CN110507813A - Cure mainly the traditional Chinese medicine reagent and its preparation method of canker sore - Google Patents
Cure mainly the traditional Chinese medicine reagent and its preparation method of canker sore Download PDFInfo
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Abstract
Cure mainly the traditional Chinese medicine reagent and its preparation method of canker sore, it is made of sterilizing collutory and oral care potus, sterilizing collutory is made of refine glycerol, peppermint oil, lauryl sodium sulfate, soyabean oligosaccharides, different qualityxylans, freshener WS-23, calcium carbonate, disodium hydrogen phosphate and pure water of natamycin, nisin, phenyllactic acid, sodium bicarbonate, biology；Oral care potus is made of Radix Astragali, Radix Angelicae Sinensis, ramulus cinnamomi, Radix Paeoniae Alba, dark plum, burnt short, bristly hair or beard, cortex cinnamomi, radix aucklandiae, Hericium erinaceus, seaweed, Prunella vulgaris, Radix Glycyrrhizae and deionized water.Present invention sterilizing collutory can effectively kill and inhibit the G such as porphyromonas gingivalis, bacterium actinomycetem comitans, Fusobacterium, the streptococcus mutans in oral cavity+、G‑Bacterium, and the plaque bio-film generated to flora has decomposition；Oral care potus is by Radix Astragali；Radix Angelicae Sinensis；Ramulus cinnamomi；Radix Paeoniae Alba；Dark plum；Burnt short, bristly hair or beard；Cortex cinnamomi；Radix aucklandiae；Hericium erinaceus and Radix Glycyrrhizae compatibility promote canker sore healing, mitigate pain, and long-time service can enhance immunity of organisms.
Description
Technical field
The present invention relates to a kind of oral care potus, and in particular to a kind of traditional Chinese medicine reagent and its preparation for curing mainly canker sore
Method.
Background technique
Canker sore is a kind of ulcerative damages illness for betiding mucous membrane of mouth, area very little, and be common in lip,
Inside cheek.Canker sore is many factors comprehensive function as a result, comprising: local trauma, stress, food
Object, drug, malnutrition, hormonal readiness change and vitamin or microelement deficiencies.It is systemic disease, heredity, immune and micro-
Biology may play an important role in the generation, development of canker sore.Such as lack trace element zinc, iron, lacks folic acid, vitamin
A possibility that B12 and malnutrition etc. can reduce immune function, increase canker sore morbidity；Streptococcus sanguis and helicobacter pylorus
The bacteriums such as bacterium are also in close relations with canker sore.Canker sore usually implies that body may have potential systemic disease, oral cavity
Ulcer and gastric ulcer, duodenal ulcer, ulcerative colitis, regional enteritis, hepatitis, female menstrual period, vitamin B complex absorb
Disfunction, vegetative nerve functional disturbance disease etc. are related.
Local treatment is the most common treatment method of recurrent oral ulceration at present, and nearly all patient requires to use.
Local treatment is with anti-inflammatory, analgesic, control infection, promotion healing for principle.Local application's common dosage forms have gargle, powder
Deng, but since the diluting effect that washes away of saliva in oral cavity makes these dosage forms tend not to locally keep effectively dense in ulcer surface
Degree.In short, recurrent oral ulceration remedy measures are inconvenient, therapeutic effect is bad, though traditional Chinese medical herbal treatment truly has curative effect, curative effect
Slowly, the course for the treatment of is long.Therefore, for how the above problem, it is necessary to propose further solution.
Summary of the invention
The present invention is in view of the deficienciess of the prior art, provide a kind of traditional Chinese medicine reagent and its preparation for curing mainly canker sore
Method.
The technical solution adopted by the present invention to solve the technical problems is:
A kind of traditional Chinese medicine reagent curing mainly canker sore, is made of sterilizing collutory and oral care potus, and sterilize collutory
It is refined glycerol, peppermint oil, lauryl sodium sulfate, big by natamycin, nisin, phenyllactic acid, sodium bicarbonate, biology
Beans oligosaccharide, different qualityxylans, freshener WS-23, calcium carbonate, disodium hydrogen phosphate and pure water composition, wherein each component uses
Mass content is natamycin 0.1%~0.3%, nisin 0.2%~0.4%, phenyllactic acid 0.1%~0.3%, carbon
Sour hydrogen sodium 0.05%~0.2%, biology are refined glycerol 0.05%~0.15%, peppermint oil 0.05%~0.15%, dodecyl
Sodium sulphate 0.05%~0.15%, soyabean oligosaccharides 0.05%~0.1%, different qualityxylans 0.02%~0.07%, freshener WS-
23 0.05%~0.15%, calcium carbonate 0.02%~0.07%, disodium hydrogen phosphate 0.05%~0.1%, surplus are pure water；
Oral care potus is by Radix Astragali, Radix Angelicae Sinensis, ramulus cinnamomi, Radix Paeoniae Alba, dark plum, burnt short, bristly hair or beard, cortex cinnamomi, radix aucklandiae, Hericium erinaceus, seaweed, Prunella vulgaris, Radix Glycyrrhizae
It is formed with deionized water, the mass parts ratio that wherein each component uses are as follows: 20-25 parts of Radix Astragali, 15-20 parts of Radix Angelicae Sinensis, ramulus cinnamomi 15-20
Part, 20-25 parts of Radix Paeoniae Alba, 10-15 parts of dark plum, burnt 5-10 parts of short, bristly hair or beard, 3-5 parts of cortex cinnamomi, 3-5 parts of radix aucklandiae, 3-5 parts of Hericium erinaceus, seaweed 5-8
Part, 3-5 parts of Prunella vulgaris, 15-20 parts of Radix Glycyrrhizae and 800~1200 parts of deionized water.
The preparation method of the above-mentioned traditional Chinese medicine reagent for curing mainly canker sore, steps are as follows for specific method:
(1) sterilizing collutory preparation, weighs formula rate for natamycin, nisin, phenyllactic acid and is added to 40
Sodium bicarbonate is added after stirring by reactor to dissolution in DEG C pure water, biology is refined glycerol, peppermint oil, dodecyl sulphate
Sodium, soyabean oligosaccharides, different qualityxylans, freshener WS-23, calcium carbonate and disodium hydrogen phosphate mixing, high-speed stirred to all components
Dissolution adjusts pH value between 6.6 to 7.1, obtains sterilizing collutory after passing through sterile filling after cooling；
(2) prepared by oral care potus, by Radix Astragali；Radix Angelicae Sinensis；Ramulus cinnamomi；Radix Paeoniae Alba；Dark plum；Burnt short, bristly hair or beard；Cortex cinnamomi；Radix aucklandiae；Hericium erinaceus；
Seaweed；Prunella vulgaris and Radix Glycyrrhizae weigh respectively according to the proportion, and then after nine steam nine solarizations, then these drugs are soaked in water by decocting
Extraction is boiled, has decocted all be filtered every time, filtrate is concentrated using cryogenic vacuum, high speed centrifugation precipitating is then carried out, takes supernatant
Liquid is spare, and deionized water is added in blending tank, then starting stirring supernatant obtained above is added to blending tank
In, it stirs evenly, the liquid sub-bottle in blending tank is filling, oral care potus can be obtained after high-temperature sterilization.
The present invention cures mainly the traditional Chinese medicine reagent of canker sore in use, first sterilizing collutory is contained in mouth, closes mouth, then
Two cheeks and lip are agitated, solution is made sufficiently and teeth contact, and repeatedly to rinse each position in oral cavity using waterpower in oral cavity,
Time is preferably at two minutes or so；Then it is at table after about half an hour and drinks oral care potus.
In traditional Chinese medicine reagent formula of the present invention: freshener WS-23 is N, 2,3- trimethyl -2- butanamide；Receive that he is mould
Element is the filamentous fungis inhibitor such as natural one kind, the saccharomycete of wide spectrum, highly effective and safe and mould, it can not only inhibit fungi,
The generation of mycotoxin can also be prevented, natamycin is harmless, is difficult to be absorbed by human body alimentary canal, and microorganism is difficult
Resistance is generated to it, the mechanism of action is to check ergosterol biology in conjunction with the ergosterol of fungi and other sterol groups
Synthesis, so that cell membrane be made to distort, eventually leads to leakage, causes cell death.Natamycin is especially for intraoral beads
Bacterium disease (being commonly called as thrush) has stronger sterilization and inhibiting effect；Benzene cream bacterium is a kind of natural biological antibacterial substance, to people and is moved
Object cytotoxic, phenyllactic acid has wide antimicrobial spectrum to fungi, to G+Bacterium, G-Bacterium and eukaryotic microorganisms have inhibition to make
With；The polypeptide compounds that nisin is made of 34 amino acid, the product as biofermentation can be used as nutrients
Matter is absorbed by the body utilization, and antibacterial action is the normal function by interfering cell v film, causes the infiltration of cell membrane, nutrient
It is lost and film potential declines, and have strong inhibiting effect to the spore of bacillus, it is thin so as to cause pathogenic bacteria and spoilage organisms
The death of born of the same parents；Radix Astragali has the effect of invigorating qi, consolidating exterior, promoting urination and detoxification, apocenosis, expelling pus and promoting granulation；Chinese angelica blood supplementing and blood, menstruction regulating and pain relieving,
Moisturizing dryness and lubricating intestine；Ramulus cinnamomi: sweating expelling pathogenic factors from muscles and skin, warming meridians and promoting circulation of qi, helps yang transforming qi, eliminating cold to stop pain；Radix Paeoniae Alba blood-supplementing blood-nourishing, holds back yin at suppressing liver-YANG
Hidroschesis；Dark plum astringing lung-QI, puckery intestines, promotes the production of body fluid, claming ascaris, there is the function of disinfection, is also prevented from food and degenerates in stomach；Burnt short, bristly hair or beard promoting digestion and removing indigestion
Promoting；The effect of cortex cinnamomi supplementing Yuanyang, warming spleen and stomach, removing internal cold, coronary circulation-promoting pain-relieving and antidiarrheal；Radix aucklandiae promoting qi circulation and relieving pain；Promoting in tune；Hedgehog hydnum
Mushroom is mild-natured, sweet in flavor, and relieving the five internal organs are aid digestion；With stomach invigorating, the effect of qi-restoratives, anticancer, kidney-nourishing is smart；Seaweed dissolving phlegm softening hard masses, dissipating bind disappear
It is swollen；Prunella vulgaris dissolving phlegm softening hard masses, mass dissipating and swelling eliminating；Radix Glycyrrhizae is clearing heat and detoxicating, expelling phlegm and arresting coughing.
The present invention provides two kinds of agents coordinates of sterilizing collutory and oral care potus according to canker sore pathology and uses,
Sterilizing collutory contains natamycin, nisin and phenyllactic acid, can effectively kill and inhibit the porphyromonas list in oral cavity
The G such as born of the same parents bacterium, bacterium actinomycetem comitans, Fusobacterium, streptococcus mutans+, G- bacterium, and the plaque bio-film generated simultaneously to flora has point
Solution effect, to the control of the bacterial flora for causing mouth disease of oral cavity ulcer margin and plaque bio-film and pre- on source
It is anti-；Oral care potus is by Radix Astragali simultaneously；Radix Angelicae Sinensis；Ramulus cinnamomi；Radix Paeoniae Alba；Dark plum；Burnt short, bristly hair or beard；Cortex cinnamomi；Radix aucklandiae；Hericium erinaceus and Radix Glycyrrhizae compatibility
Promote canker sore healing, mitigate pain, long-time service can enhance immunity of organisms, equilibrium between yin and yang be adjusted, to play entirety
Adjustment effect is to achieve the purpose that treat canker sore.
Specific embodiment
A kind of traditional Chinese medicine reagent curing mainly canker sore, is made of sterilizing collutory and oral care potus, and sterilize collutory
It is refined glycerol, peppermint oil, lauryl sodium sulfate, big by natamycin, nisin, phenyllactic acid, sodium bicarbonate, biology
Beans oligosaccharide, different qualityxylans, freshener WS-23, calcium carbonate, disodium hydrogen phosphate and pure water composition, wherein each component uses
Mass content is natamycin 0.1%~0.3%, nisin 0.2%~0.4%, phenyllactic acid 0.1%~0.3%, carbon
Sour hydrogen sodium 0.05%~0.2%, biology are refined glycerol 0.05%~0.15%, peppermint oil 0.05%~0.15%, dodecyl
Sodium sulphate 0.05%~0.15%, soyabean oligosaccharides 0.05%~0.1%, different qualityxylans 0.02%~0.07%, freshener WS-
23 0.05%~0.15%, calcium carbonate 0.02%~0.07%, disodium hydrogen phosphate 0.05%~0.1%, surplus are pure water；
Oral care potus is by Radix Astragali, Radix Angelicae Sinensis, ramulus cinnamomi, Radix Paeoniae Alba, dark plum, burnt short, bristly hair or beard, cortex cinnamomi, radix aucklandiae, Hericium erinaceus, seaweed, Prunella vulgaris, Radix Glycyrrhizae
It is formed with deionized water, the mass parts ratio that wherein each component uses are as follows: 20-25 parts of Radix Astragali, 15-20 parts of Radix Angelicae Sinensis, ramulus cinnamomi 15-20
Part, 20-25 parts of Radix Paeoniae Alba, 10-15 parts of dark plum, burnt 5-10 parts of short, bristly hair or beard, 3-5 parts of cortex cinnamomi, 3-5 parts of radix aucklandiae, 3-5 parts of Hericium erinaceus, seaweed 5-8
Part, 3-5 parts of Prunella vulgaris, 15-20 parts of Radix Glycyrrhizae and 800~1200 parts of deionized water.
The preparation method of the above-mentioned traditional Chinese medicine reagent for curing mainly canker sore, steps are as follows for specific method:
(1) sterilizing collutory preparation, weighs formula rate for natamycin, nisin, phenyllactic acid and is added to 40
Sodium bicarbonate is added after stirring by reactor to dissolution in DEG C pure water, biology is refined glycerol, peppermint oil, dodecyl sulphate
Sodium, soyabean oligosaccharides, different qualityxylans, freshener WS-23, calcium carbonate and disodium hydrogen phosphate mixing, high-speed stirred to all components
Dissolution adjusts pH value between 6.6 to 7.1, obtains sterilizing collutory after passing through sterile filling after cooling；
(2) prepared by oral care potus, by Radix Astragali；Radix Angelicae Sinensis；Ramulus cinnamomi；Radix Paeoniae Alba；Dark plum；Burnt short, bristly hair or beard；Cortex cinnamomi；Radix aucklandiae；Hericium erinaceus；
Seaweed；Prunella vulgaris and Radix Glycyrrhizae weigh respectively according to the proportion, and then after nine steam nine solarizations, then these drugs are soaked in water by decocting
Extraction is boiled, has decocted all be filtered every time, filtrate is concentrated using cryogenic vacuum, high speed centrifugation precipitating is then carried out, takes supernatant
Liquid is spare, and deionized water is added in blending tank, then starting stirring supernatant obtained above is added to blending tank
In, it stirs evenly, the liquid sub-bottle in blending tank is filling, oral care potus can be obtained after high-temperature sterilization.
The present invention cures mainly the traditional Chinese medicine reagent of canker sore in use, first sterilizing collutory is contained in mouth, closes mouth, then
Two cheeks and lip are agitated, solution is made sufficiently and teeth contact, and repeatedly to rinse each position in oral cavity using waterpower in oral cavity,
Time is preferably at two minutes or so；Then it is at table after about half an hour and drinks oral care potus.
Claims (2)
1. a kind of traditional Chinese medicine reagent for curing mainly canker sore sterilizes it is characterized in that being made of sterilizing collutory and oral care potus
Collutory is refined glycerol, peppermint oil, dodecyl sulphur by natamycin, nisin, phenyllactic acid, sodium bicarbonate, biology
Sour sodium, soyabean oligosaccharides, different qualityxylans, freshener WS-23, calcium carbonate, disodium hydrogen phosphate and pure water form, wherein each component
The mass content used be natamycin 0.1%~0.3%, nisin 0.2%~0.4%, phenyllactic acid 0.1%~
0.3%, sodium bicarbonate 0.05%~0.2%, biology refine glycerol 0.05%~0.15%, peppermint oil 0.05%~0.15%,
Lauryl sodium sulfate 0.05%~0.15%, soyabean oligosaccharides 0.05%~0.1%, different qualityxylans 0.02%~0.07%,
Freshener WS-23 0.05%~0.15%, calcium carbonate 0.02%~0.07%, disodium hydrogen phosphate 0.05%~0.1%, surplus
For pure water；Oral care potus is by Radix Astragali, Radix Angelicae Sinensis, ramulus cinnamomi, Radix Paeoniae Alba, dark plum, burnt short, bristly hair or beard, cortex cinnamomi, radix aucklandiae, Hericium erinaceus, seaweed, summer
Withered grass, Radix Glycyrrhizae and deionized water composition, the mass parts ratio that wherein each component uses are as follows: 20-25 parts of Radix Astragali, 15-20 parts of Radix Angelicae Sinensis, osmanthus
Branch 15-20 part, 20-25 parts of Radix Paeoniae Alba, 10-15 parts of dark plum, coke 5-10 parts of short, bristly hair or beard, 3-5 parts of cortex cinnamomi, 3-5 parts of radix aucklandiae, 3-5 parts of Hericium erinaceus,
5-8 parts of seaweed, 3-5 parts of Prunella vulgaris, 15-20 parts of Radix Glycyrrhizae and 800~1200 parts of deionized water.
2. the preparation method of the traditional Chinese medicine reagent described in claim 1 for curing mainly canker sore, it is characterized in that specific method step is such as
Under:
(1) sterilizing collutory preparation, by natamycin, nisin, phenyllactic acid weigh formula rate be added to 40 DEG C it is pure
Be added after being stirred by reactor to dissolution in water purification sodium bicarbonate, biology refine glycerol, peppermint oil, lauryl sodium sulfate,
Soyabean oligosaccharides, different qualityxylans, freshener WS-23, calcium carbonate and disodium hydrogen phosphate mixing, high-speed stirred are molten to all components
Solution adjusts pH value between 6.6 to 7.1, obtains sterilizing collutory after passing through sterile filling after cooling；
(2) prepared by oral care potus, by Radix Astragali；Radix Angelicae Sinensis；Ramulus cinnamomi；Radix Paeoniae Alba；Dark plum；Burnt short, bristly hair or beard；Cortex cinnamomi；Radix aucklandiae；Hericium erinaceus；Sea
Algae；Prunella vulgaris and Radix Glycyrrhizae weigh respectively according to the proportion, and then after nine steam nine solarizations, then these drugs are soaked in water by decocting
It extracts, has decocted all be filtered every time, filtrate is concentrated using cryogenic vacuum, high speed centrifugation precipitating is then carried out, takes supernatant
It is spare, deionized water is added in blending tank, then starting stirring supernatant obtained above is added into blending tank,
It stirs evenly, the liquid sub-bottle in blending tank is filling, oral care potus can be obtained after high-temperature sterilization.
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