CN109476641B - Cbp/ep300的杂环抑制剂及其在治疗癌症中的用途 - Google Patents

Cbp/ep300的杂环抑制剂及其在治疗癌症中的用途 Download PDF

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CN109476641B
CN109476641B CN201780045651.4A CN201780045651A CN109476641B CN 109476641 B CN109476641 B CN 109476641B CN 201780045651 A CN201780045651 A CN 201780045651A CN 109476641 B CN109476641 B CN 109476641B
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cancer
compound
methyl
formula
salt
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CN109476641A (zh
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P·西尔
S·布朗纳
F·A·罗梅罗
S·马格努森
V·H-W·徐
J·瓦伊
K·W·赖
F·王
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Genentech Inc
Constellation Pharmaceuticals Inc
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Constellation Pharmaceuticals Inc
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CN201780045651.4A 2016-05-24 2017-05-24 Cbp/ep300的杂环抑制剂及其在治疗癌症中的用途 Expired - Fee Related CN109476641B (zh)

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PCT/US2017/034320 WO2017205536A2 (en) 2016-05-24 2017-05-24 Therapeutic compounds and uses thereof

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CN110291089B (zh) 2017-01-17 2022-05-27 海帕瑞吉尼克斯股份有限公司 用于促进肝再生或者减少或预防肝细胞死亡的蛋白激酶抑制剂
CN110573501B (zh) * 2017-06-30 2023-09-29 北京泰德制药股份有限公司 Rho相关蛋白激酶抑制剂、包含其的药物组合物及其制备方法和用途
WO2019000683A1 (zh) 2017-06-30 2019-01-03 北京泰德制药股份有限公司 Rho相关蛋白激酶抑制剂、包含其的药物组合物及其制备方法和用途
AU2018294054B2 (en) * 2017-06-30 2022-05-26 Beijing Tide Pharmaceutical Co., Ltd. Rho-associated protein kinase inhibitor, pharmaceutical composition comprising same, and preparation method and use thereof
WO2019055877A1 (en) 2017-09-15 2019-03-21 Forma Therapeutics, Inc. TETRAHYDROIMIDAZO QUINOLINE COMPOSITIONS AS INHIBITORS OF CBP / P300
US11414384B2 (en) 2018-02-16 2022-08-16 Constellation Pharmaceuticals, Inc. P300/CBP hat inhibitors
RS65966B1 (sr) 2018-02-16 2024-10-31 Constellation Pharmaceuticals Inc Inhibitori p300/cbp hat
AU2019245403B2 (en) 2018-03-29 2025-02-06 Board Of Regents, The University Of Texas System Imidazopiperazine inhibitors of transcription activating proteins
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WO2019201291A1 (zh) * 2018-04-20 2019-10-24 中国科学院上海药物研究所 组蛋白乙酰转移酶(hat)抑制剂及其用途
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KR20250067962A (ko) 2018-06-29 2025-05-15 포르마 세라퓨틱스 인크. Creb 결합 단백질(cbp)의 저해
CN112770752A (zh) 2018-08-02 2021-05-07 波士顿大学董事会 晚期sv40因子(lsf)抑制剂
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