江苏江大源生态生物科技有限公司 Propolis tincture for external use and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
邱薇等: "芦荟蜂胶膏治疗兔试验性烧伤的疗效观察", 《西南国防医药》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112826882A (en) * 2021-01-18 2021-05-25 吉安丽姝科技有限公司 Production process of traditional Chinese medicine type band-aid with disinfection and bacteriostasis functions
CN114886960A (en) * 2022-05-20 2022-08-12 庄五法 Antibacterial and anti-inflammatory skin repair cream

Similar Documents

Publication Publication Date Title
CN110075036A (en) Anti- oral helicobacter pylori medicated toothpaste
CN102293724A (en) Cosmetic composition containing Chinese herbal compounds
CN106259509A (en) A kind of natural plant disinfectant and preparation method thereof
CN110141627A (en) A kind of skin wound care composition, care agent and preparation method
CN104451927B (en) A kind of Chinese medicine expelling parasite additive and application thereof
CN115317417A (en) Composition containing guaiacum extract for repairing acne sensitive muscle and skin care product thereof
CN111759885A (en) Sophora flavescens composition, sophora flavescens gel and preparation method thereof
CN106266189A (en) Compound recipe Radix Arnebiae (Radix Lithospermi) mosquito-expelling and antipruritic cream and preparation method thereof
CN105193686B (en) A kind of Feminine care solution and preparation method thereof
CN102784299A (en) External use ointment for promoting wound healing without scar pigment and preparation method of external use ointment
CN105250333B (en) A kind of pharmaceutical composition of antibacterial skin moistening and preparation method thereof
CN103599182A (en) Traditional Chinese medicine composition and preparation method thereof, and oral cavity cleaning and nursing product and preparation method thereof
CN106390182A (en) Sanitary napkin with antibacterial natural fiber surface layer and manufacturing method of sanitary napkin with antibacterial natural fiber surface layer
CN107050406A (en) Child's sterilizing liquid and preparation method thereof
CN114306526B (en) Compound broadleaf holly leaf traditional Chinese medicine extract and application thereof in preparing shower gel or hand sanitizer
CN110151915A (en) A kind of propolis oral nursing liquid and preparation method thereof
CN103239731B (en) Edible buccal patch for treating dental ulcer
CN109674875A (en) Oral ulcer nursing essence
CN111481567B (en) Compound ozone oil and preparation method and application thereof
CN110227103B (en) Composition for resisting oral pathogenic bacteria and preparation method and application thereof
CN104324277B (en) A kind of disinfection of Chinese drug liquid medicine
CN107788229A (en) A kind of purposes of plant-based bacteriostat
CN112386531A (en) Gleditsia sinensis oligosaccharide mask and preparation method thereof
CN102416068B (en) Cleaning and skin protection composition and preparation method
CN107875404B (en) Skin-moistening type medical ultrasonic coupling agent and preparation method and use method thereof

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
WD01 Invention patent application deemed withdrawn after publication
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20190820