CN109674875A - Oral ulcer nursing essence - Google Patents
Oral ulcer nursing essence Download PDFInfo
- Publication number
- CN109674875A CN109674875A CN201910157509.XA CN201910157509A CN109674875A CN 109674875 A CN109674875 A CN 109674875A CN 201910157509 A CN201910157509 A CN 201910157509A CN 109674875 A CN109674875 A CN 109674875A
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- Prior art keywords
- extract
- essence
- nurses
- canker sore
- oil
- Prior art date
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- 230000000474 nursing effect Effects 0.000 title abstract description 13
- 208000007117 Oral Ulcer Diseases 0.000 title abstract 4
- 208000002399 aphthous stomatitis Diseases 0.000 title abstract 4
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- OSWPMRLSEDHDFF-UHFFFAOYSA-N methyl salicylate Chemical compound COC(=O)C1=CC=CC=C1O OSWPMRLSEDHDFF-UHFFFAOYSA-N 0.000 claims abstract description 17
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Classifications
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
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- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
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- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention relates to the technical field of health care and nursing functional products, in particular to oral ulcer nursing essence, wherein the components of each raw material comprise an epigallocatechin gallate extract, an anti-allergy agent, a radix zanthoxyli extract, sodium monofluorophosphate, nicotinamide, propylene glycol, wintergreen oil, clove oil, tea tree oil, a sweetening agent, sodium dodecyl sulfate, glycerol, active zinc, a freshener, a thickening agent, a preservative, a buffering agent, allantoin and the balance of deionized water; the invention provides the oral ulcer care essence which is prepared from the raw materials without antibiotics, is a pure natural plant extract, has good biocompatibility, does not generate biological rejection reaction of oral tissues, and has no adverse side effect; has definite prevention and treatment effects on gingival bleeding, periodontal disease and sensitive toothache; when the quantitative sodium monofluorophosphate in the solution of the oral ulcer care essence is completely dissolved in water, calcium ions in the hydroxyapatite of the teeth are dissolved in a fluorion state and have the function of moth prevention.
Description
Technical field
The present invention relates to caring functional product technical fields, and in particular to canker sore nurses Essence.
Background technique
The health status in oral cavity be human health development portrayal, modern diet only demand it is ready-made ask speed, unbalanced nutrition.Add
Upper operating pressure is big, and the time of having a rest is chaotic.Canker sore is easy to happen.Past, traditional treatment ulcer method only use fungicide,
Based on antibiotic.Specific aim is not strong, and receptor does not dock.Not only therapeutic effect is bad, even more increases pain.And abuse antibiosis
Element causes disruption of ecological balance, brings on a disaster for environment.
Treatment Ulcer medicine is most of by biocide agent allusion quotation (I) and multistage quaternary ammonium salt cationic fungicide at present, such as: western pyrrole chlorine
Ammonium (CPC), chlorhexidine, (PHMB) etc..These substances are to kill based on the bacterium of surface, but effect is poor, not can solve ulcers pain
It is bitter.There are also steroids patch is used, effect is equally not all right.These are unable to counterpart chamber mucous membrane at all and generate healing effect, can only increase
Add treatment time, increases patient suffering.
In the treatment Ulcer medicine be made of fungicide or hormone, although skin surface flora can be killed, mouth is had ignored
Countless bacterium colonies existing for the chamber moment.What these beneficial and harmful floras did not under normal circumstances injure us in body, greatly
Part flora is to aid in body growth.When certain bacterial flora alternation, our body own systems, which can be generated, can swash reaction, meeting
Change hormonal variation.Such as generate certain and do not accommodate a degree of physical reaction, to increase the treatment of mouth disease
Time.
Summary of the invention
Therefore, the present invention provides canker sore to nurse Essence, does not have antibiotic group in raw material at not injuring mouth
Chamber, without adverse side effect；And to bleeding gums, periodontosis, sensitivity, which is had a toothache, definite prophylactic-therapeutic effect.
In order to achieve the above object, the present invention is achieved by the following technical programs:
Canker sore nurses Essence, wherein each material composition is by weight: Myrrha extract 2~4%, anti-anaphylaxis agent
0.6~0.9%, Radix Zanthoxyli extract 0.5~0.9%, sodium monofluorophosphate 0.5~0.6%, niacinamide 0.1~0.3%, the third two
Alcohol 3~4%, wintergreen 0.01~0.03%, caryophyllus oil 0.005~0.01%, tea oil 0.03~0.05%, sweetener
0.085~0.1%, lauryl sodium sulfate 0.6~0.8%, glycerol 12~15%, active zinc 0.05~0.07%, freshener
0.1~0.3%, thickener 1.5~1.8%, preservative 0.38~0.42%, buffer 0.1~0.2%, allantoin 0.3~
0.6%, surplus is deionized water.
Further, raw material are to extract containing Myrrha extract 2%, scutelloside 0.1%, tea polyphenols 0.3%, Radix zanthoxyli
Object 0.5%, niacinamide 0.1%, propylene glycol 3%, wintergreen 0.01%, caryophyllus oil 0.005%, tea oil 0.03%, sweetener
0.085%, glycerol 12%, lauryl sodium sulfate 0.6%, active zinc 0.05% mixing liquid state species.
Further, the active zinc is zinc gluconate, and the buffer is by sodium bicarbonate and Pfansteihl sodium two
Kind composition.
Further, the anti-anaphylaxis agent be 0.2~0.3% willow leaf calyx canthus extract, 0.1~0.2% scutelloside,
The mixture of 0.3~0.4% tea polyphenols composition.
Further, the sweetener is Sucralose, and the freshener is menthol, and the buffer is lemon
Lemon acid sodium, the thickener are corn carbohydrate gum.
Further, the mixture that the preservative forms for 0.15% potassium cinnamate and 0.23% triclosan.
Further, the preparation method of the canker sore nursing Essence includes the following steps:
1) it prepares mixing A: being heated to 60 DEG C using 30~35% deionized waters, will, 0.6~0.8% dodecyl sulphur
The dissolution of sour sodium, be put into triclosan, freshener, natural tea tree oil, natural winter-green oil, natural caryophyllus oil and propylene glycol sufficiently do mix it is mixed
Dissolution is closed, mixing A is made；
2) it prepares mixed material B: being dissolved allantoin with remaining deionized water, then constantly do to mix being respectively put into myrrh extraction
Object, scutelloside (be added 2 times of saturated solution of sodium bicarbonate), tea polyphenols, Radix Zanthoxyli extract, niacinamide, sweetener, active zinc,
Mixed material B is made in potassium cinnamate, buffer and thickener (first being dispersed with glycerol)；
3) it is blended: by mixed material B obtained in mixing A made from step 1 and step 2, being sufficiently mixed and remaining increasing is added
Thick dose (first being dispersed with glycerol), be de-gassed to get dilute cream shape transparency liquid after moderate-speed mixer is uniform in a mixing bowl.
Further, the Myrrha extract, scutelloside, tea polyphenols and Radix Zanthoxyli extract must completely soluble shapes
At transparence solion state.
Further, scutelloside that the content is 0.2% Myrrha extract, content are 0.1%, content are
0.3% tea polyphenols, composition gold combination.
Further, scutelloside palpus content is 80~85%, and by extracting in natural radix scutellariae, the tea polyphenols
Content 85~95%, by extracting in natural leaf tea, the Myrrha extract must be Somalia's extract.
The present invention have it is below the utility model has the advantages that
1, quantitative single fluorine phosphorus sodium in solution of the present invention is completely dissolved in water, dissolves tooth hydroxyl phosphorus with fluorine ion state
Calcium ion in lime stone and serve mothproof.
2, it is combined by the gold of scutelloside, tea polyphenols and myrrh, there is high biological negative electricity lotus adsorption capacity.It is planted with atom
The heavy ulcer affected part blocking external substance that is attached to of object state enters, and plays anti-inflammatory analgetic, repairs the effect of holding back.Sensitive toothache can be prevented again.It is yellow
A kind of reed mentioned in ancient books glycosides, tea polyphenols, myrrh gold combine substance, have sterilizing inflammation-diminishing function, act the function of eliminating bad breath in the oral cavity.Its biology is negative
Charge is combined rapidly with the ulcer surface mucous membrane under isoelectric point, plays quickly alleviating pain, rapid repairing ulcer effect.
3, the present invention uses scutelloside, tea polyphenols, and the combination of myrrh gold is avoided using fungicide and steroids.In addition, yellow
A kind of reed mentioned in ancient books glycosides, tea polyphenols, the combination of myrrh gold is pure natural plant extract matter, has good biocompatibility, will not oral cavity group
The biological rejection reaction of generation is knitted, and can be absorbed by the body and utilize object to be beneficial.
4, canker sore nursing Essence provided by the invention can handle a variety of oral problems simultaneously, and effect is obvious and holds
The continuous time is long.The method that other treatment mouth diseases are substituted in the canker sore nursing comprehensive degree of essence, reduces oral cavity
Maintenance cost.
Specific embodiment
In order to make the object, technical scheme and advantages of the embodiment of the invention clearer, below in conjunction with the embodiment of the present invention,
Technical scheme in the embodiment of the invention is clearly and completely described, it is clear that described embodiment is the present invention one
Divide embodiment, instead of all the embodiments.Based on the embodiments of the present invention, those of ordinary skill in the art are not making
Every other embodiment obtained, shall fall within the protection scope of the present invention under the premise of creative work.
Embodiment 1:
Canker sore nurses Essence, wherein each material composition is by weight: Myrrha extract 3%, anti-anaphylaxis agent
0.6%, Radix Zanthoxyli extract 0.8%, sodium monofluorophosphate 0.5%, niacinamide 0.1%, propylene glycol 4%, wintergreen 0.02%, fourth
Sesame oil 0.005%, tea oil 0.03%, sweetener 0.085%, lauryl sodium sulfate 0.7%, glycerol 13%, active zinc
0.05%, freshener 0.3%, thickener 1.5%, preservative 0.38%, buffer 0.2%, allantoin 0.5%, surplus are to go
Ionized water.
Active zinc therein is zinc gluconate, and buffer is made of sodium bicarbonate and two kinds of Pfansteihl sodium.
Anti-anaphylaxis agent therein be 0.2% willow leaf calyx canthus extract, 0.1% scutelloside, 0.3% tea polyphenols composition
Mixture.
Sweetener therein is Sucralose, and freshener is menthol, and buffer is sodium citrate, and thickener is primverose
Glue.
Preservative therein is the mixture that 0.15% potassium cinnamate and 0.23% triclosan form.
The preparation method of canker sore nursing Essence therein includes the following steps:
1) it prepares mixing A: being heated to 60 DEG C using 33% deionized water, will, 0.7% lauryl sodium sulfate dissolution,
It is put into triclosan, freshener, natural tea tree oil, natural winter-green oil, natural caryophyllus oil and propylene glycol and sufficiently does and mix mixed dissolution, make
Obtain mixing A；
2) it prepares mixed material B: being dissolved allantoin with remaining deionized water, then constantly do to mix being respectively put into myrrh extraction
Object, scutelloside (be added 2 times of saturated solution of sodium bicarbonate), tea polyphenols, Radix Zanthoxyli extract, niacinamide, sweetener, active zinc,
Mixed material B is made in potassium cinnamate, buffer and thickener (first being dispersed with glycerol)；
3) it is blended: by mixed material B obtained in mixing A made from step 1 and step 2, being sufficiently mixed and remaining increasing is added
Thick dose (first being dispersed with glycerol), be de-gassed to get dilute cream shape transparency liquid after moderate-speed mixer is uniform in a mixing bowl.
Myrrha extract, scutelloside, tea polyphenols and Radix Zanthoxyli extract therein must completely soluble formation transparences
Solion state.
Scutelloside palpus content therein is 82%, and by extracting in natural radix scutellariae, polyphenol content 88%, by natural leaf tea
Middle extraction, Myrrha extract must be Somalia's extract.
Embodiment 2:
Canker sore nurses Essence, wherein each material composition is by weight: Myrrha extract 2%, anti-anaphylaxis agent
0.6%, Radix Zanthoxyli extract 0.5%, sodium monofluorophosphate 0.5%, niacinamide 0.1%, propylene glycol 3%, wintergreen 0.01%, fourth
Sesame oil 0.005%, tea oil 0.03%, sweetener 0.085%, lauryl sodium sulfate 0.6%, glycerol 12%, active zinc
0.05%, freshener 0.1%, thickener 1.5%, preservative 0.38%, buffer 0.1%, allantoin 0.3%, surplus are to go
Ionized water.
Active zinc therein is zinc gluconate, and buffer is made of sodium bicarbonate and two kinds of Pfansteihl sodium.
Anti-anaphylaxis agent therein be 0.2% willow leaf calyx canthus extract, 0.1% scutelloside, 0.3% tea polyphenols composition
Mixture.
Sweetener therein is Sucralose, and freshener is menthol, and buffer is sodium citrate, and thickener is primverose
Glue.
Preservative therein is the mixture that 0.15% potassium cinnamate and 0.23% triclosan form.
The preparation method of canker sore nursing Essence therein includes the following steps:
1) it prepares mixing A: being heated to 60 DEG C using 30% deionized water, will, 0.6% lauryl sodium sulfate dissolution,
It is put into triclosan, freshener, natural tea tree oil, natural winter-green oil, natural caryophyllus oil and propylene glycol and sufficiently does and mix mixed dissolution, make
Obtain mixing A；
2) it prepares mixed material B: being dissolved allantoin with remaining deionized water, then constantly do to mix being respectively put into myrrh extraction
Object, scutelloside (be added 2 times of saturated solution of sodium bicarbonate), tea polyphenols, Radix Zanthoxyli extract, niacinamide, sweetener, active zinc,
Mixed material B is made in potassium cinnamate, buffer and thickener (first being dispersed with glycerol)；
3) it is blended: by mixed material B obtained in mixing A made from step 1 and step 2, being sufficiently mixed and remaining increasing is added
Thick dose (first being dispersed with glycerol), be de-gassed to get dilute cream shape transparency liquid after moderate-speed mixer is uniform in a mixing bowl.
Myrrha extract, scutelloside, tea polyphenols and Radix Zanthoxyli extract therein must completely soluble formation transparences
Solion state.
Scutelloside palpus content therein is 80%, and by extracting in natural radix scutellariae, polyphenol content 90%, by natural leaf tea
Middle extraction, Myrrha extract must be Somalia's extract.
Embodiment 3:
Canker sore nurses Essence, wherein each material composition is by weight: Myrrha extract 2%, anti-anaphylaxis agent
0.8%, Radix Zanthoxyli extract 0.5%, sodium monofluorophosphate 0.6%, niacinamide 0.1%, propylene glycol 4%, wintergreen 0.01%, fourth
Sesame oil 0.01%, tea oil 0.05%, sweetener 0.09%, lauryl sodium sulfate 0.6%, glycerol 12%, active zinc
0.05%, freshener 0.1%, thickener 1.8%, preservative 0.42%, buffer 0.1%, allantoin 0.5%, surplus are to go
Ionized water.
Active zinc therein is zinc gluconate, and buffer is made of sodium bicarbonate and two kinds of Pfansteihl sodium.
Anti-anaphylaxis agent therein be 0.2% willow leaf calyx canthus extract, 0.2% scutelloside, 0.4% tea polyphenols composition
Mixture.
Sweetener therein is Sucralose, and freshener is menthol, and buffer is sodium citrate, and thickener is primverose
Glue.
Preservative therein is the mixture that 0.15% potassium cinnamate and 0.23% triclosan form.
The preparation method of canker sore nursing Essence therein includes the following steps:
1) it prepares mixing A: being heated to 60 DEG C using 32% deionized water, will, 0.7% lauryl sodium sulfate dissolution,
It is put into triclosan, freshener, natural tea tree oil, natural winter-green oil, natural caryophyllus oil and propylene glycol and sufficiently does and mix mixed dissolution, make
Obtain mixing A；
2) it prepares mixed material B: being dissolved allantoin with remaining deionized water, then constantly do to mix being respectively put into myrrh extraction
Object, scutelloside (be added 2 times of saturated solution of sodium bicarbonate), tea polyphenols, Radix Zanthoxyli extract, niacinamide, sweetener, active zinc,
Mixed material B is made in potassium cinnamate, buffer and thickener (first being dispersed with glycerol)；
3) it is blended: by mixed material B obtained in mixing A made from step 1 and step 2, being sufficiently mixed and remaining increasing is added
Thick dose (first being dispersed with glycerol), be de-gassed to get dilute cream shape transparency liquid after moderate-speed mixer is uniform in a mixing bowl.
Myrrha extract, scutelloside, tea polyphenols and Radix Zanthoxyli extract therein must completely soluble formation transparences
Solion state.
Scutelloside palpus content therein is 84%, and by extracting in natural radix scutellariae, polyphenol content 92%, by natural leaf tea
Middle extraction, Myrrha extract must be Somalia's extract.
Embodiment 4:
Canker sore nurses Essence, wherein each material composition is by weight: Myrrha extract 4%, anti-anaphylaxis agent
0.9%, Radix Zanthoxyli extract 0.9%, sodium monofluorophosphate 0.6%, niacinamide 0.3%, propylene glycol 4%, wintergreen 0.03%, fourth
Sesame oil 0.01%, tea oil 0.05%, sweetener 0.1%, lauryl sodium sulfate 0.8%, glycerol 15%, active zinc
0.07%, freshener 0.3%, thickener 1.8%, preservative 0.42%, buffer 0.2%, allantoin 0.6%, surplus are to go
Ionized water.
Active zinc therein is zinc gluconate, and buffer is made of sodium bicarbonate and two kinds of Pfansteihl sodium.
Anti-anaphylaxis agent therein be 0.3% willow leaf calyx canthus extract, 0.2% scutelloside, 0.4% tea polyphenols composition
Mixture.
Sweetener therein is Sucralose, and freshener is menthol, and buffer is sodium citrate, and thickener is primverose
Glue.
Preservative therein is the mixture that 0.15% potassium cinnamate and 0.23% triclosan form.
The preparation method of canker sore nursing Essence therein includes the following steps:
1) it prepares mixing A: being heated to 60 DEG C using 35% deionized water, will, 0.8% lauryl sodium sulfate dissolution,
It is put into triclosan, freshener, natural tea tree oil, natural winter-green oil, natural caryophyllus oil and propylene glycol and sufficiently does and mix mixed dissolution, make
Obtain mixing A；
2) it prepares mixed material B: being dissolved allantoin with remaining deionized water, then constantly do to mix being respectively put into myrrh extraction
Object, scutelloside (be added 2 times of saturated solution of sodium bicarbonate), tea polyphenols, Radix Zanthoxyli extract, niacinamide, sweetener, active zinc,
Mixed material B is made in potassium cinnamate, buffer and thickener (first being dispersed with glycerol)；
3) it is blended: by mixed material B obtained in mixing A made from step 1 and step 2, being sufficiently mixed and remaining increasing is added
Thick dose (first being dispersed with glycerol), be de-gassed to get dilute cream shape transparency liquid after moderate-speed mixer is uniform in a mixing bowl.
Myrrha extract, scutelloside, tea polyphenols and Radix Zanthoxyli extract therein must completely soluble formation transparences
Solion state.
Scutelloside palpus content therein is 85%, and by extracting in natural radix scutellariae, polyphenol content 95%, by natural leaf tea
Middle extraction, Myrrha extract must be Somalia's extract.
Embodiment 5:
Canker sore nurses Essence, wherein each material composition is by weight: Myrrha extract 3%, anti-anaphylaxis agent
0.6%, Radix Zanthoxyli extract 0.5%, sodium monofluorophosphate 0.5%, niacinamide 0.1%, propylene glycol 3%, wintergreen 0.01%, fourth
Sesame oil 0.007%, tea oil 0.04%, sweetener 0.088%, lauryl sodium sulfate 0.6%, glycerol 12%, active zinc
0.07%, freshener 0.1%, thickener 1.5%, preservative 0.42%, buffer 0.2%, allantoin 0.3%, surplus are to go
Ionized water.
Active zinc therein is zinc gluconate, and buffer is made of sodium bicarbonate and two kinds of Pfansteihl sodium.
Anti-anaphylaxis agent therein be 0.2% willow leaf calyx canthus extract, 0.1% scutelloside, 0.3% tea polyphenols composition
Mixture.
Sweetener therein is Sucralose, and freshener is menthol, and buffer is sodium citrate, and thickener is primverose
Glue.
Preservative therein is the mixture that 0.15% potassium cinnamate and 0.23% triclosan form.
The preparation method of canker sore nursing Essence therein includes the following steps:
1) it prepares mixing A: being heated to 60 DEG C using 33% deionized water, will, 0.6% lauryl sodium sulfate dissolution,
It is put into triclosan, freshener, natural tea tree oil, natural winter-green oil, natural caryophyllus oil and propylene glycol and sufficiently does and mix mixed dissolution, make
Obtain mixing A；
2) it prepares mixed material B: being dissolved allantoin with remaining deionized water, then constantly do to mix being respectively put into myrrh extraction
Object, scutelloside (be added 2 times of saturated solution of sodium bicarbonate), tea polyphenols, Radix Zanthoxyli extract, niacinamide, sweetener, active zinc,
Mixed material B is made in potassium cinnamate, buffer and thickener (first being dispersed with glycerol)；
3) it is blended: by mixed material B obtained in mixing A made from step 1 and step 2, being sufficiently mixed and remaining increasing is added
Thick dose (first being dispersed with glycerol), be de-gassed to get dilute cream shape transparency liquid after moderate-speed mixer is uniform in a mixing bowl.
Myrrha extract, scutelloside, tea polyphenols and Radix Zanthoxyli extract therein must completely soluble formation transparences
Solion state.
Scutelloside palpus content therein is 85%, and by extracting in natural radix scutellariae, polyphenol content 90%, by natural leaf tea
Middle extraction, Myrrha extract must be Somalia's extract.
Medicinal experiment:
In October, 2017 and in October, 2018 respectively to 80, the canker sore patient outcome of 40 different selections every time
Test tracking.4 groups of patients are selected to nurse Essence to commercially available chlorhexidine lozenge, allusion quotation lozenge and containing steroids emplastrum canker sore
As a comparison, it carries out testing for 7 days.Selecting the treatment of chlorhexidine lozenge is A group, and selecting canker sore nursing Essence treatment is B group,
Selecting allusion quotation lozenge is C group.Selecting containing steroids emplastrum is D group.It is put on the skin respectively in canker sore affected part, wherein testing every group
10 people.In every 10 people, 6 to 12 years old 3 people.12 to 35 years old 4 people.36 to 75 years old 3 people.Male 7 people, 3 people of female, and every group wherein 6 people it is normal
Suffer from ulcer, 2 people are small to be had, and 2 people do not have.Women therein respectively accounts for 1 people in all ages and classes stage respectively.
It uses 1 minute initial trial: patient being allowed to illustrate that application method uses by each respectively.As a result following display:
1:1 minutes experimental test results of table
| Group (people) | There is pain | Without pain |
| A group | 7 | 3 |
| B group | 0 | 10 |
| C group | 8 | 2 |
| D group | 1 | 9 |
It is tested by above-mentioned initial experiment, illustrates that nurse Essence containing canker sore provided by the invention has in the short time
There is analgesic sealing process.Therefore further, Essence is nursed to canker sore prepared by the present invention, carries out the effect that whole day is taken
Fruit test.
It was tested using 1 day to 2 days: patient being allowed to illustrate that application method uses by each respectively.As a result as follows:
Table 2:1 to 2 days experimental test result
| Group (people) | There is pain | Without pain |
| A group | 9 | 1 |
| B group | 1 | 9 |
| C group | 9 | 1 |
| D group | 8 | 2 |
It was tested using 3 days: patient being allowed to illustrate that application method uses by each respectively.As a result as follows:
3:3 days experimental test results of table
| Group (people) | There is pain | Without pain |
| A group | 7 | 3 |
| B group | 1 | 9 |
| C group | 7 | 3 |
| D group | 8 | 2 |
It was tested using 4 days: patient being allowed to illustrate that application method uses by each respectively.As a result as follows:
4:4 days experimental test results of table
| Group (people) | There is pain | Without pain |
| A group | 7 | 3 |
| B group | 1 | 9 |
| C group | 6 | 4 |
| D group | 6 | 4 |
It was tested using 5 days: patient being allowed to illustrate that application method uses by each respectively.As a result as follows:
5:5 days experimental test results of table
| Group (people) | There is pain | Without pain |
| A group | 8 | 2 |
| B group | 1 | 9 |
| C group | 8 | 2 |
| D group | 8 | 2 |
It was tested using 6 days: patient being allowed to illustrate that application method uses by each respectively.As a result as follows:
6:6 days experimental test results of table
| Group (people) | There is pain | Without pain |
| A group | 8 | 2 |
| B group | 0 | 10 |
| C group | 9 | 1 |
| D group | 9 | 1 |
It is shown by the test result of above-mentioned short time and the medicinal test of prolonged multiple groups, oral cavity provided by the invention is burst
Ulcer nursing Essence truly has obvious curative effects to canker sore.
It should be noted that, in this document, relational terms such as first and second and the like are used merely to a reality
Body or operation are distinguished with another entity or operation, are deposited without necessarily requiring or implying between these entities or operation
In any actual relationship or order or sequence.Moreover, the terms "include", "comprise" or its any other variant are intended to
Non-exclusive inclusion, so that the process, method, article or equipment including a series of elements is not only wanted including those
Element, but also including other elements that are not explicitly listed, or further include for this process, method, article or equipment
Intrinsic element.In the absence of more restrictions, the element limited by sentence "including a ...", it is not excluded that
There is also other identical elements in process, method, article or equipment including element.
The above embodiments are merely illustrative of the technical solutions of the present invention, rather than its limitations；Although with reference to the foregoing embodiments
Invention is explained in detail, those skilled in the art should understand that: it still can be to aforementioned each implementation
Technical solution documented by example is modified or equivalent replacement of some of the technical features；And these modification or
Replacement, the spirit and scope for technical solution of various embodiments of the present invention that it does not separate the essence of the corresponding technical solution.
Claims (10)
1. canker sore nurses Essence, which is characterized in that wherein each material composition is by weight: Myrrha extract 2~
4%, anti-anaphylaxis agent 0.6~0.9%, Radix Zanthoxyli extract 0.5~0.9%, sodium monofluorophosphate 0.5~0.6%, niacinamide 0.1~
0.3%, propylene glycol 3~4%, wintergreen 0.01~0.03%, caryophyllus oil 0.005~0.01%, tea oil 0.03~0.05%,
Sweetener 0.085~0.1%, lauryl sodium sulfate 0.6~0.8%, glycerol 12~15%, active zinc 0.05~0.07%,
Freshener 0.1~0.3%, thickener 1.5~1.8%, preservative 0.38~0.42%, buffer 0.1~0.2%, allantoin
0.3~0.6%, surplus is deionized water.
2. canker sore according to claim 1 nurses Essence, it is characterised in that: raw material are to contain Myrrha extract
2%, scutelloside 0.1%, tea polyphenols 0.3%, Radix Zanthoxyli extract 0.5%, niacinamide 0.1%, propylene glycol 3%, wintergreen
0.01%, caryophyllus oil 0.005%, tea oil 0.03%, sweetener 0.085%, glycerol 12%, lauryl sodium sulfate 0.6%,
The mixing liquid state species of active zinc 0.05%.
3. canker sore according to claim 1 nurses Essence, it is characterised in that: the active zinc is gluconic acid
Zinc, the buffer are made of sodium bicarbonate and two kinds of Pfansteihl sodium.
4. canker sore according to claim 1 nurses Essence, it is characterised in that: the anti-anaphylaxis agent is 0.2~
0.3% willow leaf calyx canthus extract, 0.1~0.2% scutelloside, 0.3~0.4% tea polyphenols composition mixture.
5. canker sore according to claim 1 nurses Essence, it is characterised in that: the sweetener is trichlorine sugarcane
Sugar, the freshener are menthol, and the buffer is sodium citrate, and the thickener is corn carbohydrate gum.
6. canker sore according to claim 1 nurses Essence, it is characterised in that: the preservative is 0.15%
Potassium cinnamate and 0.23% triclosan composition mixture.
7. canker sore according to claim 1 nurses Essence, which is characterized in that preparation method includes the following steps:
1) it prepares mixing A: being heated to 60 DEG C using 30~35% deionized waters, will, 0.6~0.8% lauryl sodium sulfate
Dissolution, be put into triclosan, freshener, natural tea tree oil, natural winter-green oil, natural caryophyllus oil and propylene glycol sufficiently do mix mixing it is molten
Mixing A is made in solution；
2) it prepares mixed material B: allantoin being dissolved with remaining deionized water, then constantly does to mix being respectively put into Myrrha extract, Huang
A kind of reed mentioned in ancient books glycosides (2 times of saturated solution of sodium bicarbonate are added), tea polyphenols, Radix Zanthoxyli extract, niacinamide, sweetener, active zinc, cinnamic acid
Mixed material B is made in potassium, buffer and thickener (first being dispersed with glycerol)；
3) it is blended: by mixed material B obtained in mixing A made from step 1 and step 2, being sufficiently mixed and remaining thickener is added
(first being dispersed with glycerol) is de-gassed after moderate-speed mixer is uniform in a mixing bowl to get dilute cream shape transparency liquid.
8. canker sore according to claim 7 nurses Essence, it is characterised in that: the Myrrha extract, radix scutellariae
Glycosides, tea polyphenols and Radix Zanthoxyli extract must completely soluble formation transparence solion states.
9. canker sore according to claim 7 nurses Essence, it is characterised in that: the content is 0.2% not have
The tea polyphenols that scutelloside that medicament extract, content are 0.1%, content are 0.3%, composition gold combination.
10. canker sore according to claim 7 nurses Essence, it is characterised in that: the scutelloside must content be
80~85%, and by being extracted in natural radix scutellariae, the polyphenol content 85~95% is described by extracting in natural leaf tea
Myrrha extract must be Somalia's extract.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910157509.XA CN109674875A (en) | 2019-03-01 | 2019-03-01 | Oral ulcer nursing essence |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910157509.XA CN109674875A (en) | 2019-03-01 | 2019-03-01 | Oral ulcer nursing essence |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109674875A true CN109674875A (en) | 2019-04-26 |
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| CN201910157509.XA Pending CN109674875A (en) | 2019-03-01 | 2019-03-01 | Oral ulcer nursing essence |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110507813A (en) * | 2019-10-12 | 2019-11-29 | 德州学院 | Cure mainly the traditional Chinese medicine reagent and its preparation method of canker sore |
| WO2022026672A1 (en) * | 2020-07-31 | 2022-02-03 | Colgate-Palmolive Company | Process for producing an oral care composition |
| CN116172886A (en) * | 2022-06-29 | 2023-05-30 | 广州何济堂生物科技有限公司 | Mouthwash and preparation method thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108618980A (en) * | 2018-06-08 | 2018-10-09 | 叶绿芝生物科技（中山）有限公司 | A kind of multi-functional liquid tooth paste |
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2019
- 2019-03-01 CN CN201910157509.XA patent/CN109674875A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108618980A (en) * | 2018-06-08 | 2018-10-09 | 叶绿芝生物科技（中山）有限公司 | A kind of multi-functional liquid tooth paste |
Non-Patent Citations (1)
| Title |
|---|
| 林荣欣: "牙膏配方暨产品知识面面观", 《牙膏工业》 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110507813A (en) * | 2019-10-12 | 2019-11-29 | 德州学院 | Cure mainly the traditional Chinese medicine reagent and its preparation method of canker sore |
| WO2022026672A1 (en) * | 2020-07-31 | 2022-02-03 | Colgate-Palmolive Company | Process for producing an oral care composition |
| US11701314B2 (en) | 2020-07-31 | 2023-07-18 | Colgate-Palmolive Company | Processes and methods |
| CN116172886A (en) * | 2022-06-29 | 2023-05-30 | 广州何济堂生物科技有限公司 | Mouthwash and preparation method thereof |
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