CN1090627C - 2－氨基－1,2－二氢化茚化合物其制备方法和药物组合物 - Google Patents
2－氨基－1,2－二氢化茚化合物其制备方法和药物组合物 Download PDFInfo
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- CN1090627C CN1090627C CN98107709A CN98107709A CN1090627C CN 1090627 C CN1090627 C CN 1090627C CN 98107709 A CN98107709 A CN 98107709A CN 98107709 A CN98107709 A CN 98107709A CN 1090627 C CN1090627 C CN 1090627C
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- Prior art keywords
- indane
- amino
- compound
- piperidines
- dihydro
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D411/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms
- C07D411/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D411/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
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- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Anesthesiology (AREA)
- Child & Adolescent Psychology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9702360 | 1997-02-27 | ||
| FR9702360A FR2760014B1 (fr) | 1997-02-27 | 1997-02-27 | Nouveaux composes de 2-amino indane, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1194983A CN1194983A (zh) | 1998-10-07 |
| CN1090627C true CN1090627C (zh) | 2002-09-11 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN98107709A Expired - Fee Related CN1090627C (zh) | 1997-02-27 | 1998-02-26 | 2－氨基－1,2－二氢化茚化合物其制备方法和药物组合物 |
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|---|---|
| US (1) | US5968954A (enExample) |
| EP (1) | EP0861837B1 (enExample) |
| JP (1) | JPH10237071A (enExample) |
| CN (1) | CN1090627C (enExample) |
| AT (1) | ATE265451T1 (enExample) |
| AU (1) | AU725756B2 (enExample) |
| BR (1) | BR9800763A (enExample) |
| CA (1) | CA2231025C (enExample) |
| DE (1) | DE69823411T2 (enExample) |
| DK (1) | DK0861837T3 (enExample) |
| ES (1) | ES2219853T3 (enExample) |
| FR (1) | FR2760014B1 (enExample) |
| HU (1) | HU224312B1 (enExample) |
| NO (1) | NO314307B1 (enExample) |
| NZ (1) | NZ329853A (enExample) |
| PL (1) | PL190240B1 (enExample) |
| PT (1) | PT861837E (enExample) |
| ZA (1) | ZA981680B (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI274750B (en) * | 1999-01-12 | 2007-03-01 | Abbott Gmbh & Co Kg | Triazole compounds showing high affinity to dopamine D3 receptor and pharmaceutical composition comprising the same |
| JP4280067B2 (ja) | 2001-01-16 | 2009-06-17 | アストラゼネカ・アクチエボラーグ | 治療用ヘテロ環式化合物 |
| SE0103650D0 (sv) * | 2001-11-01 | 2001-11-01 | Astrazeneca Ab | Therapeutic heterocyclic compounds |
| AU2002322539B2 (en) | 2001-07-20 | 2007-09-27 | Psychogenics Inc. | Treatment for attention-deficit hyperactivity disorder |
| JP2005343790A (ja) * | 2002-05-31 | 2005-12-15 | Ajinomoto Co Inc | カルシウムチャネル拮抗薬を含有する医薬組成物 |
| US20050165025A1 (en) * | 2004-01-22 | 2005-07-28 | Recordati Ireland Ltd. | Combination therapy with 5HT 1A and 5HT 1B-receptor antagonists |
| CA2587749A1 (en) * | 2004-12-08 | 2006-06-15 | Astellas Pharma Inc. | Piperidine derivative and process for producing the same |
| UY29892A1 (es) * | 2005-11-04 | 2007-06-29 | Astrazeneca Ab | Nuevos derivados de cromano, composiciones farmaceuticas conteniendolos, procesos de preparacion y aplicaciones |
| WO2020183011A1 (en) | 2019-03-14 | 2020-09-17 | Institut Curie | Htr1d inhibitors and uses thereof in the treatment of cancer |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995007274A1 (en) * | 1993-09-06 | 1995-03-16 | Knoll Ag | Bicyclic aromatic compounds as therapeutic agents |
| EP0745598A1 (fr) * | 1995-05-31 | 1996-12-04 | Adir Et Compagnie | Nouveaux composés de la pipérazine, de la pipéridine et de la 1,2,5,6-tétra-hydropyridine, leur procédé de préparation et les compositions pharmaceutiques les contenant |
-
1997
- 1997-02-27 FR FR9702360A patent/FR2760014B1/fr not_active Expired - Fee Related
-
1998
- 1998-02-24 PL PL98324982A patent/PL190240B1/pl not_active IP Right Cessation
- 1998-02-25 JP JP10042716A patent/JPH10237071A/ja active Pending
- 1998-02-25 BR BR9800763-7A patent/BR9800763A/pt not_active Application Discontinuation
- 1998-02-26 NZ NZ329853A patent/NZ329853A/xx unknown
- 1998-02-26 US US09/031,490 patent/US5968954A/en not_active Expired - Fee Related
- 1998-02-26 HU HU9800422A patent/HU224312B1/hu not_active IP Right Cessation
- 1998-02-26 CN CN98107709A patent/CN1090627C/zh not_active Expired - Fee Related
- 1998-02-26 CA CA002231025A patent/CA2231025C/fr not_active Expired - Fee Related
- 1998-02-26 NO NO19980803A patent/NO314307B1/no unknown
- 1998-02-27 PT PT98400469T patent/PT861837E/pt unknown
- 1998-02-27 AU AU56359/98A patent/AU725756B2/en not_active Ceased
- 1998-02-27 AT AT98400469T patent/ATE265451T1/de not_active IP Right Cessation
- 1998-02-27 ES ES98400469T patent/ES2219853T3/es not_active Expired - Lifetime
- 1998-02-27 DE DE69823411T patent/DE69823411T2/de not_active Expired - Fee Related
- 1998-02-27 EP EP98400469A patent/EP0861837B1/fr not_active Expired - Lifetime
- 1998-02-27 DK DK98400469T patent/DK0861837T3/da active
- 1998-02-27 ZA ZA981680A patent/ZA981680B/xx unknown
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995007274A1 (en) * | 1993-09-06 | 1995-03-16 | Knoll Ag | Bicyclic aromatic compounds as therapeutic agents |
| EP0745598A1 (fr) * | 1995-05-31 | 1996-12-04 | Adir Et Compagnie | Nouveaux composés de la pipérazine, de la pipéridine et de la 1,2,5,6-tétra-hydropyridine, leur procédé de préparation et les compositions pharmaceutiques les contenant |
Also Published As
| Publication number | Publication date |
|---|---|
| EP0861837B1 (fr) | 2004-04-28 |
| JPH10237071A (ja) | 1998-09-08 |
| AU5635998A (en) | 1998-09-03 |
| CA2231025A1 (fr) | 1998-08-27 |
| NO980803D0 (no) | 1998-02-26 |
| DE69823411T2 (de) | 2005-02-17 |
| DK0861837T3 (da) | 2004-08-16 |
| PT861837E (pt) | 2004-07-30 |
| HU224312B1 (hu) | 2005-07-28 |
| HK1014945A1 (en) | 1999-10-08 |
| AU725756B2 (en) | 2000-10-19 |
| BR9800763A (pt) | 1999-12-07 |
| ZA981680B (en) | 1998-09-04 |
| ATE265451T1 (de) | 2004-05-15 |
| US5968954A (en) | 1999-10-19 |
| DE69823411D1 (de) | 2004-06-03 |
| PL324982A1 (en) | 1998-08-31 |
| HU9800422D0 (en) | 1998-04-28 |
| ES2219853T3 (es) | 2004-12-01 |
| NO314307B1 (no) | 2003-03-03 |
| NZ329853A (en) | 1999-01-28 |
| HUP9800422A1 (hu) | 1999-12-28 |
| FR2760014B1 (fr) | 1999-04-09 |
| FR2760014A1 (fr) | 1998-08-28 |
| EP0861837A1 (fr) | 1998-09-02 |
| CN1194983A (zh) | 1998-10-07 |
| NO980803L (no) | 1998-08-28 |
| CA2231025C (fr) | 2003-09-16 |
| PL190240B1 (pl) | 2005-11-30 |
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